# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/Met_10.hmm.txt
# target sequence database:        proteomes/Petromyzon_marinus.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       Met_10  [M=199]
Accession:   PF02475.15
Description: Met-10+ like-protein
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
    9.1e-06   25.2   0.0      2e-05   24.1   0.0    1.5  2  tr|S4RW71|S4RW71_PETMA  Protein arginine methyltransferase 2 
    6.6e-05   22.3   0.5    0.00013   21.4   0.1    1.6  2  tr|S4RHT4|S4RHT4_PETMA  tRNA (guanine(26)-N(2))-dimethyltrans
     0.0011   18.4   0.0     0.0014   18.0   0.0    1.1  1  tr|S4RY85|S4RY85_PETMA  Electron transfer flavoprotein subuni
     0.0031   16.9   0.0      0.064   12.6   0.0    2.2  2  tr|S4R4I3|S4R4I3_PETMA  Phosphoethanolamine methyltransferase
     0.0038   16.6   0.0     0.0064   15.9   0.0    1.3  1  tr|S4RYQ5|S4RYQ5_PETMA  NOP2 nucleolar protein homolog (yeast
     0.0038   16.6   0.0     0.0064   15.9   0.0    1.3  1  tr|S4RYQ4|S4RYQ4_PETMA  NOP2 nucleolar protein homolog (yeast
  ------ inclusion threshold ------
      0.015   14.6   0.0      0.027   13.8   0.0    1.3  1  tr|S4RTT3|S4RTT3_PETMA  tRNA methyltransferase 11 homolog (S.
      0.035   13.5   0.0      0.056   12.8   0.0    1.2  1  tr|S4RQZ8|S4RQZ8_PETMA  THUMP domain containing 2 OS=Petromyz
      0.093   12.1   0.0       0.14   11.5   0.0    1.2  1  tr|S4RFW7|S4RFW7_PETMA  Coactivator-associated arginine methy


Domain annotation for each sequence (and alignments):
>> tr|S4RW71|S4RW71_PETMA  Protein arginine methyltransferase 2 OS=Petromyzon marinus OX=7757 PE=3 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.1   0.0   1.3e-08     2e-05     100     183 ..     134     216 ..     100     237 .. 0.87
   2 ?   -3.5   0.0       3.8   5.7e+03      69      84 ..     299     314 ..     298     320 .. 0.80

  Alignments for each domain:
  == domain 1  score: 24.1 bits;  conditional E-value: 1.3e-08
                             TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---TT-EEEEEE--TTTGGGG CS
                  Met_10 100 egevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevireqladrvvmnlpksaieF 183
                              g+ V+dv  G G  ++ +ak+++++rv+a++   e  ++ ++ ++ N ++++v+++++ +++v  +  +d +v + + ++  F
  tr|S4RW71|S4RW71_PETMA 134 RGKAVLDVGCGSGIISMLCAKHAQPSRVYAVEAS-ELARLTEQVVRCNGMKDTVRVLQGRVEDVELPGSVDCLVSEWMGTCLLF 216
                             6899****************************86.77799*************************9999999998888777544 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 3.8
                             ETTEEEEEETTTS--- CS
                  Met_10  69 EngcrfklDvskvyfs 84 
                             E  c ++lD+skv  s
  tr|S4RW71|S4RW71_PETMA 299 EPCCILQLDMSKVQTS 314
                             6679999****99755 PP

>> tr|S4RHT4|S4RHT4_PETMA  tRNA (guanine(26)-N(2))-dimethyltransferase OS=Petromyzon marinus OX=7757 PE=3 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.4   0.1   8.6e-08   0.00013      95     198 ..     136     245 ..     122     246 .. 0.83
   2 ?   -3.9   0.0         5   7.5e+03     147     173 ..     394     417 ..     392     428 .. 0.63

  Alignments for each domain:
  == domain 1  score: 21.4 bits;  conditional E-value: 8.6e-08
                             HTT--TT-EEEETT-TTTCCHHHCCHHTTS.SEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---.....TT-EEEEEE- CS
                  Met_10  95 aklveegevVvdvfAGiGpfaipiakyska.krvlaidlnPesvkylkeniklNkvekvvkpileDgrevir.....eqladrvvmn 175
                               ++eeg  V++ +A  G  +i  ak   + k ++++d   ++v  +++ni++N+v++ v++  +D+  ++      ++ +d v ++
  tr|S4RHT4|S4RHT4_PETMA 136 GVKCEEGVKVLEALAASGLRSIRFAKEIPGiKSIITNDFSKNAVAAINKNIEMNQVQHLVTASYSDASMLMYksknhKESFDVVDLD 222
                             34489999***************9996543378**********************************99987565545566677778 PP

