# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/Methyltransf_11.hmm.txt # target sequence database: proteomes/Natronomonas_moolapensis.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: Methyltransf_11 [M=95] Accession: PF08241.11 Description: Methyltransferase domain Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.4e-25 85.5 0.0 1.6e-24 83.8 0.0 1.8 2 tr|M1XNA3|M1XNA3_NATM8 Probable demethylmenaquinone methyltr 7e-24 81.7 1.4 1.2e-23 81.0 0.0 2.1 1 tr|M1XL08|M1XL08_NATM8 Probable arsenite(III)-methyltransfer 1.3e-23 80.8 0.0 2.1e-23 80.1 0.0 1.3 1 tr|M1Y4D2|M1Y4D2_NATM8 Probable S-adenosylmethionine-depende 3e-23 79.7 0.0 4.5e-23 79.1 0.0 1.3 1 tr|M1XP07|M1XP07_NATM8 Probable S-adenosylmethionine-depende 7.9e-20 68.7 0.0 2.8e-19 66.9 0.1 1.8 2 tr|M1XQI1|M1XQI1_NATM8 Probable S-adenosylmethionine-depende 4.5e-19 66.3 0.2 6.4e-19 65.8 0.2 1.2 1 tr|M1XNP7|M1XNP7_NATM8 Probable S-adenosylmethionine-depende 1.3e-18 64.8 0.0 1.9e-18 64.3 0.0 1.3 1 tr|M1XKD3|M1XKD3_NATM8 Probable S-adenosylmethionine-depende 1.2e-16 58.4 0.1 3.1e-16 57.2 0.1 1.7 1 tr|M1XTN7|M1XTN7_NATM8 Probable S-adenosylmethionine-depende 1.5e-16 58.2 0.0 2.2e-16 57.7 0.0 1.3 1 tr|M1Y1P2|M1Y1P2_NATM8 Probable S-adenosylmethionine-depende 2.4e-14 51.1 0.0 4.4e-14 50.3 0.0 1.4 1 tr|M1XQ74|M1XQ74_NATM8 Probable S-adenosylmethionine-depende 9.7e-13 45.9 0.0 1.6e-12 45.3 0.0 1.3 1 tr|M1XL59|M1XL59_NATM8 Probable S-adenosylmethionine-depende 1.2e-12 45.6 0.0 2.1e-12 44.8 0.0 1.4 1 tr|M1XLC7|M1XLC7_NATM8 Probable S-adenosylmethionine-depende 2.8e-12 44.5 0.0 4.8e-12 43.7 0.0 1.4 1 tr|M1XLH6|M1XLH6_NATM8 Homolog to S-adenosylmethionine-depen 3.9e-10 37.6 0.0 8.6e-10 36.5 0.0 1.5 1 tr|M1XS10|M1XS10_NATM8 Probable rRNA methyltransferase OS=Na 1e-08 33.1 0.1 2.8e-07 28.4 0.0 2.2 2 tr|M1XRL7|M1XRL7_NATM8 Probable S-adenosylmethionine-depende 4.3e-07 27.8 0.2 1e-06 26.7 0.2 1.6 1 tr|M1XTL7|M1XTL7_NATM8 tRNA (Adenine-N(1))-methyltransferase 4.8e-07 27.7 0.2 1.5e-06 26.1 0.1 1.9 2 tr|M1XLF5|M1XLF5_NATM8 tRNA (Guanine(10),N(2))-dimethyltrans 2.4e-05 22.3 0.0 4.6e-05 21.3 0.0 1.6 2 tr|M1Y5Q2|M1Y5Q2_NATM8 Probable cobalt-precorrin-6B C(15)-me 0.00017 19.6 0.0 0.00041 18.3 0.0 1.7 1 tr|M1Y3X8|M1Y3X8_NATM8 tRNA (Guanine(37)-N(1))-methyltransfe 0.00058 17.8 0.0 0.0019 16.2 0.0 1.9 2 tr|M1Y1T3|M1Y1T3_NATM8 Probable S-adenosylmethionine-depende 0.0016 16.4 0.1 0.005 14.8 0.1 1.9 1 tr|M1XZU1|M1XZU1_NATM8 Protein-L-isoaspartate O-methyltransf 0.002 16.1 0.0 0.41 8.7 0.0 2.7 2 tr|M1XKR6|M1XKR6_NATM8 Modification methylase OS=Natronomona 0.0046 15.0 0.1 0.014 13.4 0.1 1.9 1 tr|M1Y5X6|M1Y5X6_NATM8 Pyrroline-5-carboxylate reductase OS= 0.0071 14.3 0.0 0.011 13.7 0.0 1.4 1 tr|M1XP14|M1XP14_NATM8 Protein-L-isoaspartate O-methyltransf 0.0082 14.1 0.1 0.18 9.9 0.1 2.7 2 tr|M1XK62|M1XK62_NATM8 tRNA (guanine(26)-N(2))-dimethyltrans 0.0089 14.0 0.1 0.055 11.5 0.0 2.4 2 tr|M1XN99|M1XN99_NATM8 tRNA(Phe) (4-demethylwyosine(37)-C(7) ------ inclusion threshold ------ 0.017 13.1 0.0 0.034 12.1 0.0 1.5 1 tr|M1XRN3|M1XRN3_NATM8 Probable ribosomal RNA small subunit Domain annotation for each sequence (and alignments): >> tr|M1XNA3|M1XNA3_NATM8 Probable demethylmenaquinone methyltransferase OS=Natronomonas moolapensis (strain DSM 18674 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 83.8 0.0 1.5e-26 1.6e-24 1 93 [. 50 142 .. 50 144 .. 0.95 2 ? -1.0 0.0 4.3 4.3e+02 48 86 .. 158 204 .. 150 210 .. 