# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/Met_10.hmm.txt
# target sequence database: proteomes/Trichomonas_vaginalis.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: Met_10 [M=199]
Accession: PF02475.15
Description: Met-10+ like-protein
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
2.9e-59 201.6 0.1 4.1e-59 201.2 0.1 1.2 1 sp|A2E5K9|TRM5_TRIVA tRNA (guanine(37)-N1)-methyltransfera
3.9e-09 38.0 0.1 6.2e-09 37.4 0.1 1.3 1 tr|A2FDH4|A2FDH4_TRIVA tRNA (guanine(26)-N(2))-dimethyltrans
6.2e-09 37.4 0.1 7.6e-09 37.1 0.1 1.1 1 tr|A2FGC5|A2FGC5_TRIVA Uncharacterized protein OS=Trichomona
3e-08 35.1 0.1 5.7e-08 34.2 0.1 1.4 1 tr|A2FQY9|A2FQY9_TRIVA tRNA (guanine(26)-N(2))-dimethyltrans
0.00013 23.3 0.0 0.00019 22.7 0.0 1.3 1 tr|A2ELU0|A2ELU0_TRIVA Uncharacterized protein OS=Trichomona
0.00014 23.2 0.0 0.00023 22.4 0.0 1.3 1 tr|A2DMU5|A2DMU5_TRIVA Methyltransferase, putative OS=Tricho
0.001 20.3 0.1 0.0015 19.8 0.1 1.2 1 tr|A2DME7|A2DME7_TRIVA Arginine N-methyltransferase, putativ
------ inclusion threshold ------
0.03 15.5 0.0 0.056 14.6 0.0 1.4 1 tr|A2F7I7|A2F7I7_TRIVA NOL1/NOP2/sun family putative RNA met
0.098 13.8 0.1 0.23 12.6 0.2 1.5 1 tr|A2FDN2|A2FDN2_TRIVA Methyltransferase, FkbM family protei
0.24 12.6 0.0 0.38 11.9 0.0 1.4 1 tr|A2DM16|A2DM16_TRIVA MGC80481 protein, putative OS=Trichom
0.27 12.4 0.1 0.43 11.7 0.1 1.4 1 tr|A2FYV2|A2FYV2_TRIVA Membrane protein, putative OS=Trichom
Domain annotation for each sequence (and alignments):
>> sp|A2E5K9|TRM5_TRIVA tRNA (guanine(37)-N1)-methyltransferase OS=Trichomonas vaginalis OX=5722 GN=TVAG_038970 PE=3 SV
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 201.2 0.1 8.9e-63 4.1e-59 1 194 [. 105 301 .. 105 313 .. 0.94
Alignments for each domain:
== domain 1 score: 201.2 bits; conditional E-value: 8.9e-63
SEEEEETTEEEEEB-TTSSHHHHHHHHHHHHHS.S-SCEEEE-S-SBTTTTB--EEEEEES-.SEEEEEETTEEEEEETTTS---GGGH CS
Met_10 1 tkfeiiGdvvilnlreelkeykkvigevildkt.kvktvlrkvsevegefRtfelevlaGsdstetihkEngcrfklDvskvyfsskle 88
t+fe+iG++++lnl++el +ykkvige i+ k+ +ktv k++ ++ ++R++elev+aG+++ +t++k +g +fk+D+skvy++s+l+
sp|A2E5K9|TRM5_TRIVA 105 TSFETIGHIAHLNLPDELLPYKKVIGECIILKNpCIKTVAIKQGPINNVYRNMELEVIAGKNDFITEVKQSGFTFKMDFSKVYWNSRLQ 193
58**************************99999899***************************************************** PP
HHHHHHHTT--TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---....TT-EEEEE CS
Met_10 89 aErerlaklveegevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevir....eqladrvv 173
E+ ++++++e+ +V+d + GiGpfa+ +ak k+ rv a+dlnP+s+ +lken k N v++ v+ +++D+re+ir + d +v
sp|A2E5K9|TRM5_TRIVA 194 YEHDSVVATFKENSLVCDAMCGIGPFAVRAAK--KGCRVRANDLNPDSYYWLKENCKINGVSENVECFNMDAREFIRkqfdNGGCDYIV 280
********************************..******************************************9444444467*** PP
E--TTTGGGGHHHHHHHEEEE CS
Met_10 174 mnlpksaieFldkvlaalkdg 194
mnlp +a+eFld++ + +k++
