# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/Met_10.hmm.txt
# target sequence database: proteomes/Strongylocentrotus_purpuratus.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: Met_10 [M=199]
Accession: PF02475.15
Description: Met-10+ like-protein
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
6.8e-80 268.2 0.1 7.3e-60 202.8 0.0 2.2 2 tr|W4YER5|W4YER5_STRPU tRNA (guanine(37)-N1)-methyltransfera
1.1e-23 84.6 0.0 1.7e-23 84.1 0.0 1.2 1 tr|W4ZG91|W4ZG91_STRPU Uncharacterized protein OS=Strongyloc
8.2e-06 26.4 0.0 1.4e-05 25.6 0.0 1.3 1 tr|W4YDZ5|W4YDZ5_STRPU Uncharacterized protein OS=Strongyloc
4.8e-05 23.8 0.0 0.00013 22.5 0.0 1.6 1 tr|W4Y0S2|W4Y0S2_STRPU Uncharacterized protein OS=Strongyloc
0.00037 21.0 0.0 0.0008 19.9 0.0 1.6 2 tr|W4YIM5|W4YIM5_STRPU Uncharacterized protein OS=Strongyloc
0.0016 18.9 0.0 0.0025 18.2 0.0 1.2 1 tr|W4ZBP9|W4ZBP9_STRPU Uncharacterized protein OS=Strongyloc
0.0079 16.6 0.0 0.014 15.8 0.0 1.4 1 tr|W4YBQ4|W4YBQ4_STRPU Uncharacterized protein OS=Strongyloc
------ inclusion threshold ------
0.064 13.7 0.0 0.12 12.8 0.0 1.4 1 tr|W4YG90|W4YG90_STRPU rRNA adenine N(6)-methyltransferase O
0.1 13.0 0.0 0.57 10.5 0.0 2.0 2 tr|W4YN62|W4YN62_STRPU tRNA (guanine(26)-N(2))-dimethyltrans
0.1 13.0 0.0 0.24 11.8 0.0 1.6 1 tr|W4YRX7|W4YRX7_STRPU Uncharacterized protein OS=Strongyloc
0.13 12.7 0.0 0.16 12.4 0.0 1.1 1 tr|W4YJI6|W4YJI6_STRPU Uncharacterized protein OS=Strongyloc
0.18 12.2 0.0 0.3 11.5 0.0 1.2 1 tr|W4XXY4|W4XXY4_STRPU Uncharacterized protein OS=Strongyloc
Domain annotation for each sequence (and alignments):
>> tr|W4YER5|W4YER5_STRPU tRNA (guanine(37)-N1)-methyltransferase OS=Strongylocentrotus purpuratus OX=7668 PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 202.8 0.0 3.1e-63 7.3e-60 2 186 .. 138 335 .. 137 358 .. 0.95
2 ! 63.3 0.0 1.7e-20 4.1e-17 108 187 .. 421 515 .. 416 535 .. 0.87
Alignments for each domain:
== domain 1 score: 202.8 bits; conditional E-value: 3.1e-63
EEEEETTEEEEEB-TTSSHHHHHHHHHHHHHS.S-SCEEEE-S-SBTTTTB--EEEEEES-.SEEEEEETTEEEEEETTTS---GGG CS
Met_10 2 kfeiiGdvvilnlreelkeykkvigevildkt.kvktvlrkvsevegefRtfelevlaGsdstetihkEngcrfklDvskvyfsskl 87
+f+++G++++lnlr+ e+kk+igev+l+kt +ktv++k +e++ ++R f++e +aG+ +t++ +kEn + + +D++kvy++++l
tr|W4YER5|W4YER5_STRPU 138 GFSRVGHIMHLNLRQAQLEHKKLIGEVLLEKTpGIKTVVNKLNEIDNTYRFFNMECIAGEPDTVVTVKENHVAYSFDFAKVYWNPRL 224
79*********************************************************999************************* PP
HHHHHHHHTT--TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---TT-EE.... CS
Met_10 88 eaErerlaklveegevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevireqlad.... 170
++E++r++++ ++ +vV d+fAG+Gpfaip+ak k+ +v a+dlnPes+++l+ n k Nk+++++k+ + Dgr+++ + ++
tr|W4YER5|W4YER5_STRPU 225 STEHQRIIEKLHPTDVVYDMFAGVGPFAIPAAK--KGCEVHANDLNPESFRWLEVNAKQNKLSSRLKASNLDGRQFAVD-IVKpdli 308
*********************************..*****************************************853.3334699 PP
...........EEEE--TTTGGGGHHH CS
Met_10 171 ...........rvvmnlpksaieFldk 186
+++mnlp+ a+eFld