0.61 Alignments for each domain: == domain 1 score: 83.8 bits; conditional E-value: 1.5e-26 EEET-TTSHHHHHHHHTTSEEEEEES-HHHHHHHHHHCCHHT-EEETTEECCCTSS-TT-EEEEEEES-CCC-CCHHHHHHHHHHHE CS Methyltransf_11 1 LdvGcGtGrlaealakrgarvvgvDlspemlklakekaseeglvefvvadaeklpfpdnsfDlvvssevlhhvedpekalkeiaRvL 87 LdvGcGtG +e l ++ +v g+D s+++l+ a k +++ v+f+++dae+lpf+d+sfD+ +ss ++++++dp +al+e++Rv tr|M1XNA3|M1XNA3_NATM8 50 LDVGCGTGFATEGLLEHTDDVWGLDQSAHQLEKAFGKFGKRDRVNFHRGDAERLPFADDSFDAYWSSGSIEYWPDPVAALREARRVT 136 8******************************999888877777******************************************** PP EEEEEE CS Methyltransf_11 88 kpgGll 93 kpgG + tr|M1XNA3|M1XNA3_NATM8 137 KPGGPV 142 ****76 PP == domain 2 score: -1.0 bits; conditional E-value: 4.3 TEECCCTSS-TT-EEEEEEES-CCC-........CCHHHHHHHHHHH CS Methyltransf_11 48 vadaeklpfpdnsfDlvvssevlhhv........edpekalkeiaRv 86 ada l + ++ D ++ + ++ + + +a+ iaRv tr|M1XNA3|M1XNA3_NATM8 158 LADAIMLFYDEAEADRMFAEAGFQAFehriqqraPGTPRAITTIARV 204 56777777777888888888877766322322222445555555555 PP >> tr|M1XL08|M1XL08_NATM8 Probable arsenite(III)-methyltransferase OS=Natronomonas moolapensis (strain DSM 18674 / JCM # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 81.0 0.0 1.2e-25 1.2e-23 1 95 [] 100 199 .. 100 199 .. 0.96 Alignments for each domain: == domain 1 score: 81.0 bits; conditional E-value: 1.2e-25 EEET-TTSHHHHHHHHTT...SEEEEEES-HHHHHHHHHHCCHHT-..EEETTEECCCTSS-TT-EEEEEEES-CCC-CCHHHHHHH CS Methyltransf_11 1 LdvGcGtGrlaealakrg...arvvgvDlspemlklakekaseegl..vefvvadaeklpfpdnsfDlvvssevlhhvedpekalke 82 Ld+G+G+G + a+ + +rv+gvD++pem+k a+++as++g vef+ +++e+lp+ d+s+D+++s+ v++ +d ++++e tr|M1XL08|M1XL08_NATM8 100 LDLGSGAGFDCFLAAQEVgetGRVIGVDMTPEMIKKARANASQNGAenVEFRLGEIEHLPVSDDSIDVIISNCVVNLSPDKPQVFDE 186 8************995556999**********************99***************************************** PP HHHHEEEEEEEEE CS Methyltransf_11 83 iaRvLkpgGllvi 95 + RvL+pgG+l+i tr|M1XL08|M1XL08_NATM8 187 AFRVLRPGGRLAI 199 **********986 PP >> tr|M1Y4D2|M1Y4D2_NATM8 Probable S-adenosylmethionine-dependent methyltransferase OS=Natronomonas moolapensis (strain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 80.1 0.0 2.1e-25 2.1e-23 1 87 [. 49 138 .. 49 143 .. 0.97 Alignments for each domain: == domain 1 score: 80.1 bits; conditional E-value: 2.1e-25 EEET-TTSHHHHHHHHTTSEEEEEES-HHHHHHHHHHCCHHT-...EEETTEECCCTSS-TT-EEEEEEES-CCC-CCHHHHHHHHH CS Methyltransf_11 1 LdvGcGtGrlaealakrgarvvgvDlspemlklakekaseegl...vefvvadaeklpfpdnsfDlvvssevlhhvedpekalkeia 84 L+v+cGtGr++ la+rga++vg+D+s++ml++ ++ka+ +g+ ++f+++da +lpfpd+ fD+v++ ++h +dpe +++e++ tr|M1Y4D2|M1Y4D2_NATM8 49 LEVACGTGRFTVMLADRGADIVGMDISEAMLEQGRRKARSAGVdesLSFIQGDAGRLPFPDDHFDAVLAMRFFHLAPDPEGFIAEMR 135 89********************************9999999999999**************************************** PP HHE CS Methyltransf_11 85 RvL 87 Rv tr|M1Y4D2|M1Y4D2_NATM8 136 RVA 138 *96 PP >> tr|M1XP07|M1XP07_NATM8 Probable S-adenosylmethionine-dependent methyltransferase (Homolog to 24-sterol C-methyltrans # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 79.1 0.0 4.5e-25 4.5e-23 1 95 [] 43 138 .. 43 138 .. 