                             -TTTGGGGHHHHHHHEEEEEEEE CS
                  Met_10 176 lpksaieFldkvlaalkdggvih 198
                                s ++Fld++++ +++gg+ +
  tr|S4RHT4|S4RHT4_PETMA 223 PYGSPVQFLDAAVQSVNEGGLLC 245
                             88899*************99987 PP

  == domain 2  score: -3.9 bits;  conditional E-value: 5
                             TT-TTCEEEEES-GGG---TT-EEEEE CS
                  Met_10 147 NkvekvvkpileDgrevireqladrvv 173
                             N v+k+++++++    +    + dr++
  tr|S4RHT4|S4RHT4_PETMA 394 NYVQKIISAVEANRTRFK---TSDRII 417
                             677777777777666664...445544 PP

>> tr|S4RY85|S4RY85_PETMA  Electron transfer flavoprotein subunit beta lysine methyltransferase OS=Petromyzon marinus OX
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.0   0.0   9.4e-07    0.0014      98     148 ..      67     117 ..      46     138 .. 0.78

  Alignments for each domain:
  == domain 1  score: 18.0 bits;  conditional E-value: 9.4e-07
                             --TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHH.HHHHHHTT CS
                  Met_10  98 veegevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkyl.keniklNk 148
                             v  g  V+d+  G G  ai++ak + a+ v+a+d++P +   +   +i lN 
  tr|S4RY85|S4RY85_PETMA  67 VVAGRAVLDLGSGCGAAAIAAAK-AGASLVVANDIDPGARPTVaAVAISLNA 117
                             667999****************9.88999********987544146677775 PP

>> tr|S4R4I3|S4R4I3_PETMA  Phosphoethanolamine methyltransferase OS=Petromyzon marinus OX=7757 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.6   0.0   4.2e-05     0.064     101     170 ..      51     116 ..      30     151 .. 0.85
   2 ?    1.8   0.0     0.087   1.3e+02      98     135 ..     281     317 ..     269     331 .. 0.80

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 4.2e-05
                             T-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---.TT-EE CS
                  Met_10 101 gevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevir.eqlad 170
                             +  V+++ AGiG f+  +ak  +a+ v a+d       +l +n +lN  +  +k +++D+ ++   e+ +d
  tr|S4R4I3|S4R4I3_PETMA  51 DAKVLELGAGIGRFTGHLAK--QARHVTAVDFM---QTFLDKNRELNSDHVNIKFLQADVTQLQFpENSFD 116
                             55799999************..99*******85...78*********************998865455555 PP

  == domain 2  score: 1.8 bits;  conditional E-value: 0.087
                             --TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HH CS
                  Met_10  98 veegevVvdvfAGiGpfaipiakyskakrvlaidlnPe 135
                              + g+ V+dv  GiG     +ak + ++ vl++dl  +
  tr|S4R4I3|S4R4I3_PETMA 281 LQAGQKVLDVGCGIGGGNFYMAK-AFKVDVLGMDLSSN 317
                             588***********998888888.66777999888665 PP

>> tr|S4RYQ5|S4RYQ5_PETMA  NOP2 nucleolar protein homolog (yeast) OS=Petromyzon marinus OX=7757 PE=3 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.9   0.0   4.2e-06    0.0064      98     185 ..     183     271 ..     177     288 .. 0.83

  Alignments for each domain:
  == domain 1  score: 15.9 bits;  conditional E-value: 4.2e-06
                             --TT-EEEETT-TTT.CCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---.TT-EEEEEE--TTTGGG CS
                  Met_10  98 veegevVvdvfAGiG.pfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevir.eqladrvvmnlpksaie 182
                              +e+e  +d+ A  G + + ++  + +   ++a+d+n e  k +  n+++  v + + + + Dgr +++  + +drv++++p s + 
  tr|S4RYQ5|S4RYQ5_PETMA 183 PQENEKLLDMCAAPGgKTSYAAQLMRNTGAIVANDVNSERLKSVVGNLHRLGVTNSI-VCNYDGRALAKvMSGFDRVLLDAPCSGTG 268
                             689*******99765255666666668899***************************.99*******9988899*****99987766 PP

