# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/Methyltransf_12.hmm.txt # target sequence database: proteomes/Drosophila_melanogaster.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: Methyltransf_12 [M=99] Accession: PF08242.11 Description: Methyltransferase domain Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.8e-18 66.7 0.0 4.3e-18 65.5 0.0 1.6 1 sp|Q9VJK8|JHAMT_DROME Juvenile hormone acid O-methyltr 3e-17 62.8 0.0 7.3e-17 61.6 0.0 1.7 1 sp|Q86BS6|METL_DROME Methyltransferase-like protein O 1e-16 61.1 0.0 1.9e-16 60.2 0.0 1.5 1 tr|Q9VIF3|Q9VIF3_DROME Ubiquinone biosynthesis O-methyl 2.4e-13 50.3 0.0 9.9e-13 48.3 0.0 2.0 2 tr|A1ZAY5|A1ZAY5_DROME Methyltransferase-like protein O 1.1e-11 45.0 0.2 1e-10 41.8 0.0 2.5 2 sp|Q9VNH1|BN3D2_DROME Probable RNA methyltransferase C 2.7e-11 43.7 0.0 4.8e-11 42.9 0.0 1.4 1 tr|Q9VG42|Q9VG42_DROME Glycine N-methyltransferase OS=D 1.9e-10 41.0 0.0 0.00012 22.4 0.0 3.0 2 sp|Q7K480|BN3D1_DROME Probable RNA methyltransferase b 2.3e-10 40.7 0.0 4.6e-10 39.7 0.0 1.5 1 tr|Q7K1S1|Q7K1S1_DROME LD45826p OS=Drosophila melanogas 1.4e-08 35.0 0.0 2.3e-08 34.3 0.0 1.4 1 tr|Q9VQJ8|Q9VQJ8_DROME Protein-lysine N-methyltransfera 2.6e-08 34.1 0.0 4.8e-08 33.3 0.0 1.4 1 sp|Q9VZD2|BN3D3_DROME Probable RNA methyltransferase C 1.1e-07 32.1 0.0 0.028 14.7 0.0 2.7 2 sp|Q9VIK9|MET13_DROME Methyltransferase-like protein 1 2.8e-07 30.8 0.0 7.3e-07 29.5 0.0 1.7 1 sp|Q9VYF8|COQ5_DROME 2-methoxy-6-polyprenyl-1,4-benzo 1.5e-06 28.5 0.1 4.5e-06 27.0 0.1 1.9 1 tr|Q9VQK8|Q9VQK8_DROME FI02048p OS=Drosophila melanogas 2.2e-06 27.9 0.0 1.1e-05 25.7 0.0 2.0 2 tr|Q9VMD3|Q9VMD3_DROME Uncharacterized protein, isoform 2.2e-06 27.9 0.0 6e-06 26.5 0.0 1.8 1 tr|Q9VFB3|Q9VFB3_DROME Arginine methyltransferase 3, is 1.2e-05 25.6 0.0 2.2e-05 24.7 0.0 1.4 1 sp|Q6NN40|NTM1_DROME Alpha N-terminal protein methylt 1.2e-05 25.6 0.0 2.2e-05 24.7 0.0 1.4 1 tr|A0A384ZCM4|A0A384ZCM4_DROME N-terminal methyltransferase, is 2.7e-05 24.4 0.0 0.0001 22.6 0.0 2.1 1 tr|Q9W1H1|Q9W1H1_DROME GH17155p OS=Drosophila melanogas 8.8e-05 22.8 2.0 0.00017 21.9 0.1 2.7 1 tr|Q9VBJ3|Q9VBJ3_DROME Fire dancer OS=Drosophila melano 9.6e-05 22.7 0.0 0.00025 21.3 0.0 1.7 1 tr|Q9VGW7|Q9VGW7_DROME Arginine methyltransferase 1 OS= 9.7e-05 22.7 0.0 0.00017 21.9 0.0 1.4 1 tr|Q9VFP8|Q9VFP8_DROME Arginine methyltransferase 6 OS= 0.00017 21.9 2.3 0.0002 21.6 0.1 2.4 1 tr|Q9W232|Q9W232_DROME Uncharacterized protein OS=Droso 0.0002 21.6 0.0 0.00081 19.7 0.0 2.0 1 tr|Q9VHW6|Q9VHW6_DROME RE22146p OS=Drosophila melanogas 0.00022 21.5 0.1 0.00063 20.1 0.0 1.9 1 tr|Q9VVV7|Q9VVV7_DROME Uncharacterized protein OS=Droso 0.00032 21.0 0.0 0.0011 19.3 0.0 2.0 1 sp|Q9VH48|CARM1_DROME Probable histone-arginine methyl 0.00041 20.7 0.0 0.0013 19.1 0.0 1.9 1 sp|Q9VJQ4|MCES_DROME mRNA cap guanine-N7 methyltransf 0.00075 19.8 0.0 0.0026 18.1 0.0 1.9 1 tr|Q9VQF8|Q9VQF8_DROME GH13185p2 OS=Drosophila melanoga 0.0021 18.4 0.0 0.0051 17.1 0.0 1.7 1 tr|Q9VBH7|Q9VBH7_DROME tRNA (adenine(58)-N(1))-methyltr 0.0026 18.1 0.0 0.0051 17.1 0.0 1.6 1 tr|Q9VQX9|Q9VQX9_DROME Arginine methyltransferase 2, is 0.0035 17.7 0.0 0.011 16.1 0.0 1.8 1 tr|Q9VL60|Q9VL60_DROME RE01590p OS=Drosophila melanogas 0.0041 17.5 0.1 0.0099 16.2 0.0 1.7 1 tr|Q8SX32|Q8SX32_DROME Arginine methyltransferase 8 OS= 0.0065 16.8 0.0 0.018 15.4 0.0 1.8 1 tr|A4V0X6|A4V0X6_DROME FI04554p OS=Drosophila melanogas 0.0066 16.8 0.0 0.011 16.0 0.0 1.3 1 tr|Q9VDC8|Q9VDC8_DROME FI06469p OS=Drosophila melanogas 0.0074 16.6 0.0 0.015 15.6 0.0 1.5 1 tr|Q8MSW4|Q8MSW4_DROME LD25448p2 OS=Drosophila melanoga ------ inclusion threshold ------ 0.019 15.3 0.0 0.062 13.7 0.0 1.9 1 sp|Q7K3B9|MET16_DROME U6 small nuclear RNA (adenine-(4 0.024 15.0 0.0 1.7 9.1 0.0 2.7 2 sp|Q27869|PIMT_DROME Protein-L-isoaspartate(D-asparta 0.039 14.3 0.0 0.35 11.2 0.0 2.5 1 tr|X2JGL7|X2JGL7_DROME Uncharacterized protein, isoform 0.043 14.2 0.0 0.093 13.1 0.0 1.6 1 sp|Q9VAQ5|DIM1_DROME Probable dimethyladenosine trans 0.087 13.2 0.0 0.25 11.7 0.0 2.0 1 sp|Q9I7X6|CARME_DROME Carnosine N-methyltransferase OS 0.13 12.6 0.8 0.91 9.9 0.0 2.8 2 tr|Q8SX24|Q8SX24_DROME RE67941p OS=Drosophila melanogas 0.25 11.7 1.6 1.2 9.6 1.6 2.3 1 tr|A1Z847|A1Z847_DROME Uncharacterized protein, isoform Domain annotation for each sequence (and alignments): >> sp|Q9VJK8|JHAMT_DROME Juvenile hormone acid O-methyltransferase OS=Drosophila melanogaster OX=7227 GN=jhamt PE=1 SV= # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 65.5 0.0 1.3e-20 4.3e-18 1 97 [. 40 137 .. 40 139 .. 