# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/MafB19-deam.hmm.txt # target sequence database: proteomes/Homo_sapiens.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: MafB19-deam [M=138] Accession: PF14437.5 Description: MafB19-like deaminase Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.4e-21 78.9 0.1 1.8e-21 78.6 0.1 1.1 1 sp|Q7Z6V5|ADAT2_HUMAN tRNA-specific adenosine deaminase 2 4.6e-14 54.6 0.0 5.1e-14 54.4 0.0 1.1 1 tr|D6RBJ9|D6RBJ9_HUMAN Deoxycytidylate deaminase (Fragment) 5.2e-14 54.4 0.0 6.1e-14 54.2 0.0 1.1 1 sp|P32321|DCTD_HUMAN Deoxycytidylate deaminase OS=Homo sa 6.2e-14 54.2 0.0 7.4e-14 53.9 0.0 1.1 1 sp|P32321-2|DCTD_HUMAN Isoform 2 of Deoxycytidylate deamina 2e-13 52.5 0.0 2.5e-13 52.2 0.0 1.2 1 sp|Q7Z6V5-2|ADAT2_HUMAN Isoform 2 of tRNA-specific adenosine 1.2e-11 46.7 0.6 0.00019 23.5 0.1 2.6 2 sp|Q9BWV3|CDAC1_HUMAN Cytidine and dCMP deaminase domain-c 2.3e-10 42.6 0.0 2.7e-10 42.4 0.0 1.1 1 tr|D6RBN2|D6RBN2_HUMAN Deoxycytidylate deaminase (Fragment) 1e-09 40.5 0.0 1.2e-09 40.3 0.0 1.1 1 tr|D6R9S0|D6R9S0_HUMAN Deoxycytidylate deaminase (Fragment) 5.6e-09 38.1 0.0 3.4e-07 32.3 0.0 2.1 2 sp|Q96EY9|ADAT3_HUMAN Probable inactive tRNA-specific aden 0.00013 24.0 0.0 0.00015 23.8 0.0 1.1 1 sp|Q9BWV3-4|CDAC1_HUMAN Isoform 4 of Cytidine and dCMP deami 0.00028 22.9 0.1 0.00041 22.3 0.1 1.3 1 tr|G8JLM2|G8JLM2_HUMAN Cytidine and dCMP deaminase domain-c 0.0022 20.0 0.4 0.0063 18.5 0.4 1.9 1 tr|F2Z2J8|F2Z2J8_HUMAN Cytidine and dCMP deaminase domain-c 0.0024 19.9 0.5 0.0079 18.2 0.3 1.9 1 sp|Q9BWV3-3|CDAC1_HUMAN Isoform 3 of Cytidine and dCMP deami 0.0094 18.0 0.0 0.012 17.6 0.0 1.1 1 tr|D6RC36|D6RC36_HUMAN Deoxycytidylate deaminase (Fragment) ------ inclusion threshold ------ 0.036 16.1 0.1 0.066 15.2 0.0 1.4 1 sp|Q9Y235|ABEC2_HUMAN Probable C->U-editing enzyme APOBEC- 0.31 13.0 0.1 0.5 12.3 0.1 1.3 1 tr|B1AJY7|B1AJY7_HUMAN 26S proteasome non-ATPase regulatory 0.49 12.4 0.2 0.68 11.9 0.2 1.1 1 sp|Q6NTF7-4|ABC3H_HUMAN Isoform 4 of DNA dC->dU-editing enzy 0.53 12.3 0.1 0.92 11.5 0.1 1.3 1 sp|O75832|PSD10_HUMAN 26S proteasome non-ATPase regulatory 0.63 12.0 0.1 0.95 11.4 0.1 1.2 1 sp|Q6NTF7-2|ABC3H_HUMAN Isoform 2 of DNA dC->dU-editing enzy 0.63 12.0 0.1 0.96 11.4 0.1 1.2 1 sp|Q6NTF7-3|ABC3H_HUMAN Isoform 3 of DNA dC->dU-editing enzy 0.74 11.8 0.1 1.1 11.2 0.1 1.2 1 sp|Q6NTF7|ABC3H_HUMAN DNA dC->dU-editing enzyme APOBEC-3H Domain annotation for each sequence (and alignments): >> sp|Q7Z6V5|ADAT2_HUMAN tRNA-specific adenosine deaminase 2 OS=Homo sapiens GN=ADAT2 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 78.6 0.1 4.3e-25 1.8e-21 2 136 .. 21 173 .. 20 175 .. 