sp|A2E5K9|TRM5_TRIVA 281 MNLPGTAVEFLDAIGEGAKKN 301
*************98887765 PP
>> tr|A2FDH4|A2FDH4_TRIVA tRNA (guanine(26)-N(2))-dimethyltransferase OS=Trichomonas vaginalis OX=5722 GN=TVAG_353820 P
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 37.4 0.1 1.4e-12 6.2e-09 103 198 .. 63 161 .. 34 162 .. 0.84
Alignments for each domain:
== domain 1 score: 37.4 bits; conditional E-value: 1.4e-12
EEEETT-TTTCCHHHCCHH.TTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---TT-EEEEEE--..TTTGGGGHHH CS
Met_10 103 vVvdvfAGiGpfaipiaky.skakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevireqladrvvmnl..pksaieFldk 186
+ + fA G +i ak + k+++++dl+P +v+ +k+ni+ Nkv+++v++ ++D+r+ + e+ v++l ++a Fl++
tr|A2FDH4|A2FDH4_TRIVA 63 SIFEAFAASGLRSIRYAKEiTGIKEIISNDLDPGAVEIIKRNIAINKVSNIVTASQGDARDKMLEEENKYQVLDLdpYSTAAPFLEA 149
5677899999999999886144589************************************9987776666766532567899**** PP
HHHHEEEEEEEE CS
Met_10 187 vlaalkdggvih 198
+++a+++g++ +
tr|A2FDH4|A2FDH4_TRIVA 150 AVKAATNGALLC 161
*****9998877 PP
>> tr|A2FGC5|A2FGC5_TRIVA Uncharacterized protein OS=Trichomonas vaginalis OX=5722 GN=TVAG_309480 PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 37.1 0.1 1.7e-12 7.6e-09 100 198 .. 60 161 .. 39 162 .. 0.85
Alignments for each domain:
== domain 1 score: 37.1 bits; conditional E-value: 1.7e-12
TT-EEEETT-TTTCCHHHCCHH.TTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---TT-EEEEEE--..TTTGGGG CS
Met_10 100 egevVvdvfAGiGpfaipiaky.skakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevireqladrvvmnl..pksaieF 183
++ + + fA G +i ak s k+++a+dl+ ++v+ +k+ni Nkv++ v++ ++D+re + e+ + v++l ++a F
tr|A2FGC5|A2FGC5_TRIVA 60 DDISIFEAFAASGLRSIRYAKEvSGVKKIIANDLDQAAVEIIKRNILINKVSNLVTASQGDAREKMLENENQFQVLDLdpYSTAAPF 146
5556778899999999999986255679************************************9997777777766532578899* PP
HHHHHHHEEEEEEEE CS
Met_10 184 ldkvlaalkdggvih 198
l+ v++a++dg++ +
tr|A2FGC5|A2FGC5_TRIVA 147 LEGVVKAATDGALLC 161
**********99887 PP
>> tr|A2FQY9|A2FQY9_TRIVA tRNA (guanine(26)-N(2))-dimethyltransferase OS=Trichomonas vaginalis OX=5722 GN=TVAG_439220 P
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 34.2 0.1 1.3e-11 5.7e-08 76 198 .. 23 155 .. 3 156 .. 0.75
Alignments for each domain:
== domain 1 score: 34.2 bits; conditional E-value: 1.3e-11
EETTTS---GGGHHHHH..HHH.....TT--TT-EEEETT-TTTCCHHHCCHHTTS.SEEEEEES-HHHHHHHHHHHHHTT-TTCEE CS
Met_10 76 lDvskvyfsskleaEre..rla.....klveegevVvdvfAGiGpfaipiakyska.krvlaidlnPesvkylkeniklNkvekvvk 154
+D s+v++++ + r l+ + v++ + fA G +i a+ + + + a+d++ ++ + +ni+lNkv+++vk
tr|A2FQY9|A2FQY9_TRIVA 23 IDKSEVFYNPVQNFNRDitCLVlqaynNRVKKPTNLFEAFAATGLRSIRYAREVTGfNSITANDIDKNAGSIIDRNIQLNKVDNIVK 109
6777777776655555411233111112244445567899********99986655368**************************** PP
EEES-GGG---TT-EEEEEE--.TTTGGG.GHHHHHHHEEEEEEEE CS
Met_10 155 pileDgrevireqladrvvmnl.pksaie.Fldkvlaalkdggvih 198
+ l+D+++v+++++ + +++l p+s+++ Fld++++a+ dg++ +