0.98 Alignments for each domain: == domain 1 score: 65.5 bits; conditional E-value: 1.3e-20 Methyltransf_12 1 LeiGcGtGsllrallekl..pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhlkdireal 86 L++G+G+G++l+ + + l ++ +++g+Dis+++++ a+++ +++e+ +++ +++ ++ l ++ +g fD v+++ +lh++++++ al sp|Q9VJK8|JHAMT_DROME 40 LDVGSGSGNVLMDFVKPLlpIRGQLVGTDISSQMVHYASKHYQREERTRFQVLDIGCERLPEELSG-RFDHVTSFYCLHWVQNLKGAL 126 8*****************999***************************************999998.********************* PP Methyltransf_12 87 dniyklLkpgG 97 niy+lLkp+G sp|Q9VJK8|JHAMT_DROME 127 GNIYNLLKPEG 137 *********98 PP >> sp|Q86BS6|METL_DROME Methyltransferase-like protein OS=Drosophila melanogaster OX=7227 GN=metl PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 61.6 0.0 2.2e-19 7.3e-17 2 99 .] 138 240 .. 137 240 .. 0.83 Alignments for each domain: == domain 1 score: 61.6 bits; conditional E-value: 2.2e-19 Methyltransf_12 2 eiGcGtGsllrallekl..pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.....ssfDvvvasnvlhhl..kd 81 e+GcG+G+++ +ll++ p++++ g+D+s++aie + + ++ e +++++++ d+ ++ + +s D++v+++vl+++ k+ sp|Q86BS6|METL_DROME 138 ELGCGVGNTILPLLQYSsePQLKVFGCDFSARAIEILRSQRQFDE----KRCEVFVMDATLDHWQvpfeeNSQDIIVMIFVLSAIepKK 222 9*****************9***************55544444444....556666666554444566679******************* PP Methyltransf_12 82 irealdniyklLkpgGrl 99 ++++ldn+y+ L+pgG l sp|Q86BS6|METL_DROME 223 MQRVLDNCYRYLRPGGLL 240 ****************86 PP >> tr|Q9VIF3|Q9VIF3_DROME Ubiquinone biosynthesis O-methyltransferase, mitochondrial OS=Drosophila melanogaster OX=7227 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 60.2 0.0 5.8e-19 1.9e-16 1 98 [. 100 197 .. 100 198 .. 0.95 Alignments for each domain: == domain 1 score: 60.2 bits; conditional E-value: 5.8e-19 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg..ssfDvvvasnvlhhlkdirea 85 Le+GcG G l+++l++ ++++ g+D+ ++ ie+a+e+l+ +++ ++nv ++ + ++++++ + +D+v++s+vl+h+kd+ ++ tr|Q9VIF3|Q9VIF3_DROME 100 LEVGCGGGLLTEHLARL--GAQVAGIDLGEKLIEAAREHLKCSSPELASNVVYKIEPVDQHAKAncECYDAVIVSEVLEHVKDKVSL 184 8****************..**************************99999999988877666669********************** PP Methyltransf_12 86 ldniyklLkpgGr 98 l+ + LkpgG tr|Q9VIF3|Q9VIF3_DROME 185 LEASVRSLKPGGS 197 ************6 PP >> tr|A1ZAY5|A1ZAY5_DROME Methyltransferase-like protein OS=Drosophila melanogaster OX=7227 GN=CG4989 PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.0 9.2 3.1e+03 48 92 .. 31 74 .. 6 78 .. 0.46 2 ! 48.3 0.0 2.9e-15 9.9e-13 2 99 .] 88 197 .. 87 197 .. 0.84 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 9.2 Methyltransf_12 48 nnnvnlealdlldldggssfDvvvasnvlhhlkdirealdniykl 92 +++a++l+ +++ +D+ + n +kd++ + +++ +l tr|A1ZAY5|A1ZAY5_DROME 31 GLVPEYKANKLEIDAQ-RNWDIFYKRNETRFFKDRHWTTREFQEL 74 2333333333222222.3666655555555555555555555555 PP == domain 2 score: 48.3 bits; conditional E-value: 2.9e-15 Methyltransf_12 2 eiGcGtGsllrallekl.........pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.....ssfDvvvasn 74 e+GcG+G+l+++lle+ ++ ++++D+sp+a+ e +++ ++ +++ +++d+ ++ ss+D+ ++++ tr|A1ZAY5|A1ZAY5_DROME 88 EVGCGVGNLVFPLLEEQtseegcfsnSRFFFYACDFSPRAV----EFVRSNPLYDPSQISAFQCDITTQQVHdhippSSVDICTLIF 170 9***********************99999999*********....55555566666666666666555544455666********** PP Methyltransf_12 75 vlhhl..kdirealdniyklLkpgGrl 99 vl+++ ++ +++++n+ klLkpgG l tr|A1ZAY5|A1ZAY5_DROME 171 VLSAIhpQKFKDVVQNLGKLLKPGGLL 197 *****999999**************86 PP >> sp|Q9VNH1|BN3D2_DROME Probable RNA methyltransferase CG1239 OS=Drosophila melanogaster OX=7227 GN=CG1239 PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 41.8 0.0 3e-13 1e-10 1 99 [] 114 229 .. 114 229 .. 0.89 2 ? -0.5 0.0 4.8 1.6e+03 35 57 .. 240 262 .. 234 268 .. 0.84 Alignments for each domain: == domain 1 score: 41.8 bits; conditional E-value: 3e-13 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.............ssfDvvvasnv 75 L+iGc++G+l+ +++k++ +++g+Di++ i+da++ ++ +++ + + +++ +g+ +fDv+++++v sp|Q9VNH1|BN3D2_DROME 114 LDIGCNSGHLSIQIARKFEVKSLVGLDIDRGLINDAQKTVSHLKRHATPGQGIPHIQF--VHGNyvleddvlleierPQFDVILCLSV 199 8*************************************99999987766555555553..34445677778***************** PP Methyltransf_12 76 lhhl......kdirealdniyklLkpgGrl 99 ++ +++a++++y L+pgG+l sp|Q9VNH1|BN3D2_DROME 200 TKWIhlnfcdSGLKQAFRRMYLQLRPGGKL 229 ****************************97 PP == domain 2 score: -0.5 bits; conditional E-value: 4.8 Methyltransf_12 35 dakeklakrennnnnnvnleald 57 ++++kl++++++n n ++++ + sp|Q9VNH1|BN3D2_DROME 240 KRRKKLSEQIRDNYNAIKFRPDH 262 57899********9999998765 PP >> tr|Q9VG42|Q9VG42_DROME Glycine N-methyltransferase OS=Drosophila melanogaster OX=7227 GN=Gnmt PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 42.9 0.0 1.4e-13 4.8e-11 1 99 [] 65 176 .. 65 176 .. 