# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/Met_10.hmm.txt
# target sequence database: proteomes/Ciona_intestinalis.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: Met_10 [M=199]
Accession: PF02475.15
Description: Met-10+ like-protein
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
1.4e-61 207.6 0.1 2.1e-61 207.0 0.1 1.2 1 sp|F7A355|TRM5_CIOIN tRNA (guanine(37)-N1)-methyltransfera
3e-59 200.0 0.1 4.4e-59 199.5 0.1 1.2 1 tr|I6L7H7|I6L7H7_CIOIN tRNA (guanine(37)-N1)-methyltransfera
1.1e-41 142.6 0.0 1.7e-41 142.0 0.0 1.2 1 tr|H2Y0C0|H2Y0C0_CIOIN Uncharacterized protein OS=Ciona inte
1.7e-07 31.1 0.0 1.1e-06 28.5 0.0 2.1 2 tr|F6SZY0|F6SZY0_CIOIN tRNA (guanine(26)-N(2))-dimethyltrans
1.6e-05 24.6 0.0 2.8e-05 23.8 0.0 1.4 1 tr|F6WB92|F6WB92_CIOIN methyltransferase-like protein 5 isof
7.9e-05 22.4 0.0 0.00013 21.7 0.0 1.3 1 tr|F6PXD8|F6PXD8_CIOIN Uncharacterized protein OS=Ciona inte
0.00051 19.7 0.1 0.00053 19.7 0.1 1.1 1 tr|L7N0T2|L7N0T2_CIOIN Uncharacterized protein OS=Ciona inte
0.001 18.7 0.0 0.0018 17.9 0.0 1.3 1 tr|F6X5I5|F6X5I5_CIOIN Uncharacterized protein OS=Ciona inte
0.0014 18.3 0.0 0.0026 17.4 0.0 1.4 1 tr|F6UKV2|F6UKV2_CIOIN Uncharacterized protein OS=Ciona inte
0.0031 17.2 0.0 0.0046 16.6 0.0 1.4 1 tr|F6XYB7|F6XYB7_CIOIN Methyltransferase-like protein OS=Cio
Domain annotation for each sequence (and alignments):
>> sp|F7A355|TRM5_CIOIN tRNA (guanine(37)-N1)-methyltransferase OS=Ciona intestinalis OX=7719 PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 207.0 0.1 1.3e-64 2.1e-61 2 187 .. 156 348 .. 155 359 .. 0.96
Alignments for each domain:
== domain 1 score: 207.0 bits; conditional E-value: 1.3e-64
EEEEETTEEEEEB-TTSSHHHHHHHHHHHHHS.S-SCEEEE-S-SBTTTTB--EEEEEES-.SEEEEEETTEEEEEETTTS---GGGHH CS
Met_10 2 kfeiiGdvvilnlreelkeykkvigevildkt.kvktvlrkvsevegefRtfelevlaGsdstetihkEngcrfklDvskvyfssklea 89
+f+++G+++++nlr++ +yk++ig+v+ldk +tv++k+++++ +fR+fe+ev+aG+++ +t E+g +f++D+skv+++s+l++
sp|F7A355|TRM5_CIOIN 156 GFSQVGHILHVNLRDHQLPYKHIIGQVLLDKIqTARTVVNKHQNIDNKFRNFEMEVIAGENNFVTRIIEHGRKFEFDFSKVFWNSRLST 244
799****************************999******************************************************* PP
HHHHHHTT--TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---TT-EE........ CS
Met_10 90 ErerlaklveegevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevireqlad........ 170
E++r+ + v+e +vV dvfAG+Gpfaipiak k+ v+a+dlnPes+++l +n++lNk + + +++Dgre+i+++l +
sp|F7A355|TRM5_CIOIN 245 EHQRITNFVSESDVVFDVFAGVGPFAIPIAK--KGCVVYANDLNPESYRWLLHNVALNKTKAKC--FNSDGREFIQTELRNylltrsph 329
*******************************..**************************98876..*********9999999******* PP
..EEEE--TTTGGGGHHHH CS
Met_10 171 ..rvvmnlpksaieFldkv 187
+v+mnlp+ a+eFld
sp|F7A355|TRM5_CIOIN 330 kvHVLMNLPAIAVEFLDVF 348
****************975 PP
>> tr|I6L7H7|I6L7H7_CIOIN tRNA (guanine(37)-N1)-methyltransferase OS=Ciona intestinalis OX=7719 PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 199.5 0.1 2.6e-62 4.4e-59 2 187 .. 172 367 .. 171 386 .. 0.95
