# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/MafB19-deam.hmm.txt # target sequence database: proteomes/Nematostella_vectensis.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: MafB19-deam [M=138] Accession: PF14437.5 Description: MafB19-like deaminase Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2e-18 66.9 0.0 2.2e-18 66.8 0.0 1.2 1 tr|A7S1Z0|A7S1Z0_NEMVE Predicted protein OS=Nematostella vec 1e-16 61.4 0.2 1e-16 61.3 0.2 1.0 1 tr|A7S1Z2|A7S1Z2_NEMVE Predicted protein OS=Nematostella vec 5e-14 52.7 0.0 6.3e-14 52.3 0.0 1.2 1 tr|A7SGH8|A7SGH8_NEMVE Predicted protein OS=Nematostella vec 3.1e-12 46.9 0.0 4.1e-06 27.0 0.0 2.5 2 tr|A7SGR7|A7SGR7_NEMVE Predicted protein OS=Nematostella vec 9e-12 45.4 0.1 4.7e-06 26.8 0.0 2.3 2 tr|A7RLD8|A7RLD8_NEMVE Predicted protein OS=Nematostella vec 2.8e-10 40.5 0.0 2.3e-05 24.6 0.0 2.4 2 tr|A7RT49|A7RT49_NEMVE Predicted protein OS=Nematostella vec 1.8e-08 34.6 0.6 2.4e-07 31.0 0.0 2.1 2 tr|A7SKU7|A7SKU7_NEMVE Predicted protein (Fragment) OS=Nemat ------ inclusion threshold ------ 0.24 11.6 15.5 7.2 6.8 0.4 4.3 4 tr|A7SK40|A7SK40_NEMVE Predicted protein (Fragment) OS=Nemat Domain annotation for each sequence (and alignments): >> tr|A7S1Z0|A7S1Z0_NEMVE Predicted protein OS=Nematostella vectensis OX=45351 GN=v1g205539 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 66.8 0.0 7.2e-22 2.2e-18 22 103 .. 25 106 .. 4 149 .. 0.88 Alignments for each domain: == domain 1 score: 66.8 bits; conditional E-value: 7.2e-22 MafB19-deam 22 edkigavivkdkkviargsnekelnakataHaEiaalqqAakklkskrlddatlyvtlepCdmCagaivqaglkklvygagn 103 + + gavi kd+k+ia n +n ++taHaE+ a++qA+ +lks l ++ ly+ pC mC ai a + ++ y+a + tr|A7S1Z0|A7S1Z0_NEMVE 25 GMPFGAVIAKDNKIIAETANLSFVNCDPTAHAEVSAIRQACSALKSRDLTGCDLYTSCYPCAMCMAAIYWASISRVYYAAPK 106 5799************************************************************************999874 PP >> tr|A7S1Z2|A7S1Z2_NEMVE Predicted protein OS=Nematostella vectensis OX=45351 GN=v1g101232 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 61.3 0.2 3.4e-20 1e-16 16 90 .. 18 93 .. 3 96 .] 0.87 Alignments for each domain: == domain 1 score: 61.3 bits; conditional E-value: 3.4e-20 MafB19-deam 16 katkik.edkigavivkdkkviargsnekelnakataHaEiaalqqAakklkskrlddatlyvtlepCdmCagaiv 90 ++++++ + + gavi kd+k+ia n +n ++taHaE+ a++qA+ +lks l ++ ly+ pC mC ai tr|A7S1Z2|A7S1Z2_NEMVE 18 EGSDQGlGTPFGAVITKDNKIIAETANLSFVNCDPTAHAEVSAIRQACSALKSRDLTGCDLYTSCYPCAMCMAAIY 93 55555435799************************************************************99886 PP >> tr|A7SGH8|A7SGH8_NEMVE Predicted protein OS=Nematostella vectensis OX=45351 GN=v1g233184 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 52.3 0.0 2.1e-17 6.3e-14 2 102 .. 48 164 .. 47 197 .. 0.86 Alignments for each domain: == domain 1 score: 52.3 bits; conditional E-value: 2.1e-17 MafB19-deam 2 dkekafrkalaevekatkikedkigaviv.kdkkviargsn...................ekelnakataHaEiaalqqAakklksk 68 +++++f++ +++ +++k + ++ga iv k++k++++g+n e +++ HaE++a+ k+++ tr|A7SGH8|A7SGH8_NEMVE 48 SWDDYFMSVAFLSAQRSKDPSSQVGACIVnKERKIVGIGYNgmpngcsddelpwnrhaddELDTKYPYVCHAEMNAILN---KNSAD 131 699*********************996665999************************9554445555789*****9964...45544 PP MafB19-deam 69 rlddatlyvtlepCdmCagaivqaglkklvygag 102 +++t+yv l pC+ C ++i+qaglk++v+ ++ tr|A7SGH8|A7SGH8_NEMVE 132 -VKGCTVYVALFPCNECSKIIIQAGLKEVVFVSD 164 .89***************************9887 PP >> tr|A7SGR7|A7SGR7_NEMVE Predicted protein OS=Nematostella vectensis OX=45351 GN=v1g212049 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.2 0.0 1.4e-06 0.0043 49 99 .. 