0.96 Alignments for each domain: == domain 1 score: 79.1 bits; conditional E-value: 4.5e-25 EEET-TTSHHHHHHHHTT..SEEEEEES-HHHHHHHHHHCCHHT-EEETTEECCCTSS-TT-EEEEEEES-CCC-CCHHHHHHHHHH CS Methyltransf_11 1 LdvGcGtGrlaealakrg..arvvgvDlspemlklakekaseeglvefvvadaeklpfpdnsfDlvvssevlhhvedpekalkeiaR 85 Ld+GcG+G+ +al + arv+g+D +pem++ a++ + ++ v +v +d+ +lpf d+s+D +s e++ + +dp+++l e++R tr|M1XP07|M1XP07_NATM8 43 LDLGCGSGYAGRALREATdaARVYGLDGAPEMVRNARSYTDDPA-VGYVLGDFDSLPFVDDSVDHAFSMEAFYYAPDPHSTLCELRR 128 8**************77778****************99999998.9***************************************** PP HEEEEEEEEE CS Methyltransf_11 86 vLkpgGllvi 95 vL+pgG++++ tr|M1XP07|M1XP07_NATM8 129 VLRPGGTFYC 138 *******986 PP >> tr|M1XQI1|M1XQI1_NATM8 Probable S-adenosylmethionine-dependent methyltransferase OS=Natronomonas moolapensis (strain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 66.9 0.1 2.8e-21 2.8e-19 1 95 [] 42 126 .. 42 126 .. 0.95 2 ? -1.1 0.0 4.7 4.7e+02 14 42 .. 138 166 .. 131 179 .. 0.70 Alignments for each domain: == domain 1 score: 66.9 bits; conditional E-value: 2.8e-21 EEET-TTSHHHHHHHHTTSEEEEEES-HHHHHHHHHHCCHHT-EEETTEECCCTSS-TT-EEEEEEES-CCC-CCHHHHHHHHHHHE CS Methyltransf_11 1 LdvGcGtGrlaealakrgarvvgvDlspemlklakekaseeglvefvvadaeklpfpdnsfDlvvssevlhhvedpekalkeiaRvL 87 LdvG G+Gr+a + + vD++ ml++a++++ e+ v+a+a++lp pd+s+D+vv+ ++hh++ +++l+e+aRvL tr|M1XQI1|M1XQI1_NATM8 42 LDVGGGSGRVAGETG-----ATVVDPARGMLRRARRRGLES-----VQASATDLPHPDGSVDAVVVVDAFHHFPAGQRCLSEMARVL 118 8**********9999.....788********9999888776.....9**************************************** PP EEEEEEEE CS Methyltransf_11 88 kpgGllvi 95 pgG+lvi tr|M1XQI1|M1XQI1_NATM8 119 APGGVLVI 126 *****996 PP == domain 2 score: -1.1 bits; conditional E-value: 4.7 HHHTTSEEEEEES-HHHHHHHHHHCCHHT CS Methyltransf_11 14 lakrgarvvgvDlspemlklakekaseeg 42 +r++r+vg+D + +++ ++++ +g tr|M1XQI1|M1XQI1_NATM8 138 ALDRAERLVGFDSTFYTVSELESAIGSAG 166 44667899999988888877777766665 PP >> tr|M1XNP7|M1XNP7_NATM8 Probable S-adenosylmethionine-dependent methyltransferase OS=Natronomonas moolapensis (strain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 65.8 0.2 6.4e-21 6.4e-19 1 94 [. 42 135 .. 42 136 .. 0.95 Alignments for each domain: == domain 1 score: 65.8 bits; conditional E-value: 6.4e-21 EEET-TTSHHHHHHHHTTSEEEEEES-HHHHHHHHHHCCHHT-EEETTEECCCTSS-TT-EEEEEEES-CCC-...CCHHHHHHHHH CS Methyltransf_11 1 LdvGcGtGrlaealakrgarvvgvDlspemlklakekaseeglvefvvadaeklpfpdnsfDlvvssevlhhv...edpekalkeia 84 LdvGcG+Gr++e la ++ rv+g+D+s+ +l +a+e+a+++ +v +da +lp++d+ + l v ++lhh+ +++ l+e+a tr|M1XNP7|M1XNP7_NATM8 42 LDVGCGNGRHTELLAGHADRVLGLDVSHGLLSAARERAPGAA---LVAGDAASLPVADGAVGLAVYVATLHHLptrRLRRESLDELA 125 8**************999**********************98...49**************************8877999******* PP HHEEEEEEEE CS Methyltransf_11 85 RvLkpgGllv 94 RvL gG+ + tr|M1XNP7|M1XNP7_NATM8 126 RVLDDGGVAL 135 *******976 PP >> tr|M1XKD3|M1XKD3_NATM8 Probable S-adenosylmethionine-dependent methyltransferase OS=Natronomonas moolapensis (strain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 64.3 0.0 1.9e-20 1.9e-18 1 94 [. 45 135 .. 45 136 .. 0.92 Alignments for each domain: == domain 1 score: 64.3 bits; conditional E-value: 1.9e-20 EEET-TTSHHHHHHHHTTSEEEEEES-HHHHHHHHHHCCHHT-EEETTEECCCTSS-TT-EEEEEEES-CCC-..CCHHHHHHHHHH CS Methyltransf_11 1 LdvGcGtGrlaealakrgarvvgvDlspemlklakekaseeglvefvvadaeklpfpdnsfDlvvssevlhhv..edpekalkeiaR 85 LdvGcG G+ + a g vgvD+s + l+la e ++ ++ +v++++++lpf+d+ fD+++++++++hv ++ ++ +e+aR tr|M1XKD3|M1XKD3_NATM8 45 LDVGCGDGARTLANLPPG--SVGVDISRRGLDLAAETTPVAR---LVHGEMSELPFADGVFDAITAYHAVFHVprGRHPEVYAEFAR 126 8*****999998888777..9*************88888876...5***************************77799********* PP HEEEEEEEE CS Methyltransf_11 86 vLkpgGllv 94 vL+pgG+l+ tr|M1XKD3|M1XKD3_NATM8 127 VLRPGGRLL 135 *******97 PP >> tr|M1XTN7|M1XTN7_NATM8 Probable S-adenosylmethionine-dependent methyltransferase OS=Natronomonas moolapensis (strain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.2 0.1 3.1e-18 3.1e-16 1 87 [. 