tr|A2FQY9|A2FQY9_TRIVA 110 SSLGDANKVMNSHKGEYQIIDLdPYSTVSiFLDAAIHAAADGALLC 155
***********9999988887646666655*********9999887 PP
>> tr|A2ELU0|A2ELU0_TRIVA Uncharacterized protein OS=Trichomonas vaginalis OX=5722 GN=TVAG_151750 PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 22.7 0.0 4.1e-08 0.00019 72 159 .. 341 431 .. 280 480 .. 0.77
Alignments for each domain:
== domain 1 score: 22.7 bits; conditional E-value: 4.1e-08
EEEEEETTTS---GGGHHHHH....HHHTT..--TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTC CS
Met_10 72 crfklDvskvyfsskleaEre....rlakl..veegevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekv 152
+k+D+s + f + ++ e r+ +l v++ v +dv G G +++ak kak+v++id++ ++++ k+n + Nk+++
tr|A2ELU0|A2ELU0_TRIVA 341 RGLKFDISPMSFFQTNTPGAEilfsRVESLaeVDKSTVLIDVCCGTGVIGLSMAK--KAKKVIGIDIEKDAIEDAKKNATKNKIKNA 425
456677777766666654443111144333337788999****************..***************************875 PP
EEEEES- CS
Met_10 153 vkpileD 159
i +
tr|A2ELU0|A2ELU0_TRIVA 426 E-FIAAP 431
2.44444 PP
>> tr|A2DMU5|A2DMU5_TRIVA Methyltransferase, putative OS=Trichomonas vaginalis OX=5722 GN=TVAG_254280 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 22.4 0.0 5.1e-08 0.00023 100 178 .. 48 127 .. 43 149 .. 0.87
Alignments for each domain:
== domain 1 score: 22.4 bits; conditional E-value: 5.1e-08
TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTC..EEEEES-GGG---TT-EEEEEE--TT CS
Met_10 100 egevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekv..vkpileDgrevireqladrvvmnlpk 178
eg++V d+ G G ++i++ + ak+v + dl+P s++ k+n+ l + ++ + + D+ ++ eq++d vvmn p
tr|A2DMU5|A2DMU5_TRIVA 48 EGKIVADLGCGCGILSIACLV-MGAKEVHSFDLDPVSIEAAKRNLDLLEFDEPppIFFHECDVTKLGDEQKFDTVVMNPPF 127
799*****************9.56788**********************9986225556778888888**********875 PP
>> tr|A2DME7|A2DME7_TRIVA Arginine N-methyltransferase, putative OS=Trichomonas vaginalis OX=5722 GN=TVAG_045760 PE=3 S
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 19.8 0.1 3.3e-07 0.0015 101 176 .. 41 114 .. 25 153 .. 0.85
Alignments for each domain:
== domain 1 score: 19.8 bits; conditional E-value: 3.3e-07
T-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---TT-EEEEEE-- CS
Met_10 101 gevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevireqladrvvmnl 176
+++Vvdv AG G +++ +a+ + ak+v+ai+ + ++ ik N+ e++++ + + ++e++ ++++d ++ +
tr|A2DME7|A2DME7_TRIVA 41 DKIVVDVGAGTGILSLFAAQ-AGAKKVYAIECTE-IANIAEKIIKDNNFENIITIVRGRANEITLPEKVDIIISEW 114
579****************8.88999*****975.556889999**********9999999999999999877444 PP
>> tr|A2F7I7|A2F7I7_TRIVA NOL1/NOP2/sun family putative RNA methylase containing protein OS=Trichomonas vaginalis OX=57
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 14.6 0.0 1.2e-05 0.056 99 173 .. 221 296 .. 215 332 .. 0.84
Alignments for each domain:
== domain 1 score: 14.6 bits; conditional E-value: 1.2e-05
