# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/Methyltr_RsmB-F.hmm.txt # target sequence database: proteomes/Trypanosoma_brucei.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: Methyltr_RsmB-F [M=200] Accession: PF01189.16 Description: 16S rRNA methyltransferase RsmB/F Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-69 232.9 0.0 2.2e-69 232.1 0.0 1.4 1 tr|Q583H8|Q583H8_TRYB2 Nucleolar protein, putative OS=Trypan 3.7e-38 130.1 0.1 1.7e-35 121.4 0.0 2.2 2 tr|Q57V63|Q57V63_TRYB2 Uncharacterized protein OS=Trypanosom 3.9e-33 113.7 0.0 1e-32 112.4 0.0 1.7 2 tr|Q388U8|Q388U8_TRYB2 Methyltransferase, putative OS=Trypan 2.6e-29 101.3 0.0 5.2e-22 77.4 0.0 3.2 2 tr|Q38AT8|Q38AT8_TRYB2 Uncharacterized protein OS=Trypanosom 5.6e-29 100.2 0.0 3.7e-27 94.2 0.0 3.3 2 tr|Q582C3|Q582C3_TRYB2 Uncharacterized protein OS=Trypanosom 1.1e-28 99.2 0.0 1.5e-28 98.7 0.0 1.1 1 tr|Q381M3|Q381M3_TRYB2 Uncharacterized protein OS=Trypanosom 2.6e-28 98.0 0.1 1.8e-16 59.3 0.2 2.3 2 tr|Q384A7|Q384A7_TRYB2 Uncharacterized protein OS=Trypanosom 3.6e-21 74.7 0.1 2.1e-08 33.0 0.0 3.4 3 tr|Q580I8|Q580I8_TRYB2 Uncharacterized protein OS=Trypanosom 0.00085 18.0 0.0 0.0016 17.0 0.0 1.4 1 tr|Q388E0|Q388E0_TRYB2 Fibrillarin, putative OS=Trypanosoma 0.0016 17.0 0.0 0.003 16.2 0.0 1.3 1 tr|Q388C9|Q388C9_TRYB2 Fibrillarin, putative OS=Trypanosoma 0.004 15.8 0.0 0.0086 14.7 0.0 1.5 1 tr|Q381D3|Q381D3_TRYB2 Uncharacterized protein OS=Trypanosom 0.0096 14.5 0.0 0.019 13.6 0.0 1.4 1 tr|Q38AL4|Q38AL4_TRYB2 Fibrillarin OS=Trypanosoma brucei bru Domain annotation for each sequence (and alignments): >> tr|Q583H8|Q583H8_TRYB2 Nucleolar protein, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 G # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 232.1 0.0 3e-72 2.2e-69 1 200 [] 249 453 .. 249 453 .. 0.92 Alignments for each domain: == domain 1 score: 232.1 bits; conditional E-value: 3e-72 HHHH---TT-EEEECS-TT-HHHHHHHHHTTTTSEEEEEESSCCCHHHHHHHHHHTT--SEEEEES-CCCCHHHHCC--EEEEEEEE CS Methyltr_RsmB-F 1 allLapqeeetilDlcaaPGgKTthiaelmknkgtvvAvdankeRlkrvaenlkrLgvtntivleaDarkidkvlggelfDriLlDa 87 +++Lapq +e++lD++aaPGgKTt+ia+lmkn+g+++A+d+++ R+k++++nl+rLgvtnt v+++D+ ++kv+ + fDriLlDa tr|Q583H8|Q583H8_TRYB2 249 VMALAPQINERVLDMAAAPGGKTTYIAQLMKNTGVIFANDVSEPRTKSLNANLQRLGVTNTVVTNYDGVGFEKVMKN--FDRILLDA 333 589***********************************************************************997..******** PP --CCGGGTTT-TTHHHH.