# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/MafB19-deam.hmm.txt
# target sequence database:        proteomes/Macaca_mulatta.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       MafB19-deam  [M=138]
Accession:   PF14437.5
Description: MafB19-like deaminase
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence                       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------                       -----------
    4.4e-22   78.5   0.1    5.7e-22   78.2   0.1    1.2  1  tr|F7GAS0|F7GAS0_MACMU          Adenosine deaminase, tRNA specif
    1.2e-14   54.5   0.0    1.5e-14   54.2   0.0    1.1  1  tr|A0A1D5R474|A0A1D5R474_MACMU  Uncharacterized protein OS=Macac
      3e-12   46.7   0.6    4.5e-05   23.4   0.1    2.6  2  tr|F6ZM52|F6ZM52_MACMU          Cytidine and dCMP deaminase doma
    0.00012   22.0   0.0     0.0002   21.3   0.0    1.3  1  sp|Q19Q52|ABC3H_MACMU           DNA dC->dU-editing enzyme APOBEC
      0.001   19.1   0.0     0.0017   18.4   0.0    1.3  1  tr|A0A1D5QZU3|A0A1D5QZU3_MACMU  DNA dC->dU-editing enzyme APOBEC
  ------ inclusion threshold ------
      0.021   14.8   0.4       0.16   11.9   0.1    2.1  2  tr|F6XHA6|F6XHA6_MACMU          Uncharacterized protein OS=Macac
      0.025   14.6   0.0      0.061   13.3   0.0    1.5  1  tr|F7H6K4|F7H6K4_MACMU          Apolipoprotein B mRNA editing en
       0.13   12.3   0.1       0.22   11.5   0.1    1.3  1  tr|A0A1D5QZ92|A0A1D5QZ92_MACMU  26S proteasome non-ATPase regula


Domain annotation for each sequence (and alignments):
>> tr|F7GAS0|F7GAS0_MACMU  Adenosine deaminase, tRNA specific 2 OS=Macaca mulatta OX=9544 GN=ADAT2 PE=3 SV=2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   78.2   0.1   2.1e-25   5.7e-22       2     136 ..      21     173 ..      20     175 .. 0.87

  Alignments for each domain:
  == domain 1  score: 78.2 bits;  conditional E-value: 2.1e-25
             MafB19-deam   2 dkekafrkalaevekatkikedkigavivkdkkviargsnekelnakataHaEiaalqqAakklkskrl......ddatlyvtlepC 82 
                             + ek++++a+ ++++a++ +e+++g++ v +++v+++g ne ++ ++at HaE+ a+ q  +    + +      + ++lyvt+epC
  tr|F7GAS0|F7GAS0_MACMU  21 ETEKWMEEAMHMAKEALENTEVPVGCLMVYNNEVVGKGRNEVNQTKNATRHAEMVAIDQVLDWCRRSGKspsevfEHTVLYVTVEPC 107
                             679*******************************************************99875554433112222799********* PP

             MafB19-deam  83 dmCagaivqaglkklvygagnpks......lnkLkvkekngrvelv......eddckeilkgffkk 136
                              mCa a+   +++ +vyg++n+ +      ln  +   +n+ +          ++  e+lk f k+
  tr|F7GAS0|F7GAS0_MACMU 108 IMCAAALRLMKIPLVVYGCQNERFggcgsvLNIASADLPNTGRPFQcipgyrAEEAVEMLKTFYKQ 173
                             ***********************99**999999999999999876688888866666888888776 PP

>> tr|A0A1D5R474|A0A1D5R474_MACMU  Uncharacterized protein OS=Macaca mulatta OX=9544 GN=DCTD PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   54.2   0.0   5.5e-18   1.5e-14       3     103 ..      28     144 ..      26     180 .. 0.80

