# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/Met_10.hmm.txt # target sequence database: proteomes/Strongylocentrotus_purpuratus.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: Met_10 [M=199] Accession: PF02475.15 Description: Met-10+ like-protein Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-80 268.2 0.1 7.3e-60 202.8 0.0 2.2 2 tr|W4YER5|W4YER5_STRPU tRNA (guanine(37)-N1)-methyltransfera 1.1e-23 84.6 0.0 1.7e-23 84.1 0.0 1.2 1 tr|W4ZG91|W4ZG91_STRPU Uncharacterized protein OS=Strongyloc 8.2e-06 26.4 0.0 1.4e-05 25.6 0.0 1.3 1 tr|W4YDZ5|W4YDZ5_STRPU Uncharacterized protein OS=Strongyloc 4.8e-05 23.8 0.0 0.00013 22.5 0.0 1.6 1 tr|W4Y0S2|W4Y0S2_STRPU Uncharacterized protein OS=Strongyloc 0.00037 21.0 0.0 0.0008 19.9 0.0 1.6 2 tr|W4YIM5|W4YIM5_STRPU Uncharacterized protein OS=Strongyloc 0.0016 18.9 0.0 0.0025 18.2 0.0 1.2 1 tr|W4ZBP9|W4ZBP9_STRPU Uncharacterized protein OS=Strongyloc 0.0079 16.6 0.0 0.014 15.8 0.0 1.4 1 tr|W4YBQ4|W4YBQ4_STRPU Uncharacterized protein OS=Strongyloc ------ inclusion threshold ------ 0.064 13.7 0.0 0.12 12.8 0.0 1.4 1 tr|W4YG90|W4YG90_STRPU rRNA adenine N(6)-methyltransferase O 0.1 13.0 0.0 0.57 10.5 0.0 2.0 2 tr|W4YN62|W4YN62_STRPU tRNA (guanine(26)-N(2))-dimethyltrans 0.1 13.0 0.0 0.24 11.8 0.0 1.6 1 tr|W4YRX7|W4YRX7_STRPU Uncharacterized protein OS=Strongyloc 0.13 12.7 0.0 0.16 12.4 0.0 1.1 1 tr|W4YJI6|W4YJI6_STRPU Uncharacterized protein OS=Strongyloc 0.18 12.2 0.0 0.3 11.5 0.0 1.2 1 tr|W4XXY4|W4XXY4_STRPU Uncharacterized protein OS=Strongyloc Domain annotation for each sequence (and alignments): >> tr|W4YER5|W4YER5_STRPU tRNA (guanine(37)-N1)-methyltransferase OS=Strongylocentrotus purpuratus OX=7668 PE=3 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 202.8 0.0 3.1e-63 7.3e-60 2 186 .. 138 335 .. 137 358 .. 0.95 2 ! 63.3 0.0 1.7e-20 4.1e-17 108 187 .. 421 515 .. 416 535 .. 0.87 Alignments for each domain: == domain 1 score: 202.8 bits; conditional E-value: 3.1e-63 EEEEETTEEEEEB-TTSSHHHHHHHHHHHHHS.S-SCEEEE-S-SBTTTTB--EEEEEES-.SEEEEEETTEEEEEETTTS---GGG CS Met_10 2 kfeiiGdvvilnlreelkeykkvigevildkt.kvktvlrkvsevegefRtfelevlaGsdstetihkEngcrfklDvskvyfsskl 87 +f+++G++++lnlr+ e+kk+igev+l+kt +ktv++k +e++ ++R f++e +aG+ +t++ +kEn + + +D++kvy++++l tr|W4YER5|W4YER5_STRPU 138 GFSRVGHIMHLNLRQAQLEHKKLIGEVLLEKTpGIKTVVNKLNEIDNTYRFFNMECIAGEPDTVVTVKENHVAYSFDFAKVYWNPRL 224 79*********************************************************999************************* PP HHHHHHHHTT--TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---TT-EE.... CS Met_10 88 eaErerlaklveegevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevireqlad.... 170 ++E++r++++ ++ +vV d+fAG+Gpfaip+ak k+ +v a+dlnPes+++l+ n k Nk+++++k+ + Dgr+++ + ++ tr|W4YER5|W4YER5_STRPU 225 STEHQRIIEKLHPTDVVYDMFAGVGPFAIPAAK--KGCEVHANDLNPESFRWLEVNAKQNKLSSRLKASNLDGRQFAVD-IVKpdli 308 *********************************..