0.88 Alignments for each domain: == domain 1 score: 42.9 bits; conditional E-value: 1.4e-13 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsai.edakeklakrennnnnnvnlealdlldldgg......ssfDvvvas.nvlhhl 79 L++ cGtG + +l e+ + e++ vD s +++ + ke+ a+r++ ++++ +e+ + l l + fD+v+++ n + hl tr|Q9VG42|Q9VG42_DROME 65 LDVACGTGVDSLMLVEE--GFEVVSVDASDKMLkYALKERWARRNEAAFDKWVIEEANWLTLYDDiqehiqDGFDAVICLgNSFAHL 149 8****************..**************545566667777777777777777777666669999****************** PP Methyltransf_12 80 .......kdirealdniyklLkpgGrl 99 ++ ++a+ n+ k+LkpgG+l tr|Q9VG42|Q9VG42_DROME 150 mdgfgdqREHKQAIGNFEKCLKPGGVL 176 *****999999**************97 PP >> sp|Q7K480|BN3D1_DROME Probable RNA methyltransferase bin3 OS=Drosophila melanogaster OX=7227 GN=bin3 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.4 0.0 3.5e-07 0.00012 1 41 [. 825 865 .. 825 880 .. 0.94 2 ! 15.2 0.0 5.9e-05 0.02 29 99 .] 968 1042 .. 960 1042 .. 0.91 Alignments for each domain: == domain 1 score: 22.4 bits; conditional E-value: 3.5e-07 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakekla 41 L+iGc++G+++ ++++l + +++g+Di+++ +++a++ l+ sp|Q7K480|BN3D1_DROME 825 LDIGCNVGHMTITVARHLAPKTIVGIDIDRELVARARRNLS 865 8********************************99998876 PP == domain 2 score: 15.2 bits; conditional E-value: 5.9e-05 Methyltransf_12 29 spsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhl......kdirealdniyklLkpgGrl 99 sp+++ k+++ ++ +++n+ l++++l +d + ++D++++++v ++ + ++ a++++ + L+pgG+l sp|Q7K480|BN3D1_DROME 968 SPNML-GNKNQFPANVFFRHTNYVLKDESLMASDTQ-QYDLILCLSVTKWIhlnfgdNGLKMAFKRMFNQLRPGGKL 1042 88899.899999999999999999999999998887.*******************99999**************97 PP >> tr|Q7K1S1|Q7K1S1_DROME LD45826p OS=Drosophila melanogaster OX=7227 GN=Dmel\CG8067 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 39.7 0.0 1.4e-12 4.6e-10 2 99 .] 79 169 .. 78 169 .. 0.86 Alignments for each domain: == domain 1 score: 39.7 bits; conditional E-value: 1.4e-12 Methyltransf_12 2 eiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhlkdirealdn 88 +iGc G l+r++l++ + ++t +D s+ ++ e+ + + + ++ ++++l+ +d s D+v++s lh+++d+ + + tr|Q7K1S1|Q7K1S1_DROME 79 DIGCSRGYLSRHILAE-SVEQLTLTDTSATML----EQAQGTPGLKMVKLVKDEEQLDFEDN--SLDLVISSLSLHWVNDLPGCFVR 158 8***************.777888*********....66666666666666666666665554..*********************** PP Methyltransf_12 89 iyklLkpgGrl 99 i++ Lkp+G++ tr|Q7K1S1|Q7K1S1_DROME 159 IKQSLKPDGVF 169 *********86 PP >> tr|Q9VQJ8|Q9VQJ8_DROME Protein-lysine N-methyltransferase CG9643 OS=Drosophila melanogaster OX=7227 GN=Dmel\CG9643 P # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 34.3 0.0 7e-11 2.3e-08 1 94 [. 64 162 .. 64 164 .. 0.76 Alignments for each domain: == domain 1 score: 34.3 bits; conditional E-value: 7e-11 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.ssfDvvvasnvlhhl....... 79 L++GcG+G +l l+++ + ++tgvD+sp+a+e a++ +++ +++++ dl + + + ++fDvv+ ++ ++ tr|Q9VQJ8|Q9VQJ8_DROME 64 LDLGCGNGMFLVGLANEGFTGDLTGVDYSPKAVELAQNIAEDNK----LSITYKVADLTQPQNElGQFDVVHDKGTYDAVslcpdna 146 8****************99**************33333333333....355666666554444467******999999999999888 PP Methyltransf_12 80 .kdirealdniyklLk 94 ++++ +ld + klL+ tr|Q9VQJ8|Q9VQJ8_DROME 147 kEKRALYLDTVEKLLR 162 5555578888888886 PP >> sp|Q9VZD2|BN3D3_DROME Probable RNA methyltransferase CG11342 OS=Drosophila melanogaster OX=7227 GN=CG11342 PE=3 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.3 0.0 1.4e-10 4.8e-08 1 91 [. 56 164 .. 56 170 .. 0.90 Alignments for each domain: == domain 1 score: 33.3 bits; conditional E-value: 1.4e-10 Methyltransf_12 1 LeiGcGtGsllrallekl.....pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.......ssfDvvvasnvl 76 L++Gc+ G l++ + ++l + ++++gvDi+p+ i++a+e+ + ++ + ++v++ + +++++ + ++fD++ + + sp|Q9VZD2|BN3D3_DROME 56 LDVGCNCGVLTQLMHKYLeerlhRSVKVLGVDIDPRLIQRASEENESPKDVSYACVDVLDDEAFESVKTymevnnlEKFDAICCYSIT 143 8************99999999999***********************************9999988877*************999998 PP Methyltransf_12 77 hhl......kdirealdniyk 91 ++ + +r++l+++ + sp|Q9VZD2|BN3D3_DROME 144 MWIhlnhhdQGLRFFLQKLSN 164 888887777777777776655 PP >> sp|Q9VIK9|MET13_DROME Methyltransferase-like protein 13 OS=Drosophila melanogaster OX=7227 GN=CG2614 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.6 0.0 9.7e-05 0.033 2 97 .. 54 154 .. 53 156 .. 0.76 2 ! 14.7 0.0 8.5e-05 0.028 2 60 .. 474 532 .. 473 549 .. 