# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/Methyltransf_11.hmm.txt # target sequence database: proteomes/Saccharomyces_cerevisiae.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: Methyltransf_11 [M=95] Accession: PF08241.11 Description: Methyltransferase domain Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.1e-20 70.7 0.0 8.9e-20 69.6 0.0 1.6 1 sp|P25087|ERG6_YEAST Sterol 24-C-methyltransferase OS=Sacch 7.1e-19 66.7 0.0 1.1e-18 66.1 0.0 1.3 1 sp|P38892|CRG1_YEAST Probable S-adenosylmethionine-dependen 6.8e-14 50.8 0.0 1.7e-13 49.5 0.0 1.7 1 sp|P27680|COQ3_YEAST Ubiquinone biosynthesis O-methyltransf 5.7e-13 47.8 0.0 9.5e-13 47.1 0.0 1.4 1 sp|P25627|BUD23_YEAST 18S rRNA (guanine(1575)-N(7))-methyltr 1.4e-11 43.4 0.0 2.3e-11 42.6 0.0 1.4 1 sp|P49957|TRM9_YEAST tRNA (carboxymethyluridine(34)-5-O)-me 4.6e-10 38.5 0.0 1.3e-09 37.0 0.0 1.8 1 sp|P49017|COQ5_YEAST 2-methoxy-6-polyprenyl-1,4-benzoquinol 5.5e-10 38.2 0.0 1.7e-09 36.7 0.0 1.9 1 sp|Q08641|AB140_YEAST tRNA(Thr) (cytosine(32)-N(3))-methyltr 1.2e-09 37.1 0.0 2.7e-09 36.0 0.0 1.6 1 sp|P32643|TMT1_YEAST Trans-aconitate 3-methyltransferase OS 4.5e-09 35.3 0.0 7.7e-09 34.6 0.0 1.4 1 sp|P40516|EFM4_YEAST Protein-lysine N-methyltransferase EFM 4.9e-09 35.2 0.0 1.2e-08 33.9 0.0 1.7 1 sp|P32783|MCES_YEAST mRNA cap guanine-N7 methyltransferase 7.5e-09 34.6 0.0 2.2e-08 33.1 0.0 1.8 2 sp|P38074|HMT1_YEAST Protein arginine N-methyltransferase 1 1.5e-08 33.6 0.0 1.4e-07 30.6 0.0 2.3 1 sp|Q06668|OMS1_YEAST Methyltransferase OMS1, mitochondrial 4e-08 32.3 0.0 1.5e-07 30.4 0.0 2.1 1 sp|P38961|RRP8_YEAST 25S rRNA (adenine(645)-N(1))-methyltra 7.8e-06 24.9 0.0 1.7e-05 23.8 0.0 1.6 1 sp|P41819|DIM1_YEAST Dimethyladenosine transferase OS=Sacch 1.2e-05 24.3 0.0 0.091 11.9 0.0 2.6 2 sp|P53934|CARME_YEAST Carnosine N-methyltransferase OS=Sacch 0.00014 20.9 0.0 0.00034 19.7 0.0 1.7 1 sp|P38278|BMT2_YEAST 25S rRNA (adenine(2142)-N(1))-methyltr 0.0007 18.7 0.0 0.0034 16.5 0.0 2.2 2 sp|P38321|YB75_YEAST Uncharacterized protein YBR225W OS=Sac 0.00081 18.5 0.0 0.014 14.5 0.0 2.2 2 sp|Q03920|MTQ2_YEAST eRF1 methyltransferase catalytic subun 0.00097 18.2 0.0 0.017 14.3 0.0 2.4 2 sp|P33753|TRM2_YEAST tRNA (uracil(54)-C(5))-methyltransfera 0.0046 16.0 0.0 0.0084 15.2 0.0 1.5 1 sp|P38340|NTM1_YEAST Alpha N-terminal protein methyltransfe ------ inclusion threshold ------ 0.068 12.3 0.0 0.2 10.8 0.0 1.9 1 sp|Q12052|TGS1_YEAST Trimethylguanosine synthase OS=Sacchar Domain annotation for each sequence (and alignments): >> sp|P25087|ERG6_YEAST Sterol 24-C-methyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=55929 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 69.6 0.0 3.1e-22 8.9e-20 1 95 [] 124 222 .. 