36 115 .. 36 122 .. 0.91 Alignments for each domain: == domain 1 score: 57.2 bits; conditional E-value: 3.1e-18 EEET-TTSHHHHHHHHTT.SEEEEEES-HHHHHHHHHHCCHHT-EEETTEECCCTSS-TT-EEEEEEES-CCC-CCHHHHHHHHHHH CS Methyltransf_11 1 LdvGcGtGrlaealakrg.arvvgvDlspemlklakekaseeglvefvvadaeklpfpdnsfDlvvssevlhhvedpekalkeiaRv 86 +dvGcG G+l++ l + + ++vvg+D ++++l a+ +++ v++da +lpf+d+s+Dlv +++ l +++dp +a++e+aRv tr|M1XTN7|M1XTN7_NATM8 36 VDVGCGEGALTRVLREECpGEVVGCDRDARLL--AEL--EGPT----VRGDAYRLPFADGSVDLVACQALLINLPDPGRAVREFARV 114 69*****************************9..433..4443....99*************************************9 PP E CS Methyltransf_11 87 L 87 tr|M1XTN7|M1XTN7_NATM8 115 A 115 6 PP >> tr|M1Y1P2|M1Y1P2_NATM8 Probable S-adenosylmethionine-dependent methyltransferase OS=Natronomonas moolapensis (strain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.7 0.0 2.1e-18 2.2e-16 2 95 .] 42 133 .. 41 133 .. 0.94 Alignments for each domain: == domain 1 score: 57.7 bits; conditional E-value: 2.1e-18 EET-TTSHHHHHHHHTTSEEEEEES-HHHHHHHHHHCCHHT-EEETTEECCCTSS-TT-EEEEEEES-CCC-CCHHHHHHHHHHHEE CS Methyltransf_11 2 dvGcGtGrlaealakrgarvvgvDlspemlklakekaseeglvefvvadaeklpfpdnsfDlvvssevlhhvedpekalkeiaRvLk 88 d+G+GtG ++ +a+++++v +vD+ ++m+++ ek+ +++ v+ v a + lpf+d+ D+ + +++ h + +a+ eiaRvL tr|M1Y1P2|M1Y1P2_NATM8 42 DLGSGTGFYTDLVARHAGTVHAVDVQAAMHERYVEKGLPDN-VQTVTAPIDGLPFEDGALDAAFTTMTYHEFS-GPEAIGEIARVLA 126 9*****************************88877777776.99****************************5.889********** PP EEEEEEE CS Methyltransf_11 89 pgGllvi 95 pgG++v+ tr|M1Y1P2|M1Y1P2_NATM8 127 PGGRVVV 133 ****986 PP >> tr|M1XQ74|M1XQ74_NATM8 Probable S-adenosylmethionine-dependent methyltransferase OS=Natronomonas moolapensis (strain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 50.3 0.0 4.4e-16 4.4e-14 1 86 [. 49 139 .. 49 142 .. 0.95 Alignments for each domain: == domain 1 score: 50.3 bits; conditional E-value: 4.4e-16 EEET-TTSHHHHHHHHTT.SEEEEEES-HHHHHHHHHHCCHHT-.EEETTEECCCT..SS-TT-EEEEEEES-CCC-.CCHHHHHHH CS Methyltransf_11 1 LdvGcGtGrlaealakrg.arvvgvDlspemlklakekaseegl.vefvvadaekl..pfpdnsfDlvvssevlhhv.edpekalke 82 L++GcG+Gr++++l+++g +r+ g+Dl+ ++ e +++ +f+++ +e + f+d+ fD+v+s e+l+h+ +d+e +++e tr|M1XQ74|M1XQ74_NATM8 49 LELGCGSGRHLAHLHEHGfERLSGIDLNGDSFDVMAETYPGLASaGTFHHGAIEAVveGFEDGRFDAVYSVETLQHIhPDVEWVFEE 135 89*********************************9999999989889******96567******************99******** PP HHHH CS Methyltransf_11 83 iaRv 86 iaR+ tr|M1XQ74|M1XQ74_NATM8 136 IARI 139 ***8 PP >> tr|M1XL59|M1XL59_NATM8 Probable S-adenosylmethionine-dependent methyltransferase OS=Natronomonas moolapensis (strain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 45.3 0.0 1.6e-14 1.6e-12 1 86 [. 49 139 .. 49 142 .. 0.93 Alignments for each domain: == domain 1 score: 45.3 bits; conditional E-value: 1.6e-14 EEET-TTSHHHHHHHHTT.SEEEEEES-HHHHHHHHHHCCHHT-.EEETTEECCC.TS.S-TT-EEEEEEES-CCC-.CCHHHHHHH CS Methyltransf_11 1 LdvGcGtGrlaealakrg.arvvgvDlspemlklakekaseegl.vefvvadaek.lp.fpdnsfDlvvssevlhhv.edpekalke 82 L++GcG+Gr++e+l ++g +++ g+D+++++ ++ e++++ + +f + +e+ lp +pd+ +D+v++ e+l+hv +d + +++ tr|M1XL59|M1XL59_NATM8 49 LELGCGSGRHLEHLREQGyESLAGIDINDTAFEVMAEAYPRLAEtGSFTTGALEDvLPgVPDDEYDVVYAVETLQHVhPDEAWVFEA 135 89****************9*********************99999779******95577******************8888889999 PP HHHH CS Methyltransf_11 83 iaRv 86 +aRv tr|M1XL59|M1XL59_NATM8 136 VARV 139 9998 PP >> tr|M1XLC7|M1XLC7_NATM8 Probable S-adenosylmethionine-dependent methyltransferase OS=Natronomonas moolapensis (strain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 44.8 0.0 2.1e-14 2.1e-12 1 78 [. 