# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/Methyltransf_10.hmm.txt
# target sequence database: proteomes/Tetrahymena_thermophila.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: Methyltransf_10 [M=299]
Accession: PF05971.11
Description: Protein of unknown function (DUF890)
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
1.9e-64 218.4 9.6 1.4e-62 212.3 4.5 3.2 2 tr|Q231G1|Q231G1_TETTS U6 small nuclear RNA (adenine-(43)-N(
2.9e-05 24.1 0.0 4e-05 23.7 0.0 1.1 1 tr|W7XCF3|W7XCF3_TETTS HemK methyltransferase family protein
------ inclusion threshold ------
0.05 13.5 0.0 0.081 12.8 0.0 1.3 1 tr|I7MAE9|I7MAE9_TETTS UbiE/COQ5 family methyltransferase OS
Domain annotation for each sequence (and alignments):
>> tr|Q231G1|Q231G1_TETTS U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase OS=Tetrahymena thermophila (strain
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 212.3 4.5 1.6e-66 1.4e-62 14 278 .. 71 317 .. 58 322 .. 0.91
2 ? 2.7 0.2 0.011 1e+02 271 297 .. 424 450 .. 343 451 .] 0.78
Alignments for each domain:
== domain 1 score: 212.3 bits; conditional E-value: 1.6e-66
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXS-TTSHHHHHHHHHHHHHHHH----.---TTS----HHHHHHHHHHHHHHHT..--TC CS
Methyltransf_10 14 kdkydfaalikvvPelkqfvilnpkGrvsidfadPlavkalnkallrefygvsewdiPdgfliPpvPgradyihyvadllg..kads 98
k + df +l+ +P l+ +v +n +Gr++id+ + +a k ln+a+l+ ++++ +wd+P++ liP++P r++y+ ++ + l k ++
tr|Q231G1|Q231G1_TETTS 71 KFQWDFDELAIHYPPLNDYVFINERGRTTIDWTNTAAHKTLNQAILAVQFKIVYWDMPQDQLIPTIPSRLNYLEWIHNKLQslKINN 157
4467*************************************************************************9996225678 PP
GCS---EEEEES-TTTTHHHHHHHHHH--EEEEEES-HHHHHHHHHHHHHT.T-TTTEEEEE--ST-SSTTTSTT--S.-EEEEEE- CS
Methyltransf_10 99 disaqvraldiGvGanCiyPllGvteyGWrfvgsevddvslasakaivesnsklsdaiklrkqkekkaifdglieene.rydvtlCn 184
+ s+q++a+diG+Ga+ iyP+lG+ +y W+f+++e++d s ++ak+i+++n++l+++++lrk + +if+ +i++++ +t+Cn
tr|Q231G1|Q231G1_TETTS 158 EQSNQIKAIDIGTGASVIYPILGASKYNWSFIATELSDASYQNAKKIINNNPQLKNKVELRKS--QGNIFKDIIQKSDgDISFTMCN 242
8999*******************************************************9975..689*******99989******* PP
----SS------------...---.....---------TTTTHHHHTHHHHHHHHHHHHHHHGGGEEEEEEEESSGGGHHHHHHHHH CS
Methyltransf_10 185 PPfhaslaeakagserklknlgkanktralpslnfgGqkaelyceGGevafikklieeskqlakqvlWfttlvskkenlaplkeelk 271
PPf+++ +e + + n +++e +ceGGe++f+k++ eesk +a+q+ ft+lv+k++n++++ + lk
tr|Q231G1|Q231G1_TETTS 243 PPFFSEHEEKQI-----WVN--------------AQMKENEYICEGGELQFLKQMFEESKIFANQIKIFTSLVGKQTNFEQFLQYLK 310
****98776443.....322..............23356899********************************************* PP
HTT-SEE CS
