# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/Methyltransf_10.hmm.txt # target sequence database: proteomes/Strongylocentrotus_purpuratus.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: Methyltransf_10 [M=299] Accession: PF05971.11 Description: Protein of unknown function (DUF890) Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2e-89 300.5 0.0 2.8e-89 300.1 0.0 1.2 1 tr|W4YFA7|W4YFA7_STRPU Uncharacterized protein OS=Strongyloc ------ inclusion threshold ------ 1.7 8.5 28.5 8.2 6.3 1.4 6.7 7 tr|W4Y6M0|W4Y6M0_STRPU Uncharacterized protein OS=Strongyloc Domain annotation for each sequence (and alignments): >> tr|W4YFA7|W4YFA7_STRPU Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 300.1 0.0 2e-93 2.8e-89 2 298 .. 2 292 .. 1 293 [. 0.94 Alignments for each domain: == domain 1 score: 300.1 bits; conditional E-value: 2e-93 XXXXXXXXXXXXXXXX.XXXXXXXXXXXXXXXXXXXXXXXXXS-TTSHHHHHHHHHHHHHHHH----.---TTS----HHHHHHHHH CS Methyltransf_10 2 alksglhprnrhkdky.dfaalikvvPelkqfvilnpkGrvsidfadPlavkalnkallrefygvsewdiPdgfliPpvPgradyih 87 a ++ +hprnr+kd+ +f +l++++Pe+ ++vi n +G+ ++df d ++++ l+++ll+e++g++ ++P ++liP++ +r++yih tr|W4YFA7|W4YFA7_STRPU 2 AFNKFMHPRNRYKDNKpNFDELAEKYPEFARHVIRNQAGKATLDFHDSESLRSLTCTLLKEDFGLEV-ELPLDRLIPTLSLRLNYIH 87 67889********8655************************************************99.******************* PP HHHHHHT--TCGCS---EEEEES-TTTTHHHHHHHHHH--EEEEEES-HHHHHHHHHHHHHT.T-TTTEEEEE--ST-SSTTTSTT- CS Methyltransf_10 88 yvadllgkadsdisaqvraldiGvGanCiyPllGvteyGWrfvgsevddvslasakaivesnsklsdaiklrkqkekkaifdgliee 174 +++dll+++ +++ ++v ++d G Ga+CiyPllG++ +GW+f++sevd ++ +ak ++ n l+d+i ++ e ++ ++l + tr|W4YFA7|W4YFA7_STRPU 88 WIEDLLASTGHGK-ETVWGIDTGCGASCIYPLLGAQMNGWNFLASEVDALAIYYAKENITRN-GLDDKITVVETLEDSMFEQALNSA 172 *******999888.7899********************************************.**********99999888888876 PP -S...-EEEEEE-----SS------------...---.....---------TTTTHHHHTHHHHHHHHHHHHHHHGGGEEEEEEEES CS Methyltransf_10 175 ne...rydvtlCnPPfhaslaeakagserklknlgkanktralpslnfgGqkaelyceGGevafikklieeskqlakqvlWfttlvs 258 y +t+CnPPf+ + +ea++ + + ++ +p+++ + + e+++eGGev+f++++iees l++qv+W+t++++ tr|W4YFA7|W4YFA7_STRPU 173 PSrqpLYHFTMCNPPFFGNSLEAQGIMTSRS--MSRP-----EPKSVSTAAELEMISEGGEVEFVRRMIEESLRLRNQVVWYTSMLG 252 542237******************9865544..5666.....79999**************************************** PP SGGGHHHHHHHHHHTT-SEEEEEEEEETTEEEEEEEEES- CS Methyltransf_10 259 kkenlaplkeelkklGaskvtvvelaqGqklsrfiaWsfl 298 kk++la ++eel+k + +vt +e++qG+++++ iaW+f tr|W4YFA7|W4YFA7_STRPU 253 KKSSLALVREELRKHKIRNVTHTEFCQGRTMRWGIAWTFK 292 ***************************************7 PP >> tr|W4Y6M0|W4Y6M0_STRPU Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.2 0.3 0.0026 37 161 202 .. 12 56 .. 4 69 .. 0.73 2 ? 4.1 0.2 0.0027 38 184 218 .. 71 106 .. 68 114 .. 0.71 3 ? 3.1 0.1 0.0056 80 184 203 .. 104 123 .. 99 136 .. 0.76 4 ? 3.1 2.1 0.0053 76 182 212 .. 135 166 .. 111 199 .. 0.67 5 ? 6.3 1.4 0.00058 8.2 160 225 .. 197 266 .. 