tr|W4YER5|W4YER5_STRPU 309 tkakegfkykaHIIMNLPAIAVEFLDI 335
9************************96 PP
== domain 2 score: 63.3 bits; conditional E-value: 1.7e-20
T-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---TT-EE...............EEEE--TTT CS
Met_10 108 fAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevireqlad...............rvvmnlpks 179
G+Gpfa p+ak k+ +v a+dlnPes+++l+ n k Nk+++++k+ + Dgr+++ + + +++mnlp+
tr|W4YER5|W4YER5_STRPU 421 GGGVGPFATPAAK--KGCEVHANDLNPESFRWLELNAKQNKLSSRLKASNLDGRQFAVDVV-KpdliikakegfkykaHIIMNLPAI 504
57***********..*****************************************96433.3469********************* PP
GGGGHHH...H CS
Met_10 180 aieFldk...v 187
a+eFld +
tr|W4YER5|W4YER5_STRPU 505 AVEFLDIfpsL 515
*****974443 PP
>> tr|W4ZG91|W4ZG91_STRPU Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 84.1 0.0 7e-27 1.7e-23 82 177 .. 1 96 [. 1 119 [. 0.96
Alignments for each domain:
== domain 1 score: 84.1 bits; conditional E-value: 7e-27
---GGGHHHHHHHHTT--TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---TT- CS
Met_10 82 yfsskleaErerlaklveegevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevireql 168
+fss++++E+ r+a+l +e+Vvd++AGiG+f++p +++kak ++a + nP++vk l+ n+klN v+++ +++D+r+v + +
tr|W4ZG91|W4ZG91_STRPU 1 MFSSGNITEKLRIASLDCSNETVVDLYAGIGYFTLPYLVHAKAKLLYACEWNPHAVKALRTNLKLNGVNDRCIILEGDNRKVCPVGV 87
8************************************************************************************** PP
EEEEEE--T CS
Met_10 169 adrvvmnlp 177
adrv ++l+
tr|W4ZG91|W4ZG91_STRPU 88 ADRVNLGLI 96
****88886 PP
>> tr|W4YDZ5|W4YDZ5_STRPU Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 25.6 0.0 6e-09 1.4e-05 111 198 .. 52 144 .. 36 145 .. 0.78
Alignments for each domain:
== domain 1 score: 25.6 bits; conditional E-value: 6e-09
TTCCHHHCCHHTTS.SEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---.TT-EE...EEEE--TTTGGGGHHHHHHHEE CS
Met_10 111 iGpfaipiakyska.krvlaidlnPesvkylkeniklNkvekvvkpileDgrevir.eqlad...rvvmnlpksaieFldkvlaalk 192
G ++ iak + krv+a+d e+v+ +++ni+ N+ve+ v++ +D+ ++ + + d v ++ sa +Fld+ ++a++
tr|W4YDZ5|W4YDZ5_STRPU 52 SGLRSVRIAKEVPGiKRVVANDFSEEAVRDIERNIQFNNVEDLVEASHSDASLLMYkHRFKDsfnVVDLDPYGSAAQFLDSGVQAVR 138
56667777775433379**********************************99988544444331444666789************* PP
EEEEEE CS
Met_10 193 dggvih 198
+gg+ +
tr|W4YDZ5|W4YDZ5_STRPU 139 NGGLLC 144
**9988 PP
>> tr|W4Y0S2|W4Y0S2_STRPU Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 22.5 0.0 5.3e-08 0.00013 101 186 .. 1293 1376 .. 1279 1390 .. 0.86
Alignments for each domain:
== domain 1 score: 22.5 bits; conditional E-value: 5.3e-08
T-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---TT-EEEEEE--TTTGGGGHH CS
Met_10 101 gevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevireqladrvvmnlpksaieFld 185
+++vd f G G ai a +rv+a+d++P+ +++ ++n + ve++++ i +D +v+ +ad v + p ++l+
tr|W4Y0S2|W4Y0S2_STRPU 1293 CDLIVDAFCGSGGNAIQFAF--TCERVVAVDIDPAKIELARHNATVYGVEDRIEFIVGDFFKVADYLKADVVFLSPPWGGPKYLN 1375
5789***************8..7788*************************************9999999888877777777766 PP
H CS
Met_10 186 k 186
+
tr|W4Y0S2|W4Y0S2_STRPU 1376 A 1376
