# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/MafB19-deam.hmm.txt
# target sequence database:        proteomes/Nematostella_vectensis.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       MafB19-deam  [M=138]
Accession:   PF14437.5
Description: MafB19-like deaminase
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
      2e-18   66.9   0.0    2.2e-18   66.8   0.0    1.2  1  tr|A7S1Z0|A7S1Z0_NEMVE  Predicted protein OS=Nematostella vec
      1e-16   61.4   0.2      1e-16   61.3   0.2    1.0  1  tr|A7S1Z2|A7S1Z2_NEMVE  Predicted protein OS=Nematostella vec
      5e-14   52.7   0.0    6.3e-14   52.3   0.0    1.2  1  tr|A7SGH8|A7SGH8_NEMVE  Predicted protein OS=Nematostella vec
    3.1e-12   46.9   0.0    4.1e-06   27.0   0.0    2.5  2  tr|A7SGR7|A7SGR7_NEMVE  Predicted protein OS=Nematostella vec
      9e-12   45.4   0.1    4.7e-06   26.8   0.0    2.3  2  tr|A7RLD8|A7RLD8_NEMVE  Predicted protein OS=Nematostella vec
    2.8e-10   40.5   0.0    2.3e-05   24.6   0.0    2.4  2  tr|A7RT49|A7RT49_NEMVE  Predicted protein OS=Nematostella vec
    1.8e-08   34.6   0.6    2.4e-07   31.0   0.0    2.1  2  tr|A7SKU7|A7SKU7_NEMVE  Predicted protein (Fragment) OS=Nemat
  ------ inclusion threshold ------
       0.24   11.6  15.5        7.2    6.8   0.4    4.3  4  tr|A7SK40|A7SK40_NEMVE  Predicted protein (Fragment) OS=Nemat


Domain annotation for each sequence (and alignments):
>> tr|A7S1Z0|A7S1Z0_NEMVE  Predicted protein OS=Nematostella vectensis OX=45351 GN=v1g205539 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   66.8   0.0   7.2e-22   2.2e-18      22     103 ..      25     106 ..       4     149 .. 0.88

  Alignments for each domain:
  == domain 1  score: 66.8 bits;  conditional E-value: 7.2e-22
             MafB19-deam  22 edkigavivkdkkviargsnekelnakataHaEiaalqqAakklkskrlddatlyvtlepCdmCagaivqaglkklvygagn 103
                             + + gavi kd+k+ia   n   +n ++taHaE+ a++qA+ +lks  l ++ ly+   pC mC  ai  a + ++ y+a +
  tr|A7S1Z0|A7S1Z0_NEMVE  25 GMPFGAVIAKDNKIIAETANLSFVNCDPTAHAEVSAIRQACSALKSRDLTGCDLYTSCYPCAMCMAAIYWASISRVYYAAPK 106
                             5799************************************************************************999874 PP

>> tr|A7S1Z2|A7S1Z2_NEMVE  Predicted protein OS=Nematostella vectensis OX=45351 GN=v1g101232 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   61.3   0.2   3.4e-20     1e-16      16      90 ..      18      93 ..       3      96 .] 0.87

  Alignments for each domain:
  == domain 1  score: 61.3 bits;  conditional E-value: 3.4e-20
             MafB19-deam 16 katkik.edkigavivkdkkviargsnekelnakataHaEiaalqqAakklkskrlddatlyvtlepCdmCagaiv 90
                            ++++++ + + gavi kd+k+ia   n   +n ++taHaE+ a++qA+ +lks  l ++ ly+   pC mC  ai 
  tr|A7S1Z2|A7S1Z2_NEMVE 18 EGSDQGlGTPFGAVITKDNKIIAETANLSFVNCDPTAHAEVSAIRQACSALKSRDLTGCDLYTSCYPCAMCMAAIY 93
                            55555435799************************************************************99886 PP

>> tr|A7SGH8|A7SGH8_NEMVE  Predicted protein OS=Nematostella vectensis OX=45351 GN=v1g233184 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.3   0.0   2.1e-17   6.3e-14       2     102 ..      48     164 ..      47     197 .. 0.86

  Alignments for each domain:
  == domain 1  score: 52.3 bits;  conditional E-value: 2.1e-17
             MafB19-deam   2 dkekafrkalaevekatkikedkigaviv.kdkkviargsn...................ekelnakataHaEiaalqqAakklksk 68 
                             +++++f++ +++  +++k  + ++ga iv k++k++++g+n                   e +++     HaE++a+     k+++ 
  tr|A7SGH8|A7SGH8_NEMVE  48 SWDDYFMSVAFLSAQRSKDPSSQVGACIVnKERKIVGIGYNgmpngcsddelpwnrhaddELDTKYPYVCHAEMNAILN---KNSAD 131
                             699*********************996665999************************9554445555789*****9964...45544 PP