Alignments for each domain:
== domain 1 score: 199.5 bits; conditional E-value: 2.6e-62
EEEEETTEEEEEB-TTSSHHHHHHH...HHHHHHS.S-SCEEEE-S-SBTTTTB--EEEEEES-.SEEEEEETTEEEEEETTTS--- CS
Met_10 2 kfeiiGdvvilnlreelkeykkvig...evildkt.kvktvlrkvsevegefRtfelevlaGsdstetihkEngcrfklDvskvyfs 84
+f+++G+++++nlr++ +yk++ig +v+ldk +tv++k+++++ +fR+fe+ev+aG+++ +t E+g +f++D+skv+++
tr|I6L7H7|I6L7H7_CIOIN 172 GFSQVGHILHVNLRDHQLPYKHIIGqqsQVLLDKIqTARTVVNKHQNIDNKFRNFEMEVIAGENNFVTRIIEHGRKFEFDFSKVFWN 258
799*********************8333599**9989************************************************** PP
GGGHHHHHHHHTT--TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---TT-EE. CS
Met_10 85 skleaErerlaklveegevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevireqlad. 170
s+l++E++r+ + v+e +vV dvfAG+Gpfaipiak k+ v+a+dlnPes+++l +n++lNk + + +++Dgre+i+++l +
tr|I6L7H7|I6L7H7_CIOIN 259 SRLSTEHQRITNFVSESDVVFDVFAGVGPFAIPIAK--KGCVVYANDLNPESYRWLLHNVALNKTKAKC--FNSDGREFIQTELRNy 341
************************************..**************************98876..*********9999999 PP
.........EEEE--TTTGGGGHHHH CS
Met_10 171 .........rvvmnlpksaieFldkv 187
+v+mnlp+ a+eFld
tr|I6L7H7|I6L7H7_CIOIN 342 lltrsphkvHVLMNLPAIAVEFLDVF 367
***********************975 PP
>> tr|H2Y0C0|H2Y0C0_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 142.0 0.0 1e-44 1.7e-41 2 198 .. 5 206 .. 4 209 .. 0.86
Alignments for each domain:
== domain 1 score: 142.0 bits; conditional E-value: 1e-44
EEEEETTEEEEEB-T.....TSSHHHHHHHHHHHHHSS-SCEEEE-S-SBTTTTB--EEEEEES-.SEEEEEETTEEEEEETTTS-- CS
Met_10 2 kfeiiGdvvilnlre.....elkeykkvigevildktkvktvlrkvsevegefRtfelevlaGsdstetihkEngcrfklDvskvyf 83
k+e+ Gd+v+l + ++ ++++ + +++ +v+ v ++++ +++ +R +++ +l G+d t + h +n + +k+D++k +f
tr|H2Y0C0|H2Y0C0_CIOIN 5 KWEKHGDLVMLPSNCfhlkvWAQLPQEQLWKYVAEALNVNRVAQQKNILNSDYRSPQVVMLLGDD-TWVTHIDNRIIYKFDITKSMF 90
6777777777754431000022333566777888999****************************.********************* PP
-GGGHHHHHHHHTT--TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---TT-EE CS
Met_10 84 sskleaErerlaklveegevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevireqlad 170
ss++++E+ r+a+l +ge+V+d+fAGiG+f++p+ ++ska++v a + nP+sv lk n+ lNkve++ k +++D+r v ++++ d
tr|H2Y0C0|H2Y0C0_CIOIN 91 SSGNITEKIRMANLNCDGEIVIDMFAGIGYFTLPLLVHSKARFVHACEWNPDSVTALKANLLLNKVESKCKIYEGDNRVVCPTEVGD 177
*************************************************************************************** PP
EEEE--TTTGG.GGHHHHHHHEEEEEEEE CS
Met_10 171 rvvmnlpksai.eFldkvlaalkdggvih 198
r++++l+ +a+ +++ + a +gg+ h
tr|H2Y0C0|H2Y0C0_CIOIN 178 RIILGLIPTAEqSYIAACKALKVKGGIFH 206
******99997257776666666665554 PP
>> tr|F6SZY0|F6SZY0_CIOIN tRNA (guanine(26)-N(2))-dimethyltransferase OS=Ciona intestinalis OX=7719 PE=3 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? -0.6 0.0 0.51 8.5e+02 137 156 .. 51 70 .. 36 89 .. 0.84
2 ! 28.5 0.0 6.5e-10 1.1e-06 95 198 .. 103 212 .. 75 213 .. 0.80