5 PP
>> tr|W4YIM5|W4YIM5_STRPU Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 19.9 0.0 3.3e-07 0.0008 96 175 .. 139 217 .. 109 269 .. 0.78
2 ? -3.9 0.0 6.6 1.6e+04 122 138 .. 306 322 .. 304 325 .. 0.77
Alignments for each domain:
== domain 1 score: 19.9 bits; conditional E-value: 3.3e-07
TT--TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---TT-EEEEEE- CS
Met_10 96 klveegevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevireqladrvvmn 175
k + +g+vV+dv G G +++ + ky+ akrv +i+ e + ++ i+ N+++++++ + + ++ + ++++d ++ +
tr|W4YIM5|W4YIM5_STRPU 139 KEAMKGKVVLDVGCGTGILSMMCVKYGGAKRVHSIEAS-EMAETAEKLINHNNLSNKITLYHGKVEGTTLPEKVDLIISE 217
34678******************************986.55677899999999999999999888888777877766644 PP
== domain 2 score: -3.9 bits; conditional E-value: 6.6
TTSSEEEEEES-HHHHH CS
Met_10 122 skakrvlaidlnPesvk 138
+k++ v++ dln + k
tr|W4YIM5|W4YIM5_STRPU 306 AKGEVVYSCDLNTVTLK 322
67889999999977665 PP
>> tr|W4ZBP9|W4ZBP9_STRPU Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 18.2 0.0 1.1e-06 0.0025 101 182 .. 88 170 .. 72 189 .. 0.82
Alignments for each domain:
== domain 1 score: 18.2 bits; conditional E-value: 1.1e-06
T-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---TT-EEEEE...E--TTTGGG CS
Met_10 101 gevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevireqladrvv...mnlpksaie 182
++vV+dv AG G ++ + + + a++v+ai+ + + k+ +k N++ +++++i + ++ev ++++d +v m+++ +
tr|W4ZBP9|W4ZBP9_STRPU 88 DKVVLDVGAGSGILSFFAVQ-AGARKVYAIEASSIA-EQAKQLVKANNLGNRISVIAGKVEEVSIPEQVDLIVsepMGYMLFNER 170
689*********99987776.88999*****98766.568999********************9999999888555666555554 PP
>> tr|W4YBQ4|W4YBQ4_STRPU Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 15.8 0.0 5.9e-06 0.014 99 153 .. 515 567 .. 451 613 .. 0.89
Alignments for each domain:
== domain 1 score: 15.8 bits; conditional E-value: 5.9e-06
-TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCE CS
Met_10 99 eegevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvv 153
+ + +d+ G G i++ak + ++v+++++n ++++ ken + N v++v
tr|W4YBQ4|W4YBQ4_STRPU 515 TKITTLLDICCGTGTIGISLAK--RVEKVIGVEMNEQAIEDAKENAAINGVDNVT 567
5556789***************..999************************9875 PP
>> tr|W4YG90|W4YG90_STRPU rRNA adenine N(6)-methyltransferase OS=Strongylocentrotus purpuratus OX=7668 PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 12.8 0.0 5e-05 0.12 98 178 .. 41 118 .. 25 130 .. 0.84
Alignments for each domain:
== domain 1 score: 12.8 bits; conditional E-value: 5e-05
--TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---TT-EEEEEE--TT CS
Met_10 98 veegevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevireqladrvvmnlpk 178
+ ++V++v G G ++ + kak+v+a +l+P+ v l++ ++ + ++++i +D+ + ++d v nlp+
tr|W4YG90|W4YG90_STRPU 41 LRSTDTVLEVGPGTGNMTVKMLD--KAKKVVACELDPRLVAELQKRVQGTPFAPKLQVIVGDVLKTD-LPFFDVCVANLPY 118
567799999*99***99999887..***********************9999999999999987764.5566666666665 PP
>> tr|W4YN62|W4YN62_STRPU tRNA (guanine(26)-N(2))-dimethyltransferase OS=Strongylocentrotus purpuratus OX=7668 PE=3 SV=