*****************************************853.3334699 PP ...........EEEE--TTTGGGGHHH CS Met_10 171 ...........rvvmnlpksaieFldk 186 +++mnlp+ a+eFld tr|W4YER5|W4YER5_STRPU 309 tkakegfkykaHIIMNLPAIAVEFLDI 335 9************************96 PP == domain 2 score: 63.3 bits; conditional E-value: 1.7e-20 T-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---TT-EE...............EEEE--TTT CS Met_10 108 fAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevireqlad...............rvvmnlpks 179 G+Gpfa p+ak k+ +v a+dlnPes+++l+ n k Nk+++++k+ + Dgr+++ + + +++mnlp+ tr|W4YER5|W4YER5_STRPU 421 GGGVGPFATPAAK--KGCEVHANDLNPESFRWLELNAKQNKLSSRLKASNLDGRQFAVDVV-KpdliikakegfkykaHIIMNLPAI 504 57***********..*****************************************96433.3469********************* PP GGGGHHH...H CS Met_10 180 aieFldk...v 187 a+eFld + tr|W4YER5|W4YER5_STRPU 505 AVEFLDIfpsL 515 *****974443 PP >> tr|W4ZG91|W4ZG91_STRPU Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 84.1 0.0 7e-27 1.7e-23 82 177 .. 1 96 [. 1 119 [. 0.96 Alignments for each domain: == domain 1 score: 84.1 bits; conditional E-value: 7e-27 ---GGGHHHHHHHHTT--TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---TT- CS Met_10 82 yfsskleaErerlaklveegevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevireql 168 +fss++++E+ r+a+l +e+Vvd++AGiG+f++p +++kak ++a + nP++vk l+ n+klN v+++ +++D+r+v + + tr|W4ZG91|W4ZG91_STRPU 1 MFSSGNITEKLRIASLDCSNETVVDLYAGIGYFTLPYLVHAKAKLLYACEWNPHAVKALRTNLKLNGVNDRCIILEGDNRKVCPVGV 87 8************************************************************************************** PP EEEEEE--T CS Met_10 169 adrvvmnlp 177 adrv ++l+ tr|W4ZG91|W4ZG91_STRPU 88 ADRVNLGLI 96 ****88886 PP >> tr|W4YDZ5|W4YDZ5_STRPU Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=3 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.6 0.0 6e-09 1.4e-05 111 198 .. 52 144 .. 36 145 .. 0.78 Alignments for each domain: == domain 1 score: 25.6 bits; conditional E-value: 6e-09 TTCCHHHCCHHTTS.SEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---.TT-EE...EEEE--TTTGGGGHHHHHHHEE CS Met_10 111 iGpfaipiakyska.krvlaidlnPesvkylkeniklNkvekvvkpileDgrevir.eqlad...rvvmnlpksaieFldkvlaalk 192 G ++ iak + krv+a+d e+v+ +++ni+ N+ve+ v++ +D+ ++ + + d v ++ sa +Fld+ ++a++ tr|W4YDZ5|W4YDZ5_STRPU 52 SGLRSVRIAKEVPGiKRVVANDFSEEAVRDIERNIQFNNVEDLVEASHSDASLLMYkHRFKDsfnVVDLDPYGSAAQFLDSGVQAVR 138 56667777775433379**********************************99988544444331444666789************* PP EEEEEE CS Met_10 193 dggvih 198 +gg+ + tr|W4YDZ5|W4YDZ5_STRPU 139 NGGLLC 144 **9988 PP >> tr|W4Y0S2|W4Y0S2_STRPU Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.5 0.0 5.3e-08 0.00013 101 186 .. 1293 1376 .. 1279 1390 .. 0.86 Alignments for each domain: == domain 1 score: 22.5 bits; conditional E-value: 5.3e-08 T-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---TT-EEEEEE--TTTGGGGHH CS Met_10 101 gevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevireqladrvvmnlpksaieFld 185 +++vd f G G ai a +rv+a+d++P+ +++ ++n + ve++++ i +D +v+ +ad v + p ++l+ tr|W4Y0S2|W4Y0S2_STRPU 1293 CDLIVDAFCGSGGNAIQFAF--TCERVVAVDIDPAKIELARHNATVYGVEDRIEFIVGDFFKVADYLKADVVFLSPPWGGPKYLN 1375 5789***************8..7788*************************************9999999888877777777766 PP H CS Met_10 186 k 186 + tr|W4Y0S2|W4Y0S2_STRPU 1376 A 1376 5 PP >> tr|W4YIM5|W4YIM5_STRPU Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=3 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.9 0.0 3.3e-07 0.0008 96 175 .. 