Alignments for each domain:
== domain 1 score: -0.6 bits; conditional E-value: 0.51
HHHHHHHHHHTT-TTCEEEE CS
Met_10 137 vkylkeniklNkvekvvkpi 156
+++ke +k Nk++ +k+
tr|F6SZY0|F6SZY0_CIOIN 51 TEFIKEKLKKNKINGEIKSS 70
58999********9999875 PP
== domain 2 score: 28.5 bits; conditional E-value: 6.5e-10
HTT--TT-EEEETT-TTTCCHHHCCHHT.TSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---.....TT-EEEEEE- CS
Met_10 95 aklveegevVvdvfAGiGpfaipiakys.kakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevir.....eqladrvvmn 175
++ eeg ++++ + G ++ ak kr++a+dl ++++++++nik N+v + v++ l+D+ +++ + +d + ++
tr|F6SZY0|F6SZY0_CIOIN 103 GEKYEEGVTILEALSATGLRSVRFAKELpGVKRIVANDLSHDAFQLIERNIKHNEVGHLVEANLGDATTFMYsnrgkLKEFDVIDID 189
456888999999999999999999985414579*************************************98554433445566677 PP
-TTTGGGGHHHHHHHEEEEEEEE CS
Met_10 176 lpksaieFldkvlaalkdggvih 198
sa Fld++++a+k gg+ +
tr|F6SZY0|F6SZY0_CIOIN 190 PYGSAACFLDAAVQAVKPGGLLC 212
77899************999887 PP
>> tr|F6WB92|F6WB92_CIOIN methyltransferase-like protein 5 isoform X4 OS=Ciona intestinalis OX=7719 GN=LOC100184601 PE=
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 23.8 0.0 1.7e-08 2.8e-05 101 180 .. 49 133 .. 43 160 .. 0.85
Alignments for each domain:
== domain 1 score: 23.8 bits; conditional E-value: 1.7e-08
T-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---......TT-EEEEEE--TTTG CS
Met_10 101 gevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevir......eqladrvvmnlpksa 180
g+ V+d+ G G ++i + ++ a+ l+id++ ++ + +++n + ++++vv+ i++D + + + + +d v+mn p +
tr|F6WB92|F6WB92_CIOIN 49 GKNVCDLGCGCGILSIGSSLLG-ANHCLGIDIDEDALEIFQSNCEAYELNNVVECIQADIARFSPsrnmilAKRFDTVLMNPPFGT 133
778**************99866.5569*********************************99988666666677889999987544 PP
>> tr|F6PXD8|F6PXD8_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 PE=4 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 21.7 0.0 7.7e-08 0.00013 101 179 .. 82 158 .. 58 191 .. 0.84
Alignments for each domain:
== domain 1 score: 21.7 bits; conditional E-value: 7.7e-08
T-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---TT-EEEEEE--TTT CS
Met_10 101 gevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevireqladrvvmnlpks 179
+v+vd f G G ai a ++vlaid++P + k+n + ve+++ i++ +++++ +ad v + p
tr|F6PXD8|F6PXD8_CIOIN 82 CDVIVDAFCGSGGNAIQFAF--TCEKVLAIDIDPVKLENAKHNAAIYGVEDRIDFICGSFFDIAPTLKADIVFLSPPWG 158
68*****************8..7778********************************999999999999877766655 PP
>> tr|L7N0T2|L7N0T2_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 19.7 0.1 3.2e-07 0.00053 99 157 .. 22 78 .. 7 80 .] 0.87
Alignments for each domain:
== domain 1 score: 19.7 bits; conditional E-value: 3.2e-07
-TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEE CS
Met_10 99 eegevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpil 157
g+vV+dv G G +++ +ak + a +v++i+ + v y k+ ++ Nk++++v+ i+