48 128 .. 48 138 .. 0.91 Alignments for each domain: == domain 1 score: 44.8 bits; conditional E-value: 2.1e-14 EEET-TTSHHHHHHHHTTSEEEEEES-HHHHHHHHHHCCHHT-..EEETTEECCCTSS-TT.-EEEEEEES-CCC-CCHHH CS Methyltransf_11 1 LdvGcGtGrlaealakrgarvvgvDlspemlklakekaseegl..vefvvadaeklpfpdn.sfDlvvssevlhhvedpek 78 +d+G GtG++a ala+ ++rv+g D+s+ ml++a +ka ++g+ v f +++++ ++p++ +D+v+s++++hh+ d ek tr|M1XLC7|M1XLC7_NATM8 48 VDLGTGTGAIALALADDAGRVIGRDISDGMLERAAAKADDAGVpgVAFGPGRFRDPNVPEGvDVDVVTSNFAMHHLSDAEK 128 59*************999*************************************99*99779*************55443 PP >> tr|M1XLH6|M1XLH6_NATM8 Homolog to S-adenosylmethionine-dependent methyltransferase OS=Natronomonas moolapensis (stra # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 43.7 0.0 4.7e-14 4.8e-12 1 80 [. 41 125 .. 41 133 .. 0.87 Alignments for each domain: == domain 1 score: 43.7 bits; conditional E-value: 4.7e-14 EEET-TTSHHHHHHHHTTSEEEEEES-HHHHHHHHHHCCHHT-.EEETTEECCC..TSS-TT-EEEEEEES..-CCC-CCHHHHH CS Methyltransf_11 1 LdvGcGtGrlaealakrgarvvgvDlspemlklakekaseegl.vefvvadaek..lpfpdnsfDlvvsse..vlhhvedpekal 80 Ldv+ GtGr+a +la++g++v +vD+s+e+l++a+++a e+g+ v++++ad+++ ++++ + +Dl+++s+ +l+ ++d+++al tr|M1XLH6|M1XLH6_NATM8 41 LDVATGTGRNALYLAEHGYDVEAVDVSDEALARARRRADERGVdVTWIRADLTDpgFDLETGAYDLITVSFfaALDLLPDLKEAL 125 8****************************************************96678999******999744555556665555 PP >> tr|M1XS10|M1XS10_NATM8 Probable rRNA methyltransferase OS=Natronomonas moolapensis (strain DSM 18674 / JCM 14361 / 8 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 36.5 0.0 8.6e-12 8.6e-10 1 56 [. 59 118 .. 59 126 .. 0.96 Alignments for each domain: == domain 1 score: 36.5 bits; conditional E-value: 8.6e-12 EEET-TTSHHHHHHHHTT.SEEEEEES-HHHHHHHHHHCCHHT-...EEETTEECCCTSS CS Methyltransf_11 1 LdvGcGtGrlaealakrg.arvvgvDlspemlklakekaseegl...vefvvadaeklpf 56 Ld+GcGtG la a rg + vvgvD++p+ l +a+e+ ++ g v++v++d+++lp+ tr|M1XS10|M1XS10_NATM8 59 LDLGCGTGMLALGAALRGpELVVGVDIDPAPLSTARENERRVGAmtdVSWVRGDVTDLPL 118 8**************99**************************9**************97 PP >> tr|M1XRL7|M1XRL7_NATM8 Probable S-adenosylmethionine-dependent methyltransferase PrmC OS=Natronomonas moolapensis (s # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.4 0.0 2.8e-09 2.8e-07 1 66 [. 36 96 .. 36 100 .. 0.85 2 ? 2.4 0.0 0.37 37 78 94 .. 129 145 .. 122 146 .. 0.85 Alignments for each domain: == domain 1 score: 28.4 bits; conditional E-value: 2.8e-09 EEET-TTSHHHHHHHHTT.SEEEEEES-HHHHHHHHHHCCHHT-EEETTEECCCTSS-TT-EEEEEE CS Methyltransf_11 1 LdvGcGtGrlaealakrg.arvvgvDlspemlklakekaseeglvefvvadaeklpfpdnsfDlvvs 66 L+vG+G+G++a +a a+vvg+D++pe+ ++ ++++ e+ v++d+++ ++d sfD+vv tr|M1XRL7|M1XRL7_NATM8 36 LEVGVGSGYVADRIAAETpADVVGCDINPEACRRTRSAGIEA-----VRSDLTHAFLAD-SFDAVVF 96 89*************6666*************7777666554.....9*****955555.*****96 PP == domain 2 score: 2.4 bits; conditional E-value: 0.37 HHHHHHHHHEEEEEEEE CS Methyltransf_11 78 kalkeiaRvLkpgGllv 94 +l+ + RvL+p G+ + tr|M1XRL7|M1XRL7_NATM8 129 PFLSDLGRVLRPSGRAY 145 5788999*******976 PP >> tr|M1XTL7|M1XTL7_NATM8 tRNA (Adenine-N(1))-methyltransferase TrmI OS=Natronomonas moolapensis (strain DSM 18674 / JC # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.7 0.2 1e-08 1e-06 1 94 [. 