124 222 .. 0.95 Alignments for each domain: == domain 1 score: 69.6 bits; conditional E-value: 3.1e-22 EEET-TTSHHHHHHHHTT.SEEEEEES-HHHHHHHHHHCCHHT-...EEETTEECCCTSS-TT-EEEEEEES-CCC-CCHHHHHHHHHH CS Methyltransf_11 1 LdvGcGtGrlaealakrg.arvvgvDlspemlklakekaseegl...vefvvadaeklpfpdnsfDlvvssevlhhvedpekalkeiaR 85 LdvGcG G a+++a+ ++v+g++ ++++++ ak a++ +l ++fv++d+ k++f++n+fD v++ e+ +h +++e + +ei++ sp|P25087|ERG6_YEAST 124 LDVGCGVGGPAREIARFTgCNVIGLNNNDYQIAKAKYYAKKYNLsdqMDFVKGDFMKMDFEENTFDKVYAIEATCHAPKLEGVYSEIYK 212 8**************8778*************999888888877999****************************************** PP HEEEEEEEEE CS Methyltransf_11 86 vLkpgGllvi 95 vLkpgG++++ sp|P25087|ERG6_YEAST 213 VLKPGGTFAV 222 ******9975 PP >> sp|P38892|CRG1_YEAST Probable S-adenosylmethionine-dependent methyltransferase CRG1 OS=Saccharomyces cerevisiae (str # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 66.1 0.0 4e-21 1.1e-18 1 95 [] 43 140 .. 43 140 .. 0.97 Alignments for each domain: == domain 1 score: 66.1 bits; conditional E-value: 4e-21 EEET-TTSHHHHHHHHTTSEEEEEES-HHHHHHHHHHCCHHT-...EEETTEECCCT.SS-TT-EEEEEEES-CCC-CCHHHHHHHHHH CS Methyltransf_11 1 LdvGcGtGrlaealakrgarvvgvDlspemlklakekaseegl...vefvvadaekl.pfpdnsfDlvvssevlhhvedpekalkeiaR 85 +d+GcGtG+ + ++ ++++v+g+D+s +ml +a+++++e++l ++f+ a e+l ++ +s+D+v+s e++h++ ++e++++++ sp|P38892|CRG1_YEAST 43 VDIGCGTGKATFVVEPYFKEVIGIDPSSAMLSIAEKETNERRLdkkIRFINAPGEDLsSIRPESVDMVISAEAIHWC-NLERLFQQVSS 130 59*************999***************************************88******************.6********** PP HEEEEEEEEE CS Methyltransf_11 86 vLkpgGllvi 95 +L+ +G++++ sp|P38892|CRG1_YEAST 131 ILRSDGTFAF 140 *******986 PP >> sp|P27680|COQ3_YEAST Ubiquinone biosynthesis O-methyltransferase, mitochondrial OS=Saccharomyces cerevisiae (strain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 49.5 0.0 5.7e-16 1.7e-13 1 90 [. 127 219 .. 127 225 .. 0.88 Alignments for each domain: == domain 1 score: 49.5 bits; conditional E-value: 5.7e-16 EEET-TTSHHHHHHHHTT..SEEEEEES-HHHHHHHHHHCCHHT-....EEETTEECCCTSS-TT-EEEEEEES-CCC-CCHHHHHHHH CS Methyltransf_11 1 LdvGcGtGrlaealakrg..arvvgvDlspemlklakekaseegl....vefvvadaeklpfpdnsfDlvvssevlhhvedpekalkei 83 LdvGcG+G+l+e la+ ++v g+Dl+ + +ake+a+++++ +++ + +e++ ++fD++++ e+l+hv+ p+++l+ + sp|P27680|COQ3_YEAST 127 LDVGCGGGILSESLARLKwvKNVQGIDLTRDCIMVAKEHAKKDPMlegkINYECKALEDV---TGQFDIITCMEMLEHVDMPSEILRHC 212 8**************66677************************8877777777777774...58************************ PP HHHEEEE CS Methyltransf_11 84 aRvLkpg 90 + L p+ sp|P27680|COQ3_YEAST 213 WSRLNPE 219 9888885 PP >> sp|P25627|BUD23_YEAST 18S rRNA (guanine(1575)-N(7))-methyltransferase OS=Saccharomyces cerevisiae (strain ATCC 20450 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 47.1 0.0 3.3e-15 9.5e-13 1 94 [. 