             MafB19-deam  69 rlddatlyvtlepCdmCagaivqaglkklvygag 102
                               +++t+yv l pC+ C ++i+qaglk++v+ ++
  tr|A7SGH8|A7SGH8_NEMVE 132 -VKGCTVYVALFPCNECSKIIIQAGLKEVVFVSD 164
                             .89***************************9887 PP

>> tr|A7SGR7|A7SGR7_NEMVE  Predicted protein OS=Nematostella vectensis OX=45351 GN=v1g212049 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.2   0.0   1.4e-06    0.0043      49      99 ..     146     195 ..      93     206 .. 0.76
   2 !   27.0   0.0   1.4e-09   4.1e-06      18     117 ..     357     475 ..     338     498 .. 0.81

  Alignments for each domain:
  == domain 1  score: 17.2 bits;  conditional E-value: 1.4e-06
             MafB19-deam  49 ataHaEiaalqqAakklkskrlddatlyvtlepCdmCagaivqaglkklvy 99 
                               +H  ++a+  A   +  +r+ + t+yv ++pC  C +++++ ++k++ y
  tr|A7SGR7|A7SGR7_NEMVE 146 DFSHDNMHAVTSA-LIGNPIRARGGTVYVSRKPCTFCIKLLAELKIKRIFY 195
                             4569999999999.6788899**************************9987 PP

  == domain 2  score: 27.0 bits;  conditional E-value: 1.4e-09
             MafB19-deam  18 tkikedkigavivkdkkviargsn....................ekelnakataHaEiaalqqAakklkskrlddatlyvtlepCdm 84 
                             ++   + +gavi k++ +++ g n                     k+ +     H+E  ++     ++ +++ + +t++v + pCd 
  tr|A7SGR7|A7SGR7_NEMVE 357 SDDPTRGVGAVILKENSIVGAGWNcytsdalygdfpraaskhvhIKNKRYPFSIHGEQSVILHR--FVTDIKDESTTIFVNKMPCDE 441
                             34445669*********************************9976666777788*******987..9999999************** PP

             MafB19-deam  85 Cagaivqaglkklvygagnpks.lnkLkvkekng 117
                             C  ++ + g+k++v+  ++ k   ++Lkv+   +
  tr|A7SGR7|A7SGR7_NEMVE 442 CVPLMLRVGVKNVVFPPEKAKKfHTQLKVNLLKT 475
                             **************99887665645555544333 PP

>> tr|A7RLD8|A7RLD8_NEMVE  Predicted protein OS=Nematostella vectensis OX=45351 GN=v1g198805 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.8   0.0   1.5e-09   4.7e-06      64     107 ..      90     141 ..      88     168 .. 0.82
   2 !   16.3   0.0   2.8e-06    0.0086       7     102 ..     290     400 ..     283     423 .. 0.79

  Alignments for each domain:
  == domain 1  score: 26.8 bits;  conditional E-value: 1.5e-09
             MafB19-deam  64 klkskrlddatlyvtlepCdmCagaivqaglkklvygagnpks........l 107
                             k+++ r +++t+y  + pC++C ++++qag+ k+ y   +p+         +
  tr|A7RLD8|A7RLD8_NEMVE  90 KFGQERYKGCTVYLSRRPCSYCTKLLIQAGVVKVYYLPTEPEVndpqdikaV 141
                             788999****************************997776665555554444 PP

  == domain 2  score: 16.3 bits;  conditional E-value: 2.8e-06
             MafB19-deam   7 frkalaevekatkikedkigavivkdkkviargsn............ekelnakataHa.EiaalqqAakkl..kskrlddatlyvt 78 
                             +   +++++++++   + +g+v + +++vi +g              +   ++    Ha E a+l +  + +  ++   + a ly+ 
  tr|A7RLD8|A7RLD8_NEMVE 290 MTRLAQMLSQRSDDPIRGVGCVLMYENEVISIGWSgfpakatygefpRSACKKPYIIHAaENAVLTKNQQIIrkADCLTSSAQLYIS 376
                             44556677888888888999*************99999******9997777777778852666776665554113456899****** PP

             MafB19-deam  79 lepCdmCagaivqaglkklvygag 102
                             + pC  C  ++v+ g+k+++  ++
  tr|A7RLD8|A7RLD8_NEMVE 377 KIPCRECVHMLVEVGVKHVILPGS 400
                             ******************987555 PP

>> tr|A7RT49|A7RT49_NEMVE  Predicted protein OS=Nematostella vectensis OX=45351 GN=v1g201752 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.5   0.0   1.9e-05     0.059      67      99 ..      99     130 ..      44     154 .. 0.89
   2 !   24.6   0.0   7.4e-09   2.3e-05      10      98 ..     283     392 ..     273     398 .. 0.88

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 1.9e-05
             MafB19-deam  67 skrlddatlyvtlepCdmCagaivqaglkklvy 99 
                             +k  +++t+y    pC  Ca+ + q g+kk+ y
  tr|A7RT49|A7RT49_NEMVE  99 DK-IKGCTVYLSSFPCASCAKFLTQFGVKKVYY 130
                             33.789************************987 PP

