# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/Methyltransf_11.hmm.txt
# target sequence database: proteomes/Saccharomyces_cerevisiae.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: Methyltransf_11 [M=95]
Accession: PF08241.11
Description: Methyltransferase domain
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
4.1e-20 70.7 0.0 8.9e-20 69.6 0.0 1.6 1 sp|P25087|ERG6_YEAST Sterol 24-C-methyltransferase OS=Sacch
7.1e-19 66.7 0.0 1.1e-18 66.1 0.0 1.3 1 sp|P38892|CRG1_YEAST Probable S-adenosylmethionine-dependen
6.8e-14 50.8 0.0 1.7e-13 49.5 0.0 1.7 1 sp|P27680|COQ3_YEAST Ubiquinone biosynthesis O-methyltransf
5.7e-13 47.8 0.0 9.5e-13 47.1 0.0 1.4 1 sp|P25627|BUD23_YEAST 18S rRNA (guanine(1575)-N(7))-methyltr
1.4e-11 43.4 0.0 2.3e-11 42.6 0.0 1.4 1 sp|P49957|TRM9_YEAST tRNA (carboxymethyluridine(34)-5-O)-me
4.6e-10 38.5 0.0 1.3e-09 37.0 0.0 1.8 1 sp|P49017|COQ5_YEAST 2-methoxy-6-polyprenyl-1,4-benzoquinol
5.5e-10 38.2 0.0 1.7e-09 36.7 0.0 1.9 1 sp|Q08641|AB140_YEAST tRNA(Thr) (cytosine(32)-N(3))-methyltr
1.2e-09 37.1 0.0 2.7e-09 36.0 0.0 1.6 1 sp|P32643|TMT1_YEAST Trans-aconitate 3-methyltransferase OS
4.5e-09 35.3 0.0 7.7e-09 34.6 0.0 1.4 1 sp|P40516|EFM4_YEAST Protein-lysine N-methyltransferase EFM
4.9e-09 35.2 0.0 1.2e-08 33.9 0.0 1.7 1 sp|P32783|MCES_YEAST mRNA cap guanine-N7 methyltransferase
7.5e-09 34.6 0.0 2.2e-08 33.1 0.0 1.8 2 sp|P38074|HMT1_YEAST Protein arginine N-methyltransferase 1
1.5e-08 33.6 0.0 1.4e-07 30.6 0.0 2.3 1 sp|Q06668|OMS1_YEAST Methyltransferase OMS1, mitochondrial
4e-08 32.3 0.0 1.5e-07 30.4 0.0 2.1 1 sp|P38961|RRP8_YEAST 25S rRNA (adenine(645)-N(1))-methyltra
7.8e-06 24.9 0.0 1.7e-05 23.8 0.0 1.6 1 sp|P41819|DIM1_YEAST Dimethyladenosine transferase OS=Sacch
1.2e-05 24.3 0.0 0.091 11.9 0.0 2.6 2 sp|P53934|CARME_YEAST Carnosine N-methyltransferase OS=Sacch
0.00014 20.9 0.0 0.00034 19.7 0.0 1.7 1 sp|P38278|BMT2_YEAST 25S rRNA (adenine(2142)-N(1))-methyltr
0.0007 18.7 0.0 0.0034 16.5 0.0 2.2 2 sp|P38321|YB75_YEAST Uncharacterized protein YBR225W OS=Sac
0.00081 18.5 0.0 0.014 14.5 0.0 2.2 2 sp|Q03920|MTQ2_YEAST eRF1 methyltransferase catalytic subun
0.00097 18.2 0.0 0.017 14.3 0.0 2.4 2 sp|P33753|TRM2_YEAST tRNA (uracil(54)-C(5))-methyltransfera
0.0046 16.0 0.0 0.0084 15.2 0.0 1.5 1 sp|P38340|NTM1_YEAST Alpha N-terminal protein methyltransfe
------ inclusion threshold ------
0.068 12.3 0.0 0.2 10.8 0.0 1.9 1 sp|Q12052|TGS1_YEAST Trimethylguanosine synthase OS=Sacchar
Domain annotation for each sequence (and alignments):
>> sp|P25087|ERG6_YEAST Sterol 24-C-methyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=55929
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 69.6 0.0 3.1e-22 8.9e-20 1 95 [] 124 222 .. 124 222 .. 0.95
