# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/Methyltransf_11.hmm.txt # target sequence database: proteomes/Trypanosoma_brucei.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: Methyltransf_11 [M=95] Accession: PF08241.11 Description: Methyltransferase domain Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.4e-16 59.1 0.1 3.9e-16 58.4 0.1 1.4 1 tr|Q38DV8|Q38DV8_TRYB2 Ubiquinone biosynthesis O-methyltrans 5.3e-16 58.0 0.0 1.5e-15 56.5 0.0 1.8 1 tr|Q4FKJ2|Q4FKJ2_TRYB2 Methyltransferase OS=Trypanosoma bruc 3.2e-14 52.3 0.0 7.1e-14 51.2 0.0 1.6 1 tr|Q383M8|Q383M8_TRYB2 2-methoxy-6-polyprenyl-1,4-benzoquino 4.7e-14 51.8 0.0 4.5e-12 45.4 0.0 2.9 2 tr|Q57UL4|Q57UL4_TRYB2 Uncharacterized protein OS=Trypanosom 6.5e-13 48.1 0.2 6.6e-12 44.9 0.2 2.3 1 tr|Q38AK8|Q38AK8_TRYB2 Uncharacterized protein OS=Trypanosom 7e-12 44.8 0.0 1.3e-11 43.9 0.0 1.5 1 tr|Q38D36|Q38D36_TRYB2 Uncharacterized protein OS=Trypanosom 2e-10 40.1 0.1 1e-09 37.8 0.1 2.2 2 tr|Q38DL9|Q38DL9_TRYB2 Methyltransferase-like protein OS=Try 2.2e-10 40.0 0.0 4.9e-10 38.9 0.0 1.6 1 tr|Q387X1|Q387X1_TRYB2 Uncharacterized protein OS=Trypanosom 1.5e-09 37.4 0.0 4.1e-05 23.1 0.0 2.7 2 tr|Q38FT0|Q38FT0_TRYB2 Uncharacterized protein OS=Trypanosom 2.3e-09 36.7 0.0 0.00016 21.2 0.0 2.4 2 tr|Q583K3|Q583K3_TRYB2 Uncharacterized protein OS=Trypanosom 3.1e-09 36.3 0.0 6.9e-09 35.2 0.0 1.6 1 tr|Q4GYA9|Q4GYA9_TRYB2 Arginine N-methyltransferase, putativ 5.1e-09 35.6 0.0 7.9e-09 35.0 0.0 1.3 1 tr|Q584S3|Q584S3_TRYB2 Uncharacterized protein OS=Trypanosom 3.7e-08 32.9 0.0 8.4e-08 31.7 0.0 1.6 1 tr|Q57XQ9|Q57XQ9_TRYB2 Uncharacterized protein OS=Trypanosom 1.1e-07 31.4 0.0 2.1e-07 30.4 0.0 1.5 1 tr|Q389B6|Q389B6_TRYB2 Uncharacterized protein OS=Trypanosom 1.3e-06 27.9 0.0 5e-06 26.0 0.0 1.9 1 tr|Q4GZA6|Q4GZA6_TRYB2 Uncharacterized protein OS=Trypanosom 4e-06 26.3 0.0 8.6e-06 25.3 0.0 1.7 1 tr|Q4GZF2|Q4GZF2_TRYB2 Histone-lysine N-methyltransferase, H 6.7e-06 25.6 0.0 9.9e-05 21.9 0.0 2.8 2 tr|Q384Z7|Q384Z7_TRYB2 Uncharacterized protein OS=Trypanosom 9.6e-06 25.1 0.0 2.4e-05 23.8 0.0 1.7 1 tr|Q585P9|Q585P9_TRYB2 rRNA adenine N(6)-methyltransferase O 1.9e-05 24.2 0.0 6.2e-05 22.5 0.0 1.8 1 tr|Q4GYR8|Q4GYR8_TRYB2 Uncharacterized protein OS=Trypanosom 2.5e-05 23.8 0.0 5.8e-05 22.6 0.0 1.7 1 tr|Q584Q2|Q584Q2_TRYB2 DREV methyltransferase, putative OS=T 2.6e-05 23.7 0.0 9.3e-05 22.0 0.0 1.9 1 tr|Q4FKP8|Q4FKP8_TRYB2 mRNA capping methyltransferase, putat 3e-05 23.5 0.0 0.00012 21.6 0.0 2.0 1 tr|Q38EH6|Q38EH6_TRYB2 Spermidine synthase, putative OS=Tryp 0.00012 21.7 0.0 0.00023 20.7 0.0 1.5 1 tr|Q38BP3|Q38BP3_TRYB2 Arginine N-methyltransferase, putativ 0.00015 21.3 0.0 0.00025 20.6 0.0 1.5 1 tr|Q581Z0|Q581Z0_TRYB2 Histone-lysine N-methyltransferase, H 0.00021 20.8 0.1 0.00052 19.6 0.1 1.7 1 tr|Q38AH9|Q38AH9_TRYB2 Protein-L-isoaspartate, putative OS=T 0.00024 20.6 0.1 0.04 13.5 0.0 2.5 2 tr|Q388Y3|Q388Y3_TRYB2 Uncharacterized protein OS=Trypanosom 0.00036 20.1 0.0 0.00096 18.7 0.0 1.8 1 sp|Q582G4|ANM7_TRYB2 Protein arginine N-methyltransferase 0.00042 19.9 0.0 0.027 14.1 0.0 2.4 1 tr|Q38C62|Q38C62_TRYB2 Methyltransferase-like protein OS=Try 0.00054 19.5 0.0 0.0016 18.0 0.0 1.9 1 tr|Q38BY6|Q38BY6_TRYB2 Uncharacterized protein OS=Trypanosom 0.0012 18.4 0.0 0.0034 17.0 0.0 1.8 1 tr|Q57W60|Q57W60_TRYB2 S-adenosyl-methyltransferase mraW-lik 0.0046 16.5 0.1 0.016 14.8 0.1 2.0 1 tr|Q389Z0|Q389Z0_TRYB2 Uncharacterized protein OS=Trypanosom 0.0077 15.8 0.0 0.041 13.5 0.0 2.1 1 tr|Q582P2|Q582P2_TRYB2 Uncharacterized protein OS=Trypanosom 0.0092 15.6 0.0 3.5 7.3 0.0 3.0 3 tr|Q383B4|Q383B4_TRYB2 tRNA (adenine(58)-N(1))-methyltransfe ------ inclusion threshold ------ 0.019 14.5 0.1 0.29 10.8 0.0 2.8 2 tr|Q57W77|Q57W77_TRYB2 Probable methyltransferase BMT2 homol 0.05 13.2 0.0 0.16 11.6 0.0 1.9 1 tr|Q385L0|Q385L0_TRYB2 Uncharacterized protein OS=Trypanosom Domain annotation for each sequence (and alignments): >> tr|Q38DV8|Q38DV8_TRYB2 Ubiquinone biosynthesis O-methyltransferase, mitochondrial OS=Trypanosoma brucei brucei (stra # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 58.4 0.1 1.6e-18 3.9e-16 1 95 [] 71 173 .. 