# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/Met_10.hmm.txt # target sequence database: proteomes/Ciona_savignyi.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: Met_10 [M=199] Accession: PF02475.15 Description: Met-10+ like-protein Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.2e-61 206.5 0.1 4.6e-61 205.4 0.1 1.5 2 tr|H2Y5Z4|H2Y5Z4_CIOSA tRNA (guanine(37)-N1)-methyltransfera 6.2e-36 123.4 0.0 8.7e-36 122.9 0.0 1.2 1 tr|H2Y5Z0|H2Y5Z0_CIOSA Uncharacterized protein OS=Ciona savi 1e-06 28.0 0.0 6.5e-06 25.4 0.0 2.0 2 tr|H2ZLY0|H2ZLY0_CIOSA tRNA (guanine(26)-N(2))-dimethyltrans 4.1e-05 22.8 0.0 6.9e-05 22.1 0.0 1.3 1 tr|H2ZN24|H2ZN24_CIOSA Uncharacterized protein OS=Ciona savi 0.00014 21.1 0.0 0.00028 20.1 0.0 1.5 2 tr|H2ZQD2|H2ZQD2_CIOSA Uncharacterized protein OS=Ciona savi 0.0085 15.2 0.0 0.014 14.5 0.0 1.3 1 tr|H2YHG7|H2YHG7_CIOSA Uncharacterized protein OS=Ciona savi Domain annotation for each sequence (and alignments): >> tr|H2Y5Z4|H2Y5Z4_CIOSA tRNA (guanine(37)-N1)-methyltransferase OS=Ciona savignyi OX=51511 PE=3 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.8 0.0 2.9 5.7e+03 18 53 .. 58 93 .. 55 110 .. 0.77 2 ! 205.4 0.1 2.4e-64 4.6e-61 2 186 .. 154 346 .. 153 358 .. 0.96 Alignments for each domain: == domain 1 score: -3.8 bits; conditional E-value: 2.9 SSHHHHHHHHHHHHHSS-SCEEEE-S-SBTTTTB-- CS Met_10 18 lkeykkvigevildktkvktvlrkvsevegefRtfe 53 lk+++k+++ +++ t k v++ +++ ge R + tr|H2Y5Z4|H2Y5Z4_CIOSA 58 LKNFRKMMKSKLANLTINKKVIDPPTNLVGEGRSRG 93 678888888888888888888888888877777654 PP == domain 2 score: 205.4 bits; conditional E-value: 2.4e-64 EEEEETTEEEEEB-TTSSHHHHHHHHHHHHHS.S-SCEEEE-S-SBTTTTB--EEEEEES-.SEEEEEETTEEEEEETTTS---GGG CS Met_10 2 kfeiiGdvvilnlreelkeykkvigevildkt.kvktvlrkvsevegefRtfelevlaGsdstetihkEngcrfklDvskvyfsskl 87 +f+++G+++++nlr++ +yk++ig+v+ldk ktv++k+++++ efR+f++ev+aG+++++t E+g +f++D+skv+++s+l tr|H2Y5Z4|H2Y5Z4_CIOSA 154 GFSQVGHILHVNLRDHQLPYKQIIGQVLLDKIpTAKTVVNKHQNIDNEFRNFQMEVIAGDNNLVTRIIEHGRKFEFDFSKVFWNSRL 240 799*****************************9****************************************************** PP HHHHHHHHTT--TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---TT-EE.... CS Met_10 88 eaErerlaklveegevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevireqlad.... 170 ++E++r+ +l+ + +V dvfAG+Gpfaipiak k+ v+a+dlnP+s+k+l +n+klNk e v+ ++ Dgr++ir++l + tr|H2Y5Z4|H2Y5Z4_CIOSA 241 STEHQRITHLIPRDATVFDVFAGVGPFAIPIAK--KGCLVYANDLNPDSYKWLVHNVKLNKTE--VECFNCDGRDFIRDNLRNyilt 323 *********************************..**************************87..778**********99999**** PP .......EEEE--TTTGGGGHHH CS Met_10 171 .......rvvmnlpksaieFldk 186 +vvmnlp+ a+eFld tr|H2Y5Z4|H2Y5Z4_CIOSA 324 sktfhqvHVVMNLPAIAVEFLDV 346 *********************96 PP >> tr|H2Y5Z0|H2Y5Z0_CIOSA Uncharacterized protein OS=Ciona savignyi OX=51511 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 122.9 0.0 4.5e-39 8.7e-36 2 194 .. 