tr|L7N0T2|L7N0T2_CIOIN 22 FRGKVVLDVGCGTGVLSMFAAK-AGAAKVIGIECS-SIVDYAKKIVEANKLDHIVTLIK 78
5799******************.56666*****97.679***************98775 PP
>> tr|F6X5I5|F6X5I5_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 PE=3 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 17.9 0.0 1.1e-06 0.0018 100 175 .. 56 129 .. 39 151 .. 0.78
Alignments for each domain:
== domain 1 score: 17.9 bits; conditional E-value: 1.1e-06
TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---TT-EEEEEE- CS
Met_10 100 egevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevireqladrvvmn 175
+++vV+dv AG G ++ +a+ + ak+v+ai+ k k+ ++lN +++ + +++ ++ ++++d +v +
tr|F6X5I5|F6X5I5_CIOIN 56 KDKVVLDVGAGTGILSCFCAQ-AGAKKVYAIEASNI-AKQAKKVVELNGLSDQIVVMQCLLEDAFLPEKVDVIVSE 129
678*****************8.88999*****9865.577899*********998887766666667777766644 PP
>> tr|F6UKV2|F6UKV2_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 PE=3 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 17.4 0.0 1.6e-06 0.0026 102 165 .. 153 215 .. 132 302 .. 0.79
Alignments for each domain:
== domain 1 score: 17.4 bits; conditional E-value: 1.6e-06
-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG--- CS
Met_10 102 evVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevir 165
V+d+ G G +++ +a+ k +v+a ++ + +e i lN++++ +k+i++ ++++
tr|F6UKV2|F6UKV2_CIOIN 153 VHVLDIGSGTGLLSMMAAQ-LKSCTVYACEMSKAMHTISEECISLNQLSHQIKTINQHSEHISV 215
4699**************8.89999*******999999999***************99988764 PP
>> tr|F6XYB7|F6XYB7_CIOIN Methyltransferase-like protein OS=Ciona intestinalis OX=7719 GN=LOC100181090 PE=3 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 16.6 0.0 2.7e-06 0.0046 40 143 .. 28 126 .. 5 180 .. 0.79
Alignments for each domain:
== domain 1 score: 16.6 bits; conditional E-value: 2.7e-06
EE-S-SBTTTTB--EEEEEES-.SEEEEEETTEEEEEETTTS---GGGHHHHHHHHTT--TT-EEEETT-TTTCCHHHCCHHTTSSE CS
Met_10 40 rkvsevegefRtfelevlaGsdstetihkEngcrfklDvskvyfsskleaErerlaklveegevVvdvfAGiGpfaipiakyskakr 126
++++++ +efR ++lev a + k n ++f D + s+ E e+ ++ ++ v ++ G+G p+ +k+ +
tr|F6XYB7|F6XYB7_CIOIN 28 NQNKRLVTEFRSQKLEVEAKKM-WDLFYKRNTTNFFKD---RHWTSREFGEIEQRIHN-NQQTVLLEAGCGVGNAIFPLMAQAKDLF 109
5566666777777777766555.666677777777444...46888877776543332.34457778888999999999999***** PP
EEEEES-HHHHHHHHHH CS
Met_10 127 vlaidlnPesvkylken 143
v+a d P++v+++k+n
tr|F6XYB7|F6XYB7_CIOIN 110 VYACDFSPRAVELVKDN 126
**************998 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (199 nodes)
Target sequences: 16678 (5370518 residues searched)
Passed MSV filter: 480 (0.0287804); expected 333.6 (0.02)
Passed bias filter: 339 (0.0203262); expected 333.6 (0.02)
Passed Vit filter: 38 (0.00227845); expected 16.7 (0.001)
Passed Fwd filter: 10 (0.000599592); expected 0.2 (1e-05)
Initial search space (Z): 16678 [actual number of targets]
Domain search space (domZ): 10 [number of targets reported over threshold]
# CPU time: 0.11u 0.01s 00:00:00.12 Elapsed: 00:00:00.04
# Mc/sec: 26718.33
//
[ok]