71 173 .. 0.93 Alignments for each domain: == domain 1 score: 58.4 bits; conditional E-value: 1.6e-18 EEET-TTSHHHHHHHHTTSEEEEEES-HHHHHHHHHHCCHHT-.......EEETTEECCCT.SS-TT-EEEEEEES-CCC-CCHHHH CS Methyltransf_11 1 LdvGcGtGrlaealakrgarvvgvDlspemlklakekaseegl.......vefvvadaekl.pfpdnsfDlvvssevlhhvedpeka 79 LdvGcG+G+l+e +a+ g++v+g+D+++e +++a+e+ ++ + +++ ++++ + +f lvv+sev++hv d +++ tr|Q38DV8|Q38DV8_TRYB2 71 LDVGCGGGILSESIARLGGDVLGIDMCKESIAVAEERRQRVLRditpqasLAYRCVPLHEVvEGEGRQFELVVASEVIEHVSDAAAF 157 8*********************************8888776558899999999******97578889******************** PP HHHHHHHEEEEEEEEE CS Methyltransf_11 80 lkeiaRvLkpgGllvi 95 l i kpgG+lvi tr|Q38DV8|Q38DV8_TRYB2 158 LHDICAATKPGGVLVI 173 *************996 PP >> tr|Q4FKJ2|Q4FKJ2_TRYB2 Methyltransferase OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb10.6k1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 56.5 0.0 6.3e-18 1.5e-15 1 94 [. 109 206 .. 109 207 .. 0.98 Alignments for each domain: == domain 1 score: 56.5 bits; conditional E-value: 6.3e-18 EEET-TTSHHHHHHHHTT.SEEEEEES-HHHHHHHHHHCCHHT-...EEETTEECCCTSS-TT-EEEEEEES-CCC-CCHHHHHHHH CS Methyltransf_11 1 LdvGcGtGrlaealakrg.arvvgvDlspemlklakekaseegl...vefvvadaeklpfpdnsfDlvvssevlhhvedpekalkei 83 LdvGcG G a+ + + ++v+gv+ +++++++a+++ s+ g+ +++ + d+ ++ f dn fD ++ e+ +h e k+ +e+ tr|Q4FKJ2|Q4FKJ2_TRYB2 109 LDVGCGIGGPARNMVRFTsCNVMGVNNNEYQINRARQHDSRYGMsgkINYTKTDFCNMCFGDNEFDGAYAIEATCHSESKVKCYSEV 195 8**************8889***********************99******************************************* PP HHHEEEEEEEE CS Methyltransf_11 84 aRvLkpgGllv 94 R kpg +++ tr|Q4FKJ2|Q4FKJ2_TRYB2 196 FRAIKPGAYFM 206 ********997 PP >> tr|Q383M8|Q383M8_TRYB2 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial OS=Trypanosoma brucei brucei # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 51.2 0.0 2.9e-16 7.1e-14 19 94 .. 97 174 .. 86 175 .. 0.94 Alignments for each domain: == domain 1 score: 51.2 bits; conditional E-value: 2.9e-16 SEEEEEES-HHHHHHHHHHCCHHT-..EEETTEECCCTSS-TT-EEEEEEES-CCC-CCHHHHHHHHHHHEEEEEEEE CS Methyltransf_11 19 arvvgvDlspemlklakekaseegl..vefvvadaeklpfpdnsfDlvvssevlhhvedpekalkeiaRvLkpgGllv 94 v+ vD++++m+ +++a +eg +e++va+ e+lp+ d +fD ++s+ l ++ d+ kal+e++RvLk gG+l tr|Q383M8|Q383M8_TRYB2 97 VGVTVVDINEQMVHEGEARAAREGYdgLEWIVASGEELPLDDMQFDGYTVSFGLRNFSDRPKALREAHRVLKVGGVLS 174 56999********99999999999999************************************************986 PP >> tr|Q57UL4|Q57UL4_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.1 0.0 0.3 74 16 41 .. 126 151 .. 113 178 .. 0.69 2 ! 45.4 0.0 1.9e-14 4.5e-12 44 94 .. 283 333 .. 258 334 .. 0.86 Alignments for each domain: == domain 1 score: 3.1 bits; conditional E-value: 0.3 HTTSEEEEEES-HHHHHHHHHHCCHH CS Methyltransf_11 16 krgarvvgvDlspemlklakekasee 41 +++++vv +D sp m++ e++ ++ tr|Q57UL4|Q57UL4_TRYB2 126 NTVTEVVLCDRSPGMIQSTAEQVYRR 151 34499***********7665554444 PP == domain 2 score: 45.4 bits; conditional E-value: 1.9e-14 EEETTEECCCTSS-TT-EEEEEEES-CCC-CCHHHHHHHHHHHEEEEEEEE CS Methyltransf_11 44 vefvvadaeklpfpdnsfDlvvssevlhhvedpekalkeiaRvLkpgGllv 94 +++ ae++pf dnsfD vv + l+ +dp +al+e+ Rv+kp+G+l+ tr|Q57UL4|Q57UL4_TRYB2 283 FSVANYAAEQMPFSDNSFDTVVDMFGLCSYDDPVRALREMSRVCKPDGHLL 333 445777899****************************************97 PP >> tr|Q38AK8|Q38AK8_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 44.9 0.2 2.7e-14 6.6e-12 2 95 .] 71 203 .. 70 203 .. 0.83 Alignments for each domain: == domain 1 score: 44.9 bits; conditional E-value: 2.7e-14 EET-TTSHHHHHHH..................HTT...SEEEEEES-HHHHHHHHHHCCHHT-...............EEETTEECC CS Methyltransf_11 2 dvGcGtGrlaeala..................krg...arvvgvDlspemlklakekaseegl...............vefvvadae 52 dvGcG+G+++ + ++g + v gvD+s+++l+la ++ e e++ ada+ tr|Q38AK8|Q38AK8_TRYB2 71 DVGCGNGKYFSCAQnfmaatsnapddganeegQTGpayRFVAGVDFSERLLRLALNQLDHEASetspsssrslgtrgrTELLLADAR 157 8999999988887778888888887777765544488799***********999555554444466678888888888888****** PP CTSS-TT-EEEEEEES-CCC-...CCHHHHHHHHHHHEEEEEEEEE CS Methyltransf_11 53 klpfpdnsfDlvvssevlhhv...edpekalkeiaRvLkpgGllvi 95 ++ f+++ fD+ +s +v+hh+ e++ +a++e+ R+++p+Gl++i tr|Q38AK8|Q38AK8_TRYB2 158 RTAFRNGAFDAAISIAVVHHFathERRLDAVRELLRLVRPDGLILI 203 *********************9988999**************9975 PP >> tr|Q38D36|Q38D36_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 43.9 0.0 5.3e-14 1.3e-11 1 94 [. 