# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/Methyltransf_12.hmm.txt # target sequence database: proteomes/Homo_sapiens.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: Methyltransf_12 [M=99] Accession: PF08242.11 Description: Methyltransferase domain Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3e-18 68.6 0.1 5.7e-17 64.5 0.0 2.1 2 sp|Q8TCB7|METL6_HUMAN Methyltransferase-like protein 6 OS= 2.4e-15 59.3 0.1 5.3e-14 55.0 0.0 2.1 2 sp|Q8TCB7-2|METL6_HUMAN Isoform 2 of Methyltransferase-like 4.4e-15 58.4 0.0 1.4e-14 56.8 0.0 1.9 1 sp|Q6P1Q9|MET2B_HUMAN Methyltransferase-like protein 2B OS 4.6e-15 58.4 0.0 7.4e-15 57.7 0.0 1.3 1 sp|Q96IZ6-2|MET2A_HUMAN Isoform 2 of Methyltransferase-like 5.5e-15 58.1 0.0 1.9e-14 56.4 0.0 1.9 1 sp|Q96IZ6|MET2A_HUMAN Methyltransferase-like protein 2A OS 5.8e-15 58.0 0.0 9.9e-15 57.3 0.0 1.4 1 sp|Q6P1Q9-2|MET2B_HUMAN Isoform 2 of Methyltransferase-like 8.9e-14 54.2 0.0 1.4e-13 53.7 0.0 1.3 1 sp|Q6UX53|MET7B_HUMAN Methyltransferase-like protein 7B OS 1.1e-12 50.7 0.0 1.9e-12 50.0 0.0 1.4 1 sp|Q9NZJ6|COQ3_HUMAN Hexaprenyldihydroxybenzoate methyltr 2.1e-12 49.9 0.0 3.4e-12 49.2 0.0 1.3 1 tr|F8VQX6|F8VQX6_HUMAN Methyltransferase-like protein 7A (F 3.8e-12 49.0 0.0 7.1e-12 48.1 0.0 1.5 1 sp|Q9H8H3|MET7A_HUMAN Methyltransferase-like protein 7A OS 3.8e-12 49.0 0.0 7.1e-12 48.1 0.0 1.5 1 tr|H0YI09|H0YI09_HUMAN Methyltransferase-like protein 7A (F 5e-11 45.4 0.0 2.4e-10 43.3 0.0 2.1 1 tr|E7ETE0|E7ETE0_HUMAN Methyltransferase-like protein 8 OS= 1.4e-10 44.0 0.0 3.1e-10 42.9 0.0 1.6 1 tr|B3KR61|B3KR61_HUMAN HCG1811060, isoform CRA_c OS=Homo sa 2.5e-10 43.2 0.0 5.1e-10 42.2 0.0 1.5 1 sp|Q5TEU4|NDUF5_HUMAN NADH dehydrogenase [ubiquinone] 1 al 1.5e-09 40.7 0.1 3.9e-09 39.4 0.1 1.7 1 sp|Q9HBK9|AS3MT_HUMAN Arsenite methyltransferase OS=Homo s 5.4e-09 38.9 0.0 9.2e-09 38.2 0.0 1.4 1 sp|Q9BV86|NTM1A_HUMAN N-terminal Xaa-Pro-Lys N-methyltrans 6.3e-09 38.7 0.0 0.012 18.5 0.0 2.5 2 sp|Q7L2J0|MEPCE_HUMAN 7SK snRNA methylphosphate capping en 7.8e-09 38.4 0.1 4.9e-08 35.8 0.1 2.2 1 tr|F8VVX6|F8VVX6_HUMAN 2-methoxy-6-polyprenyl-1,4-benzoquin 7.9e-09 38.4 0.0 1.8e-08 37.2 0.0 1.7 1 sp|Q9P272|K1456_HUMAN Putative methyltransferase KIAA1456 1.1e-08 37.9 0.0 5.4e-08 35.7 0.0 2.0 1 tr|H7C2P8|H7C2P8_HUMAN Methyltransferase-like protein 8 (Fr 1.7e-08 37.3 0.0 2.8e-08 36.6 0.0 1.3 1 sp|Q14749|GNMT_HUMAN Glycine N-methyltransferase OS=Homo 1.8e-08 37.2 0.0 3.5e-08 36.3 0.0 1.4 1 tr|H7C3H9|H7C3H9_HUMAN Methyltransferase-like protein 6 (Fr 1.9e-08 37.2 0.1 1.4e-07 34.4 0.1 2.4 1 sp|Q5HYK3|COQ5_HUMAN 2-methoxy-6-polyprenyl-1,4-benzoquin 2.6e-08 36.7 0.0 3.6e-08 36.2 0.0 1.2 1 tr|H3BQD2|H3BQD2_HUMAN Methyltransferase-like protein 9 (Fr 3.1e-08 36.5 0.0 4.6e-08 35.9 0.0 1.3 1 tr|H3BM54|H3BM54_HUMAN Methyltransferase-like protein 9 (Fr 1.1e-07 34.6 0.0 1.8e-07 34.0 0.0 1.3 1 tr|H3BN86|H3BN86_HUMAN Methyltransferase-like protein 9 (Fr 1.8e-07 34.0 1.0 2.8e-06 30.2 1.0 2.1 1 tr|B4DDX3|B4DDX3_HUMAN Methyltransferase-like protein 6 OS= 1.9e-07 34.0 0.0 3.1e-07 33.3 0.0 1.4 1 sp|Q9H1A3-2|METL9_HUMAN Isoform 2 of Methyltransferase-like 1.9e-07 33.9 0.0 3.1e-07 33.2 0.0 1.4 1 sp|Q9H1A3|METL9_HUMAN Methyltransferase-like protein 9 OS= 2.1e-07 33.8 0.0 3.3e-07 33.2 0.0 1.3 1 sp|O60344-4|ECE2_HUMAN Isoform D of Endothelin-converting e 2.3e-07 33.7 0.0 4.3e-07 32.8 0.0 1.4 1 sp|P46597|ASMT_HUMAN Acetylserotonin O-methyltransferase 2.8e-07 33.4 0.0 8.4e-07 31.9 0.0 1.9 1 sp|P49327|FAS_HUMAN Fatty acid synthase OS=Homo sapiens 6.1e-07 32.3 0.0 1.3e-06 31.3 0.0 1.6 1 sp|P50135|HNMT_HUMAN Histamine N-methyltransferase OS=Hom 8.8e-07 31.8 0.0 0.00093 22.1 0.0 3.4 2 sp|Q8N6R0-1|MET13_HUMAN Isoform 4 of Methyltransferase-like 1.3e-06 31.3 0.1 0.001 22.0 0.0 3.4 2 sp|Q8N6R0-4|MET13_HUMAN Isoform 2 of Methyltransferase-like 1.7e-06 30.9 0.0 0.0011 21.8 0.0 3.3 2 sp|Q8N6R0|MET13_HUMAN Methyltransferase-like protein 13 OS 1.7e-06 30.9 0.0 0.0011 21.8 0.0 3.3 2 tr|B4E2X3|B4E2X3_HUMAN Methyltransferase-like protein 13 OS 1.8e-06 30.8 0.0 2.7e-06 30.2 0.0 1.3 1 tr|H3BQF6|H3BQF6_HUMAN Uncharacterized protein (Fragment) O 2.8e-06 30.2 0.1 4.4e-06 29.6 0.1 1.2 1 tr|H7C1L4|H7C1L4_HUMAN Methyltransferase-like protein 6 (Fr 3.8e-06 29.8 0.0 6.5e-06 29.0 0.0 1.4 1 sp|Q5JPI9|MET10_HUMAN Methyltransferase-like protein 10 OS 4.3e-06 29.6 0.0 5e-06 29.4 0.0 1.1 1 tr|H7C2C8|H7C2C8_HUMAN Methyltransferase-like protein 2B (F 1.2e-05 28.1 0.1 8.2e-05 25.5 0.0 2.2 1 sp|Q9H825-2|METL8_HUMAN Isoform 2 of Methyltransferase-like 1.4e-05 27.9 0.0 2.7e-05 27.0 0.0 1.5 1 tr|K7EP06|K7EP06_HUMAN mRNA cap guanine-N7 methyltransferas 1.9e-05 27.5 0.0 3.3e-05 26.7 0.0 1.4 1 tr|S4R338|S4R338_HUMAN N-terminal Xaa-Pro-Lys N-methyltrans 2.2e-05 27.3 0.0 0.00012 24.9 0.0 2.1 1 sp|Q9H825|METL8_HUMAN Methyltransferase-like protein 8 OS= 2.8e-05 27.0 0.0 6.8e-05 25.8 0.0 1.7 1 sp|O43148|MCES_HUMAN mRNA cap guanine-N7 methyltransferas 3e-05 26.9 0.0 6.2e-05 25.9 0.0 1.4 1 sp|P46597-3|ASMT_HUMAN Isoform 3 of Acetylserotonin O-methy 3.2e-05 26.8 0.0 7.5e-05 25.6 0.0 1.7 1 sp|O43148-2|MCES_HUMAN Isoform 2 of mRNA cap guanine-N7 met 3.5e-05 26.7 0.0 6.4e-05 25.8 0.0 1.4 1 tr|H7C552|H7C552_HUMAN Methyltransferase-like protein 2B (F 4e-05 26.5 1.0 0.001 22.0 1.0 2.1 1 tr|M0R0W0|M0R0W0_HUMAN Methyltransferase-like protein 6 (Fr 6.4e-05 25.8 0.0 0.00012 25.0 0.0 1.4 1 sp|Q5VVY1|NTM1B_HUMAN Alpha N-terminal protein methyltrans 6.6e-05 25.8 0.0 0.0002 24.2 0.0 1.9 1 sp|Q96BT7|ALKB8_HUMAN Alkylated DNA repair protein alkB ho 6.7e-05 25.8 0.0 0.0002 24.2 0.0 1.9 1 sp|Q96BT7-4|ALKB8_HUMAN Isoform 4 of Alkylated DNA repair pr 0.00012 25.0 0.0 0.0002 24.2 0.0 1.4 1 tr|H7C4Z8|H7C4Z8_HUMAN Methyltransferase-like protein 2B (F 0.00014 24.7 0.0 0.00023 24.1 0.0 1.4 1 sp|Q8N6F8|WBS27_HUMAN Williams-Beuren syndrome chromosomal 0.00015 24.7 0.0 0.004 20.1 0.0 2.2 2 sp|Q7L2J0-2|MEPCE_HUMAN Isoform 2 of 7SK snRNA methylphospha 0.00015 24.6 0.0 0.00026 23.9 0.0 1.4 1 sp|Q9Y5R4|HEMK1_HUMAN HemK methyltransferase family member 0.00021 24.2 0.0 0.00033 23.5 0.0 1.4 1 tr|H7C258|H7C258_HUMAN HemK methyltransferase family member 0.00034 23.5 0.1 0.00073 22.4 0.1 1.5 1 tr|F8WD67|F8WD67_HUMAN Uncharacterized methyltransferase WB 0.00047 23.1 0.0 0.00092 22.1 0.0 1.6 1 sp|O43709-2|WBS22_HUMAN Isoform 2 of Uncharacterized methylt 0.00048 23.0 0.0 0.0009 22.2 0.0 1.4 1 tr|E7EMN2|E7EMN2_HUMAN Methyltransferase-like protein 5 OS= 0.00068 22.5 0.0 0.0014 21.6 0.0 1.5 1 tr|B8ZZE3|B8ZZE3_HUMAN Methyltransferase like 5, isoform CR 0.00069 22.5 0.0 0.0015 21.5 0.0 1.6 1 sp|O43709|WBS22_HUMAN Uncharacterized methyltransferase WB 0.00074 22.4 0.0 0.0015 21.4 0.0 1.5 1 sp|Q9NRN9|METL5_HUMAN Methyltransferase-like protein 5 OS= 0.00078 22.3 0.0 0.0016 21.3 0.0 1.6 1 tr|C9K060|C9K060_HUMAN Uncharacterized methyltransferase WB 0.001 22.0 0.0 0.0021 21.0 0.0 1.5 1 tr|B8ZZC8|B8ZZC8_HUMAN Methyltransferase-like protein 5 OS= 0.0012 21.7 0.0 0.0032 20.4 0.0 1.7 1 sp|O60344|ECE2_HUMAN Endothelin-converting enzyme 2 OS=Ho 0.0014 21.6 0.1 0.0036 20.2 0.2 1.6 1 tr|F8WD87|F8WD87_HUMAN Uncharacterized methyltransferase WB 0.0014 21.5 0.2 0.0066 19.4 0.0 2.2 1 sp|Q9BTF0|THUM2_HUMAN THUMP domain-containing protein 2 OS 0.0017 21.3 0.1 0.0038 20.1 0.1 1.5 1 tr|E9PCQ7|E9PCQ7_HUMAN Uncharacterized methyltransferase WB 0.0021 21.0 0.1 0.0053 19.7 0.2 1.6 1 tr|B3KR83|B3KR83_HUMAN Uncharacterized methyltransferase WB 0.0023 20.8 0.1 0.0099 18.8 0.0 2.1 1 sp|O60678-2|ANM3_HUMAN Isoform 2 of Protein arginine N-meth 0.0028 20.5 0.1 0.012 18.5 0.0 2.1 1 sp|O60678|ANM3_HUMAN Protein arginine N-methyltransferase 0.0029 20.5 0.0 0.0092 18.9 0.0 1.8 1 sp|A8MUP2|MET12_HUMAN Methyltransferase-like protein 12, m 0.0041 20.0 0.0 0.006 19.5 0.0 1.2 1 tr|D6RCL3|D6RCL3_HUMAN Probable dimethyladenosine transfera 0.0045 19.9 0.0 0.016 18.2 0.0 1.8 1 tr|B4DP72|B4DP72_HUMAN 2-methoxy-6-polyprenyl-1,4-benzoquin 0.0047 19.9 0.0 0.048 16.6 0.0 2.5 1 sp|Q9H7H0-3|MET17_HUMAN Isoform 3 of Methyltransferase-like 0.0068 19.3 0.0 2.3 11.2 0.0 2.5 2 sp|Q5TEU4-2|NDUF5_HUMAN Isoform 2 of NADH dehydrogenase [ubi 0.0072 19.3 0.0 0.021 17.8 0.0 1.8 1 sp|Q5T8I9|HENMT_HUMAN Small RNA 2'-O-methyltransferase OS= ------ inclusion threshold ------ 0.011 18.7 0.0 0.11 15.5 0.0 2.2 2 sp|Q7Z5W3|BN3D2_HUMAN Pre-miRNA 5'-monophosphate methyltra 0.012 18.5 0.0 0.026 17.5 0.0 1.5 1 sp|Q9UNQ2|DIM1_HUMAN Probable dimethyladenosine transfera 0.012 18.5 0.0 0.03 17.3 0.0 1.7 1 tr|K7EQA8|K7EQA8_HUMAN Histone-arginine methyltransferase C 0.013 18.5 0.0 0.043 16.8 0.0 1.9 1 sp|Q9H7H0-2|MET17_HUMAN Isoform 2 of Methyltransferase-like 0.013 18.4 0.0 0.044 16.7 0.0 1.9 1 sp|Q9H7H0|MET17_HUMAN Methyltransferase-like protein 17, m 0.015 18.3 0.0 0.063 16.2 0.0 2.0 1 tr|F8W9F3|F8W9F3_HUMAN Protein-L-isoaspartate O-methyltrans 0.015 18.2 0.0 0.041 16.8 0.0 1.8 1 sp|O95568|MET18_HUMAN Histidine protein methyltransferase 0.015 18.2 0.0 0.037 17.0 0.0 1.7 1 sp|Q86X55-2|CARM1_HUMAN Isoform 2 of Histone-arginine methyl 0.016 18.2 0.0 0.3 14.0 0.0 2.3 1 sp|P40261|NNMT_HUMAN Nicotinamide N-methyltransferase OS= 0.02 17.8 0.0 0.074 16.0 0.0 2.0 1 sp|Q86X55-1|CARM1_HUMAN Isoform 1 of Histone-arginine methyl 0.022 17.7 0.0 0.09 15.7 0.0 2.0 1 sp|Q9NV79-2|PCMD2_HUMAN Isoform 2 of Protein-L-isoaspartate 0.022 17.7 0.0 0.078 15.9 0.0 2.0 1 sp|Q86X55|CARM1_HUMAN Histone-arginine methyltransferase C 0.026 17.4 0.0 0.1 15.6 0.0 2.0 1 sp|Q9NV79|PCMD2_HUMAN Protein-L-isoaspartate O-methyltrans 0.028 17.3 0.0 0.048 16.6 0.0 1.4 1 sp|Q9Y5N5|HEMK2_HUMAN HemK methyltransferase family member 0.03 17.3 2.9 0.47 13.4 0.0 3.1 1 sp|O43159|RRP8_HUMAN Ribosomal RNA-processing protein 8 O 0.033 17.1 0.0 0.061 16.3 0.0 1.5 1 sp|Q96GJ1-3|TRM2_HUMAN Isoform 3 of tRNA (uracil(54)-C(5))- 0.037 17.0 0.0 0.069 16.1 0.0 1.4 1 tr|F2Z384|F2Z384_HUMAN tRNA (uracil(54)-C(5))-methyltransfe 0.037 17.0 0.0 0.069 16.1 0.0 1.4 1 sp|Q96GJ1-2|TRM2_HUMAN Isoform 2 of tRNA (uracil(54)-C(5))- 0.039 16.9 0.0 0.071 16.1 0.0 1.4 1 sp|Q96GJ1|TRM2_HUMAN tRNA (uracil(54)-C(5))-methyltransfe 0.042 16.8 0.0 0.076 16.0 0.0 1.4 1 sp|Q9Y5N5-2|HEMK2_HUMAN Isoform 2 of HemK methyltransferase 0.046 16.7 0.0 0.14 15.2 0.0 1.9 1 sp|O95671-3|ASML_HUMAN Isoform 3 of N-acetylserotonin O-met 0.047 16.6 0.0 0.13 15.2 0.0 1.8 1 tr|E7ER97|E7ER97_HUMAN N-acetylserotonin O-methyltransferas 0.047 16.6 0.0 0.13 15.3 0.0 1.7 1 tr|E9PPP6|E9PPP6_HUMAN Ribosomal RNA-processing protein 8 O 0.053 16.5 0.0 0.074 16.0 0.0 1.2 1 tr|E9PNR9|E9PNR9_HUMAN Protein arginine N-methyltransferase 0.054 16.5 0.0 0.16 14.9 0.0 1.8 1 sp|O95671|ASML_HUMAN N-acetylserotonin O-methyltransferas 0.055 16.4 0.0 0.1 15.6 0.0 1.5 1 sp|Q9NR22-2|ANM8_HUMAN Isoform 2 of Protein arginine N-meth 0.055 16.4 0.0 0.15 15.0 0.0 1.8 1 sp|O95671-2|ASML_HUMAN Isoform 2 of N-acetylserotonin O-met 0.056 16.4 0.0 0.1 15.5 0.0 1.5 1 sp|Q9NR22|ANM8_HUMAN Protein arginine N-methyltransferase 0.07 16.1 0.0 0.091 15.7 0.0 1.2 1 tr|H3BNT3|H3BNT3_HUMAN UPF0585 protein C16orf13 (Fragment) 0.073 16.0 0.0 0.12 15.3 0.0 1.4 1 tr|H0Y2Q1|H0Y2Q1_HUMAN tRNA (adenine(58)-N(1))-methyltransf 0.076 16.0 0.1 0.65 13.0 0.1 2.3 1 tr|F8VP53|F8VP53_HUMAN 2-methoxy-6-polyprenyl-1,4-benzoquin 0.079 15.9 0.0 0.1 15.5 0.0 1.2 1 tr|H3BPE9|H3BPE9_HUMAN Methyltransferase-like protein 9 (Fr 0.08 15.9 0.1 0.26 14.2 0.1 1.9 1 sp|Q7Z624|CMKMT_HUMAN Calmodulin-lysine N-methyltransferas 0.084 15.8 0.0 0.12 15.4 0.0 1.2 1 tr|H3BMF3|H3BMF3_HUMAN UPF0585 protein C16orf13 (Fragment) 0.087 15.8 0.0 0.15 15.0 0.0 1.4 1 sp|Q96LA8|ANM6_HUMAN Protein arginine N-methyltransferase 0.09 15.7 0.0 0.14 15.1 0.0 1.3 1 tr|E9PQ98|E9PQ98_HUMAN Protein arginine N-methyltransferase 0.095 15.7 0.0 0.15 15.0 0.0 1.3 1 tr|E9PIX6|E9PIX6_HUMAN Protein arginine N-methyltransferase 0.1 15.6 0.0 0.17 14.8 0.0 1.3 1 sp|Q9BV86-2|NTM1A_HUMAN Isoform 2 of N-terminal Xaa-Pro-Lys 0.11 15.5 0.0 0.27 14.2 0.0 1.7 1 sp|Q8IZ69-2|TRM2A_HUMAN Isoform 2 of tRNA (uracil-5-)-methyl 0.11 15.5 0.0 0.17 14.8 0.0 1.4 1 sp|Q96S19|CP013_HUMAN UPF0585 protein C16orf13 OS=Homo sap 0.11 15.4 0.0 0.17 14.8 0.0 1.3 1 sp|Q96S19-4|CP013_HUMAN Isoform 4 of UPF0585 protein C16orf1 0.11 15.4 0.0 0.2 14.6 0.0 1.5 1 sp|Q96FX7|TRM61_HUMAN tRNA (adenine(58)-N(1))-methyltransf 0.12 15.4 0.0 1.7e+02 5.3 0.0 3.9 2 tr|E9PHY1|E9PHY1_HUMAN Low-density lipoprotein receptor-rel 0.12 15.3 0.0 0.21 14.6 0.0 1.4 1 tr|H0YDE4|H0YDE4_HUMAN Protein arginine N-methyltransferase 0.12 15.3 0.0 0.19 14.7 0.0 1.3 1 tr|A8MT87|A8MT87_HUMAN Phenylethanolamine