# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/Methyltr_RsmB-F.hmm.txt
# target sequence database:        proteomes/Mus_musculus.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       Methyltr_RsmB-F  [M=200]
Accession:   PF01189.16
Description: 16S rRNA methyltransferase RsmB/F
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
    6.2e-84  280.9   0.0    9.3e-84  280.3   0.0    1.3  1  sp|Q922K7|NOP2_MOUSE    Probable 28S rRNA (cytosine-C(5))-met
    1.2e-45  155.9   0.0    2.4e-45  155.0   0.0    1.5  1  sp|Q7TS68|NSUN6_MOUSE   Putative methyltransferase NSUN6 OS=M
    1.4e-38  132.9   0.0    1.6e-37  129.4   0.0    2.2  1  sp|Q1HFZ0|NSUN2_MOUSE   tRNA (cytosine(34)-C(5))-methyltransf
    3.5e-30  105.4   0.0    5.6e-30  104.8   0.0    1.3  1  sp|Q8K4F6|NSUN5_MOUSE   Probable 28S rRNA (cytosine-C(5))-met
    5.8e-29  101.5   0.0    7.7e-29  101.1   0.0    1.2  1  sp|Q8CCT7|NSUN3_MOUSE   tRNA (cytosine(34)-C(5))-methyltransf
    3.8e-07   30.2   1.0    2.1e-06   27.9   1.0    2.1  1  sp|Q14AW5|NSUN7_MOUSE   Putative methyltransferase NSUN7 OS=M
    3.3e-06   27.2   0.0    5.9e-06   26.4   0.0    1.4  1  sp|Q9DCL4|MET15_MOUSE   Probable methyltransferase-like prote
     0.0016   18.5   0.0     0.0028   17.6   0.0    1.4  1  sp|Q921L7|HEMK1_MOUSE   HemK methyltransferase family member 
  ------ inclusion threshold ------
      0.062   13.2   0.0      0.098   12.6   0.0    1.3  1  tr|Q8BML3|Q8BML3_MOUSE  Glycosyltransferase 28 domain-contain
       0.11   12.5   0.0       0.16   11.9   0.0    1.2  1  sp|Q8K1A0|METL5_MOUSE   Methyltransferase-like protein 5 OS=M
       0.11   12.4   0.0       0.19   11.7   0.0    1.4  1  sp|P35550|FBRL_MOUSE    rRNA 2'-O-methyltransferase fibrillar
       0.13   12.2   0.0       0.24   11.3   0.0    1.5  1  sp|Q80WS3|FBLL1_MOUSE   rRNA/tRNA 2'-O-methyltransferase fibr
       0.14   12.0   0.0       0.34   10.8   0.0    1.6  2  tr|Q8CBC7|Q8CBC7_MOUSE  Putative tRNA (cytidine(32)/guanosine
        0.2   11.6   0.0         20    5.1   0.0    2.2  2  sp|Q91WU5|AS3MT_MOUSE   Arsenite methyltransferase OS=Mus mus


Domain annotation for each sequence (and alignments):
>> sp|Q922K7|NOP2_MOUSE  Probable 28S rRNA (cytosine-C(5))-methyltransferase OS=Mus musculus OX=10090 GN=Nop2 PE=1 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  280.3   0.0   5.9e-87   9.3e-84       1     200 []     362     570 ..     362     570 .. 0.95

  Alignments for each domain:
  == domain 1  score: 280.3 bits;  conditional E-value: 5.9e-87
                           HHHH---TT-EEEECS-TT-HHHHHHHHHTTTTSEEEEEESSCCCHHHHHHHHHHTT--SEEEEES-CCCCHHHHCC--EEEEEEEE-- CS
       Methyltr_RsmB-F   1 allLapqeeetilDlcaaPGgKTthiaelmknkgtvvAvdankeRlkrvaenlkrLgvtntivleaDarkidkvlggelfDriLlDaPC 89 
                           +++Lapqe+e+ilD+c+aPGgKT++ia+lmkn+g+++A+dan+ Rlk+v+ nl+rLgvtnti++++D+r+++kv+gg  fDr+LlDaPC
  sp|Q922K7|NOP2_MOUSE 362 VMALAPQEHERILDMCCAPGGKTSYIAQLMKNTGVILANDANADRLKSVVGNLHRLGVTNTIISHYDGRQFPKVVGG--FDRVLLDAPC 448
                           589*************************************************************************9..********** PP

