# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/Methyltr_RsmB-F.hmm.txt
# target sequence database: proteomes/Danio_rerio.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: Methyltr_RsmB-F [M=200]
Accession: PF01189.16
Description: 16S rRNA methyltransferase RsmB/F
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
2.5e-77 259.6 0.0 5.1e-77 258.6 0.0 1.5 1 tr|F1QWP7|F1QWP7_DANRE NOP2 nucleolar protein homolog (
6.3e-44 150.5 0.0 9.6e-44 149.9 0.0 1.3 1 tr|A0A0R4IAT4|A0A0R4IAT4_DANRE NOL1/NOP2/Sun domain family, mem
6.8e-37 127.6 0.0 1.4e-35 123.3 0.0 2.3 1 tr|A5PMI3|A5PMI3_DANRE NOP2/Sun RNA methyltransferase f
1.4e-32 113.5 0.0 2.6e-32 112.6 0.0 1.4 1 tr|F1RDI6|F1RDI6_DANRE NOP2/Sun domain family, member 5
4.3e-30 105.4 0.0 6.1e-30 104.9 0.0 1.3 1 sp|Q4KMK0|NSUN3_DANRE tRNA (cytosine(34)-C(5))-methylt
3e-29 102.6 0.1 4.3e-29 102.1 0.1 1.2 1 tr|B8JM23|B8JM23_DANRE NOL1/NOP2/Sun domain family, mem
------ inclusion threshold ------
0.14 12.3 0.0 0.32 11.1 0.0 1.6 1 tr|A0A1D5NT05|A0A1D5NT05_DANRE Methyltransferase-like 15 OS=Dan
Domain annotation for each sequence (and alignments):
>> tr|F1QWP7|F1QWP7_DANRE NOP2 nucleolar protein homolog (yeast) OS=Danio rerio OX=7955 GN=nop2 PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 258.6 0.0 1.4e-80 5.1e-77 1 200 [] 375 583 .. 375 583 .. 0.94
Alignments for each domain:
== domain 1 score: 258.6 bits; conditional E-value: 1.4e-80
HHHH---TT-EEEECS-TT-HHHHHHHHHTTTTSEEEEEESSCCCHHHHHHHHHHTT--SEEEEES-CCCCHHHHCC--EEEEEEEE CS
Methyltr_RsmB-F 1 allLapqeeetilDlcaaPGgKTthiaelmknkgtvvAvdankeRlkrvaenlkrLgvtntivleaDarkidkvlggelfDriLlDa 87
+++L pqe+e +lD++aaPGgKTt++a+lm+n+g +vA+dan Rlk+v+ n++rLgvtn+ ++++D+r+++kv+gg fDr+LlDa
tr|F1QWP7|F1QWP7_DANRE 375 VMALSPQEGESVLDMSAAPGGKTTYMAQLMRNTGMIVANDANVDRLKSVVGNIHRLGVTNAVICNYDGRQFPKVMGG--FDRVLLDA 459
589*************************************************************************9..******** PP
--CCGGGTTT-TTHHHH.-CCHHCCHHHHHHHHHHHHHHHE....EEEEEEEEEES---CTCTHHHHHHHHHH-TTEEEESSBSTTS CS
Methyltr_RsmB-F 88 PCsgtgvirrdpdvklrrkekdiaqlaklqkellsaaidll....kkgGvlvYsTCsvlveEneevieeaLkkredvelvetelsep 170
PCsgtgvi++dp+vk+ ++e+di + a+lqkel+ +aid++ ++gG+lvY+TCs+ veEne+v+++aLkkr +v+lv+t l +
tr|F1QWP7|F1QWP7_DANRE 460 PCSGTGVISKDPAVKTGKDEADILRSAHLQKELILSAIDSVnadsQTGGYLVYCTCSIMVEENEWVVDYALKKR-NVKLVPTGLDFG 545
*****************************************99999***************************9.9******66433 PP
TTSSECEEC..............T-EEE-TTTTS.-SEEEEEEE CS
Methyltr_RsmB-F 171 kglklgeea..............gtlrllPhtenkdgffiaklk 200
+e +r++Ph++n+dgff+aklk
tr|F1QWP7|F1QWP7_DANRE 546 ------KEGftrfkekrfhpslkLSRRFYPHSHNMDGFFVAKLK 583
......3333333345799*99999*****************96 PP
>> tr|A0A0R4IAT4|A0A0R4IAT4_DANRE NOL1/NOP2/Sun domain family, member 6 OS=Danio rerio OX=7955 GN=nsun6 PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 149.9 0.0 2.6e-47 9.6e-44 2 199 .. 226 456 .. 225 457 .. 0.85
