# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/MafB19-deam.hmm.txt # target sequence database: proteomes/Pan_troglodytes.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: MafB19-deam [M=138] Accession: PF14437.5 Description: MafB19-like deaminase Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.7e-22 78.9 0.1 4.7e-22 78.6 0.1 1.1 1 tr|H2QTU8|H2QTU8_PANTR ADAT2 isoform 2 OS=Pan troglodyt 1.6e-14 54.2 0.0 1.9e-14 53.9 0.0 1.1 1 tr|K6ZVZ8|K6ZVZ8_PANTR DCTD isoform 7 OS=Pan troglodyte 3.1e-12 46.7 0.6 4.9e-05 23.5 0.1 2.6 2 tr|K7B8T4|K7B8T4_PANTR CDADC1 isoform 1 OS=Pan troglody 0.0087 16.2 0.1 0.018 15.1 0.0 1.6 2 tr|H2R7B7|H2R7B7_PANTR APOBEC2 isoform 1 OS=Pan troglod ------ inclusion threshold ------ 0.14 12.3 0.1 0.24 11.5 0.1 1.3 1 tr|H2R235|H2R235_PANTR PSMD10 isoform 1 OS=Pan troglody 0.17 12.0 0.2 0.27 11.4 0.2 1.2 1 tr|A0A2I3T2F3|A0A2I3T2F3_PANTR Apolipoprotein B mRNA editing en Domain annotation for each sequence (and alignments): >> tr|H2QTU8|H2QTU8_PANTR ADAT2 isoform 2 OS=Pan troglodytes OX=9598 GN=ADAT2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 78.6 0.1 1.2e-25 4.7e-22 2 136 .. 21 173 .. 20 175 .. 0.87 Alignments for each domain: == domain 1 score: 78.6 bits; conditional E-value: 1.2e-25 MafB19-deam 2 dkekafrkalaevekatkikedkigavivkdkkviargsnekelnakataHaEiaalqqAakklkskrl......ddatlyvtlepC 82 + ek++++a+ ++++a++ +e+++g++ v +++v+++g ne ++ ++at HaE+ a+ q + ++ + + ++lyvt+epC tr|H2QTU8|H2QTU8_PANTR 21 ETEKWMEEAMHMAKEALENTEVPVGCLMVYNNEVVGKGRNEVNQTKNATRHAEMVAIDQVLDWCRQSGKspsevfEHTVLYVTVEPC 107 679******************************************************999876655543222222789********* PP MafB19-deam 83 dmCagaivqaglkklvygagnpks......lnkLkvkekngrvelv......eddckeilkgffkk 136 mCa a+ +++ +vyg++n+ + ln + +n+ + ++ e+lk f k+ tr|H2QTU8|H2QTU8_PANTR 108 IMCAAALRLMKIPLVVYGCQNERFggcgsvLNIASADLPNTGRPFQcipgyrAEEAVEMLKTFYKQ 173 ***********************99**999999999999999876688888866666888888776 PP >> tr|K6ZVZ8|K6ZVZ8_PANTR DCTD isoform 7 OS=Pan troglodytes OX=9598 GN=DCTD PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 53.9 0.0 5e-18 1.9e-14 3 103 .. 26 142 .. 24 177 .. 0.83 Alignments for each domain: == domain 1 score: 53.9 bits; conditional E-value: 5e-18 MafB19-deam 3 kekafrkalaevekatkikedkigaviv.kdkkviargsn...................ekelnakataHaEiaalqqAakklkskr 69 + ++f+ +++ +++k + ++ga iv ++k++++g+n + +++ HaE +a++ s+ tr|K6ZVZ8|K6ZVZ8_PANTR 26 WPEYFMAVAFLSAQRSKDPNSQVGACIVnSENKIVGIGYNgmpngcsddvlpwrrtaenKLDTKYPYVCHAELNAIMNK----NSTD 108 6789999999999999999999999666599***********************999655555566789*******975....4555 PP MafB19-deam 70 lddatlyvtlepCdmCagaivqaglkklvygagn 103 +++ +yv l pC+ Ca++i+qag+k++++ +++ tr|K6ZVZ8|K6ZVZ8_PANTR 109 VKGCSMYVALFPCNECAKLIIQAGIKEVIFMSDK 142 89***************************98873 PP >> tr|K7B8T4|K7B8T4_PANTR CDADC1 isoform 1 OS=Pan troglodytes OX=9598 GN=CDADC1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.5 0.1 1.3e-08 4.9e-05 65 106 .. 118 158 .. 72 193 .. 0.78 2 ! 21.1 0.0 7e-08 0.00027 49 101 .. 