0.79 Alignments for each domain: == domain 1 score: 14.6 bits; conditional E-value: 9.7e-05 Methyltransf_12 2 eiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhl.........k 80 +GcG++ l++ + + ++t +Disp a+ ++ ++l+++++ ++++ +a+ + d+ sf v + ++l +l + sp|Q9VIK9|MET13_DROME 54 MLGCGNSKLSMDMYDT-GFRDITNIDISPIAV-KKMLELNAKSRPEMKFLQMDATAMTFPDE--SFSVSLDKGTLDALfaddepetrA 137 58***********999.99*************.77777777777777777777777766655..898888888888888887755545 PP Methyltransf_12 81 direaldniyklLkpgG 97 ++ ++++i + +++gG sp|Q9VIK9|MET13_DROME 138 VVENYFKEILRTMRNGG 154 55555556666666666 PP == domain 2 score: 14.7 bits; conditional E-value: 8.5e-05 Methyltransf_12 2 eiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlld 60 +G G G l + l ++lp++++t+v+i+p ++e a++ + +++++++ v + ld + sp|Q9VIK9|MET13_DROME 474 VVGLGGGGLCSFLHAALPQARITAVEIDPIMLEVAEQYFELKQDKRFHVVIDDGLDFVE 532 6899****************************999999988888877777666666554 PP >> sp|Q9VYF8|COQ5_DROME 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial OS=Drosophila melanogaster OX=7 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.5 0.0 2.2e-09 7.3e-07 1 99 [] 105 216 .. 105 216 .. 0.86 Alignments for each domain: == domain 1 score: 29.5 bits; conditional E-value: 2.2e-09 Methyltransf_12 1 LeiGcGtGsllrallekl........pdieytgvDispsai....edakeklakrennnnnnvnlealdlldldgg.ssfDvvvasnvl 76 L+ +GtG+++++ l++l +++++t++Di+++++ e+ak+ ++ +n v +++ d+++l+ + +sf + ++++ + sp|Q9VYF8|COQ5_DROME 105 LDMAGGTGDITFRYLRYLnnqpnpqqRPSHVTVSDINQHMLnvgeERAKRLGLTTDQLSNCTVAWQCADAEKLPFPdASFTAYTIAFGI 193 8999*********************99**************887545555555556667777778888877776669999999999999 PP Methyltransf_12 77 hhlkdirealdniyklLkpgGrl 99 ++ +++++l+++y++L pgGr+ sp|Q9VYF8|COQ5_DROME 194 RNCTHVDKVLSEAYRVLQPGGRF 216 9999*****************96 PP >> tr|Q9VQK8|Q9VQK8_DROME FI02048p OS=Drosophila melanogaster OX=7227 GN=Dmel\CG17219 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.0 0.1 1.3e-08 4.5e-06 1 99 [] 146 257 .. 146 257 .. 0.82 Alignments for each domain: == domain 1 score: 27.0 bits; conditional E-value: 1.3e-08 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg....................... 64 L++GcG G l + ++ ++++ + D++++++ +++ + n +nl++ +d++ + tr|Q9VQK8|Q9VQK8_DROME 146 LDLGCGCGLLGIYAMKH--GARVDFQDYNKDVL--------EYITYPNILLNLDDSLSEDEKLKfldnsttlysgdwshfaelsrdv 222 8****************..**************........44444444444444443333333556667777778999******** PP Methyltransf_12 65 ssfDvvvasnvlhhlkdirealdniyklLkpgGrl 99 +++D+++ s+++ ++++ +++ld ++ Lk +G++ tr|Q9VQK8|Q9VQK8_DROME 223 AKYDLILTSETIYNIANQQKLLDTFAGRLKSDGVI 257 *********************************86 PP >> tr|Q9VMD3|Q9VMD3_DROME Uncharacterized protein, isoform A OS=Drosophila melanogaster OX=7227 GN=HemK1 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.7 0.0 3.3e-08 1.1e-05 1 73 [. 150 226 .. 150 230 .. 0.95 2 ? -0.8 0.0 6.1 2e+03 85 99 .] 264 278 .. 242 278 .. 0.77 Alignments for each domain: == domain 1 score: 25.7 bits; conditional E-value: 3.3e-08 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg....ssfDvvvas 73 Le+GcG+G+++ +l +lp++ t+++ s++a a+e + + n +v++ + + ++ ++ +++D+++++ tr|Q9VMD3|Q9VMD3_DROME 150 LEVGCGSGAMSLSMLHSLPQVVATAIERSKAATVLAAENAKMLGLLNRFEVHNHTMEEDKYLPEalkdKKYDLIISN 226 8********************************************9999999999998888888**********975 PP == domain 2 score: -0.8 bits; conditional E-value: 6.1 Methyltransf_12 85 aldniyklLkpgGrl 99 ++d + ++L+pgG+l tr|Q9VMD3|Q9VMD3_DROME 264 VFDLACRHLRPGGKL 278 56666799*****87 PP >> tr|Q9VFB3|Q9VFB3_DROME Arginine methyltransferase 3, isoform A OS=Drosophila melanogaster OX=7227 GN=Art3 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.5 0.0 1.8e-08 6e-06 1 99 [] 248 345 .. 248 345 .. 0.77 Alignments for each domain: == domain 1 score: 26.5 bits; conditional E-value: 1.8e-08 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.ssfDvvv...asnvlhhlkdir 83 L++GcGtG l+ ++ ++++g+D s + a ++k n+++nv+l + l+d+d + ++D+++ + +l + ++ tr|Q9VFB3|Q9VFB3_DROME 248 LDVGCGTGILSIFASKA-GAARVVGIDNSDIVY-TAMDIIRK---NKVENVELIKGRLEDTDLPeTKYDIIIsewMGYFLLYESMLD 329 8*******999999888.99*************.55555555...555666666666666665557*****9777777777767777 PP Methyltransf_12 84 ealdniyklLkpgGrl 99 +++ ++L+p+G++ tr|Q9VFB3|Q9VFB3_DROME 330 SIIYARENHLNPNGII 345 8888888******975 PP >> sp|Q6NN40|NTM1_DROME Alpha N-terminal protein methyltransferase 1 OS=Drosophila melanogaster OX=7227 GN=Ntmt PE=1 SV # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 6.6e-08 2.2e-05 1 99 [] 111 210 .. 111 210 .. 0.85 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 6.6e-08 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhl..kdireald 87 L+ G+G G+++r ll + + + v+ +p++ ++a+e ++++ + + ++ + l + + +++D+v+ vl hl +d+ ++++ sp|Q6NN40|NTM1_DROME 111 LDCGAGIGRVTRNLLIP-RFSCVDLVEQDPAFADKAREYCTSEDGSRGKVGQIYNVGLQKFTPTQQYDLVWTQWVLGHLtdRDLVSFFR 198 899***********888.455555*********8888888888777777777777776666666***************999999**** PP Methyltransf_12 88 niyklLkpgGrl 99 +i++ L+pg+ l sp|Q6NN40|NTM1_DROME 199 RIKQGLAPGAFL 210 *********875 PP >> tr|A0A384ZCM4|A0A384ZCM4_DROME N-terminal methyltransferase, isoform B OS=Drosophila melanogaster OX=7227 GN=Ntmt PE # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 6.6e-08 2.2e-05 1 99 [] 111 210 .. 