87 179 .. 87 180 .. 0.83 Alignments for each domain: == domain 1 score: 26.7 bits; conditional E-value: 1e-08 EEET-TTSHHHHHHHHTTSEEEEEES-HHHHHHHHHHCCHHT-...EEETTEECCC.TSS-TT-EEEEEEES-CCC-CCHHHHHHHH CS Methyltransf_11 1 LdvGcGtGrlaealakrgarvvgvDlspemlklakekaseegl...vefvvadaek.lpfpdnsfDlvvssevlhhvedpekalkei 83 Ld+G GtG la++l + g +v++ + ++e+ ++a+e+ ++g+ ++++ +d+++ l+ ++ +Dl ++ d +++++ + tr|M1XTL7|M1XTL7_NATM8 87 LDAGTGTGVLAAYLGRLGVEVTTYERDAEFAAVARENMATAGVaeqIDVRTGDLTDeLDAVEGGYDLLTLDT-----GDAAAVVERA 168 8*****************************************977777788888764555555555554432.....5899999999 PP HHHEEEEEEEE CS Methyltransf_11 84 aRvLkpgGllv 94 +L pgG+l+ tr|M1XTL7|M1XTL7_NATM8 169 DELLAPGGFLA 179 99999999887 PP >> tr|M1XLF5|M1XLF5_NATM8 tRNA (Guanine(10),N(2))-dimethyltransferase OS=Natronomonas moolapensis (strain DSM 18674 / J # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.0 0.0 8.9 9e+02 19 38 .. 20 39 .. 12 76 .. 0.66 2 ! 26.1 0.1 1.5e-08 1.5e-06 1 65 [. 180 245 .. 180 248 .. 0.82 Alignments for each domain: == domain 1 score: -2.0 bits; conditional E-value: 8.9 SEEEEEES-HHHHHHHHHHC CS Methyltransf_11 19 arvvgvDlspemlklakeka 38 +r+ +vDl + +++a+ tr|M1XLF5|M1XLF5_NATM8 20 SRCSAVDLVAPGIATARGVE 39 56666777777666665433 PP == domain 2 score: 26.1 bits; conditional E-value: 1.5e-08 EEET-TTSHHHHHHHHTTSEEEEEES-HHHHHHHHHHCCHHT-..EEETTEECCCTSS-TT-EEEEE CS Methyltransf_11 1 LdvGcGtGrlaealakrgarvvgvDlspemlklakekaseegl..vefvvadaeklpfpdnsfDlvv 65 Ld cGtG ++ + ga+vvgvD ++m++ +++ l +++++da++lp++d+s+D v tr|M1XLF5|M1XLF5_NATM8 180 LDPMCGTGGILVEAGLAGASVVGVDAQAKMVRGTERNLAAY-LgeGSVLRGDATRLPLADDSVDGAV 245 6888***********99**************6554444332.346455****************876 PP >> tr|M1Y5Q2|M1Y5Q2_NATM8 Probable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating) OS=Natronomonas moolap # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.3 0.0 4.6e-07 4.6e-05 2 68 .. 37 103 .. 36 141 .. 0.85 2 ? -1.1 0.0 4.5 4.6e+02 25 25 .. 130 130 .. 103 167 .. 0.49 Alignments for each domain: == domain 1 score: 21.3 bits; conditional E-value: 4.6e-07 EET-TTSHHHHHHHHTTSEEEEEES-HHHHHHHHHHCCHHT-..EEETTEECCCTSS-TT-EEEEEEES CS Methyltransf_11 2 dvGcGtGrlaealakrgarvvgvDlspemlklakekaseegl..vefvvadaeklpfpdnsfDlvvsse 68 +vG++tG+++ + a+ ++rv++++ pe l++ +++ +g+ ve+++++a + +pd D+ ++ tr|M1Y5Q2|M1Y5Q2_NATM8 37 EVGSCTGAVTIEAARLAGRVTAIERKPERLEATRKNLAANGIegVELIEGEAPE-ALPD-DADALFLGG 103 89***************************************99*9999999987.6777.667766655 PP == domain 2 score: -1.1 bits; conditional E-value: 4.5 E CS Methyltransf_11 25 D 25 + tr|M1Y5Q2|M1Y5Q2_NATM8 130 E 130 2 PP >> tr|M1Y3X8|M1Y3X8_NATM8 tRNA (Guanine(37)-N(1))-methyltransferase OS=Natronomonas moolapensis (strain DSM 18674 / JCM # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.3 0.0 4.1e-06 0.00041 5 66 .. 186 250 .. 182 257 .. 0.85 Alignments for each domain: == domain 1 score: 18.3 bits; conditional E-value: 4.1e-06 -TTSHHHHHHHHTTSEEEEEES-HHHHHHHHHHCCHHT-...EEETTEECCCTSS-TT-EEEEEE CS Methyltransf_11 5 cGtGrlaealakrgarvvgvDlspemlklakekaseegl...vefvvadaeklpfpdnsfDlvvs 66 +G G + + akrga++vgvDl+++++++ +++a+++g+ v + ad++++ d+ D +v+ tr|M1Y3X8|M1Y3X8_NATM8 186 AGVGPFIVPAAKRGAECVGVDLNEAAVEYLRRNAERNGVsdrVIAINADVRDVTGYDDWADRIVM 250 699999********************************999866799999998544446666665 PP >> tr|M1Y1T3|M1Y1T3_NATM8 Probable S-adenosylmethionine-dependent methyltransferase OS=Natronomonas moolapensis (strain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.2 0.0 1.9e-05 0.0019 1 94 [. 