N-methyltransfera 0.12 15.3 0.0 0.32 14.0 0.0 1.7 1 sp|Q8IZ69|TRM2A_HUMAN tRNA (uracil-5-)-methyltransferase h 0.14 15.1 0.0 0.52 13.3 0.0 2.1 1 sp|Q8N4J0|CI041_HUMAN UPF0586 protein C9orf41 OS=Homo sapi 0.16 14.9 0.0 0.64 13.0 0.0 1.9 1 tr|K7ES84|K7ES84_HUMAN Protein FAM86A OS=Homo sapiens GN=FA 0.16 14.9 0.0 0.51 13.3 0.0 1.8 1 sp|Q8N7N1|F86B1_HUMAN Protein FAM86B1 OS=Homo sapiens GN=F 0.17 14.9 0.0 0.58 13.1 0.0 1.9 1 tr|F8VZA8|F8VZA8_HUMAN Methyltransferase-like protein 25 (F 0.18 14.8 0.0 0.42 13.6 0.0 1.6 1 sp|P11086|PNMT_HUMAN Phenylethanolamine N-methyltransfera 0.19 14.7 0.0 0.63 13.0 0.0 1.9 1 tr|E9PN63|E9PN63_HUMAN Protein FAM86B1 OS=Homo sapiens GN=F 0.21 14.6 0.0 0.78 12.7 0.0 1.9 1 sp|Q96G04-2|FA86A_HUMAN Isoform 2 of Protein FAM86A OS=Homo 0.21 14.5 0.0 0.67 12.9 0.0 1.8 1 tr|H0YIW7|H0YIW7_HUMAN Methyltransferase-like protein 25 (F 0.22 14.5 0.0 0.44 13.5 0.0 1.6 1 sp|Q99873-3|ANM1_HUMAN Isoform 3 of Protein arginine N-meth 0.22 14.5 0.0 0.4 13.7 0.0 1.5 1 tr|E9PKG1|E9PKG1_HUMAN Protein arginine N-methyltransferase 0.23 14.4 0.0 0.47 13.4 0.0 1.6 1 sp|Q99873-4|ANM1_HUMAN Isoform 4 of Protein arginine N-meth 0.23 14.4 0.0 0.45 13.5 0.0 1.5 1 sp|Q99873-2|ANM1_HUMAN Isoform 2 of Protein arginine N-meth 0.24 14.3 0.0 0.42 13.6 0.0 1.3 1 tr|B7U631|B7U631_HUMAN PRMT2 beta variant OS=Homo sapiens G 0.26 14.3 0.0 0.49 13.4 0.0 1.5 1 sp|Q99873|ANM1_HUMAN Protein arginine N-methyltransferase 0.26 14.3 0.0 0.98 12.4 0.0 1.9 1 sp|Q96G04|FA86A_HUMAN Protein FAM86A OS=Homo sapiens GN=FA 0.26 14.2 0.0 2e+02 5.0 0.0 3.4 2 sp|Q8N6R0-3|MET13_HUMAN Isoform 3 of Methyltransferase-like 0.27 14.2 0.0 0.51 13.3 0.0 1.5 1 tr|H7C2I1|H7C2I1_HUMAN Protein arginine N-methyltransferase 0.27 14.2 0.0 0.35 13.8 0.0 1.3 1 tr|H3BQ23|H3BQ23_HUMAN Anamorsin (Fragment) OS=Homo sapiens 0.28 14.2 0.0 0.44 13.5 0.0 1.4 1 tr|B7U630|B7U630_HUMAN PRMT2 alpha variant OS=Homo sapiens 0.28 14.2 0.0 0.69 12.9 0.0 1.7 1 sp|Q96MG8|PCMD1_HUMAN Protein-L-isoaspartate O-methyltrans 0.34 13.9 0.0 1.1 12.2 0.0 1.8 1 tr|E9PQV7|E9PQV7_HUMAN Protein FAM86B2 (Fragment) OS=Homo s 0.35 13.9 0.0 1.1 12.2 0.0 1.8 1 tr|H7BXI9|H7BXI9_HUMAN Protein FAM86B2 OS=Homo sapiens GN=F 0.35 13.8 0.1 6.2 9.8 0.1 2.2 2 tr|B1ANH5|B1ANH5_HUMAN Guanylate kinase OS=Homo sapiens GN= 0.36 13.8 0.1 1.6 11.8 0.1 2.2 1 sp|Q8N6Q8|MET25_HUMAN Methyltransferase-like protein 25 OS 0.4 13.6 0.1 1.2 12.1 0.0 1.8 1 tr|G3V353|G3V353_HUMAN Methyltransferase-like protein 17, m 0.4 13.6 0.0 1.4 11.9 0.0 1.9 1 sp|P0C5J1|F86B2_HUMAN Protein FAM86B2 OS=Homo sapiens GN=F 0.43 13.6 0.0 1.1 12.2 0.0 1.8 1 sp|A6NDL7|MT21E_HUMAN Putative methyltransferase-like prot 0.44 13.5 0.1 1.4 11.9 0.1 1.9 1 sp|Q5VZV1|MT21C_HUMAN Protein-lysine methyltransferase MET 0.46 13.5 0.0 0.7 12.9 0.0 1.3 1 tr|H7C2H9|H7C2H9_HUMAN Protein arginine N-methyltransferase 0.47 13.4 0.0 3.4 10.7 0.0 2.1 2 tr|B1ANH6|B1ANH6_HUMAN Guanylate kinase OS=Homo sapiens GN= 0.48 13.4 0.0 0.93 12.5 0.0 1.5 1 sp|P55345|ANM2_HUMAN Protein arginine N-methyltransferase 0.57 13.1 0.0 0.92 12.5 0.0 1.4 1 tr|H3BUG4|H3BUG4_HUMAN Anamorsin OS=Homo sapiens GN=CIAPIN1 0.64 13.0 0.1 5.9 9.9 0.0 2.2 2 sp|Q16774|KGUA_HUMAN Guanylate kinase OS=Homo sapiens GN= 0.65 13.0 0.0 4.2 10.4 0.0 2.2 1 tr|B3KU92|B3KU92_HUMAN Putative protein arginine N-methyltr 0.71 12.8 0.0 1.2 12.2 0.0 1.3 1 tr|B7U632|B7U632_HUMAN PRMT2 gamma variant OS=Homo sapiens 0.73 12.8 0.0 1.4 11.9 0.0 1.5 1 tr|H3BSS9|H3BSS9_HUMAN Protein arginine N-methyltransferase 0.82 12.6 0.0 5.1 10.1 0.0 2.2 1 sp|Q6P2P2|ANM10_HUMAN Putative protein arginine N-methyltr 0.84 12.6 0.0 1.9 11.5 0.0 1.6 1 tr|K7ERS2|K7ERS2_HUMAN Methyltransferase-like protein 23 OS 0.85 12.6 0.0 1.4 11.9 0.0 1.3 1 tr|A8MXR3|A8MXR3_HUMAN Protein arginine N-methyltransferase 0.95 12.5 0.0 1.5 11.8 0.0 1.3 1 tr|H3BPG7|H3BPG7_HUMAN Anamorsin OS=Homo sapiens GN=CIAPIN1 0.96 12.4 0.0 1.9 11.5 0.0 1.5 1 sp|P55345-3|ANM2_HUMAN Isoform 3 of Protein arginine N-meth 1 12.4 0.0 2 11.4 0.0 1.5 1 sp|Q9UBP6|TRMB_HUMAN tRNA (guanine-N(7)-)-methyltransfera 1 12.4 0.0 2.2 11.3 0.0 1.6 1 tr|K7EJ00|K7EJ00_HUMAN Methyltransferase-like protein 23 OS Domain annotation for each sequence (and alignments): >> sp|Q8TCB7|METL6_HUMAN Methyltransferase-like protein 6 OS=Homo sapiens GN=METTL6 PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.8 0.1 3.7 2e+03 17 81 .. 21 59 .. 10 71 .. 0.50 2 ! 64.5 0.0 1.1e-19 5.7e-17 1 96 [. 84 182 .. 84 183 .. 0.92 Alignments for each domain: == domain 1 score: 1.8 bits; conditional E-value: 3.7 Methyltransf_12 17 klpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhlkd 81 kl++ + +++D+ ++ +e+ ++k +D+ + n + +kd sp|Q8TCB7|METL6_HUMAN 21 KLKRDQTLVSDFKQQKLEQEAQK--------------------------NWDLFYKRNSTNFFKD 59 33344444444444444444444..........................5555554444444444 PP == domain 2 score: 64.5 bits; conditional E-value: 1.1e-19 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.....ssfDvvvasnvlhhl..kd 81 Le GcG+G++l++lle+ p+i +++D+sp+ai e +++ +++++++++++dl ++d +s+Dvv +++vl+++ ++ sp|Q8TCB7|METL6_HUMAN 84 LEAGCGVGNCLFPLLEEDPNIFAYACDFSPRAI----EYVKQNPLYDTERCKVFQCDLTKDDLLdhvppESVDVVMLIFVLSAVhpDK 167 89*******************************....88888888888888888888877777788888****************999 PP Methyltransf_12 82 irealdniyklLkpg 96 ++ +l+niyk+Lkpg sp|Q8TCB7|METL6_HUMAN 168 MHLVLQNIYKVLKPG 182 9*************8 PP >> sp|Q8TCB7-2|METL6_HUMAN Isoform 2 of Methyltransferase-like protein 6 OS=Homo sapiens GN=METTL6 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.2 0.1 2.8 1.5e+03 17 81 .. 21 59 .. 10 71 .. 0.50 2 ! 55.0 0.0 1e-16 5.3e-14 1 92 [. 84 178 .. 84 180 .. 0.91 Alignments for each domain: == domain 1 score: 2.2 bits; conditional E-value: 2.8 Methyltransf_12 17 klpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhlkd 81 kl++ + +++D+ ++ +e+ ++k +D+ + n + +kd sp|Q8TCB7-2|METL6_HUMAN 21 KLKRDQTLVSDFKQQKLEQEAQK--------------------------NWDLFYKRNSTNFFKD 59 33344444444444444444444..........................5555555544444444 PP == domain 2 score: 55.0 bits; conditional E-value: 1e-16 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.....ssfDvvvasnvlhhl.. 79 Le GcG+G++l++lle+ p+i +++D+sp+ai e +++ +++++++++++dl ++d +s+Dvv +++vl+++ sp|Q8TCB7-2|METL6_HUMAN 84 LEAGCGVGNCLFPLLEEDPNIFAYACDFSPRAI----EYVKQNPLYDTERCKVFQCDLTKDDLLdhvppESVDVVMLIFVLSAVhp 165 89*******************************....88888888888888888888877777788888****************9 PP Methyltransf_12 80 kdirealdniykl 92 ++++ +l+niyk+ sp|Q8TCB7-2|METL6_HUMAN 166 DKMHLVLQNIYKC 178 9999*******96 PP >> sp|Q6P1Q9|MET2B_HUMAN Methyltransferase-like protein 2B OS=Homo sapiens GN=METTL2B PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 56.8 0.0 2.7e-17 1.4e-14 1 98 [. 185 287 .. 185 288 .. 0.85 Alignments for each domain: == domain 1 score: 56.8 bits; conditional E-value: 2.7e-17 Methyltransf_12 1 LeiGcGtGsllrallekl..pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.....ssfDvvvasnvlhhl.. 79 Le+GcG+G++++++l+ + p++ ++++D+s+ ai e + +++++ +++ ++ dl d+++ +s D++++++vl+++ sp|Q6P1Q9|MET2B_HUMAN 185 LEVGCGVGNTVFPILQTNndPGLFVYCCDFSSTAI----ELVQTNSEYDPSRCFAFVHDLCDEEKSypvpkGSLDIIILIFVLSAVvp 268 8******************9***************....5555555555555556666666555556779****************** PP Methyltransf_12 80 kdirealdniyklLkpgGr 98 +++++a++++ +lLkpgG+ sp|Q6P1Q9|MET2B_HUMAN 269 DKMQKAINRLSRLLKPGGM 287 ******************8 PP >> sp|Q96IZ6-2|MET2A_HUMAN Isoform 2 of Methyltransferase-like protein 2A OS=Homo sapiens GN=METTL2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.7 0.0 1.4e-17 7.4e-15 1 98 [. 49 151 .. 49 152 .. 0.85 Alignments for each domain: == domain 1 score: 57.7 bits; conditional E-value: 1.4e-17 Methyltransf_12 1 LeiGcGtGsllrallekl..pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.....ssfDvvvasnvlhhl 79 Le+GcG+G++++++l+ + p++ ++++D+s+ ai e + +++++ +++ ++ dl d+++ +s D++++++vl+++ sp|Q96IZ6-2|MET2A_HUMAN 49 LEVGCGVGNTVFPILQTNndPGLFVYCCDFSSTAI----ELVQTNSEYDPSRCFAFVHDLCDEEKSypvpkGSLDIIILIFVLSAI 130 8******************9***************....5555555555555556666666555556779**************** PP Methyltransf_12 80 ..kdirealdniyklLkpgGr 98 +++++a++++ +lLkpgG+ sp|Q96IZ6-2|MET2A_HUMAN 131 vpDKMQKAINRLSRLLKPGGM 151 ********************7 PP >> sp|Q96IZ6|MET2A_HUMAN Methyltransferase-like protein 2A OS=Homo sapiens GN=METTL2A PE=1 SV=5 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 56.4 0.0 3.6e-17 1.9e-14 1 98 [. 185 287 .. 185 288 .. 0.85 Alignments for each domain: == domain 1 score: 56.4 bits; conditional E-value: 3.6e-17 Methyltransf_12 1 LeiGcGtGsllrallekl..pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.....ssfDvvvasnvlhhl.. 79 Le+GcG+G++++++l+ + p++ ++++D+s+ ai e + +++++ +++ ++ dl d+++ +s D++++++vl+++ sp|Q96IZ6|MET2A_HUMAN 185 LEVGCGVGNTVFPILQTNndPGLFVYCCDFSSTAI----ELVQTNSEYDPSRCFAFVHDLCDEEKSypvpkGSLDIIILIFVLSAIvp 268 8******************9***************....5555555555555556666666555556779****************** PP Methyltransf_12 80 kdirealdniyklLkpgGr 98 +++++a++++ +lLkpgG+ sp|Q96IZ6|MET2A_HUMAN 269 DKMQKAINRLSRLLKPGGM 287 ******************7 PP >> sp|Q6P1Q9-2|MET2B_HUMAN Isoform 2 of Methyltransferase-like protein 2B OS=Homo sapiens GN=METTL2B # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 57.3 0.0 1.9e-17 9.9e-15 1 98 [. 120 222 .. 120 223 .. 0.85 Alignments for each domain: == domain 1 score: 57.3 bits; conditional E-value: 1.9e-17 Methyltransf_12 1 LeiGcGtGsllrallekl..pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.....ssfDvvvasnvlhhl 79 Le+GcG+G++++++l+ + p++ ++++D+s+ ai e + +++++ +++ ++ dl d+++ +s D++++++vl+++ sp|Q6P1Q9-2|MET2B_HUMAN 120 LEVGCGVGNTVFPILQTNndPGLFVYCCDFSSTAI----ELVQTNSEYDPSRCFAFVHDLCDEEKSypvpkGSLDIIILIFVLSAV 201 8******************9***************....5555555555555556666666555556779**************** PP Methyltransf_12 80 ..kdirealdniyklLkpgGr 98 +++++a++++ +lLkpgG+ sp|Q6P1Q9-2|MET2B_HUMAN 202 vpDKMQKAINRLSRLLKPGGM 222 ********************8 PP >> sp|Q6UX53|MET7B_HUMAN Methyltransferase-like protein 7B OS=Homo sapiens GN=METTL7B PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 53.7 0.0 2.6e-16 1.4e-13 1 99 [] 75 170 .. 75 170 .. 0.96 Alignments for each domain: == domain 1 score: 53.7 bits; conditional E-value: 2.6e-16 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhlkdirealdn 88 Le+GcGtG++ + + +++t++D++p++ + + +a++++ + +++ + ++ + +s Dvvv+ vl+ ++ +r++l++ sp|Q6UX53|MET7B_HUMAN 75 LELGCGTGANFQFYPPG---CRVTCLDPNPHFEKFLTKSMAENRHLQYERFVVAPGEDMRQLADGSMDVVVCTLVLCSVQSPRKVLQE 159 8**********999666...***********************************9999999999*********************** PP Methyltransf_12 89 iyklLkpgGrl 99 ++++L+pgG+l sp|Q6UX53|MET7B_HUMAN 160 VRRVLRPGGVL 170 *********97 PP >> sp|Q9NZJ6|COQ3_HUMAN Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial OS=Homo sapiens GN=COQ3 PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 50.0 0.0 3.6e-15 1.9e-12 1 99 [] 151 248 .. 151 248 .. 0.95 Alignments for each domain: == domain 1 score: 50.0 bits; conditional E-value: 3.6e-15 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg..ssfDvvvasnvlhhlkdireald 87 L++GcG G l+++l + +++++g+D+ + i ++++ +++ ++ +++++++++l++ ++ ++fD+vvas+v++h+ d++ +l+ sp|Q9NZJ6|COQ3_HUMAN 151 LDVGCGGGLLTEPLGRL--GASVIGIDPVDENI-KTAQCHKSFDPVLDKRIEYRVCSLEEIVEEtaETFDAVVASEVVEHVIDLETFLQ 236 8****************..**************.88888888899999*********988777799*********************** PP Methyltransf_12 88 niyklLkpgGrl 99 + ++LkpgG l sp|Q9NZJ6|COQ3_HUMAN 237 CCCQVLKPGGSL 248 **********76 PP >> tr|F8VQX6|F8VQX6_HUMAN Methyltransferase-like protein 7A (Fragment) OS=Homo sapiens GN=METTL7A PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 49.2 0.0 6.4e-15 3.4e-12 1 98 [. 75 169 .. 75 170 .. 0.89 Alignments for each domain: == domain 1 score: 49.2 bits; conditional E-value: 6.4e-15 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhlkdireald 87 Le+GcGtG++ + + +++t++D++p++ + + +a++++ +++++ + a + + +s+Dvvv+ vl+ +k+ +++l+ tr|F8VQX6|F8VQX6_HUMAN 75 LEVGCGTGANFKFYPPG---CRVTCIDPNPNFEKFLIKSIAENRHLQFERFVVAAGENMHQVADGSVDVVVCTLVLCSVKNQERILR 158 8*********9999666...*************98889999888888888887777766666668********************** PP Methyltransf_12 88 niyklLkpgGr 98 ++ ++L+pgG tr|F8VQX6|F8VQX6_HUMAN 159 EVCRVLRPGGA 169 **********6 PP >> sp|Q9H8H3|MET7A_HUMAN Methyltransferase-like protein 7A OS=Homo sapiens GN=METTL7A PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 48.1 0.0 1.3e-14 7.1e-12 1 98 [. 75 169 .. 75 170 .. 