174 270 .. 0.71 6 ? 4.2 0.5 0.0026 37 184 225 .. 257 299 .. 252 313 .. 0.76 7 ? 1.0 0.3 0.024 3.4e+02 166 205 .. 302 344 .. 295 367 .. 0.65 Alignments for each domain: == domain 1 score: 4.2 bits; conditional E-value: 0.0026 --ST-SSTTTSTT--S.-EEEE..EE-----SS------------ CS Methyltransf_10 161 qkekkaifdglieene.rydvt..lCnPPfhaslaeakagserkl 202 q+e ++i + +e++e r + PPf +s++ea++ ++r + tr|W4Y6M0|W4Y6M0_STRPU 12 QEEANKIQQRAKERSEgRVNSKtpQGSPPFTDSQEEANEIQQRAK 56 556667777777777765443301568*************99976 PP == domain 2 score: 4.1 bits; conditional E-value: 0.0027 -----SS----------.--...---.....----- CS Methyltransf_10 184 nPPfhaslaeakagser.klknlgkanktralpsln 218 PPf +s++ea++ ++r k + g++n ++ + s tr|W4Y6M0|W4Y6M0_STRPU 71 SPPFTDSQEEANEIQQRaKERSEGRVNSKTPQGSPP 106 6*************9993445667776655555555 PP == domain 3 score: 3.1 bits; conditional E-value: 0.0056 -----SS------------. CS Methyltransf_10 184 nPPfhaslaeakagserklk 203 PPf +s++ea++ ++r ++ tr|W4Y6M0|W4Y6M0_STRPU 104 SPPFTDSQEEANEIQQRAKE 123 6*************999653 PP == domain 4 score: 3.1 bits; conditional E-value: 0.0053 EE-----SS------------....---.... CS Methyltransf_10 182 lCnPPfhaslaeakagserkl.knlgkanktr 212 PPf +s++ea + ++r + + g++n ++ tr|W4Y6M0|W4Y6M0_STRPU 135 QGSPPFTDSQEEADNIQQRAKeRSEGRVNSKT 166 457************99995515556665533 PP == domain 5 score: 6.3 bits; conditional E-value: 0.00058 E--ST-SSTTTSTT--S.-EEEE..EE-----SS----------.--...---.....---------TTT CS Methyltransf_10 160 kqkekkaifdglieene.rydvt..lCnPPfhaslaeakagser.klknlgkanktralpslnfgGqkae 225 q+e ++i + +e++e r + PPf +s++ea++ ++r k + g++n ++ + s f+ ++e tr|W4Y6M0|W4Y6M0_STRPU 197 SQEEANNIQQRAKERSEgRVNSKtpQGSPPFTDSQEEANNIQQRaKERSEGRVNSKTPQGSPPFTDSQEE 266 5667777777778888775544311568*************99944567788877777677777766666 PP == domain 6 score: 4.2 bits; conditional E-value: 0.0026 -----SS----------.--...---.....---------TTT CS Methyltransf_10 184 nPPfhaslaeakagser.klknlgkanktralpslnfgGqkae 225 PPf +s++ea + ++r k + g++n ++ + s f+ ++e tr|W4Y6M0|W4Y6M0_STRPU 257 SPPFTDSQEEAYNIQQRaKERSEGRVNSKTPQGSPSFTDSQEE 299 69**********9999944567788887666666666655554 PP == domain 7 score: 1.0 bits; conditional E-value: 0.024 SSTTTSTT--S.-EE..EEEE-----SS------------... CS Methyltransf_10 166 aifdglieene.ryd..vtlCnPPfhaslaeakagserklknl 205 +i + +e++e r + PPf +s++e + ++r +k tr|W4Y6M0|W4Y6M0_STRPU 302 NIQQRAKERSEgRVNskTPQGSPPFTDSQEEPDNIQQRAPKTS 344 5555556666654431033467**************9998653 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (299 nodes) Target sequences: 28594 (14266044 residues searched) Passed MSV filter: 611 (0.0213681); expected 571.9 (0.02) Passed bias filter: 492 (0.0172064); expected 571.9 (0.02) Passed Vit filter: 44 (0.00153878); expected 28.6 (0.001) Passed Fwd filter: 2 (6.99447e-05); expected 0.3 (1e-05) Initial search space (Z): 28594 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.30u 0.01s 00:00:00.31 Elapsed: 00:00:00.10 # Mc/sec: 42655.47 // [ok]