52 155 .. 52 156 .. 0.84 Alignments for each domain: == domain 1 score: 47.1 bits; conditional E-value: 3.3e-15 EEET-TTSHHHHHHHHTT.SEEEEEES-HHHHHHHHHHCCHHT-EEETTEECCC.TSS-TT-EEEEEEES-CCC-...C........C CS Methyltransf_11 1 LdvGcGtGrlaealakrg.arvvgvDlspemlklakekaseeglvefvvadaek.lpfpdnsfDlvvssevlhhv...e........d 75 Ld+GcG+G+ e l++ g + g+D+sp ml++ ++ e +++ +d+ + +pf+ +sfD+ +s ++++++ + + sp|P25627|BUD23_YEAST 52 LDIGCGSGLSGEILTQEGdHVWCGLDISPSMLATGLSRELEG---DLMLQDMGTgIPFRAGSFDAAISISAIQWLcnaDtsyndpkqR 136 8*****************88999*********7664444443...34777777659*******************976155566666* PP HHHHHHHHHHHEEEEEEEE CS Methyltransf_11 76 pekalkeiaRvLkpgGllv 94 ++++++ ++ Lk+gG++v sp|P25627|BUD23_YEAST 137 LMRFFNTLYAALKKGGKFV 155 *****************98 PP >> sp|P49957|TRM9_YEAST tRNA (carboxymethyluridine(34)-5-O)-methyltransferase OS=Saccharomyces cerevisiae (strain ATCC # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 42.6 0.0 8.1e-14 2.3e-11 2 94 .. 51 141 .. 50 142 .. 0.88 Alignments for each domain: == domain 1 score: 42.6 bits; conditional E-value: 8.1e-14 EET-TTSHHHHHHHHTTSEEEEEES-HHHHHHHHHHCCHHT-EEETTEECCCTSS-TT-EEEEEEES-CCC-...CCHHHHHHHHHHHE CS Methyltransf_11 2 dvGcGtGrlaealakrgarvvgvDlspemlklakekaseeglvefvvadaeklpfpdnsfDlvvssevlhhv...edpekalkeiaRvL 87 dvGcG+G+++ + + ++g D s+ ++++a+ ++ + ++vad +lp ++++fD+ +s +v+hh+ e++ ++++ + L sp|P49957|TRM9_YEAST 51 DVGCGNGKYLGVNPDIY--IIGSDRSDGLIECARGINPSYN---LLVADGLNLPHKNETFDFAISIAVVHHWstrERRVEVIRHVLSKL 134 9*************777..**************76666554...5***************************88888888888888889 PP EEEEEEE CS Methyltransf_11 88 kpgGllv 94 ++gG + sp|P49957|TRM9_YEAST 135 RQGGQAL 141 9999765 PP >> sp|P49017|COQ5_YEAST 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial OS=Saccharomyces cerevisiae (st # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 37.0 0.0 4.6e-12 1.3e-09 2 95 .] 117 225 .. 116 225 .. 0.84 Alignments for each domain: == domain 1 score: 37.0 bits; conditional E-value: 4.6e-12 EET-TTSHHHHHHH.....HTT...SEEEEEES-HHHHHHHHHHCCHHT-......EEETTEECCCT.SS-TT-EEEEEEES-CCC-CC CS Methyltransf_11 2 dvGcGtGrlaeala.....krg...arvvgvDlspemlklakekaseegl......vefvvadaekl.pfpdnsfDlvvssevlhhved 75 dv+ G+G +a l k g ++ vD++p mlk +++a e+g v+f+v++ ekl + ++s D+ ++s+ + ++ d sp|P49017|COQ5_YEAST 117 DVAGGSGDIAFGLLdhaesKFGdteSTMDIVDINPDMLKEGEKRAMEQGKyfkdprVRFLVSNGEKLeEIDSDSKDIYTVSFGIRNFTD 205 5666666666666634333333665666779*******999999999999999**************78999***************** PP HHHHHHHHHHHEEEEEEEEE CS Methyltransf_11 76 pekalkeiaRvLkpgGllvi 95 +k l+ ++RvLkpgG++++ sp|P49017|COQ5_YEAST 206 IQKGLNTAYRVLKPGGIFYC 225 *****************986 PP >> sp|Q08641|AB140_YEAST tRNA(Thr) (cytosine(32)-N(3))-methyltransferase OS=Saccharomyces cerevisiae (strain ATCC 20450 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 36.7 0.0 5.8e-12 1.7e-09 2 95 .] 