Alignments for each domain:
== domain 1 score: 69.6 bits; conditional E-value: 3.1e-22
EEET-TTSHHHHHHHHTT.SEEEEEES-HHHHHHHHHHCCHHT-...EEETTEECCCTSS-TT-EEEEEEES-CCC-CCHHHHHHHHHH CS
Methyltransf_11 1 LdvGcGtGrlaealakrg.arvvgvDlspemlklakekaseegl...vefvvadaeklpfpdnsfDlvvssevlhhvedpekalkeiaR 85
LdvGcG G a+++a+ ++v+g++ ++++++ ak a++ +l ++fv++d+ k++f++n+fD v++ e+ +h +++e + +ei++
sp|P25087|ERG6_YEAST 124 LDVGCGVGGPAREIARFTgCNVIGLNNNDYQIAKAKYYAKKYNLsdqMDFVKGDFMKMDFEENTFDKVYAIEATCHAPKLEGVYSEIYK 212
8**************8778*************999888888877999****************************************** PP
HEEEEEEEEE CS
Methyltransf_11 86 vLkpgGllvi 95
vLkpgG++++
sp|P25087|ERG6_YEAST 213 VLKPGGTFAV 222
******9975 PP
>> sp|P38892|CRG1_YEAST Probable S-adenosylmethionine-dependent methyltransferase CRG1 OS=Saccharomyces cerevisiae (str
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 66.1 0.0 4e-21 1.1e-18 1 95 [] 43 140 .. 43 140 .. 0.97
Alignments for each domain:
== domain 1 score: 66.1 bits; conditional E-value: 4e-21
EEET-TTSHHHHHHHHTTSEEEEEES-HHHHHHHHHHCCHHT-...EEETTEECCCT.SS-TT-EEEEEEES-CCC-CCHHHHHHHHHH CS
Methyltransf_11 1 LdvGcGtGrlaealakrgarvvgvDlspemlklakekaseegl...vefvvadaekl.pfpdnsfDlvvssevlhhvedpekalkeiaR 85
+d+GcGtG+ + ++ ++++v+g+D+s +ml +a+++++e++l ++f+ a e+l ++ +s+D+v+s e++h++ ++e++++++
sp|P38892|CRG1_YEAST 43 VDIGCGTGKATFVVEPYFKEVIGIDPSSAMLSIAEKETNERRLdkkIRFINAPGEDLsSIRPESVDMVISAEAIHWC-NLERLFQQVSS 130
59*************999***************************************88******************.6********** PP
HEEEEEEEEE CS
Methyltransf_11 86 vLkpgGllvi 95
+L+ +G++++
sp|P38892|CRG1_YEAST 131 ILRSDGTFAF 140
*******986 PP
>> sp|P27680|COQ3_YEAST Ubiquinone biosynthesis O-methyltransferase, mitochondrial OS=Saccharomyces cerevisiae (strain
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 49.5 0.0 5.7e-16 1.7e-13 1 90 [. 127 219 .. 127 225 .. 0.88
Alignments for each domain:
== domain 1 score: 49.5 bits; conditional E-value: 5.7e-16
EEET-TTSHHHHHHHHTT..SEEEEEES-HHHHHHHHHHCCHHT-....EEETTEECCCTSS-TT-EEEEEEES-CCC-CCHHHHHHHH CS
Methyltransf_11 1 LdvGcGtGrlaealakrg..arvvgvDlspemlklakekaseegl....vefvvadaeklpfpdnsfDlvvssevlhhvedpekalkei 83
LdvGcG+G+l+e la+ ++v g+Dl+ + +ake+a+++++ +++ + +e++ ++fD++++ e+l+hv+ p+++l+ +
sp|P27680|COQ3_YEAST 127 LDVGCGGGILSESLARLKwvKNVQGIDLTRDCIMVAKEHAKKDPMlegkINYECKALEDV---TGQFDIITCMEMLEHVDMPSEILRHC 212
8**************66677************************8877777777777774...58************************ PP
HHHEEEE CS
Methyltransf_11 84 aRvLkpg 90
+ L p+
sp|P27680|COQ3_YEAST 213 WSRLNPE 219
9888885 PP
>> sp|P25627|BUD23_YEAST 18S rRNA (guanine(1575)-N(7))-methyltransferase OS=Saccharomyces cerevisiae (strain ATCC 20450
