# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/MafB19-deam.hmm.txt
# target sequence database: proteomes/Mus_musculus.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: MafB19-deam [M=138]
Accession: PF14437.5
Description: MafB19-like deaminase
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
7.5e-21 74.6 0.1 9.7e-21 74.3 0.1 1.2 1 sp|Q6P6J0|ADAT2_MOUSE tRNA-specific adenosine deaminase 2 OS
1.4e-14 54.3 0.0 1.6e-14 54.1 0.0 1.1 1 sp|Q8K2D6|DCTD_MOUSE Deoxycytidylate deaminase OS=Mus muscu
1.6e-12 47.7 0.8 6.8e-05 22.9 0.2 3.0 2 sp|Q8BMD5|CDAC1_MOUSE Cytidine and dCMP deaminase domain-con
1.4e-11 44.6 0.0 7e-11 42.3 0.0 1.9 1 sp|Q6PAT0|ADAT3_MOUSE Probable inactive tRNA-specific adenos
0.0035 17.4 0.0 0.0056 16.7 0.0 1.4 1 sp|Q9WV35|ABEC2_MOUSE C->U-editing enzyme APOBEC-2 OS=Mus mu
------ inclusion threshold ------
0.054 13.6 0.1 2.1 8.4 0.1 2.2 2 sp|Q99J72|ABEC3_MOUSE DNA dC->dU-editing enzyme APOBEC-3 OS=
0.9 9.6 3.5 1.3 9.1 3.5 1.2 1 sp|P12656|TSHB_MOUSE Thyrotropin subunit beta OS=Mus muscul
Domain annotation for each sequence (and alignments):
>> sp|Q6P6J0|ADAT2_MOUSE tRNA-specific adenosine deaminase 2 OS=Mus musculus OX=10090 GN=Adat2 PE=1 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 74.3 0.1 3e-24 9.7e-21 2 136 .. 21 173 .. 20 175 .. 0.85
Alignments for each domain:
== domain 1 score: 74.3 bits; conditional E-value: 3e-24
MafB19-deam 2 dkekafrkalaevekatkikedkigavivkdkkviargsnekelnakataHaEiaalqqAakklkskrl......ddatlyvtlepCd 83
+ ek++++a+ ++++a++ e+++g++ v +++v+++g ne ++ ++at HaE+ a+ q + + + + ++lyvt+epC
sp|Q6P6J0|ADAT2_MOUSE 21 ETEKWMEEAMRMAKEALENIEVPVGCLMVYNNEVVGKGRNEVNQTKNATRHAEMVAIDQVLDWCHQHGQspstvfEHTVLYVTVEPCI 108
579********************************************************98866554331111227899********* PP
MafB19-deam 84 mCagaivqaglkklvygagnpks......lnkLkvkekngrvelv......eddckeilkgffkk 136
mCa a+ +++ +vyg++n+ + ln + +n+ + ++ e+lk f k+
sp|Q6P6J0|ADAT2_MOUSE 109 MCAAALRLMKIPLVVYGCQNERFggcgsvLNIASADLPNTGRPFQcipgyrAEEAVELLKTFYKQ 173
*********************99999999888888888888866677777755555777777765 PP
>> sp|Q8K2D6|DCTD_MOUSE Deoxycytidylate deaminase OS=Mus musculus OX=10090 GN=Dctd PE=2 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 54.1 0.0 5.1e-18 1.6e-14 3 103 .. 15 131 .. 13 166 .. 0.81
Alignments for each domain:
== domain 1 score: 54.1 bits; conditional E-value: 5.1e-18
MafB19-deam 3 kekafrkalaevekatkikedkigaviv.kdkkviargsn...................ekelnakataHaEiaalqqAakklkskrld 71
+ ++f+ +++ +++k + ++ga iv ++k++++g+n + +++ HaE +a++ +++ +
sp|Q8K2D6|DCTD_MOUSE 15 WPEYFMAVAFLSAQRSKDPSSQVGACIVnTENKIVGIGYNgmpngcsddllpwrrtaenKLDTKYPYVCHAELNAIMNK---NSA-DVK 99
6789999999999999999999999666599***********************999655555566789*******974...444.479 PP
MafB19-deam 72 datlyvtlepCdmCagaivqaglkklvygagn 103
++ +yv l pC+ Ca++i+qag+k++++ +++
sp|Q8K2D6|DCTD_MOUSE 100 GCSMYVALFPCNECAKLIIQAGIKEVIFMSDK 131
***************************99873 PP
>> sp|Q8BMD5|CDAC1_MOUSE Cytidine and dCMP deaminase domain-containing protein 1 OS=Mus musculus OX=10090 GN=Cdadc1 PE=
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 22.9 0.2 2.1e-08 6.8e-05 66 105 .. 119 158 .. 73 184 .. 0.76
2 ! 21.5 0.0 5.9e-08 0.00019 48 102 .. 395 447 .. 324 474 .. 0.77
Alignments for each domain:
== domain 1 score: 22.9 bits; conditional E-value: 2.1e-08
MafB19-deam 66 kskrlddatlyvtlepCdmCagaivqaglkklvygagnpk 105
++rl+++ ly ++pC+ C+++iv+ag+ ++ y ++p+
sp|Q8BMD5|CDAC1_MOUSE 119 HGSRLKNCDLYFSRKPCSACLKMIVNAGVNRISYWPSDPE 158
35679***************************99887665 PP
== domain 2 score: 21.5 bits; conditional E-value: 5.9e-08
MafB19-deam 48 kataHaEiaalqqAakklkskrlddatlyvtlepCdmCagaivqaglkklvygag 102