Alignments for each domain:
== domain 1 score: 149.9 bits; conditional E-value: 2.6e-47
HHH---TT-EEEECS-TT-HHHHHHHHHTTTTSEEEEEESSCCCHHHHHHHHHHTT--SEEEEES-.CCCCHHHHCC.. CS
Methyltr_RsmB-F 2 llLapqeeetilDlcaaPGgKTthiaelmknkgtvvAvdankeRlkrvaenlkrLgvtntivleaD.arkidkvlgg.. 77
++L p+++e++lD+caaPGgKTthia lm n+g+vvA+++ +++++++ +n + L + ++ + + ++++ ++
tr|A0A0R4IAT4|A0A0R4IAT4_DANRE 226 YVLGPRPGERVLDMCAAPGGKTTHIASLMGNQGVVVALEKVRSKMEKILRNAQMLKLDCIKAYCCNsIHAVSSDPAQey 304
5899*************************************************99988444333220222233333256 PP
........--EEEEEEEE--CCGGGTTT-TTHHHH.-CCHHCCHHHHHHHHHHHHHHHEEEEEEEEEEES---CTCTHH CS
Methyltr_RsmB-F 78 ........elfDriLlDaPCsgtgvirrdpdvklrrkekdiaqlaklqkellsaaidllkkgGvlvYsTCsvlveEnee 148
e fDriLlDaPCsg+g ++p++ ++ + k++ +++ lq++l+++a+ llk+gGvlvYsTC+v+++Enee
tr|A0A0R4IAT4|A0A0R4IAT4_DANRE 305 tegppfpeESFDRILLDAPCSGLG---QRPNMSYSWSLKEVCSYQPLQRKLFTTAVRLLKSGGVLVYSTCTVTLAENEE 380
66899999**************98...7899999999****************************************** PP
HHHHHHHH-TTEEEESSBSTTSTTSSECEEC.......................T-EEE-TTTTS.-..SEEEEEE CS
Methyltr_RsmB-F 149 vieeaLkkredvelvetelsepkglklgeea.......................gtlrllPhtenkd..gffiakl 199
++ aLk+ + l++ + +++ lg + l+ lP+ n+d gffiak+
tr|A0A0R4IAT4|A0A0R4IAT4_DANRE 381 QVSWALKTFPCLTLQPQVPHVGSEGMLGAGLsceqrrllqrfrpelgwtgerftFSLEKLPQDANQDtiGFFIAKF 456
**********9999987554444444444445666999999*****999999987888999999999778999998 PP
>> tr|A5PMI3|A5PMI3_DANRE NOP2/Sun RNA methyltransferase family, member 2 OS=Danio rerio OX=7955 GN=nsun2 PE=1 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 123.3 0.0 3.8e-39 1.4e-35 2 199 .. 164 421 .. 163 422 .. 0.89
Alignments for each domain:
== domain 1 score: 123.3 bits; conditional E-value: 3.8e-39
HHH---TT-EEEECS-TT-HHHHHHHHHTT.......TTSEEEEEESSCCCHHHHHHHHHHTT--SEEEEES-CCCCHHHHCC.... CS
Methyltr_RsmB-F 2 llLapqeeetilDlcaaPGgKTthiaelmk.......nkgtvvAvdankeRlkrvaenlkrLgvtntivleaDarkidkvlgg.... 77
llL+ +++ +ilD+caaPG+KT+ + e+++ ++g v+A+d++++R +++ krL+ ++v++ Da+ i++ +
tr|A5PMI3|A5PMI3_DANRE 164 LLLKIEPQHKILDMCAAPGSKTAQLIEMLHsdmdvpfPEGFVIANDVDNKRCYLLVHQAKRLNSPCIMVVNHDASSIPRLHFDnngk 250
57999999*******************976222233347899**********************************99987766778 PP
...--EEEEEEEE--CCGGGTTT-TTHHHH.-CCHHCCHHHHHHHHHHHHHHHEEEEEEEEEEES---CTCTHHHHHHHHHH-T.TE CS
Methyltr_RsmB-F 78 ...elfDriLlDaPCsgtgvirrdpdvklrrkekdiaqlaklqkellsaaidllkkgGvlvYsTCsvlveEneevieeaLkkre.dv 160
++DriL D+PCsg g++r++ dv + + ++ +l+ lq ++ +++l gG +vYsTCs+++ E+e+vi+++L+k e
tr|A5PMI3|A5PMI3_DANRE 251 kdiLFYDRILCDVPCSGDGTMRKNIDVWKKWTTSNSLHLHGLQLRIAVRGVEQLAVGGRMVYSTCSLNPIEDEAVIAALLEKSEgSL 337
897789*********************7777889999*******************************************9987245 PP
EEESSBSTTSTTSSECEEC..............................................T-EEE-TTTTS.-SEEEEEE CS
Methyltr_RsmB-F 161 elvetelsepkglklgeea..............................................gtlrllPhtenkdgffiakl 199