395 445 .. 322 469 .. 0.81 Alignments for each domain: == domain 1 score: 23.5 bits; conditional E-value: 1.3e-08 MafB19-deam 65 lkskrlddatlyvtlepCdmCagaivqaglkklvygagnpks 106 ++rl+++ ly ++pC+ C+++iv+ag+ ++ y ++p+ tr|K7B8T4|K7B8T4_PANTR 118 H-GSRLKNCDLYFSRKPCSACLKMIVNAGVNRISYWPADPEI 158 3.4679***************************998887764 PP == domain 2 score: 21.1 bits; conditional E-value: 7e-08 MafB19-deam 49 ataHaEiaalqqAakklkskrlddatlyvtlepCdmCagaivqaglkklvyga 101 HaE +al ++ +k ++ +++vt+ pCd C +i ag+k++ g tr|K7B8T4|K7B8T4_PANTR 395 YIIHAEQNALTFRCQEIKPE--ERSMIFVTKCPCDECVPLIKGAGIKQIYAGD 445 567**************999..9*************************98764 PP >> tr|H2R7B7|H2R7B7_PANTR APOBEC2 isoform 1 OS=Pan troglodytes OX=9598 GN=APOBEC2 PE=4 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.1 0.0 4.7e-06 0.018 42 91 .. 97 143 .. 67 156 .. 0.85 2 ? -3.9 0.0 3.5 1.4e+04 90 99 .. 168 177 .. 167 186 .. 0.62 Alignments for each domain: == domain 1 score: 15.1 bits; conditional E-value: 4.7e-06 MafB19-deam 42 ekelnakataHaEiaalqqAakklkskrlddatlyvtlepCdmCagaivq 91 e +++a aHaE a ++ ++ ++t yv pC Ca i++ tr|H2R7B7|H2R7B7_PANTR 97 E---DEHAAAHAEEAFFNTILPAFDPALRYNVTWYVSSSPCAACADRIIK 143 3...45899*****9999999999999999***************99997 PP == domain 2 score: -3.9 bits; conditional E-value: 3.5 MafB19-deam 90 vqaglkklvy 99 +qa+lkkl tr|H2R7B7|H2R7B7_PANTR 168 IQAALKKLKE 177 5666666644 PP >> tr|H2R235|H2R235_PANTR PSMD10 isoform 1 OS=Pan troglodytes OX=9598 GN=PSMD10 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 0.1 6.3e-05 0.24 15 68 .. 78 153 .. 72 163 .. 0.86 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 6.3e-05 MafB19-deam 15 ekatkikedkiga.vivkdkkviargsn.....................ekelnakataHaEiaalqqAakklksk 68 ++a++++ d i++ + k+ +v a+++n e n +a +H E+ a+ +Aa k+ k tr|H2R235|H2R235_PANTR 78 HIAASAGRDEIVKaLLGKGAQVNAVNQNgctplhyaasknrheiavmllEGGANPDAKDHYEATAMHRAAAKGNLK 153 56788888888884555999****************************9888999**************9998655 PP >> tr|A0A2I3T2F3|A0A2I3T2F3_PANTR Apolipoprotein B mRNA editing enzyme catalytic subunit 3H OS=Pan troglodytes OX=9598 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 0.2 6.9e-05 0.27 46 90 .. 48 93 .. 35 98 .. 0.79 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 6.9e-05 MafB19-deam 46 nakataHaEiaalqqAakkl.kskrlddatlyvtlepCdmCagaiv 90 ++k HaEi ++ + +++ ++t y t pC+ Ca +v tr|A0A2I3T2F3|A0A2I3T2F3_PANTR 48 ENKKKCHAEICFINEIKSMGlDETQCYQVTCYLTWSPCSSCAWKLV 93 567888****9999886554145667899************96665 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (138 nodes) Target sequences: 23008 (11942255 residues searched) Passed MSV filter: 665 (0.028903); expected 460.2 (0.02) Passed bias filter: 450 (0.0195584); expected 460.2 (0.02) Passed Vit filter: 41 (0.00178199); expected 23.0 (0.001) Passed Fwd filter: 6 (0.000260779); expected 0.2 (1e-05) Initial search space (Z): 23008 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.13u 0.01s 00:00:00.14 Elapsed: 00:00:00.08 # Mc/sec: 20600.39 // [ok]