  Alignments for each domain:
  == domain 1  score: 54.2 bits;  conditional E-value: 5.5e-18
                     MafB19-deam   3 kekafrkalaevekatkikedkigaviv.kdkkviargsn...................ekelnakataHaEiaalqqA 61 
                                     + ++f+  +++  +++k  + ++ga iv  ++k++++g+n                   + +++     HaE +a++  
  tr|A0A1D5R474|A0A1D5R474_MACMU  28 WPEYFMAVAFLSAQRSKDPNSQVGACIVnSENKIVGIGYNgmpngcsddllpwsrtaenKLDTKYPYVCHAELNAIMNK 106
                                     6789999999999999999999999666599************************99655555566789*******975 PP

                     MafB19-deam  62 akklkskrlddatlyvtlepCdmCagaivqaglkklvygagn 103
                                          s+  +++ +yv l pC+ Ca++i+qag+k++++ +++
  tr|A0A1D5R474|A0A1D5R474_MACMU 107 ----NSTDVKGCSMYVALFPCNECAKLIIQAGIKEVIFMSDK 144
                                     ....455589***************************98873 PP

>> tr|F6ZM52|F6ZM52_MACMU  Cytidine and dCMP deaminase domain containing 1 OS=Macaca mulatta OX=9544 GN=CDADC1 PE=2 SV=2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.4   0.1   1.7e-08   4.5e-05      65     106 ..     119     159 ..      73     194 .. 0.78
   2 !   21.1   0.0   9.1e-08   0.00024      49     101 ..     396     446 ..     323     471 .. 0.81

  Alignments for each domain:
  == domain 1  score: 23.4 bits;  conditional E-value: 1.7e-08
             MafB19-deam  65 lkskrlddatlyvtlepCdmCagaivqaglkklvygagnpks 106
                               ++rl+++ ly  ++pC+ C+++iv+ag+ ++ y  ++p+ 
  tr|F6ZM52|F6ZM52_MACMU 119 H-GSRLKNCDLYFSRKPCSACLKMIVNAGVNRISYWPADPEI 159
                             3.4679***************************998887764 PP

  == domain 2  score: 21.1 bits;  conditional E-value: 9.1e-08
             MafB19-deam  49 ataHaEiaalqqAakklkskrlddatlyvtlepCdmCagaivqaglkklvyga 101
                                HaE +al   ++ +k    ++ +++vt+ pCd C  +i  ag+k++  g 
  tr|F6ZM52|F6ZM52_MACMU 396 YIIHAEQNALTFRCQEIKPE--ERSMIFVTKCPCDECVPLIKGAGIKQIYAGD 446
                             567**************999..9*************************98764 PP

>> sp|Q19Q52|ABC3H_MACMU  DNA dC->dU-editing enzyme APOBEC-3H OS=Macaca mulatta OX=9544 GN=APOBEC3H PE=1 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.3   0.0   7.7e-08    0.0002      42      90 ..      44      93 ..      24      97 .. 0.84

  Alignments for each domain:
  == domain 1  score: 21.3 bits;  conditional E-value: 7.7e-08
            MafB19-deam 42 ekelnakataHaEiaalqqAakkl.kskrlddatlyvtlepCdmCagaiv 90
                           +  l++k  +HaEi  +++    +  +++  ++t y t  pC+ Cag +v
  sp|Q19Q52|ABC3H_MACMU 44 RGHLKNKKKDHAEIRFINKIKSMGlDETQCYQVTCYLTWSPCPSCAGELV 93
                           677899*************96665145667899**************987 PP

>> tr|A0A1D5QZU3|A0A1D5QZU3_MACMU  DNA dC->dU-editing enzyme APOBEC-3H OS=Macaca mulatta OX=9544 GN=APOBEC3H PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.4   0.0   6.2e-07    0.0017      45      90 ..      61     107 ..      37     111 .. 0.83