el + + glk+ + +r+lPh++n+ gff+a l
tr|A5PMI3|A5PMI3_DANRE 338 ELADA-SPDLPGLKYMPGItswkvmtkegqwfsnfsevptsrhtqirptmfppsdsekltemrleRCVRILPHHQNTGGFFVAVL 421
66555.55656666555556699999*************************************9999***************987 PP
>> tr|F1RDI6|F1RDI6_DANRE NOP2/Sun domain family, member 5 OS=Danio rerio OX=7955 GN=nsun5 PE=1 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 112.6 0.0 7.1e-36 2.6e-32 2 199 .. 218 414 .. 217 415 .. 0.91
Alignments for each domain:
== domain 1 score: 112.6 bits; conditional E-value: 7.1e-36
HHH---TT-EEEECS-TT-HHHHHHHHHTTTTSEEEEEESSCCCHHHHHHHHHHTT--SEEEEES-CCCCHHHHCC.--EEEEEEEE CS
Methyltr_RsmB-F 2 llLapqeeetilDlcaaPGgKTthiaelmknkgtvvAvdankeRlkrvaenlkrLgvtntivleaDarkidkvlgg.elfDriLlDa 87
lL+p + +++D+caaPG KT+h+a++mknkg+++A d +++Rl+ + + l r gvt ++ + D k+d ++ + + iLlD
tr|F1RDI6|F1RDI6_DANRE 218 FLLNPPVGSHVIDACAAPGNKTSHLAAIMKNKGKLFAFDLDAKRLSTMSTLLLRAGVTCHKLANQDFLKVDPQNSEyKEVKYILLDP 304
689*******************************************************************999998899******** PP
--CCGGGTTT-TTHHHH.-CCHHCCHHHHHHHHHHHHHHHEEEEEEEEEEES---CTCTHHHHHHHHHH-TTEEEESSBSTTSTTSS CS
Methyltr_RsmB-F 88 PCsgtgvirrdpdvklrrkekdiaqlaklqkellsaaidllkkgGvlvYsTCsvlveEneevieeaLkkredvelvetelsepkglk 174
Csg g++ + ++ ++++ +++la q + l+ a++ + + +vYsTCs++ +Eneev+ + L++++ +lv++ l + +
tr|F1RDI6|F1RDI6_DANRE 305 SCSGSGMVCLRDELPETQEDGRLQALAAFQLHCLNHALQFPQLE-RIVYSTCSIHSQENEEVVTACLQRNPGFRLVHL-LPDWPERG 389
*************************************9987665.79*****************************99.44433333 PP
ECEECT-EEE-TTTTS.-SEEEEEE CS
Methyltr_RsmB-F 175 lgeeagtlrllPhtenkdgffiakl 199
+ ++ lr + + gff+a l
tr|F1RDI6|F1RDI6_DANRE 390 HEPLTQCLRASTAKTRTHGFFVAML 414
33333468888999999*****987 PP
>> sp|Q4KMK0|NSUN3_DANRE tRNA (cytosine(34)-C(5))-methyltransferase, mitochondrial OS=Danio rerio OX=7955 GN=nsun3 PE=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 104.9 0.0 1.7e-33 6.1e-30 2 168 .. 156 325 .. 155 364 .. 0.82
Alignments for each domain:
== domain 1 score: 104.9 bits; conditional E-value: 1.7e-33
HHH---TT-EEEECS-TT-HHHHHHHHHTTTTSEEEEEESSCCCHHHHHHHHHHT...T--.SEEEEES-CCCCHHHHCC--EEEEEE CS
Methyltr_RsmB-F 2 llLapqeeetilDlcaaPGgKTthiaelmknkgtvvAvdankeRlkrvaenlkrL...gvt.ntivleaDarkidkvlggelfDriLl 85
l+L+ qe+e +lDlcaaPGgK i++ ++ g + ++++++R + + ++l+ +++ + v+ D+r i ++ g +D++L+
sp|Q4KMK0|NSUN3_DANRE 156 LALNVQEGENVLDLCAAPGGKSLAILQT-ATPGLLHCNEVDQHRHDWLLKTLESYvppSLRhLLSVTLQDGRSIGTMQPG-AYDKVLV 241
78*************************9.999******************999752222332368999******998887.9****** PP
EE--CCGGGTTT-TTHH.HH.-CCHHCCHHHHHHHHHHHHHHHEEEEEEEEEEES---CTCTHHHHHHHHHH-TTEEEESSBST CS
Methyltr_RsmB-F 86 DaPCsgtgvirrdpdvk.lrrkekdiaqlaklqkellsaaidllkkgGvlvYsTCsvlveEneevieeaLkkredvelvetels 168
DaPCs pd + + k+ +ql lqkell +a++ +++gG++vYsTC++ +En+ v+ee+L + + vel+e+e +
sp|Q4KMK0|NSUN3_DANRE 242 DAPCSNDRSWLYTPDTHrGEMWLKERTQLPLLQKELLCSALAAVRPGGIVVYSTCTMSRAENQSVVEEVLASYPGVELQELEQQ 325