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 47.1 0.0 3.3e-15 9.5e-13 1 94 [. 52 155 .. 52 156 .. 0.84
Alignments for each domain:
== domain 1 score: 47.1 bits; conditional E-value: 3.3e-15
EEET-TTSHHHHHHHHTT.SEEEEEES-HHHHHHHHHHCCHHT-EEETTEECCC.TSS-TT-EEEEEEES-CCC-...C........C CS
Methyltransf_11 1 LdvGcGtGrlaealakrg.arvvgvDlspemlklakekaseeglvefvvadaek.lpfpdnsfDlvvssevlhhv...e........d 75
Ld+GcG+G+ e l++ g + g+D+sp ml++ ++ e +++ +d+ + +pf+ +sfD+ +s ++++++ + +
sp|P25627|BUD23_YEAST 52 LDIGCGSGLSGEILTQEGdHVWCGLDISPSMLATGLSRELEG---DLMLQDMGTgIPFRAGSFDAAISISAIQWLcnaDtsyndpkqR 136
8*****************88999*********7664444443...34777777659*******************976155566666* PP
HHHHHHHHHHHEEEEEEEE CS
Methyltransf_11 76 pekalkeiaRvLkpgGllv 94
++++++ ++ Lk+gG++v
sp|P25627|BUD23_YEAST 137 LMRFFNTLYAALKKGGKFV 155
*****************98 PP
>> sp|P49957|TRM9_YEAST tRNA (carboxymethyluridine(34)-5-O)-methyltransferase OS=Saccharomyces cerevisiae (strain ATCC
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 42.6 0.0 8.1e-14 2.3e-11 2 94 .. 51 141 .. 50 142 .. 0.88
Alignments for each domain:
== domain 1 score: 42.6 bits; conditional E-value: 8.1e-14
EET-TTSHHHHHHHHTTSEEEEEES-HHHHHHHHHHCCHHT-EEETTEECCCTSS-TT-EEEEEEES-CCC-...CCHHHHHHHHHHHE CS
Methyltransf_11 2 dvGcGtGrlaealakrgarvvgvDlspemlklakekaseeglvefvvadaeklpfpdnsfDlvvssevlhhv...edpekalkeiaRvL 87
dvGcG+G+++ + + ++g D s+ ++++a+ ++ + ++vad +lp ++++fD+ +s +v+hh+ e++ ++++ + L
sp|P49957|TRM9_YEAST 51 DVGCGNGKYLGVNPDIY--IIGSDRSDGLIECARGINPSYN---LLVADGLNLPHKNETFDFAISIAVVHHWstrERRVEVIRHVLSKL 134
9*************777..**************76666554...5***************************88888888888888889 PP
EEEEEEE CS
Methyltransf_11 88 kpgGllv 94
++gG +
sp|P49957|TRM9_YEAST 135 RQGGQAL 141
9999765 PP
>> sp|P49017|COQ5_YEAST 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial OS=Saccharomyces cerevisiae (st
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 37.0 0.0 4.6e-12 1.3e-09 2 95 .] 117 225 .. 116 225 .. 0.84
Alignments for each domain:
== domain 1 score: 37.0 bits; conditional E-value: 4.6e-12
EET-TTSHHHHHHH.....HTT...SEEEEEES-HHHHHHHHHHCCHHT-......EEETTEECCCT.SS-TT-EEEEEEES-CCC-CC CS
Methyltransf_11 2 dvGcGtGrlaeala.....krg...arvvgvDlspemlklakekaseegl......vefvvadaekl.pfpdnsfDlvvssevlhhved 75
dv+ G+G +a l k g ++ vD++p mlk +++a e+g v+f+v++ ekl + ++s D+ ++s+ + ++ d
sp|P49017|COQ5_YEAST 117 DVAGGSGDIAFGLLdhaesKFGdteSTMDIVDINPDMLKEGEKRAMEQGKyfkdprVRFLVSNGEKLeEIDSDSKDIYTVSFGIRNFTD 205
5666666666666634333333665666779*******999999999999999**************78999***************** PP
HHHHHHHHHHHEEEEEEEEE CS
Methyltransf_11 76 pekalkeiaRvLkpgGllvi 95
+k l+ ++RvLkpgG++++