-CCHHCCHHHHHHHHHHHHHHHEEEEEEEEEEES---CTCTHHHHHHHHHH-TTEEEESSBST..TSTT CS Methyltr_RsmB-F 88 PCsgtgvirrdpdvklrrkekdiaqlaklqkellsaaidllkkgGvlvYsTCsvlveEneevieeaLkkredvelvetels..epkg 172 PC+g g+i+rd+++k++++ +d+++ ++lq+ ll +aid ++ gG++vYsTCs lveEne+v++ +L++r dv++vet l p tr|Q583H8|Q583H8_TRYB2 334 PCTGSGIISRDKSIKTSKQYEDVQRASQLQRSLLLSAIDAVRVGGYIVYSTCSFLVEENEAVVDFVLHRR-DVAIVETGLPfgRPGL 419 ********************************************************************99.7777777654113333 PP SSECEEC......T-EEE-TTTTS.-SEEEEEEE CS Methyltr_RsmB-F 173 lklgeea......gtlrllPhtenkdgffiaklk 200 +k+ ++ +++rl+Ph +n+dgff+ klk tr|Q583H8|Q583H8_TRYB2 420 TKYRHHRfhdklqNARRLFPHVHNMDGFFVCKLK 453 334333388888899****************996 PP >> tr|Q57V63|Q57V63_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 121.4 0.0 2.4e-38 1.7e-35 2 157 .. 146 306 .. 145 325 .. 0.90 2 ! 6.7 0.0 0.0034 2.4 179 199 .. 371 399 .. 327 400 .. 0.69 Alignments for each domain: == domain 1 score: 121.4 bits; conditional E-value: 2.4e-38 HHH---TT-EEEECS-TT-HHHHHHHHH...TTTTSEEEEEESSCCCHHHHHHHHHHTT--..SEEEEES-CCCCHHHHCC--EEEE CS Methyltr_RsmB-F 2 llLapqeeetilDlcaaPGgKTthiael...mknkgtvvAvdankeRlkrvaenlkrLgvt..ntivleaDarkidkvlggelfDri 83 +lL+ +++++lD+caaPG+KT+ i+e ++ g+vvA+d n Rl+ + + + r + ++iv+++D+++++ +++fDr+ tr|Q57V63|Q57V63_TRYB2 146 VLLQVAPGNRVLDMCAAPGSKTSQILEAvisSNQDGVVVANDLNVARLDVLLHQTARSPGAhpHLIVTNYDGTQFPLLPKEDKFDRV 232 6899999******************997444567899*************99999888665479*********************** PP EEEE--CCGGGTTT-TTHHHH.-CCHHCCHHHHHHHHHHHHHHHEEEEEEEEEEES---CTCTHHHHHHHHHH- CS Methyltr_RsmB-F 84 LlDaPCsgtgvirrdpdvklrrkekdiaqlaklqkellsaaidllkkgGvlvYsTCsvlveEneevieeaLkkr 157 L D+ Csg g++r+ d+ r + a l+ q ++l+ + l kkgG++vYsTCs+++ E+e+v+ e L++ tr|Q57V63|Q57V63_TRYB2 233 LCDVMCSGDGTLRKSMDMWPRWNTVHGADLHVTQVRVLTRGMMLCKKGGIVVYSTCSLNPVEDEAVVSECLSQA 306 ******************55566677899*****************************************9875 PP == domain 2 score: 6.7 bits; conditional E-value: 0.0034 C........T-EEE-TTTTS.-SEEEEEE CS Methyltr_RsmB-F 179 a........gtlrllPhtenkdgffiakl 199 + ++r++Ph++++ gff a++ tr|Q57V63|Q57V63_TRYB2 371 QvlreqnihFARRVVPHQQDTGGFFFAAM 399 033333344789**************986 PP >> tr|Q388U8|Q388U8_TRYB2 Methyltransferase, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 G # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 112.4 0.0 1.4e-35 1e-32 6 200 .] 262 500 .. 257 500 .. 0.85 2 ? -3.1 0.0 3.4 2.4e+03 24 72 .. 651 700 .. 649 706 .. 0.72 Alignments for each domain: == domain 1 score: 112.4 bits; conditional E-value: 1.4e-35 --TT-EEEECS-TT-HHHHH.HHHHTTT........TSEEEEEESSCCC.HHHHHHHHHHTT--SEEEEES-CCCCHHHHCC..... CS Methyltr_RsmB-F 6 pqeeetilDlcaaPGgKTth.iaelmkn........kgtvvAvdankeR.lkrvaenlkrLgvtntivleaDarkidkvlgg..... 