                           CCGGGTTT-TTHHHH.-CCHHCCHHHHHHHHHHHHHHHE....EEEEEEEEEES---CTCTHHHHHHHHHH-TTEEEESSBSTTSTTSS CS
       Methyltr_RsmB-F  90 sgtgvirrdpdvklrrkekdiaqlaklqkellsaaidll....kkgGvlvYsTCsvlveEneevieeaLkkredvelvetelsepkglk 174
                           sgtgvi++dp+vk++++ekdi+++a+lqkell +aid++    k+gG+lvY+TCs++veEne+v+++aLkkr +v+lv+t l  +++  
  sp|Q922K7|NOP2_MOUSE 449 SGTGVISKDPAVKTNKDEKDIQRCAHLQKELLLSAIDSVnaasKTGGYLVYCTCSITVEENEWVVDYALKKR-NVRLVPTGLDFGQEGF 536
                           ***********************************************************************9.9******665544444 PP

                           ECEEC........T-EEE-TTTTS.-SEEEEEEE CS
       Methyltr_RsmB-F 175 lgeea........gtlrllPhtenkdgffiaklk 200
                           +  +a        +t+r++Pht+n+dgffiak+k
  sp|Q922K7|NOP2_MOUSE 537 TRFQArrfhptlrSTRRFYPHTHNMDGFFIAKFK 570
                           44444899************************96 PP

>> sp|Q7TS68|NSUN6_MOUSE  Putative methyltransferase NSUN6 OS=Mus musculus OX=10090 GN=Nsun6 PE=2 SV=2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  155.0   0.0   1.5e-48   2.4e-45       2     166 ..     228     400 ..     227     464 .. 0.88

  Alignments for each domain:
  == domain 1  score: 155.0 bits;  conditional E-value: 1.5e-48
                            HHH---TT-EEEECS-TT-HHHHHHHHHTTTTSEEEEEESSCCCHHHHHHHHHHTT--SEEEEES-CCCCHHHHCC...........- CS
        Methyltr_RsmB-F   2 llLapqeeetilDlcaaPGgKTthiaelmknkgtvvAvdankeRlkrvaenlkrLgvtntivleaDarkidkvlgg...........e 78 
                             +L+pq++e+ilD+caaPGgKTth a+lm++kg+v+A+d+  ++++++++n + Lg++++  ++ Da+k  k  +            e
  sp|Q7TS68|NSUN6_MOUSE 228 HVLDPQPGEKILDMCAAPGGKTTHTAALMQDKGEVIALDKILTKVNKLKQNASLLGLHSIRAFCFDATKALKLDTTdgieggppflpE 315
                            68*****************************************************************997665444467889****** PP

                            -EEEEEEEE--CCGGGTTT-TTHHHH.-CCHHCCHHHHHHHHHHHHHHHEEEEEEEEEEES---CTCTHHHHHHHHHH-TTEEEESSB CS
        Methyltr_RsmB-F  79 lfDriLlDaPCsgtgvirrdpdvklrrkekdiaqlaklqkellsaaidllkkgGvlvYsTCsvlveEneevieeaLkkredvelvete 166
                             fDri+lDaPCsg+g   ++p++  + + k++++++ lq++ll+ a++llk+gGvlvYsTC+++++Enee+++ aL++ +  +l++ e
  sp|Q7TS68|NSUN6_MOUSE 316 SFDRIILDAPCSGMG---QRPNMACTWTLKEVTSYQPLQRKLLHVAVQLLKPGGVLVYSTCTITLAENEEQVAWALRTFPCLQLQPQE 400
                            *************98...689999999999************************************************9999998875 PP

>> sp|Q1HFZ0|NSUN2_MOUSE  tRNA (cytosine(34)-C(5))-methyltransferase OS=Mus musculus OX=10090 GN=Nsun2 PE=1 SV=2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  129.4   0.0     1e-40   1.6e-37       2     199 ..     170     427 ..     169     428 .. 0.89