205 301 .. 205 302 .. 0.93 Alignments for each domain: == domain 1 score: 43.9 bits; conditional E-value: 5.3e-14 EEET-TTSHHHHHHHHTTSEEEEEES-HHHHHHHHHHCCHHT-..EEETTEECCCT.SS-TT-EEEEEEES-CCC-CCHHHHHHHHH CS Methyltransf_11 1 LdvGcGtGrlaealakrgarvvgvDlspemlklakekaseegl..vefvvadaekl.pfpdnsfDlvvssevlhhvedpekalkeia 84 L++++G G++ a+ ++++v +D ++++l++ + ++++ ++++ + e+l f+d+ fD+vv + l+ ++dp kal+++ tr|Q38D36|Q38D36_TRYB2 205 LELAAGHGQNIGAYPYAVHEIVMCDANAQQLQAIRYRIPQTAYpkYDVRRVRSENLeMFADGEFDCVVDMFGLCSLHDPLKALRQMQ 291 78999**********778*********************9999887778888889966***************************** PP HHEEEEEEEE CS Methyltransf_11 85 RvLkpgGllv 94 Rv+k Gl++ tr|Q38D36|Q38D36_TRYB2 292 RVVKSSGLIL 301 *******986 PP >> tr|Q38DL9|Q38DL9_TRYB2 Methyltransferase-like protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=18543 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 37.8 0.1 4.2e-12 1e-09 2 95 .] 91 211 .. 90 211 .. 0.83 2 ? -1.8 0.0 9.6 2.4e+03 28 63 .. 269 303 .. 251 304 .. 0.60 Alignments for each domain: == domain 1 score: 37.8 bits; conditional E-value: 4.2e-12 EET-TTSHHHHHHHHTT.....SEEEEEES-HHHHHHHHHHCCHHT-..........EEE.........TTEECC.CT.SS-TT-EE CS Methyltransf_11 2 dvGcGtGrlaealakrg.....arvvgvDlspemlklakekaseegl..........vef.........vvadae.kl.pfpdnsfD 62 ++GcG G + ++ k + rvvg+D+s+ ++kl +ek+++ ++ + + a++ + p d+ +D tr|Q38DL9|Q38DL9_TRYB2 91 EAGCGVGNAVFPILKDYgdvsgWRVVGFDISTVAIKLLREKQNTLPHveqekftawvL-NpveqdiapiITASVArQSrPRGDGLVD 176 78*****999999855559999**********************99977766655550.05555556666666662445******** PP EEEEES-CCC-..CCHHHHHHHHHHHEEEEEEEEE CS Methyltransf_11 63 lvvssevlhhv..edpekalkeiaRvLkpgGllvi 95 +v + +vl+ + e+++ +l+ ia ++k gG++++ tr|Q38DL9|Q38DL9_TRYB2 177 FVSMIFVLCSIpvEEHAVVLRRIAACMKEGGVFFF 211 ***********999******************997 PP == domain 2 score: -1.8 bits; conditional E-value: 9.6 HHHHHHHHHHCCHHT-.....EEETTEECCCT.SS-TT-EEE CS Methyltransf_11 28 pemlklakekaseegl.....vefvvadaekl.pfpdnsfDl 63 ++ + +++++ +f++++++k+ + dn +D+ tr|Q38DL9|Q38DL9_TRYB2 269 EREV-------VNRREgmnlqRRFLQGRFRKIrRIGDNGIDI 303 3333.......2222222333578999999987788888886 PP >> tr|Q387X1|Q387X1_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 38.9 0.0 2e-12 4.9e-10 1 94 [. 63 168 .. 63 169 .. 0.81 Alignments for each domain: == domain 1 score: 38.9 bits; conditional E-value: 2e-12 EEET-TTSHHHHHHH...HTT...SEEEEEES-HHHHHHHHHHCCHHT-..EEE..TTEECCC...TSS-TT-EEEEEEES-CCC-C CS Methyltransf_11 1 LdvGcGtGrlaeala...krg...arvvgvDlspemlklakekaseegl..vef..vvadaek...lpfpdnsfDlvvssevlhhve 74 L+vG+ tG +++++ + ++++ +D+++e l++ e+++ + vef +++d e+ + +p+ ++D+vvs ++h+v+ tr|Q387X1|Q387X1_TRYB2 63 LEVGAHTGWFFRHMLekqQ-LfglKQYIQTDVCEERLNRNYEEIKHLIPpdVEFvqICCDEEEpspFGIPERTVDMVVSCLSMHWVN 148 799***********97642.268**************7776666666557855533566666643355899**************** PP CHHHHHHHHHHHEEEEEEEE CS Methyltransf_11 75 dpekalkeiaRvLkpgGllv 94 d+e a+ +i++vLk++G+l+ tr|Q387X1|Q387X1_TRYB2 149 DLETAMVNIRKVLKKDGFLM 168 *****************986 PP >> tr|Q38FT0|Q38FT0_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.1 0.0 1.7e-07 4.1e-05 1 43 [. 140 182 .. 140 209 .. 0.84 2 ! 11.4 0.0 0.00073 0.18 59 95 .] 261 297 .. 236 297 .. 0.86 Alignments for each domain: == domain 1 score: 23.1 bits; conditional E-value: 1.7e-07 EEET-TTSHHHHHHHHTTSEEEEEES-HHHHHHHHHHCCHHT- CS Methyltransf_11 1 LdvGcGtGrlaealakrgarvvgvDlspemlklakekaseegl 43 Ld+Gc G+ + ++ k+++rvvg+D+s +++k+a++ ++ + + tr|Q38FT0|Q38FT0_TRYB2 140 LDLGCAVGASSLEMSKYFSRVVGIDYSVAFIKMARNVVQSALN 182 8*********************************987776544 PP == domain 2 score: 11.4 bits; conditional E-value: 0.00073 T-EEEEEEES-CCC-CCHHHHHHHHHHHEEEEEEEEE CS Methyltransf_11 59 nsfDlvvssevlhhvedpekalkeiaRvLkpgGllvi 95 + fD+v++ + l+ v++p+k+l+ + +L gG+lvi tr|Q38FT0|Q38FT0_TRYB2 261 ERFDAVLVANLLCRVPNPRKLLDMLPLLLVSGGILVI 297 69********************************996 PP >> tr|Q583K3|Q583K3_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.2 0.0 6.5e-07 0.00016 1 38 [. 