sp|P49017|COQ5_YEAST 206 IQKGLNTAYRVLKPGGIFYC 225
*****************986 PP
>> sp|Q08641|AB140_YEAST tRNA(Thr) (cytosine(32)-N(3))-methyltransferase OS=Saccharomyces cerevisiae (strain ATCC 20450
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 36.7 0.0 5.8e-12 1.7e-09 2 95 .] 439 545 .. 438 545 .. 0.82
Alignments for each domain:
== domain 1 score: 36.7 bits; conditional E-value: 5.8e-12
EET-TTSHHHHHHHHTT....SEEEEEES-HHHHHHHHHHCCHHT-.....EEETTEECC.CTS..S-TT-EEEEEEES-CCC-..CC CS
Methyltransf_11 2 dvGcGtGrlaealakrg....arvvgvDlspemlklakekaseegl.....vefvvadae.klp..fpdnsfDlvvssevlhhv..ed 75
++GcG+G + ++ k r+++ D++p++++l+k+ + ++ v + a+ +lp ++ +s+D+ v+ +v+ + ++
sp|Q08641|AB140_YEAST 439 EIGCGAGNTFFPILKDNenenLRIIAADFAPRAVELVKNSEQFNPKyghatV-WDLANPDgNLPdgVEPHSVDIAVMIFVFSALapNQ 525
79********999955556789***************988888876666531.33333322465567778**************999* PP
HHHHHHHHHHHEEEEEEEEE CS
Methyltransf_11 76 pekalkeiaRvLkpgGllvi 95
+++a+++++++LkpgG++++
sp|Q08641|AB140_YEAST 526 WDQAMDNLHKILKPGGKIIF 545
*****************997 PP
>> sp|P32643|TMT1_YEAST Trans-aconitate 3-methyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 36.0 0.0 9.5e-12 2.7e-09 1 95 [] 41 147 .. 41 147 .. 0.78
Alignments for each domain:
== domain 1 score: 36.0 bits; conditional E-value: 9.5e-12
EEET-TTSHHHHHHHHTT...SEEEEEES-HHHHHHHHHHCCHHT-....EEETTEECCC...TS...S-TT-EEEEEEES-CCC-CCH CS
Methyltransf_11 1 LdvGcGtGrlaealakrg...arvvgvDlspemlklakekaseegl....vefvvadaek...lp...fpdnsfDlvvssevlhhvedp 76
+dvGcG G + ++a+ ++++g Dls++m+k+a+ +++++ v+f ++ + l + ++++D++++ e+ h++ d
sp|P32643|TMT1_YEAST 41 VDVGCGPGTATLQMAQELkpfEQIIGSDLSATMIKTAEVIKEGSPDtyknVSFKISSSDDfkfLGadsVDKQKIDMITAVECAHWF-DF 128
59*************666677*************999655555554567955655555541132223356789*************.7* PP
HHHHHHHHHHEEEEEEEEE CS
Methyltransf_11 77 ekalkeiaRvLkpgGllvi 95
ek+ + ++ L+++G+++i
sp|P32643|TMT1_YEAST 129 EKFQRSAYANLRKDGTIAI 147
***************9975 PP
>> sp|P40516|EFM4_YEAST Protein-lysine N-methyltransferase EFM4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 34.6 0.0 2.7e-11 7.7e-09 1 95 [] 98 208 .. 98 208 .. 0.87
Alignments for each domain:
== domain 1 score: 34.6 bits; conditional E-value: 2.7e-11
EEET-TTSHHHHHHHHTT..SEEEEEES-HHHHHHHHHHCCHHT-...EEETTEECCCTSS-TT-EEEEEEES-CCC-..C........ CS
Methyltransf_11 1 LdvGcGtGrlaealakrg..arvvgvDlspemlklakekaseegl...vefvvadaeklpfpdnsfDlvvssevlhhv..e........ 74
+d+G G+G ++ +l+++ +++vg+D+s+e +kla++ a+ g+ ++f++ad+ + + + +++D+v+ + +l+ +
sp|P40516|EFM4_YEAST 98 VDLGTGNGHMLFELHQTEfqGKLVGIDYSEESVKLASNIAEATGVdnfISFQQADIFSGDWKPGKYDIVLDKGTLDAIslSgmkingkl 186
59*************66668****************888888888889******************************65155566666 PP