77 q++ t+lD+caaPG+KT + e++kn +g++vA+++++ + ++ + + lkr n+i+++ Da + ++ l tr|Q388U8|Q388U8_TRYB2 262 IQPHHTVLDMCAAPGSKTLQaLDEMLKNgwnssavsSGVMVANEKDRVKaTQTLPARLKRYHAPNVICTRCDAVQWPRLLCPttqgd 348 57899*************7526678776333333335677888887755256788999999999*********99988776556677 PP .....--EEEEEEEE--CCGGGTTT-TTHHHH.-CCHHCCHHHHHHHHHHHHHHHEEEEEEEEEEES---CTCTHHHHHHHHHH-.T CS Methyltr_RsmB-F 78 .....elfDriLlDaPCsgtgvirrdpdvklrrkekdiaqlaklqkellsaaidllkkgGvlvYsTCsvlveEneevieeaLkkr.e 158 + fDr++ D+PCsg g++r++p++ + + +++l q++ll +dll ++G+lvYsTCs++++E+eev+ + L+ + tr|Q388U8|Q388U8_TRYB2 349 mhlgeRRFDRVICDVPCSGDGTLRKEPSLASSWSAGYVKSLLPTQRALLRRGLDLLETDGILVYSTCSLQPKEDEEVVCAGLELFgD 435 888889****************************************************************************97625 PP TEEEESSBSTTSTTSSECEEC..........................T-EEE-TTTTS.-SEEEEEEE CS Methyltr_RsmB-F 159 dvelvetelsepkglklgeea..........................gtlrllPhtenkdgffiaklk 200 vel +++ + ++g++ + lr+lPh++++ gffia+++ tr|Q388U8|Q388U8_TRYB2 436 AVELLDVS---SILRECGVQLhsfggllspdtthlrnsvlpnsydgrKVLRVLPHKDDTGGFFIAAFR 500 67888873...3345555555567899*******************999****************985 PP == domain 2 score: -3.1 bits; conditional E-value: 3.4 HHHHHHTTTTSEEEEEESSCCCHHHHHHH.HHHTT--SEEEEES-CCCCH CS Methyltr_RsmB-F 24 thiaelmknkgtvvAvdankeRlkrvaen.lkrLgvtntivleaDarkid 72 ++++ + + ++ v+ d++ + +k + +n L + vl+ Da+ +d tr|Q388U8|Q388U8_TRYB2 651 SYLSSIAHARKIVINADHHPQVVKDLLSNgFVWLHEQWRCVLCQDASTTD 700 78999988999999999999999988877234555555666666766665 PP >> tr|Q38AT8|Q38AT8_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.9 0.0 3.1e-07 0.00022 3 31 .. 164 192 .. 162 204 .. 0.81 2 ! 77.4 0.0 7.3e-25 5.2e-22 32 199 .. 212 446 .. 210 447 .. 0.84 Alignments for each domain: == domain 1 score: 19.9 bits; conditional E-value: 3.1e-07 HH---TT-EEEECS-TT-HHHHHHHHHTT CS Methyltr_RsmB-F 3 lLapqeeetilDlcaaPGgKTthiaelmk 31 lL+ q+ ++ lD+ca+PG+KT+ i+ + tr|Q38AT8|Q38AT8_TRYB2 164 LLDIQPTDKCLDMCASPGSKTAQILVSLG 192 7999******************9985544 PP == domain 2 score: 77.4 bits; conditional E-value: 7.3e-25 TTSEEEEEESSCCCHHHHHHHHHHTT--..SEEEEES-CCCCHHHHCC.....................--EEEEEEEE--CCGGGT CS Methyltr_RsmB-F 32 nkgtvvAvdankeRlkrvaenlkrLgvt..ntivleaDarkidkvlgg.....................elfDriLlDaPCsgtgvi 95 ++g vvA+d++++R++ +++ +kr+ + + ++ Da+ +++++ fD+iL D+ Csg g+i tr|Q38AT8|Q38AT8_TRYB2 212 SEGLVVANDIDTKRANMLVHQVKRMRLLfpFALFTNHDAQFFPNMVLTpgeaqphtcgqqttgddgateLRFDKILCDVVCSGDGTI 298 5789********************999866788999*******999888889**************99889**************** PP TT-TTHHHH.-CCHHCCHHHHHHHHHHHHHHHEEEEEEEEEEES---CTCTHHHHHHHHHH-T.TEEEESSB.STTSTTSSECEEC. CS Methyltr_RsmB-F 96 rrdpdvklrrkekdiaqlaklqkellsaaidllkkgGvlvYsTCsvlveEneevieeaLkkre.dvelvete.lsepkglklgeea. 