56 93 .. 56 115 .. 0.88 2 ! 13.2 0.0 0.00021 0.051 43 90 .. 152 213 .. 137 218 .. 0.73 Alignments for each domain: == domain 1 score: 21.2 bits; conditional E-value: 6.5e-07 EEET-TTSHHHHHHHHTTSEEEEEES-HHHHHHHHHHC CS Methyltransf_11 1 LdvGcGtGrlaealakrgarvvgvDlspemlklakeka 38 LdvGcG+G+ e l + g++ +g+D+s+ ml +ak+ tr|Q583K3|Q583K3_TRYB2 56 LDVGCGSGLSGEVLRECGHTWIGIDISTDMLGMAKASE 93 8**************999*************9997654 PP == domain 2 score: 13.2 bits; conditional E-value: 0.00021 -..EEETTEECCC.TSS-TT-EEEEEEES-CCC-...C........CHHHHHHHHHHHEEEE CS Methyltransf_11 43 l..vefvvadaek.lpfpdnsfDlvvssevlhhv...e........dpekalkeiaRvLkpg 90 + ve++++d+ + lpf+ + fD vs ++++++ + +++++++ ++ L+ g tr|Q583K3|Q583K3_TRYB2 152 PsiVEVMRGDMGEgLPFRPGAFDGAVSISAVQWLcqsDrrgqvpqrRLRALFQCLYNALRRG 213 14589999**99879*******************8652445555556666666666666666 PP >> tr|Q4GYA9|Q4GYA9_TRYB2 Arginine N-methyltransferase, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 35.2 0.0 2.8e-11 6.9e-09 1 69 [. 58 128 .. 58 142 .. 0.88 Alignments for each domain: == domain 1 score: 35.2 bits; conditional E-value: 2.8e-11 EEET-TTSHHHHHHHHTT.SEEEEEES-HHHHHHHHHHCCHHT-...EEETTEECCCTSS-TT-EEEEEEES- CS Methyltransf_11 1 LdvGcGtGrlaealakrg.arvvgvDlspemlklakekaseegl...vefvvadaeklpfpdnsfDlvvssev 69 LdvGcGtG+l+ ak g ++v+gvD s+ ++ +a+e ++++g+ ++++++ +e++++ + ++D+++s ++ tr|Q4GYA9|Q4GYA9_TRYB2 58 LDVGCGTGILSMFAAKAGaRKVIGVDCSTVAV-QAREIVRDNGFedvITIIQGKVEEIQLDE-KVDIIISEWM 128 8*************************999999.7778888887788899*********9955.******9876 PP >> tr|Q584S3|Q584S3_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 35.0 0.0 3.2e-11 7.9e-09 1 95 [] 94 191 .. 94 191 .. 0.94 Alignments for each domain: == domain 1 score: 35.0 bits; conditional E-value: 3.2e-11 EEET-TTSHHHHHHHHTTSEEEE.EES-HHHHHHHHHHCCHHT-EEETTEECCCTSS-TT-EEEEEEES-CCC-..CCHHHHHHHHH CS Methyltransf_11 1 LdvGcGtGrlaealakrgarvvg.vDlspemlklakekaseeglvefvvadaeklpfpdnsfDlvvssevlhhv..edpekalkeia 84 Ld+G+G Gr+++ l + ++v+ +++ + ml+ ake+ ++ ++ +f ++++e+ +++ +++Dl+v++++ ++ ed ++l ++ tr|Q584S3|Q584S3_TRYB2 94 LDCGAGIGRITKSLLCHLYDVTDlLEPVASMLEKAKEELEGFPVGDFFQSSMETAKLQPKTYDLIVIQWAAIYLtdEDFVAFLVRCK 180 8**************7777777527****************999999***************************999********** PP HHEEEEEEEEE CS Methyltransf_11 85 RvLkpgGllvi 95 L p G++++ tr|Q584S3|Q584S3_TRYB2 181 EALTPKGYIFF 191 ********997 PP >> tr|Q57XQ9|Q57XQ9_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 31.7 0.0 3.4e-10 8.4e-08 1 94 [. 47 158 .. 47 159 .. 0.84 Alignments for each domain: == domain 1 score: 31.7 bits; conditional E-value: 3.4e-10 EEET-TTSHHHHHHHHTT..SEEEEEES-HHHHHHHHHHCCHHT-EEETTEECCC.........TSS-TT-EEEEEEES-CCC-... CS Methyltransf_11 1 LdvGcGtGrlaealakrg..arvvgvDlspemlklakekaseeglvefvvadaek.........lpfpdnsfDlvvssevlhhv... 73 L vGcG+ rl+ + ++ +++++vD+sp+++ + +++++ ++++++++d+ + l +d+ fD+v+ + ++ tr|Q57XQ9|Q57XQ9_TRYB2 47 LVVGCGNSRLSPCMYEHLnvRKITNVDVSPTVISQMTRRYKGMDEMRWICCDLIHtapdklltlLCPEDALFDFVIDKGLVDATlgg 133 679************88889*************9999999999998887777775333334332336899*********99988888 PP ....CCHHHHHHHHHHHEEEEEEEE CS Methyltransf_11 74 ....edpekalkeiaRvLkpgGllv 94 +++ + k++aRv+k+gG+++ tr|Q57XQ9|Q57XQ9_TRYB2 134 snsfHNLYTLTKNLARVMKNGGRFL 158 88889*****************985 PP >> tr|Q389B6|Q389B6_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.4 0.0 8.6e-10 2.1e-07 1 71 [. 114 188 .. 114 201 .. 0.86 Alignments for each domain: == domain 1 score: 30.4 bits; conditional E-value: 8.6e-10 EEET-TTSHHHHHHHHTTSEEEEEES-HHHH....HHHHHHCCHHT-EEETTEECCCT.SS-TT-EEEEEEES-CC CS Methyltransf_11 1 LdvGcGtGrlaealakrgarvvgvDlspeml....klakekaseeglvefvvadaekl.pfpdnsfDlvvssevlh 71 Ld+G+G+Gr + la rg +vvg++ +++ +la+++ + + v ++++d+++ p++++s+Dlv + +lh tr|Q389B6|Q389B6_TRYB2 114 LDIGSGSGRDMVFLASRGWHVVGIENRRRLIwqgeTLARKHDVSGR-VAYLHSDIKEAyPVRSGSVDLVHVCRFLH 188 8*****************************9555445555555544.99*******966***********999998 PP >> tr|Q4GZA6|Q4GZA6_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=TB # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.0 0.0 2.1e-08 5e-06 2 90 .. 222 296 .. 221 300 .. 