# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/Methyltransf_10.hmm.txt # target sequence database: proteomes/Mus_musculus.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: Methyltransf_10 [M=299] Accession: PF05971.11 Description: Protein of unknown function (DUF890) Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.5e-135 451.6 0.0 1.9e-135 451.3 0.0 1.1 1 sp|Q9CQG2|MET16_MOUSE RNA N6-adenosine-methyltransferase MET Domain annotation for each sequence (and alignments): >> sp|Q9CQG2|MET16_MOUSE RNA N6-adenosine-methyltransferase METTL16 OS=Mus musculus OX=10090 GN=Mettl16 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 451.3 0.0 8.6e-140 1.9e-135 1 299 [] 1 291 [. 1 291 [. 0.99 Alignments for each domain: == domain 1 score: 451.3 bits; conditional E-value: 8.6e-140 XXXXXXXXXXXXXXXXX.XXXXXXXXXXXXXXXXXXXXXXXXXS-TTSHHHHHHHHHHHHHHHH----.---TTS----HHHHHHHHH CS Methyltransf_10 1 aalksglhprnrhkdky.dfaalikvvPelkqfvilnpkGrvsidfadPlavkalnkallrefygvsewdiPdgfliPpvPgradyih 87 +al++++h+rnr+kdk+ dfa+l++++P++kq++++n++Grvs++f+dP+av+al+++llre++g+s+ diP ++liP+vP+r++yih sp|Q9CQG2|MET16_MOUSE 1 MALSKSMHARNRYKDKPpDFAYLASKYPDFKQHIQINLNGRVSLNFKDPEAVRALTCTLLREDFGLSI-DIPLERLIPTVPLRLNYIH 87 6899************99**************************************************.******************* PP HHHHHHT--TCGCS---EEEEES-TTTTHHHHHHHHHH--EEEEEES-HHHHHHHHHHHHHT.T-TTTEEEEE--ST-SSTTTSTT-- CS Methyltransf_10 88 yvadllgkadsdisaqvraldiGvGanCiyPllGvteyGWrfvgsevddvslasakaivesnsklsdaiklrkqkekkaifdglieen 175 +v+dl+g++dsd+++ +r++diG+Ga+CiyPllG+t++GW+f+++evdd+++++ak++ve+n +lsd+ik++k+++k+ ++d+l+ee+ sp|Q9CQG2|MET16_MOUSE 88 WVEDLIGHQDSDKTTLRRGIDIGTGASCIYPLLGATLNGWYFLATEVDDMCFNYAKKNVEQN-NLSDLIKVVKVPQKTLLMDALKEES 174 **************************************************************.************************* PP S.-EEEEEE-----SS------------...---.....---------TTTTHHHHTHHHHHHHHHHHHHHHGGGEEEEEEEESSGGG CS Methyltransf_10 176 e.rydvtlCnPPfhaslaeakagserklknlgkanktralpslnfgGqkaelyceGGevafikklieeskqlakqvlWfttlvskken 262 e yd+++CnPPf+a+++eak++++r+ +++ +ps++++G+++e+++eGGe++f+k++i++s ql+k+++W++++++kk++ sp|Q9CQG2|MET16_MOUSE 175 EiVYDFCMCNPPFFANQLEAKGVNSRNS---RRP-----PPSSVNTGGITEIMAEGGELEFVKRIIHDSLQLKKRLRWYSCMLGKKCS 254 *99***********************99...776.....899********************************************** PP HHHHHHHHHHTT-SEEEEEEEEETTEEEEEEEEES-- CS Methyltransf_10 263 laplkeelkklGaskvtvvelaqGqklsrfiaWsfld 299 laplkeel+++G++kvt +e++qG+++++++aWsf+d sp|Q9CQG2|MET16_MOUSE 255 LAPLKEELRIQGVPKVTFTEFCQGRTMRWALAWSFYD 291 ***********************************97 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (299 nodes) Target sequences: 22289 (11757923 residues searched) Passed MSV filter: 489 (0.0219391); expected 445.8 (0.02) Passed bias filter: 386 (0.017318); expected 445.8 (0.02) Passed Vit filter: 26 (0.00116649); expected 22.3 (0.001) Passed Fwd filter: 1 (4.48652e-05); expected 0.2 (1e-05) Initial search space (Z): 22289 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.24u 0.01s 00:00:00.25 Elapsed: 00:00:00.08 # Mc/sec: 43945.24 // [ok]