111 210 .. 0.85 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 6.6e-08 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhl 79 L+ G+G G+++r ll + + + v+ +p++ ++a+e ++++ + + ++ + l + + +++D+v+ vl hl tr|A0A384ZCM4|A0A384ZCM4_DROME 111 LDCGAGIGRVTRNLLIP-RFSCVDLVEQDPAFADKAREYCTSEDGSRGKVGQIYNVGLQKFTPTQQYDLVWTQWVLGHL 188 899***********888.455555*********8888888888777777777777776666666*************** PP Methyltransf_12 80 ..kdirealdniyklLkpgGrl 99 +d+ +++++i++ L+pg+ l tr|A0A384ZCM4|A0A384ZCM4_DROME 189 tdRDLVSFFRRIKQGLAPGAFL 210 999999*************875 PP >> tr|Q9W1H1|Q9W1H1_DROME GH17155p OS=Drosophila melanogaster OX=7227 GN=Dmel\CG5339 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.6 0.0 3.1e-07 0.0001 1 98 [. 130 219 .. 130 220 .. 0.75 Alignments for each domain: == domain 1 score: 22.6 bits; conditional E-value: 3.1e-07 Methyltransf_12 1 LeiGcGtGsllrallekl......pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhlkd 81 L+iG+G+G+++ ++++ ++++ +++ s + +l+k + n ++++ + +++++nvl + d tr|Q9W1H1|Q9W1H1_DROME 130 LDIGAGDGEISLRVANTVselsgsAGLRVFATEASWTMR----DRLKKLNFNVITEIDGLQ----------NLELILCLNVLDRCFD 202 8****************6666665566666666666666....444444433333333333..........6689************ PP Methyltransf_12 82 irealdniyklLkpgGr 98 ++l+ i+ +L+p+Gr tr|Q9W1H1|Q9W1H1_DROME 203 SFKLLEDIHLALAPNGR 219 ****************7 PP >> tr|Q9VBJ3|Q9VBJ3_DROME Fire dancer OS=Drosophila melanogaster OX=7227 GN=fid PE=4 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.9 0.1 4.9e-07 0.00017 2 99 .] 167 255 .. 166 255 .. 0.78 Alignments for each domain: == domain 1 score: 21.9 bits; conditional E-value: 4.9e-07 Methyltransf_12 2 eiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhl...kdirea 85 ++GcG+G++l + ++ i +gv+ + k a++++ ++ +++ +l d+ sfD+v+++ v+hh+ + + +a tr|Q9VBJ3|Q9VBJ3_DROME 167 DVGCGSGRYLTQCNPA---ICTIGVERCYRLS-----KVAHEKGGEVALCDNLELPFRDD----SFDAVLSLAVVHHFattERRVQA 241 89*****999999999...5555666555555.....66666666666666666665444....9*************9977777** PP Methyltransf_12 86 ldniyklLkpgGrl 99 l+++++ L+ gGr+ tr|Q9VBJ3|Q9VBJ3_DROME 242 LRELARILRIGGRV 255 ************85 PP >> tr|Q9VGW7|Q9VGW7_DROME Arginine methyltransferase 1 OS=Drosophila melanogaster OX=7227 GN=Art1 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.3 0.0 7.4e-07 0.00025 1 98 [. 96 195 .. 96 196 .. 0.81 Alignments for each domain: == domain 1 score: 21.3 bits; conditional E-value: 7.4e-07 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.ssfDvvv...asnvlhhlkdir 83 L++GcGtG l++ +++ +++++vD s ie a++ +++ +++ v +++ ++l+ g + +D+++ + +l + ++ tr|Q9VGW7|Q9VGW7_DROME 96 LDVGCGTGILSMFAAKA-GAAQVIAVDCSNI-IEFARQVVIDNNLQDVITVVKGKIEEIELPNGiEGVDIIIsewMGYCLFYESMLD 180 8*******999999999.999999****975.559999999999998877777777777777778****999665556666657777 PP Methyltransf_12 84 ealdniyklLkpgGr 98 +l k+Lk++G+ tr|Q9VGW7|Q9VGW7_DROME 181 TVLYARDKWLKKDGM 195 888888899999886 PP >> tr|Q9VFP8|Q9VFP8_DROME Arginine methyltransferase 6 OS=Drosophila melanogaster OX=7227 GN=Art6 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.9 0.0 4.9e-07 0.00017 1 99 [] 59 159 .. 59 159 .. 0.70 Alignments for each domain: == domain 1 score: 21.9 bits; conditional E-value: 4.9e-07 Methyltransf_12 1 LeiGcGtGsllrallekl....pdieytgvDispsaiedakeklakrenn.nnnnvnlealdlldldggssfDvvv...asnvlhhl 79 L++GcGtG l+ +e+ + +v+ a a+e +++++++ ++ v+ +++++ dg +++D++v + n+l tr|Q9VFP8|Q9VFP8_DROME 59 LDVGCGTGILSLFAAEAGaskvI-----AVECTDIAD-IAEEIIRDNQKEnVVKVVKGLVEQVELPDGIEKVDIIVsewMGNALYME 139 8*********9999999555444.....444444444.4444445444440455667777777666666*******77667777666 PP Methyltransf_12 80 kdirealdniyklLkpgGrl 99 + i+++l k+L+ gGr+ tr|Q9VFP8|Q9VFP8_DROME 140 AMINSVLFARDKWLTRGGRI 159 99999999999999999986 PP >> tr|Q9W232|Q9W232_DROME Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=CG17807 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.6 0.1 6.1e-07 0.0002 1 98 [. 400 487 .. 400 488 .. 0.76 Alignments for each domain: == domain 1 score: 21.6 bits; conditional E-value: 6.1e-07 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhl..kdir.e 84 L+iGcG+G +l+ +p + +g+D + + a + + ++ +++++ + +++ ss D +++ v+hhl k++r + tr|Q9W232|Q9W232_DROME 400 LDIGCGNGKYLS----CNPLLLSVGCDRAQGLL--AVGRRKGQNVFRCDCLVVPVRS-------SSIDGCISIAVIHHLatKERRlA 473 89******7664....34556789*********..3333334443455555555555.......39**************966666* PP Methyltransf_12 85 aldniyklLkpgGr 98 al++++++L+pgGr tr|Q9W232|Q9W232_DROME 474 ALQEMARVLRPGGR 487 *************7 PP >> tr|Q9VHW6|Q9VHW6_DROME RE22146p OS=Drosophila melanogaster OX=7227 GN=Dmel\CG10903 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.7 0.0 2.4e-06 0.00081 1 90 [. 