# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/MafB19-deam.hmm.txt # target sequence database: proteomes/Macaca_mulatta.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: MafB19-deam [M=138] Accession: PF14437.5 Description: MafB19-like deaminase Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.4e-22 78.5 0.1 5.7e-22 78.2 0.1 1.2 1 tr|F7GAS0|F7GAS0_MACMU Adenosine deaminase, tRNA specif 1.2e-14 54.5 0.0 1.5e-14 54.2 0.0 1.1 1 tr|A0A1D5R474|A0A1D5R474_MACMU Uncharacterized protein OS=Macac 3e-12 46.7 0.6 4.5e-05 23.4 0.1 2.6 2 tr|F6ZM52|F6ZM52_MACMU Cytidine and dCMP deaminase doma 0.00012 22.0 0.0 0.0002 21.3 0.0 1.3 1 sp|Q19Q52|ABC3H_MACMU DNA dC->dU-editing enzyme APOBEC 0.001 19.1 0.0 0.0017 18.4 0.0 1.3 1 tr|A0A1D5QZU3|A0A1D5QZU3_MACMU DNA dC->dU-editing enzyme APOBEC ------ inclusion threshold ------ 0.021 14.8 0.4 0.16 11.9 0.1 2.1 2 tr|F6XHA6|F6XHA6_MACMU Uncharacterized protein OS=Macac 0.025 14.6 0.0 0.061 13.3 0.0 1.5 1 tr|F7H6K4|F7H6K4_MACMU Apolipoprotein B mRNA editing en 0.13 12.3 0.1 0.22 11.5 0.1 1.3 1 tr|A0A1D5QZ92|A0A1D5QZ92_MACMU 26S proteasome non-ATPase regula Domain annotation for each sequence (and alignments): >> tr|F7GAS0|F7GAS0_MACMU Adenosine deaminase, tRNA specific 2 OS=Macaca mulatta OX=9544 GN=ADAT2 PE=3 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 78.2 0.1 2.1e-25 5.7e-22 2 136 .. 21 173 .. 20 175 .. 0.87 Alignments for each domain: == domain 1 score: 78.2 bits; conditional E-value: 2.1e-25 MafB19-deam 2 dkekafrkalaevekatkikedkigavivkdkkviargsnekelnakataHaEiaalqqAakklkskrl......ddatlyvtlepC 82 + ek++++a+ ++++a++ +e+++g++ v +++v+++g ne ++ ++at HaE+ a+ q + + + + ++lyvt+epC tr|F7GAS0|F7GAS0_MACMU 21 ETEKWMEEAMHMAKEALENTEVPVGCLMVYNNEVVGKGRNEVNQTKNATRHAEMVAIDQVLDWCRRSGKspsevfEHTVLYVTVEPC 107 679*******************************************************99875554433112222799********* PP MafB19-deam 83 dmCagaivqaglkklvygagnpks......lnkLkvkekngrvelv......eddckeilkgffkk 136 mCa a+ +++ +vyg++n+ + ln + +n+ + ++ e+lk f k+ tr|F7GAS0|F7GAS0_MACMU 108 IMCAAALRLMKIPLVVYGCQNERFggcgsvLNIASADLPNTGRPFQcipgyrAEEAVEMLKTFYKQ 173 ***********************99**999999999999999876688888866666888888776 PP >> tr|A0A1D5R474|A0A1D5R474_MACMU Uncharacterized protein OS=Macaca mulatta OX=9544 GN=DCTD PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 54.2 0.0 5.5e-18 1.5e-14 3 103 .. 28 144 .. 26 180 .. 0.80 Alignments for each domain: == domain 1 score: 54.2 bits; conditional E-value: 5.5e-18 MafB19-deam 3 kekafrkalaevekatkikedkigaviv.kdkkviargsn...................ekelnakataHaEiaalqqA 61 + ++f+ +++ +++k + ++ga iv ++k++++g+n + +++ HaE +a++ tr|A0A1D5R474|A0A1D5R474_MACMU 28 WPEYFMAVAFLSAQRSKDPNSQVGACIVnSENKIVGIGYNgmpngcsddllpwsrtaenKLDTKYPYVCHAELNAIMNK 106 6789999999999999999999999666599************************99655555566789*******975 PP MafB19-deam 62 akklkskrlddatlyvtlepCdmCagaivqaglkklvygagn 103 s+ +++ +yv l pC+ Ca++i+qag+k++++ +++ tr|A0A1D5R474|A0A1D5R474_MACMU 107 ----NSTDVKGCSMYVALFPCNECAKLIIQAGIKEVIFMSDK 144 ....455589***************************98873 PP >> tr|F6ZM52|F6ZM52_MACMU Cytidine and dCMP deaminase domain containing 1 OS=Macaca mulatta OX=9544 GN=CDADC1 PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.4 0.1 1.7e-08 4.5e-05 65 106 .. 119 159 .. 73 194 .. 0.78 2 ! 21.1 0.0 9.1e-08 0.00024 49 101 .. 396 446 .. 323 471 .. 0.81 Alignments for each domain: == domain 1 score: 23.4 bits; conditional E-value: 1.7e-08 MafB19-deam 65 lkskrlddatlyvtlepCdmCagaivqaglkklvygagnpks 106 ++rl+++ ly ++pC+ C+++iv+ag+ ++ y ++p+ tr|F6ZM52|F6ZM52_MACMU 119 H-GSRLKNCDLYFSRKPCSACLKMIVNAGVNRISYWPADPEI 159 3.4679***************************998887764 PP == domain 2 score: 21.1 bits; conditional E-value: 9.1e-08 MafB19-deam 49 ataHaEiaalqqAakklkskrlddatlyvtlepCdmCagaivqaglkklvyga 101 HaE +al ++ +k ++ +++vt+ pCd C +i ag+k++ g tr|F6ZM52|F6ZM52_MACMU 396 YIIHAEQNALTFRCQEIKPE--ERSMIFVTKCPCDECVPLIKGAGIKQIYAGD 446 567**************999..9*************************98764 PP >> sp|Q19Q52|ABC3H_MACMU DNA dC->dU-editing enzyme APOBEC-3H OS=Macaca mulatta OX=9544 GN=APOBEC3H PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.3 0.0 7.7e-08 0.0002 42 90 .. 