  Alignments for each domain:
  == domain 1  score: 129.4 bits;  conditional E-value: 1e-40
                            HHH---TT-EEEECS-TT-HHHHHHHHHTT.......TTSEEEEEESSCCCHHHHHHHHHHTT--SEEEEES-CCCCHHHHCC..... CS
        Methyltr_RsmB-F   2 llLapqeeetilDlcaaPGgKTthiaelmk.......nkgtvvAvdankeRlkrvaenlkrLgvtntivleaDarkidkvlgg..... 77 
                            llL+ +++ +ilD+caaPG+KTt + e+++       ++g v+A+d++++R   +++  krL+   ++v++ Da+ i++ + +     
  sp|Q1HFZ0|NSUN2_MOUSE 170 LLLNVEPHHKILDMCAAPGSKTTQLIEMLHadmsvpfPEGFVIANDVDNKRCYLLVHQAKRLSSPCIMVVNHDASSIPRLTVDvdgrk 257
                            58999**********************976222233347899************************************9998888899 PP

                            ..--EEEEEEEE--CCGGGTTT-TTHHHH.-CCHHCCHHHHHHHHHHHHHHHEEEEEEEEEEES---CTCTHHHHHHHHHH-T.TEEE CS
        Methyltr_RsmB-F  78 ..elfDriLlDaPCsgtgvirrdpdvklrrkekdiaqlaklqkellsaaidllkkgGvlvYsTCsvlveEneevieeaLkkre.dvel 162
                               ++DriL D+PCsg g++r++ dv  + +  +  ql+ lq ++ +  +++l +gG +vYsTCs+++ E+e+vi+++L+k e   el
  sp|Q1HFZ0|NSUN2_MOUSE 258 eiLFYDRILCDVPCSGDGTMRKNIDVWKKWTTLNSLQLHGLQLRIATRGAEQLAEGGRMVYSTCSLNPVEDEAVIAALLEKSEgALEL 345
                            87789*********************6666888999*******************************************998724577 PP

                            ESSBSTTS.TTSSECEEC............................................T-EEE-TTTTS.-SEEEEEE CS
        Methyltr_RsmB-F 163 vetelsep.kglklgeea............................................gtlrllPhtenkdgffiakl 199
                             +++++ p  +   g+ +                                              lr+lPh++n+ gff+a l
  sp|Q1HFZ0|NSUN2_MOUSE 346 ADVSAELPgLKWMPGVSQwkvmtrdgqwfadwhevpqgrhtqirptmfpptdleklqamhleRCLRILPHHQNTGGFFVAVL 427
                            77744432134445555599999*************************************9999***************987 PP

>> sp|Q8K4F6|NSUN5_MOUSE  Probable 28S rRNA (cytosine-C(5))-methyltransferase OS=Mus musculus OX=10090 GN=Nsun5 PE=2 SV=
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  104.8   0.0   3.5e-33   5.6e-30       1     199 [.     219     422 ..     219     423 .. 0.81

  Alignments for each domain:
  == domain 1  score: 104.8 bits;  conditional E-value: 3.5e-33
                            HHHH---TT-EEEECS-TT-HHHHHHHHHTTTTSEEEEEESSCCCHHHHHHHHHHTT--SEEEEES-CCCCHHHHCC.--EEEEEEEE CS
        Methyltr_RsmB-F   1 allLapqeeetilDlcaaPGgKTthiaelmknkgtvvAvdankeRlkrvaenlkrLgvtntivleaDarkidkvlgg.elfDriLlDa 87 
                            a+lL p ++ +++D+caaPG KT++ia+l+kn+g+++A d++++Rl ++a+ + r gv    + e D   ++      +++  iLlD 
  sp|Q8K4F6|NSUN5_MOUSE 219 AMLLSPPPGSHVIDACAAPGNKTSYIAALLKNQGKIFAFDQDAKRLAAMATLVARAGVSCCELAEKDFLTVSPSDQRySQVQYILLDP 306
                            689********************************************************99******8766433333478******** PP

