# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/Met_10.hmm.txt
# target sequence database: proteomes/Drosophila_melanogaster.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: Met_10 [M=199]
Accession: PF02475.15
Description: Met-10+ like-protein
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
7e-61 205.1 0.0 1.1e-60 204.5 0.0 1.3 1 sp|Q8IRE4|TRM5_DROME tRNA (guanine(37)-N1)-methyltransfera
1.1e-05 24.9 0.0 1.6e-05 24.4 0.0 1.2 1 tr|Q8SX32|Q8SX32_DROME Arginine methyltransferase 8 OS=Droso
1.5e-05 24.5 0.0 8.7e-05 22.0 0.0 2.0 2 sp|Q9VK89|TRM1_DROME Probable tRNA (guanine(26)-N(2))-dime
0.00034 20.0 0.0 0.00051 19.5 0.0 1.3 1 sp|Q9VH48|CARM1_DROME Probable histone-arginine methyltrans
0.00074 18.9 0.0 0.0012 18.2 0.0 1.4 1 tr|Q9VEA4|Q9VEA4_DROME Trimethylguanosine synthase 1 OS=Dros
0.0017 17.8 0.0 0.003 17.0 0.0 1.4 1 sp|Q9U6Y9|ANM5_DROME Protein arginine N-methyltransferase
0.0018 17.7 0.0 0.0024 17.3 0.0 1.3 1 sp|Q7K3B9|MET16_DROME U6 small nuclear RNA (adenine-(43)-N(
0.0046 16.4 0.0 0.015 14.7 0.0 1.7 1 tr|Q9VFB3|Q9VFB3_DROME Arginine methyltransferase 3, isoform
0.0049 16.3 0.0 0.0074 15.7 0.0 1.2 1 tr|Q8IQN1|Q8IQN1_DROME Uncharacterized protein, isoform B OS
------ inclusion threshold ------
0.014 14.7 0.0 0.027 13.9 0.0 1.5 1 tr|Q9VVV7|Q9VVV7_DROME Uncharacterized protein OS=Drosophila
0.017 14.5 0.1 0.029 13.8 0.1 1.3 1 tr|Q9VGW7|Q9VGW7_DROME Arginine methyltransferase 1 OS=Droso
Domain annotation for each sequence (and alignments):
>> sp|Q8IRE4|TRM5_DROME tRNA (guanine(37)-N1)-methyltransferase OS=Drosophila melanogaster OX=7227 GN=CG32281 PE=2 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 204.5 0.0 8.6e-64 1.1e-60 2 188 .. 150 351 .. 149 374 .. 0.95
Alignments for each domain:
== domain 1 score: 204.5 bits; conditional E-value: 8.6e-64
EEEEETTEEEEEB-TTSSHHHHHHHHHHHHHS.S-SCEEEE-S-SBTTTTB--EEEEEES-.SEEEEEETTEEEEEETTTS---GGGHH CS
Met_10 2 kfeiiGdvvilnlreelkeykkvigevildkt.kvktvlrkvsevegefRtfelevlaGsdstetihkEngcrfklDvskvyfssklea 89
++++iG++++lnlr++l +yk++ig+v+ dk +++tv++k s+++ ++R+f+le++ G+ + +++ kEng+ f++D+skvy++++l++
sp|Q8IRE4|TRM5_DROME 150 SYSRIGHIAHLNLRDHLLPYKQLIGQVLRDKLpNCRTVVNKASSIDNTYRNFQLELICGDPDYQVETKENGVPFEFDFSKVYWNPRLST 238
89*********************************************************999*************************** PP
HHHHHHTT--TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---TT-EE........ CS
Met_10 90 ErerlaklveegevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevireqlad........ 170
E+er++k+ + ++v dvfAG+Gpf+ip+ak k vla+dlnPes+++l++n k+Nk +k ++Dgr++i e+l +
sp|Q8IRE4|TRM5_DROME 239 EHERIVKMLKSDDVLYDVFAGVGPFSIPAAK--KRCHVLANDLNPESFRWLQHNAKRNKCLPNIKMSNKDGRQFIVEELREdllkrlct 325
*******************************..99****************************************977776799***** PP
........EEEE--TTTGGGGHHHHH CS
Met_10 171 ........rvvmnlpksaieFldkvl 188
++ mnlp+ a+eFld+
sp|Q8IRE4|TRM5_DROME 326 tdtttygiHITMNLPAMAVEFLDAFR 351