29 224 .. 28 233 .. 0.85 Alignments for each domain: == domain 1 score: 122.9 bits; conditional E-value: 4.5e-39 EEEEETTEEEEEB-TTSSHHHHHH.....HHHHHHHSS-SCEEEE-S-SBTTTTB--EEEEEES-.SEEEEEETTEEEEEETTTS-- CS Met_10 2 kfeiiGdvvilnlreelkeykkvi.....gevildktkvktvlrkvsevegefRtfelevlaGsdstetihkEngcrfklDvskvyf 83 ++e+ Gd+++l + l e+ k++ e +++ + k + ++ + +R +++ +l G+d + h +n ++++++v+k +f tr|H2Y5Z0|H2Y5Z0_CIOSA 29 RWEKHGDLIVLPCDCFLAEFWKDLpqekfWECVAEGLHGKRIAKQGRISRNGYRSPQVSMLLGED-GWVTHVDNKIKYNFEVTKCMF 114 6888889999888888888755541111145666777778877776666999*************.8999***************** PP -GGGHHHHHHHHTT--TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---TT-EE CS Met_10 84 sskleaErerlaklveegevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevireqlad 170 s++++E+ r+akl + gevVvd+fAGiG+f++p+ +++ka++v a + nP++v l++ni+ Nkv+ + k + +D+r+v ++ +a+ tr|H2Y5Z0|H2Y5Z0_CIOSA 115 ASGNITEKIRMAKL-NAGEVVVDLFAGIGYFTLPLLVHAKAEFVHACEWNPDAVDALTRNIHDNKVHLKCKIYFGDNRTVCPHGVAN 200 ***********986.89********************************************************************** PP EEEE--TTTGGGGHHHHHHHEEEE CS Met_10 171 rvvmnlpksaieFldkvlaalkdg 194 rv+++l+ +a+ ++++alk tr|H2Y5Z0|H2Y5Z0_CIOSA 201 RVILGLIPTAQVSYATACKALKPT 224 ******999986666666666544 PP >> tr|H2ZLY0|H2ZLY0_CIOSA tRNA (guanine(26)-N(2))-dimethyltransferase OS=Ciona savignyi OX=51511 PE=3 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.4 0.0 3.4e-09 6.5e-06 101 198 .. 90 193 .. 84 194 .. 0.82 2 ? -0.3 0.0 0.26 5e+02 39 79 .. 476 516 .. 449 524 .. 0.82 Alignments for each domain: == domain 1 score: 25.4 bits; conditional E-value: 3.4e-09 T-EEEETT-TTTCCHHHCCHHT.TSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---.....TT-EEEEEE--TTTGG CS Met_10 101 gevVvdvfAGiGpfaipiakys.kakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevir.....eqladrvvmnlpksai 181 g ++++ + G ++ ak k+++a+dl ++++++k+ni N+v +vv++ ++D+ +++ ++ +d + ++ sa tr|H2ZLY0|H2ZLY0_CIOSA 90 GVRILEALSATGLRSVRFAKELpGVKQIVANDLSEDAFHLIKQNIDHNNVCDVVEANQGDATTYMYinrgkSKEFDVIDIDPYGSAA 176 555666666667777777764314578***********************************9986667767778888888899*** PP GGHHHHHHHEEEEEEEE CS Met_10 182 eFldkvlaalkdggvih 198 Fld++++a+k gg+ + tr|H2ZLY0|H2ZLY0_CIOSA 177 CFLDSAVQAVKPGGLLC 193 ***********999887 PP == domain 2 score: -0.3 bits; conditional E-value: 0.26 EEE-S-SBTTTTB--EEEEEES-.SEEEEEETTEEEEEETT CS Met_10 39 lrkvsevegefRtfelevlaGsdstetihkEngcrfklDvs 79 + vs+v+g +R ++l G++s k+ g+++ lD++ tr|H2ZLY0|H2ZLY0_CIOSA 476 ADSVSKVKGIVRFPNLPANWGPKSRAKSSKDGGIELSLDLK 516 4678999**************99999999999999999986 PP >> tr|H2ZN24|H2ZN24_CIOSA Uncharacterized protein OS=Ciona savignyi OX=51511 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.1 0.0 3.6e-08 6.9e-05 101 189 .. 99 186 .. 78 198 .. 