# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/Methyltransf_10.hmm.txt # target sequence database: proteomes/Drosophila_melanogaster.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: Methyltransf_10 [M=299] Accession: PF05971.11 Description: Protein of unknown function (DUF890) Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.4e-76 256.6 0.0 2.8e-76 256.3 0.0 1.0 1 sp|Q7K3B9|MET16_DROME U6 small nuclear RNA (adenine-(43)-N( ------ inclusion threshold ------ 0.03 13.3 0.0 0.041 12.9 0.0 1.2 1 tr|Q9VQJ8|Q9VQJ8_DROME Protein-lysine N-methyltransferase CG Domain annotation for each sequence (and alignments): >> sp|Q7K3B9|MET16_DROME U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase OS=Drosophila melanogaster OX=7227 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 256.3 0.0 4.1e-80 2.8e-76 5 298 .. 11 296 .. 7 297 .. 0.94 Alignments for each domain: == domain 1 score: 256.3 bits; conditional E-value: 4.1e-80 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXS-TTSHHHHHHHHHHHHHHHH----.---TTS----HHHHHHHHHHHHHH CS Methyltransf_10 5 sglhprnrhkdkydfaalikvvPelkqfvilnpkGrvsidfadPlavkalnkallrefygvsewdiPdgfliPpvPgradyihyvadl 92 g+hprn + ++d+++++ ++ +++q +l+++G+vs++f++ ++++ l+k ll+e+y++ d g l+P++ +r++yi +++dl sp|Q7K3B9|MET16_DROME 11 VGMHPRNVLRTQPDYTKMAIKYKDFRQQCQLELNGKVSVNFRNEKTLRELTKMLLKEYYDLDV-DFAPGSLVPTLALRLNYILWLEDL 97 58************************************************************9.************************ PP HT--TCGCS---EEEEES-TTTTHHHHHHHHHH--EEEEEES-HHHHHHHHHHHHHT.T-TTTEEEEE--ST-SSTTTSTT--S...- CS Methyltransf_10 93 lgkadsdisaqvraldiGvGanCiyPllGvteyGWrfvgsevddvslasakaivesnsklsdaiklrkqkekkaifdglieene...r 177 + + + ++r++diG G++Ciy llG++++GW+ ++ e ++ +++ak +v+ n +++++i++ q+++++if++ e+++ + sp|Q7K3B9|MET16_DROME 98 MEPLNLQ---NIRGIDIGCGSSCIYSLLGAKKNGWHMLALESKPQNIEYAKENVKRN-HMESLIEVYAQPDNTNIFKSYFEQDQqqlQ 181 9887765...59*********************************************.9********************998876678 PP EEEEEE-----SS--.----------...---.....---------TTTTHHHHTHHHHHHHHHHHHHHHGGGEEEEEEEESSGGGHH CS Methyltransf_10 178 ydvtlCnPPfhasla.eakagserklknlgkanktralpslnfgGqkaelyceGGevafikklieeskqlakqvlWfttlvskkenla 264 y+++lCnPPf++s + + +g+ r++ +++ p+ +G ++el c GGev+f++++i+es + +++v+ ftt+++ k n++ sp|Q7K3B9|MET16_DROME 182 YQFCLCNPPFFDSNLpNPLGGNTRNP--ERRP-----APNNARTGSQEELTCVGGEVQFVQRIIDESLENKERVRIFTTMLGVKANVP 262 ***********987626678899999..3444.....5777899******************************************** PP HHHHHHHHTT-SEEEEEEEEETTEEEEEEEEES- CS Methyltransf_10 265 plkeelkklGaskvtvvelaqGqklsrfiaWsfl 298 + + lk+l + +v ++e+ qG++ ++++aWsf sp|Q7K3B9|MET16_DROME 263 RILDYLKELQVANVSTTEFHQGHTTRWAVAWSFH 296 ********************************96 PP >> tr|Q9VQJ8|Q9VQJ8_DROME Protein-lysine N-methyltransferase CG9643 OS=Drosophila melanogaster OX=7227 GN=Dmel\CG9643 P # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.9 0.0 5.9e-06 0.041 92 181 .. 50 139 .. 43 173 .. 0.74 Alignments for each domain: == domain 1 score: 12.9 bits; conditional E-value: 5.9e-06 HHT--TCGCS---EEEEES-TTTTHHHHHHHHHH--E..EEEEES-HHHHHHHHHHHHHT.T-TTTEEEEE..--ST-SSTTTSTT- CS Methyltransf_10 92 llgkadsdisaqvraldiGvGanCiyPllGvteyGWr..fvgsevddvslasakaivesnsklsdaiklrk..qkekkaifdgliee 174 ll +++ d+ + r+ld+G G l+G + G++ +g + ++++++ a++i e n kls + k+ q++++ +++ tr|Q9VQJ8|Q9VQJ8_DROME 50 LLNEEKIDK-EASRVLDLGCGNGMF--LVGLANEGFTgdLTGVDYSPKAVELAQNIAEDN-KLSITYKVADltQPQNELGQFDVVHD 132 444444444.689********7654..89999999854489*****************99.99998888751145544443445666 PP -S-EEEE CS Methyltransf_10 175 nerydvt 181 + yd++ tr|Q9VQJ8|Q9VQJ8_DROME 133 KGTYDAV 139 6677754 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (299 nodes) Target sequences: 13786 (7394964 residues searched) Passed MSV filter: 407 (0.0295227); expected 275.7 (0.02) Passed bias filter: 289 (0.0209633); expected 275.7 (0.02) Passed Vit filter: 11 (0.000797911); expected 13.8 (0.001) Passed Fwd filter: 2 (0.000145075); expected 0.1 (1e-05) Initial search space (Z): 13786 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.15u 0.01s 00:00:00.16 Elapsed: 00:00:00.05 # Mc/sec: 44221.88 // [ok]