# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/Met_10.hmm.txt
# target sequence database: proteomes/Trypanosoma_brucei.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: Met_10 [M=199]
Accession: PF02475.15
Description: Met-10+ like-protein
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
1.9e-46 157.3 0.1 1.6e-33 115.1 0.0 2.2 2 tr|Q57X10|Q57X10_TRYB2 tRNA (guanine(37)-N1)-methyltransfera
1.2e-39 135.1 0.0 1.5e-35 121.7 0.1 2.4 2 tr|Q38BT8|Q38BT8_TRYB2 Uncharacterized protein OS=Trypanosom
3.8e-06 25.7 0.0 5.3e-06 25.3 0.0 1.3 1 sp|Q582G4|ANM7_TRYB2 Protein arginine N-methyltransferase
0.00043 19.1 0.0 0.00074 18.3 0.0 1.3 1 tr|Q389Z0|Q389Z0_TRYB2 Uncharacterized protein OS=Trypanosom
0.0017 17.1 0.1 0.0026 16.5 0.1 1.2 1 tr|Q4GYA9|Q4GYA9_TRYB2 Arginine N-methyltransferase, putativ
------ inclusion threshold ------
0.035 12.8 0.0 0.05 12.3 0.0 1.2 1 tr|Q57U70|Q57U70_TRYB2 Arginine N-methyltransferase, putativ
0.045 12.5 0.0 0.076 11.7 0.0 1.3 1 tr|Q57ZS4|Q57ZS4_TRYB2 Uncharacterized protein OS=Trypanosom
0.065 11.9 0.0 0.095 11.4 0.0 1.2 1 tr|Q381M3|Q381M3_TRYB2 Uncharacterized protein OS=Trypanosom
Domain annotation for each sequence (and alignments):
>> tr|Q57X10|Q57X10_TRYB2 tRNA (guanine(37)-N1)-methyltransferase OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 39.9 0.0 1.6e-13 1.8e-10 2 58 .. 169 226 .. 168 239 .. 0.95
2 ! 115.1 0.0 1.5e-36 1.6e-33 65 186 .. 277 409 .. 268 422 .. 0.92
Alignments for each domain:
== domain 1 score: 39.9 bits; conditional E-value: 1.6e-13
EEEEETTEEEEEB-TTSSHHHHHHHHHHHHHS.S-SCEEEE-S-SBTTTTB--EEEEE CS
Met_10 2 kfeiiGdvvilnlreelkeykkvigevildkt.kvktvlrkvsevegefRtfelevla 58
+fe+iG+++++nl++e +yk ig vil + v v++kv++++++fR+f++e++a
tr|Q57X10|Q57X10_TRYB2 169 GFEQIGHIAHVNLSAEHLPYKMAIGAVILSCNpTVSVVVNKVNSISSVFREFKMEIVA 226
79******************************99**********************98 PP
== domain 2 score: 115.1 bits; conditional E-value: 1.5e-36
EEEEETTEEEEEETTTS---GGGHHHHHHHHTT--TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TT CS
Met_10 65 tihkEngcrfklDvskvyfsskleaErerlaklveegevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvek 151
++ +gc+f++ + +vy++s+l++E++r+++l++ g+v dv+AG+Gpfa+p+a +++v+a+dlnP + +yl+ n N++ k
tr|Q57X10|Q57X10_TRYB2 277 ATVRQHGCTFRVPYDRVYWNSRLSHEHTRIVELMQRGDVLYDVMAGVGPFAVPAAS--AGVTVYANDLNPVAAEYLRINADINHIRK 361
56899**************************************************7..99*************************75 PP
.CEEEEES-GGG---TT-EE............EEEE--TTTGGGGHHH CS
Met_10 152 .vvkpileDgrevireqlad............rvvmnlpksaieFldk 186
+ ++ Dgre++++ l + +v mnlp+ a+eFld
tr|Q57X10|Q57X10_TRYB2 362 dSFHIFNIDGREFMNTILYNdvianssrcgrrHVTMNLPAIAVEFLDV 409
278899********97666679999*********************96 PP
>> tr|Q38BT8|Q38BT8_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 11.4 0.0 9.1e-05 0.097 2 64 .. 87 153 .. 86 179 .. 0.79