139 217 .. 109 269 .. 0.78 2 ? -3.9 0.0 6.6 1.6e+04 122 138 .. 306 322 .. 304 325 .. 0.77 Alignments for each domain: == domain 1 score: 19.9 bits; conditional E-value: 3.3e-07 TT--TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---TT-EEEEEE- CS Met_10 96 klveegevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevireqladrvvmn 175 k + +g+vV+dv G G +++ + ky+ akrv +i+ e + ++ i+ N+++++++ + + ++ + ++++d ++ + tr|W4YIM5|W4YIM5_STRPU 139 KEAMKGKVVLDVGCGTGILSMMCVKYGGAKRVHSIEAS-EMAETAEKLINHNNLSNKITLYHGKVEGTTLPEKVDLIISE 217 34678******************************986.55677899999999999999999888888777877766644 PP == domain 2 score: -3.9 bits; conditional E-value: 6.6 TTSSEEEEEES-HHHHH CS Met_10 122 skakrvlaidlnPesvk 138 +k++ v++ dln + k tr|W4YIM5|W4YIM5_STRPU 306 AKGEVVYSCDLNTVTLK 322 67889999999977665 PP >> tr|W4ZBP9|W4ZBP9_STRPU Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=3 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.2 0.0 1.1e-06 0.0025 101 182 .. 88 170 .. 72 189 .. 0.82 Alignments for each domain: == domain 1 score: 18.2 bits; conditional E-value: 1.1e-06 T-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---TT-EEEEE...E--TTTGGG CS Met_10 101 gevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevireqladrvv...mnlpksaie 182 ++vV+dv AG G ++ + + + a++v+ai+ + + k+ +k N++ +++++i + ++ev ++++d +v m+++ + tr|W4ZBP9|W4ZBP9_STRPU 88 DKVVLDVGAGSGILSFFAVQ-AGARKVYAIEASSIA-EQAKQLVKANNLGNRISVIAGKVEEVSIPEQVDLIVsepMGYMLFNER 170 689*********99987776.88999*****98766.568999********************9999999888555666555554 PP >> tr|W4YBQ4|W4YBQ4_STRPU Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=3 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.8 0.0 5.9e-06 0.014 99 153 .. 515 567 .. 451 613 .. 0.89 Alignments for each domain: == domain 1 score: 15.8 bits; conditional E-value: 5.9e-06 -TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCE CS Met_10 99 eegevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvv 153 + + +d+ G G i++ak + ++v+++++n ++++ ken + N v++v tr|W4YBQ4|W4YBQ4_STRPU 515 TKITTLLDICCGTGTIGISLAK--RVEKVIGVEMNEQAIEDAKENAAINGVDNVT 567 5556789***************..999************************9875 PP >> tr|W4YG90|W4YG90_STRPU rRNA adenine N(6)-methyltransferase OS=Strongylocentrotus purpuratus OX=7668 PE=3 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.0 5e-05 0.12 98 178 .. 41 118 .. 25 130 .. 0.84 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 5e-05 --TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---TT-EEEEEE--TT CS Met_10 98 veegevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevireqladrvvmnlpk 178 + ++V++v G G ++ + kak+v+a +l+P+ v l++ ++ + ++++i +D+ + ++d v nlp+ tr|W4YG90|W4YG90_STRPU 41 LRSTDTVLEVGPGTGNMTVKMLD--KAKKVVACELDPRLVAELQKRVQGTPFAPKLQVIVGDVLKTD-LPFFDVCVANLPY 118 567799999*99***99999887..