# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/Met_10.hmm.txt # target sequence database: proteomes/Trichoplax_adhaerens.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: Met_10 [M=199] Accession: PF02475.15 Description: Met-10+ like-protein Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.9e-67 225.2 0.0 5.9e-67 224.7 0.0 1.2 1 tr|B3SAB6|B3SAB6_TRIAD Uncharacterized protein (Fragment) OS 2.1e-30 105.3 0.0 2.9e-30 104.9 0.0 1.2 1 tr|B3RLP9|B3RLP9_TRIAD Uncharacterized protein (Fragment) OS 1.1e-08 34.4 0.0 2.1e-08 33.5 0.0 1.4 1 tr|B3RPX0|B3RPX0_TRIAD tRNA (guanine(26)-N(2))-dimethyltrans 2.6e-07 30.0 0.0 4.4e-07 29.2 0.0 1.4 1 tr|B3S2Q2|B3S2Q2_TRIAD Uncharacterized protein OS=Trichoplax 6.9e-06 25.3 0.0 1e-05 24.8 0.0 1.2 1 tr|B3RQF2|B3RQF2_TRIAD Uncharacterized protein OS=Trichoplax 1.8e-05 23.9 0.1 3.2e-05 23.1 0.1 1.3 1 tr|B3RZP1|B3RZP1_TRIAD Uncharacterized protein OS=Trichoplax 0.0012 18.0 0.1 0.0097 15.0 0.0 2.0 2 tr|B3S2L1|B3S2L1_TRIAD Uncharacterized protein (Fragment) OS 0.0049 16.0 0.1 0.013 14.6 0.0 1.6 2 tr|B3S4V8|B3S4V8_TRIAD rRNA adenine N(6)-methyltransferase O 0.007 15.5 0.1 0.011 14.9 0.1 1.2 1 tr|B3S8A4|B3S8A4_TRIAD Uncharacterized protein OS=Trichoplax 0.0075 15.4 0.0 0.012 14.7 0.0 1.2 1 tr|B3S6M9|B3S6M9_TRIAD Protein arginine N-methyltransferase ------ inclusion threshold ------ 0.025 13.7 0.1 0.092 11.9 0.0 2.0 2 tr|B3RVA6|B3RVA6_TRIAD Protein arginine N-methyltransferase Domain annotation for each sequence (and alignments): >> tr|B3SAB6|B3SAB6_TRIAD Uncharacterized protein (Fragment) OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_2329 PE=3 S # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 224.7 0.0 5.6e-70 5.9e-67 1 194 [. 120 329 .. 120 350 .. 0.94 Alignments for each domain: == domain 1 score: 224.7 bits; conditional E-value: 5.6e-70 SEEEEETTEEEEEB-TTSSHHHHHHHHHHHHHS.S-SCEEEE-S-SBTTTTB--EEEEEES-.SEEEEEETTEEEEEETTTS---GG CS Met_10 1 tkfeiiGdvvilnlreelkeykkvigevildkt.kvktvlrkvsevegefRtfelevlaGsdstetihkEngcrfklDvskvyfssk 86 t+fe +G++++lnlr +++ykk+ig+vildk+ ++ktv++k+se++ +fR+++le+laG+d ++t +kEn c+f++D+skvy++s+ tr|B3SAB6|B3SAB6_TRIAD 120 TSFESVGQIAHLNLRPPMQNYKKLIGQVILDKNpHLKTVVNKTSEIDNQFRVAPLEILAGDDCMITTVKENECQFRFDYSKVYWNSR 206 58************************************************************************************* PP GHHHHHHHHTT--TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---TT-EE... CS Met_10 87 leaErerlaklveegevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevireqlad... 170 l++E++r++ l ++ +v+vdvfAG+Gpfaip+a+ k+ +v+a+dlnP+s+++l +n k Nk+ k +++ Dgr++i++ + d tr|B3SAB6|B3SAB6_TRIAD 207 LHTEHRRIIDLLQPKQVIVDVFAGVGPFAIPAAR--KNCIVYANDLNPDSYHWLLHNSKTNKLGKQFYTFNLDGRDFIQQIVRDkii 291 **********************************..******************************************999999999 PP ..............EEEE--TTTGGGGHHHHHHHEEEE CS Met_10 171 ..............rvvmnlpksaieFldkvlaalkdg 194 +++mnlp+saieFld k+ tr|B3SAB6|B3SAB6_TRIAD 292 negttesknllvinHIIMNLPASAIEFLDVFRGLYKNS 329 ****************************9866666555 PP >> tr|B3RLP9|B3RLP9_TRIAD Uncharacterized protein (Fragment) OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_18638 PE=4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 104.9 0.0 2.7e-33 2.9e-30 35 177 .. 137 278 .. 