0.87 Alignments for each domain: == domain 1 score: 22.1 bits; conditional E-value: 3.6e-08 T-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---TT-EEEEEE--TTTGGGGHHH. CS Met_10 101 gevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevireqladrvvmnlpksaieFldk. 186 +++vd f G G +i a +rv+aid++P + ++n + ve++++ i++ +++++ +ad + + p e++++ tr|H2ZN24|H2ZN24_CIOSA 99 CDIIVDAFCGSGGNSIQFAF--TCERVIAIDIDPVKLENARHNAAIYGVEDRIEFICGSFFDLAPTLKADVIFLSPPWGGPEYIHCd 183 589****************8..7788********************************************99999999999999986 PP HHH CS Met_10 187 vla 189 +++ tr|H2ZN24|H2ZN24_CIOSA 184 TYS 186 444 PP >> tr|H2ZQD2|H2ZQD2_CIOSA Uncharacterized protein OS=Ciona savignyi OX=51511 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 0.0 1.4e-07 0.00028 101 180 .. 49 133 .. 41 167 .. 0.84 2 ? -2.2 0.0 0.99 1.9e+03 59 84 .. 187 212 .. 155 214 .] 0.60 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 1.4e-07 T-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-G......GG---TT-EEEEEE--TTTG CS Met_10 101 gevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDg......revireqladrvvmnlpksa 180 g+ V+d+ G G ++i + ++ a+ l++d++ e+ + +n + ++e++v + +D+ r+v+r++++d v+mn p + tr|H2ZQD2|H2ZQD2_CIOSA 49 GKAVCDLGCGCGILSIGSSILG-ASYCLGVDIDKEALGIFLSNCEDYELESTVDCVHSDVvklascRNVLRKKQFDTVIMNPPFGT 133 789**************99865.6679******************************99633333367777**********88655 PP == domain 2 score: -2.2 bits; conditional E-value: 0.99 ES-.SEEEEEETTEEEEEETTTS--- CS Met_10 59 GsdstetihkEngcrfklDvskvyfs 84 d + hk ++ +++D+ + f+ tr|H2ZQD2|H2ZQD2_CIOSA 187 NLDASYKFHKKKSKDIEVDFIRFTFN 212 34444555666666777777766666 PP >> tr|H2YHG7|H2YHG7_CIOSA Uncharacterized protein OS=Ciona savignyi OX=51511 PE=3 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.5 0.0 7.3e-06 0.014 100 173 .. 73 144 .. 17 167 .. 0.78 Alignments for each domain: == domain 1 score: 14.5 bits; conditional E-value: 7.3e-06 TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---TT-EEEEE CS Met_10 100 egevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevireqladrvv 173 +++vV+dv AG G ++ +a+ + a++v+ai+ + + k+ ++ N ++++v +++ ++ ++++d +v tr|H2YHG7|H2YHG7_CIOSA 73 KDKVVLDVGAGTGILSCFCAQ-AGARKVYAIEASNIA-EQAKKVVETNGLSERVVVMQCILEDAFLPEKVDIIV 144 578*****************8.89999*****87655.557888888988888876665555554555555555 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (199 nodes) Target sequences: 11592 (4231397 residues searched) Passed MSV filter: 347 (0.0299344); expected 231.8 (0.02) Passed bias filter: 258 (0.0222567); expected 231.8 (0.02) Passed Vit filter: 23 (0.00198413); expected 11.6 (0.001) Passed Fwd filter: 6 (0.000517598); expected 0.1 (1e-05) Initial search space (Z): 11592 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.07u 0.00s 00:00:00.07 Elapsed: 00:00:00.03 # Mc/sec: 28068.27 // [ok]