0.90 Alignments for each domain: == domain 1 score: 26.0 bits; conditional E-value: 2.1e-08 EET-TTSHHHHHHHHTTSEEEEEES-HHHHHHHHHHCCHHT-EEETTEECCCTSS-TT-EEEEEEES-CCC-CCHHHHHHHHHHHEE CS Methyltransf_11 2 dvGcGtGrlaealakrgarvvgvDlspemlklakekaseeglvefvvadaeklpfpdnsfDlvvssevlhhvedpekalkeiaRvLk 88 d+GcG ++a+al +g++v +Dl +m +++ va++ ++p++++s+D+++ s +l+ d k+l e+ R+Lk tr|Q4GZA6|Q4GZA6_TRYB2 222 DMGCGDAQVAQALCPKGYTVHSFDLH-AMNEYV------------TVANIAHVPLEKKSVDICIFSLSLMST-DYIKCLYEAFRILK 294 99**********************74.444333............89************************9.799*********** PP EE CS Methyltransf_11 89 pg 90 p tr|Q4GZA6|Q4GZA6_TRYB2 295 PK 296 96 PP >> tr|Q4GZF2|Q4GZF2_TRYB2 Histone-lysine N-methyltransferase, H3 lysine-79 specific OS=Trypanosoma brucei brucei (strai # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.3 0.0 3.5e-08 8.6e-06 2 66 .. 117 193 .. 116 224 .. 0.79 Alignments for each domain: == domain 1 score: 25.3 bits; conditional E-value: 3.5e-08 EET-TTSHHHHHHH.HTTSEEEEEES-HHHHHHHHHHCCHHT-...........EEETTEECCCTSS-TT-EEEEEE CS Methyltransf_11 2 dvGcGtGrlaeala.krgarvvgvDlspemlklakekaseegl...........vefvvadaeklpfpdnsfDlvvs 66 d+GcG+G+++ ++a +ga++vgv+++++ k+ake+ ++ v++v++d+ k+ +dn+f ++ tr|Q4GZF2|Q4GZF2_TRYB2 117 DLGCGNGSVLFHVAlATGASCVGVEINEHNAKVAKEAWTHLRPvfekrrgrkldVSIVCGDFCKVLKQDNYFSSSCV 193 9*************8888****************88887777778888888888999******99889998865444 PP >> tr|Q384Z7|Q384Z7_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.3 0.0 3.3 8.1e+02 44 59 .. 503 518 .. 482 522 .. 0.83 2 ! 21.9 0.0 4e-07 9.9e-05 2 94 .. 820 931 .. 819 932 .. 0.84 Alignments for each domain: == domain 1 score: -0.3 bits; conditional E-value: 3.3 EEETTEECCCTSS-TT CS Methyltransf_11 44 vefvvadaeklpfpdn 59 ++f +ad+++lpfp+ tr|Q384Z7|Q384Z7_TRYB2 503 LSFEEADVRELPFPER 518 7899*********986 PP == domain 2 score: 21.9 bits; conditional E-value: 4e-07 EET-TTSHHHHHHHHTT.SEEEEEES-HHHHHHHHHHCCHHT-.......EEETTEECCC.......T.SS-TT-EEEEEEES-CCC CS Methyltransf_11 2 dvGcGtGrlaealakrg.arvvgvDlspemlklakekaseegl.......vefvvadaek.......l.pfpdnsfDlvvssevlhh 72 ++ c++G+l++++ ++ ar++g+Dl ++++a+e +s ++ ++++ad+ + l ++ +f ++++++ +hh tr|Q384Z7|Q384Z7_TRYB2 820 EI-CCGGYLLRKWIRNKtARYIGFDLKSSVVDAASELISSLRHemtemsfYDVICADVFSanfwshhLtKIHPRQFHVITAFAGFHH 905 66.677888888886666****************9999999999999888777999998533444445467888************* PP -....CCHHHHHHHHHHHEEEEEEEE CS Methyltransf_11 73 v....edpekalkeiaRvLkpgGllv 94 +++++ +a L pgG+++ tr|Q384Z7|Q384Z7_TRYB2 906 AfgteYTAMRLIESVANALIPGGVFI 931 *999889****************997 PP >> tr|Q585P9|Q585P9_TRYB2 rRNA adenine N(6)-methyltransferase OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX= # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.8 0.0 9.8e-08 2.4e-05 1 65 [. 93 158 .. 93 173 .. 0.89 Alignments for each domain: == domain 1 score: 23.8 bits; conditional E-value: 9.8e-08 EEET-TTSHHHHHHHHTTSEEEEEES-HHHHHHHHHHCCHHT-...EEETTEECCCTSS-TT-EEEEE CS Methyltransf_11 1 LdvGcGtGrlaealakrgarvvgvDlspemlklakekaseegl...vefvvadaeklpfpdnsfDlvv 65 L++G GtG l+e+l + +++v++++++p+m++ +++ ++++l ++++++++ + fp fD +v tr|Q585P9|Q585P9_TRYB2 93 LEIGPGTGNLTEKLLQAAKKVIAFEVDPRMVAELNKRFQNSPLapkLQVIRGNCLDHEFPY--FDKCV 158 89*************999************************9*99888999998877764..66555 PP >> tr|Q4GYR8|Q4GYR8_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=TB # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.5 0.0 2.5e-07 6.2e-05 1 54 [. 401 456 .. 401 462 .. 0.95 Alignments for each domain: == domain 1 score: 22.5 bits; conditional E-value: 2.5e-07 EEET-TTSHHHHHHHHTTSEEEEEES-HHHHHHHHHHCCHHT-..EEETTEECCCT CS Methyltransf_11 1 LdvGcGtGrlaealakrgarvvgvDlspemlklakekaseegl..vefvvadaekl 54 Ld+ cGtG + alak+++rv+g++l + +++ a+ +a+++g+ +f ++++e+l tr|Q4GYR8|Q4GYR8_TRYB2 401 LDLCCGTGTIGIALAKHVKRVIGIELVESAVRDARLNAERNGVrnATFNCGRVEHL 456 89****************************************999999******97 PP >> tr|Q584Q2|Q584Q2_TRYB2 DREV methyltransferase, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.6 0.0 2.4e-07 5.8e-05 1 94 [. 123 213 .. 123 214 .. 