.CHHHHHHHHHHHEEEEEEEEE CS
Methyltransf_11 75 .dpekalkeiaRvLkpgGllvi 95
++ + + R+Lk++G+++i
sp|P40516|EFM4_YEAST 187 dVVDVYAGVVERILKKDGIFLI 208
58888888999********986 PP
>> sp|P32783|MCES_YEAST mRNA cap guanine-N7 methyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 33.9 0.0 4.3e-11 1.2e-08 1 94 [. 169 280 .. 169 281 .. 0.85
Alignments for each domain:
== domain 1 score: 33.9 bits; conditional E-value: 4.3e-11
EEET-TTSHHHHHHHHTT.SEEEEEES-HHHHHHHHHHCCHHT-....EEETTEECC......CT.SS-TT-E..EEEEEES-CCC-.. CS
Methyltransf_11 1 LdvGcGtGrlaealakrg.arvvgvDlspemlklakekaseegl....vefvvadae......kl.pfpdnsf..Dlvvssevlhhv.. 73
L++GcG+G ++++ g ++++g+D+s++ ++ a+++++ ++ v ++ +d+ + pfpd f D+v +++lh+
sp|P32783|MCES_YEAST 169 LELGCGKGGDLRKYGAAGiSQFIGIDISNASIQEAHKRYRSMRNldyqVVLITGDCFgeslgvAVePFPDCRFpcDIVSTQFCLHYAfe 257
89*************999************************9966664445555554333333669***75555***********999 PP
..CCHHHHHHHHHHHEEEEEEEE CS
Methyltransf_11 74 ..edpekalkeiaRvLkpgGllv 94
e+ ++al ++a+ Lk gG+++
sp|P32783|MCES_YEAST 258 teEKARRALLNVAKSLKIGGHFF 280
9889****************996 PP
>> sp|P38074|HMT1_YEAST Protein arginine N-methyltransferase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 33.1 0.0 7.8e-11 2.2e-08 1 73 [. 63 138 .. 63 162 .. 0.82
2 ? -2.0 0.0 6.6 1.9e+03 19 28 .. 187 196 .. 177 238 .. 0.74
Alignments for each domain:
== domain 1 score: 33.1 bits; conditional E-value: 7.8e-11
EEET-TTSHHHHHHHHTT.SEEEEEES-HHHHHHHHHHCCHHT-...EEETTEECCCTSS-TT-EEEEEEES-CCC- CS
Methyltransf_11 1 LdvGcGtGrlaealakrg.arvvgvDlspemlklakekaseegl...vefvvadaeklpfpdnsfDlvvssevlhhv 73
LdvGcGtG+l+ ak+g ++v+gvD+s +++ake ++ +g+ ++++++ +e++ +p ++D+++s ++ ++
sp|P38074|HMT1_YEAST 63 LDVGCGTGILSMFAAKHGaKHVIGVDMS-SIIEMAKELVELNGFsdkITLLRGKLEDVHLPFPKVDIIISEWMGYFL 138
8*************************76.5688*******9999999999******96555556******9865554 PP
== domain 2 score: -2.0 bits; conditional E-value: 6.6
SEEEEEES-H CS
Methyltransf_11 19 arvvgvDlsp 28
+v+g+D+sp
sp|P38074|HMT1_YEAST 187 QDVYGFDYSP 196
6788888886 PP
>> sp|Q06668|OMS1_YEAST Methyltransferase OMS1, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 30.6 0.0 4.7e-10 1.4e-07 1 95 [] 246 359 .. 246 359 .. 0.87
Alignments for each domain:
== domain 1 score: 30.6 bits; conditional E-value: 4.7e-10
EEET-TTSHHHHHHH.HTTSEEEEEES-HHHHHHHHHHCCHHT-....EEETTEECCCT.SS-TT.............-EEEEEEES-C CS
Methyltransf_11 1 LdvGcGtGrlaeala.krgarvvgvDlspemlklakekaseegl....vefvvadaekl.pfpdn.............sfDlvvssevl 70
L+v cGtGr+ ++l r +++ +D s++m+++ ++k +e+ + v fvv+ ae+l +++++ ++D +v + l
sp|Q06668|OMS1_YEAST 246 LEVSCGTGRNIKYLDmSRINSITFLDSSENMMEITHKKFREKFPkykkVAFVVGKAENLvDLAEKgkpslenekenqvKYDTIVEAFGL 334