179 r+ p++ ++++ ++l+k q ++ a +ll+ gG lvYsTCs+++ Ene+v+++++++++ ++l++ + l + + + g ++ tr|Q38AT8|Q38AT8_TRYB2 299 RKAPHILKMWSPREAISLQKVQIQIALRACHLLRVGGRLVYSTCSMNPIENEAVVAQIIHRTKgAMKLIDCSsLLPGLRFTPGLQKw 385 *******9*************************************************998765156676654123344555555557 PP .........................................T-EEE-TTTTS.-SEEEEEE CS Methyltr_RsmB-F 180 .........................................gtlrllPhtenkdgffiakl 199 lrllP + n +ffia l tr|Q38AT8|Q38AT8_TRYB2 386 vvtnskgnvveapcqeahealfppgtpgayssdavdamdlrLCLRLLPSHCNGGAFFIAVL 446 7777777788888888888888888888888888777777777777787777777877765 PP >> tr|Q582C3|Q582C3_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.8 0.0 0.67 4.8e+02 136 176 .. 106 144 .. 86 161 .. 0.77 2 ! 94.2 0.0 5.2e-30 3.7e-27 2 199 .. 304 567 .. 303 568 .. 0.76 Alignments for each domain: == domain 1 score: -0.8 bits; conditional E-value: 0.67 EEES---CTCTHHHHHHHHHH-TTEEEESSBSTTSTTSSEC CS Methyltr_RsmB-F 136 YsTCsvlveEneevieeaLkkredvelvetelsepkglklg 176 ++TC+ +++ vie++++k +d + ++ e++ + ++ + tr|Q582C3|Q582C3_TRYB2 106 FATCTN--ADEMRVIEQIIQKFHDKQCTDGETKRGLSQQHQ 144 688874..567899999999999998888877765555444 PP == domain 2 score: 94.2 bits; conditional E-value: 5.2e-30 HHH---TT-EEEECS-TT-HHHHHHHHHTT..............TTSEEEEEESSCCCHHHHHHHHHHTT--SEEEEES-CCCCHHH CS Methyltr_RsmB-F 2 llLapqeeetilDlcaaPGgKTthiaelmk..............nkgtvvAvdankeRlkrvaenlkrLgvtntivleaDarkidkv 74 llL+p++++ +lDlca+PG KT+++++ ++ ++g++vA+d++ R +++a+ l+ + t + v++ ++ + tr|Q582C3|Q582C3_TRYB2 304 LLLDPRPGDAVLDLCASPGNKTSLVLDYVSslrstslpssnphfHHGCIVANDVSPPRSRQLAQRLRNSSPT-VAVTQFHGQSLPLE 389 78*********************887643212223333333333579******************9998888.99999999998877 PP HCC...--EEEEEEEE--CCGGGTTT-TTHHHH.-CCHHCCHHHHHHHHHHHHHHHEEEEEEEEEEES---CTCTHHHHHHHHHH-T CS Methyltr_RsmB-F 75 lgg...elfDriLlDaPCsgtgvirrdpdvklrrkekdiaqlaklqkellsaaidllkkgGvlvYsTCsvlveEneevieeaLkkre 158 +g +++ +iL+DaPCsg g ++rd ++ q+++ q +ll a++l gG +vYsTC++++ E+e+vi+++L++ tr|Q582C3|Q582C3_TRYB2 390 TGAsggNKYNKILVDAPCSGEGRMQRDAMSWRMWHPLRGLQFMQTQLRLLRRAVNLCSVGGHIVYSTCTLNPLEDEAVIAAVLRDG- 475 655556********************98775567899999********************************************98. PP TEEEES..SBSTTSTTSSECEEC................................................T-EEE-TTTT.S.