                             GHH CS
                  Met_10 183 Fld 185
                              + 
  tr|S4RYQ5|S4RYQ5_PETMA 269 IIS 271
                             665 PP

>> tr|S4RYQ4|S4RYQ4_PETMA  NOP2 nucleolar protein homolog (yeast) OS=Petromyzon marinus OX=7757 PE=3 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.9   0.0   4.2e-06    0.0064      98     185 ..     192     280 ..     186     297 .. 0.83

  Alignments for each domain:
  == domain 1  score: 15.9 bits;  conditional E-value: 4.2e-06
                             --TT-EEEETT-TTT.CCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---.TT-EEEEEE--TTTGGG CS
                  Met_10  98 veegevVvdvfAGiG.pfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevir.eqladrvvmnlpksaie 182
                              +e+e  +d+ A  G + + ++  + +   ++a+d+n e  k +  n+++  v + + + + Dgr +++  + +drv++++p s + 
  tr|S4RYQ4|S4RYQ4_PETMA 192 PQENEKLLDMCAAPGgKTSYAAQLMRNTGAIVANDVNSERLKSVVGNLHRLGVTNSI-VCNYDGRALAKvMSGFDRVLLDAPCSGTG 277
                             689*******99765255666666668899***************************.99*******9988899*****99987766 PP

                             GHH CS
                  Met_10 183 Fld 185
                              + 
  tr|S4RYQ4|S4RYQ4_PETMA 278 IIS 280
                             665 PP

>> tr|S4RTT3|S4RTT3_PETMA  tRNA methyltransferase 11 homolog (S. cerevisiae) OS=Petromyzon marinus OX=7757 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.0   1.8e-05     0.027      97     148 ..     164     213 ..     158     224 .. 0.89

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 1.8e-05
                             T--TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT CS
                  Met_10  97 lveegevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNk 148
                              v++g +V+d f G G + +++a+   + +v++ d++ ++++ l ++ + N+
  tr|S4RTT3|S4RTT3_PETMA 164 RVQPGHLVCDPFVGTGSLLVACAR--FGAFVMGSDIDYNTIHGLGKASRKNQ 213
                             499*********************..66899*****9999998888887775 PP

>> tr|S4RQZ8|S4RQZ8_PETMA  THUMP domain containing 2 OS=Petromyzon marinus OX=7757 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.0   3.7e-05     0.056      98     162 ..     265     329 ..     254     354 .. 0.85

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 3.7e-05
                             --TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG CS
                  Met_10  98 veegevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgre 162
                             +++  vV+d + G+G + + +a   k +r l+ d++ +     keni+  ++++++  +++ +  
  tr|S4RQZ8|S4RQZ8_PETMA 265 IQPHAVVMDPMCGMGTLLLEAAMAWKTVRCLGTDVDAQQLAHAKENIHFAELDHRIGLLQASVTA 329
                             68999******************9****************************9999766665555 PP

>> tr|S4RFW7|S4RFW7_PETMA  Coactivator-associated arginine methyltransferase 1 OS=Petromyzon marinus OX=7757 PE=3 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.0   9.2e-05      0.14     101     179 ..     161     240 ..     148     326 .. 0.86

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 9.2e-05
                             T-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---TT-EEEEE...E--TTT CS
                  Met_10 101 gevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevireqladrvv...mnlpks 179
                             +++V+dv  G G ++  + + + a++v+a++    + +  +  ++ N++++++ +i + +++v  ++++d ++   m+++  
  tr|S4RFW7|S4RFW7_PETMA 161 DKIVLDVGCGSGILSFFAVQ-AGARKVYAVEASSMA-QHAEVLVRSNNLQDRIVVIPGKVEDVSIPDKVDVIIsepMGYMLF 240
                             5789********99987765.88999*****98776.567999********************9999999777555555544 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (199 nodes)
Target sequences:                        13539  (5048892 residues searched)
Passed MSV filter:                       269  (0.0198685); expected 270.8 (0.02)
Passed bias filter:                      213  (0.0157323); expected 270.8 (0.02)
Passed Vit filter:                        23  (0.0016988); expected 13.5 (0.001)
Passed Fwd filter:                         9  (0.000664746); expected 0.1 (1e-05)
Initial search space (Z):              13539  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.08u 0.00s 00:00:00.08 Elapsed: 00:00:00.04
# Mc/sec: 25118.24
//
[ok]