439 545 .. 438 545 .. 0.82 Alignments for each domain: == domain 1 score: 36.7 bits; conditional E-value: 5.8e-12 EET-TTSHHHHHHHHTT....SEEEEEES-HHHHHHHHHHCCHHT-.....EEETTEECC.CTS..S-TT-EEEEEEES-CCC-..CC CS Methyltransf_11 2 dvGcGtGrlaealakrg....arvvgvDlspemlklakekaseegl.....vefvvadae.klp..fpdnsfDlvvssevlhhv..ed 75 ++GcG+G + ++ k r+++ D++p++++l+k+ + ++ v + a+ +lp ++ +s+D+ v+ +v+ + ++ sp|Q08641|AB140_YEAST 439 EIGCGAGNTFFPILKDNenenLRIIAADFAPRAVELVKNSEQFNPKyghatV-WDLANPDgNLPdgVEPHSVDIAVMIFVFSALapNQ 525 79********999955556789***************988888876666531.33333322465567778**************999* PP HHHHHHHHHHHEEEEEEEEE CS Methyltransf_11 76 pekalkeiaRvLkpgGllvi 95 +++a+++++++LkpgG++++ sp|Q08641|AB140_YEAST 526 WDQAMDNLHKILKPGGKIIF 545 *****************997 PP >> sp|P32643|TMT1_YEAST Trans-aconitate 3-methyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 36.0 0.0 9.5e-12 2.7e-09 1 95 [] 41 147 .. 41 147 .. 0.78 Alignments for each domain: == domain 1 score: 36.0 bits; conditional E-value: 9.5e-12 EEET-TTSHHHHHHHHTT...SEEEEEES-HHHHHHHHHHCCHHT-....EEETTEECCC...TS...S-TT-EEEEEEES-CCC-CCH CS Methyltransf_11 1 LdvGcGtGrlaealakrg...arvvgvDlspemlklakekaseegl....vefvvadaek...lp...fpdnsfDlvvssevlhhvedp 76 +dvGcG G + ++a+ ++++g Dls++m+k+a+ +++++ v+f ++ + l + ++++D++++ e+ h++ d sp|P32643|TMT1_YEAST 41 VDVGCGPGTATLQMAQELkpfEQIIGSDLSATMIKTAEVIKEGSPDtyknVSFKISSSDDfkfLGadsVDKQKIDMITAVECAHWF-DF 128 59*************666677*************999655555554567955655555541132223356789*************.7* PP HHHHHHHHHHEEEEEEEEE CS Methyltransf_11 77 ekalkeiaRvLkpgGllvi 95 ek+ + ++ L+++G+++i sp|P32643|TMT1_YEAST 129 EKFQRSAYANLRKDGTIAI 147 ***************9975 PP >> sp|P40516|EFM4_YEAST Protein-lysine N-methyltransferase EFM4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 34.6 0.0 2.7e-11 7.7e-09 1 95 [] 98 208 .. 98 208 .. 0.87 Alignments for each domain: == domain 1 score: 34.6 bits; conditional E-value: 2.7e-11 EEET-TTSHHHHHHHHTT..SEEEEEES-HHHHHHHHHHCCHHT-...EEETTEECCCTSS-TT-EEEEEEES-CCC-..C........ CS Methyltransf_11 1 LdvGcGtGrlaealakrg..arvvgvDlspemlklakekaseegl...vefvvadaeklpfpdnsfDlvvssevlhhv..e........ 74 +d+G G+G ++ +l+++ +++vg+D+s+e +kla++ a+ g+ ++f++ad+ + + + +++D+v+ + +l+ + sp|P40516|EFM4_YEAST 98 VDLGTGNGHMLFELHQTEfqGKLVGIDYSEESVKLASNIAEATGVdnfISFQQADIFSGDWKPGKYDIVLDKGTLDAIslSgmkingkl 186 59*************66668****************888888888889******************************65155566666 PP .CHHHHHHHHHHHEEEEEEEEE CS Methyltransf_11 75 .dpekalkeiaRvLkpgGllvi 95 ++ + + R+Lk++G+++i sp|P40516|EFM4_YEAST 187 dVVDVYAGVVERILKKDGIFLI 208 58888888999********986 PP >> sp|P32783|MCES_YEAST mRNA cap guanine-N7 methyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.9 0.0 4.3e-11 1.2e-08 1 94 [. 169 280 .. 169 281 .. 0.85 Alignments for each domain: == domain 1 score: 33.9 bits; conditional E-value: 4.3e-11 EEET-TTSHHHHHHHHTT.SEEEEEES-HHHHHHHHHHCCHHT-....EEETTEECC......CT.SS-TT-E..EEEEEES-CCC-.. CS Methyltransf_11 1 LdvGcGtGrlaealakrg.arvvgvDlspemlklakekaseegl....vefvvadae......kl.pfpdnsf..Dlvvssevlhhv.. 73 L++GcG+G ++++ g ++++g+D+s++ ++ a+++++ ++ v ++ +d+ + pfpd f D+v +++lh+ sp|P32783|MCES_YEAST 169 LELGCGKGGDLRKYGAAGiSQFIGIDISNASIQEAHKRYRSMRNldyqVVLITGDCFgeslgvAVePFPDCRFpcDIVSTQFCLHYAfe 257 89*************999************************9966664445555554333333669***75555***********999 PP ..CCHHHHHHHHHHHEEEEEEEE CS Methyltransf_11 74 ..edpekalkeiaRvLkpgGllv 94 e+ ++al ++a+ Lk gG+++ sp|P32783|MCES_YEAST 258 teEKARRALLNVAKSLKIGGHFF 280 9889****************996 PP >> sp|P38074|HMT1_YEAST Protein arginine N-methyltransferase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.1 0.0 7.8e-11 2.2e-08 1 73 [. 63 138 .. 63 162 .. 0.82 2 ? -2.0 0.0 6.6 1.9e+03 19 28 .. 187 196 .. 177 238 .. 0.74 Alignments for each domain: == domain 1 score: 33.1 bits; conditional E-value: 7.8e-11 EEET-TTSHHHHHHHHTT.SEEEEEES-HHHHHHHHHHCCHHT-...EEETTEECCCTSS-TT-EEEEEEES-CCC- CS Methyltransf_11 1 LdvGcGtGrlaealakrg.arvvgvDlspemlklakekaseegl...vefvvadaeklpfpdnsfDlvvssevlhhv 73 LdvGcGtG+l+ ak+g ++v+gvD+s +++ake ++ +g+ ++++++ +e++ +p ++D+++s ++ ++ sp|P38074|HMT1_YEAST 63 LDVGCGTGILSMFAAKHGaKHVIGVDMS-SIIEMAKELVELNGFsdkITLLRGKLEDVHLPFPKVDIIISEWMGYFL 138 8*************************76.5688*******9999999999******96555556******9865554 PP == domain 2 score: -2.0 bits; conditional E-value: 6.6 SEEEEEES-H CS Methyltransf_11 19 arvvgvDlsp 28 +v+g+D+sp sp|P38074|HMT1_YEAST 187 QDVYGFDYSP 196 6788888886 PP >> sp|Q06668|OMS1_YEAST Methyltransferase OMS1, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.6 0.0 4.7e-10 1.4e-07 1 95 [] 246 359 .. 246 359 .. 0.87 Alignments for each domain: == domain 1 score: 30.6 bits; conditional E-value: 4.7e-10 EEET-TTSHHHHHHH.HTTSEEEEEES-HHHHHHHHHHCCHHT-....EEETTEECCCT.SS-TT.............