  == domain 2  score: 24.6 bits;  conditional E-value: 7.4e-09
             MafB19-deam  10 alaevekatkikedkigavivkdkkviargsn.......................ekelnakataHaEiaalqqAakklkskrldda 73 
                              +++++ a++  ++ ig+vi kd++ ++ g n                       +++l+     HaE +a+      + ++   ++
  tr|A7RT49|A7RT49_NEMVE 283 VAQLLSYASDDPHVGIGCVITKDRELVGFGWNhflnggygtfpqasdspdfshvsKDQLKYPFVVHAEQNAIISR--NTRDISGPGT 367
                             567788899999******************************************999999999********8654..56666667** PP

             MafB19-deam  74 tlyvtlepCdmCagaivqaglkklv 98 
                             t++ t+ pCd C  ++   g+k+ v
  tr|A7RT49|A7RT49_NEMVE 368 TMFATRSPCDECMPLLLGVGVKRFV 392
                             ************9999888888765 PP

>> tr|A7SKU7|A7SKU7_NEMVE  Predicted protein (Fragment) OS=Nematostella vectensis OX=45351 GN=v1g122036 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.1   0.1     0.067   2.1e+02       6      53 ..     138     186 ..     133     203 .. 0.77
   2 !   31.0   0.0   7.8e-11   2.4e-07      75     122 ..     232     285 ..     210     291 .] 0.77

  Alignments for each domain:
  == domain 1  score: 2.1 bits;  conditional E-value: 0.067
             MafB19-deam   6 afrkalaevekatkikedkiga..vivkdkkviargsnekelnakataHa 53 
                             + r a++ ++ a +++++ iga  v+ + k+v+a++   +  + ++++Ha
  tr|A7SKU7|A7SKU7_NEMVE 138 YVRFAQQAAQYAKSKQQVGIGAamVDPETKRVVAVACDLRH-HGHPLQHA 186
                             66677888888999999999997788899*****9987444.66677776 PP

  == domain 2  score: 31.0 bits;  conditional E-value: 7.8e-11
             MafB19-deam  75 lyvtlepCdmCagaivqaglkklvygagnpks.......lnkLkv.kekngrvelv 122
                             lyvt+epC mCa a+v ++++++ y +g+  s         kL++ k+ n+++e++
  tr|A7SKU7|A7SKU7_NEMVE 232 LYVTQEPCVMCAMALVHSRIRRVFYSCGD--SirgalgsKYKLHTqKALNHHFEVF 285
                             8***************************4..4346766633333314457776665 PP

>> tr|A7SK40|A7SK40_NEMVE  Predicted protein (Fragment) OS=Nematostella vectensis OX=45351 GN=v1g57497 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.8   0.4    0.0024       7.2      72      86 ..      12      26 ..       5      32 .. 0.86
   2 ?    5.1   0.6    0.0076        23      72      86 ..      36      50 ..      32      55 .. 0.85
   3 ?    6.1   0.4     0.004        12      73      86 ..      62      75 ..      57      81 .. 0.84
   4 ?    5.3   0.9    0.0068        21      72      86 ..      73      87 ..      65      93 .. 0.83

  Alignments for each domain:
  == domain 1  score: 6.8 bits;  conditional E-value: 0.0024
             MafB19-deam 72 datlyvtlepCdmCa 86
                            ++tly+t+ p + C 
  tr|A7SK40|A7SK40_NEMVE 12 GCTLYITHHPTPGCT 26
                            79************5 PP

  == domain 2  score: 5.1 bits;  conditional E-value: 0.0076
             MafB19-deam 72 datlyvtlepCdmCa 86
                            ++tly+t+ p + C 
  tr|A7SK40|A7SK40_NEMVE 36 GCTLYITHYPTPGCT 50
                            69************5 PP

  == domain 3  score: 6.1 bits;  conditional E-value: 0.004
             MafB19-deam 73 atlyvtlepCdmCa 86
                            +tly+t+ p + C 
  tr|A7SK40|A7SK40_NEMVE 62 CTLYITHHPTPGCT 75
                            9************5 PP

  == domain 4  score: 5.3 bits;  conditional E-value: 0.0068
             MafB19-deam 72 datlyvtlepCdmCa 86
                            ++tly+t+ p + C 
  tr|A7SK40|A7SK40_NEMVE 73 GCTLYITHYPTPGCT 87
                            79***********95 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (138 nodes)
Target sequences:                        24428  (8257945 residues searched)
Passed MSV filter:                       730  (0.0298837); expected 488.6 (0.02)
Passed bias filter:                      459  (0.0187899); expected 488.6 (0.02)
Passed Vit filter:                        33  (0.00135091); expected 24.4 (0.001)
Passed Fwd filter:                         9  (0.00036843); expected 0.2 (1e-05)
Initial search space (Z):              24428  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.12u 0.01s 00:00:00.13 Elapsed: 00:00:00.05
# Mc/sec: 22791.93
//
[ok]