899************6555*************999888888777888999999999987677766666666677788899********* PP
CC-CCHHHHHHHHHHHEEEEEEEEE CS
Methyltransf_11 71 hhvedpekalkeiaRvLkpgGllvi 95
+ edp kal+++ ++Lkp+G++++
sp|Q06668|OMS1_YEAST 335 CSHEDPVKALNNFGKLLKPDGRIIL 359
**********************985 PP
>> sp|P38961|RRP8_YEAST 25S rRNA (adenine(645)-N(1))-methyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 30.4 0.0 5.2e-10 1.5e-07 2 94 .. 205 297 .. 204 298 .. 0.74
Alignments for each domain:
== domain 1 score: 30.4 bits; conditional E-value: 5.2e-10
EET-TTSHHHHHHHHTTSEEEEEES-HHHHHHHHHHCCHHT-......EEETTEECCCTSS-TT-EEEEEEES-CCC-CCHHHHHHHHH CS
Methyltransf_11 2 dvGcGtGrlaealakrgarvvgvDlspemlklakekaseegl......vefvvadaeklpfpdnsfDlvvssevlhhvedpekalkeia 84
d+GcG +la ++ + + + + ++++ k+ k++ + + ++ vad++++p+pd+s+ +vv +l+ + +++ke++
sp|P38961|RRP8_YEAST 205 DMGCGEAQLALEINNFF-KNY----NKKAKKYLKRRHKVHSFdlkkanERITVADIRNVPLPDESCTIVVFCLALMGT-NFLDFIKEAY 287
89999999999999555.222....33333333333333332333355567***************************.59******** PP
HHEEEEEEEE CS
Methyltransf_11 85 RvLkpgGllv 94
R+L p G l+
sp|P38961|RRP8_YEAST 288 RILAPRGELW 297
*******987 PP
>> sp|P41819|DIM1_YEAST Dimethyladenosine transferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=55929
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 23.8 0.0 6e-08 1.7e-05 1 67 [. 61 128 .. 61 138 .. 0.93
Alignments for each domain:
== domain 1 score: 23.8 bits; conditional E-value: 6e-08
EEET-TTSHHHHHHHHTTSEEEEEES-HHHHHHHHHHCCHHT-...EEETTEECCCTSS-TT-EEEEEEE CS
Methyltransf_11 1 LdvGcGtGrlaealakrgarvvgvDlspemlklakekaseegl...vefvvadaeklpfpdnsfDlvvss 67
L+vG GtG l+ + +++++vv+v+++p+m + +++++ ++ +e++ +d+ k+ +p fD+++s+
sp|P41819|DIM1_YEAST 61 LEVGPGTGNLTVRILEQAKNVVAVEMDPRMAAELTKRVRGTPVekkLEIMLGDFMKTELPY--FDICISN 128
89********************************99999999999*99*******988876..9999987 PP
>> sp|P53934|CARME_YEAST Carnosine N-methyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=5592
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 9.5 0.0 0.0017 0.5 3 32 .. 145 174 .. 143 190 .. 0.88
2 ! 11.9 0.0 0.00031 0.091 57 92 .. 264 299 .. 242 301 .. 0.91
Alignments for each domain:
== domain 1 score: 9.5 bits; conditional E-value: 0.0017
ET-TTSHHHHHHHHTTSEEEEEES-HHHHH CS
Methyltransf_11 3 vGcGtGrlaealakrgarvvgvDlspemlk 32
GcGtGrl+ +l + g+++ g ++s +ml
sp|P53934|CARME_YEAST 145 PGCGTGRLLVDLSRMGYNCEGNEFSYHMLL 174
6************************99984 PP
== domain 2 score: 11.9 bits; conditional E-value: 0.00031
-TT-EEEEEEES-CCC-CCHHHHHHHHHHHEEEEEE CS
Methyltransf_11 57 pdnsfDlvvssevlhhvedpekalkeiaRvLkpgGl 92
++ns D+vv ++++++ + ++l+ i vLkpgG+
sp|P53934|CARME_YEAST 264 AENSKDVVVTNFFIDTGSNILDYLDTIGHVLKPGGI 299
589********************************8 PP