-EEEEEEES-C CS Methyltransf_11 1 LdvGcGtGrlaeala.krgarvvgvDlspemlklakekaseegl....vefvvadaekl.pfpdn.............sfDlvvssevl 70 L+v cGtGr+ ++l r +++ +D s++m+++ ++k +e+ + v fvv+ ae+l +++++ ++D +v + l sp|Q06668|OMS1_YEAST 246 LEVSCGTGRNIKYLDmSRINSITFLDSSENMMEITHKKFREKFPkykkVAFVVGKAENLvDLAEKgkpslenekenqvKYDTIVEAFGL 334 899************6555*************999888888777888999999999987677766666666677788899********* PP CC-CCHHHHHHHHHHHEEEEEEEEE CS Methyltransf_11 71 hhvedpekalkeiaRvLkpgGllvi 95 + edp kal+++ ++Lkp+G++++ sp|Q06668|OMS1_YEAST 335 CSHEDPVKALNNFGKLLKPDGRIIL 359 **********************985 PP >> sp|P38961|RRP8_YEAST 25S rRNA (adenine(645)-N(1))-methyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.4 0.0 5.2e-10 1.5e-07 2 94 .. 205 297 .. 204 298 .. 0.74 Alignments for each domain: == domain 1 score: 30.4 bits; conditional E-value: 5.2e-10 EET-TTSHHHHHHHHTTSEEEEEES-HHHHHHHHHHCCHHT-......EEETTEECCCTSS-TT-EEEEEEES-CCC-CCHHHHHHHHH CS Methyltransf_11 2 dvGcGtGrlaealakrgarvvgvDlspemlklakekaseegl......vefvvadaeklpfpdnsfDlvvssevlhhvedpekalkeia 84 d+GcG +la ++ + + + + ++++ k+ k++ + + ++ vad++++p+pd+s+ +vv +l+ + +++ke++ sp|P38961|RRP8_YEAST 205 DMGCGEAQLALEINNFF-KNY----NKKAKKYLKRRHKVHSFdlkkanERITVADIRNVPLPDESCTIVVFCLALMGT-NFLDFIKEAY 287 89999999999999555.222....33333333333333332333355567***************************.59******** PP HHEEEEEEEE CS Methyltransf_11 85 RvLkpgGllv 94 R+L p G l+ sp|P38961|RRP8_YEAST 288 RILAPRGELW 297 *******987 PP >> sp|P41819|DIM1_YEAST Dimethyladenosine transferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=55929 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.8 0.0 6e-08 1.7e-05 1 67 [. 61 128 .. 61 138 .. 0.93 Alignments for each domain: == domain 1 score: 23.8 bits; conditional E-value: 6e-08 EEET-TTSHHHHHHHHTTSEEEEEES-HHHHHHHHHHCCHHT-...EEETTEECCCTSS-TT-EEEEEEE CS Methyltransf_11 1 LdvGcGtGrlaealakrgarvvgvDlspemlklakekaseegl...vefvvadaeklpfpdnsfDlvvss 67 L+vG GtG l+ + +++++vv+v+++p+m + +++++ ++ +e++ +d+ k+ +p fD+++s+ sp|P41819|DIM1_YEAST 61 LEVGPGTGNLTVRILEQAKNVVAVEMDPRMAAELTKRVRGTPVekkLEIMLGDFMKTELPY--FDICISN 128 89********************************99999999999*99*******988876..9999987 PP >> sp|P53934|CARME_YEAST Carnosine N-methyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=5592 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.5 0.0 0.0017 0.5 3 32 .. 145 174 .. 143 190 .. 0.88 2 ! 11.9 0.0 0.00031 0.091 57 92 .. 264 299 .. 242 301 .. 0.91 Alignments for each domain: == domain 1 score: 9.5 bits; conditional E-value: 0.0017 ET-TTSHHHHHHHHTTSEEEEEES-HHHHH CS Methyltransf_11 3 vGcGtGrlaealakrgarvvgvDlspemlk 32 GcGtGrl+ +l + g+++ g ++s +ml sp|P53934|CARME_YEAST 145 PGCGTGRLLVDLSRMGYNCEGNEFSYHMLL 174 6************************99984 PP == domain 2 score: 11.9 bits; conditional E-value: 0.00031 -TT-EEEEEEES-CCC-CCHHHHHHHHHHHEEEEEE CS Methyltransf_11 57 pdnsfDlvvssevlhhvedpekalkeiaRvLkpgGl 92 ++ns D+vv ++++++ + ++l+ i vLkpgG+ sp|P53934|CARME_YEAST 264 AENSKDVVVTNFFIDTGSNILDYLDTIGHVLKPGGI 299 589********************************8 PP >> sp|P38278|BMT2_YEAST 25S rRNA (adenine(2142)-N(1))-methyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.7 0.0 1.2e-06 0.00034 47 95 .] 