Methyltransf_10 272 klGaskv 278
++ ++++
tr|Q231G1|Q231G1_TETTS 311 QQNIQNL 317
9998876 PP
== domain 2 score: 2.7 bits; conditional E-value: 0.011
HHTT-SEEEEEEEEETTEEEEEEEEES CS
Methyltransf_10 271 kklGaskvtvvelaqGqklsrfiaWsf 297
+k+ +++ ++qG++ ++++ W f
tr|Q231G1|Q231G1_TETTS 424 NKQVSVQIFEGSIVQGNTTRWIVGWRF 450
3455567888889************98 PP
>> tr|W7XCF3|W7XCF3_TETTS HemK methyltransferase family protein OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 23.7 0.0 4.4e-09 4e-05 56 193 .. 68 208 .. 59 235 .. 0.78
Alignments for each domain:
== domain 1 score: 23.7 bits; conditional E-value: 4.4e-09
HHHHHHHH----.---TTS-..---HHHHHHHHHHHHHHHT--TCGCS---EEEEES-TTTTHHHHHHHHHH--EEEEEES-HHHHH CS
Methyltransf_10 56 kallrefygvsewdiPdgfl..iPpvPgradyihyvadllgkadsdisaqvraldiGvGanCiyPllGvteyGWrfvgsevddvsla 140
+a++ +y + ew+ d l Ppv + y+ +l+ k ++++ ++ + l+iG+G+ i l +++ ++ ++ + ++ +++
tr|W7XCF3|W7XCF3_TETTS 68 RAMMPIQYVIGEWEFRDLLLkmKPPVLIPRNETSYLVELVNKLSKQK-QKCQFLEIGIGTGAISLSLLKENSQFTGIAIDKQKFCIE 153
6788889999999999876633699999999999*******999998.7788899998888887656555555666666666779** PP
HHHHHHHHT.T-TTTEEEEE--ST-SSTTTSTT--S.-EEEEEE-----S.S--- CS
Methyltransf_10 141 sakaivesnsklsdaiklrkqkekkaifdglieene.rydvtlCnPPfha.slae 193
ak++++ n + ++l + + k + l ++ + ++d+ + nPP+ s+ +
tr|W7XCF3|W7XCF3_TETTS 154 LAKQNLNLNKIDPQRLQLIHLECLKFFQNNLNQNPDqQFDFIVSNPPYIPtSQVQ 208
*********6666889999888888888888877555**********97414444 PP
>> tr|I7MAE9|I7MAE9_TETTS UbiE/COQ5 family methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTH
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 12.8 0.0 9e-06 0.081 97 154 .. 46 104 .. 31 130 .. 0.77
Alignments for each domain:
== domain 1 score: 12.8 bits; conditional E-value: 9e-06
TCGCS---EEEEES-TT.TTHHHHHHHHHH--EEEEEES-HHHHHHHHHHHHHT.T-TT CS
Methyltransf_10 97 dsdisaqvraldiGvGa.nCiyPllGvteyGWrfvgsevddvslasakaivesnsklsd 154
+++ + +r+ld+GvG+ +y ++ + +g ++d + ak+i ++ s+++
tr|I7MAE9|I7MAE9_TETTS 46 KGNEKNFKRILDVGVGTgHPLYSIIDRIPKSVQVTGIDIDTNYIPAAKKIFSKHSNVEI 104
44455679********8357*******************************99887653 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (299 nodes)
Target sequences: 26971 (16912921 residues searched)
Passed MSV filter: 1867 (0.0692225); expected 539.4 (0.02)
Passed bias filter: 292 (0.0108264); expected 539.4 (0.02)
Passed Vit filter: 23 (0.000852768); expected 27.0 (0.001)
Passed Fwd filter: 3 (0.000111231); expected 0.3 (1e-05)
Initial search space (Z): 26971 [actual number of targets]
Domain search space (domZ): 3 [number of targets reported over threshold]
# CPU time: 0.31u 0.01s 00:00:00.32 Elapsed: 00:00:00.11
# Mc/sec: 45972.39
//
[ok]