                            --CCGGGTTT-TTHHHH.-C..CHHCCHHHHHHHHHHHHHHHEEEEEEEEEEES---CTCTHHHHHHHHHH-T.TEEEESS..BS.TT CS
        Methyltr_RsmB-F  88 PCsgtgvirrdpdvklrrke..kdiaqlaklqkellsaaidllkkgGvlvYsTCsvlveEneevieeaLkkre.dvelvet..el.se 169
                             Csg g+++r+ + + + ++  + +++la  q++ l  a+    +   lvYsTCs+  eEne v++eaL+++    +l ++   + + 
  sp|Q8K4F6|NSUN5_MOUSE 307 SCSGSGMLSRQLEEHGEGTPskERLQALAGFQQRALCHALRF-PSLQRLVYSTCSLCQEENEDVVQEALQHNSgTFRLAPVlpTWpHR 393
                            **********99988776552167899999888777666543.34457*********************9876256787752122122 PP

                            STTSSECEECT-EEE-TTTTS.-SEEEEEE CS
        Methyltr_RsmB-F 170 pkglklgeeagtlrllPhtenkdgffiakl 199
                            +  +  g e+  lr  P+t  + gffia +
  sp|Q8K4F6|NSUN5_MOUSE 394 GLSTFPGSEH-CLRASPETTLTGGFFIAVF 422
                            2333345555.99**************987 PP

>> sp|Q8CCT7|NSUN3_MOUSE  tRNA (cytosine(34)-C(5))-methyltransferase, mitochondrial OS=Mus musculus OX=10090 GN=Nsun3 PE
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  101.1   0.0   4.8e-32   7.7e-29       2     200 .]     125     332 ..     124     332 .. 0.80

  Alignments for each domain:
  == domain 1  score: 101.1 bits;  conditional E-value: 4.8e-32
                            HHH---TT-EEEECS-TT-HHHHHHHHHTTTTSEEEEEESSCCCHHHHHHHHHHTT--....SEEEEES-CCCCHHHHCC--EEEEEE CS
        Methyltr_RsmB-F   2 llLapqeeetilDlcaaPGgKTthiaelmknkgtvvAvdankeRlkrvaenlkrLgvt....ntivleaDarkidkvlggelfDriLl 85 
                            l+L+++++e +lDlcaaPGgK   +++  +  g ++ ++ ++ R + + ++l+ +  +     ++v+e D+r++ +    ++fD++L+
  sp|Q8CCT7|NSUN3_MOUSE 125 LALELRDGEAVLDLCAAPGGKSVALLQC-AYPGYLLCNEYDRPRGRWLRQTLESFIPQplinVIKVSELDGREMGDAQP-ATFDKVLV 210
                            789************************9.999*******************9997544344367899*******77766.69****** PP

                            EE--CCGG.GTTT-TTHHHH.-CCHHCCHHHHHHHHHHHHHHHEEEEEEEEEEES---CTCTHHHHHHHHHH-TTEEEESSBSTTSTT CS
        Methyltr_RsmB-F  86 DaPCsgtg.virrdpdvklrrkekdiaqlaklqkellsaaidllkkgGvlvYsTCsvlveEneevieeaLkkredvelvetelsepkg 172
                            DaPCs     +    + k   + ++ ++l  lq el+ +ai+ l++gG lvYsTC++  +En+ vi e+L +  ++  v++  s+   
  sp|Q8CCT7|NSUN3_MOUSE 211 DAPCSNDRsWLFSSDSQKAAYRIHQRKNLPVLQVELVRSAIKALRPGGLLVYSTCTLSKAENQDVISEVLTSDSNIVPVDI--SG-IA 295
                            *****86515666667778888888899******************************************99876554443..22.22 PP

                            SSECEEC........T-EEE-TTTTS..-SEEEEEEE CS
        Methyltr_RsmB-F 173 lklgeea........gtlrllPhtenk.dgffiaklk 200
                             +++++           l ++P++ +   +++iaklk
  sp|Q8CCT7|NSUN3_MOUSE 296 RTFSQDFtfaptdqkCSLLVIPEKGKAwGPMYIAKLK 332
                            2222222233344447888899886542679999986 PP