0.89 Alignments for each domain: == domain 1 score: 48.1 bits; conditional E-value: 1.3e-14 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhlkdirealdn 88 Le+GcGtG++ + + +++t++D++p++ + + +a++++ +++++ + a + + +s+Dvvv+ vl+ +k+ +++l++ sp|Q9H8H3|MET7A_HUMAN 75 LEVGCGTGANFKFYPPG---CRVTCIDPNPNFEKFLIKSIAENRHLQFERFVVAAGENMHQVADGSVDVVVCTLVLCSVKNQERILRE 159 8*********9999666...*************98889999888888888887777766666668*********************** PP Methyltransf_12 89 iyklLkpgGr 98 + ++L+pgG sp|Q9H8H3|MET7A_HUMAN 160 VCRVLRPGGA 169 *********6 PP >> tr|H0YI09|H0YI09_HUMAN Methyltransferase-like protein 7A (Fragment) OS=Homo sapiens GN=METTL7A PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 48.1 0.0 1.3e-14 7.1e-12 1 98 [. 75 169 .. 75 170 .. 0.89 Alignments for each domain: == domain 1 score: 48.1 bits; conditional E-value: 1.3e-14 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhlkdireald 87 Le+GcGtG++ + + +++t++D++p++ + + +a++++ +++++ + a + + +s+Dvvv+ vl+ +k+ +++l+ tr|H0YI09|H0YI09_HUMAN 75 LEVGCGTGANFKFYPPG---CRVTCIDPNPNFEKFLIKSIAENRHLQFERFVVAAGENMHQVADGSVDVVVCTLVLCSVKNQERILR 158 8*********9999666...*************98889999888888888887777766666668********************** PP Methyltransf_12 88 niyklLkpgGr 98 ++ ++L+pgG tr|H0YI09|H0YI09_HUMAN 159 EVCRVLRPGGA 169 **********6 PP >> tr|E7ETE0|E7ETE0_HUMAN Methyltransferase-like protein 8 OS=Homo sapiens GN=METTL8 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 43.3 0.0 4.5e-13 2.4e-10 1 99 [] 201 305 .. 201 305 .. 0.81 Alignments for each domain: == domain 1 score: 43.3 bits; conditional E-value: 4.5e-13 Methyltransf_12 1 LeiGcGtGsllrallekl...pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg..ssfDvvvasnvlhhl..k 80 Le+GcG G+ ++++l+ l p++ ++++D+ + a+e k + + r +++++v +++d++ + + Dv+++ +vl+ + + tr|E7ETE0|E7ETE0_HUMAN 201 LEVGCGAGNSVFPILNTLensPESFLYCCDFASGAVELVKSHSSYRATQCFAFV-HDVCDDGLPYPFpdGILDVILLVFVLSSIhpD 286 8*******************9999999*********555555444444444444.444444433333799***************99 PP Methyltransf_12 81 direaldniyklLkpgGrl 99 ++ +++++ klLkpgG+l tr|E7ETE0|E7ETE0_HUMAN 287 RMQGVVNRLSKLLKPGGML 305 9****************97 PP >> tr|B3KR61|B3KR61_HUMAN HCG1811060, isoform CRA_c OS=Homo sapiens GN=NDUFAF5 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 42.9 0.0 5.9e-13 3.1e-10 1 99 [] 94 184 .. 94 184 .. 0.79 Alignments for each domain: == domain 1 score: 42.9 bits; conditional E-value: 5.9e-13 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhlkdireald 87 L++GcG G ++++l ++ ++ Di ++a+ + ++ v + a + + ++++fD+vv+s lh+++d+ +al+ tr|B3KR61|B3KR61_HUMAN 94 LDLGCGRGYIAQYLNKE-TIGKFFQADIAENAL----KNSSET---EIPTVSVLADEEFLPFKENTFDLVVSSLSLHWVNDLPRALE 172 8*************999.8889999********....222222...2334444444434444447********************** PP Methyltransf_12 88 niyklLkpgGrl 99 +i+ Lkp+G++ tr|B3KR61|B3KR61_HUMAN 173 QIHYILKPDGVF 184 **********86 PP >> sp|Q5TEU4|NDUF5_HUMAN NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 5 OS=Homo sapiens GN=NDUFAF # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 42.2 0.0 9.8e-13 5.1e-10 1 99 [] 94 184 .. 94 184 .. 0.79 Alignments for each domain: == domain 1 score: 42.2 bits; conditional E-value: 9.8e-13 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhlkdirealdn 88 L++GcG G ++++l ++ ++ Di ++a+ + ++ v + a + + ++++fD+vv+s lh+++d+ +al++ sp|Q5TEU4|NDUF5_HUMAN 94 LDLGCGRGYIAQYLNKE-TIGKFFQADIAENAL----KNSSET---EIPTVSVLADEEFLPFKENTFDLVVSSLSLHWVNDLPRALEQ 173 8*************999.8889999********....222222...2334444444434444447*********************** PP Methyltransf_12 89 iyklLkpgGrl 99 i+ Lkp+G++ sp|Q5TEU4|NDUF5_HUMAN 174 IHYILKPDGVF 184 *********86 PP >> sp|Q9HBK9|AS3MT_HUMAN Arsenite methyltransferase OS=Homo sapiens GN=AS3MT PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 39.4 0.1 7.3e-12 3.9e-09 1 99 [] 75 181 .. 75 181 .. 0.82 Alignments for each domain: == domain 1 score: 39.4 bits; conditional E-value: 7.3e-12 Methyltransf_12 1 LeiGcGtGsllrallekl.pdieytgvDispsai...edakeklakrennnnnnvnlealdlldldgg....ssfDvvvasnvlhhlk 80 L++G+G+G+ +l + + ++tg+D + ++ e+ + ++ + +++nv++ + +++l + +s D+vv+++v++ ++ sp|Q9HBK9|AS3MT_HUMAN 75 LDLGSGSGRDCYVLSQLVgEKGHVTGIDMTKGQVevaEKYLDYHMEKYGFQASNVTFIHGYIEKLGEAgiknESHDIVVSNCVINLVP 162 8***********99999999**************33333333333444456677777777766555559******************* PP Methyltransf_12 81 direaldniyklLkpgGrl 99 d++++l+++y++Lk gG l sp|Q9HBK9|AS3MT_HUMAN 163 DKQQVLQEAYRVLKHGGEL 181 *****************76 PP >> sp|Q9BV86|NTM1A_HUMAN N-terminal Xaa-Pro-Lys N-methyltransferase 1 OS=Homo sapiens GN=NTMT1 PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 38.2 0.0 1.8e-11 9.2e-09 1 99 [] 66 163 .. 66 163 .. 0.84 Alignments for each domain: == domain 1 score: 38.2 bits; conditional E-value: 1.8e-11 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhl..kdireal 86 L+ G+G G+++++ll e+ vDi ++++ +ak+ l +++++ n+ l+++ +++s+Dv+++ v+ hl ++++e+l sp|Q9BV86|NTM1A_HUMAN 66 LDCGAGIGRITKRLLLP-LFREVDMVDITEDFLVQAKTYLGEEGKRV-RNYFCCGLQDFTP-EPDSYDVIWIQWVIGHLtdQHLAEFL 150 899**********9988.899************99999999988644.3333333443444.347**************999999*** PP Methyltransf_12 87 dniyklLkpgGrl 99 ++++ L+p+G++ sp|Q9BV86|NTM1A_HUMAN 151 RRCKGSLRPNGII 163 ***********85 PP >> sp|Q7L2J0|MEPCE_HUMAN 7SK snRNA methylphosphate capping enzyme OS=Homo sapiens GN=MEPCE PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.5 0.0 2.3e-05 0.012 1 43 [. 448 490 .. 448 509 .. 0.92 2 ! 17.6 0.0 4.4e-05 0.023 57 99 .] 566 613 .. 545 613 .. 0.80 Alignments for each domain: == domain 1 score: 18.5 bits; conditional E-value: 2.3e-05 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakr 43 L++Gc++G+l+ ++ k +++ +g+Di+++ i+ a++ ++++ sp|Q7L2J0|MEPCE_HUMAN 448 LDLGCNVGHLTLSIACKWGPSRMVGLDIDSRLIHSARQNIRHY 490 8********************************9999998876 PP == domain 2 score: 17.6 bits; conditional E-value: 4.4e-05 Methyltransf_12 57 dlldldgg..ssfDvvvasnvlhhl......kdirealdniyklLkpgGrl 99 dl + +Dvv+++++ ++ + +++++++iy++L+pgG+l sp|Q7L2J0|MEPCE_HUMAN 566 DLVE---AqtPEYDVVLCLSLTKWVhlnwgdEGLKRMFRRIYRHLRPGGIL 613 2222...13369*************************************86 PP >> tr|F8VVX6|F8VVX6_HUMAN 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial (Fragment) OS=Homo sapiens GN # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 35.8 0.1 9.3e-11 4.9e-08 1 99 [] 30 161 .. 30 161 .. 0.87 Alignments for each domain: == domain 1 score: 35.8 bits; conditional E-value: 9.3e-11 Methyltransf_12 1 LeiGcGtGsllrallekl..................................pdieytgvDispsaiedakeklakrennnnnnvnl 53 L++ +GtG++++++l++ +++++++Di++++++ k+k +++ + + l tr|F8VVX6|F8VVX6_HUMAN 30 LDVAGGTGDIAFRFLNYVqsqhqrkqkrqlraqqnlsweeiakeyqneedslGGSRVVVCDINKEMLKVGKQKALAQGYRAGLAWVL 116 89999999999999999999999999999999999999999999999999999**************99999988888877655555 PP Methyltransf_12 54 ealdlldldgg.ssfDvvvasnvlhhlkdirealdniyklLkpgGrl 99 + + l ++fD+ ++++ + ++ +i++al++++++LkpgGr+ tr|F8VVX6|F8VVX6_HUMAN 117 GDAEELPF--DdDKFDIYTIAFGIRNVTHIDQALQEAHRVLKPGGRF 161 54443322..236********************************96 PP >> sp|Q9P272|K1456_HUMAN Putative methyltransferase KIAA1456 OS=Homo sapiens GN=KIAA1456 PE=2 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 37.2 0.0 3.5e-11 1.8e-08 2 99 .] 50 137 .. 49 137 .. 0.78 Alignments for each domain: == domain 1 score: 37.2 bits; conditional E-value: 3.5e-11 Methyltransf_12 2 eiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhl..kdir.eal 86 +iGcGtG +l++ +++ +g+D+ +e a+++ + ++l+l +d+ fD++++++v+hh+ k++r +a+ sp|Q9P272|K1456_HUMAN 50 DIGCGTGKYLKVNS----QVHTVGCDYCGPLVEIARNRGCEAM-------VCDNLNLPFRDE--GFDAIISIGVIHHFstKQRRiRAI 124 8******9988764....66************55555544433.......333334334444..8*************9977777*** PP Methyltransf_12 87 dniyklLkpgGrl 99 ++++++L+pgG+l sp|Q9P272|K1456_HUMAN 125 KEMARVLVPGGQL 137 ***********97 PP >> tr|H7C2P8|H7C2P8_HUMAN Methyltransferase-like protein 8 (Fragment) OS=Homo sapiens GN=METTL8 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 35.7 0.0 1e-10 5.4e-08 1 99 [] 24 141 .. 24 141 .. 0.88 Alignments for each domain: == domain 1 score: 35.7 bits; conditional E-value: 1e-10 Methyltransf_12 1 LeiGcGtGsllrallekl...pdieytgvDispsai.........edakeklakrennnnnnvnlealdlldldgg.....ssfDvv 70 Le+GcG G+ ++++l+ l p++ ++++D+ + a+ e ++ ++++ ++++++ ++ d+ d+ + + Dv+ tr|H7C2P8|H7C2P8_HUMAN 24 LEVGCGAGNSVFPILNTLensPESFLYCCDFASGAVelvkvcyswESYQLMPKSHSSYRATQCFAFVHDVCDDGLPypfpdGILDVI 110 8*******************9999999*********8888888887777777777777777777777777666555899******** PP Methyltransf_12 71 vasnvlhhl..kdirealdniyklLkpgGrl 99 ++ +vl+ + + ++ +++++ klLkpgG+l tr|H7C2P8|H7C2P8_HUMAN 111 LLVFVLSSIhpDRMQGVVNRLSKLLKPGGML 141 **********999****************97 PP >> sp|Q14749|GNMT_HUMAN Glycine N-methyltransferase OS=Homo sapiens GN=GNMT PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 36.6 0.0 5.2e-11 2.8e-08 1 99 [] 62 173 .. 62 173 .. 0.93 Alignments for each domain: == domain 1 score: 36.6 bits; conditional E-value: 5.2e-11 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsai.edakeklakrennnnnnvnlealdlldldgg......ssfDvvvas.nvlhhl.. 79 L++ cGtG + +l e+ + ++t vD s +++ + ke+ ++r++ ++++ +e+ + ld+ + fD+v+++ n + hl sp|Q14749|GNMT_HUMAN 62 LDVACGTGVDSIMLVEE--GFSVTSVDASDKMLkYALKERWNRRHEPAFDKWVIEEANWMTLDKDvpqsaeGGFDAVICLgNSFAHLpd 148 8****************..**************666688888889999999999999999999999*********************** PP Methyltransf_12 80 .....kdirealdniyklLkpgGrl 99 + r al+ni+++++ gG l sp|Q14749|GNMT_HUMAN 149 ckgdqSEHRLALKNIASMVRAGGLL 173 **99989999*************86 PP >> tr|H7C3H9|H7C3H9_HUMAN Methyltransferase-like protein 6 (Fragment) OS=Homo sapiens GN=METTL6 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 36.3 0.0 6.7e-11 3.5e-08 12 92 .. 2 85 .. 1 87 [. 0.88 Alignments for each domain: == domain 1 score: 36.3 bits; conditional E-value: 6.7e-11 Methyltransf_12 12 ralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.....ssfDvvvasnvlhhl..kdirealdniykl 92 ++lle+ p+i +++D+sp+ai e +++ +++++++++++dl ++d +s+Dvv +++vl+++ ++++ +l+niyk+ tr|H7C3H9|H7C3H9_HUMAN 2 FPLLEEDPNIFAYACDFSPRAI----EYVKQNPLYDTERCKVFQCDLTKDDLLdhvppESVDVVMLIFVLSAVhpDKMHLVLQNIYKC 85 67889999**************....88888888888888888888877777788888****************99999*******96 PP >> sp|Q5HYK3|COQ5_HUMAN 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial OS=Homo sapiens GN=COQ5 PE=1 SV # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 34.4 0.1 2.7e-10 1.4e-07 1 99 [] 111 242 .. 111 242 .. 0.87 Alignments for each domain: == domain 1 score: 34.4 bits; conditional E-value: 2.7e-10 Methyltransf_12 1 LeiGcGtGsllrallekl..................................pdieytgvDispsaiedakeklakrennnnnnvnlea 55 L++ +GtG++++++l++ +++++++Di++++++ k+k +++ + + l + sp|Q5HYK3|COQ5_HUMAN 111 LDVAGGTGDIAFRFLNYVqsqhqrkqkrqlraqqnlsweeiakeyqneedslGGSRVVVCDINKEMLKVGKQKALAQGYRAGLAWVLGD 199 89999999999999999999999999999999999999999999999999999**************9999998888887765555554 PP Methyltransf_12 56 ldlldldgg.ssfDvvvasnvlhhlkdirealdniyklLkpgGrl 99 + l ++fD+ ++++ + ++ +i++al++++++LkpgGr+ sp|Q5HYK3|COQ5_HUMAN 200 AEELPF--DdDKFDIYTIAFGIRNVTHIDQALQEAHRVLKPGGRF 242 443322..236********************************96 PP >> tr|H3BQD2|H3BQD2_HUMAN Methyltransferase-like protein 9 (Fragment) OS=Homo sapiens GN=METTL9 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 36.2 0.0 6.9e-11 3.6e-08 1 95 [. 21 102 .. 21 107 .. 0.87 Alignments for each domain: == domain 1 score: 36.2 bits; conditional E-value: 6.9e-11 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhlkdireald 87 L++G+G+G++++ + ++ e++++++s+ +i +l+k++ + ++++++ ++Dv+ ++n+l ++++ +l+ tr|H3BQD2|H3BQD2_HUMAN 21 LDLGAGDGEVTKIMSPH--FEEIYATELSETMI----WQLQKKKYRVLGINEWQNTGF-------QYDVISCLNLLDRCDQPLTLLK 94 8****************..**************....666666665666666666553.......9********************* PP Methyltransf_12 88 niyklLkp 95 i+++L p tr|H3BQD2|H3BQD2_HUMAN 95 DIRSVLEP 102 ******99 PP >> tr|H3BM54|H3BM54_HUMAN Methyltransferase-like protein 9 (Fragment) OS=Homo sapiens GN=METTL9 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 35.9 0.0 8.8e-11 4.6e-08 1 95 [. 39 120 .. 39 125 .. 0.87 Alignments for each domain: == domain 1 score: 35.9 bits; conditional E-value: 8.8e-11 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhlkdireald 87 L++G+G+G++++ + ++ e++++++s+ +i +l+k++ + ++++++ ++Dv+ ++n+l ++++ +l+ tr|H3BM54|H3BM54_HUMAN 39 LDLGAGDGEVTKIMSPH--FEEIYATELSETMI----WQLQKKKYRVLGINEWQNTGF-------QYDVISCLNLLDRCDQPLTLLK 112 8****************..