**********************9844 PP
>> tr|Q8SX32|Q8SX32_DROME Arginine methyltransferase 8 OS=Drosophila melanogaster OX=7227 GN=Art8 PE=1 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 24.4 0.0 1.3e-08 1.6e-05 101 172 .. 41 111 .. 32 173 .. 0.92
Alignments for each domain:
== domain 1 score: 24.4 bits; conditional E-value: 1.3e-08
T-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---TT-EEEE CS
Met_10 101 gevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevireqladrv 172
+++V+dv AG G ++ +ak + a+ v+a++ + k + i+ N + +vvk+i++ ++e++ + a++v
tr|Q8SX32|Q8SX32_DROME 41 DKIVMDVGAGTGILSAFCAK-AGARLVYAVEASNVATKVALDLIEDNGLTNVVKVIQSRVEEFVLPAEAEKV 111
679****************9.999***************************************997766654 PP
>> sp|Q9VK89|TRM1_DROME Probable tRNA (guanine(26)-N(2))-dimethyltransferase OS=Drosophila melanogaster OX=7227 GN=CG63
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? -0.7 0.1 0.61 7.6e+02 46 92 .. 17 62 .. 4 73 .. 0.81
2 ! 22.0 0.0 7e-08 8.7e-05 99 195 .. 98 200 .. 94 204 .. 0.82
Alignments for each domain:
== domain 1 score: -0.7 bits; conditional E-value: 0.61
BTTTTB--EEEEEES-.SEEEEEETTEEEEEETTTS---GGGHHHHH CS
Met_10 46 egefRtfelevlaGsdstetihkEngcrfklDvskvyfsskleaEre 92
e ++R+++ e++ G + ++E + + + +vy ++l++Er+
sp|Q9VK89|TRM1_DROME 17 ENVIRERNAEIVSGGNVFYNPVQEFNRDLSIAALNVY-RQRLTKERS 62
678999999*****99999999999999999999986.788888886 PP
== domain 2 score: 22.0 bits; conditional E-value: 7e-08
-TT-EEEETT-TTTCCHHHCCHH.TTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---.....TT-EEEEEE--TTTGG CS
Met_10 99 eegevVvdvfAGiGpfaipiaky.skakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevir.....eqladrvvmnlpksai 181
e+g ++++ +A G +i a+ + ++++a+dl ++v ++ ni+ Nkve+ ++p +D+ +++ e+ +d v ++
sp|Q9VK89|TRM1_DROME 98 EDGLRILEALAATGLRSIRYAQEiAGVRQIVANDLSRQAVASINTNIRHNKVEELIEPSHSDAMTLMYlstqpEKRFDAVDLDPYGCPN 186
67778889999999999988875156688**********************************99976655567777777777777778 PP
GGHHHHHHHEEEEE CS
Met_10 182 eFldkvlaalkdgg 195
Fld ++++l dgg
sp|Q9VK89|TRM1_DROME 187 RFLDGAMQCLVDGG 200
88888888887776 PP
>> sp|Q9VH48|CARM1_DROME Probable histone-arginine methyltransferase CARMER OS=Drosophila melanogaster OX=7227 GN=Art4
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 19.5 0.0 4e-07 0.00051 101 185 .. 180 265 .. 163 356 .. 0.86
Alignments for each domain:
== domain 1 score: 19.5 bits; conditional E-value: 4e-07
T-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---TT-EEEEE...E--TTTGGGGHH CS
Met_10 101 gevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevireqladrvv...mnlpksaieFld 185
+++V+dv AG G ++ + + + a +v+ai+ +y ++ ++ N+v++++++i + +e+ ++++d ++ m+++ + + l+
sp|Q9VH48|CARM1_DROME 180 DKIVLDVGAGSGILSFFAVQ-AGAAKVYAIEASN-MAQYAQQLVESNNVQHKISVIPGKIEEIELPEKVDVIIsepMGYMLYNERMLE 265
679*********99998776.66777*****975.569*************************9999999777555555555555554 PP
>> tr|Q9VEA4|Q9VEA4_DROME Trimethylguanosine synthase 1 OS=Drosophila melanogaster OX=7227 GN=Tgs1 PE=4 SV=3
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 18.2 0.0 9.8e-07 0.0012 101 167 .. 299 363 .. 283 443 .. 0.91