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 10.5 0.0 0.00024 0.57 119 149 .. 11 41 .. 2 70 .. 0.86
2 ? -0.6 0.0 0.64 1.5e+03 151 196 .. 131 176 .. 125 178 .. 0.89
Alignments for each domain:
== domain 1 score: 10.5 bits; conditional E-value: 0.00024
CHHTTSSEEEEEES-HHHHHHHHHHHHHTT- CS
Met_10 119 akyskakrvlaidlnPesvkylkeniklNkv 149
++ ++++v d+nPesv+ +++n lN++
tr|W4YN62|W4YN62_STRPU 11 HHHHDDVEVTVSDINPESVRNMRRNCILNNL 41
568899**********************986 PP
== domain 2 score: -0.6 bits; conditional E-value: 0.64
TCEEEEES-GGG---TT-EEEEEE--TTTGGGGHHHHHHHEEEEEE CS
Met_10 151 kvvkpileDgrevireqladrvvmnlpksaieFldkvlaalkdggv 196
+v+ ++ D++ ++r+ ++d + ++ a+ F+d++++ + ++g+
tr|W4YN62|W4YN62_STRPU 131 GTVTLVCCDANLLMRQRFFDFIFLDPYGCATPFMDSAFSNISNNGI 176
67888999*****************************999888776 PP
>> tr|W4YRX7|W4YRX7_STRPU Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 11.8 0.0 9.9e-05 0.24 94 151 .. 106 160 .. 96 169 .. 0.83
Alignments for each domain:
== domain 1 score: 11.8 bits; conditional E-value: 9.9e-05
HHTT--TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TT CS
Met_10 94 laklveegevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvek 151
+ak ++g+ +d f G a+ +a + ++rv+ai+ + +++l+e ++lNk+++
tr|W4YRX7|W4YRX7_STRPU 106 IAKAQSKGNCWCDQFS-TGTIAMGVA--ACGHRVVAIEPHLQNFQLLQESVALNKLDD 160
5666778888888886.476666666..58999**********************975 PP
>> tr|W4YJI6|W4YJI6_STRPU Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 12.4 0.0 6.6e-05 0.16 100 134 .. 153 186 .. 126 188 .] 0.89
Alignments for each domain:
== domain 1 score: 12.4 bits; conditional E-value: 6.6e-05
TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-H CS
Met_10 100 egevVvdvfAGiGpfaipiakyskakrvlaidlnP 134
+g V+dv G G ai++ + a+rvla+d++P
tr|W4YJI6|W4YJI6_STRPU 153 KGRSVLDVGSGCGASAIAARM-AGASRVLANDIDP 186
6889*************9886.89999*******9 PP
>> tr|W4XXY4|W4XXY4_STRPU Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 11.5 0.0 0.00013 0.3 7 77 .. 214 285 .. 211 288 .. 0.70
Alignments for each domain:
== domain 1 score: 11.5 bits; conditional E-value: 0.00013
TTEEEEEB-TTSSHHHHHHHHHHHHHS..S-SCEEEE-S-SBTTTTB--EEEEEES-.SEEEEEETTEEEEEE CS
Met_10 7 Gdvvilnlreelkeykkvigevildkt..kvktvlrkvsevegefRtfelevlaGsdstetihkEngcrfklD 77
Gd+++ n +e+ + y+ + + k k ++ e g+ R e+++l+G+ds + E ++++++D
tr|W4XXY4|W4XXY4_STRPU 214 GDMAHENAEED-ESYDDEFEMSFTSSKkgKKKHIIGAPVEQPGRRRAEEMKILYGKDSPAIHGMETAIQMQFD 285
66666555443.444444443333222247778887766669***************999999*********9 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (199 nodes)
Target sequences: 28594 (14266044 residues searched)
Passed MSV filter: 901 (0.0315101); expected 571.9 (0.02)
Passed bias filter: 670 (0.0234315); expected 571.9 (0.02)
Passed Vit filter: 75 (0.00262293); expected 28.6 (0.001)
Passed Fwd filter: 12 (0.000419668); expected 0.3 (1e-05)
Initial search space (Z): 28594 [actual number of targets]
Domain search space (domZ): 12 [number of targets reported over threshold]
# CPU time: 0.24u 0.01s 00:00:00.25 Elapsed: 00:00:00.09
# Mc/sec: 31543.81
//
[ok]