**************....666666665666666666553.......9********************* PP Methyltransf_12 88 niyklLkp 95 i+++L p tr|H3BM54|H3BM54_HUMAN 113 DIRSVLEP 120 ******99 PP >> tr|H3BN86|H3BN86_HUMAN Methyltransferase-like protein 9 (Fragment) OS=Homo sapiens GN=METTL9 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 34.0 0.0 3.5e-10 1.8e-07 1 95 [. 110 191 .. 110 196 .. 0.87 Alignments for each domain: == domain 1 score: 34.0 bits; conditional E-value: 3.5e-10 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhlkdireald 87 L++G+G+G++++ + ++ e++++++s+ +i +l+k++ + ++++++ ++Dv+ ++n+l ++++ +l+ tr|H3BN86|H3BN86_HUMAN 110 LDLGAGDGEVTKIMSPH--FEEIYATELSETMI----WQLQKKKYRVLGINEWQNTGF-------QYDVISCLNLLDRCDQPLTLLK 183 8****************..**************....666666665666666666553.......9********************* PP Methyltransf_12 88 niyklLkp 95 i+++L p tr|H3BN86|H3BN86_HUMAN 184 DIRSVLEP 191 ******99 PP >> tr|B4DDX3|B4DDX3_HUMAN Methyltransferase-like protein 6 OS=Homo sapiens GN=METTL6 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.2 1.0 5.4e-09 2.8e-06 43 96 .. 82 137 .. 10 138 .. 0.80 Alignments for each domain: == domain 1 score: 30.2 bits; conditional E-value: 5.4e-09 Methyltransf_12 43 rennnnnnvnlealdlldldggssfDvvvasnvlhhl..kdirealdniyklLkpg 96 e+ ++ +++l + dlld+ +++s+Dvv +++vl+++ ++++ +l+niyk+Lkpg tr|B4DDX3|B4DDX3_HUMAN 82 TERCKVFQCDLTKDDLLDHVPPESVDVVMLIFVLSAVhpDKMHLVLQNIYKVLKPG 137 3344445555555555555555****************9999*************8 PP >> sp|Q9H1A3-2|METL9_HUMAN Isoform 2 of Methyltransferase-like protein 9 OS=Homo sapiens GN=METTL9 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.3 0.0 5.9e-10 3.1e-07 1 95 [. 150 231 .. 150 236 .. 0.87 Alignments for each domain: == domain 1 score: 33.3 bits; conditional E-value: 5.9e-10 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhlkdireal 86 L++G+G+G++++ + ++ e++++++s+ +i +l+k++ + ++++++ ++Dv+ ++n+l ++++ +l sp|Q9H1A3-2|METL9_HUMAN 150 LDLGAGDGEVTKIMSPH--FEEIYATELSETMI----WQLQKKKYRVLGINEWQNTGF-------QYDVISCLNLLDRCDQPLTLL 222 8****************..**************....666666665666666666553.......9******************** PP Methyltransf_12 87 dniyklLkp 95 + i+++L p sp|Q9H1A3-2|METL9_HUMAN 223 KDIRSVLEP 231 *******99 PP >> sp|Q9H1A3|METL9_HUMAN Methyltransferase-like protein 9 OS=Homo sapiens GN=METTL9 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.2 0.0 5.9e-10 3.1e-07 1 95 [. 150 231 .. 150 236 .. 0.87 Alignments for each domain: == domain 1 score: 33.2 bits; conditional E-value: 5.9e-10 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhlkdirealdn 88 L++G+G+G++++ + ++ e++++++s+ +i +l+k++ + ++++++ ++Dv+ ++n+l ++++ +l+ sp|Q9H1A3|METL9_HUMAN 150 LDLGAGDGEVTKIMSPH--FEEIYATELSETMI----WQLQKKKYRVLGINEWQNTGF-------QYDVISCLNLLDRCDQPLTLLKD 224 8****************..**************....666666665666666666553.......9********************** PP Methyltransf_12 89 iyklLkp 95 i+++L p sp|Q9H1A3|METL9_HUMAN 225 IRSVLEP 231 *****99 PP >> sp|O60344-4|ECE2_HUMAN Isoform D of Endothelin-converting enzyme 2 OS=Homo sapiens GN=ECE2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.2 0.0 6.2e-10 3.3e-07 1 99 [] 63 171 .. 63 171 .. 0.92 Alignments for each domain: == domain 1 score: 33.2 bits; conditional E-value: 6.2e-10 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhl........ 79 L +GcG+++l+ +l ++t vD+s+ ++++ ++++a+ + +++ +++++ld + +sfDvv+ ++l +l sp|O60344-4|ECE2_HUMAN 63 LVLGCGNSALSYELFLG-GFPNVTSVDYSSVVVAAMQARHAHVPQLRWETMDVRKLDFPS----ASFDVVLEKGTLDALlagerdpw 144 569**********9888.99*************999999999998888888888888654....5********************** PP Methyltransf_12 80 .......kdirealdniyklLkpgGrl 99 +++++l+++ ++L+pgGr+ sp|O60344-4|ECE2_HUMAN 145 tvssegvHTVDQVLSEVSRVLVPGGRF 171 *************************96 PP >> sp|P46597|ASMT_HUMAN Acetylserotonin O-methyltransferase OS=Homo sapiens GN=ASMT PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 32.8 0.0 8.1e-10 4.3e-07 2 98 .. 185 278 .. 184 279 .. 0.91 Alignments for each domain: == domain 1 score: 32.8 bits; conditional E-value: 8.1e-10 Methyltransf_12 2 eiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhl..kdirealdn 88 ++G+G G+l++++ p++++t+ Di + + ak++++++e+ +++++++ d ++++ + D+ +++ vlh + + +l++ sp|P46597|ASMT_HUMAN 185 DLGGGAGALAKECMSLYPGCKITVFDIPEVVW-TAKQHFSFQEE---EQIDFQEGDFFKDPLP-EADLYILARVLHDWadGKCSHLLER 268 89*****************************9.********997...7888888887777776.**************777777***** PP Methyltransf_12 89 iyklLkpgGr 98 iy+ +kpgG sp|P46597|ASMT_HUMAN 269 IYHTCKPGGG 278 ********96 PP >> sp|P49327|FAS_HUMAN Fatty acid synthase OS=Homo sapiens GN=FASN PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 31.9 0.0 1.6e-09 8.4e-07 2 99 .] 1244 1342 .. 1243 1342 .. 0.87 Alignments for each domain: == domain 1 score: 31.9 bits; conditional E-value: 1.6e-09 Methyltransf_12 2 eiGcGtGsllrallekl.....pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhlkdire 84 e+ +G G+l +++ l +++yt++D +p+a+e+a+++l++++ +++ +++ d + ++ g s D+ v+++++ +l d+++ sp|P49327|FAS_HUMAN 1244 EVLAGHGHLYSRIPGLLsphplLQLSYTATDRHPQALEAAQAELQQHD---VAQGQWDPADPAPSALG-SADLLVCNCAVAALGDPAS 1327 788999*****999999999999**************77777777766...67777777777666665.******************* PP Methyltransf_12 85 aldniyklLkpgGrl 99 al+n+ ++L+ gG l sp|P49327|FAS_HUMAN 1328 ALSNMVAALREGGFL 1342 *************86 PP >> sp|P50135|HNMT_HUMAN Histamine N-methyltransferase OS=Homo sapiens GN=HNMT PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 31.3 0.0 2.4e-09 1.3e-06 1 98 [. 57 167 .. 57 168 .. 0.92 Alignments for each domain: == domain 1 score: 31.3 bits; conditional E-value: 2.4e-09 Methyltransf_12 1 LeiGcGtGsllrallekl......pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.......ssfDvvvasnvl 76 L iG+G G++ +l k i+ +v++s+++i++ ke ak +n n ++ + ++ ++ +++ +++D +++++ l sp|P50135|HNMT_HUMAN 57 LSIGGGAGEIDLQILSKVqaqypgVCINNEVVEPSAEQIAKYKELVAKTSNLENVKFAWHKETSSEYQSRmlekkelQKWDFIHMIQML 145 679*****9999999998899887778888999**************************99999998888******************* PP Methyltransf_12 77 hhlkdirealdniyklLkpgGr 98 ++kdi ++l+ +++lL +++ sp|P50135|HNMT_HUMAN 146 YYVKDIPATLKFFHSLLGTNAK 167 *****************98875 PP >> sp|Q8N6R0-1|MET13_HUMAN Isoform 4 of Methyltransferase-like protein 13 OS=Homo sapiens GN=METTL13 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.1 0.0 1.8e-06 0.00093 1 98 [. 53 148 .. 53 149 .. 0.80 2 ? 5.3 0.0 0.31 1.7e+02 1 44 [. 342 385 .. 342 420 .. 0.82 Alignments for each domain: == domain 1 score: 22.1 bits; conditional E-value: 1.8e-06 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.ssfDvvvasnvlhhl..kdir 83 L iGcG+++l++ l + +++ +Dis+ +i +++++ ++ + ++ + + d+ + + + +sf vv+ ++l ++ ++ + sp|Q8N6R0-1|MET13_HUMAN 53 LVIGCGNSELSEQLYDV-GYRDIVNIDISEVVI----KQMKECNATRRPQMSFLKMDMTQMEFPdASFQVVLDKGTLDAVltDEEE 133 569***********999.9999***********....44444444444566666666555555567***************88888 PP Methyltransf_12 84 ealdniyklLkpgGr 98 ++l+++ ++L+ Gr sp|Q8N6R0-1|MET13_HUMAN 134 KTLQQVDRMLAEVGR 148 **********98776 PP == domain 2 score: 5.3 bits; conditional E-value: 0.31 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakre 44 L +G G Gsl + +++p + + +v+i+ps++e a + + + + sp|Q8N6R0-1|MET13_HUMAN 342 LVVGLGGGSLPLFVHDHFPKSCIDAVEIDPSMLEVATQWFGFSQ 385 56899****************************88887666555 PP >> sp|Q8N6R0-4|MET13_HUMAN Isoform 2 of Methyltransferase-like protein 13 OS=Homo sapiens GN=METTL13 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.0 0.0 1.9e-06 0.001 1 98 [. 53 148 .. 53 155 .. 0.78 2 ? 4.9 0.0 0.39 2.1e+02 2 44 .. 499 541 .. 498 576 .. 0.82 Alignments for each domain: == domain 1 score: 22.0 bits; conditional E-value: 1.9e-06 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.ssfDvvvasnvlhhl..kdir 83 L iGcG+++l++ l + +++ +Dis+ +i +++++ ++ + ++ + + d+ + + + +sf vv+ ++l ++ ++ + sp|Q8N6R0-4|MET13_HUMAN 53 LVIGCGNSELSEQLYDV-GYRDIVNIDISEVVI----KQMKECNATRRPQMSFLKMDMTQMEFPdASFQVVLDKGTLDAVltDEEE 133 569***********999.9999***********....44444444444566666666555555567***************87777 PP Methyltransf_12 84 ealdniyklLkpgGr 98 ++l+++ ++L+ Gr sp|Q8N6R0-4|MET13_HUMAN 134 KTLQQVDRMLAEVGR 148 899998888887665 PP == domain 2 score: 4.9 bits; conditional E-value: 0.39 Methyltransf_12 2 eiGcGtGsllralleklpdieytgvDispsaiedakeklakre 44 +G G Gsl + +++p + + +v+i+ps++e a + + + + sp|Q8N6R0-4|MET13_HUMAN 499 VVGLGGGSLPLFVHDHFPKSCIDAVEIDPSMLEVATQWFGFSQ 541 6899****************************88887666555 PP >> sp|Q8N6R0|MET13_HUMAN Methyltransferase-like protein 13 OS=Homo sapiens GN=METTL13 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.8 0.0 2.2e-06 0.0011 1 98 [. 53 148 .. 53 155 .. 0.78 2 ? 4.8 0.0 0.44 2.3e+02 2 44 .. 499 541 .. 498 576 .. 0.82 Alignments for each domain: == domain 1 score: 21.8 bits; conditional E-value: 2.2e-06 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.ssfDvvvasnvlhhl..kdirea 85 L iGcG+++l++ l + +++ +Dis+ +i +++++ ++ + ++ + + d+ + + + +sf vv+ ++l ++ ++ +++ sp|Q8N6R0|MET13_HUMAN 53 LVIGCGNSELSEQLYDV-GYRDIVNIDISEVVI----KQMKECNATRRPQMSFLKMDMTQMEFPdASFQVVLDKGTLDAVltDEEEKT 135 569***********999.9999***********....44444444444566666666555555567***************8777789 PP Methyltransf_12 86 ldniyklLkpgGr 98 l+++ ++L+ Gr sp|Q8N6R0|MET13_HUMAN 136 LQQVDRMLAEVGR 148 9999888887665 PP == domain 2 score: 4.8 bits; conditional E-value: 0.44 Methyltransf_12 2 eiGcGtGsllralleklpdieytgvDispsaiedakeklakre 44 +G G Gsl + +++p + + +v+i+ps++e a + + + + sp|Q8N6R0|MET13_HUMAN 499 VVGLGGGSLPLFVHDHFPKSCIDAVEIDPSMLEVATQWFGFSQ 541 6899****************************88887666555 PP >> tr|B4E2X3|B4E2X3_HUMAN Methyltransferase-like protein 13 OS=Homo sapiens GN=METTL13 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.8 0.0 2.2e-06 0.0011 1 98 [. 52 147 .. 52 154 .. 0.78 2 ? 4.8 0.0 0.44 2.3e+02 2 44 .. 498 540 .. 497 575 .. 0.82 Alignments for each domain: == domain 1 score: 21.8 bits; conditional E-value: 2.2e-06 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.ssfDvvvasnvlhhl..kdire 84 L iGcG+++l++ l + +++ +Dis+ +i +++++ ++ + ++ + + d+ + + + +sf vv+ ++l ++ ++ ++ tr|B4E2X3|B4E2X3_HUMAN 52 LVIGCGNSELSEQLYDV-GYRDIVNIDISEVVI----KQMKECNATRRPQMSFLKMDMTQMEFPdASFQVVLDKGTLDAVltDEEEK 133 569***********999.9999***********....44444444444566666666555555567***************877778 PP Methyltransf_12 85 aldniyklLkpgGr 98 +l+++ ++L+ Gr tr|B4E2X3|B4E2X3_HUMAN 134 TLQQVDRMLAEVGR 147 99999888887665 PP == domain 2 score: 4.8 bits; conditional E-value: 0.44 Methyltransf_12 2 eiGcGtGsllralleklpdieytgvDispsaiedakeklakre 44 +G G Gsl + +++p + + +v+i+ps++e a + + + + tr|B4E2X3|B4E2X3_HUMAN 498 VVGLGGGSLPLFVHDHFPKSCIDAVEIDPSMLEVATQWFGFSQ 540 6899****************************88887666555 PP >> tr|H3BQF6|H3BQF6_HUMAN Uncharacterized protein (Fragment) OS=Homo sapiens PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.2 0.0 5.2e-09 2.7e-06 1 98 [. 49 151 .. 49 152 .. 0.73 Alignments for each domain: == domain 1 score: 30.2 bits; conditional E-value: 5.2e-09 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg..........ssfDvvvasnvlh 77 L+iG+G+G +l +l++ +++tg+D+spsai + + + ++e+ +n++l+++d l+l + ++fD+ tr|H3BQF6|H3BQF6_HUMAN 49 LDIGTGNGVFLVELAKF-GFSNITGIDYSPSAI-QLSGSIIEKEG--LSNIKLKVEDFLNLSTQlsgfhicidkGTFDA-------- 123 8************9766.***************.66666666665..55777777777777777744555555555555........ PP Methyltransf_12 78 hl........kdirealdniyklLkpgGr 98 + ++++++++++ ++Lk G tr|H3BQF6|H3BQF6_HUMAN 124 -IslnpdnaiEKRKQYVKSLSRVLKVKGF 151 .5544444448888999999999987775 PP >> tr|H7C1L4|H7C1L4_HUMAN Methyltransferase-like protein 6 (Fragment) OS=Homo sapiens GN=METTL6 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.6 0.1 8.3e-09 4.4e-06 50 96 .. 3 51 .. 1 52 [. 0.93 Alignments for each domain: == domain 1 score: 29.6 bits; conditional E-value: 8.3e-09 Methyltransf_12 50 nvnlealdlldldggssfDvvvasnvlhhl..kdirealdniyklLkpg 96 +++l + dlld+ +++s+Dvv +++vl+++ ++++ +l+niyk+Lkpg tr|H7C1L4|H7C1L4_HUMAN 3 QCDLTKDDLLDHVPPESVDVVMLIFVLSAVhpDKMHLVLQNIYKVLKPG 51 678888999999999****************9999*************8 PP >> sp|Q5JPI9|MET10_HUMAN Methyltransferase-like protein 10 OS=Homo sapiens GN=METTL10 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.0 0.0 1.2e-08 6.5e-06 1 98 [. 84 186 .. 84 187 .. 0.73 Alignments for each domain: == domain 1 score: 29.0 bits; conditional E-value: 1.2e-08 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg..........ssfDvvvasnvlhh 78 L+iG+G+G +l +l++ +++tg+D+spsai + + + ++e+ +n++l+++d l+l + ++fD+ sp|Q5JPI9|MET10_HUMAN 84 LDIGTGNGVFLVELAKF-GFSNITGIDYSPSAI-QLSGSIIEKEG--LSNIKLKVEDFLNLSTQlsgfhicidkGTFDA--------- 158 8************9766.