0.87 Alignments for each domain: == domain 1 score: 78.6 bits; conditional E-value: 4.3e-25 MafB19-deam 2 dkekafrkalaevekatkikedkigavivkdkkviargsnekelnakataHaEiaalqqAakklkskrl......ddatlyvtlepCd 83 + ek++++a+ ++++a++ +e+++g++ v +++v+++g ne ++ ++at HaE+ a+ q + ++ + + ++lyvt+epC sp|Q7Z6V5|ADAT2_HUMAN 21 ETEKWMEEAMHMAKEALENTEVPVGCLMVYNNEVVGKGRNEVNQTKNATRHAEMVAIDQVLDWCRQSGKspsevfEHTVLYVTVEPCI 108 679******************************************************999876655543222222789********** PP MafB19-deam 84 mCagaivqaglkklvygagnpks......lnkLkvkekngrvelv......eddckeilkgffkk 136 mCa a+ +++ +vyg++n+ + ln + +n+ + ++ e+lk f k+ sp|Q7Z6V5|ADAT2_HUMAN 109 MCAAALRLMKIPLVVYGCQNERFggcgsvLNIASADLPNTGRPFQcipgyrAEEAVEMLKTFYKQ 173 **********************99**999999999999999876688888866666888888776 PP >> tr|D6RBJ9|D6RBJ9_HUMAN Deoxycytidylate deaminase (Fragment) OS=Homo sapiens GN=DCTD PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 54.4 0.0 1.2e-17 5.1e-14 3 103 .. 15 131 .. 13 166 .. 0.83 Alignments for each domain: == domain 1 score: 54.4 bits; conditional E-value: 1.2e-17 MafB19-deam 3 kekafrkalaevekatkikedkigaviv.kdkkviargsn...................ekelnakataHaEiaalqqAakklkskr 69 + ++f+ +++ +++k + ++ga iv ++k++++g+n + +++ HaE +a++ s+ tr|D6RBJ9|D6RBJ9_HUMAN 15 WPEYFMAVAFLSAQRSKDPNSQVGACIVnSENKIVGIGYNgmpngcsddvlpwrrtaenKLDTKYPYVCHAELNAIMNK----NSTD 97 6789999999999999999999999666599***********************999655555566789*******975....4555 PP MafB19-deam 70 lddatlyvtlepCdmCagaivqaglkklvygagn 103 +++ +yv l pC+ Ca++i+qag+k++++ +++ tr|D6RBJ9|D6RBJ9_HUMAN 98 VKGCSMYVALFPCNECAKLIIQAGIKEVIFMSDK 131 89***************************98873 PP >> sp|P32321|DCTD_HUMAN Deoxycytidylate deaminase OS=Homo sapiens GN=DCTD PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 54.2 0.0 1.4e-17 6.1e-14 3 103 .. 15 131 .. 13 166 .. 0.83 Alignments for each domain: == domain 1 score: 54.2 bits; conditional E-value: 1.4e-17 MafB19-deam 3 kekafrkalaevekatkikedkigaviv.kdkkviargsn...................ekelnakataHaEiaalqqAakklkskrld 71 + ++f+ +++ +++k + ++ga iv ++k++++g+n + +++ HaE +a++ s+ + sp|P32321|DCTD_HUMAN 15 WPEYFMAVAFLSAQRSKDPNSQVGACIVnSENKIVGIGYNgmpngcsddvlpwrrtaenKLDTKYPYVCHAELNAIMNK----NSTDVK 99 6789999999999999999999999666599***********************999655555566789*******975....455589 PP MafB19-deam 72 datlyvtlepCdmCagaivqaglkklvygagn 103 ++ +yv l pC+ Ca++i+qag+k++++ +++ sp|P32321|DCTD_HUMAN 100 GCSMYVALFPCNECAKLIIQAGIKEVIFMSDK 131 ***************************98873 PP >> sp|P32321-2|DCTD_HUMAN Isoform 2 of Deoxycytidylate deaminase OS=Homo sapiens GN=DCTD # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 53.9 0.0 1.8e-17 7.4e-14 3 103 .. 26 142 .. 24 177 .. 0.83 Alignments for each domain: == domain 1 score: 53.9 bits; conditional E-value: 1.8e-17 MafB19-deam 3 kekafrkalaevekatkikedkigaviv.kdkkviargsn...................ekelnakataHaEiaalqqAakklkskr 69 + ++f+ +++ +++k + ++ga iv ++k++++g+n + +++ HaE +a++ s+ sp|P32321-2|DCTD_HUMAN 26 WPEYFMAVAFLSAQRSKDPNSQVGACIVnSENKIVGIGYNgmpngcsddvlpwrrtaenKLDTKYPYVCHAELNAIMNK----NSTD 108 6789999999999999999999999666599***********************999655555566789*******975....4555 PP MafB19-deam 70 lddatlyvtlepCdmCagaivqaglkklvygagn 103 +++ +yv l pC+ Ca++i+qag+k++++ +++ sp|P32321-2|DCTD_HUMAN 109 VKGCSMYVALFPCNECAKLIIQAGIKEVIFMSDK 142 89***************************98873 PP >> sp|Q7Z6V5-2|ADAT2_HUMAN Isoform 2 of tRNA-specific adenosine deaminase 2 OS=Homo sapiens GN=ADAT2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 52.2 0.0 5.9e-17 2.5e-13 30 136 .. 