56 137 .. 56 142 .. 0.67 Alignments for each domain: == domain 1 score: 19.7 bits; conditional E-value: 2.4e-06 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhlkdireald 87 L+iGcG+G ++l+++ + +g+Dis+s+++ a e+ + + + + + + ++++fD ++++++l++l + +++ + tr|Q9VHW6|Q9VHW6_DROME 56 LDIGCGSGLSGSVLEDS--EHMWIGIDISKSMLDIAVEREVAGD-----VILGDMGE-GMPFKPGTFDGAISISALQWLCNADKSYH 134 8*******999999999..88999*********66655544433.....22222222.22222258888888888888877766666 PP Methyltransf_12 88 niy 90 n + tr|Q9VHW6|Q9VHW6_DROME 135 NPH 137 655 PP >> tr|Q9VVV7|Q9VVV7_DROME Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=cg3808 PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 0.0 1.9e-06 0.00063 1 60 [. 420 477 .. 420 500 .. 0.87 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 1.9e-06 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlld 60 L+i cGtG+++ a++++ ++ gv+i p+ai+da+ +++ +n+++++ +a d ++ tr|Q9VVV7|Q9VVV7_DROME 420 LDICCGTGTITLAFAKH--CKKVMGVEIVPDAIKDAEFNAEANGIKNAKFFTGNADDFIK 477 89***************..*************************9999999999888765 PP >> sp|Q9VH48|CARM1_DROME Probable histone-arginine methyltransferase CARMER OS=Drosophila melanogaster OX=7227 GN=Art4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.3 0.0 3.3e-06 0.0011 1 98 [. 184 279 .. 184 280 .. 0.77 Alignments for each domain: == domain 1 score: 19.3 bits; conditional E-value: 3.3e-06 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvas..nvlhhlkdireal 86 L++G+G+G l++ ++ +++++++ s a +++l + + n +++ + ++++ + ++++Dv+++ + + + + + e+ sp|Q9VH48|CARM1_DROME 184 LDVGAGSGILSFFAVQA-GAAKVYAIEASNMAQ--YAQQLVESN-NVQHKISVIPGKIEEIELPEKVDVIISEpmGYMLYNERMLETY 267 8*************999.999999**9998887..555555544.35556666666666666668*****966334444449****** PP Methyltransf_12 87 dniyklLkpgGr 98 +++k+Lkp G+ sp|Q9VH48|CARM1_DROME 268 LHARKWLKPQGK 279 **********97 PP >> sp|Q9VJQ4|MCES_DROME mRNA cap guanine-N7 methyltransferase OS=Drosophila melanogaster OX=7227 GN=Rnmt PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.1 0.0 3.8e-06 0.0013 1 99 [] 140 255 .. 140 255 .. 0.80 Alignments for each domain: == domain 1 score: 19.1 bits; conditional E-value: 3.8e-06 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg................ssfDvvvas 73 L+ cG G l +++++ ++++++Di + ++e+ +++ +++ + + ++ ++ + + + + +v + sp|Q9VJQ4|MCES_DROME 140 LDMCCGKGGDLLKWEKA-AISHLICTDIAEVSVEQCQRRYQDILQ-RSEKSKFANKFTA-EFFAcdstlvrlrerykdpsLQLNLVSCQ 225 7899****999999999.888999*********777777776654.3344444443322.2222466699999*****9999******* PP Methyltransf_12 74 nvlhhl....kdirealdniyklLkpgGrl 99 +++h++ ++ + +++n++++LkpgG + sp|Q9VJQ4|MCES_DROME 226 FAFHYCfesmAQADCMMRNAAECLKPGGFF 255 *******99999999*************75 PP >> tr|Q9VQF8|Q9VQF8_DROME GH13185p2 OS=Drosophila melanogaster OX=7227 GN=HemK2 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.1 0.0 7.6e-06 0.0026 1 70 [. 47 113 .. 47 175 .. 0.78 Alignments for each domain: == domain 1 score: 18.1 bits; conditional E-value: 7.6e-06 Methyltransf_12 1 LeiGcGtGsllralleklpdieyt.gvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvv 70 +e+G+G+G ++ al++kl + +++ ++Di+p+a+ +a +++a r++ + + ++ d+l + s+Dv tr|Q9VQF8|Q9VQF8_DROME 47 VELGSGSGVIITALAKKLAGFSLClATDINPKAC-NATRRTATRNGARLDSIRCSLADAL---RPRSVDVL 113 69****************9999988*********.8888877777766555555555544...33355554 PP >> tr|Q9VBH7|Q9VBH7_DROME tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A OS=Drosophila melanogaste # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.1 0.0 1.5e-05 0.0051 2 70 .. 117 188 .. 116 192 .. 0.81 Alignments for each domain: == domain 1 score: 17.1 bits; conditional E-value: 1.5e-05 Methyltransf_12 2 eiGcGtGsllrallekl.pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg....ssfDvv 70 e G+G+Gsl++++l++l p+ +++ D++++ ++a+ ++++++ +++v++ ++d+ +l g ++ D+v tr|Q9VBH7|Q9VBH7_DROME 117 ESGTGSGSLSHYFLRALkPTGHLHTFDFHEARADQARDEFRRHGI--ADFVTVYHRDVCNLGFGaeldGKADAV 188 77***************99**************9**999999886..556766666766665555556666666 PP >> tr|Q9VQX9|Q9VQX9_DROME Arginine methyltransferase 2, isoform A OS=Drosophila melanogaster OX=7227 GN=Art2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.1 0.0 1.5e-05 0.0051 1 75 [. 72 145 .. 72 172 .. 