2 ! 121.7 0.1 1.4e-38 1.5e-35 50 199 .] 175 334 .. 157 334 .. 0.90
Alignments for each domain:
== domain 1 score: 11.4 bits; conditional E-value: 9.1e-05
EEEEETTEEEEEB.....-TTSSHHHHHHHHHHHHHSS-SCEEEE-S-SBTTTTB--EEEEEES-.SE CS
Met_10 2 kfeiiGdvvilnl.....reelkeykkvigevildktkvktvlrkvsevegefRtfelevlaGsdste 64
+fe +G+vv+++l r+ + +y++ ++e + + + vl ++ + ge+R+++levl s++++
tr|Q38BT8|Q38BT8_TRYB2 87 HFELVGHVVVVKLnrgiaRDVFAPYARALAESFFPR-VIDVVLLDTMGIVGELREPHLEVLWSSATSH 153
699********9922222345678888888886654.6899********************9887544 PP
== domain 2 score: 121.7 bits; conditional E-value: 1.4e-38
TB--EEEEEE..S-.SEEEEEETTEEEEEETTTS---GGGHHHHHHHHTT--TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-H CS
Met_10 50 RtfelevlaG..sdstetihkEngcrfklDvskvyfsskleaErerlaklveegevVvdvfAGiGpfaipiakyskakrvlaidlnP 134
+ e+l ++ t t h Eng+r+ +D kv+f s++ +Er+ a+++ ++evVvd+fAGiG+f++p+a + k+v a ++n
tr|Q38BT8|Q38BT8_TRYB2 175 TSEDAELLGScaEAVTFTTHVENGVRYSFDACKVMFCSGNVTERMHFASIIAKDEVVVDMFAGIGYFTLPLAINGGVKIVHALEKNK 261
445555554344667889********************************************************************* PP
HHHHHHHHHHHHTT-TTCEEEEES-GGG---..TT-EEEEEE--TTTGGGGHHHHHHHEEEE......EEEEE CS
Met_10 135 esvkylkeniklNkvekvvkpileDgrevir..eqladrvvmnlpksaieFldkvlaalkdg......gvihy 199
+s yl n Nkv++ + ++D+r+v drv+m+++ s+++Fl ++++l++ gv+hy
tr|Q38BT8|Q38BT8_TRYB2 262 YSALYLAFNAVQNKVSDLIVIHCGDNRDVGSelCGRCDRVIMGYIPSCESFLPRAISFLRRStrgepmGVVHY 334
*****************************98666789**********************99989999999999 PP
>> sp|Q582G4|ANM7_TRYB2 Protein arginine N-methyltransferase 7 OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 25.3 0.0 4.9e-09 5.3e-06 92 168 .. 87 162 .. 67 255 .. 0.83
Alignments for each domain:
== domain 1 score: 25.3 bits; conditional E-value: 4.9e-09
HHHHTT--TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---TT- CS
Met_10 92 erlaklveegevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevireql 168
e l k v + V+++ AG G +++ +ak++ ak v+a++ e k+ +eni+ N++e+ vk++ + + e+ ++l
sp|Q582G4|ANM7_TRYB2 87 EVLKKHVTPETGVLEIGAGSGLLSLMAAKLG-AKWVVAVEGSEELAKLARENIRANNMEHQVKVLHMMSTELKSKHL 162
4567779999*******************66.677******************************999888876655 PP
>> tr|Q389Z0|Q389Z0_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 18.3 0.0 6.9e-07 0.00074 103 151 .. 213 261 .. 199 275 .. 0.91
Alignments for each domain:
== domain 1 score: 18.3 bits; conditional E-value: 6.9e-07
EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TT CS
Met_10 103 vVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvek 151
+V+d+ G G i+iak+ +v a+d+ e++ +en klN +e
tr|Q389Z0|Q389Z0_TRYB2 213 RVLDMCCGTGCVGIAIAKHVPSAQVTAVDILDEAIGASEENAKLNGLEA 261
69*******************************************9875 PP
>> tr|Q4GYA9|Q4GYA9_TRYB2 Arginine N-methyltransferase, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 16.5 0.1 2.4e-06 0.0026 100 176 .. 53 130 .. 40 164 .. 0.84