44 93 .. 24 97 .. 0.84 Alignments for each domain: == domain 1 score: 21.3 bits; conditional E-value: 7.7e-08 MafB19-deam 42 ekelnakataHaEiaalqqAakkl.kskrlddatlyvtlepCdmCagaiv 90 + l++k +HaEi +++ + +++ ++t y t pC+ Cag +v sp|Q19Q52|ABC3H_MACMU 44 RGHLKNKKKDHAEIRFINKIKSMGlDETQCYQVTCYLTWSPCPSCAGELV 93 677899*************96665145667899**************987 PP >> tr|A0A1D5QZU3|A0A1D5QZU3_MACMU DNA dC->dU-editing enzyme APOBEC-3H OS=Macaca mulatta OX=9544 GN=APOBEC3H PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.4 0.0 6.2e-07 0.0017 45 90 .. 61 107 .. 37 111 .. 0.83 Alignments for each domain: == domain 1 score: 18.4 bits; conditional E-value: 6.2e-07 MafB19-deam 45 lnakataHaEiaalqqAakkl.kskrlddatlyvtlepCdmCagaiv 90 n +HaEi +++ + +++ ++t y t pC+ Cag +v tr|A0A1D5QZU3|A0A1D5QZU3_MACMU 61 INTRKKDHAEIRFINKIKSMGlDETQCYQVTCYLTWSPCPSCAGELV 107 5677889*********96665145667899**************987 PP >> tr|F6XHA6|F6XHA6_MACMU Uncharacterized protein OS=Macaca mulatta OX=9544 GN=APOBEC3D PE=4 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.6 0.1 0.19 5.1e+02 68 86 .. 102 120 .. 61 128 .. 0.73 2 ? 11.9 0.1 6.1e-05 0.16 37 90 .. 232 308 .. 223 323 .. 0.76 Alignments for each domain: == domain 1 score: 0.6 bits; conditional E-value: 0.19 MafB19-deam 68 krlddatlyvtlepCdmCa 86 + + t +v +pC+ C tr|F6XHA6|F6XHA6_MACMU 102 YKRFQITWFVSWNPCPDCV 120 455678999*********5 PP == domain 2 score: 11.9 bits; conditional E-value: 6.1e-05 MafB19-deam 37 argsn......................ekelnakataHaEiaalqqAakklks.krlddatlyvtlepCdmCagaiv 90 +r+++ +++++ ++ HaE l ++ + s k+ ++t y+ pC+ Cag ++ tr|F6XHA6|F6XHA6_MACMU 232 GRNETwlcfaveiikqhstvpwktgvfRNQVDPETHCHAERCFLSWFCDNTLSpKKNYQVTWYISWSPCPECAGEVA 308 4444455555555555555555555559999999************99987661555689*************9765 PP >> tr|F7H6K4|F7H6K4_MACMU Apolipoprotein B mRNA editing enzyme catalytic subunit 2 OS=Macaca mulatta OX=9544 GN=APOBEC2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 0.0 2.3e-05 0.061 46 90 .. 92 136 .. 70 158 .. 0.81 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 2.3e-05 MafB19-deam 46 nakataHaEiaalqqAakklkskrlddatlyvtlepCdmCagaiv 90 +++a aHaE a ++ ++ ++t yv pC Ca i tr|F7H6K4|F7H6K4_MACMU 92 DEHAAAHAEEAFFNTILPAFDPALRYNVTWYVSSSPCAACADRIT 136 45899*****9999999999999999**************85554 PP >> tr|A0A1D5QZ92|A0A1D5QZ92_MACMU 26S proteasome non-ATPase regulatory subunit 10 isoform 1 OS=Macaca mulatta OX=9544 G # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 0.1 8.3e-05 0.22 15 68 .. 78 153 .. 72 163 .. 0.86 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 8.3e-05 MafB19-deam 15 ekatkikedkiga.vivkdkkviargsn.....................ekelnakataHaEiaalqqAakklksk 68 ++a++++ d i++ + k+ +v a+++n e n +a +H E+ a+ +Aa k+ k tr|A0A1D5QZ92|A0A1D5QZ92_MACMU 78 HIAASAGRDEIVKaLLGKGAQVNAVNQNgctplhyaasknrheiavmllEGGANPDAKDHYEATAMHRAAAKGNLK 153 56788888888884555999****************************9888999**************9998655 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (138 nodes) Target sequences: 21211 (10888574 residues searched) Passed MSV filter: 606 (0.0285701); expected 424.2 (0.02) Passed bias filter: 406 (0.019141); expected 424.2 (0.02) Passed Vit filter: 39 (0.00183867); expected 21.2 (0.001) Passed Fwd filter: 8 (0.000377163); expected 0.2 (1e-05) Initial search space (Z): 21211 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.14u 0.01s 00:00:00.15 Elapsed: 00:00:00.08 # Mc/sec: 18782.79 // [ok]