0.71 Alignments for each domain: == domain 1 score: 17.1 bits; conditional E-value: 1.5e-05 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnn.vnlealdlldldggssfDvvvasnv 75 L++GcG G l++ +++ ++++v+ + + a++ +++e ++ + ++ +++d++ dg +++D++v+ tr|Q9VQX9|Q9VQX9_DROME 72 LDVGCGMGVLSMFAAKA-GSKRVLAVEAATISE-FAQQVVQDNEFGRVIQvIQGKVEDIELPDGIKKVDIIVCDWM 145 8***********99999.888899999988888.8999999988776655055555555555555*******8544 PP >> tr|Q9VL60|Q9VL60_DROME RE01590p OS=Drosophila melanogaster OX=7227 GN=anon-WO0118547.208 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.1 0.0 3.2e-05 0.011 2 90 .. 195 288 .. 194 292 .. 0.74 Alignments for each domain: == domain 1 score: 16.1 bits; conditional E-value: 3.2e-05 Methyltransf_12 2 eiGcGtGsllrallekl..pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhl...kdir 83 ++G+G G+ + + e + ey+ vD s+++ e ++ l++ ++n+ +++ + + + +D+v++s++l l ++++ tr|Q9VL60|Q9VL60_DROME 195 DFGSGIGTGMWVASELWreHIFEYYNVDRSREMNEISELILRDGHENKQIALRNVFYRQFLPAIETNYDLVIISHTLFELenkEQRE 281 899999966555555559899*************77777777766655555555555544444449********9999998877777 PP Methyltransf_12 84 ealdniy 90 ++l+n+ tr|Q9VL60|Q9VL60_DROME 282 DVLRNLW 288 9999876 PP >> tr|Q8SX32|Q8SX32_DROME Arginine methyltransferase 8 OS=Drosophila melanogaster OX=7227 GN=Art8 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.2 0.0 2.9e-05 0.0099 1 99 [] 45 146 .. 45 146 .. 0.84 Alignments for each domain: == domain 1 score: 16.2 bits; conditional E-value: 2.9e-05 Methyltransf_12 1 LeiGcGtGsllralleklpdieyt.gvDispsaiedakeklakrennnnnnvnlealdlldldgg.ssfDvvv...asnvlhhlkdi 82 +++G+GtG l++ ++++ +++++ +v+ s a + a + +++ n+ +v + + l+ + +++D++v + + l h + tr|Q8SX32|Q8SX32_DROME 45 MDVGAGTGILSAFCAKA--GARLVyAVEASNVATKVALDLIEDNGLTNVVKVIQSRVEEFVLPAEaEKVDIIVsewMGFYLLHEGML 129 69***************..999888*********99999999999877776666666655555558*******88877777777999 PP Methyltransf_12 83 realdniyklLkpgGrl 99 +++l k Lk gG l tr|Q8SX32|Q8SX32_DROME 130 DSVLLARDKFLKEGGLL 146 99999999999999976 PP >> tr|A4V0X6|A4V0X6_DROME FI04554p OS=Drosophila melanogaster OX=7227 GN=Dmel\CG10947 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.4 0.0 5.3e-05 0.018 1 97 [. 236 336 .. 236 338 .. 0.82 Alignments for each domain: == domain 1 score: 15.4 bits; conditional E-value: 5.3e-05 Methyltransf_12 1 LeiGcGtGsllrallekl.pdieytgvDispsaiedakeklakrennn...nnnvnlealdlldldggssfDvvvasnvlhhlkdir 83 Le+G+G sl+ +l+k + ++ +D ++ ++e+ ++ +e + ++ +++++ ++ +++++++fD ++++++l + + tr|A4V0X6|A4V0X6_DROME 236 LELGGGFTSLAGLMLAKYaTPYAVHLTDGNEISVENVRKTVCLNELSCytkCSVLKWQEKSARSQAEQAKFDFILCADCLFFDEARS 322 89****99999999998878999999999999999999988887766500055566677777777777************9977777 PP Methyltransf_12 84 ealdniyklLkpgG 97 +++d i L+p+G tr|A4V0X6|A4V0X6_DROME 323 ALVDTIWYYLAPEG 336 99999*99999999 PP >> tr|Q9VDC8|Q9VDC8_DROME FI06469p OS=Drosophila melanogaster OX=7227 GN=Dmel\CG3337 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.0 0.0 3.4e-05 0.011 1 84 [. 81 162 .. 81 170 .. 0.91 Alignments for each domain: == domain 1 score: 16.0 bits; conditional E-value: 3.4e-05 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhlkdir.e 84 L+iG+G+G+++ a +++ ++ gv+++p + +la+ ++ ++ +++ +dl + d + + vv+++v + ++d++ + tr|Q9VDC8|Q9VDC8_DROME 81 LDIGSGDGRIVVAAAQHCGALKADGVELNPWLV--YYSRLAALRHSVSKRTRFFRRDLWKFDIK-DYNFVVIFGVEQMMQDLEhK 162 8********************************..999999999999**********9887776.9*********9999988744 PP >> tr|Q8MSW4|Q8MSW4_DROME LD25448p2 OS=Drosophila melanogaster OX=7227 GN=CG42374-RA PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.6 0.0 4.5e-05 0.015 2 73 .. 57 127 .. 57 143 .. 0.94 Alignments for each domain: == domain 1 score: 15.6 bits; conditional E-value: 4.5e-05 Methyltransf_12 2 eiGcGtGsllralleklpdieyt.gvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvas 73 ++GcG G l+ a ++++t g +++ +a++ + + e n+++v+ ++l+l+ ++ ++sfD+v+++ tr|Q8MSW4|Q8MSW4_DROME 57 DLGCGCGMLSIASTLL--GAQLTvGFELDGDAVDTFRGNVVEMELPNVDCVRADVLQLIGSKWEKSFDTVLMN 127 89*****999888777..999999***********************************************97 PP >> sp|Q7K3B9|MET16_DROME U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase OS=Drosophila melanogaster OX=7227 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.7 0.0 0.00018 0.062 2 45 .. 110 153 .. 109 173 .. 0.88 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 0.00018 Methyltransf_12 2 eiGcGtGsllralleklpdieytgvDispsaiedakeklakren 45 +iGcG++ + + l +k +++ ++++ p+ ie ake ++++ sp|Q7K3B9|MET16_DROME 110 DIGCGSSCIYSLLGAKKNGWHMLALESKPQNIEYAKENVKRNHM 153 9***********************************99998875 PP >> sp|Q27869|PIMT_DROME Protein-L-isoaspartate(D-aspartate) O-methyltransferase OS=Drosophila melanogaster OX=7227 GN=P # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.9 0.0 0.41 1.4e+02 83 99 .] 66 82 .. 56 82 .. 0.82 2 ? 9.1 0.0 0.005 1.7 1 44 [. 83 132 .. 83 178 .. 