***************.66666666665..55777777777777777744555555555555......... PP Methyltransf_12 79 l........kdirealdniyklLkpgGr 98 + ++++++++++ ++Lk G sp|Q5JPI9|MET10_HUMAN 159 IslnpdnaiEKRKQYVKSLSRVLKVKGF 186 5544444448888999999999987775 PP >> tr|H7C2C8|H7C2C8_HUMAN Methyltransferase-like protein 2B (Fragment) OS=Homo sapiens GN=METTL2B PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.4 0.0 9.6e-09 5e-06 1 79 [. 8 91 .. 8 101 .. 0.83 Alignments for each domain: == domain 1 score: 29.4 bits; conditional E-value: 9.6e-09 Methyltransf_12 1 LeiGcGtGsllrallekl..pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg...ssfDvvvasnvlhhl 79 Le+GcG+G++++++l+ + p++ ++++D+s+ aie + l++ + ++ + + +++++ s ++++ +v+h+l tr|H7C2C8|H7C2C8_HUMAN 8 LEVGCGVGNTVFPILQTNndPGLFVYCCDFSSTAIELVQFTLSHCTDVISVHILKVCGNPASSKPTsavSPPPYAHLVSVCHAL 91 8******************9***************9999999998888877777777777777776777777777777777776 PP >> sp|Q9H825-2|METL8_HUMAN Isoform 2 of Methyltransferase-like protein 8 OS=Homo sapiens GN=METTL8 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.5 0.0 1.6e-07 8.2e-05 1 81 [. 151 236 .. 151 241 .] 0.75 Alignments for each domain: == domain 1 score: 25.5 bits; conditional E-value: 1.6e-07 Methyltransf_12 1 LeiGcGtGsllrallekl...pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg..ssfDvvvasnvlhhl.k 80 Le+GcG G+ ++++l+ l p++ ++++D+ + a+e k + + r +++++v+ +++d++ + + Dv+++ +vl+ + + sp|Q9H825-2|METL8_HUMAN 151 LEVGCGAGNSVFPILNTLensPESFLYCCDFASGAVELVKSHSSYRATQCFAFVH-DVCDDGLPYPFpdGILDVILLVFVLSSIhP 235 8*******************9999999*********5555554444444444444.44444433333799***********99854 PP Methyltransf_12 81 d 81 d sp|Q9H825-2|METL8_HUMAN 236 D 236 4 PP >> tr|K7EP06|K7EP06_HUMAN mRNA cap guanine-N7 methyltransferase OS=Homo sapiens GN=RNMT PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.0 0.0 5.1e-08 2.7e-05 1 99 [] 24 136 .. 24 136 .. 0.95 Alignments for each domain: == domain 1 score: 27.0 bits; conditional E-value: 5.1e-08 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg...........ssfDvvvasnvl 76 L++GcG G l ++ + + +++++Di ++++ +++ + +n++ +++ + a+ + + ++ fD+ + +v+ tr|K7EP06|K7EP06_HUMAN 24 LDLGCGKGGDLLKWKKG-RINKLVCTDIADVSVKQCQQRYEDMKNRRDSEYIFSAEFITADSSKellidkfrdpqMCFDICSCQFVC 109 8*************888.788899****************************9999988888779*********99*********** PP Methyltransf_12 77 hhl....kdirealdniyklLkpgGrl 99 h+ ++ + +l+n+ + L+pgG + tr|K7EP06|K7EP06_HUMAN 110 HYSfesyEQADMMLRNACERLSPGGYF 136 *************************75 PP >> tr|S4R338|S4R338_HUMAN N-terminal Xaa-Pro-Lys N-methyltransferase 1 OS=Homo sapiens GN=NTMT1 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.7 0.0 6.3e-08 3.3e-05 26 99 .] 2 75 .. 1 75 [. 0.80 Alignments for each domain: == domain 1 score: 26.7 bits; conditional E-value: 6.3e-08 Methyltransf_12 26 vDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhl..kdirealdniyklLkpgGrl 99 vDi ++++ +ak+ l +++++ n+ l+++ +++s+Dv+++ v+ hl ++++e+l++++ L+p+G++ tr|S4R338|S4R338_HUMAN 2 VDITEDFLVQAKTYLGEEGKRV-RNYFCCGLQDFTP-EPDSYDVIWIQWVIGHLtdQHLAEFLRRCKGSLRPNGII 75 8*******99999999988644.3333333443444.347**************999999**************85 PP >> sp|Q9H825|METL8_HUMAN Methyltransferase-like protein 8 OS=Homo sapiens GN=METTL8 PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.9 0.0 2.3e-07 0.00012 1 81 [. 201 286 .. 201 291 .] 0.75 Alignments for each domain: == domain 1 score: 24.9 bits; conditional E-value: 2.3e-07 Methyltransf_12 1 LeiGcGtGsllrallekl...pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg..ssfDvvvasnvlhhl.kd 81 Le+GcG G+ ++++l+ l p++ ++++D+ + a+e k + + r +++++v+ +++d++ + + Dv+++ +vl+ + +d sp|Q9H825|METL8_HUMAN 201 LEVGCGAGNSVFPILNTLensPESFLYCCDFASGAVELVKSHSSYRATQCFAFVH-DVCDDGLPYPFpdGILDVILLVFVLSSIhPD 286 8*******************9999999*********5555554444444444444.44444433333799***********998544 PP >> sp|O43148|MCES_HUMAN mRNA cap guanine-N7 methyltransferase OS=Homo sapiens GN=RNMT PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.8 0.0 1.3e-07 6.8e-05 1 99 [] 202 314 .. 202 314 .. 0.95 Alignments for each domain: == domain 1 score: 25.8 bits; conditional E-value: 1.3e-07 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg...........ssfDvvvasnvlhh 78 L++GcG G l ++ + + +++++Di ++++ +++ + +n++ +++ + a+ + + ++ fD+ + +v+h+ sp|O43148|MCES_HUMAN 202 LDLGCGKGGDLLKWKKG-RINKLVCTDIADVSVKQCQQRYEDMKNRRDSEYIFSAEFITADSSKellidkfrdpqMCFDICSCQFVCHY 289 8*************888.788899****************************9999988888779*********99************* PP Methyltransf_12 79 l....kdirealdniyklLkpgGrl 99 ++ + +l+n+ + L+pgG + sp|O43148|MCES_HUMAN 290 SfesyEQADMMLRNACERLSPGGYF 314 ***********************75 PP >> sp|P46597-3|ASMT_HUMAN Isoform 3 of Acetylserotonin O-methyltransferase OS=Homo sapiens GN=ASMT # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.9 0.0 1.2e-07 6.2e-05 5 98 .. 216 306 .. 214 307 .. 0.90 Alignments for each domain: == domain 1 score: 25.9 bits; conditional E-value: 1.2e-07 Methyltransf_12 5 cGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhl..kdirealdni 89 +G G+l++++ p++++t+ Di + + ak++++++e+ +++++++ d ++++ + D+ +++ vlh + + +l++i sp|P46597-3|ASMT_HUMAN 216 GGAGALAKECMSLYPGCKITVFDIPEVVW-TAKQHFSFQEE---EQIDFQEGDFFKDPLP-EADLYILARVLHDWadGKCSHLLERI 297 6999******9999**************9.********997...7888888887777776.**************777777****** PP Methyltransf_12 90 yklLkpgGr 98 y+ +kpgG sp|P46597-3|ASMT_HUMAN 298 YHTCKPGGG 306 *******96 PP >> sp|O43148-2|MCES_HUMAN Isoform 2 of mRNA cap guanine-N7 methyltransferase OS=Homo sapiens GN=RNMT # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.6 0.0 1.4e-07 7.5e-05 1 99 [] 202 314 .. 202 314 .. 0.95 Alignments for each domain: == domain 1 score: 25.6 bits; conditional E-value: 1.4e-07 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg...........ssfDvvvasnvl 76 L++GcG G l ++ + + +++++Di ++++ +++ + +n++ +++ + a+ + + ++ fD+ + +v+ sp|O43148-2|MCES_HUMAN 202 LDLGCGKGGDLLKWKKG-RINKLVCTDIADVSVKQCQQRYEDMKNRRDSEYIFSAEFITADSSKellidkfrdpqMCFDICSCQFVC 287 8*************888.788899****************************9999988888779*********99*********** PP Methyltransf_12 77 hhl....kdirealdniyklLkpgGrl 99 h+ ++ + +l+n+ + L+pgG + sp|O43148-2|MCES_HUMAN 288 HYSfesyEQADMMLRNACERLSPGGYF 314 *************************75 PP >> tr|H7C552|H7C552_HUMAN Methyltransferase-like protein 2B (Fragment) OS=Homo sapiens GN=METTL2B PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.8 0.0 1.2e-07 6.4e-05 64 98 .. 10 51 .. 2 52 .. 0.84 Alignments for each domain: == domain 1 score: 25.8 bits; conditional E-value: 1.2e-07 Methyltransf_12 64 g.....ssfDvvvasnvlhhl..kdirealdniyklLkpgGr 98 +s D++++++vl+++ +++++a++++ +lLkpgG+ tr|H7C552|H7C552_HUMAN 10 SypvpkGSLDIIILIFVLSAVvpDKMQKAINRLSRLLKPGGM 51 23445589*********************************8 PP >> tr|M0R0W0|M0R0W0_HUMAN Methyltransferase-like protein 6 (Fragment) OS=Homo sapiens GN=METTL6 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.0 1.0 2e-06 0.001 43 92 .. 82 133 .. 13 135 .. 0.77 Alignments for each domain: == domain 1 score: 22.0 bits; conditional E-value: 2e-06 Methyltransf_12 43 rennnnnnvnlealdlldldggssfDvvvasnvlhhl..kdirealdniykl 92 e+ ++ +++l + dlld+ +++s+Dvv +++vl+++ ++++ +l+niyk+ tr|M0R0W0|M0R0W0_HUMAN 82 TERCKVFQCDLTKDDLLDHVPPESVDVVMLIFVLSAVhpDKMHLVLQNIYKC 133 3334444555555555555555****************99999*******96 PP >> sp|Q5VVY1|NTM1B_HUMAN Alpha N-terminal protein methyltransferase 1B OS=Homo sapiens GN=METTL11B PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.0 0.0 2.2e-07 0.00012 1 99 [] 121 218 .. 121 218 .. 0.87 Alignments for each domain: == domain 1 score: 25.0 bits; conditional E-value: 2.2e-07 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhl..kdireal 86 L+ G+G G++++++l ++ vD +s++ ++ + ++++++ ++ l+ + + +Dv+++ v hl kd+ ++l sp|Q5VVY1|NTM1B_HUMAN 121 LDCGSGIGRVSKHVLLP-VFNSVELVDMMESFL-LEAQNYLQVKGDKVESYHCYSLQEFTPPF-RRYDVIWIQWVSGHLtdKDLLAFL 205 899***********999.555555*********.77888888888888888888888665544.6**************999999*** PP Methyltransf_12 87 dniyklLkpgGrl 99 +++++ Lk +G++ sp|Q5VVY1|NTM1B_HUMAN 206 SRCRDGLKENGII 218 ***********85 PP >> sp|Q96BT7|ALKB8_HUMAN Alkylated DNA repair protein alkB homolog 8 OS=Homo sapiens GN=ALKBH8 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.2 0.0 3.8e-07 0.0002 2 98 .. 412 498 .. 411 499 .. 0.76 Alignments for each domain: == domain 1 score: 24.2 bits; conditional E-value: 3.8e-07 Methyltransf_12 2 eiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhl...kdireal 86 +iGcG+G +l e +g+D s++ ++ +e+ + ++ ++ + + +++ +s D+ +++ v+hh+ + + +al sp|Q96BT7|ALKB8_HUMAN 412 DIGCGNGKYLGINKEL----YMIGCDRSQNLVDICRER--QFQAFVCDALAVPVRS-------GSCDACISIAVIHHFataERRVAAL 486 8******998876666....777*********333333..3333344555555555.......39***************66666*** PP Methyltransf_12 87 dniyklLkpgGr 98 ++i +lL+pgG+ sp|Q96BT7|ALKB8_HUMAN 487 QEIVRLLRPGGK 498 ***********7 PP >> sp|Q96BT7-4|ALKB8_HUMAN Isoform 4 of Alkylated DNA repair protein alkB homolog 8 OS=Homo sapiens GN=ALKBH8 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.2 0.0 3.8e-07 0.0002 2 98 .. 415 501 .. 414 502 .. 0.76 Alignments for each domain: == domain 1 score: 24.2 bits; conditional E-value: 3.8e-07 Methyltransf_12 2 eiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhl...kdire 84 +iGcG+G +l e +g+D s++ ++ +e+ + ++ ++ + + +++ +s D+ +++ v+hh+ + + + sp|Q96BT7-4|ALKB8_HUMAN 415 DIGCGNGKYLGINKEL----YMIGCDRSQNLVDICRER--QFQAFVCDALAVPVRS-------GSCDACISIAVIHHFataERRVA 487 8******998876666....777*********333333..3333344555555555.......39***************66666* PP Methyltransf_12 85 aldniyklLkpgGr 98 al++i +lL+pgG+ sp|Q96BT7-4|ALKB8_HUMAN 488 ALQEIVRLLRPGGK 501 *************7 PP >> tr|H7C4Z8|H7C4Z8_HUMAN Methyltransferase-like protein 2B (Fragment) OS=Homo sapiens GN=METTL2B PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.2 0.0 3.8e-07 0.0002 1 37 [. 179 216 .. 179 233 .. 0.84 Alignments for each domain: == domain 1 score: 24.2 bits; conditional E-value: 3.8e-07 Methyltransf_12 1 LeiGcGtGsllrallekl..pdieytgvDispsaiedak 37 Le+GcG+G++++++l+ + p++ ++++D+s+ aie tr|H7C4Z8|H7C4Z8_HUMAN 179 LEVGCGVGNTVFPILQTNndPGLFVYCCDFSSTAIE-LV 216 8******************9***************3.33 PP >> sp|Q8N6F8|WBS27_HUMAN Williams-Beuren syndrome chromosomal region 27 protein OS=Homo sapiens GN=WBSCR27 PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.1 0.0 4.3e-07 0.00023 1 78 [. 72 143 .. 72 163 .. 0.79 Alignments for each domain: == domain 1 score: 24.1 bits; conditional E-value: 4.3e-07 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhh 78 L++ cGtG ++++l++ ++++gvD sp ++ ++ a ++ + ++l ++ l + +g +fD+v++ ++l+ sp|Q8N6F8|WBS27_HUMAN 72 LDVACGTGLVAAELRAP-GFLQLHGVDGSPGML---EQAQAPGLYQRLSLCTLGQEPLPSPEG--TFDAVLIVGALSD 143 8**************99.***************...333333334567789999998887666..9******999985 PP >> sp|Q7L2J0-2|MEPCE_HUMAN Isoform 2 of 7SK snRNA methylphosphate capping enzyme OS=Homo sapiens GN=MEPCE # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.5 0.0 2.3 1.2e+03 24 43 .. 2 21 .. 1 40 [. 0.86 2 ! 20.1 0.0 7.5e-06 0.004 57 99 .] 97 144 .. 75 144 .. 0.80 Alignments for each domain: == domain 1 score: 2.5 bits; conditional E-value: 2.3 Methyltransf_12 24 tgvDispsaiedakeklakr 43 +g+Di+++ i+ a++ ++++ sp|Q7L2J0-2|MEPCE_HUMAN 2 VGLDIDSRLIHSARQNIRHY 21 79********9999998876 PP == domain 2 score: 20.1 bits; conditional E-value: 7.5e-06 Methyltransf_12 57 dlldldgg..ssfDvvvasnvlhhl......kdirealdniyklLkpgGrl 99 dl + +Dvv+++++ ++ + +++++++iy++L+pgG+l sp|Q7L2J0-2|MEPCE_HUMAN 97 DLVE---AqtPEYDVVLCLSLTKWVhlnwgdEGLKRMFRRIYRHLRPGGIL 144 2222...13369*************************************87 PP >> sp|Q9Y5R4|HEMK1_HUMAN HemK methyltransferase family member 1 OS=Homo sapiens GN=HEMK1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.9 0.0 4.9e-07 0.00026 1 77 [. 164 245 .. 164 261 .. 0.71 Alignments for each domain: == domain 1 score: 23.9 bits; conditional E-value: 4.9e-07 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.....ssfDvvvas..nvlh 77 Le+GcG+G+++ ll +lp++++++vD ++ai ++ ++++ + +++ + +ld+ ++ + + D++v++ v+h sp|Q9Y5R4|HEMK1_HUMAN 164 LEVGCGSGAISLSLLSQLPQSRVIAVDKREAAI--SLTHENAQRLRLQDRIWIIHLDMTSERSWthlpwGPMDLIVSNppYVFH 245 8********************************..4444444444445566666666544333366777788888877555555 PP >> tr|H7C258|H7C258_HUMAN HemK methyltransferase family member 1 (Fragment) OS=Homo sapiens GN=HEMK1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.5 0.0 6.3e-07 0.00033 1 43 [. 2 44 .. 2 67 .. 