-SE CS Methyltr_RsmB-F 159 dvelve..telsepkglklgeea................................................gtlrllPhte.nkdgf 194 velve +el e +g +++++ lr++Ph + +gf tr|Q582C3|Q582C3_TRYB2 476 AVELVEppRELREKSGWRFSRGLrrwvvpsraggflntlaeaeakgegnpttltdlfpyegnekiqsalesCCLRVMPHCNgGAEGF 562 677775125566666666666666666666666666666666666666666666666666666666666666666666654134666 PP EEEEE CS Methyltr_RsmB-F 195 fiakl 199 f+a l tr|Q582C3|Q582C3_TRYB2 563 FVALL 567 66655 PP >> tr|Q381M3|Q381M3_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 98.7 0.0 2.1e-31 1.5e-28 3 189 .. 113 299 .. 111 309 .. 0.85 Alignments for each domain: == domain 1 score: 98.7 bits; conditional E-value: 2.1e-31 HH---TT-EEEECS-TT-HHHHHHHHHTTTTSEEEEEESSCCCHHHHHHHHHHTT--SEEEEES-CCCCHHHHCC--EEEEEEEE-- CS Methyltr_RsmB-F 3 lLapqeeetilDlcaaPGgKTthiaelmknkgtvvAvdankeRlkrvaenlkrLgvtntivleaDarkidkvlggelfDriLlDaPC 89 lL q+ + +lDlca+ GgK i+++++n++ ++A+++ R r+ +n+k n +++ rk++++ +++ r+L+DaPC tr|Q381M3|Q381M3_TRYB2 113 LLGVQQFDLVLDLCAGVGGKSIAISQFLSNSASLTANEQRGDRCARLRRNIKEYVPSNYVPVTVTQRKPETWHDPSTYHRVLVDAPC 199 577788899*********************************************9999*99************************** PP CCGGGTTT-T...TH.HHH.-CCHHCCHHHHHHHHHHHHHHHEEEEEEEEEEES---CTCTHHHHHHHHHH.-TTEEEESSBSTTST CS Methyltr_RsmB-F 90 sgtgvirrdp...dv.klrrkekdiaqlaklqkellsaaidllkkgGvlvYsTCsvlveEneevieeaLkk.redvelvetelsepk 171 +g + ++ +v l+ + + +l++ q+ ll i++ ++gG +vY+TCs+ + En ev+ eaLk+ r +vel++ ++ ++ tr|Q381M3|Q381M3_TRYB2 200 TGERQLLQHSgkhAVsPLHWSLQACVELSHTQRGLLLRSIETCRPGGRIVYTTCSISPLENDEVVREALKRtRCQVELMHPPVPIGE 286 **987766541112313445667889999****************************************872568888888777666 PP TSSECEECT-EEE-TTTT CS Methyltr_RsmB-F 172 glklgeeagtlrllPhte 189 ++++g+ lP+++ tr|Q381M3|Q381M3_TRYB2 287 KTEFGHIV-----LPDRD 299 66666544.....55555 PP >> tr|Q384A7|Q384A7_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 59.3 0.2 2.5e-19 1.8e-16 10 103 .. 304 396 .. 298 404 .. 0.89 2 ! 36.2 0.0 3.2e-12 2.3e-09 107 199 .. 449 551 .. 434 552 .. 0.77 Alignments for each domain: == domain 1 score: 59.3 bits; conditional E-value: 2.5e-19 -EEEECS-TT-HHHHHHHHHTTTTSEEEEEESSCCCHHHHHHHHHHTT--.SEEEEES-CCCCHHHHCC--EEEEEEEE--CCGGGT CS Methyltr_RsmB-F 10 etilDlcaaPGgKTthiaelmknkgtvvAvdankeRlkrvaenlkrLgvt.ntivleaDarkidkvlggelfDriLlDaPCsgtgvi 95 e ++D+caaPG KTt +a+l +++ +++A++++++R++ + + ++ Lg t v+++D k+ ++ + + + iLlD Cs+ gv+ tr|Q384A7|Q384A7_TRYB2 304 EYVVDACAAPGNKTTQLAALGAPHVKIMAIERDDKRAELLRHRVQSLGAAdYTNVVNMDFLKMAQDDRE-VTEGILLDPSCSASGVL 389 789*********************************************985799*********999885.99*************** PP TT-TTHHH CS Methyltr_RsmB-F 96 rrdpdvkl 103 r + l tr|Q384A7|Q384A7_TRYB2 390 TRVDVA-L 396 996433.4 PP == domain 2 score: 36.2 bits; conditional E-value: 3.2e-12 CCHHCCHHHHHHHHHHHHHHHEEEEEEEEEEES---CTCTHHHHHHHHHH-TTEEEESSBSTTSTTSSECEEC...........T-E