>> sp|Q14AW5|NSUN7_MOUSE  Putative methyltransferase NSUN7 OS=Mus musculus OX=10090 GN=Nsun7 PE=2 SV=2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.9   1.0   1.3e-09   2.1e-06      51     157 ..     342     462 ..     311     478 .. 0.67

  Alignments for each domain:
  == domain 1  score: 27.9 bits;  conditional E-value: 1.3e-09
                            HHHHHTT--SEEEEES-CCCCHHHHCC.--EEEEEEEE--CCGGG.......TTT-TTHHHH.-......CCH.HCCHHHHHHHHHHH CS
        Methyltr_RsmB-F  51 enlkrLgvtntivleaDarkidkvlgg.elfDriLlDaPCsgtgv.......irrdpdvklrrk......ekd.iaqlaklqkellsa 123
                            +  +r+g++n+ +l+     i++     + +  iLl   Cs++gv       ++ ++d  l+++      +kd + +l+++q e l+ 
  sp|Q14AW5|NSUN7_MOUSE 342 KLFTRMGCQNIEILHETFLSIESKDHRlQNVKVILLLPRCSSLGVsnpvefiLNEHEDKSLLQDlsqgglPKDkLETLVQQQFEQLTH 429
                            4568999999999998877776555544778888888889999982222222334444444443222233333256677777788888 PP

                            HHHHEEEEEEEEEEES---CTCTHHHHHHHHHH- CS
        Methyltr_RsmB-F 124 aidllkkgGvlvYsTCsvlveEneevieeaLkkr 157
                            a++ +k +  +vY+TCsv  eEne v+e+aL+ +
  sp|Q14AW5|NSUN7_MOUSE 430 AMKFTKVQ-AIVYCTCSVSKEENEDVVEKALEYQ 462
                            88877876.79********************865 PP

>> sp|Q9DCL4|MET15_MOUSE  Probable methyltransferase-like protein 15 OS=Mus musculus OX=10090 GN=Mettl15 PE=1 SV=2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.4   0.0   3.7e-09   5.9e-06       2      92 ..      82     175 ..      81     189 .. 0.92

  Alignments for each domain:
  == domain 1  score: 26.4 bits;  conditional E-value: 3.7e-09
                            HHH---TT-EEEECS-TT-HHHHHHHHHTTTTSEEEEEESSCCCHHHHHHHHHHTT--SEEEEES-CCCCHHHHCC.....--EEEEE CS
        Methyltr_RsmB-F   2 llLapqeeetilDlcaaPGgKTthiaelmknkgtvvAvdankeRlkrvaenlkrLgvtntivleaDarkidkvlgg.....elfDriL 84 
                             +Lapq+++ +lD+  + Gg T  i++  ++   v+A+d++   + ++ae l+rL  t+++ l +  ++ +  l +      ++D iL
  sp|Q9DCL4|MET15_MOUSE  82 HCLAPQKGQVFLDMTFGSGGHTRAILQK-EPDVMVYALDRDPV-AYAIAEQLSRLYPTQIQALLGQFSQAEALLMKagvqpGTIDGIL 167
                            579************************8.9999*******987.679***********************9999888888889***** PP

                            EEE--CCG CS
        Methyltr_RsmB-F  85 lDaPCsgt 92 
                            +D  Cs++
  sp|Q9DCL4|MET15_MOUSE 168 MDLGCSSM 175
                            ******86 PP

>> sp|Q921L7|HEMK1_MOUSE  HemK methyltransferase family member 1 OS=Mus musculus OX=10090 GN=Hemk1 PE=2 SV=2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.6   0.0   1.7e-06    0.0028       5      69 ..     157     221 ..     153     228 .. 0.87