0.81 Alignments for each domain: == domain 1 score: 23.5 bits; conditional E-value: 6.3e-07 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakr 43 Le+GcG+G+++ ll +lp++++++vD ++ai + e +++ tr|H7C258|H7C258_HUMAN 2 LEVGCGSGAISLSLLSQLPQSRVIAVDKREAAISLTHENAQSY 44 8********************************4444443333 PP >> tr|F8WD67|F8WD67_HUMAN Uncharacterized methyltransferase WBSCR22 OS=Homo sapiens GN=WBSCR22 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.4 0.1 1.4e-06 0.00073 1 37 [. 58 92 .. 58 100 .. 0.84 Alignments for each domain: == domain 1 score: 22.4 bits; conditional E-value: 1.4e-06 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedak 37 L+iGcGtG ++l ++ + +g+Disp++++ a tr|F8WD67|F8WD67_HUMAN 58 LDIGCGTGLSGSYLSDE--GHYWVGLDISPAMLDEAV 92 8*************999..66666*********6654 PP >> sp|O43709-2|WBS22_HUMAN Isoform 2 of Uncharacterized methyltransferase WBSCR22 OS=Homo sapiens GN=WBSCR22 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.1 0.0 1.8e-06 0.00092 1 39 [. 58 94 .. 58 142 .. 0.83 Alignments for each domain: == domain 1 score: 22.1 bits; conditional E-value: 1.8e-06 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakek 39 L+iGcGtG ++l ++ + +g+Disp++++ a + sp|O43709-2|WBS22_HUMAN 58 LDIGCGTGLSGSYLSDE--GHYWVGLDISPAMLDEAVDR 94 8*************999..66666*********655444 PP >> tr|E7EMN2|E7EMN2_HUMAN Methyltransferase-like protein 5 OS=Homo sapiens GN=METTL5 PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.2 0.0 1.7e-06 0.0009 2 73 .. 57 126 .. 56 131 .. 0.92 Alignments for each domain: == domain 1 score: 22.2 bits; conditional E-value: 1.7e-06 Methyltransf_12 2 eiGcGtGsllralleklpdieyt.gvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvas 73 ++GcG G l+ ++ ++ ++ g Di+++a+e + + e n + v+ +++ l+++ ++ sfD+v+++ tr|E7EMN2|E7EMN2_HUMAN 57 DLGCGCGVLSIGTAML--GAGLCvGFDIDEDALEIFNRNAEEFELTNIDMVQCDVCLLSNRMSK-SFDTVIMN 126 89**************..888877*********9999999999999999999999999888886.******97 PP >> tr|B8ZZE3|B8ZZE3_HUMAN Methyltransferase like 5, isoform CRA_b OS=Homo sapiens GN=METTL5 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.6 0.0 2.6e-06 0.0014 2 73 .. 57 126 .. 56 131 .. 0.92 Alignments for each domain: == domain 1 score: 21.6 bits; conditional E-value: 2.6e-06 Methyltransf_12 2 eiGcGtGsllralleklpdieyt.gvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvas 73 ++GcG G l+ ++ ++ ++ g Di+++a+e + + e n + v+ +++ l+++ ++ sfD+v+++ tr|B8ZZE3|B8ZZE3_HUMAN 57 DLGCGCGVLSIGTAML--GAGLCvGFDIDEDALEIFNRNAEEFELTNIDMVQCDVCLLSNRMSK-SFDTVIMN 126 89**************..888877*********9999999999999999999999999888886.******97 PP >> sp|O43709|WBS22_HUMAN Uncharacterized methyltransferase WBSCR22 OS=Homo sapiens GN=WBSCR22 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.5 0.0 2.8e-06 0.0015 1 38 [. 58 93 .. 58 140 .. 0.84 Alignments for each domain: == domain 1 score: 21.5 bits; conditional E-value: 2.8e-06 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedake 38 L+iGcGtG ++l ++ + +g+Disp++++ a sp|O43709|WBS22_HUMAN 58 LDIGCGTGLSGSYLSDE--GHYWVGLDISPAMLDEAVD 93 8*************999..66666*********65544 PP >> sp|Q9NRN9|METL5_HUMAN Methyltransferase-like protein 5 OS=Homo sapiens GN=METTL5 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.4 0.0 2.9e-06 0.0015 2 73 .. 57 126 .. 56 131 .. 0.92 Alignments for each domain: == domain 1 score: 21.4 bits; conditional E-value: 2.9e-06 Methyltransf_12 2 eiGcGtGsllralleklpdieyt.gvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvas 73 ++GcG G l+ ++ ++ ++ g Di+++a+e + + e n + v+ +++ l+++ ++ sfD+v+++ sp|Q9NRN9|METL5_HUMAN 57 DLGCGCGVLSIGTAML--GAGLCvGFDIDEDALEIFNRNAEEFELTNIDMVQCDVCLLSNRMSK-SFDTVIMN 126 89**************..888877*********9999999999999999999999999888886.******97 PP >> tr|C9K060|C9K060_HUMAN Uncharacterized methyltransferase WBSCR22 OS=Homo sapiens GN=WBSCR22 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.3 0.0 3.1e-06 0.0016 1 38 [. 58 93 .. 58 140 .. 0.84 Alignments for each domain: == domain 1 score: 21.3 bits; conditional E-value: 3.1e-06 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedake 38 L+iGcGtG ++l ++ + +g+Disp++++ a tr|C9K060|C9K060_HUMAN 58 LDIGCGTGLSGSYLSDE--GHYWVGLDISPAMLDEAVD 93 8*************999..66666*********65544 PP >> tr|B8ZZC8|B8ZZC8_HUMAN Methyltransferase-like protein 5 OS=Homo sapiens GN=METTL5 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.0 0.0 4e-06 0.0021 2 73 .. 57 126 .. 56 131 .. 0.92 Alignments for each domain: == domain 1 score: 21.0 bits; conditional E-value: 4e-06 Methyltransf_12 2 eiGcGtGsllralleklpdieyt.gvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvas 73 ++GcG G l+ ++ ++ ++ g Di+++a+e + + e n + v+ +++ l+++ ++ sfD+v+++ tr|B8ZZC8|B8ZZC8_HUMAN 57 DLGCGCGVLSIGTAML--GAGLCvGFDIDEDALEIFNRNAEEFELTNIDMVQCDVCLLSNRMSK-SFDTVIMN 126 89**************..888877*********9999999999999999999999999888886.******97 PP >> sp|O60344|ECE2_HUMAN Endothelin-converting enzyme 2 OS=Homo sapiens GN=ECE2 PE=1 SV=4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.4 0.0 6.1e-06 0.0032 1 80 [. 63 141 .. 63 162 .. 0.83 Alignments for each domain: == domain 1 score: 20.4 bits; conditional E-value: 6.1e-06 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhl....k 80 L +GcG+++l+ +l ++t vD+s+ ++++ ++++a+ + +++ +++++ld + +sfDvv+ ++l +l + sp|O60344|ECE2_HUMAN 63 LVLGCGNSALSYELFLG-GFPNVTSVDYSSVVVAAMQARHAHVPQLRWETMDVRKLDFPS----ASFDVVLEKGTLDALlageR 141 569**********9888.99*************999999999998888888888888654....5**********999877663 PP >> tr|F8WD87|F8WD87_HUMAN Uncharacterized methyltransferase WBSCR22 OS=Homo sapiens GN=WBSCR22 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.2 0.2 6.8e-06 0.0036 1 33 [. 58 88 .. 58 91 .. 0.91 Alignments for each domain: == domain 1 score: 20.2 bits; conditional E-value: 6.8e-06 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsai 33 L+iGcGtG ++l ++ + +g+Disp+++ tr|F8WD87|F8WD87_HUMAN 58 LDIGCGTGLSGSYLSDE--GHYWVGLDISPAML 88 8*************999..66666*******98 PP >> sp|Q9BTF0|THUM2_HUMAN THUMP domain-containing protein 2 OS=Homo sapiens GN=THUMPD2 PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.4 0.0 1.3e-05 0.0066 5 98 .. 307 403 .. 303 404 .. 0.81 Alignments for each domain: == domain 1 score: 19.4 bits; conditional E-value: 1.3e-05 Methyltransf_12 5 cGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.ssfDvvvasnvlhhl....kdireald 87 cG G++l + +++ pd+ y+g D+s s++ + l++ + ++++l ++++++l+ + +s+D++++ + kdi+++l+ sp|Q9BTF0|THUM2_HUMAN 307 CGLGTILLEAAKEWPDVYYVGADVSDSQLLGTWDNLKAAGL--EDKIELLKISVIELPLPsESVDIIISDIPFGKKfklgKDIKSILQ 392 *****************************666666666665..3488888888887777789******664444444677******** PP Methyltransf_12 88 niyklLkpgGr 98 ++ ++L gG sp|Q9BTF0|THUM2_HUMAN 393 EMERVLHVGGT 403 ********997 PP >> tr|E9PCQ7|E9PCQ7_HUMAN Uncharacterized methyltransferase WBSCR22 OS=Homo sapiens GN=WBSCR22 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.1 0.1 7.3e-06 0.0038 1 33 [. 58 88 .. 58 92 .. 0.89 Alignments for each domain: == domain 1 score: 20.1 bits; conditional E-value: 7.3e-06 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsai 33 L+iGcGtG ++l ++ + +g+Disp+++ tr|E9PCQ7|E9PCQ7_HUMAN 58 LDIGCGTGLSGSYLSDE--GHYWVGLDISPAML 88 8*************999..66666********9 PP >> tr|B3KR83|B3KR83_HUMAN Uncharacterized methyltransferase WBSCR22 OS=Homo sapiens GN=WBSCR22 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.7 0.2 1e-05 0.0053 1 33 [. 81 111 .. 81 114 .. 0.91 Alignments for each domain: == domain 1 score: 19.7 bits; conditional E-value: 1e-05 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsai 33 L+iGcGtG ++l ++ + +g+Disp+++ tr|B3KR83|B3KR83_HUMAN 81 LDIGCGTGLSGSYLSDE--GHYWVGLDISPAML 111 8*************999..66666*******98 PP >> sp|O60678-2|ANM3_HUMAN Isoform 2 of Protein arginine N-methyltransferase 3 OS=Homo sapiens GN=PRMT3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.8 0.0 1.9e-05 0.0099 1 97 [. 198 294 .. 198 296 .. 0.66 Alignments for each domain: == domain 1 score: 18.8 bits; conditional E-value: 1.9e-05 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.ssfDvvv...asnvlhhlkdir 83 L++GcGtG l++ +++ +++gvD s+ +a ++ ++ + ++l + ++++ + + +++Dv++ + +l ++ sp|O60678-2|ANM3_HUMAN 198 LDVGCGTGILSMFAAKA-GAKKVLGVDQSEILY-QAMDIIRLNKL--EDTITLIKGKIEEVHLPvEKVDVIIsewMGYFLLFESMLD 280 8*******999999999.999999******999.44444444443..2355555555555555568999998443333333335666 PP Methyltransf_12 84 ealdniyklLkpgG 97 ++l k L++gG sp|O60678-2|ANM3_HUMAN 281 SVLYAKNKYLAKGG 294 77777777777776 PP >> sp|O60678|ANM3_HUMAN Protein arginine N-methyltransferase 3 OS=Homo sapiens GN=PRMT3 PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.5 0.0 2.3e-05 0.012 1 97 [. 260 356 .. 260 358 .. 0.66 Alignments for each domain: == domain 1 score: 18.5 bits; conditional E-value: 2.3e-05 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.ssfDvvv...asnvlhhlkdirea 85 L++GcGtG l++ +++ +++gvD s+ +a ++ ++ + ++l + ++++ + + +++Dv++ + +l ++++ sp|O60678|ANM3_HUMAN 260 LDVGCGTGILSMFAAKA-GAKKVLGVDQSEILY-QAMDIIRLNKL--EDTITLIKGKIEEVHLPvEKVDVIIsewMGYFLLFESMLDSV 344 8*******999999999.999999******999.44444444443..235555555555555556899999844333333333566677 PP Methyltransf_12 86 ldniyklLkpgG 97 l k L++gG sp|O60678|ANM3_HUMAN 345 LYAKNKYLAKGG 356 777777777776 PP >> sp|A8MUP2|MET12_HUMAN Methyltransferase-like protein 12, mitochondrial OS=Homo sapiens GN=METTL12 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.9 0.0 1.8e-05 0.0092 1 47 [. 80 127 .. 80 194 .. 0.64 Alignments for each domain: == domain 1 score: 18.9 bits; conditional E-value: 1.8e-05 Methyltransf_12 1 LeiGcGtGsllrallekl.pdieytgvDispsaiedakeklakrennn 47 L++GcGt+sl l k ++++++gvD+sp a+++ l ++ sp|A8MUP2|MET12_HUMAN 80 LDVGCGTSSLCTGLYTKSpHPVDVLGVDFSPVAVAHMNSLLEGGPGQT 127 8****************988**************66665555555444 PP >> tr|D6RCL3|D6RCL3_HUMAN Probable dimethyladenosine transferase OS=Homo sapiens GN=DIMT1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.5 0.0 1.1e-05 0.006 1 72 [. 61 127 .. 61 137 .. 0.88 Alignments for each domain: == domain 1 score: 19.5 bits; conditional E-value: 1.1e-05 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvva 72 Le+G GtG+++ +llek ++++++++p+ + a+++ + ++ ++++++ + d+l++d + fD+ va tr|D6RCL3|D6RCL3_HUMAN 61 LEVGPGTGNMTVKLLEK--AKKVVACELDPRLV--AELHKRVQGTPVASKLQVLVGDVLKTDLP-FFDTCVA 127 8****************..**************..77777777777899999999999999988.7887776 PP >> tr|B4DP72|B4DP72_HUMAN 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial OS=Homo sapiens GN=COQ5 PE=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.2 0.0 3e-05 0.016 58 99 .] 129 168 .. 110 168 .. 0.82 Alignments for each domain: == domain 1 score: 18.2 bits; conditional E-value: 3e-05 Methyltransf_12 58 lldldgg.ssfDvvvasnvlhhlkdirealdniyklLkpgGrl 99 l ++fD+ ++++ + ++ +i++al++++++LkpgGr+ tr|B4DP72|B4DP72_HUMAN 129 LPF---DdDKFDIYTIAFGIRNVTHIDQALQEAHRVLKPGGRF 168 222...2469*******************************96 PP >> sp|Q9H7H0-3|MET17_HUMAN Isoform 3 of Methyltransferase-like protein 17, mitochondrial OS=Homo sapiens GN=METTL17 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.6 0.0 9.1e-05 0.048 1 89 [. 190 284 .. 190 291 .. 0.69 Alignments for each domain: == domain 1 score: 16.6 bits; conditional E-value: 9.1e-05 Methyltransf_12 1 LeiGcGtGsllrallekl..pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg....ssfDvvvasnvlhhl. 79 +++G+GtGs++ a + ey +vD s++++ a++ l+ + ++ + + + l + +fDvvv+++ l+ l sp|Q9H7H0-3|MET17_HUMAN 190 MDFGSGTGSVTWAAHSIWgqSLREYMCVDRSAAMLVLAEKLLKG-GSESGEPYIPGVFFRQFL--PvspkVQFDVVVSAFSLSELp 272 69********9998555588899************555544444.444444433332222211..123459************998 PP Methyltransf_12 80 ..kdirealdni 89 +d+ e+++ + sp|Q9H7H0-3|MET17_HUMAN 273 skADRTEVVQTL 284 877777777665 PP >> sp|Q5TEU4-2|NDUF5_HUMAN Isoform 2 of NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 5 OS=Homo sa # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.6 0.0 0.25 1.3e+02 1 17 [. 94 110 .. 94 124 .. 0.88 2 ! 11.2 0.0 0.0044 2.3 75 99 .] 132 156 .. 130 156 .. 0.94 Alignments for each domain: == domain 1 score: 5.6 bits; conditional E-value: 0.25 Methyltransf_12 1 LeiGcGtGsllrallek 17 L++GcG G ++++l + sp|Q5TEU4-2|NDUF5_HUMAN 94 LDLGCGRGYIAQYLNKL 110 8***********99765 PP == domain 2 score: 11.2 bits; conditional E-value: 0.0044 Methyltransf_12 75 vlhhlkdirealdniyklLkpgGrl 99 +lh+++d+ +al++i+ Lkp+G++ sp|Q5TEU4-2|NDUF5_HUMAN 132 CLHWVNDLPRALEQIHYILKPDGVF 156 69*********************86 PP >> sp|Q5T8I9|HENMT_HUMAN Small RNA 2'-O-methyltransferase OS=Homo sapiens GN=HENMT1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.8 0.0 3.9e-05 0.021 2 91 .. 