0.86 Alignments for each domain: == domain 1 score: 22.6 bits; conditional E-value: 2.4e-07 EEET-TTSHHHHHHHHTTSEEEEEES-HHHHHHHHHHCCHHT-EEETTEECCCTSS-TT-EEEEEEES-CCC-CCHHHHHHHHHHHE CS Methyltransf_11 1 LdvGcGtGrlaealakrgarvvgvDlspemlklakekaseeglvefvvadaeklpfpdnsfDlvvssevlhhvedpekalkeiaRvL 87 LdvG+G G ++ l+ ++rv+++++s m+ + ++++ e + + +++ + ++D++ + +vl+ ++p ++l+ ++ L tr|Q584Q2|Q584Q2_TRYB2 123 LDVGAGDGGVTSRLQPLFKRVTATEFSIPMRWRLWRRGYEVLP---YQDPFTNKDGSRRYYDVISCLNVLDRADRPLDLLASMRDSL 206 8******************************555555544432...5666776667778**************************** PP EEEEEEE CS Methyltransf_11 88 kpgGllv 94 p+G+l+ tr|Q584Q2|Q584Q2_TRYB2 207 GPEGILL 213 ****997 PP >> tr|Q4FKP8|Q4FKP8_TRYB2 mRNA capping methyltransferase, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.0 0.0 3.8e-07 9.3e-05 18 94 .. 107 201 .. 92 202 .. 0.77 Alignments for each domain: == domain 1 score: 22.0 bits; conditional E-value: 3.8e-07 TSEEEEEES-HHHHHHHHHHCCHHT-..........EEETTEECC..CTSS-T..T-EEEEEEES-CCC-....CCHHHHHHHHHHH CS Methyltransf_11 18 garvvgvDlspemlklakekaseegl..........vefvvadae..klpfpd..nsfDlvvssevlhhv....edpekalkeiaRv 86 +a v + D+spe ++ a++++++ + ++ +d+ +lp+ ++fD+v +++++h+ e+ + +l iaR tr|Q4FKP8|Q4FKP8_TRYB2 107 AAYVECYDVSPECIAEAESRYKKIAPdtvcrcsftvKDCFSEDFLlrELPLTQhfGKFDIVSIQFAFHYAcdtlERIDMLLGAIARA 193 3688999*******999999998888888774433323344443344699999556**************999999*********** PP EEEEEEEE CS Methyltransf_11 87 LkpgGllv 94 L p+G+++ tr|Q4FKP8|Q4FKP8_TRYB2 194 LAPEGVFI 201 ******98 PP >> tr|Q38EH6|Q38EH6_TRYB2 Spermidine synthase, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.6 0.0 4.8e-07 0.00012 3 94 .. 94 199 .. 92 200 .. 0.86 Alignments for each domain: == domain 1 score: 21.6 bits; conditional E-value: 4.8e-07 ET-TTSHHHHHHHHTT..SEEEEEES-HHHHHHHHHHCCHHT-......EEETTEECCCT..SS-TT-EEEEEEES......-CCC- CS Methyltransf_11 3 vGcGtGrlaealakrg..arvvgvDlspemlklakekaseegl......vefvvadaekl..pfpdnsfDlvvsse......vlhhv 73 +G G G +++++ ++g +r+v vD++ +++++k+ ++ +++v+d + +++sfD+v++ + + + tr|Q38EH6|Q38EH6_TRYB2 94 IGGGDGGVMREVLRHGtvKRCVLVDIDGDVIEASKKYFPQISSgfsdprADVRVGDGVAFvrEAASESFDVVIIDTtdpdgpAAELF 180 899**********999***************99988887776699999978899999985457999********9967776666666 PP CCHHHHHHHHHHHEEEEEEEE CS Methyltransf_11 74 edpekalkeiaRvLkpgGllv 94 ek+ + + R+Lkp G+++ tr|Q38EH6|Q38EH6_TRYB2 181 --GEKFYRDVLRILKPRGICC 199 ..69**************995 PP >> tr|Q38BP3|Q38BP3_TRYB2 Arginine N-methyltransferase, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.7 0.0 9.4e-07 0.00023 1 74 [. 146 224 .. 146 246 .. 0.73 Alignments for each domain: == domain 1 score: 20.7 bits; conditional E-value: 9.4e-07 EEET-TTSHHHHHHHHTT.SEEEEEES-HHHHHHHHHHCCHHT-..EEETTEECCCT..SS-TT-EEEEEEES-CCC-.C CS Methyltransf_11 1 LdvGcGtGrlaealakrg.arvvgvDlspemlklakekaseegl..vefvvadaekl..pfpdnsfDlvvssevlhhv.e 74 L++GcG G+++ a+ + vv+vD s+ + +a+ a+++gl ++f ++ + ++ +fp +fD++++ ++ ++ + tr|Q38BP3|Q38BP3_TRYB2 146 LHLGCGMGLVSMIAARSLaSAVVAVDRSAIVD-AAQVVAKKNGLnnISFFRGALVDVvqNFPVRQFDVIICEWMGPFLiN 224 789************8888*******998876.444444444445578888877774457***********998666652 PP >> tr|Q581Z0|Q581Z0_TRYB2 Histone-lysine N-methyltransferase, H3 lysine-79 specific OS=Trypanosoma brucei brucei (strai # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.6 0.0 1e-06 0.00025 2 38 .. 134 171 .. 133 242 .. 0.82 Alignments for each domain: == domain 1 score: 20.6 bits; conditional E-value: 1e-06 EET-TTSHHHHHHH.HTTSEEEEEES-HHHHHHHHHHC CS Methyltransf_11 2 dvGcGtGrlaeala.krgarvvgvDlspemlklakeka 38 d+GcG+G+++ ++a +gar+vg+++s++ k+ak++ tr|Q581Z0|Q581Z0_TRYB2 134 DLGCGNGSILFQVAfLTGARCVGIEISEHNAKVAKKAW 171 9*************8888**************998764 PP >> tr|Q38AH9|Q38AH9_TRYB2 Protein-L-isoaspartate, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.6 0.1 2.1e-06 0.00052 1 74 [. 93 181 .. 93 196 .. 0.71 Alignments for each domain: == domain 1 score: 19.6 bits; conditional E-value: 2.1e-06 EEET-TTSHHHHHHHHTT....SEEEEEES-HHHHHHHHHHCCHHT-........EEETTEECCCT.S.S-TT..