Alignments for each domain:
== domain 1 score: 18.2 bits; conditional E-value: 9.8e-07
T-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---TT CS
Met_10 101 gevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevireq 167
+v+vd f G G ai a rv+a+d++ e + k+n v+++++ i +D +++ ++
tr|Q9VEA4|Q9VEA4_DROME 299 CDVIVDAFCGCGGNAIQFAN--TCGRVIAVDIDAEKLAMAKHNAGIYGVAHKIEFIHADFLQFAAST 363
589****************9..8889*********************************99998754 PP
>> sp|Q9U6Y9|ANM5_DROME Protein arginine N-methyltransferase 5 OS=Drosophila melanogaster OX=7227 GN=csul PE=1 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 17.0 0.0 2.4e-06 0.003 110 176 .. 343 413 .. 311 461 .. 0.80
Alignments for each domain:
== domain 1 score: 17.0 bits; conditional E-value: 2.4e-06
TTTCCHHHC...CHH.TTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---TT-EEEEEE-- CS
Met_10 110 GiGpfaipi...aky.skakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevireqladrvvmnl 176
G Gp+a ++ a + +++r++ i++nP++++ l + +k +k v+ + +D r++ +++lad +v +l
sp|Q9U6Y9|ANM5_DROME 343 GRGPLARAVfnaAELtKRKVRLYIIEKNPNAIRTLSNMVKTLWADKDVHIFSKDMRDFSPPELADIMVSEL 413
4455554331112221367899*******************************************887665 PP
>> sp|Q7K3B9|MET16_DROME U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase OS=Drosophila melanogaster OX=7227
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 17.3 0.0 1.9e-06 0.0024 120 165 .. 125 170 .. 112 253 .. 0.83
Alignments for each domain:
== domain 1 score: 17.3 bits; conditional E-value: 1.9e-06
HHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES.-GGG--- CS
Met_10 120 kyskakrvlaidlnPesvkylkeniklNkvekvvkpile.Dgrevir 165
k ++ +la + P+ ++y ken+k+N++e+ ++++ + D+ ++ +
sp|Q7K3B9|MET16_DROME 125 K-KNGWHMLALESKPQNIEYAKENVKRNHMESLIEVYAQpDNTNIFK 170
3.4677899*************************9986536666654 PP
>> tr|Q9VFB3|Q9VFB3_DROME Arginine methyltransferase 3, isoform A OS=Drosophila melanogaster OX=7227 GN=Art3 PE=1 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 14.7 0.0 1.2e-05 0.015 97 181 .. 240 423 .. 221 435 .. 0.61
Alignments for each domain:
== domain 1 score: 14.7 bits; conditional E-value: 1.2e-05
T--TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---.TT-EE............ CS
Met_10 97 lveegevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevir.eqlad............ 170
v g++V+dv G G ++i ++k + a rv++id + + + i+ Nkve+v + i++ ++ e++ d
tr|Q9VFB3|Q9VFB3_DROME 240 AVVRGKTVLDVGCGTGILSIFASK-AGAARVVGIDNSDIVYTAM-DIIRKNKVENV-ELIKGRLEDTDLpETKYDiiisewmgyfll 323
37889******************9.66667****9766666555.679*****985.344444433332266666555555555555 PP
....................................................................................... CS
Met_10 171 ....................................................................................... 170
tr|Q9VFB3|Q9VFB3_DROME 324 yesmldsiiyarenhlnpngiilpsrctlsllgygddtlyadevefwsnvyevdmsdlrkqsieeplmqvvdaefmltepeqianfd 410
555555555555555555555555555555555555555555555555555555555555555555555555555555555555555 PP