209 263 .. 174 263 .. 0.78 Alignments for each domain: == domain 1 score: 19.7 bits; conditional E-value: 1.2e-06 TTEECCCTSS-TT...-EEEEEEES-CCC-...CCHHHHHHHHHHHEEEEEEEEE CS Methyltransf_11 47 vvadaeklpfpdn...sfDlvvssevlhhv...edpekalkeiaRvLkpgGllvi 95 +++d+ + p+p n +fDl+ +s vl++v d+ + + +++ Lkp G+++i sp|P38278|BMT2_YEAST 209 IKQDFMERPLPRNendKFDLISCSLVLNFVknhRDRGAMCHRMVKFLKPQGYIFI 263 77777775555544469*************7666899999999999******986 PP >> sp|P38321|YB75_YEAST Uncharacterized protein YBR225W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.4 0.0 9.1 2.6e+03 23 47 .. 428 452 .. 427 462 .. 0.72 2 ! 16.5 0.0 1.2e-05 0.0034 53 94 .. 697 740 .. 680 741 .. 0.92 Alignments for each domain: == domain 1 score: -2.4 bits; conditional E-value: 9.1 EEES-HHHHHHHHHHCCHHT-EEET CS Methyltransf_11 23 gvDlspemlklakekaseeglvefv 47 ++Dlsp m++ + + a++++ e+ sp|P38321|YB75_YEAST 428 ALDLSPWMIDSSDNDAQNKNASEIA 452 79*******9998887777655444 PP == domain 2 score: 16.5 bits; conditional E-value: 1.2e-05 CTSS-TT-EEEEEEES-CCC-..CCHHHHHHHHHHHEEEEEEEE CS Methyltransf_11 53 klpfpdnsfDlvvssevlhhv..edpekalkeiaRvLkpgGllv 94 +lpf+++++ +v++ +v++ + +++++l+ei+R pgG+ + sp|P38321|YB75_YEAST 697 RLPFASDTIPAVICPWVWTSLsyYKWKALLREIYRSIIPGGYAL 740 59*******************9999****************975 PP >> sp|Q03920|MTQ2_YEAST eRF1 methyltransferase catalytic subunit MTQ2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.5 0.0 4.9e-05 0.014 2 66 .. 48 121 .. 47 144 .. 0.87 2 ? 1.8 0.0 0.45 1.3e+02 77 95 .] 160 178 .. 155 178 .. 0.89 Alignments for each domain: == domain 1 score: 14.5 bits; conditional E-value: 4.9e-05 EET-TTSHHHHHHHHTT......SEEEEEES-HHHH....HHHHHHCCHHT-EEETTEECCCTSS-TT-EEEEEE CS Methyltransf_11 2 dvGcGtGrlaealakrg......arvvgvDlspeml....klakekaseeglvefvvadaeklpfpdnsfDlvvs 66 ++G+G+G+++ l+++ + ++vD++p +l ++ak ++ ++ ++e+++ad+ + +++n++D+ + sp|Q03920|MTQ2_YEAST 48 EIGSGSGIVTTFLMQNKiipqenSIHLAVDINPWALeatlDTAKLNSCKSSFLEVIQADLNS-SIRNNQVDVLIF 121 79************5545677678999*****98886666888999999999999******8.9*******9875 PP == domain 2 score: 1.8 bits; conditional E-value: 0.45 HHHHHHHHHHEEEEEEEEE CS Methyltransf_11 77 ekalkeiaRvLkpgGllvi 95 +k+l+++ ++L p+G+ +i sp|Q03920|MTQ2_YEAST 160 DKLLRQLEQILSPDGVAYI 178 689************9875 PP >> sp|P33753|TRM2_YEAST tRNA (uracil(54)-C(5))-methyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.0 0.0 0.81 2.3e+02 20 48 .. 391 421 .. 380 453 .. 0.73 2 ! 