53 151 .. 52 156 .. 0.72 Alignments for each domain: == domain 1 score: 17.8 bits; conditional E-value: 3.9e-05 Methyltransf_12 2 eiGcGtGsllralleklpdieyt.gvDispsaiedakeklakrennnnnnvnlealdlldldgg..........ssfDvvvasnvlhh 78 ++GcG+ sllr l + p ie++ gvDi+++ + + + + + ++++ ++l+l + fD+++++++++h sp|Q5T8I9|HENMT_HUMAN 53 DLGCGDTSLLRLLKVN-PCIELLvGVDINEDKL---RWRGDSLAPFLGDFLKPRDLNLTITLYHgsvverdsrlLGFDLITCIELIEH 136 89********988666.****999*********...444444444444444444444443333355888888899************* PP Methyltransf_12 79 l..kdirealdniyk 91 l d++++ + + sp|Q5T8I9|HENMT_HUMAN 137 LdsGDLARFPEVVFG 151 *87777666555555 PP >> sp|Q7Z5W3|BN3D2_HUMAN Pre-miRNA 5'-monophosphate methyltransferase OS=Homo sapiens GN=BCDIN3D PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.5 0.0 0.0002 0.11 1 47 [. 71 130 .. 71 212 .. 0.83 2 ? 1.4 0.0 5.1 2.7e+03 16 52 .. 184 222 .. 175 251 .. 0.77 Alignments for each domain: == domain 1 score: 15.5 bits; conditional E-value: 0.0002 Methyltransf_12 1 LeiGcGtGsllrallekl.............pdieytgvDispsaiedakeklakrennn 47 L++Gc++G+l+ al +++ ++ +++++Di+p +++a+++ + ++ sp|Q7Z5W3|BN3D2_HUMAN 71 LDVGCNSGDLSVALYKHFlslpdgetcsdasREFRLLCCDIDPVLVKRAEKECPFPDALT 130 8*****************************99**************88887766666544 PP == domain 2 score: 1.4 bits; conditional E-value: 5.1 Methyltransf_12 16 ekl.pdieytgvDispsai.edakeklakrennnnnnvn 52 ++l + ++y+ v+++p + +a+++l+k + +++++++ sp|Q7Z5W3|BN3D2_HUMAN 184 AHLsSLCHYLLVEPQPWKCyRAAARRLRKLGLHDFDHFH 222 444356888888888888888888888888887777665 PP >> sp|Q9UNQ2|DIM1_HUMAN Probable dimethyladenosine transferase OS=Homo sapiens GN=DIMT1 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 17.5 0.0 4.9e-05 0.026 1 72 [. 61 127 .. 61 135 .. 0.87 Alignments for each domain: == domain 1 score: 17.5 bits; conditional E-value: 4.9e-05 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvva 72 Le+G GtG+++ +llek ++++++++p+ + a+++ + ++ ++++++ + d+l++d + fD+ va sp|Q9UNQ2|DIM1_HUMAN 61 LEVGPGTGNMTVKLLEK--AKKVVACELDPRLV--AELHKRVQGTPVASKLQVLVGDVLKTDLP-FFDTCVA 127 8****************..**************..77777777777889999999999999887.7777766 PP >> tr|K7EQA8|K7EQA8_HUMAN Histone-arginine methyltransferase CARM1 (Fragment) OS=Homo sapiens GN=CARM1 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 17.3 0.0 5.7e-05 0.03 1 98 [. 148 243 .. 148 244 .. 0.78 Alignments for each domain: == domain 1 score: 17.3 bits; conditional E-value: 5.7e-05 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhl..kdirea 85 L++GcG+G l++ +++ ++++v+ s+ a ++e l k +nn ++++ + ++++ ++++D++++ l + + e+ tr|K7EQA8|K7EQA8_HUMAN 148 LDVGCGSGILSFFAAQA-GARKIYAVEASTMAQ--HAEVLVK-SNNLTDRIVVIPGKVEEVSLPEQVDIIISEPMGYMLfnERMLES 230 8*******999999999.888999******999..3333333.3345678888888888888889***9986644444466999999 PP Methyltransf_12 86 ldniyklLkpgGr 98 +++k Lkp G tr|K7EQA8|K7EQA8_HUMAN 231 YLHAKKYLKPSGN 243 9999999999985 PP >> sp|Q9H7H0-2|MET17_HUMAN Isoform 2 of Methyltransferase-like protein 17, mitochondrial OS=Homo sapiens GN=METTL17 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 16.8 0.0 8.1e-05 0.043 1 89 [. 190 284 .. 190 291 .. 0.69 Alignments for each domain: == domain 1 score: 16.8 bits; conditional E-value: 8.1e-05 Methyltransf_12 1 LeiGcGtGsllrallekl..pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg....ssfDvvvasnvlhhl. 79 +++G+GtGs++ a + ey +vD s++++ a++ l+ + ++ + + + l + +fDvvv+++ l+ l sp|Q9H7H0-2|MET17_HUMAN 190 MDFGSGTGSVTWAAHSIWgqSLREYMCVDRSAAMLVLAEKLLKG-GSESGEPYIPGVFFRQFL--PvspkVQFDVVVSAFSLSELp 272 69********9998555588899************555544444.444444433332222211..123459************998 PP Methyltransf_12 80 ..kdirealdni 89 +d+ e+++ + sp|Q9H7H0-2|MET17_HUMAN 273 skADRTEVVQTL 284 877777777665 PP >> sp|Q9H7H0|MET17_HUMAN Methyltransferase-like protein 17, mitochondrial OS=Homo sapiens GN=METTL17 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 16.7 0.0 8.4e-05 0.044 1 89 [. 190 284 .. 190 291 .. 0.69 Alignments for each domain: == domain 1 score: 16.7 bits; conditional E-value: 8.4e-05 Methyltransf_12 1 LeiGcGtGsllrallekl..pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg....ssfDvvvasnvlhhl... 79 +++G+GtGs++ a + ey +vD s++++ a++ l+ + ++ + + + l + +fDvvv+++ l+ l sp|Q9H7H0|MET17_HUMAN 190 MDFGSGTGSVTWAAHSIWgqSLREYMCVDRSAAMLVLAEKLLKG-GSESGEPYIPGVFFRQFL--PvspkVQFDVVVSAFSLSELpsk 274 69********9998555588899************555544444.444444433332222211..123459************99887 PP Methyltransf_12 80 kdirealdni 89 +d+ e+++ + sp|Q9H7H0|MET17_HUMAN 275 ADRTEVVQTL 284 7777777665 PP >> tr|F8W9F3|F8W9F3_HUMAN Protein-L-isoaspartate O-methyltransferase domain-containing protein 2 OS=Homo sapiens GN=PCM # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 16.2 0.0 0.00012 0.063 1 73 [. 85 166 .. 85 187 .. 0.90 Alignments for each domain: == domain 1 score: 16.2 bits; conditional E-value: 0.00012 Methyltransf_12 1 LeiGcGtGsllrallekl.pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg........ssfDvvvas 73 L +G+GtG l++++ l p +gv++++++ie ak+kl + ++ + ++ +++ ++ + g+ s++D v++ tr|F8W9F3|F8W9F3_HUMAN 85 LNLGSGTGYLSSMVGLILgPFGVNHGVELHSDVIEYAKQKLDFFIRTSDSFDKFDFCEPSFVTGNcleispdcSQYDRVYCG 166 679***********99998899999**************************9999999999888899999999999999986 PP >> sp|O95568|MET18_HUMAN Histidine protein methyltransferase 1 homolog OS=Homo sapiens GN=METTL18 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 16.8 0.0 7.7e-05 0.041 1 99 [] 192 319 .. 192 319 .. 0.80 Alignments for each domain: == domain 1 score: 16.8 bits; conditional E-value: 7.7e-05 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsai......edakeklakrennnnnnvnlealdlldldgg.................. 64 L++GcG+G l + e+++ D+++ +i + n+ ++ e++d+ + d + sp|O95568|MET18_HUMAN 192 LDLGCGSGLLGITAFKG-GSKEIHFQDYNSMVIdevtlpN----------VVANSTLEDEENDVNEPDVKrcrkpkvtqlykcrffsg 268 8*********9999999.9**************5322221..........233334444444444433335555678888******** PP Methyltransf_12 65 ................ssfDvvvasnvlhhlkdirealdniyklLkpgGrl 99 ++D+++ s+++ + + + + + +lL+++Gr+ sp|O95568|MET18_HUMAN 269 ewsefcklvlsseklfVKYDLILTSETIYNPDYYSNLHQTFLRLLSKNGRV 319 ******************************999999999999*******85 PP >> sp|Q86X55-2|CARM1_HUMAN Isoform 2 of Histone-arginine methyltransferase CARM1 OS=Homo sapiens GN=CARM1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 17.0 0.0 7e-05 0.037 1 98 [. 189 284 .. 189 285 .. 0.78 Alignments for each domain: == domain 1 score: 17.0 bits; conditional E-value: 7e-05 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhl..kdire 84 L++GcG+G l++ +++ ++++v+ s+ a ++e l k +nn ++++ + ++++ ++++D++++ l + + e sp|Q86X55-2|CARM1_HUMAN 189 LDVGCGSGILSFFAAQA-GARKIYAVEASTMAQ--HAEVLVK-SNNLTDRIVVIPGKVEEVSLPEQVDIIISEPMGYMLfnERMLE 270 8*******999999999.888999******999..3333333.3345678888888888888889***998664444446699999 PP Methyltransf_12 85 aldniyklLkpgGr 98 + +++k Lkp G sp|Q86X55-2|CARM1_HUMAN 271 SYLHAKKYLKPSGN 284 99999999999985 PP >> sp|P40261|NNMT_HUMAN Nicotinamide N-methyltransferase OS=Homo sapiens GN=NNMT PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.0 0.0 0.00057 0.3 13 99 .] 70 193 .. 60 193 .. 0.69 Alignments for each domain: == domain 1 score: 14.0 bits; conditional E-value: 0.00057 Methyltransf_12 13 allekl.pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg..................................ss 66 ll + + e++++D+s + + + ek k+e++ +++ + + dl+g+ sp|P40261|NNMT_HUMAN 70 QLLSACeSFKEIVVTDYSDQNL-QELEKWLKKEPEAFDWSPVVTYV-CDLEGNrvkgpekeeklrqavkqvlkcdvtqsqplgavplPP 156 4444443688888888888888.44444444444444433333332.33444456678888888888888888888888888888889* PP Methyltransf_12 67 fDvvvasnvlhhl....kdirealdniyklLkpgGrl 99 D v++ +l + ++ +al+n+ +lLkpgG l sp|P40261|NNMT_HUMAN 157 ADCVLSTLCLDAAcpdlPTYCRALRNLGSLLKPGGFL 193 ************9987777779*************86 PP >> sp|Q86X55-1|CARM1_HUMAN Isoform 1 of Histone-arginine methyltransferase CARM1 OS=Homo sapiens GN=CARM1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 16.0 0.0 0.00014 0.074 1 98 [. 189 284 .. 189 285 .. 0.78 Alignments for each domain: == domain 1 score: 16.0 bits; conditional E-value: 0.00014 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhl..kdire 84 L++GcG+G l++ +++ ++++v+ s+ a ++e l k +nn ++++ + ++++ ++++D++++ l + + e sp|Q86X55-1|CARM1_HUMAN 189 LDVGCGSGILSFFAAQA-GARKIYAVEASTMAQ--HAEVLVK-SNNLTDRIVVIPGKVEEVSLPEQVDIIISEPMGYMLfnERMLE 270 8*******999999999.888999******999..3333333.3345678888888888888889***998664444446699999 PP Methyltransf_12 85 aldniyklLkpgGr 98 + +++k Lkp G sp|Q86X55-1|CARM1_HUMAN 271 SYLHAKKYLKPSGN 284 99999999999985 PP >> sp|Q9NV79-2|PCMD2_HUMAN Isoform 2 of Protein-L-isoaspartate O-methyltransferase domain-containing protein 2 OS=Homo # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.7 0.0 0.00017 0.09 1 73 [. 85 166 .. 85 186 .. 0.91 Alignments for each domain: == domain 1 score: 15.7 bits; conditional E-value: 0.00017 Methyltransf_12 1 LeiGcGtGsllrallekl.pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg........ssfDvvvas 73 L +G+GtG l++++ l p +gv++++++ie ak+kl + ++ + ++ +++ ++ + g+ s++D v++ sp|Q9NV79-2|PCMD2_HUMAN 85 LNLGSGTGYLSSMVGLILgPFGVNHGVELHSDVIEYAKQKLDFFIRTSDSFDKFDFCEPSFVTGNcleispdcSQYDRVYCG 166 679***********99998899999*************************99999999998888899999999999999886 PP >> sp|Q86X55|CARM1_HUMAN Histone-arginine methyltransferase CARM1 OS=Homo sapiens GN=CARM1 PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.9 0.0 0.00015 0.078 1 98 [. 189 284 .. 189 285 .. 0.78 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 0.00015 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhl..kdireal 86 L++GcG+G l++ +++ ++++v+ s+ a ++e l k +nn ++++ + ++++ ++++D++++ l + + e+ sp|Q86X55|CARM1_HUMAN 189 LDVGCGSGILSFFAAQA-GARKIYAVEASTMAQ--HAEVLVK-SNNLTDRIVVIPGKVEEVSLPEQVDIIISEPMGYMLfnERMLESY 272 8*******999999999.888999******999..3333333.3345678888888888888889***99866444444669999999 PP Methyltransf_12 87 dniyklLkpgGr 98 +++k Lkp G sp|Q86X55|CARM1_HUMAN 273 LHAKKYLKPSGN 284 999999999985 PP >> sp|Q9NV79|PCMD2_HUMAN Protein-L-isoaspartate O-methyltransferase domain-containing protein 2 OS=Homo sapiens GN=PCMT # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.6 0.0 0.00019 0.1 1 73 [. 85 166 .. 85 187 .. 0.90 Alignments for each domain: == domain 1 score: 15.6 bits; conditional E-value: 0.00019 Methyltransf_12 1 LeiGcGtGsllrallekl.pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg........ssfDvvvas 73 L +G+GtG l++++ l p +gv++++++ie ak+kl + ++ + ++ +++ ++ + g+ s++D v++ sp|Q9NV79|PCMD2_HUMAN 85 LNLGSGTGYLSSMVGLILgPFGVNHGVELHSDVIEYAKQKLDFFIRTSDSFDKFDFCEPSFVTGNcleispdcSQYDRVYCG 166 679***********99998899999*************************99999999998888899999999999999886 PP >> sp|Q9Y5N5|HEMK2_HUMAN HemK methyltransferase family member 2 OS=Homo sapiens GN=N6AMT1 PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 16.6 0.0 9.1e-05 0.048 1 47 [. 50 96 .. 50 123 .. 0.74 Alignments for each domain: == domain 1 score: 16.6 bits; conditional E-value: 9.1e-05 Methyltransf_12 1 LeiGcGtGsllrallekl.pdieytgvDispsaiedakeklakrennn 47 Le+G+G+G +++ l+ + p++ y ++Di+p+a + +++a+ ++ + sp|Q9Y5N5|HEMK2_HUMAN 50 LEVGSGSGVVSAFLASMIgPQALYMCTDINPEAA-ACTLETARCNKVH 96 8*****************9999999********9.5555555444433 PP >> sp|O43159|RRP8_HUMAN Ribosomal RNA-processing protein 8 OS=Homo sapiens GN=RRP8 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.4 0.0 0.00089 0.47 64 99 .] 341 388 .. 313 388 .. 0.72 Alignments for each domain: == domain 1 score: 13.4 bits; conditional E-value: 0.00089 Methyltransf_12 64 g.............ssfDvvvasnvlhhlkdirealdniyklLkpgGrl 99 + +s+Dv+v + l +ir++l+++ ++LkpgG l sp|O43159|RRP8_HUMAN 341 RvtvcdmaqvpledESVDVAVFCLSLMG-TNIRDFLEEANRVLKPGGLL 388 3333444445555679999887777777.5*****************86 PP >> sp|Q96GJ1-3|TRM2_HUMAN Isoform 3 of tRNA (uracil(54)-C(5))-methyltransferase homolog OS=Homo sapiens GN=TRMT2B # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 16.3 0.0 0.00012 0.061 1 59 [. 304 360 .. 304 398 .. 0.88 Alignments for each domain: == domain 1 score: 16.3 bits; conditional E-value: 0.00012 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdll 59 L+i cGtG + l+++ +++++g+++ ++a+eda+ a+++ n ++ + +a+++l sp|Q96GJ1-3|TRM2_HUMAN 304 LDICCGTGVIGLSLAQH--TSRVLGIELLEQAVEDARWTAAFNGITNSEFHTGQAEKIL 360 89***************..************************9999888888877664 PP >> tr|F2Z384|F2Z384_HUMAN tRNA (uracil(54)-C(5))-methyltransferase homolog OS=Homo sapiens GN=TRMT2B PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 16.1 0.0 0.00013 0.069 1 59 [. 