>> sp|P38278|BMT2_YEAST 25S rRNA (adenine(2142)-N(1))-methyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 19.7 0.0 1.2e-06 0.00034 47 95 .] 209 263 .. 174 263 .. 0.78
Alignments for each domain:
== domain 1 score: 19.7 bits; conditional E-value: 1.2e-06
TTEECCCTSS-TT...-EEEEEEES-CCC-...CCHHHHHHHHHHHEEEEEEEEE CS
Methyltransf_11 47 vvadaeklpfpdn...sfDlvvssevlhhv...edpekalkeiaRvLkpgGllvi 95
+++d+ + p+p n +fDl+ +s vl++v d+ + + +++ Lkp G+++i
sp|P38278|BMT2_YEAST 209 IKQDFMERPLPRNendKFDLISCSLVLNFVknhRDRGAMCHRMVKFLKPQGYIFI 263
77777775555544469*************7666899999999999******986 PP
>> sp|P38321|YB75_YEAST Uncharacterized protein YBR225W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? -2.4 0.0 9.1 2.6e+03 23 47 .. 428 452 .. 427 462 .. 0.72
2 ! 16.5 0.0 1.2e-05 0.0034 53 94 .. 697 740 .. 680 741 .. 0.92
Alignments for each domain:
== domain 1 score: -2.4 bits; conditional E-value: 9.1
EEES-HHHHHHHHHHCCHHT-EEET CS
Methyltransf_11 23 gvDlspemlklakekaseeglvefv 47
++Dlsp m++ + + a++++ e+
sp|P38321|YB75_YEAST 428 ALDLSPWMIDSSDNDAQNKNASEIA 452
79*******9998887777655444 PP
== domain 2 score: 16.5 bits; conditional E-value: 1.2e-05
CTSS-TT-EEEEEEES-CCC-..CCHHHHHHHHHHHEEEEEEEE CS
Methyltransf_11 53 klpfpdnsfDlvvssevlhhv..edpekalkeiaRvLkpgGllv 94
+lpf+++++ +v++ +v++ + +++++l+ei+R pgG+ +
sp|P38321|YB75_YEAST 697 RLPFASDTIPAVICPWVWTSLsyYKWKALLREIYRSIIPGGYAL 740
59*******************9999****************975 PP
>> sp|Q03920|MTQ2_YEAST eRF1 methyltransferase catalytic subunit MTQ2 OS=Saccharomyces cerevisiae (strain ATCC 204508 /
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 14.5 0.0 4.9e-05 0.014 2 66 .. 48 121 .. 47 144 .. 0.87
2 ? 1.8 0.0 0.45 1.3e+02 77 95 .] 160 178 .. 155 178 .. 0.89
Alignments for each domain:
== domain 1 score: 14.5 bits; conditional E-value: 4.9e-05
EET-TTSHHHHHHHHTT......SEEEEEES-HHHH....HHHHHHCCHHT-EEETTEECCCTSS-TT-EEEEEE CS
Methyltransf_11 2 dvGcGtGrlaealakrg......arvvgvDlspeml....klakekaseeglvefvvadaeklpfpdnsfDlvvs 66
++G+G+G+++ l+++ + ++vD++p +l ++ak ++ ++ ++e+++ad+ + +++n++D+ +
sp|Q03920|MTQ2_YEAST 48 EIGSGSGIVTTFLMQNKiipqenSIHLAVDINPWALeatlDTAKLNSCKSSFLEVIQADLNS-SIRNNQVDVLIF 121
79************5545677678999*****98886666888999999999999******8.9*******9875 PP
== domain 2 score: 1.8 bits; conditional E-value: 0.45
HHHHHHHHHHEEEEEEEEE CS
Methyltransf_11 77 ekalkeiaRvLkpgGllvi 95
+k+l+++ ++L p+G+ +i
sp|Q03920|MTQ2_YEAST 160 DKLLRQLEQILSPDGVAYI 178
689************9875 PP
>> sp|P33753|TRM2_YEAST tRNA (uracil(54)-C(5))-methyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 1.0 0.0 0.81 2.3e+02 20 48 .. 391 421 .. 380 453 .. 0.73
2 ! 14.3 0.0 5.8e-05 0.017 3 54 .. 495 548 .. 493 556 .. 0.89
Alignments for each domain:
