# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/Met_10.hmm.txt # target sequence database: proteomes/Petromyzon_marinus.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: Met_10 [M=199] Accession: PF02475.15 Description: Met-10+ like-protein Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 9.1e-06 25.2 0.0 2e-05 24.1 0.0 1.5 2 tr|S4RW71|S4RW71_PETMA Protein arginine methyltransferase 2 6.6e-05 22.3 0.5 0.00013 21.4 0.1 1.6 2 tr|S4RHT4|S4RHT4_PETMA tRNA (guanine(26)-N(2))-dimethyltrans 0.0011 18.4 0.0 0.0014 18.0 0.0 1.1 1 tr|S4RY85|S4RY85_PETMA Electron transfer flavoprotein subuni 0.0031 16.9 0.0 0.064 12.6 0.0 2.2 2 tr|S4R4I3|S4R4I3_PETMA Phosphoethanolamine methyltransferase 0.0038 16.6 0.0 0.0064 15.9 0.0 1.3 1 tr|S4RYQ5|S4RYQ5_PETMA NOP2 nucleolar protein homolog (yeast 0.0038 16.6 0.0 0.0064 15.9 0.0 1.3 1 tr|S4RYQ4|S4RYQ4_PETMA NOP2 nucleolar protein homolog (yeast ------ inclusion threshold ------ 0.015 14.6 0.0 0.027 13.8 0.0 1.3 1 tr|S4RTT3|S4RTT3_PETMA tRNA methyltransferase 11 homolog (S. 0.035 13.5 0.0 0.056 12.8 0.0 1.2 1 tr|S4RQZ8|S4RQZ8_PETMA THUMP domain containing 2 OS=Petromyz 0.093 12.1 0.0 0.14 11.5 0.0 1.2 1 tr|S4RFW7|S4RFW7_PETMA Coactivator-associated arginine methy Domain annotation for each sequence (and alignments): >> tr|S4RW71|S4RW71_PETMA Protein arginine methyltransferase 2 OS=Petromyzon marinus OX=7757 PE=3 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.1 0.0 1.3e-08 2e-05 100 183 .. 134 216 .. 100 237 .. 0.87 2 ? -3.5 0.0 3.8 5.7e+03 69 84 .. 299 314 .. 298 320 .. 0.80 Alignments for each domain: == domain 1 score: 24.1 bits; conditional E-value: 1.3e-08 TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---TT-EEEEEE--TTTGGGG CS Met_10 100 egevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevireqladrvvmnlpksaieF 183 g+ V+dv G G ++ +ak+++++rv+a++ e ++ ++ ++ N ++++v+++++ +++v + +d +v + + ++ F tr|S4RW71|S4RW71_PETMA 134 RGKAVLDVGCGSGIISMLCAKHAQPSRVYAVEAS-ELARLTEQVVRCNGMKDTVRVLQGRVEDVELPGSVDCLVSEWMGTCLLF 216 6899****************************86.77799*************************9999999998888777544 PP == domain 2 score: -3.5 bits; conditional E-value: 3.8 ETTEEEEEETTTS--- CS Met_10 69 EngcrfklDvskvyfs 84 E c ++lD+skv s tr|S4RW71|S4RW71_PETMA 299 EPCCILQLDMSKVQTS 314 6679999****99755 PP >> tr|S4RHT4|S4RHT4_PETMA tRNA (guanine(26)-N(2))-dimethyltransferase OS=Petromyzon marinus OX=7757 PE=3 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.4 0.1 8.6e-08 0.00013 95 198 .. 136 245 .. 122 246 .. 0.83 2 ? -3.9 0.0 5 7.5e+03 147 173 .. 394 417 .. 392 428 .. 0.63 Alignments for each domain: == domain 1 score: 21.4 bits; conditional E-value: 8.6e-08 HTT--TT-EEEETT-TTTCCHHHCCHHTTS.SEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---.....TT-EEEEEE- CS Met_10 95 aklveegevVvdvfAGiGpfaipiakyska.krvlaidlnPesvkylkeniklNkvekvvkpileDgrevir.....eqladrvvmn 175 ++eeg V++ +A G +i ak + k ++++d ++v +++ni++N+v++ v++ +D+ ++ ++ +d v ++ tr|S4RHT4|S4RHT4_PETMA 136 GVKCEEGVKVLEALAASGLRSIRFAKEIPGiKSIITNDFSKNAVAAINKNIEMNQVQHLVTASYSDASMLMYksknhKESFDVVDLD 222 34489999***************9996543378**********************************99987565545566677778 PP -TTTGGGGHHHHHHHEEEEEEEE CS Met_10 176 lpksaieFldkvlaalkdggvih 198 s ++Fld++++ +++gg+ + tr|S4RHT4|S4RHT4_PETMA 223 PYGSPVQFLDAAVQSVNEGGLLC 245 88899*************99987 PP == domain 2 score: -3.9 bits; conditional E-value: 5 TT-TTCEEEEES-GGG---TT-EEEEE CS Met_10 147 NkvekvvkpileDgrevireqladrvv 173 N v+k+++++++ + + dr++ tr|S4RHT4|S4RHT4_PETMA 394 NYVQKIISAVEANRTRFK---TSDRII 417 677777777777666664...445544 PP >> tr|S4RY85|S4RY85_PETMA Electron transfer flavoprotein subunit beta lysine methyltransferase OS=Petromyzon marinus OX # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.0 0.0 9.4e-07 0.0014 98 148 .. 67 117 .. 46 138 .. 0.78 Alignments for each domain: == domain 1 score: 18.0 bits; conditional E-value: 9.4e-07 --TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHH.HHHHHHTT CS Met_10 98 veegevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkyl.keniklNk 148 v g V+d+ G G ai++ak + a+ v+a+d++P + + +i lN tr|S4RY85|S4RY85_PETMA 67 VVAGRAVLDLGSGCGAAAIAAAK-AGASLVVANDIDPGARPTVaAVAISLNA 117 667999****************9.88999********987544146677775 PP >> tr|S4R4I3|S4R4I3_PETMA Phosphoethanolamine methyltransferase OS=Petromyzon marinus OX=7757 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.6 0.0 4.2e-05 0.064 101 170 .. 51 116 .. 30 151 .. 0.85 2 ? 1.8 0.0 0.087 1.3e+02 98 135 .. 281 317 .. 269 331 .. 0.80 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 4.2e-05 T-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---.TT-EE CS Met_10 101 gevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevir.eqlad 170 + V+++ AGiG f+ +ak +a+ v a+d +l +n +lN + +k +++D+ ++ e+ +d tr|S4R4I3|S4R4I3_PETMA 51 DAKVLELGAGIGRFTGHLAK--QARHVTAVDFM---QTFLDKNRELNSDHVNIKFLQADVTQLQFpENSFD 116 55799999************..99*******85...78*********************998865455555 PP == domain 2 score: 1.8 bits; conditional E-value: 0.087 --TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HH CS Met_10 98 veegevVvdvfAGiGpfaipiakyskakrvlaidlnPe 135 + g+ V+dv GiG +ak + ++ vl++dl + tr|S4R4I3|S4R4I3_PETMA 281 LQAGQKVLDVGCGIGGGNFYMAK-AFKVDVLGMDLSSN 317 588***********998888888.66777999888665 PP >> tr|S4RYQ5|S4RYQ5_PETMA NOP2 nucleolar protein homolog (yeast) OS=Petromyzon marinus OX=7757 PE=3 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.9 0.0 4.2e-06 0.0064 98 185 .. 183 271 .. 177 288 .. 0.83 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 4.2e-06 --TT-EEEETT-TTT.CCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---.TT-EEEEEE--TTTGGG CS Met_10 98 veegevVvdvfAGiG.pfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevir.eqladrvvmnlpksaie 182 +e+e +d+ A G + + ++ + + ++a+d+n e k + n+++ v + + + + Dgr +++ + +drv++++p s + tr|S4RYQ5|S4RYQ5_PETMA 183 PQENEKLLDMCAAPGgKTSYAAQLMRNTGAIVANDVNSERLKSVVGNLHRLGVTNSI-VCNYDGRALAKvMSGFDRVLLDAPCSGTG 268 689*******99765255666666668899***************************.99*******9988899*****99987766 PP GHH CS Met_10 183 Fld 185 + tr|S4RYQ5|S4RYQ5_PETMA 269 IIS 271 665 PP >> tr|S4RYQ4|S4RYQ4_PETMA NOP2 nucleolar protein homolog (yeast) OS=Petromyzon marinus OX=7757 PE=3 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.9 0.0 4.2e-06 0.0064 98 185 .. 192 280 .. 186 297 .. 