  Alignments for each domain:
  == domain 1  score: 17.6 bits;  conditional E-value: 1.7e-06
                            ---TT-EEEECS-TT-HHH.HHHHHHTTTTSEEEEEESSCCCHHHHHHHHHHTT--.SEEEEES-CC CS
        Methyltr_RsmB-F   5 apqeeetilDlcaaPGgKT.thiaelmknkgtvvAvdankeRlkrvaenlkrLgvt.ntivleaDar 69 
                              q++  il++ ++ G+ T +++++l  +k++vvAvd+++  ++  +en +rL ++  + +++ D++
  sp|Q921L7|HEMK1_MOUSE 157 RAQDGPLILEVGCGSGAITlSLLSQL--PKSRVVAVDKEEAAVSLTHENAQRLQLQdRIRIIHLDIT 221
                            5688889**********995667777..999************************967889999986 PP

>> tr|Q8BML3|Q8BML3_MOUSE  Glycosyltransferase 28 domain-containing 2 OS=Mus musculus OX=10090 GN=Glt28d2 PE=1 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.0   6.2e-05     0.098     125     144 ..     113     132 ..      98     138 .. 0.86

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 6.2e-05
                             HHHEEEEEEEEEEES---CT CS
         Methyltr_RsmB-F 125 idllkkgGvlvYsTCsvlve 144
                             +++l+k+G l Y+TCs+l+e
  tr|Q8BML3|Q8BML3_MOUSE 113 AKQLHKEGHLFYCTCSMLPE 132
                             577899***********997 PP

>> sp|Q8K1A0|METL5_MOUSE  Methyltransferase-like protein 5 OS=Mus musculus OX=10090 GN=Mettl5 PE=2 SV=2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   9.7e-05      0.16      29      88 ..      70     128 ..      47     145 .. 0.83

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 9.7e-05
                            HTTTTSEEEEEESSCCCHHHHHHHHHHTT--SEEEEES-CCCCHHHHCC--EEEEEEEE- CS
        Methyltr_RsmB-F  29 lmknkgtvvAvdankeRlkrvaenlkrLgvtntivleaDarkidkvlggelfDriLlDaP 88 
                             m  +g  v  d+++  l+  ++n++ + +tn+ +++ D+   ++ +++ lfD +++  P
  sp|Q8K1A0|METL5_MOUSE  70 AMLGAGLCVGFDIDEDALEIFNKNVEEFELTNVDMIQCDVYSLSNRMSK-LFDTVIMNPP 128
                            45567888999************************************96.******9988 PP

>> sp|P35550|FBRL_MOUSE  rRNA 2'-O-methyltransferase fibrillarin OS=Mus musculus OX=10090 GN=Fbl PE=1 SV=2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   0.00012      0.19       7      87 ..     164     243 ..     159     267 .. 0.81

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 0.00012
                           -TT-EEEECS-TT-HHHHHHHHHTTTTSEEEEEESSCCCHHHHHHHHHHTT--SEEEEES-CCCCHHHHCC.--EEEEEEEE CS
       Methyltr_RsmB-F   7 qeeetilDlcaaPGgKTthiaelmknkgtvvAvdankeRlkrvaenlkrLgvtntivleaDarkidkvlgg.elfDriLlDa 87 
                           +++ ++l l aa G   +h+++++ + g v+Av+ +++  + ++ nl +   tn+i +  Dar+++k+    +++D i  D+
  sp|P35550|FBRL_MOUSE 164 KPGAKVLYLGAASGTTVSHVSDIVGPDGLVYAVEFSHRSGRDLI-NLAKK-RTNIIPVIEDARHPHKYRMLiAMVDVIFADV 243
                           567789999*************************9866555554.44443.3457788899999999866547788777775 PP

>> sp|Q80WS3|FBLL1_MOUSE  rRNA/tRNA 2'-O-methyltransferase fibrillarin-like protein 1 OS=Mus musculus OX=10090 GN=Fbll1 
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.0   0.00015      0.24       7      86 ..     152     230 ..     147     242 .. 0.75