== domain 1 score: 1.0 bits; conditional E-value: 0.81
EEEEEES-HHHHHHHHHHCCHHT-..EEETT CS
Methyltransf_11 20 rvvgvDlspemlklakekaseegl..vefvv 48
+++ +D+s+ +l++ e+as++++ +++v+
sp|P33753|TRM2_YEAST 391 NTTILDPSKPTLEQLTEEASRDENgdISYVE 421
6778899999999988888888755533333 PP
== domain 2 score: 14.3 bits; conditional E-value: 5.8e-05
ET-TTSHHHHHHHHTTSEEEEEES-HHHHHHHHHHCCHHT-..EEETTEECCCT CS
Methyltransf_11 3 vGcGtGrlaealakrgarvvgvDlspemlklakekaseegl..vefvvadaekl 54
+ cG+G+++ k + +v+gv++s+ + +a+++a+ +g+ ++f+v+ aekl
sp|P33753|TRM2_YEAST 495 AYCGSGLFSICSSKGVDKVIGVEISADSVSFAEKNAKANGVenCRFIVGKAEKL 548
5599999999888777**********************99999*********97 PP
>> sp|P38340|NTM1_YEAST Alpha N-terminal protein methyltransferase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 /
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 15.2 0.0 2.9e-05 0.0084 1 95 [] 68 169 .. 68 169 .. 0.77
Alignments for each domain:
== domain 1 score: 15.2 bits; conditional E-value: 2.9e-05
EEET-TTSHHHHHHH.HTTSEEEEEES-HHHHHHHHHHCCHHT-....EEETTEECCCTSS-TT-EEEEEEES-CCC-..CCHHHHHHH CS
Methyltransf_11 1 LdvGcGtGrlaeala.krgarvvgvDlspemlklakekaseegl....vefvvadaeklpfpdnsfDlvvssevlhhv..edpekalke 82
+d+G+G Gr+++ + k++a++ v++ + ++++ + + e + ++ + +++ +++ l+++++++ h+ +++ ++lk
sp|P38340|NTM1_YEAST 68 VDIGAGIGRVSKTMLhKHAAKIDLVEPVKPFIEQMHVELAELKDkgqiGQIYEVGMQDWTPDAGKYWLIWCQWCVGHLpdAELVAFLKR 156
59**********99945559999999999999665444433332333345566677776556678889**********98899****** PP
HHHHEEEEEEEEE CS
Methyltransf_11 83 iaRvLkpgGllvi 95
+ L+p+G++v+
sp|P38340|NTM1_YEAST 157 CIVGLQPNGTIVV 169
*********9986 PP
>> sp|Q12052|TGS1_YEAST Trimethylguanosine synthase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 10.8 0.0 0.00069 0.2 1 42 [. 102 143 .. 102 173 .. 0.84
Alignments for each domain:
== domain 1 score: 10.8 bits; conditional E-value: 0.00069
EEET-TTSHHHHHHHHTTSEEEEEES-HHHHHHHHHHCCHHT CS
Methyltransf_11 1 LdvGcGtGrlaealakrgarvvgvDlspemlklakekaseeg 42
Ldv cG+G ++ ++a ++ v+gvD+s e + + ++a+ g
sp|Q12052|TGS1_YEAST 102 LDVFCGGGGNTIQFAMQFPYVYGVDYSIEHIYCTAKNAQSYG 143
7999***********999***********9988877777655 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (95 nodes)
Target sequences: 6049 (2936363 residues searched)
Passed MSV filter: 196 (0.032402); expected 121.0 (0.02)
Passed bias filter: 192 (0.0317408); expected 121.0 (0.02)
Passed Vit filter: 38 (0.00628203); expected 6.0 (0.001)
Passed Fwd filter: 21 (0.00347165); expected 0.1 (1e-05)
Initial search space (Z): 6049 [actual number of targets]
Domain search space (domZ): 21 [number of targets reported over threshold]
# CPU time: 0.05u 0.00s 00:00:00.05 Elapsed: 00:00:00.02
# Mc/sec: 13947.72
//
[ok]