0.83 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 4.2e-06 --TT-EEEETT-TTT.CCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---.TT-EEEEEE--TTTGGG CS Met_10 98 veegevVvdvfAGiG.pfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevir.eqladrvvmnlpksaie 182 +e+e +d+ A G + + ++ + + ++a+d+n e k + n+++ v + + + + Dgr +++ + +drv++++p s + tr|S4RYQ4|S4RYQ4_PETMA 192 PQENEKLLDMCAAPGgKTSYAAQLMRNTGAIVANDVNSERLKSVVGNLHRLGVTNSI-VCNYDGRALAKvMSGFDRVLLDAPCSGTG 277 689*******99765255666666668899***************************.99*******9988899*****99987766 PP GHH CS Met_10 183 Fld 185 + tr|S4RYQ4|S4RYQ4_PETMA 278 IIS 280 665 PP >> tr|S4RTT3|S4RTT3_PETMA tRNA methyltransferase 11 homolog (S. cerevisiae) OS=Petromyzon marinus OX=7757 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.8 0.0 1.8e-05 0.027 97 148 .. 164 213 .. 158 224 .. 0.89 Alignments for each domain: == domain 1 score: 13.8 bits; conditional E-value: 1.8e-05 T--TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT CS Met_10 97 lveegevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNk 148 v++g +V+d f G G + +++a+ + +v++ d++ ++++ l ++ + N+ tr|S4RTT3|S4RTT3_PETMA 164 RVQPGHLVCDPFVGTGSLLVACAR--FGAFVMGSDIDYNTIHGLGKASRKNQ 213 499*********************..66899*****9999998888887775 PP >> tr|S4RQZ8|S4RQZ8_PETMA THUMP domain containing 2 OS=Petromyzon marinus OX=7757 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.0 3.7e-05 0.056 98 162 .. 265 329 .. 254 354 .. 0.85 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 3.7e-05 --TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG CS Met_10 98 veegevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgre 162 +++ vV+d + G+G + + +a k +r l+ d++ + keni+ ++++++ +++ + tr|S4RQZ8|S4RQZ8_PETMA 265 IQPHAVVMDPMCGMGTLLLEAAMAWKTVRCLGTDVDAQQLAHAKENIHFAELDHRIGLLQASVTA 329 68999******************9****************************9999766665555 PP >> tr|S4RFW7|S4RFW7_PETMA Coactivator-associated arginine methyltransferase 1 OS=Petromyzon marinus OX=7757 PE=3 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 0.0 9.2e-05 0.14 101 179 .. 161 240 .. 148 326 .. 0.86 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 9.2e-05 T-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---TT-EEEEE...E--TTT CS Met_10 101 gevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevireqladrvv...mnlpks 179 +++V+dv G G ++ + + + a++v+a++ + + + ++ N++++++ +i + +++v ++++d ++ m+++ tr|S4RFW7|S4RFW7_PETMA 161 DKIVLDVGCGSGILSFFAVQ-AGARKVYAVEASSMA-QHAEVLVRSNNLQDRIVVIPGKVEDVSIPDKVDVIIsepMGYMLF 240 5789********99987765.88999*****98776.567999********************9999999777555555544 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (199 nodes) Target sequences: 13539 (5048892 residues searched) Passed MSV filter: 269 (0.0198685); expected 270.8 (0.02) Passed bias filter: 213 (0.0157323); expected 270.8 (0.02) Passed Vit filter: 23 (0.0016988); expected 13.5 (0.001) Passed Fwd filter: 9 (0.000664746); expected 0.1 (1e-05) Initial search space (Z): 13539 [actual number of targets] Domain search space (domZ): 9 [number of targets reported over threshold] # CPU time: 0.08u 0.00s 00:00:00.08 Elapsed: 00:00:00.04 # Mc/sec: 25118.24 // [ok]