..EEEE--TTTGG CS
Met_10 171 ..rvvmnlpksai 181
v mn+p+ ++
tr|Q9VFB3|Q9VFB3_DROME 411 imTVDMNYPNFTH 423
5545555555555 PP
>> tr|Q8IQN1|Q8IQN1_DROME Uncharacterized protein, isoform B OS=Drosophila melanogaster OX=7227 GN=Dmel\CG32152 PE=3 SV
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 15.7 0.0 5.9e-06 0.0074 80 192 .. 26 132 .. 18 144 .. 0.83
Alignments for each domain:
== domain 1 score: 15.7 bits; conditional E-value: 5.9e-06
TS---GGGHHHHHHHHTT--TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---T CS
Met_10 80 kvyfsskleaErerlaklveegevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevire 166
++yf + ++ ++ l+k + +++ + G G +a+ +a+ akrv+a+d + y + ++ N e v++++++ +++ +
tr|Q8IQN1|Q8IQN1_DROME 26 HMYFFQSVIHHQRHLIK----DRTILVLCCGTGTLALMAAQ-MGAKRVYAVDYS-KVTGYTTLVVRQNGYEGVITVMNGRMKDLKLP 106
55555555555555544....56789999***********9.55777*****97.67789999************************ PP
T-EEEEEE--TTTGGGGHHHHHHHEE CS
Met_10 167 qladrvvmnlpksaieFldkvlaalk 192
+++d ++ n + ++ + ++l++l+
tr|Q8IQN1|Q8IQN1_DROME 107 TKVDGIICNWMGYCLLYESEILEVLE 132
***********999988888877766 PP
>> tr|Q9VVV7|Q9VVV7_DROME Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=cg3808 PE=1 SV=3
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 13.9 0.0 2.1e-05 0.027 100 167 .. 415 479 .. 326 541 .. 0.81
Alignments for each domain:
== domain 1 score: 13.9 bits; conditional E-value: 2.1e-05
TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---TT CS
Met_10 100 egevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevireq 167
++ + +d+ G G +++ ak++ k+v+++++ P+++k + n + N +++ k +++ + ++i++
tr|Q9VVV7|Q9VVV7_DROME 415 KDTTMLDICCGTGTITLAFAKHC--KKVMGVEIVPDAIKDAEFNAEANGIKNA-KFFTGNADDFIKSM 479
456789***************55..578********************99886.47888888888654 PP
>> tr|Q9VGW7|Q9VGW7_DROME Arginine methyltransferase 1 OS=Drosophila melanogaster OX=7227 GN=Art1 PE=1 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 13.8 0.1 2.3e-05 0.029 98 165 .. 89 154 .. 74 192 .. 0.82
Alignments for each domain:
== domain 1 score: 13.8 bits; conditional E-value: 2.3e-05
--TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG--- CS
Met_10 98 veegevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevir 165
+g++V+dv G G +++ +ak + a +v+a+d + +++ ++ + N++++v++++++ +e+
tr|Q9VGW7|Q9VGW7_DROME 89 LFQGKTVLDVGCGTGILSMFAAK-AGAAQVIAVDCS-NIIEFARQVVIDNNLQDVITVVKGKIEEIEL 154
45799*****************9.66677*****96.789****************999998888765 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (199 nodes)
Target sequences: 13786 (7394964 residues searched)
Passed MSV filter: 399 (0.0289424); expected 275.7 (0.02)
Passed bias filter: 333 (0.0241549); expected 275.7 (0.02)
Passed Vit filter: 29 (0.00210358); expected 13.8 (0.001)
Passed Fwd filter: 11 (0.000797911); expected 0.1 (1e-05)
Initial search space (Z): 13786 [actual number of targets]
Domain search space (domZ): 11 [number of targets reported over threshold]
# CPU time: 0.14u 0.01s 00:00:00.15 Elapsed: 00:00:00.05
# Mc/sec: 29431.96
//
[ok]