100 303 .. 0.89 Alignments for each domain: == domain 1 score: 104.9 bits; conditional E-value: 2.7e-33 -SCEEEE-S-SBTTTTB--EEEEEES-.SEEEEEETTEEEEEETTTS---GGGHHHHHHHHTT--TT-EEEETT-TTTCCHHHCCHH CS Met_10 35 vktvlrkvsevegefRtfelevlaGsdstetihkEngcrfklDvskvyfsskleaErerlaklveegevVvdvfAGiGpfaipiaky 121 k + ++ ++ + Rt+++e+l G+ + + h +ng+++ +D++k +fs+++++E+ r+ + e++vd++AGiG+f +p + tr|B3RLP9|B3RLP9_TRIAD 137 AKRLAKNSAILNDNHRTPNVEMLLGDC-SWVTHMDNGIKYTFDITKCMFSPGNITEKIRISNFDCSEEIIVDLYAGIGYFVLPYLIH 222 55555666666999***********99.9999******************************************************* PP TTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---TT-EEEEEE--T CS Met_10 122 skakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevireqladrvvmnlp 177 +kak+v a + nP++v+ l++ + lNkv ++ +++ +D+r+ +++ +adrv ++l tr|B3RLP9|B3RLP9_TRIAD 223 AKAKFVHACEWNPHAVEALEKSLILNKVREKCTVYFGDNRQHAPKFIADRVNLGLL 278 **************************************************988876 PP >> tr|B3RPX0|B3RPX0_TRIAD tRNA (guanine(26)-N(2))-dimethyltransferase OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_53 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.5 0.0 2e-11 2.1e-08 93 198 .. 55 167 .. 47 168 .. 0.74 Alignments for each domain: == domain 1 score: 33.5 bits; conditional E-value: 2e-11 HHHTT--TT-EEEETT-TTTCCHHHCC.HHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---...TT-EE...EE CS Met_10 93 rlaklveegevVvdvfAGiGpfaipia.kyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevir...eqlad...rv 172 l + ve+g ++ + + G +i a + k k v+a+d nP+s+k +++ni+ Nk+ +vv+p +D+r ++ + +d +v tr|B3RPX0|B3RPX0_TRIAD 55 NLSAAVEKGFTIFEGLSATGLRSIRYAlELPKIKAVIANDNNPSSFKCIERNIEYNKIGHVVQPHFGDARMMMYdnsN-SLDdqfQV 140 55566666666666666667777765524568899***********************************99976642.33344433 PP E.E--TTTGGGGHHHHHHHEEEEEEEE CS Met_10 173 v.mnlpksaieFldkvlaalkdggvih 198 v ++ s Fld++++ + dgg+ + tr|B3RPX0|B3RPX0_TRIAD 141 VdIDPYGSPAIFLDAAVQSVSDGGLLC 167 314455677789999999999999887 PP >> tr|B3S2Q2|B3S2Q2_TRIAD Uncharacterized protein OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_58107 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.2 0.0 4.2e-10 4.4e-07 102 184 .. 563 643 .. 546 714 .. 0.89 Alignments for each domain: == domain 1 score: 29.2 bits; conditional E-value: 4.2e-10 -EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---TT-EEEEEE--TTTGGGGH CS Met_10 102 evVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevireqladrvvmnlpksaieFl 184 +++d f G+G i ak v+aid++P+ +k ++n k +ve++++ i +D +++++ +ad v + p +l tr|B3S2Q2|B3S2Q2_TRIAD 563 SIIIDAFCGVGGNCIQFAK--TCDHVIAIDIDPNKIKCARHNAKIYNVEHKIEFIVGDFLQLAPSLKADVVFLSPPWGGPTYL 643 5799***************..77789*************************************99999987776665555555 PP >> tr|B3RQF2|B3RQF2_TRIAD Uncharacterized protein OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_54966 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.8 0.0 9.5e-09 1e-05 100 180 .. 49 129 .. 41 151 .. 