-TT-EEEETT-TTTCCHHHCCHHTTSS.EEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---.TT-EEEEE CS
Met_10 99 eegevVvdvfAGiGpfaipiakyskak.rvlaidlnPesvkylkeniklNkvekvvkpileDgrevir.eqladrvv 173
++g + +d+ A G + +a++ k++ ++a+d+n + + l ni++ v +++ +++ Dgr + + +d v+
tr|A2F7I7|A2F7I7_TRIVA 221 QPGMRTLDMCAAPGGKTTHMAQLMKNQgVIIANDINRTRAQALIANIHRLGVTNTI-VVNYDGRAFPTvMGGFDAVM 296
7888999999999999999888877652679*************************.9********87555555555 PP
>> tr|A2FDN2|A2FDN2_TRIVA Methyltransferase, FkbM family protein OS=Trichomonas vaginalis OX=5722 GN=TVAG_011250 PE=4 S
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 12.6 0.2 5.1e-05 0.23 117 162 .. 125 169 .. 109 238 .. 0.82
Alignments for each domain:
== domain 1 score: 12.6 bits; conditional E-value: 5.1e-05
HCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG CS
Met_10 117 piakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgre 162
+ y+k + v++ ++ + ++ +ke i lN+++++v pi + +
tr|A2FDN2|A2FDN2_TRIVA 125 ILQEYTK-RHVYSYEISKQVFEDMKETISLNNLQNKVIPIRKGISD 169
4555555.56*****************************9876555 PP
>> tr|A2DM16|A2DM16_TRIVA MGC80481 protein, putative OS=Trichomonas vaginalis OX=5722 GN=TVAG_463050 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 11.9 0.0 8.4e-05 0.38 100 174 .. 114 189 .. 107 238 .. 0.91
Alignments for each domain:
== domain 1 score: 11.9 bits; conditional E-value: 8.4e-05
TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---.TT-EEEEEE CS
Met_10 100 egevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevir.eqladrvvm 174
+ +++d G+G + + a ++++v++id + k+n k kv++ +++D+ ++++ ++ r+v
tr|A2DM16|A2DM16_TRIVA 114 DSSIIIDACCGVGGNTTAFAACIQDSFVIGIDTSAIRIVCAKKNSKVCKVDQATDFVKGDVIKFLNtQHNSARFVF 189
567899****************************999999************************987777777775 PP
>> tr|A2FYV2|A2FYV2_TRIVA Membrane protein, putative OS=Trichomonas vaginalis OX=5722 GN=TVAG_009340 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 11.7 0.1 9.5e-05 0.43 99 135 .. 66 101 .. 44 149 .. 0.83
Alignments for each domain:
== domain 1 score: 11.7 bits; conditional E-value: 9.5e-05
-TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HH CS
Met_10 99 eegevVvdvfAGiGpfaipiakyskakrvlaidlnPe 135
eg++Vv+ G+G a+++a+ s ak v+a d n +
tr|A2FYV2|A2FYV2_TRIVA 66 VEGKTVVEFGSGVGLCAVSAAV-SGAKNVVATDYNER 101
4899*****************9.99999*****9965 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (199 nodes)
Target sequences: 50190 (17055200 residues searched)
Passed MSV filter: 3880 (0.0773062); expected 1003.8 (0.02)
Passed bias filter: 1907 (0.0379956); expected 1003.8 (0.02)
Passed Vit filter: 67 (0.00133493); expected 50.2 (0.001)
Passed Fwd filter: 11 (0.000219167); expected 0.5 (1e-05)
Initial search space (Z): 50190 [actual number of targets]
Domain search space (domZ): 11 [number of targets reported over threshold]
# CPU time: 0.35u 0.01s 00:00:00.36 Elapsed: 00:00:00.14
# Mc/sec: 24242.75
//
[ok]