# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/Methyltransf_10.hmm.txt
# target sequence database: proteomes/Dictyostelium_discoideum.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: Methyltransf_10 [M=299]
Accession: PF05971.11
Description: Protein of unknown function (DUF890)
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
1.5e-59 201.3 11.5 6.1e-37 127.1 0.6 3.0 3 sp|Q554C9|MET16_DICDI U6 small nuclear RNA (adenine-(43)-N(6
Domain annotation for each sequence (and alignments):
>> sp|Q554C9|MET16_DICDI U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase OS=Dictyostelium discoideum OX=4468
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 127.1 0.6 4.7e-41 6.1e-37 3 189 .. 38 231 .. 36 239 .. 0.86
2 ! 81.4 0.3 4e-27 5e-23 175 299 .] 239 355 .. 234 355 .. 0.85
3 ? -2.4 0.5 0.13 1.7e+03 196 226 .. 515 540 .. 476 562 .. 0.58
Alignments for each domain:
== domain 1 score: 127.1 bits; conditional E-value: 4.7e-41
XXXXXXXXXXXXXXX.XXXXXXXXXXXXXXXXXXXXXXXXXS-TTSHHHHHHHHHHHHHHHH----.---TTS----HHHHHHHHHHH CS
Methyltransf_10 3 lksglhprnrhkdky.dfaalikvvPelkqfvilnpkGrvsidfadPlavkalnkallrefygvsewdiPdgfliPpvPgradyihyv 89
+++++h n ++ ++ +f l++++P + +++i + + + id++d a k l++ ll +++g+++ ++Pd++l+P++ +r++y++++
sp|Q554C9|MET16_DICDI 38 SNDSMHINNFYRYNPpNFKLLASKYPTFDKYIINKTEKIYNIDWKDSNATKELTRVLLDHDFGLRI-ELPDNYLCPTLTLRINYLYWI 124
5789********9988**************************************************.********************* PP
HH......HHT--TCGCS---EEEEES-TTTTHHHHHHHHH.H--EEEEEES-HHHHHHHHHHHHHT.T-TTTEEEEE--ST-SSTTT CS
Methyltransf_10 90 ad......llgkadsdisaqvraldiGvGanCiyPllGvte.yGWrfvgsevddvslasakaivesnsklsdaiklrkqkekkaifdg 170
d ++++++++ ++ ++++diG+G++Ci+PllG+++ + W+f+g ++dd+ l++a++++ n l+++i l k ++++ i+
sp|Q554C9|MET16_DICDI 125 SDqlknlkIILNDNDNDNKIIKGIDIGTGTSCIFPLLGAKLfNNWSFIGIDIDDKVLEYAQNNITIN-SLNSKITLFKNEKNSDILLK 211
*93333222344555566699******************98368***********************.9******9998888888777 PP
STT--S.-EEEEEE-----S CS
Methyltransf_10 171 lieene.rydvtlCnPPfha 189
l + +e ++ n +
sp|Q554C9|MET16_DICDI 212 LLNYKEgSNTFNSSNDDHQD 231
77766646666666655555 PP
== domain 2 score: 81.4 bits; conditional E-value: 4e-27
-S-E..EEEEE-----SS------------...---.....---------TTTTHHHHTHHHHHHHHHHHHHHHGGGEEEEEEEESSG CS
Methyltransf_10 175 nery..dvtlCnPPfhaslaeakagserklknlgkanktralpslnfgGqkaelyceGGevafikklieeskqlakqvlWfttlvskk 260
+e+y d++lCnPPf+ +l+e ++ + + +p++n +G +e++++GGe +f+k++i+es ql+ +++++tt++++k
sp|Q554C9|MET16_DICDI 239 DEEYfaDFCLCNPPFFKDLNENNNNK-------------NNNPKSNCTGSVNEMVTDGGEFEFVKRIIKESFQLKCKIRFYTTMIGRK 313
4444459*********9998753221.............224789******************************************* PP
GGHHHHHHHHHHT...T-SEEEEEEEEETTEEEEEEEEES-- CS
Methyltransf_10 261 enlaplkeelkkl...GaskvtvvelaqGqklsrfiaWsfld 299
nl+pl + l k+ ++++++el+qG++ +++++W fl+
sp|Q554C9|MET16_DICDI 314 VNLNPLINILIKQyylPKNQIQTTELVQGNTSRWVLSWYFLN 355
*******9997752225789*******************987 PP
== domain 3 score: -2.4 bits; conditional E-value: 0.13
-------...---.....---------TTTT CS
Methyltransf_10 196 agserklknlgkanktralpslnfgGqkael 226
+ ++ + + n+++ +++ n+ ++++
sp|Q554C9|MET16_DICDI 515 NNNNNN-----NNNNNNNNNNNNNNNKNNNN 540
111111.....11222222222222222333 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (299 nodes)
Target sequences: 12739 (6856946 residues searched)
Passed MSV filter: 933 (0.0732397); expected 254.8 (0.02)
Passed bias filter: 197 (0.0154643); expected 254.8 (0.02)
Passed Vit filter: 15 (0.00117749); expected 12.7 (0.001)
Passed Fwd filter: 1 (7.84991e-05); expected 0.1 (1e-05)
Initial search space (Z): 12739 [actual number of targets]
Domain search space (domZ): 1 [number of targets reported over threshold]
# CPU time: 0.14u 0.00s 00:00:00.14 Elapsed: 00:00:00.06
# Mc/sec: 34170.45
//
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