-EEEEEEES-CC CS Methyltransf_11 1 LdvGcGtGrlaealakrg....arvvgvDlspemlklakekaseegl........vefvvadaekl.p.fpdn..sfDlvvssevlh 71 LdvG+G+G+l++ la+ + ++v+gv+ e++ ++ ++++++++ ++f+++d +++ + + fD++ + ++ tr|Q38AH9|Q38AH9_TRYB2 93 LDVGSGSGYLTAVLAELCsgrgGTVIGVEHISELVVRS-TEVVNKHFrswveegrIKFIEGDGRNItGlLGQKvpDFDVIHVGAAAA 178 8**************7777788*******999999333.3444444456667999*********95333222233699998888777 PP C-C CS Methyltransf_11 72 hve 74 +v+ tr|Q38AH9|Q38AH9_TRYB2 179 TVP 181 774 PP >> tr|Q388Y3|Q388Y3_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.5 0.0 0.00016 0.04 2 55 .. 42 112 .. 41 121 .. 0.85 2 ? 4.6 0.1 0.1 25 59 74 .. 145 160 .. 119 171 .. 0.80 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 0.00016 EET-TTSHHHHHHH.....HTT..SEEEEEES-HHHHHHHHHHCCHHT-...........EEETTEECCCTS CS Methyltransf_11 2 dvGcGtGrlaeala.....krg..arvvgvDlspemlklakekaseegl...........vefvvadaeklp 55 d+Gc +G l++++ + +r +++Dl++ +l ake++ g+ vefv++d++k p tr|Q388Y3|Q388Y3_TRYB2 42 DAGCSSGGLLRHILtsqlqE-HsfSRALAIDLDKVALHEAKEAITALGFsspvallhpmhVEFVQGDLTKPP 112 99***999999988776643.158************************9*******************9943 PP == domain 2 score: 4.6 bits; conditional E-value: 0.1 T-EEEEEEES-CCC-C CS Methyltransf_11 59 nsfDlvvssevlhhve 74 +++D+v+s evl+h++ tr|Q388Y3|Q388Y3_TRYB2 145 HQYDAVISIEVLEHIN 160 599***********94 PP >> sp|Q582G4|ANM7_TRYB2 Protein arginine N-methyltransferase 7 OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.7 0.0 3.9e-06 0.00096 1 52 [. 100 155 .. 100 200 .. 0.85 Alignments for each domain: == domain 1 score: 18.7 bits; conditional E-value: 3.9e-06 EEET-TTSHHHHHHHHTT.SEEEEEES-HHHHHHHHHHCCHHT-...EEETTEECC CS Methyltransf_11 1 LdvGcGtGrlaealakrg.arvvgvDlspemlklakekaseegl...vefvvadae 52 L++G+G+G+l+ ak g + vv+v+ s+e+ kla+e+++ +++ v+++++ + sp|Q582G4|ANM7_TRYB2 100 LEIGAGSGLLSLMAAKLGaKWVVAVEGSEELAKLARENIRANNMehqVKVLHMMST 155 89****************999*******************9998866555555444 PP >> tr|Q38C62|Q38C62_TRYB2 Methyltransferase-like protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=18543 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.1 0.0 0.00011 0.027 2 95 .] 122 254 .. 121 254 .. 0.68 Alignments for each domain: == domain 1 score: 14.1 bits; conditional E-value: 0.00011 EET-TTSHHHHHHHHTT...SEEEEEES-HHHHHHHHHHCCHHT-......EEE............................TTEEC CS Methyltransf_11 2 dvGcGtGrlaealakrg...arvvgvDlspemlklakekaseegl......vef............................vvada 51 ++GcGtG+ + ++++++ +++g+D+s++++ + e+ +++ + + tr|Q38C62|Q38C62_TRYB2 122 ECGCGTGSTLLPIMNQFkdgVHFIGFDVSTAAVSALLEHPIASDFsaegrlT-VfpydlcygrvsasedcrrtkfktecgtlKTTLL 207 78************655566************95553333232223444431.2344556666666666677777776666555556 PP CCTSS-TT-EEEEEEES-CCC-...CCHHHHHHHHHHHEEEEEEEEE CS Methyltransf_11 52 eklpfpdnsfDlvvssevlhhv...edpekalkeiaRvLkpgGllvi 95 ek+p ++ +D+ ++ +vl + e + al ei+ +L ++G+l++ tr|Q38C62|Q38C62_TRYB2 208 EKVPGCSKGVDAAILVFVLSSLptiECMLYALTEIKSILHNDGILLF 254 67788888888888888888887766777888888888888888875 PP >> tr|Q38BY6|Q38BY6_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.0 0.0 6.6e-06 0.0016 1 52 [. 315 378 .. 315 386 .. 0.72 Alignments for each domain: == domain 1 score: 18.0 bits; conditional E-value: 6.6e-06 EEET-TTSHHHHHHHHTT.SEEEEEES-HHHHHHH....HHHCCHHT-.......EEETTEECC CS Methyltransf_11 1 LdvGcGtGrlaealakrg.arvvgvDlspemlkla....kekaseegl.......vefvvadae 52 Ld+Gc +G+++e l k g +v+gvD+sp+ l a +e+ +e++ v+fv++d+ tr|Q38BY6|Q38BY6_TRYB2 315 LDCGCHSGYMTELLLKAGaQEVLGVDVSPHHLGNAeatlSEHLRERRSssysrktVQFVRCDIL 378 8*******************************66622333333333334555667777777765 PP >> tr|Q57W60|Q57W60_TRYB2 S-adenosyl-methyltransferase mraW-like protein, putative OS=Trypanosoma brucei brucei (strain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.0 0.0 1.4e-05 0.0034 1 70 [. 131 207 .. 131 219 .. 0.83 Alignments for each domain: == domain 1 score: 17.0 bits; conditional E-value: 1.4e-05 EEET-TTSHHHHHHHHTT...SEEEEEES-HHHHHHHHHHCCHHT-..EEETTEECCC..TSS-TT-EEEEEEES-C CS Methyltransf_11 1 LdvGcGtGrlaealakrg...arvvgvDlspemlklakekaseegl..vefvvadaek..lpfpdnsfDlvvssevl 70 Ld+ G+G++a a+ ++g +rvv++D ++ ++ +a++ ++e g ++f ++ +++ f + sfD++++ + tr|Q57W60|Q57W60_TRYB2 131 LDCTLGSGYHAGAVLENGgpyTRVVALDCDHDAMHAARDLVEEFGGdrLRFYCCKMSEakAMFGERSFDAIMIDGGV 207 78889**********9999***************9999999887779999999999972246*********987655 PP >> tr|Q389Z0|Q389Z0_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.8 0.1 6.7e-05 0.016 1 44 [. 