# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/MafB19-deam.hmm.txt # target sequence database: proteomes/Tetrahymena_thermophila.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: MafB19-deam [M=138] Accession: PF14437.5 Description: MafB19-like deaminase Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.7e-19 68.2 0.4 1.1e-18 67.9 0.4 1.1 1 tr|A4VDC3|A4VDC3_TETTS Cytidine and deoxycytidylate deaminas 1.3e-15 57.9 1.0 2.1e-15 57.3 1.0 1.2 1 tr|I7M9H8|I7M9H8_TETTS Cytidine and deoxycytidylate deaminas 2.4e-14 53.8 0.1 7.9e-14 52.1 0.1 1.9 1 tr|I7MN23|I7MN23_TETTS Cytidine and deoxycytidylate deaminas 2.7e-05 24.5 2.6 5e-05 23.6 0.3 2.4 2 tr|Q22TJ9|Q22TJ9_TETTS Cytidine and deoxycytidylate deaminas Domain annotation for each sequence (and alignments): >> tr|A4VDC3|A4VDC3_TETTS Cytidine and deoxycytidylate deaminase zinc-binding region protein OS=Tetrahymena thermophila # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 67.9 0.4 1.6e-22 1.1e-18 1 100 [. 5 105 .. 5 126 .. 0.92 Alignments for each domain: == domain 1 score: 67.9 bits; conditional E-value: 1.6e-22 MafB19-deam 1 edkekafrkalaevekat.kikedkigavivkdkkviargsnekelnakataHaEiaalqqAakklkskrlddatlyvtlepCdmCa 86 +d++ + ++a++e+e a+ ++++ g+viv d+k+i r++n+ + ++taHaE a++ A+k+ ks l+d+++y +pC+mC tr|A4VDC3|A4VDC3_TETTS 5 NDHQYFIQEAIKEAELAViTGDGEPFGCVIVRDGKIIVRAHNRLYIDYDPTAHAETVAIRLACKQEKSLILKDCIIYASAQPCPMCS 91 5899999999****9986155789*************************************************************** PP MafB19-deam 87 gaivqaglkklvyg 100 ai g k++ y tr|A4VDC3|A4VDC3_TETTS 92 TAISACGAKEVYYC 105 ***99999999875 PP >> tr|I7M9H8|I7M9H8_TETTS Cytidine and deoxycytidylate deaminase zinc-binding region protein OS=Tetrahymena thermophila # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.3 1.0 3.1e-19 2.1e-15 6 135 .. 19 169 .. 15 171 .. 0.87 Alignments for each domain: == domain 1 score: 57.3 bits; conditional E-value: 3.1e-19 MafB19-deam 6 afrkalaevekatkikedkigavivk......dkkviargsnekelnakataHaEiaalqqAakklks.....krlddatlyvtlep 81 +++ a+++ ++at++ e+ +g+v vk d++++a+ +n++++ +at H Ei+ ++ +k ++ + ++ tl+vt ep tr|I7M9H8|I7M9H8_TETTS 19 YMKLAIEQSKIATDKLEVAVGCVMVKftnnnqDHEIVAQSHNKTNQYGNATLHCEINCINEILDKYGQnydeqQIFKQITLFVTCEP 105 89999*****************9874444444889***************************99998622111456789******** PP MafB19-deam 82 CdmCagaivqaglkklvygagnpks...lnkLkvkekngrvelv.......eddckeilkgffk 135 C mCa + g+k++ +g+ n+k+ + L++++ n + e++ck++lk+f + tr|I7M9H8|I7M9H8_TETTS 106 CIMCAYSLSLMGIKEVYFGCYNEKFggnGTILDLNTANYGANTYpsyggflEEECKQVLKQFYE 169 ***************************988899999998887668999************9976 PP >> tr|I7MN23|I7MN23_TETTS Cytidine and deoxycytidylate deaminase zinc-binding region protein OS=Tetrahymena thermophila # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 52.1 0.1 1.2e-17 7.9e-14 2 102 .. 203 325 .. 202 354 .. 0.87 Alignments for each domain: == domain 1 score: 52.1 bits; conditional E-value: 1.2e-17 MafB19-deam 2 dkekafrkalaevekatkikedkigaviv.kdkkviargsn.......................ekelnakataHaEiaalqqAakk 64 +++++f+ + ev+k+++++++ +ga+ + k+k+++ +g+n + l++ HaE + l tr|I7MN23|I7MN23_TETTS 203 SWDEYFMRLAVEVKKRSNCNKRSVGAILIsKEKRILSTGYNgtplrmkdcfyggcercnqntaqGQGLDQCWCIHAEENCLLDI--G 287 589***********************76669***************************9999887788999999******9988..5 PP MafB19-deam 65 lkskrlddatlyvtlepCdmCagaivqaglkklvygag 102 + ++++ + t+y+tl pC mCa++i+q+g+ ++vy + tr|I7MN23|I7MN23_TETTS 288 VRESKQFEPTMYTTLFPCRMCAKVIIQSGVTRIVYMED 325 66666789*************************99765 PP >> tr|Q22TJ9|Q22TJ9_TETTS Cytidine and deoxycytidylate deaminase zinc-binding region protein OS=Tetrahymena thermophila # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.2 0.7 0.17 1.1e+03 5 56 .. 136 189 .. 131 225 .. 0.66 2 ! 23.6 0.3 7.4e-09 5e-05 74 122 .. 276 333 .. 200 350 .. 0.82 Alignments for each domain: == domain 1 score: -0.2 bits; conditional E-value: 0.17 MafB19-deam 5 kafrkalaevekatkikedkigaviv..kdkkviargsnekelnakataHaEia 56 +++r+ + ++++ ++++++ ++ i +kk++ + e+ ++++ +H ++ tr|Q22TJ9|Q22TJ9_TETTS 136 QVMRQCIDQAKQTYEKNNKFNACAIYdpIKKKILQFAVDETCRKQNSIKHCTMN 189 678888888888888888777775543456777777777777777777777663 PP == domain 2 score: 23.6 bits; conditional E-value: 7.4e-09 MafB19-deam 74 tlyvtlepCdmCagaivqaglkklvygagnpks.........lnkLkvkekngrvelv 122 +++ +epC mC a++ ++++++ y ++npk l ++ n+ + ++ tr|Q22TJ9|Q22TJ9_TETTS 276 DIFIVQEPCIMCSMALIHSRVRRVYYSLKNPKQeqfgglnedLMINHMDSLNHSFLVF 333 58999***************************99999987774444455667766555 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (138 nodes) Target sequences: 26971 (16912921 residues searched) Passed MSV filter: 2046 (0.0758593); expected 539.4 (0.02) Passed bias filter: 463 (0.0171666); expected 539.4 (0.02) Passed Vit filter: 44 (0.00163138); expected 27.0 (0.001) Passed Fwd filter: 4 (0.000148307); expected 0.3 (1e-05) Initial search space (Z): 26971 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.21u 0.01s 00:00:00.22 Elapsed: 00:00:00.10 # Mc/sec: 23339.83 // [ok]