0.86 Alignments for each domain: == domain 1 score: 24.8 bits; conditional E-value: 9.5e-09 TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTC..EEEEES-GGG---TT-EEEEEE--TTTG CS Met_10 100 egevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekv..vkpileDgrevireqladrvvmnlpksa 180 +g++V+d+ G G +++ a +a+ +++id++ ++ ++ni+ ++e+v +k+ +D++ + +++d v+mn p + tr|B3RQF2|B3RQF2_TRIAD 49 QGKLVCDLGCGCGVLSVGTAM-LDASLIVGIDIDDDALMIARRNIEEFELENVqlIKANISDTEFFG-GKIFDTVIMNPPFGT 129 699*****************7.89999*******************999997544999999998885.99********88655 PP >> tr|B3RZP1|B3RZP1_TRIAD Uncharacterized protein OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_26585 PE=3 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.1 0.1 3.1e-08 3.2e-05 95 184 .. 156 246 .. 151 264 .. 0.82 Alignments for each domain: == domain 1 score: 23.1 bits; conditional E-value: 3.1e-08 HTT--TT-EEEETT-TTTCCH.HHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---.TT-EEEEEE--TTT CS Met_10 95 aklveegevVvdvfAGiGpfa.ipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevir.eqladrvvmnlpks 179 a ++++e V+d+ G + +a + + +++a+d+n e k l+ ni++ v +++ + e gr++ + +drv++++p s tr|B3RZP1|B3RZP1_TRIAD 156 ALAAQPNEKVLDMCSAPGGKTtYIAALMKNTGMIVANDVNKERCKALTANIHRLGVVNTI-VCSENGRQFPKiVGGFDRVLLDAPCS 241 55689********97665544044455567889*********************999999.88999****999999******99987 PP GGGGH CS Met_10 180 aieFl 184 + + tr|B3RZP1|B3RZP1_TRIAD 242 GTGVI 246 66655 PP >> tr|B3S2L1|B3S2L1_TRIAD Uncharacterized protein (Fragment) OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_1535 PE=3 S # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.0 0.0 9.3e-06 0.0097 100 183 .. 50 134 .. 34 151 .. 0.78 2 ? 0.4 0.0 0.28 3e+02 5 40 .. 295 332 .. 292 343 .. 0.67 Alignments for each domain: == domain 1 score: 15.0 bits; conditional E-value: 9.3e-06 TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---TT-EEEEE...E--TTTGGGG CS Met_10 100 egevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevireqladrvv...mnlpksaieF 183 +++vV+dv AG G ++ + + + a++v+a++ +++ ++ i+ N+++ +++ +++ +e+ ++ +d ++ m+++ + tr|B3S2L1|B3S2L1_TRIAD 50 QNKVVLDVGAGSGILSFFAVQ-AGARKVYAVEASSIAIH-AENLIHSNQLSPKIQIVKGRIEEIEIPEPIDMIIsepMGYMLFNERM 134 699**********99987776.88999*****9877776.46669*********999999999988888887775555555555555 PP == domain 2 score: 0.4 bits; conditional E-value: 0.28 EETTEE..EEEB-.TTSSHHHHHHHHHHHHHSS-SCEEE CS Met_10 5 iiGdvv..ilnlr.eelkeykkvigevildktkvktvlr 40 ++Gdv+ ++ + + + y+ +i v l+ t vktv + tr|B3S2L1|B3S2L1_TRIAD 295 RAGDVItgHISMVaNTRQSYDVEIMTV-LQSTGVKTVAE 332 566666333333303445699999987.99999**9976 PP >> tr|B3S4V8|B3S4V8_TRIAD rRNA adenine N(6)-methyltransferase OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_29342 PE=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.6 0.0 1.2e-05 0.013 98 178 .. 21 98 .. 13 111 .. 0.86 2 ? -1.8 0.1 1.4 1.4e+03 21 47 .. 229 255 .. 207 264 .. 0.54 Alignments for each domain: == domain 1 score: 14.6 bits; conditional E-value: 1.2e-05 --TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---TT-EEEEEE--TT CS Met_10 98 veegevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevireqladrvvmnlpk 178 ++ ++V+++ G G +++ + + kak+v+a +++P+ l++ ++ v+ +++ i +D+ + +d v nlp+ tr|B3S4V8|B3S4V8_TRIAD 21 IRSTDTVLEIGPGTGNLTVKLLQ--KAKKVIACEVDPRLAAELQKRVQGSPVSTKLHIIVGDVLKTE-LPYFDVCVANLPY 98 56778999999********9998..