***********************9999999999999987764.5566666666665 PP >> tr|W4YN62|W4YN62_STRPU tRNA (guanine(26)-N(2))-dimethyltransferase OS=Strongylocentrotus purpuratus OX=7668 PE=3 SV= # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.5 0.0 0.00024 0.57 119 149 .. 11 41 .. 2 70 .. 0.86 2 ? -0.6 0.0 0.64 1.5e+03 151 196 .. 131 176 .. 125 178 .. 0.89 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 0.00024 CHHTTSSEEEEEES-HHHHHHHHHHHHHTT- CS Met_10 119 akyskakrvlaidlnPesvkylkeniklNkv 149 ++ ++++v d+nPesv+ +++n lN++ tr|W4YN62|W4YN62_STRPU 11 HHHHDDVEVTVSDINPESVRNMRRNCILNNL 41 568899**********************986 PP == domain 2 score: -0.6 bits; conditional E-value: 0.64 TCEEEEES-GGG---TT-EEEEEE--TTTGGGGHHHHHHHEEEEEE CS Met_10 151 kvvkpileDgrevireqladrvvmnlpksaieFldkvlaalkdggv 196 +v+ ++ D++ ++r+ ++d + ++ a+ F+d++++ + ++g+ tr|W4YN62|W4YN62_STRPU 131 GTVTLVCCDANLLMRQRFFDFIFLDPYGCATPFMDSAFSNISNNGI 176 67888999*****************************999888776 PP >> tr|W4YRX7|W4YRX7_STRPU Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.8 0.0 9.9e-05 0.24 94 151 .. 106 160 .. 96 169 .. 0.83 Alignments for each domain: == domain 1 score: 11.8 bits; conditional E-value: 9.9e-05 HHTT--TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TT CS Met_10 94 laklveegevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvek 151 +ak ++g+ +d f G a+ +a + ++rv+ai+ + +++l+e ++lNk+++ tr|W4YRX7|W4YRX7_STRPU 106 IAKAQSKGNCWCDQFS-TGTIAMGVA--ACGHRVVAIEPHLQNFQLLQESVALNKLDD 160 5666778888888886.476666666..58999**********************975 PP >> tr|W4YJI6|W4YJI6_STRPU Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.0 6.6e-05 0.16 100 134 .. 153 186 .. 126 188 .] 0.89 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 6.6e-05 TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-H CS Met_10 100 egevVvdvfAGiGpfaipiakyskakrvlaidlnP 134 +g V+dv G G ai++ + a+rvla+d++P tr|W4YJI6|W4YJI6_STRPU 153 KGRSVLDVGSGCGASAIAARM-AGASRVLANDIDP 186 6889*************9886.89999*******9 PP >> tr|W4XXY4|W4XXY4_STRPU Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 0.0 0.00013 0.3 7 77 .. 214 285 .. 211 288 .. 0.70 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 0.00013 TTEEEEEB-TTSSHHHHHHHHHHHHHS..S-SCEEEE-S-SBTTTTB--EEEEEES-.SEEEEEETTEEEEEE CS Met_10 7 Gdvvilnlreelkeykkvigevildkt..kvktvlrkvsevegefRtfelevlaGsdstetihkEngcrfklD 77 Gd+++ n +e+ + y+ + + k k ++ e g+ R e+++l+G+ds + E ++++++D tr|W4XXY4|W4XXY4_STRPU 214 GDMAHENAEED-ESYDDEFEMSFTSSKkgKKKHIIGAPVEQPGRRRAEEMKILYGKDSPAIHGMETAIQMQFD 285 66666555443.444444443333222247778887766669***************999999*********9 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (199 nodes) Target sequences: 28594 (14266044 residues searched) Passed MSV filter: 901 (0.0315101); expected 571.9 (0.02) Passed bias filter: 670 (0.0234315); expected 571.9 (0.02) Passed Vit filter: 75 (0.00262293); expected 28.6 (0.001) Passed Fwd filter: 12 (0.000419668); expected 0.3 (1e-05) Initial search space (Z): 28594 [actual number of targets] Domain search space (domZ): 12 [number of targets reported over threshold] # CPU time: 0.24u 0.01s 00:00:00.25 Elapsed: 00:00:00.09 # Mc/sec: 31543.81 // [ok]