CS Methyltr_RsmB-F 107 ekdiaqlaklqkellsaaidllkkgGvlvYsTCsvlveEneevieeaLkkredvelvetelsepkglklgeea...........gtl 182 + ++ la+lq++ll + + + ++vYsTCsv+ +Eneev+ ++L+++ + ls+ ++ + t+ tr|Q384A7|Q384A7_TRYB2 449 MERVMGLARLQRKLLAHSLLSFDNCRTVVYSTCSVHEAENEEVVRQVLQDERV-QARGWALSNIMPTTWRTRGwrndsdtfpleYTI 534 56688899*****************************************8743.333333333222222222234455778998999 PP EE-TTTTS.-SEEEEEE CS Methyltr_RsmB-F 183 rllPhtenkdgffiakl 199 r P+ + ++gff+a++ tr|Q384A7|Q384A7_TRYB2 535 RCDPEVDATNGFFVARF 551 ***************87 PP >> tr|Q580I8|Q580I8_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.0 0.0 9.8e-10 7e-07 2 72 .. 129 199 .. 128 208 .. 0.93 2 ! 9.6 0.0 0.00045 0.32 78 95 .. 282 299 .. 256 302 .. 0.74 3 ! 33.0 0.0 2.9e-11 2.1e-08 109 157 .. 352 400 .. 346 415 .. 0.86 Alignments for each domain: == domain 1 score: 28.0 bits; conditional E-value: 9.8e-10 HHH---TT-EEEECS-TT-HHHHHHHHHTTTTSEEEEEESSCCCHHHHHHHHHHTT--SEEEEES-CCCCH CS Methyltr_RsmB-F 2 llLapqeeetilDlcaaPGgKTthiaelmknkgtvvAvdankeRlkrvaenlkrLgvtntivleaDarkid 72 ++L p+ +et+ D+c++PG K ++ia+ + ++g v +d+n Rl + + +k+ +n+ ++ aD++ + tr|Q580I8|Q580I8_TRYB2 129 VALRPRRGETVWDVCCSPGMKLSFIADAIGEEGSAVGTDINLDRLFAARSVMKKHRANNVCLFVADGTSFA 199 789*******************************************9999999999999999999998875 PP == domain 2 score: 9.6 bits; conditional E-value: 0.00045 --EEEEEEEE--CCGGGT CS Methyltr_RsmB-F 78 elfDriLlDaPCsgtgvi 95 fDr+L+Da Cs g + tr|Q580I8|Q580I8_TRYB2 282 YGFDRVLVDAECSHDGSL 299 34***********98865 PP == domain 3 score: 33.0 bits; conditional E-value: 2.9e-11 HHCCHHHHHHHHHHHHHHHEEEEEEEEEEES---CTCTHHHHHHHHHH- CS Methyltr_RsmB-F 109 diaqlaklqkellsaaidllkkgGvlvYsTCsvlveEneevieeaLkkr 157 ++ l++lq +ll+ ++l +gG+lvY+TCs + + ne ++e++++ tr|Q580I8|Q580I8_TRYB2 352 KVSPLQQLQLQLLTNGYAQLNPGGTLVYCTCSFTYQQNEGIVQEMMHSV 400 678899**************************************99865 PP >> tr|Q388E0|Q388E0_TRYB2 Fibrillarin, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb10 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.0 0.0 2.3e-06 0.0016 7 87 .. 67 147 .. 62 156 .. 0.85 Alignments for each domain: == domain 1 score: 17.0 bits; conditional E-value: 2.3e-06 -TT-EEEECS-TT-HHHHHHHHHTTTTSEEEEEESSCCCHHHHHHHHHHTT--SEEEEES-CCCCHHHHCC..--EEEEEEEE CS Methyltr_RsmB-F 7 qeeetilDlcaaPGgKTthiaelmknkgtvvAvdankeRlkrvaenlkrLgvtntivleaDarkidkvlgg..elfDriLlDa 87 +++ t+l l aa G +h+++l+ ++g+v+Av+ +++ + ++e kr + n+ + Dar+++k+ +l+D i +D+ tr|Q388E0|Q388E0_TRYB2 67 EPGSTVLYLGAASGTTVSHVSDLVGPEGVVYAVEFSHRSGRDLEEMSKRRS--NIVPILEDARYPQKYRMLipRLVDCIFMDV 147 567899*****************************9999999999888854..556778899999988765568999999886 PP >> tr|Q388C9|Q388C9_TRYB2 Fibrillarin, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb10 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.2 0.0 4.3e-06 0.003 7 87 .. 