HaE +al ++ +k ++ +++vt+ pCd C +i ag+k++ g
sp|Q8BMD5|CDAC1_MOUSE 395 RYIIHAEQNALTFRCQDIKPE--ERSMIFVTKCPCDECVPLIKGAGIKQIYAGDV 447
4567**************999..9*************************987754 PP
>> sp|Q6PAT0|ADAT3_MOUSE Probable inactive tRNA-specific adenosine deaminase-like protein 3 OS=Mus musculus OX=10090 GN
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 42.3 0.0 2.2e-14 7e-11 4 128 .. 174 344 .. 171 346 .. 0.84
Alignments for each domain:
== domain 1 score: 42.3 bits; conditional E-value: 2.2e-14
MafB19-deam 4 ekafrkalaevekatkikedkigaviv..kdkkviargsn...................................ekelnakataHaE 54
+ ++ a+ ++ a+ ++ + +gav+v ++v+a+g+ ++a at+ a
sp|Q6PAT0|ADAT3_MOUSE 174 QTHMERAVCAAQRAAAQGLRAVGAVVVdpASDRVLATGHDcssvaspllhavmvcidlvaqgqgrgscdlrshpaCSFTQATATQGAR 261
5567788888999999999*****99966789********999999999999999999999999999999988885666788999999 PP
MafB19-deam 55 iaalqqAakklkskrlddatlyvtlepCdmCagaivqaglkklvygagnpks....lnkLkvk.ekngrvelv....eddcke 128
+ ++++ + + lyvt+epC mCa a+v a+++++ yga p++ l +++ n+r++++ ed+c +
sp|Q6PAT0|ADAT3_MOUSE 262 AGSVRKLDEDSLPYVCTGYDLYVTREPCVMCAMALVHARIQRVFYGAPSPDGalgtLFRVHARpDLNHRFQVFrgilEDQCRQ 344
99999998888888888888*******************************99554333333225799*99998888888865 PP
>> sp|Q9WV35|ABEC2_MOUSE C->U-editing enzyme APOBEC-2 OS=Mus musculus OX=10090 GN=Apobec2 PE=1 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 16.7 0.0 1.8e-06 0.0056 28 91 .. 76 137 .. 60 192 .. 0.79
Alignments for each domain:
== domain 1 score: 16.7 bits; conditional E-value: 1.8e-06
MafB19-deam 28 vivkdkkviar.gsnekelnakataHaEiaalqqAakklkskrlddatlyvtlepCdmCagaivq 91
v++k+++ a+ g+ +++a+aHaE a ++ ++ + ++t yv pC Ca i +
sp|Q9WV35|ABEC2_MOUSE 76 VQSKGGQAQATqGYL---EDEHAGAHAEEAFFNTILPAFDPALKYNVTWYVSSSPCAACADRILK 137
444444444431333...3569*******999999999*********************865543 PP
>> sp|Q99J72|ABEC3_MOUSE DNA dC->dU-editing enzyme APOBEC-3 OS=Mus musculus OX=10090 GN=Apobec3 PE=1 SV=3
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 2.6 0.0 0.04 1.3e+02 63 91 .. 97 125 .. 72 127 .. 0.70
2 ? 8.4 0.1 0.00065 2.1 48 86 .. 295 331 .. 290 338 .. 0.77
Alignments for each domain:
== domain 1 score: 2.6 bits; conditional E-value: 0.04
MafB19-deam 63 kklkskrlddatlyvtlepCdmCagaivq 91
k l+ + + t y pC Ca iv+
sp|Q99J72|ABEC3_MOUSE 97 KVLSPREEFKITWYMSWSPCFECAEQIVR 125
4445555567899***********99996 PP
== domain 2 score: 8.4 bits; conditional E-value: 0.00065
MafB19-deam 48 kataHaEiaalqqAakklkskrlddatlyvtlepCdmCa 86
k +HaEi l + s+ t y t pC+ Ca
sp|Q99J72|ABEC3_MOUSE 295 KGKQHAEILFLDKIRSMELSQ--VTITCYLTWSPCPNCA 331
567899999998874443333..67889**********8 PP
>> sp|P12656|TSHB_MOUSE Thyrotropin subunit beta OS=Mus musculus OX=10090 GN=Tshb PE=2 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 9.1 3.5 0.0004 1.3 60 91 .. 17 43 .. 12 57 .. 0.77
Alignments for each domain:
== domain 1 score: 9.1 bits; conditional E-value: 0.0004
MafB19-deam 60 qAakklkskrlddatlyvtlepCdmCagaivq 91
qAa + + + + t+yv++ C +C + ++
sp|P12656|TSHB_MOUSE 17 QAASFCIPT---EYTMYVDRRECAYC--LTIN 43
555555555...89************..4555 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (138 nodes)
Target sequences: 22289 (11757923 residues searched)
Passed MSV filter: 665 (0.0298353); expected 445.8 (0.02)
Passed bias filter: 437 (0.0196061); expected 445.8 (0.02)
Passed Vit filter: 33 (0.00148055); expected 22.3 (0.001)
Passed Fwd filter: 7 (0.000314056); expected 0.2 (1e-05)
Initial search space (Z): 22289 [actual number of targets]
Domain search space (domZ): 7 [number of targets reported over threshold]
# CPU time: 0.14u 0.01s 00:00:00.15 Elapsed: 00:00:00.07
# Mc/sec: 23179.91
//
[ok]