215 265 .. 215 312 .. 0.73 Alignments for each domain: == domain 1 score: 14.8 bits; conditional E-value: 6.7e-05 EEET-TTSHHHHHHHHTT..SEEEEEES-HHHHHHHHHHCCHHT-.....E CS Methyltransf_11 1 LdvGcGtGrlaealakrg..arvvgvDlspemlklakekaseegl.....v 44 Ld+ cGtG + a+ak++ a+v++vD+ +e++ +++e+a+ +gl + tr|Q389Z0|Q389Z0_TRYB2 215 LDMCCGTGCVGIAIAKHVpsAQVTAVDILDEAIGASEENAKLNGLeasrfC 265 8999***********999***************999999998886663331 PP >> tr|Q582P2|Q582P2_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.5 0.0 0.00017 0.041 1 32 [. 550 583 .. 550 674 .. 0.56 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 0.00017 EEET-TTSHHHHHHHHTTSEEEEEES-HHHH..H CS Methyltransf_11 1 LdvGcGtGrlaealakrgarvvgvDlspeml..k 32 Ld++cG+Gr+a +l+ + +vvg D+s+++l + tr|Q582P2|Q582P2_TRYB2 550 LDFACGAGRIAFELTSMFDQVVGSDFSARLLipA 583 89***************************99552 PP >> tr|Q383B4|Q383B4_TRYB2 tRNA (adenine(58)-N(1))-methyltransferase OS=Trypanosoma brucei brucei (strain 927/4 GUTat10. # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.3 0.0 0.014 3.5 2 44 .. 170 219 .. 169 247 .. 0.80 2 ? 4.4 0.0 0.12 28 69 94 .. 273 298 .. 257 299 .. 0.82 3 ? -0.8 0.0 4.9 1.2e+03 31 63 .. 374 406 .. 368 409 .. 0.76 Alignments for each domain: == domain 1 score: 7.3 bits; conditional E-value: 0.014 EET-TTSHHHHHHHHTT...SEEEEEES-HHHHHHHHHHCCHHT-....E CS Methyltransf_11 2 dvGcGtGrlaealakrg...arvvgvDlspemlklakekaseegl....v 44 ++G G+G+l+ la+++ + v++ D+ ++ a ++ +++gl v tr|Q383B4|Q383B4_TRYB2 170 EAGTGSGSLTHSLARTVapdGIVYTYDFHKKRCLEALQEFRRNGLpaslV 219 68************999999*********999977777777777654433 PP == domain 2 score: 4.4 bits; conditional E-value: 0.12 -CCC-CCHHHHHHHHHHHEEEEEEEE CS Methyltransf_11 69 vlhhvedpekalkeiaRvLkpgGllv 94 v+ v+ p a++++ vL+pgG+l+ tr|Q383B4|Q383B4_TRYB2 273 VFLDVPSPWLAIDNVLHVLRPGGMLC 298 44456889999************986 PP == domain 3 score: -0.8 bits; conditional E-value: 4.9 HHHHHHHCCHHT-EEETTEECCCTSS-TT-EEE CS Methyltransf_11 31 lklakekaseeglvefvvadaeklpfpdnsfDl 63 l++a+++ ++ ++v+ v+a+a ++ +++s D+ tr|Q383B4|Q383B4_TRYB2 374 LTFARRRLERIPVVDTVEASAAATNTASSSQDV 406 567788888877788888888888888888776 PP >> tr|Q57W77|Q57W77_TRYB2 Probable methyltransferase BMT2 homolog OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.6 0.0 4.3 1e+03 1 29 [. 320 353 .. 320 358 .. 0.78 2 ? 10.8 0.0 0.0012 0.29 32 95 .] 405 468 .. 396 468 .. 0.81 Alignments for each domain: == domain 1 score: -0.6 bits; conditional E-value: 4.3 EEET-TTSHHHHHHHHTT.....SEEEEEES-HH CS Methyltransf_11 1 LdvGcGtGrlaealakrg.....arvvgvDlspe 29 Ld+G++ G + + +g v+++Dlsp+ tr|Q57W77|Q57W77_TRYB2 320 LDIGSCYGPFGGRIVTNGvlqvpLAVTALDLSPY 353 7888888887777776666666789999999986 PP == domain 2 score: 10.8 bits; conditional E-value: 0.0012 HHHHHHCCHHT-EEETTEECCCT.SS-TT-EEEEEEES-CCC-...CCHHHHHHHHHHHEEEEEEEEE CS Methyltransf_11 32 klakekaseeglvefvvadaekl.pfpdnsfDlvvssevlhhv...edpekalkeiaRvLkpgGllvi 95 +++ e++ + + ++a+++ ++ + fD+v+ l ++ + +a+ ++ Lk gGllvi tr|Q57W77|Q57W77_TRYB2 405 RWCDEESGKYE----GTGSARRIlSLARGAFDVVFFCLLLSFLphpRLRYRACLHAYLALKDGGLLVI 468 55555555555....6788888559******************76567889999999********996 PP >> tr|Q385L0|Q385L0_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.0 0.00064 0.16 2 41 .. 181 222 .. 180 243 .. 0.77 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 0.00064 EET-TTSHHHHHHHHTT..SEEEEEES-HHHHHHHHHHCCHH CS Methyltransf_11 2 dvGcGtGrlaealakrg..arvvgvDlspemlklakekasee 41 d+GcGtGr+++ l ++ + +++ D ++ml + ++++++ tr|Q385L0|Q385L0_TRYB2 181 DFGCGTGRISCMLSRHSavGALYCYDSEAAMLGPCIDNVVRS 222 89************88788*******9999996666655555 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (95 nodes) Target sequences: 8561 (4332363 residues searched) Passed MSV filter: 335 (0.0391309); expected 171.2 (0.02) Passed bias filter: 319 (0.037262); expected 171.2 (0.02) Passed Vit filter: 68 (0.007943); expected 8.6 (0.001) Passed Fwd filter: 35 (0.00408831); expected 0.1 (1e-05) Initial search space (Z): 8561 [actual number of targets] Domain search space (domZ): 35 [number of targets reported over threshold] # CPU time: 0.10u 0.01s 00:00:00.11 Elapsed: 00:00:00.04 # Mc/sec: 10289.36 // [ok]