2 126 .. 1 128 [. 0.85 Alignments for each domain: == domain 1 score: 52.2 bits; conditional E-value: 5.9e-17 MafB19-deam 30 vkdkkviargsnekelnakataHaEiaalqqAakklkskrl......ddatlyvtlepCdmCagaivqaglkklvygagnpks... 106 v +++v+++g ne ++ ++at HaE+ a+ q + ++ + + ++lyvt+epC mCa a+ +++ +vyg++n+ + sp|Q7Z6V5-2|ADAT2_HUMAN 2 VYNNEVVGKGRNEVNQTKNATRHAEMVAIDQVLDWCRQSGKspsevfEHTVLYVTVEPCIMCAAALRLMKIPLVVYGCQNERFggc 87 5689*************************999876655543222222789********************************99** PP MafB19-deam 107 ...lnkLkvkekngrvelv......eddckeilkgffkk 136 ln + +n+ + ++ e+lk f k+ sp|Q7Z6V5-2|ADAT2_HUMAN 88 gsvLNIASADLPNTGRPFQcipgyrAEEAVEMLKTFYKQ 126 999999999999999876688999866666999888876 PP >> sp|Q9BWV3|CDAC1_HUMAN Cytidine and dCMP deaminase domain-containing protein 1 OS=Homo sapiens GN=CDADC1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.5 0.1 4.5e-08 0.00019 65 106 .. 118 158 .. 72 193 .. 0.78 2 ! 21.1 0.0 2.4e-07 0.001 49 101 .. 395 445 .. 322 469 .. 0.81 Alignments for each domain: == domain 1 score: 23.5 bits; conditional E-value: 4.5e-08 MafB19-deam 65 lkskrlddatlyvtlepCdmCagaivqaglkklvygagnpks 106 ++rl+++ ly ++pC+ C+++iv+ag+ ++ y ++p+ sp|Q9BWV3|CDAC1_HUMAN 118 H-GSRLKNCDLYFSRKPCSACLKMIVNAGVNRISYWPADPEI 158 3.4679***************************998887764 PP == domain 2 score: 21.1 bits; conditional E-value: 2.4e-07 MafB19-deam 49 ataHaEiaalqqAakklkskrlddatlyvtlepCdmCagaivqaglkklvyga 101 HaE +al ++ +k ++ +++vt+ pCd C +i ag+k++ g sp|Q9BWV3|CDAC1_HUMAN 395 YIIHAEQNALTFRCQEIKPE--ERSMIFVTKCPCDECVPLIKGAGIKQIYAGD 445 567**************999..9*************************98764 PP >> tr|D6RBN2|D6RBN2_HUMAN Deoxycytidylate deaminase (Fragment) OS=Homo sapiens GN=DCTD PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 42.4 0.0 6.4e-14 2.7e-10 3 92 .. 15 120 .] 13 120 .] 0.87 Alignments for each domain: == domain 1 score: 42.4 bits; conditional E-value: 6.4e-14 MafB19-deam 3 kekafrkalaevekatkikedkigaviv.kdkkviargsn...................ekelnakataHaEiaalqqAakklkskr 69 + ++f+ +++ +++k + ++ga iv ++k++++g+n + +++ HaE +a++ s+ tr|D6RBN2|D6RBN2_HUMAN 15 WPEYFMAVAFLSAQRSKDPNSQVGACIVnSENKIVGIGYNgmpngcsddvlpwrrtaenKLDTKYPYVCHAELNAIMNK----NSTD 97 6789999999999999999999999666599***********************999655555566789*******975....4555 PP MafB19-deam 70 lddatlyvtlepCdmCagaivqa 92 +++ +yv l pC+ Ca++i+qa tr|D6RBN2|D6RBN2_HUMAN 98 VKGCSMYVALFPCNECAKLIIQA 120 89********************8 PP >> tr|D6R9S0|D6R9S0_HUMAN Deoxycytidylate deaminase (Fragment) OS=Homo sapiens GN=DCTD PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 40.3 0.0 2.9e-13 1.2e-09 3 91 .. 