14.3 0.0 5.8e-05 0.017 3 54 .. 495 548 .. 493 556 .. 0.89 Alignments for each domain: == domain 1 score: 1.0 bits; conditional E-value: 0.81 EEEEEES-HHHHHHHHHHCCHHT-..EEETT CS Methyltransf_11 20 rvvgvDlspemlklakekaseegl..vefvv 48 +++ +D+s+ +l++ e+as++++ +++v+ sp|P33753|TRM2_YEAST 391 NTTILDPSKPTLEQLTEEASRDENgdISYVE 421 6778899999999988888888755533333 PP == domain 2 score: 14.3 bits; conditional E-value: 5.8e-05 ET-TTSHHHHHHHHTTSEEEEEES-HHHHHHHHHHCCHHT-..EEETTEECCCT CS Methyltransf_11 3 vGcGtGrlaealakrgarvvgvDlspemlklakekaseegl..vefvvadaekl 54 + cG+G+++ k + +v+gv++s+ + +a+++a+ +g+ ++f+v+ aekl sp|P33753|TRM2_YEAST 495 AYCGSGLFSICSSKGVDKVIGVEISADSVSFAEKNAKANGVenCRFIVGKAEKL 548 5599999999888777**********************99999*********97 PP >> sp|P38340|NTM1_YEAST Alpha N-terminal protein methyltransferase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.2 0.0 2.9e-05 0.0084 1 95 [] 68 169 .. 68 169 .. 0.77 Alignments for each domain: == domain 1 score: 15.2 bits; conditional E-value: 2.9e-05 EEET-TTSHHHHHHH.HTTSEEEEEES-HHHHHHHHHHCCHHT-....EEETTEECCCTSS-TT-EEEEEEES-CCC-..CCHHHHHHH CS Methyltransf_11 1 LdvGcGtGrlaeala.krgarvvgvDlspemlklakekaseegl....vefvvadaeklpfpdnsfDlvvssevlhhv..edpekalke 82 +d+G+G Gr+++ + k++a++ v++ + ++++ + + e + ++ + +++ +++ l+++++++ h+ +++ ++lk sp|P38340|NTM1_YEAST 68 VDIGAGIGRVSKTMLhKHAAKIDLVEPVKPFIEQMHVELAELKDkgqiGQIYEVGMQDWTPDAGKYWLIWCQWCVGHLpdAELVAFLKR 156 59**********99945559999999999999665444433332333345566677776556678889**********98899****** PP HHHHEEEEEEEEE CS Methyltransf_11 83 iaRvLkpgGllvi 95 + L+p+G++v+ sp|P38340|NTM1_YEAST 157 CIVGLQPNGTIVV 169 *********9986 PP >> sp|Q12052|TGS1_YEAST Trimethylguanosine synthase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 0.0 0.00069 0.2 1 42 [. 102 143 .. 102 173 .. 0.84 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.00069 EEET-TTSHHHHHHHHTTSEEEEEES-HHHHHHHHHHCCHHT CS Methyltransf_11 1 LdvGcGtGrlaealakrgarvvgvDlspemlklakekaseeg 42 Ldv cG+G ++ ++a ++ v+gvD+s e + + ++a+ g sp|Q12052|TGS1_YEAST 102 LDVFCGGGGNTIQFAMQFPYVYGVDYSIEHIYCTAKNAQSYG 143 7999***********999***********9988877777655 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (95 nodes) Target sequences: 6049 (2936363 residues searched) Passed MSV filter: 196 (0.032402); expected 121.0 (0.02) Passed bias filter: 192 (0.0317408); expected 121.0 (0.02) Passed Vit filter: 38 (0.00628203); expected 6.0 (0.001) Passed Fwd filter: 21 (0.00347165); expected 0.1 (1e-05) Initial search space (Z): 6049 [actual number of targets] Domain search space (domZ): 21 [number of targets reported over threshold] # CPU time: 0.05u 0.00s 00:00:00.05 Elapsed: 00:00:00.02 # Mc/sec: 13947.72 // [ok]