165 264 .. 165 265 .. 0.80 2 ? -1.9 0.0 8.1 8.2e+02 16 43 .. 361 386 .. 342 402 .. 0.58 Alignments for each domain: == domain 1 score: 16.2 bits; conditional E-value: 1.9e-05 EEET-TTSHHHHHHHHTT.....SEEEEEES-HHHHHHHHHHCCHHT-..EEETTEECCCTSS-TT-EEEEEEES-CCC-CCHHHHH CS Methyltransf_11 1 LdvGcGtGrlaealakrg.....arvvgvDlspemlklakekaseegl..vefvvadaeklpfpdnsfDlvvssevlhhvedpekal 80 LdvG+G+G a l ++ ++ +v++s+++ + + ++++ ++++++ae + p++ +Dlvv +vl +e p ++ tr|M1Y1T3|M1Y1T3_NATM8 165 LDVGAGAGGPALGLYDYLpddslVEYDAVEPSAAADVFETMLDPTRPGfdATVHRETAEAF-APEGEYDLVVFGNVLSELEAPVPVV 250 8**************7777855566666666666664555555555558877799999974.6889********************* PP HHHHHHEEEEEEEE CS Methyltransf_11 81 keiaRvLkpgGllv 94 + L p+G+++ tr|M1Y1T3|M1Y1T3_NATM8 251 ERYLEALAPDGTVL 264 ***********875 PP == domain 2 score: -1.9 bits; conditional E-value: 8.1 HTTSEEEEEES-HHHHHHHHHHCCHHT- CS Methyltransf_11 16 krgarvvgvDlspemlklakekaseegl 43 g+r + D++p + ak++ se+++ tr|M1Y1T3|M1Y1T3_NATM8 361 TDGRRAIEYDPDPGRV--AKMAESERHV 386 4447777777777766..6666666553 PP >> tr|M1XZU1|M1XZU1_NATM8 Protein-L-isoaspartate O-methyltransferase OS=Natronomonas moolapensis (strain DSM 18674 / JC # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.8 0.1 4.9e-05 0.005 1 46 [. 81 132 .. 81 153 .. 0.86 Alignments for each domain: == domain 1 score: 14.8 bits; conditional E-value: 4.9e-05 EEET-TTSHHHHHHHHTT..SEEEEEES-HHHHHHHHHHCCHHT-....EEE CS Methyltransf_11 1 LdvGcGtGrlaealakrg..arvvgvDlspemlklakekaseegl....vef 46 L vG+G G+ a+ la+ a+v g+D++ +++ a+++ s +g v++ tr|M1XZU1|M1XZU1_NATM8 81 LVVGVGVGYTAAVLAELTdeASVHGIDIARRLVYDARSNLSAAGYsgvlVDC 132 679************88889******************99998876655544 PP >> tr|M1XKR6|M1XKR6_NATM8 Modification methylase OS=Natronomonas moolapensis (strain DSM 18674 / JCM 14361 / 8.8.11) OX # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.7 0.0 0.0041 0.41 74 94 .. 67 87 .. 58 88 .. 0.83 2 ? 4.5 0.0 0.085 8.6 4 44 .. 240 280 .. 235 313 .. 0.77 Alignments for each domain: == domain 1 score: 8.7 bits; conditional E-value: 0.0041 CCHHHHHHHHHHHEEEEEEEE CS Methyltransf_11 74 edpekalkeiaRvLkpgGllv 94 e++ek++ke+ RvL gG+ + tr|M1XKR6|M1XKR6_NATM8 67 EELEKVWKEVSRVLIDGGIAC 87 789***************986 PP == domain 2 score: 4.5 bits; conditional E-value: 0.085 T-TTSHHHHHHHHTTSEEEEEES-HHHHHHHHHHCCHHT-..E CS Methyltransf_11 4 GcGtGrlaealakrgarvvgvDlspemlklakekaseegl..v 44 G Gt ++a+ +a g++ vg +l++e+++l ++++++ ++ tr|M1XKR6|M1XKR6_NATM8 240 GTGTTSFAAMVA--GRNSVGYELDEEFVQLFEHRVENVPEysR 280 555555555555..99***************999998876542 PP >> tr|M1Y5X6|M1Y5X6_NATM8 Pyrroline-5-carboxylate reductase OS=Natronomonas moolapensis (strain DSM 18674 / JCM 14361 / # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.4 0.1 0.00014 0.014 3 50 .. 7 57 .. 6 94 .. 0.84 Alignments for each domain: == domain 1 score: 13.4 bits; conditional E-value: 0.00014 ET-T..TSHHHHHHHHTT.SEEEEEES-HHHHHHHHHHCCHHT-EEETTEE CS Methyltransf_11 3 vGcG..tGrlaealakrg.arvvgvDlspemlklakekaseeglvefvvad 50 +GcG +G++++ la+ g ++++++Dl+ e+l++++++a e + + ad tr|M1Y5X6|M1Y5X6_NATM8 7 IGCGnmGGAFLKGLARAGgHHLMAIDLDSEALAAVEAHADETSNDTAAAAD 57 7999888********9999*************9999988887763333333 PP >> tr|M1XP14|M1XP14_NATM8 Protein-L-isoaspartate O-methyltransferase OS=Natronomonas moolapensis (strain DSM 18674 / JC # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.7 0.0 0.00011 0.011 1 51 [. 112 166 .. 