*************************************98875.5567777777775 PP == domain 2 score: -1.8 bits; conditional E-value: 1.4 HHHHHHHHHHHHSS-SCEEEE-S-SBT CS Met_10 21 ykkvigevildktkvktvlrkvseveg 47 +++ i e i +kv t+l+ v+ + tr|B3S4V8|B3S4V8_TRIAD 229 HNQAIEEDINIAEKVDTILKSVNANAR 255 555566665555566666666655333 PP >> tr|B3S8A4|B3S8A4_TRIAD Uncharacterized protein OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_60467 PE=3 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.9 0.1 1e-05 0.011 100 179 .. 27 104 .. 2 127 .. 0.77 Alignments for each domain: == domain 1 score: 14.9 bits; conditional E-value: 1e-05 TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---TT-EEEEEE--TTT CS Met_10 100 egevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevireqladrvvmnlpks 179 ++vV+dv AG G ++ + + a++v+a++ + + k ++ N+ ++++++i+ ++++ ++++d +v + + + tr|B3S8A4|B3S8A4_TRIAD 27 RNKVVLDVGAGTGILSHFCVE-AGARKVYAVEASAIAEQAKKVAL-ANNAQDKISVINDLVENIELPEKVDVIVSEWMGY 104 589**********99988876.78999*****9988877655554.5788999999999999998899999888665554 PP >> tr|B3S6M9|B3S6M9_TRIAD Protein arginine N-methyltransferase OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_59862 PE= # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.7 0.0 1.2e-05 0.012 103 177 .. 340 417 .. 336 443 .. 0.77 Alignments for each domain: == domain 1 score: 14.7 bits; conditional E-value: 1.2e-05 EEEETT-TTTCCHHHCCH..HT..TSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---TT-EEEEEE--T CS Met_10 103 vVvdvfAGiGpfaipiak..ys..kakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevireqladrvvmnlp 177 vV+ + AG Gp+ + + ys + +v+ai++nP++v l +n+k + + v+++ +D re ++++ad +v +l tr|B3S6M9|B3S6M9_TRIAD 340 VVMVLGAGRGPLVKATLRagYSlqTKLTVYAIEKNPNAVITL-QNLKAVEWGDQVTVVSTDMREWEPPCKADIIVSELL 417 5666667777764333221133214567***********888.599999999********************9987765 PP >> tr|B3RVA6|B3RVA6_TRIAD Protein arginine N-methyltransferase OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_55586 PE= # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 0.0 8.8e-05 0.092 103 177 .. 70 148 .. 30 167 .. 0.85 2 ? -2.7 0.0 2.5 2.6e+03 137 156 .. 189 208 .. 181 219 .. 0.78 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 8.8e-05 EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---.....TT-EEEEEE--T CS Met_10 103 vVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevir.....eqladrvvmnlp 177 V+d+ G G +a+ +a+ + ak+++a + ++ ++ i+ N+ ++ +k i++ + ++ ++ad +vm++ tr|B3RVA6|B3RVA6_TRIAD 70 NVLDIGTGTGLLALMAAR-AGAKKIYACEAFQPMAQLAQKIITENRYQDNIKIIQKRSTSMTAdddmdGCKADLIVMEIF 148 699**************9.88899****987667799*****************99999998844333445668888765 PP == domain 2 score: -2.7 bits; conditional E-value: 2.5 HHHHHHHHHHTT-TTCEEEE CS Met_10 137 vkylkeniklNkvekvvkpi 156 k+l++ +lN v++ +++ tr|B3RVA6|B3RVA6_TRIAD 189 SKFLQKCCNLNPVKSQMSVR 208 589999*****999887654 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (199 nodes) Target sequences: 11518 (5222075 residues searched) Passed MSV filter: 435 (0.037767); expected 230.4 (0.02) Passed bias filter: 293 (0.0254384); expected 230.4 (0.02) Passed Vit filter: 41 (0.00355965); expected 11.5 (0.001) Passed Fwd filter: 11 (0.000955027); expected 0.1 (1e-05) Initial search space (Z): 11518 [actual number of targets] Domain search space (domZ): 11 [number of targets reported over threshold] # CPU time: 0.09u 0.01s 00:00:00.10 Elapsed: 00:00:00.04 # Mc/sec: 25979.82 // [ok]