146 195 .. 93 206 .. 0.76 2 ! 27.0 0.0 1.4e-09 4.1e-06 18 117 .. 357 475 .. 338 498 .. 0.81 Alignments for each domain: == domain 1 score: 17.2 bits; conditional E-value: 1.4e-06 MafB19-deam 49 ataHaEiaalqqAakklkskrlddatlyvtlepCdmCagaivqaglkklvy 99 +H ++a+ A + +r+ + t+yv ++pC C +++++ ++k++ y tr|A7SGR7|A7SGR7_NEMVE 146 DFSHDNMHAVTSA-LIGNPIRARGGTVYVSRKPCTFCIKLLAELKIKRIFY 195 4569999999999.6788899**************************9987 PP == domain 2 score: 27.0 bits; conditional E-value: 1.4e-09 MafB19-deam 18 tkikedkigavivkdkkviargsn....................ekelnakataHaEiaalqqAakklkskrlddatlyvtlepCdm 84 ++ + +gavi k++ +++ g n k+ + H+E ++ ++ +++ + +t++v + pCd tr|A7SGR7|A7SGR7_NEMVE 357 SDDPTRGVGAVILKENSIVGAGWNcytsdalygdfpraaskhvhIKNKRYPFSIHGEQSVILHR--FVTDIKDESTTIFVNKMPCDE 441 34445669*********************************9976666777788*******987..9999999************** PP MafB19-deam 85 Cagaivqaglkklvygagnpks.lnkLkvkekng 117 C ++ + g+k++v+ ++ k ++Lkv+ + tr|A7SGR7|A7SGR7_NEMVE 442 CVPLMLRVGVKNVVFPPEKAKKfHTQLKVNLLKT 475 **************99887665645555544333 PP >> tr|A7RLD8|A7RLD8_NEMVE Predicted protein OS=Nematostella vectensis OX=45351 GN=v1g198805 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.8 0.0 1.5e-09 4.7e-06 64 107 .. 90 141 .. 88 168 .. 0.82 2 ! 16.3 0.0 2.8e-06 0.0086 7 102 .. 290 400 .. 283 423 .. 0.79 Alignments for each domain: == domain 1 score: 26.8 bits; conditional E-value: 1.5e-09 MafB19-deam 64 klkskrlddatlyvtlepCdmCagaivqaglkklvygagnpks........l 107 k+++ r +++t+y + pC++C ++++qag+ k+ y +p+ + tr|A7RLD8|A7RLD8_NEMVE 90 KFGQERYKGCTVYLSRRPCSYCTKLLIQAGVVKVYYLPTEPEVndpqdikaV 141 788999****************************997776665555554444 PP == domain 2 score: 16.3 bits; conditional E-value: 2.8e-06 MafB19-deam 7 frkalaevekatkikedkigavivkdkkviargsn............ekelnakataHa.EiaalqqAakkl..kskrlddatlyvt 78 + +++++++++ + +g+v + +++vi +g + ++ Ha E a+l + + + ++ + a ly+ tr|A7RLD8|A7RLD8_NEMVE 290 MTRLAQMLSQRSDDPIRGVGCVLMYENEVISIGWSgfpakatygefpRSACKKPYIIHAaENAVLTKNQQIIrkADCLTSSAQLYIS 376 44556677888888888999*************99999******9997777777778852666776665554113456899****** PP MafB19-deam 79 lepCdmCagaivqaglkklvygag 102 + pC C ++v+ g+k+++ ++ tr|A7RLD8|A7RLD8_NEMVE 377 KIPCRECVHMLVEVGVKHVILPGS 400 ******************987555 PP >> tr|A7RT49|A7RT49_NEMVE Predicted protein OS=Nematostella vectensis OX=45351 GN=v1g201752 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.5 0.0 1.9e-05 0.059 67 99 .. 99 130 .. 44 154 .. 0.89 2 ! 24.6 0.0 7.4e-09 2.3e-05 10 98 .. 283 392 .. 273 398 .. 