112 202 .. 0.86 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 0.00011 EEET-TTSHHHHHHHHTT..SEEEEEES-HHHHHHHHHHCCHHT-..EEETTEEC CS Methyltransf_11 1 LdvGcGtGrlaealakrg..arvvgvDlspemlklakekaseegl..vefvvada 51 L++G G G++a+ a+ + ++v++v++ pe+ + a+++ ++ g v ++ +d tr|M1XP14|M1XP14_NATM8 112 LEIGTGCGYHAAVTAELVgsENVYTVEYVPELAAEARRRLERLGYgdVHVRAGDG 166 899************8888********************9999888777777765 PP >> tr|M1XK62|M1XK62_NATM8 tRNA (guanine(26)-N(2))-dimethyltransferase OS=Natronomonas moolapensis (strain DSM 18674 / J # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.9 0.1 0.0017 0.18 7 47 .. 61 102 .. 55 120 .. 0.75 2 ? 2.0 0.0 0.49 49 12 56 .. 108 151 .. 103 158 .. 0.82 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 0.0017 TSHHHHHHHHTTSEEEEEES-HHHHHHHHHHCCHHT-...EEET CS Methyltransf_11 7 tGrlaealakrgarvvgvDlspemlklakekaseegl...vefv 47 +G a a+ g+ +g+D+++++++la+++ +++gl + + tr|M1XK62|M1XK62_NATM8 61 SGVRAVRAAEAGYAATGCDIDEAAVDLARSNLERNGLsgtI--H 102 667777788999*********************99976432..3 PP == domain 2 score: 2.0 bits; conditional E-value: 0.49 HHHHHTTSEEEEEES-HHHHHHHHHHCCHHT-EEETTEECCCT.SS CS Methyltransf_11 12 ealakrgarvvgvDlspemlklakekaseeglvefvvadaekl.pf 56 ++++++g++vv +D+ + + +a ++ + ++ e+v+ +a+++ p+ tr|M1XK62|M1XK62_NATM8 108 AHMHEHGHDVVDLDPFGTPIPFADAAFRSAR--EYVCVTATDTaPL 151 5678999**************9999999998..7788888876566 PP >> tr|M1XN99|M1XN99_NATM8 tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase OS=Natronomonas moolapen # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.7 0.0 6.9 7e+02 20 32 .. 167 179 .. 153 194 .. 0.69 2 ! 11.5 0.0 0.00055 0.055 5 54 .. 204 256 .. 200 298 .. 0.79 Alignments for each domain: == domain 1 score: -1.7 bits; conditional E-value: 6.9 EEEEEES-HHHHH CS Methyltransf_11 20 rvvgvDlspemlk 32 +++Dls++m tr|M1XN99|M1XN99_NATM8 167 IEYALDLSETMFS 179 6789999999974 PP == domain 2 score: 11.5 bits; conditional E-value: 0.00055 -TTSHHHHHHHHTTSEEEEEES-HHHHHHHHHHCCHHT-...EEETTEECCCT CS Methyltransf_11 5 cGtGrlaealakrgarvvgvDlspemlklakekaseegl...vefvvadaekl 54 +G G+++ ++a+ a+v++ +++p+++++ e+a+++g+ ve v +d++++ tr|M1XN99|M1XN99_NATM8 204 AGIGYFSLPMARAEASVTAAEIDPTAHRRLVENARRNGVaarVEAVLGDCRSV 256 699********999*************99988888888777777777777664 PP >> tr|M1XRN3|M1XRN3_NATM8 Probable ribosomal RNA small subunit methyltransferase A OS=Natronomonas moolapensis (strain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.0 0.00034 0.034 2 58 .. 48 107 .. 47 115 .. 0.90 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 0.00034 EET-TTSHHHHHHHHTTSEEEEEES-HHHHHHHHHHCCHHT-...EEETTEECCCTSS-T CS Methyltransf_11 2 dvGcGtGrlaealakrgarvvgvDlspemlklakekaseegl...vefvvadaeklpfpd 58 ++G GtG l+ l + rv+ v+ +p + ++ +e+ e +++v +da ++++p tr|M1XRN3|M1XRN3_NATM8 48 EIGGGTGGLTDRLLSVADRVTVVERDPDLAAFLREEFAAEIAggtLTVVAGDALEVDLPA 107 89************999********************99999999999****99877764 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (95 nodes) Target sequences: 2723 (809592 residues searched) Passed MSV filter: 129 (0.0473742); expected 54.5 (0.02) Passed bias filter: 115 (0.0422328); expected 54.5 (0.02) Passed Vit filter: 33 (0.012119); expected 2.7 (0.001) Passed Fwd filter: 27 (0.00991553); expected 0.0 (1e-05) Initial search space (Z): 2723 [actual number of targets] Domain search space (domZ): 27 [number of targets reported over threshold] # CPU time: 0.03u 0.00s 00:00:00.03 Elapsed: 00:00:00.02 # Mc/sec: 3845.56 // [ok]