  Alignments for each domain:
  == domain 1  score: 18.4 bits;  conditional E-value: 6.2e-07
                     MafB19-deam  45 lnakataHaEiaalqqAakkl.kskrlddatlyvtlepCdmCagaiv 90 
                                      n    +HaEi  +++    +  +++  ++t y t  pC+ Cag +v
  tr|A0A1D5QZU3|A0A1D5QZU3_MACMU  61 INTRKKDHAEIRFINKIKSMGlDETQCYQVTCYLTWSPCPSCAGELV 107
                                     5677889*********96665145667899**************987 PP

>> tr|F6XHA6|F6XHA6_MACMU  Uncharacterized protein OS=Macaca mulatta OX=9544 GN=APOBEC3D PE=4 SV=2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.6   0.1      0.19   5.1e+02      68      86 ..     102     120 ..      61     128 .. 0.73
   2 ?   11.9   0.1   6.1e-05      0.16      37      90 ..     232     308 ..     223     323 .. 0.76

  Alignments for each domain:
  == domain 1  score: 0.6 bits;  conditional E-value: 0.19
             MafB19-deam  68 krlddatlyvtlepCdmCa 86 
                              +  + t +v  +pC+ C 
  tr|F6XHA6|F6XHA6_MACMU 102 YKRFQITWFVSWNPCPDCV 120
                             455678999*********5 PP

  == domain 2  score: 11.9 bits;  conditional E-value: 6.1e-05
             MafB19-deam  37 argsn......................ekelnakataHaEiaalqqAakklks.krlddatlyvtlepCdmCagaiv 90 
                             +r+++                      +++++ ++  HaE   l   ++ + s k+  ++t y+   pC+ Cag ++
  tr|F6XHA6|F6XHA6_MACMU 232 GRNETwlcfaveiikqhstvpwktgvfRNQVDPETHCHAERCFLSWFCDNTLSpKKNYQVTWYISWSPCPECAGEVA 308
                             4444455555555555555555555559999999************99987661555689*************9765 PP

>> tr|F7H6K4|F7H6K4_MACMU  Apolipoprotein B mRNA editing enzyme catalytic subunit 2 OS=Macaca mulatta OX=9544 GN=APOBEC2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.0   2.3e-05     0.061      46      90 ..      92     136 ..      70     158 .. 0.81

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 2.3e-05
             MafB19-deam  46 nakataHaEiaalqqAakklkskrlddatlyvtlepCdmCagaiv 90 
                             +++a aHaE a ++    ++      ++t yv   pC  Ca  i 
  tr|F7H6K4|F7H6K4_MACMU  92 DEHAAAHAEEAFFNTILPAFDPALRYNVTWYVSSSPCAACADRIT 136
                             45899*****9999999999999999**************85554 PP

>> tr|A0A1D5QZ92|A0A1D5QZ92_MACMU  26S proteasome non-ATPase regulatory subunit 10 isoform 1 OS=Macaca mulatta OX=9544 G
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.1   8.3e-05      0.22      15      68 ..      78     153 ..      72     163 .. 0.86

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 8.3e-05
                     MafB19-deam  15 ekatkikedkiga.vivkdkkviargsn.....................ekelnakataHaEiaalqqAakklksk 68 
                                     ++a++++ d i++ +  k+ +v a+++n                     e   n +a +H E+ a+ +Aa k+  k
  tr|A0A1D5QZ92|A0A1D5QZ92_MACMU  78 HIAASAGRDEIVKaLLGKGAQVNAVNQNgctplhyaasknrheiavmllEGGANPDAKDHYEATAMHRAAAKGNLK 153
                                     56788888888884555999****************************9888999**************9998655 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (138 nodes)
Target sequences:                        21211  (10888574 residues searched)
Passed MSV filter:                       606  (0.0285701); expected 424.2 (0.02)
Passed bias filter:                      406  (0.019141); expected 424.2 (0.02)
Passed Vit filter:                        39  (0.00183867); expected 21.2 (0.001)
Passed Fwd filter:                         8  (0.000377163); expected 0.2 (1e-05)
Initial search space (Z):              21211  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.14u 0.01s 00:00:00.15 Elapsed: 00:00:00.08
# Mc/sec: 18782.79
//
[ok]