Alignments for each domain:
== domain 1 score: 16.5 bits; conditional E-value: 2.4e-06
TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---TT-EEEEE...E-- CS
Met_10 100 egevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevireqladrvv...mnl 176
+++vV+dv G G +++ +ak + a++v+++d +v+ +e ++ N e+v++ i++ ++e+ ++++d ++ m++
tr|Q4GYA9|Q4GYA9_TRYB2 53 KDKVVLDVGCGTGILSMFAAK-AGARKVIGVDCSTVAVQ-AREIVRDNGFEDVITIIQGKVEEIQLDEKVDIIIsewMGY 130
468*****************9.88999*******99998.5899********************9999999777333444 PP
>> tr|Q57U70|Q57U70_TRYB2 Arginine N-methyltransferase, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 12.3 0.0 4.7e-05 0.05 98 167 .. 52 119 .. 26 179 .. 0.75
Alignments for each domain:
== domain 1 score: 12.3 bits; conditional E-value: 4.7e-05
--TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---TT CS
Met_10 98 veegevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevireq 167
eg+vVvdv G G +++ +a+ + ak v++i+ s ++ ++ N+++ +++++ ++++i
tr|Q57U70|Q57U70_TRYB2 52 SIEGKVVVDVGSGTGILSMWAAR-AGAKHVFSIEASSLS-EFQIGVVEDNDLSTKITVLGDTVENIIAGG 119
569*******************9.88999****987655.666677888888888855444455555544 PP
>> tr|Q57ZS4|Q57ZS4_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 11.7 0.0 7.1e-05 0.076 91 148 .. 83 137 .. 66 148 .. 0.78
Alignments for each domain:
== domain 1 score: 11.7 bits; conditional E-value: 7.1e-05
HHHHHTT--TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT CS
Met_10 91 rerlaklveegevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNk 148
++ + + ++ Vv++ AG+G + i +a + rv+ d+ e v ++++ni+lNk
tr|Q57ZS4|Q57ZS4_TRYB2 83 QKHVLQNHDKACHVVELGAGVGCLGIGLAM--AGARVVITDMK-ELVPLMEKNIELNK 137
455666667777899**************8..66668888987.8899*********9 PP
>> tr|Q381M3|Q381M3_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 11.4 0.0 8.8e-05 0.095 98 153 .. 116 172 .. 110 207 .. 0.82
Alignments for each domain:
== domain 1 score: 11.4 bits; conditional E-value: 8.8e-05
--TT-EEEETT-TTTCCHHHCCHH.TTSSEEEEEES-HHHHHHHHHHHHHTT-TTCE CS
Met_10 98 veegevVvdvfAGiGpfaipiaky.skakrvlaidlnPesvkylkeniklNkvekvv 153
v++ ++V+d+ AG+G +i+i+++ s+ + a++ + l++nik +++v
tr|Q381M3|Q381M3_TRYB2 116 VQQFDLVLDLCAGVGGKSIAISQFlSNSASLTANEQRGDRCARLRRNIKEYVPSNYV 172
677899***************9964888999*****999999999999977666666 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (199 nodes)
Target sequences: 8561 (4332363 residues searched)
Passed MSV filter: 265 (0.0309543); expected 171.2 (0.02)
Passed bias filter: 220 (0.0256979); expected 171.2 (0.02)
Passed Vit filter: 23 (0.0026866); expected 8.6 (0.001)
Passed Fwd filter: 8 (0.00093447); expected 0.1 (1e-05)
Initial search space (Z): 8561 [actual number of targets]
Domain search space (domZ): 8 [number of targets reported over threshold]
# CPU time: 0.08u 0.00s 00:00:00.08 Elapsed: 00:00:00.04
# Mc/sec: 21553.51
//
[ok]