0.88 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 1.9e-05 MafB19-deam 67 skrlddatlyvtlepCdmCagaivqaglkklvy 99 +k +++t+y pC Ca+ + q g+kk+ y tr|A7RT49|A7RT49_NEMVE 99 DK-IKGCTVYLSSFPCASCAKFLTQFGVKKVYY 130 33.789************************987 PP == domain 2 score: 24.6 bits; conditional E-value: 7.4e-09 MafB19-deam 10 alaevekatkikedkigavivkdkkviargsn.......................ekelnakataHaEiaalqqAakklkskrldda 73 +++++ a++ ++ ig+vi kd++ ++ g n +++l+ HaE +a+ + ++ ++ tr|A7RT49|A7RT49_NEMVE 283 VAQLLSYASDDPHVGIGCVITKDRELVGFGWNhflnggygtfpqasdspdfshvsKDQLKYPFVVHAEQNAIISR--NTRDISGPGT 367 567788899999******************************************999999999********8654..56666667** PP MafB19-deam 74 tlyvtlepCdmCagaivqaglkklv 98 t++ t+ pCd C ++ g+k+ v tr|A7RT49|A7RT49_NEMVE 368 TMFATRSPCDECMPLLLGVGVKRFV 392 ************9999888888765 PP >> tr|A7SKU7|A7SKU7_NEMVE Predicted protein (Fragment) OS=Nematostella vectensis OX=45351 GN=v1g122036 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.1 0.1 0.067 2.1e+02 6 53 .. 138 186 .. 133 203 .. 0.77 2 ! 31.0 0.0 7.8e-11 2.4e-07 75 122 .. 232 285 .. 210 291 .] 0.77 Alignments for each domain: == domain 1 score: 2.1 bits; conditional E-value: 0.067 MafB19-deam 6 afrkalaevekatkikedkiga..vivkdkkviargsnekelnakataHa 53 + r a++ ++ a +++++ iga v+ + k+v+a++ + + ++++Ha tr|A7SKU7|A7SKU7_NEMVE 138 YVRFAQQAAQYAKSKQQVGIGAamVDPETKRVVAVACDLRH-HGHPLQHA 186 66677888888999999999997788899*****9987444.66677776 PP == domain 2 score: 31.0 bits; conditional E-value: 7.8e-11 MafB19-deam 75 lyvtlepCdmCagaivqaglkklvygagnpks.......lnkLkv.kekngrvelv 122 lyvt+epC mCa a+v ++++++ y +g+ s kL++ k+ n+++e++ tr|A7SKU7|A7SKU7_NEMVE 232 LYVTQEPCVMCAMALVHSRIRRVFYSCGD--SirgalgsKYKLHTqKALNHHFEVF 285 8***************************4..4346766633333314457776665 PP >> tr|A7SK40|A7SK40_NEMVE Predicted protein (Fragment) OS=Nematostella vectensis OX=45351 GN=v1g57497 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.8 0.4 0.0024 7.2 72 86 .. 12 26 .. 5 32 .. 0.86 2 ? 5.1 0.6 0.0076 23 72 86 .. 36 50 .. 32 55 .. 0.85 3 ? 6.1 0.4 0.004 12 73 86 .. 62 75 .. 57 81 .. 0.84 4 ? 5.3 0.9 0.0068 21 72 86 .. 73 87 .. 65 93 .. 0.83 Alignments for each domain: == domain 1 score: 6.8 bits; conditional E-value: 0.0024 MafB19-deam 72 datlyvtlepCdmCa 86 ++tly+t+ p + C tr|A7SK40|A7SK40_NEMVE 12 GCTLYITHHPTPGCT 26 79************5 PP == domain 2 score: 5.1 bits; conditional E-value: 0.0076 MafB19-deam 72 datlyvtlepCdmCa 86 ++tly+t+ p + C tr|A7SK40|A7SK40_NEMVE 36 GCTLYITHYPTPGCT 50 69************5 PP == domain 3 score: 6.1 bits; conditional E-value: 0.004 MafB19-deam 73 atlyvtlepCdmCa 86 +tly+t+ p + C tr|A7SK40|A7SK40_NEMVE 62 CTLYITHHPTPGCT 75 9************5 PP == domain 4 score: 5.3 bits; conditional E-value: 0.0068 MafB19-deam 72 datlyvtlepCdmCa 86 ++tly+t+ p + C tr|A7SK40|A7SK40_NEMVE 73 GCTLYITHYPTPGCT 87 79***********95 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (138 nodes) Target sequences: 24428 (8257945 residues searched) Passed MSV filter: 730 (0.0298837); expected 488.6 (0.02) Passed bias filter: 459 (0.0187899); expected 488.6 (0.02) Passed Vit filter: 33 (0.00135091); expected 24.4 (0.001) Passed Fwd filter: 9 (0.00036843); expected 0.2 (1e-05) Initial search space (Z): 24428 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.12u 0.01s 00:00:00.13 Elapsed: 00:00:00.05 # Mc/sec: 22791.93 // [ok]