143 223 .. 138 229 .. 0.85 Alignments for each domain: == domain 1 score: 16.2 bits; conditional E-value: 4.3e-06 -TT-EEEECS-TT-HHHHHHHHHTTTTSEEEEEESSCCCHHHHHHHHHHTT--SEEEEES-CCCCHHHHCC..--EEEEEEEE CS Methyltr_RsmB-F 7 qeeetilDlcaaPGgKTthiaelmknkgtvvAvdankeRlkrvaenlkrLgvtntivleaDarkidkvlgg..elfDriLlDa 87 +++ t+l l aa G +h+++l+ ++g+v+Av+ +++ + ++e kr + n+ + Dar+++k+ +l+D i +D+ tr|Q388C9|Q388C9_TRYB2 143 EPGSTVLYLGAASGTTVSHVSDLVGPEGVVYAVEFSHRSGRDLEEMSKRRS--NIVPILEDARYPQKYRMLipRLVDCIFMDV 223 567899*****************************9999999999888854..456778899999988665568899998886 PP >> tr|Q381D3|Q381D3_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.7 0.0 1.2e-05 0.0086 114 157 .. 531 574 .. 522 586 .. 0.87 Alignments for each domain: == domain 1 score: 14.7 bits; conditional E-value: 1.2e-05 HHHHHHHHHHHHHHEEEEEEEEEEES---CTCTHHHHHHHHHH- CS Methyltr_RsmB-F 114 aklqkellsaaidllkkgGvlvYsTCsvlveEneevieeaLkkr 157 + l++el++a+ + G +vY+T s+++ Ene+v++++L + tr|Q381D3|Q381D3_TRYB2 531 HYLRSELMQALQYANPRCGRVVYATHSLNPLENEAVVASVLTDL 574 568899999999999999**********************9875 PP >> tr|Q38AL4|Q38AL4_TRYB2 Fibrillarin OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb10.6k15.3160 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.6 0.0 2.7e-05 0.019 7 87 .. 136 215 .. 131 225 .. 0.80 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 2.7e-05 -TT-EEEECS-TT-HHHHHHHHHTTTTSEEEEEESSCCCHHHHHHHHHHTT--SEEEEES-CCCCHHHHCC.--EEEEEEEE CS Methyltr_RsmB-F 7 qeeetilDlcaaPGgKTthiaelmknkgtvvAvdankeRlkrvaenlkrLgvtntivleaDarkidkvlgg.elfDriLlDa 87 +++ ++l l aa G +h+++l+ ++g v+Av+ +++ + +++ kr + + Dar++ k+ ++D i +D+ tr|Q38AL4|Q38AL4_TRYB2 136 KPGSKVLYLGAASGTTVSHVSDLVGPEGMVYAVEFSNRSGRDLVDMSKRRPNI--VPIIEDARYPMKYRMLmPMVDCIFMDV 215 66788999***************************999888888888876644..445567887776644336777777775 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (200 nodes) Target sequences: 8561 (4332363 residues searched) Passed MSV filter: 331 (0.0386637); expected 171.2 (0.02) Passed bias filter: 249 (0.0290854); expected 171.2 (0.02) Passed Vit filter: 38 (0.00443873); expected 8.6 (0.001) Passed Fwd filter: 12 (0.00140171); expected 0.1 (1e-05) Initial search space (Z): 8561 [actual number of targets] Domain search space (domZ): 12 [number of targets reported over threshold] # CPU time: 0.11u 0.00s 00:00:00.11 Elapsed: 00:00:00.05 # Mc/sec: 17329.45 // [ok]