15 119 .] 13 119 .] 0.87 Alignments for each domain: == domain 1 score: 40.3 bits; conditional E-value: 2.9e-13 MafB19-deam 3 kekafrkalaevekatkikedkigaviv.kdkkviargsn...................ekelnakataHaEiaalqqAakklkskr 69 + ++f+ +++ +++k + ++ga iv ++k++++g+n + +++ HaE +a++ s+ tr|D6R9S0|D6R9S0_HUMAN 15 WPEYFMAVAFLSAQRSKDPNSQVGACIVnSENKIVGIGYNgmpngcsddvlpwrrtaenKLDTKYPYVCHAELNAIMNK----NSTD 97 6789999999999999999999999666599***********************999655555566789*******975....4555 PP MafB19-deam 70 lddatlyvtlepCdmCagaivq 91 +++ +yv l pC+ Ca++i+q tr|D6R9S0|D6R9S0_HUMAN 98 VKGCSMYVALFPCNECAKLIIQ 119 89*******************8 PP >> sp|Q96EY9|ADAT3_HUMAN Probable inactive tRNA-specific adenosine deaminase-like protein 3 OS=Homo sapiens GN=ADAT3 PE # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.7 0.0 0.057 2.4e+02 4 52 .. 174 223 .. 171 240 .. 0.80 2 ! 32.3 0.0 8.1e-11 3.4e-07 75 126 .. 284 344 .. 262 347 .. 0.84 Alignments for each domain: == domain 1 score: 3.7 bits; conditional E-value: 0.057 MafB19-deam 4 ekafrkalaevekatkikedkigaviv..kdkkviargsnekelnakataH 52 + ++ a+ ++ a+ + + +gav+v ++v+a+g+ + +++ H sp|Q96EY9|ADAT3_HUMAN 174 QSHMERAVWAARRAAARGLRAVGAVVVdpASDRVLATGHD-CSCADNPLLH 223 55677778888999999999****99966789******98.4445555555 PP == domain 2 score: 32.3 bits; conditional E-value: 8.1e-11 MafB19-deam 75 lyvtlepCdmCagaivqaglkklvygagnpks..lnkLkvke...kngrvelv....eddc 126 lyvt+epC mCa a+v a++ ++ yga p++ ++ +++ n+r++++ e++c sp|Q96EY9|ADAT3_HUMAN 284 LYVTREPCAMCAMALVHARILRVFYGAPSPDGalGTRFRIHArpdLNHRFQVFrgvlEEQC 344 9******************************987567777652225888888877777766 PP >> sp|Q9BWV3-4|CDAC1_HUMAN Isoform 4 of Cytidine and dCMP deaminase domain-containing protein 1 OS=Homo sapiens GN=CDAD # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.8 0.0 3.6e-08 0.00015 51 101 .. 17 65 .. 4 92 .. 0.84 Alignments for each domain: == domain 1 score: 23.8 bits; conditional E-value: 3.6e-08 MafB19-deam 51 aHaEiaalqqAakklkskrlddatlyvtlepCdmCagaivqaglkklvyga 101 HaE +al ++ +k ++ +++vt+ pCd C +i ag+k++ g sp|Q9BWV3-4|CDAC1_HUMAN 17 IHAEQNALTFRCQEIKPE--ERSMIFVTKCPCDECVPLIKGAGIKQIYAGD 65 6**************999..9*************************98774 PP >> tr|G8JLM2|G8JLM2_HUMAN Cytidine and dCMP deaminase domain-containing protein 1 OS=Homo sapiens GN=CDADC1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.3 0.1 9.8e-08 0.00041 48 101 .. 196 247 .. 122 272 .. 0.80 Alignments for each domain: == domain 1 score: 22.3 bits; conditional E-value: 9.8e-08 MafB19-deam 48 kataHaEiaalqqAakklkskrlddatlyvtlepCdmCagaivqaglkklvyga 101 HaE +al ++ +k ++ +++vt+ pCd C +i ag+k++ g tr|G8JLM2|G8JLM2_HUMAN 196 RYIIHAEQNALTFRCQEIKPE--ERSMIFVTKCPCDECVPLIKGAGIKQIYAGD 247 4567**************999..9*************************98764 PP >> tr|F2Z2J8|F2Z2J8_HUMAN Cytidine and dCMP deaminase domain-containing protein 1 OS=Homo sapiens GN=CDADC1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.5 0.4 1.5e-06 0.0063 64 95 .. 