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 0.00015
                            -TT-EEEECS-TT-HHHHHHHHHTTTTSEEEEEESSCCCHHHHHHHHHHTT--SEEEEES-CCCCHHHHCC.--EEEEEEE CS
        Methyltr_RsmB-F   7 qeeetilDlcaaPGgKTthiaelmknkgtvvAvdankeRlkrvaenlkrLgvtntivleaDarkidkvlgg.elfDriLlD 86 
                            +++ ++l l aa G   +h+++++ + g v+Av+ ++ R+ r   n+ +   tn+i +  Dar++ k+     ++D i  D
  sp|Q80WS3|FBLL1_MOUSE 152 KPKSKVLYLGAASGTTVSHVSDIIGPDGLVYAVEFSH-RAGRDLVNVAKKR-TNIIPVLEDARHPLKYRMLiGMVDVIFAD 230
                            56778999**************************975.5555445555433.45778888999887664332456666555 PP

>> tr|Q8CBC7|Q8CBC7_MOUSE  Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase OS=Mus musculus OX=10090 GN
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.0   0.00021      0.34      11      44 ..      44      79 ..      39     120 .. 0.75
   2 ?   -2.4   0.0       2.5   3.9e+03     109     134 ..     126     153 ..     108     154 .. 0.64

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.00021
                            EEEECS-TT-HHHHHHHHH..TTTTSEEEEEESSCC CS
         Methyltr_RsmB-F 11 tilDlcaaPGgKTthiael..mknkgtvvAvdanke 44
                            + +DlcaaPG+    +++    + +g+vvAvd ++ 
  tr|Q8CBC7|Q8CBC7_MOUSE 44 RAVDLCAAPGSWSQVLSQKvgGQGSGQVVAVDLQAM 79
                            568*************99834466789*****8764 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 2.5
                             HHCCHHHHHHHH..HHHHHHHEEEEEEE CS
         Methyltr_RsmB-F 109 diaqlaklqkel..lsaaidllkkgGvl 134
                             d+ ++++ q  l  l++a ++lk gG  
  tr|Q8CBC7|Q8CBC7_MOUSE 126 DVDEYMQAQLLLaaLNIATHVLKLGGCF 153
                             4444444443322266777778999876 PP

>> sp|Q91WU5|AS3MT_MOUSE  Arsenite methyltransferase OS=Mus musculus OX=10090 GN=As3mt PE=1 SV=2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.3   0.0     0.021        34       8      47 ..      71     110 ..      65     153 .. 0.83
   2 ?    5.1   0.0     0.012        20     110     145 ..     158     195 ..     151     202 .. 0.79

  Alignments for each domain:
  == domain 1  score: 4.3 bits;  conditional E-value: 0.021
                            TT-EEEECS-TT-HHHHHHHHHTTTTSEEEEEESSCCCHH CS
        Methyltr_RsmB-F   8 eeetilDlcaaPGgKTthiaelmknkgtvvAvdankeRlk 47 
                            e+ +ilDl ++ G     +++l+ +kg+v+ +d+ +  ++
  sp|Q91WU5|AS3MT_MOUSE  71 ENCRILDLGSGSGRDCYVLSQLVGEKGHVTGIDMTEVQVE 110
                            5678*****************************9887665 PP

  == domain 2  score: 5.1 bits;  conditional E-value: 0.012
                            HCCHHHHHHHHHHHHHHHEEEEEEEEEEE..S---CTC CS
        Methyltr_RsmB-F 110 iaqlaklqkellsaaidllkkgGvlvYsT..CsvlveE 145
                            +++l+  ++++l+ +  +lk+gG l +s    s++v E
  sp|Q91WU5|AS3MT_MOUSE 158 VINLVPDKQQVLQEVYRVLKHGGELYFSDvyASLEVPE 195
                            67788899*****************9885223555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (200 nodes)
Target sequences:                        22289  (11757923 residues searched)
Passed MSV filter:                       765  (0.0343219); expected 445.8 (0.02)
Passed bias filter:                      516  (0.0231504); expected 445.8 (0.02)
Passed Vit filter:                        50  (0.00224326); expected 22.3 (0.001)
Passed Fwd filter:                        14  (0.000628113); expected 0.2 (1e-05)
Initial search space (Z):              22289  [actual number of targets]
Domain search space  (domZ):              14  [number of targets reported over threshold]
# CPU time: 0.22u 0.01s 00:00:00.23 Elapsed: 00:00:00.08
# Mc/sec: 29394.81
//
[ok]