******9998888887312333466779999***********************************************998544 PP
>> tr|B8JM23|B8JM23_DANRE NOL1/NOP2/Sun domain family, member 4 OS=Danio rerio OX=7955 GN=nsun4 PE=1 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 102.1 0.1 1.2e-32 4.3e-29 2 168 .. 176 348 .. 175 374 .. 0.82
Alignments for each domain:
== domain 1 score: 102.1 bits; conditional E-value: 1.2e-32
HHH---TT-EEEECS-TT-HHHHHHHHHTTTTSEEEEEESSCCCHHHHHHHHHH......TT--SEEEEES-CCCCHHHHCC--EEE CS
Methyltr_RsmB-F 2 llLapqeeetilDlcaaPGgKTthiaelmknkgtvvAvdankeRlkrvaenlkr......LgvtntivleaDarkidkvlggelfDr 82
l+L+ ++++t+lDlcaaPGgKT +++ ++ +++ A+d + +R+ r+ + l+ L +n+ +++ D+r+ + ++ fDr
tr|B8JM23|B8JM23_DANRE 176 LALDVRPGQTVLDLCAAPGGKTLALLQA-HSVNHLWANDLSVSRTGRLRKILQSyvpkefLDEENIHITCIDGRELG-MREEKSFDR 260
68999********************999.88999*********999998877653333337788************5.55557**** PP
EEEEE--CCG..GGTTT-TTHHHH.-CCHHCCHHHHHHHHHHHHHHHEEEEEEEEEEES---CTCTHHHHHHHHHH-TTEEEESSBS CS
Methyltr_RsmB-F 83 iLlDaPCsgt..gvirrdpdvklrrkekdiaqlaklqkellsaaidllkkgGvlvYsTCsvlveEneevieeaLkkredvelvetel 167
+L+D+PC++ ++ ++++ r + k+ ++l lq +ll a i+ ++gG +vYsTCs+ ne v+++a++ ++ +++++
tr|B8JM23|B8JM23_DANRE 261 VLVDVPCTTDrhSAVVEENNIFKRSRTKERQKLPLLQIQLLVAGIQAARQGGLIVYSTCSLSQLQNECVVQQAISVAQEELGITVQV 347
********852244555555655555677899*****************************************99876555555555 PP
T CS
Methyltr_RsmB-F 168 s 168
+
tr|B8JM23|B8JM23_DANRE 348 Q 348
5 PP
>> tr|A0A1D5NT05|A0A1D5NT05_DANRE Methyltransferase-like 15 OS=Danio rerio OX=7955 GN=mettl15 PE=1 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 11.1 0.0 8.7e-05 0.32 3 93 .. 78 171 .. 76 185 .. 0.75
Alignments for each domain:
== domain 1 score: 11.1 bits; conditional E-value: 8.7e-05
HH---TT-EEEECS-TT-HHHHHHHHHTTTTSEEEEEESSCCCHHHHHHHHHHTT--SEEEEES-CCCCHHHHCC.... CS
Methyltr_RsmB-F 3 lLapqeeetilDlcaaPGgKTthiaelmknkgtvvAvdankeRlkrvaenlkrLgvtntivleaDarkidkvlgg.... 77
+L+ ++++ +lDl + Gg i++ + tvvA d++ + + ++ + + ++ + + ++ ++ l
tr|A0A1D5NT05|A0A1D5NT05_DANRE 78 FLNIKPGQIVLDLTFGAGGHSKAILQS-VPGVTVVAADRDPTAFRMAQQLAEEYQGK-VKPVLGRFSELNNLLPAlglg 154
7999********************998.67889999999988665544444444444.555666666666655444556 PP
.--EEEEEEEE--CCGG CS
Methyltr_RsmB-F 78 .elfDriLlDaPCsgtg 93
++D +LlDa Cs++
tr|A0A1D5NT05|A0A1D5NT05_DANRE 155 pGTVDAALLDAGCSSMQ 171
699***********876 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (200 nodes)
Target sequences: 25687 (13798380 residues searched)
Passed MSV filter: 1009 (0.0392806); expected 513.7 (0.02)
Passed bias filter: 675 (0.0262779); expected 513.7 (0.02)
Passed Vit filter: 63 (0.0024526); expected 25.7 (0.001)
Passed Fwd filter: 7 (0.000272511); expected 0.3 (1e-05)
Initial search space (Z): 25687 [actual number of targets]
Domain search space (domZ): 7 [number of targets reported over threshold]
# CPU time: 0.23u 0.01s 00:00:00.24 Elapsed: 00:00:00.08
# Mc/sec: 34495.95
//
[ok]