117 147 .. 51 151 .. 0.79 Alignments for each domain: == domain 1 score: 18.5 bits; conditional E-value: 1.5e-06 MafB19-deam 64 klkskrlddatlyvtlepCdmCagaivqaglk 95 k ++rl+++ ly ++pC+ C+++iv++ l tr|F2Z2J8|F2Z2J8_HUMAN 117 KH-GSRLKNCDLYFSRKPCSACLKMIVNGLLE 147 33.4679*********************9875 PP >> sp|Q9BWV3-3|CDAC1_HUMAN Isoform 3 of Cytidine and dCMP deaminase domain-containing protein 1 OS=Homo sapiens GN=CDAD # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.2 0.3 1.9e-06 0.0079 65 95 .. 118 147 .. 72 151 .. 0.78 Alignments for each domain: == domain 1 score: 18.2 bits; conditional E-value: 1.9e-06 MafB19-deam 65 lkskrlddatlyvtlepCdmCagaivqaglk 95 ++rl+++ ly ++pC+ C+++iv++ l sp|Q9BWV3-3|CDAC1_HUMAN 118 H-GSRLKNCDLYFSRKPCSACLKMIVNGLLG 147 3.4679*********************9775 PP >> tr|D6RC36|D6RC36_HUMAN Deoxycytidylate deaminase (Fragment) OS=Homo sapiens GN=DCTD PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.6 0.0 2.8e-06 0.012 3 59 .. 15 91 .. 13 95 .. 0.86 Alignments for each domain: == domain 1 score: 17.6 bits; conditional E-value: 2.8e-06 MafB19-deam 3 kekafrkalaevekatkikedkigaviv.kdkkviargsn...................ekelnakataHaEiaalq 59 + ++f+ +++ +++k + ++ga iv ++k++++g+n + +++ HaE +a++ tr|D6RC36|D6RC36_HUMAN 15 WPEYFMAVAFLSAQRSKDPNSQVGACIVnSENKIVGIGYNgmpngcsddvlpwrrtaenKLDTKYPYVCHAELNAIM 91 6789999999999999999999999666599***********************999655555566789*******9 PP >> sp|Q9Y235|ABEC2_HUMAN Probable C->U-editing enzyme APOBEC-2 OS=Homo sapiens GN=APOBEC2 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.2 0.0 1.6e-05 0.066 42 91 .. 91 137 .. 61 150 .. 0.85 Alignments for each domain: == domain 1 score: 15.2 bits; conditional E-value: 1.6e-05 MafB19-deam 42 ekelnakataHaEiaalqqAakklkskrlddatlyvtlepCdmCagaivq 91 e +++a aHaE a ++ ++ ++t yv pC Ca i++ sp|Q9Y235|ABEC2_HUMAN 91 E---DEHAAAHAEEAFFNTILPAFDPALRYNVTWYVSSSPCAACADRIIK 137 3...45899*****9999999999999999***************99997 PP >> tr|B1AJY7|B1AJY7_HUMAN 26S proteasome non-ATPase regulatory subunit 10 OS=Homo sapiens GN=PSMD10 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.3 0.1 0.00012 0.5 14 68 .. 44 120 .. 34 130 .. 0.86 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 0.00012 MafB19-deam 14 vekatkikedkiga.vivkdkkviargsn.....................ekelnakataHaEiaalqqAakklksk 68 +++a++++ d i++ + k+ +v a+++n e n +a +H E+ a+ +Aa k+ k tr|B1AJY7|B1AJY7_HUMAN 44 LHIAASAGRDEIVKaLLGKGAQVNAVNQNgctplhyaasknrheiavmllEGGANPDAKDHYEATAMHRAAAKGNLK 120 56788899999988455599*****************************9888999**************9998655 PP >> sp|Q6NTF7-4|ABC3H_HUMAN Isoform 4 of DNA dC->dU-editing enzyme APOBEC-3H OS=Homo sapiens GN=APOBEC3H # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 0.2 0.00016 0.68 46 89 .. 48 92 .. 34 97 .. 