0.74 Alignments for each domain: == domain 1 score: 2.9 bits; conditional E-value: 0.41 Methyltransf_12 83 realdniyklLkpgGrl 99 ++al+ ++++Lkpg+r+ sp|Q27869|PIMT_DROME 66 AFALEYLRDHLKPGARI 82 489***********985 PP == domain 2 score: 9.1 bits; conditional E-value: 0.005 Methyltransf_12 1 LeiGcGtGsllrallekl......pdieytgvDispsaiedakeklakre 44 L++G+G+G l++ + +++ d++++g++ +++ + + k+ l+ + sp|Q27869|PIMT_DROME 83 LDVGSGSGYLTACFYRYIkakgvdADTRIVGIEHQAELVRRSKANLNTDD 132 8**********999999666677777777777777777744444444333 PP >> tr|X2JGL7|X2JGL7_DROME Uncharacterized protein, isoform D OS=Drosophila melanogaster OX=7227 GN=Sms PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 0.0 0.001 0.35 3 97 .. 202 314 .. 201 316 .. 0.78 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 0.001 Methyltransf_12 3 iGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg..........ssfDvvv....asnv 75 +G+G+G+ll +ll++ + +++ ++i++ +++ + l+ ++++ ++ + ++ +++ d +fD+v+ + tr|X2JGL7|X2JGL7_DROME 202 LGGGDGALLYELLKE-NPKHVVMLEIDELVMQTCNKYLNVICGDVLEKRKGDQYEIIVGDCVeylkkfiaegRKFDYVFgdltDIPI 287 7**************.999************99999999999999999999999998777668999999999999998743332222 PP Methyltransf_12 76 lhhl........kdirealdniyklLkpgG 97 + + ir ++++ k+Lkp+G tr|X2JGL7|X2JGL7_DROME 288 ---TdapegetwDFIRTIFEHSFKVLKPDG 314 ...123344455667777777777777777 PP >> sp|Q9VAQ5|DIM1_DROME Probable dimethyladenosine transferase OS=Drosophila melanogaster OX=7227 GN=CG11837 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.1 0.0 0.00028 0.093 1 47 [. 54 98 .. 54 122 .. 0.80 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 0.00028 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennn 47 LeiG GtG+++ ++le+ ++++++i+++ + +++ ++ + sp|Q9VAQ5|DIM1_DROME 54 LEIGPGTGNMTVRMLER--AKKVIACEIDTRLAAELQKRVQATPLQP 98 8****************..**************77777777766655 PP >> sp|Q9I7X6|CARME_DROME Carnosine N-methyltransferase OS=Drosophila melanogaster OX=7227 GN=CG11596 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 0.0 0.00076 0.25 64 98 .. 256 307 .. 178 308 .. 0.79 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 0.00076 Methyltransf_12 64 g.................ssfDvvvasnvlhhlkdirealdniyklLkpgGr 98 + +++ v ++++ + +++ ++++ iyk L+pgG+ sp|Q9I7X6|CARME_DROME 256 KghfeiaagdflevyktpNAYNCVATCFFIDCANNVIDFIRTIYKILVPGGI 307 24444555555556667789*******************************6 PP >> tr|Q8SX24|Q8SX24_DROME RE67941p OS=Drosophila melanogaster OX=7227 GN=Dmel\CG18048 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.9 0.0 0.0027 0.91 2 79 .. 206 317 .. 205 329 .. 0.75 2 ? -1.4 0.0 9.1 3.1e+03 5 53 .. 351 396 .. 350 412 .. 0.65 Alignments for each domain: == domain 1 score: 9.9 bits; conditional E-value: 0.0027 Methyltransf_12 2 eiGcGtGsllrallekl.....pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg................... 64 e+G+G G+l+ l+ l ++++++ +D + ++ +kla re + + ++ +l+l+ l + tr|Q8SX24|Q8SX24_DROME 206 EFGAGKGQLAYFLATVLqeqklSHSQVVLIDRMSLRH-KKDNKLANREVVQRIRADIADLKLSAL--Pelkktqrtvafskhlcgaa 289 9********9999999999888899999998776666.555555555543333333333333333..24577888999999999999 PP Methyltransf_12 65 .............ssfDvvvasnvlhhl 79 +s D+v+++ ++hh tr|Q8SX24|Q8SX24_DROME 290 tdltlrcilgdgnASSDYVLIALCCHHR 317 9999999999999999***999999996 PP == domain 2 score: -1.4 bits; conditional E-value: 9.1 Methyltransf_12 5 cGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnl 53 cGtG l+r+ +++ + +++ ++ +++ + ++++ ++++++ +++ tr|Q8SX24|Q8SX24_DROME 351 CGTG-LSRERRKAMESADFQLTETNTQRL--TRQEREQIGQQCKRVLDY 396 7777.666666666778888888888888..555555555555554444 PP >> tr|A1Z847|A1Z847_DROME Uncharacterized protein, isoform B OS=Drosophila melanogaster OX=7227 GN=Dmel\CG2269 PE=1 SV= # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.6 1.6 0.0034 1.2 7 65 .. 451 512 .. 449 590 .. 0.77 Alignments for each domain: == domain 1 score: 9.6 bits; conditional E-value: 0.0034 Methyltransf_12 7 tGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg....s 65 +G+l+ + +++ ++y g+D ++++ ++ke l+kr++ + + +n e+ d +d+ + tr|A1Z847|A1Z847_DROME 451 VGHLMLRAKKSIDWSQYFGLDRKKKSL-QKKENLKKRSDTDSSTNNDEEDDEDDSSEAekkkR 512 678888888888889999*********.99999999998887777777666655555466773 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (99 nodes) Target sequences: 13786 (7394964 residues searched) Passed MSV filter: 699 (0.0507036); expected 275.7 (0.02) Passed bias filter: 627 (0.0454809); expected 275.7 (0.02) Passed Vit filter: 91 (0.0066009); expected 13.8 (0.001) Passed Fwd filter: 42 (0.00304657); expected 0.1 (1e-05) Initial search space (Z): 13786 [actual number of targets] Domain search space (domZ): 41 [number of targets reported over threshold] # CPU time: 0.17u 0.01s 00:00:00.18 Elapsed: 00:00:00.06 # Mc/sec: 12201.69 // [ok]