0.79 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 0.00016 MafB19-deam 46 nakataHaEiaalqqAakkl.kskrlddatlyvtlepCdmCagai 89 ++k HaEi ++ + +++ ++t y t pC+ Ca + sp|Q6NTF7-4|ABC3H_HUMAN 48 ENKKKCHAEICFINEIKSMGlDETQCYQVTCYLTWSPCSSCAWEL 92 567889****9999886554145667899************9655 PP >> sp|O75832|PSD10_HUMAN 26S proteasome non-ATPase regulatory subunit 10 OS=Homo sapiens GN=PSMD10 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 0.1 0.00022 0.92 15 68 .. 78 153 .. 72 163 .. 0.86 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 0.00022 MafB19-deam 15 ekatkikedkiga.vivkdkkviargsn.....................ekelnakataHaEiaalqqAakklksk 68 ++a++++ d i++ + k+ +v a+++n e n +a +H E+ a+ +Aa k+ k sp|O75832|PSD10_HUMAN 78 HIAASAGRDEIVKaLLGKGAQVNAVNQNgctplhyaasknrheiavmllEGGANPDAKDHYEATAMHRAAAKGNLK 153 56788888888884555999****************************9888999**************9998655 PP >> sp|Q6NTF7-2|ABC3H_HUMAN Isoform 2 of DNA dC->dU-editing enzyme APOBEC-3H OS=Homo sapiens GN=APOBEC3H # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 0.1 0.00023 0.95 46 89 .. 48 92 .. 34 96 .. 0.79 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 0.00023 MafB19-deam 46 nakataHaEiaalqqAakkl.kskrlddatlyvtlepCdmCagai 89 ++k HaEi ++ + +++ ++t y t pC+ Ca + sp|Q6NTF7-2|ABC3H_HUMAN 48 ENKKKCHAEICFINEIKSMGlDETQCYQVTCYLTWSPCSSCAWEL 92 567889****9999886554145667899************9655 PP >> sp|Q6NTF7-3|ABC3H_HUMAN Isoform 3 of DNA dC->dU-editing enzyme APOBEC-3H OS=Homo sapiens GN=APOBEC3H # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 0.1 0.00023 0.96 46 89 .. 48 92 .. 34 96 .. 0.79 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 0.00023 MafB19-deam 46 nakataHaEiaalqqAakkl.kskrlddatlyvtlepCdmCagai 89 ++k HaEi ++ + +++ ++t y t pC+ Ca + sp|Q6NTF7-3|ABC3H_HUMAN 48 ENKKKCHAEICFINEIKSMGlDETQCYQVTCYLTWSPCSSCAWEL 92 567889****9999886554145667899************9655 PP >> sp|Q6NTF7|ABC3H_HUMAN DNA dC->dU-editing enzyme APOBEC-3H OS=Homo sapiens GN=APOBEC3H PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 0.1 0.00027 1.1 46 89 .. 48 92 .. 34 96 .. 0.79 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 0.00027 MafB19-deam 46 nakataHaEiaalqqAakkl.kskrlddatlyvtlepCdmCagai 89 ++k HaEi ++ + +++ ++t y t pC+ Ca + sp|Q6NTF7|ABC3H_HUMAN 48 ENKKKCHAEICFINEIKSMGlDETQCYQVTCYLTWSPCSSCAWEL 92 567888****9999886554145667899************9655 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (138 nodes) Target sequences: 88473 (35070517 residues searched) Passed MSV filter: 2404 (0.0271721); expected 1769.5 (0.02) Passed bias filter: 1599 (0.0180733); expected 1769.5 (0.02) Passed Vit filter: 134 (0.00151459); expected 88.5 (0.001) Passed Fwd filter: 21 (0.000237361); expected 0.9 (1e-05) Initial search space (Z): 88473 [actual number of targets] Domain search space (domZ): 21 [number of targets reported over threshold] # CPU time: 0.41u 0.02s 00:00:00.43 Elapsed: 00:00:00.21 # Mc/sec: 23046.34 // [ok]