349 405 .. 349 443 .. 0.88 Alignments for each domain: == domain 1 score: 16.1 bits; conditional E-value: 0.00013 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdll 59 L+i cGtG + l+++ +++++g+++ ++a+eda+ a+++ n ++ + +a+++l tr|F2Z384|F2Z384_HUMAN 349 LDICCGTGVIGLSLAQH--TSRVLGIELLEQAVEDARWTAAFNGITNSEFHTGQAEKIL 405 89***************..************************9999888888877664 PP >> sp|Q96GJ1-2|TRM2_HUMAN Isoform 2 of tRNA (uracil(54)-C(5))-methyltransferase homolog OS=Homo sapiens GN=TRMT2B # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 16.1 0.0 0.00013 0.069 1 59 [. 349 405 .. 349 443 .. 0.88 Alignments for each domain: == domain 1 score: 16.1 bits; conditional E-value: 0.00013 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdll 59 L+i cGtG + l+++ +++++g+++ ++a+eda+ a+++ n ++ + +a+++l sp|Q96GJ1-2|TRM2_HUMAN 349 LDICCGTGVIGLSLAQH--TSRVLGIELLEQAVEDARWTAAFNGITNSEFHTGQAEKIL 405 89***************..************************9999888888877664 PP >> sp|Q96GJ1|TRM2_HUMAN tRNA (uracil(54)-C(5))-methyltransferase homolog OS=Homo sapiens GN=TRMT2B PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 16.1 0.0 0.00013 0.071 1 59 [. 349 405 .. 349 443 .. 0.88 Alignments for each domain: == domain 1 score: 16.1 bits; conditional E-value: 0.00013 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdll 59 L+i cGtG + l+++ +++++g+++ ++a+eda+ a+++ n ++ + +a+++l sp|Q96GJ1|TRM2_HUMAN 349 LDICCGTGVIGLSLAQH--TSRVLGIELLEQAVEDARWTAAFNGITNSEFHTGQAEKIL 405 89***************..************************9999888888877664 PP >> sp|Q9Y5N5-2|HEMK2_HUMAN Isoform 2 of HemK methyltransferase family member 2 OS=Homo sapiens GN=N6AMT1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 16.0 0.0 0.00014 0.076 1 41 [. 50 90 .. 50 104 .. 0.82 Alignments for each domain: == domain 1 score: 16.0 bits; conditional E-value: 0.00014 Methyltransf_12 1 LeiGcGtGsllrallekl.pdieytgvDispsaiedakekla 41 Le+G+G+G +++ l+ + p++ y ++Di+p+a + +++a sp|Q9Y5N5-2|HEMK2_HUMAN 50 LEVGSGSGVVSAFLASMIgPQALYMCTDINPEAA-ACTLETA 90 8*****************9999999*******99.4444444 PP >> sp|O95671-3|ASML_HUMAN Isoform 3 of N-acetylserotonin O-methyltransferase-like protein OS=Homo sapiens GN=ASMTL # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.2 0.0 0.00026 0.14 2 98 .. 399 493 .. 398 494 .. 0.88 Alignments for each domain: == domain 1 score: 15.2 bits; conditional E-value: 0.00026 Methyltransf_12 2 eiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhl..kdireal 86 ++G+ tG+l+r+l+++ p+ ++t+ D+ p+ i +++++ ++ ++ ++++ a d + ++ + s + v++ lh + ++++++l sp|O95671-3|ASML_HUMAN 399 DVGGCTGALARELAREYPRMQVTVFDL-PDII-ELAAHFQPPGP-QAVQIHFAAGDFFRDPLP-SAELYVLCRILHDWpdDKVHKLL 481 89************************9.6777.57777777665.789********8777666.**************988888*** PP Methyltransf_12 87 dniyklLkpgGr 98 +++++ +kpg+ sp|O95671-3|ASML_HUMAN 482 SRVAESCKPGAG 493 *********985 PP >> tr|E7ER97|E7ER97_HUMAN N-acetylserotonin O-methyltransferase-like protein OS=Homo sapiens GN=ASMTL PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.2 0.0 0.00025 0.13 2 98 .. 381 475 .. 380 476 .. 0.88 Alignments for each domain: == domain 1 score: 15.2 bits; conditional E-value: 0.00025 Methyltransf_12 2 eiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhl..kdireal 86 ++G+ tG+l+r+l+++ p+ ++t+ D+ p+ i +++++ ++ ++ ++++ a d + ++ + s + v++ lh + ++++++l tr|E7ER97|E7ER97_HUMAN 381 DVGGCTGALARELAREYPRMQVTVFDL-PDII-ELAAHFQPPGP-QAVQIHFAAGDFFRDPLP-SAELYVLCRILHDWpdDKVHKLL 463 89************************9.6777.57777777665.789********8777666.**************988888*** PP Methyltransf_12 87 dniyklLkpgGr 98 +++++ +kpg+ tr|E7ER97|E7ER97_HUMAN 464 SRVAESCKPGAG 475 *********985 PP >> tr|E9PPP6|E9PPP6_HUMAN Ribosomal RNA-processing protein 8 OS=Homo sapiens GN=RRP8 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.3 0.0 0.00024 0.13 62 99 .] 38 72 .. 19 72 .. 0.76 Alignments for each domain: == domain 1 score: 15.3 bits; conditional E-value: 0.00024 Methyltransf_12 62 dggssfDvvvasnvlhhlkdirealdniyklLkpgGrl 99 d +s+Dv+v + l +ir++l+++ ++LkpgG l tr|E9PPP6|E9PPP6_HUMAN 38 D--ESVDVAVFCLSLMG-TNIRDFLEEANRVLKPGGLL 72 2..59999887777766.5*****************86 PP >> tr|E9PNR9|E9PNR9_HUMAN Protein arginine N-methyltransferase 1 (Fragment) OS=Homo sapiens GN=PRMT1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 16.0 0.0 0.00014 0.074 1 98 [. 47 144 .. 47 145 .. 0.70 Alignments for each domain: == domain 1 score: 16.0 bits; conditional E-value: 0.00014 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.ssfDvvv...asnvlhhlkdir 83 L++G+GtG l + +++ +++g++ s+ + a + ++++ +++ + + ++++ + + +++D+++ + +l + ++ tr|E9PNR9|E9PNR9_HUMAN 47 LDVGSGTGILCMFAAKA-GARKVIGIECSSISD-YAVKIVKANKLDHVVTI--IKGKVEEVELPvEKVDIIIsewMGYCLFYESMLN 129 8***********99999.666777999988888.55566666665553333..3333333333347****99666666666668888 PP Methyltransf_12 84 ealdniyklLkpgGr 98 +l k+L+p+G tr|E9PNR9|E9PNR9_HUMAN 130 TVLYARDKWLAPDGL 144 999999999999997 PP >> sp|O95671|ASML_HUMAN N-acetylserotonin O-methyltransferase-like protein OS=Homo sapiens GN=ASMTL PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.9 0.0 0.0003 0.16 2 98 .. 457 551 .. 456 552 .. 0.88 Alignments for each domain: == domain 1 score: 14.9 bits; conditional E-value: 0.0003 Methyltransf_12 2 eiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhl..kdirealdn 88 ++G+ tG+l+r+l+++ p+ ++t+ D+ p+ i +++++ ++ ++ ++++ a d + ++ + s + v++ lh + ++++++l++ sp|O95671|ASML_HUMAN 457 DVGGCTGALARELAREYPRMQVTVFDL-PDII-ELAAHFQPPGP-QAVQIHFAAGDFFRDPLP-SAELYVLCRILHDWpdDKVHKLLSR 541 89************************9.6777.57777777665.789********8777666.**************988888***** PP Methyltransf_12 89 iyklLkpgGr 98 +++ +kpg+ sp|O95671|ASML_HUMAN 542 VAESCKPGAG 551 *******985 PP >> sp|Q9NR22-2|ANM8_HUMAN Isoform 2 of Protein arginine N-methyltransferase 8 OS=Homo sapiens GN=PRMT8 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.6 0.0 0.00019 0.1 1 98 [. 107 204 .. 107 205 .. 0.69 Alignments for each domain: == domain 1 score: 15.6 bits; conditional E-value: 0.00019 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.ssfDvvv...asnvlhhlkdir 83 L++G+GtG l++ +++ ++ g++ s+ + +ek+ k ++ + n +++++ ++++ + + +++D+++ + +l + ++ sp|Q9NR22-2|ANM8_HUMAN 107 LDVGSGTGILSMFAAKA-GAKKVFGIECSSISD--YSEKIIKANHLD-NIITIFKGKVEEVELPvEKVDIIIsewMGYCLFYESMLN 189 8***********99999.666677877776666..555555544333.455555555555544458***999665556666657777 PP Methyltransf_12 84 ealdniyklLkpgGr 98 ++ k+LkpgG sp|Q9NR22-2|ANM8_HUMAN 190 TVIFARDKWLKPGGL 204 888888899999996 PP >> sp|O95671-2|ASML_HUMAN Isoform 2 of N-acetylserotonin O-methyltransferase-like protein OS=Homo sapiens GN=ASMTL # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.0 0.0 0.00029 0.15 2 98 .. 441 535 .. 440 536 .. 0.88 Alignments for each domain: == domain 1 score: 15.0 bits; conditional E-value: 0.00029 Methyltransf_12 2 eiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhl..kdireal 86 ++G+ tG+l+r+l+++ p+ ++t+ D+ p+ i +++++ ++ ++ ++++ a d + ++ + s + v++ lh + ++++++l sp|O95671-2|ASML_HUMAN 441 DVGGCTGALARELAREYPRMQVTVFDL-PDII-ELAAHFQPPGP-QAVQIHFAAGDFFRDPLP-SAELYVLCRILHDWpdDKVHKLL 523 89************************9.6777.57777777665.789********8777666.**************988888*** PP Methyltransf_12 87 dniyklLkpgGr 98 +++++ +kpg+ sp|O95671-2|ASML_HUMAN 524 SRVAESCKPGAG 535 *********985 PP >> sp|Q9NR22|ANM8_HUMAN Protein arginine N-methyltransferase 8 OS=Homo sapiens GN=PRMT8 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.5 0.0 0.0002 0.1 1 98 [. 116 213 .. 116 214 .. 0.68 Alignments for each domain: == domain 1 score: 15.5 bits; conditional E-value: 0.0002 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.ssfDvvv...asnvlhhlkdirea 85 L++G+GtG l++ +++ ++ g++ s+ + +ek+ k ++ + n +++++ ++++ + + +++D+++ + +l + ++ + sp|Q9NR22|ANM8_HUMAN 116 LDVGSGTGILSMFAAKA-GAKKVFGIECSSISD--YSEKIIKANHLD-NIITIFKGKVEEVELPvEKVDIIIsewMGYCLFYESMLNTV 200 8***********99999.666677877776666..555555544333.455555555555544458***99966555666665777788 PP Methyltransf_12 86 ldniyklLkpgGr 98 + k+LkpgG sp|Q9NR22|ANM8_HUMAN 201 IFARDKWLKPGGL 213 8888899999996 PP >> tr|H3BNT3|H3BNT3_HUMAN UPF0585 protein C16orf13 (Fragment) OS=Homo sapiens GN=C16orf13 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.7 0.0 0.00017 0.091 1 98 [. 14 117 .. 14 118 .. 0.83 Alignments for each domain: == domain 1 score: 15.7 bits; conditional E-value: 0.00017 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsai.edakeklakrennnnnnvnlealdlldldgg...ssfDvvvasnvlhhl..kd 81 Le+ +G+G+ ++++++++p +e +D++++ + a++ a+ n + ++l+++ ++ gg +s D+ +++n h+ + tr|H3BNT3|H3BNT3_HUMAN 14 LEVASGSGQHAAHFARAFPLAEWQPSDVDQRCLdSIAATTQAQGLTNVKAPLHLDVTWGWEHWGGilpQSLDLLLCINMAHVSplRC 100 89*******************************44444444555555555666666666666666*****************999** PP Methyltransf_12 82 irealdniyklLkpgGr 98 ++ +++ + +lLkp + tr|H3BNT3|H3BNT3_HUMAN 101 TEGLFRAAGHLLKPRAL 117 **************976 PP >> tr|H0Y2Q1|H0Y2Q1_HUMAN tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A (Fragment) OS=Homo sapien # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.3 0.0 0.00023 0.12 4 54 .. 13 64 .. 11 104 .. 0.82 Alignments for each domain: == domain 1 score: 15.3 bits; conditional E-value: 0.00023 Methyltransf_12 4 GcGtGsllrallekl.pdieytgvDispsaiedakeklakrennnnnnvnle 54 G+G+Gs+++a+ + + p+ +++ v+++++ e+a+e++++++ ++ v+ + tr|H0Y2Q1|H0Y2Q1_HUMAN 13 GTGSGSVSHAIIRTIaPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQ 64 9**************99*********************99998776666554 PP >> tr|F8VP53|F8VP53_HUMAN 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial (Fragment) OS=Homo sapiens GN # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.0 0.1 0.0012 0.65 1 52 [. 30 115 .. 30 130 .] 0.82 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 0.0012 Methyltransf_12 1 LeiGcGtGsllrallekl..................................pdieytgvDispsaiedakeklakrennnnnnvn 52 L++ +GtG++++++l++ +++++++Di++++++ k+k +++ + + tr|F8VP53|F8VP53_HUMAN 30 LDVAGGTGDIAFRFLNYVqsqhqrkqkrqlraqqnlsweeiakeyqneedslGGSRVVVCDINKEMLKVGKQKALAQGYRAGLAWV 115 89999999999999999999999999999999999999999999999999999**************9999998888776644444 PP >> tr|H3BPE9|H3BPE9_HUMAN Methyltransferase-like protein 9 (Fragment) OS=Homo sapiens GN=METTL9 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.5 0.0 0.00019 0.1 66 95 .. 59 88 .. 38 93 .. 0.85 Alignments for each domain: == domain 1 score: 15.5 bits; conditional E-value: 0.00019 Methyltransf_12 66 sfDvvvasnvlhhlkdirealdniyklLkp 95 ++Dv+ ++n+l ++++ +l+ i+++L p tr|H3BPE9|H3BPE9_HUMAN 59 QYDVISCLNLLDRCDQPLTLLKDIRSVLEP 88 9***************************99 PP >> sp|Q7Z624|CMKMT_HUMAN Calmodulin-lysine N-methyltransferase OS=Homo sapiens GN=CAMKMT PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.2 0.1 0.0005 0.26 50 98 .. 209 256 .. 152 257 .. 0.61 Alignments for each domain: == domain 1 score: 14.2 bits; conditional E-value: 0.0005 Methyltransf_12 50 nvnlealdlldldggssfDvvvasnvlhhlkdirealdniyklLkpgGr 98 ++++++ + ++ + ++fD+v ++++l + +++++d i++lL p G+ sp|Q7Z624|CMKMT_HUMAN 209 VLRWDNETDVSQLE-GHFDIVMCADCLFLDQYRASLVDAIKRLLQPRGK 256 34455555555555.5**********98878888*************97 PP >> tr|H3BMF3|H3BMF3_HUMAN UPF0585 protein C16orf13 (Fragment) OS=Homo sapiens GN=C16orf13 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.4 0.0 0.00022 0.12 1 98 [. 15 118 .. 15 119 .. 0.83 Alignments for each domain: == domain 1 score: 15.4 bits; conditional E-value: 0.00022 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsai.edakeklakrennnnnnvnlealdlldldgg...ssfDvvvasnvlhhl..kd 81 Le+ +G+G+ ++++++++p +e +D++++ + a++ a+ n + ++l+++ ++ gg +s D+ +++n h+ + tr|H3BMF3|H3BMF3_HUMAN 15 LEVASGSGQHAAHFARAFPLAEWQPSDVDQRCLdSIAATTQAQGLTNVKAPLHLDVTWGWEHWGGilpQSLDLLLCINMAHVSplRC 101 89*******************************44444444555555555666666666666666*****************999** PP Methyltransf_12 82 irealdniyklLkpgGr 98 ++ +++ + +lLkp + tr|H3BMF3|H3BMF3_HUMAN 102 TEGLFRAAGHLLKPRAL 118 **************976 PP >> sp|Q96LA8|ANM6_HUMAN Protein arginine N-methyltransferase 6 OS=Homo sapiens GN=PRMT6 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.0 0.0 0.00028 0.15 1 99 [] 87 184 .. 87 184 .. 0.81 Alignments for each domain: == domain 1 score: 15.0 bits; conditional E-value: 0.00028 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvv...as.nvlhhlkdirea 85 L++G+GtG l+ ++++ ++++v+ s+ +a+e ++++ ++ +v++ ++ + ++++D++v + ++lh + ++ sp|Q96LA8|ANM6_HUMAN 87 LDVGAGTGILSIFCAQA-GARRVYAVEASAIWQ-QAREVVRFNGLED--RVHVLPGPVETVELPEQVDAIVsewMGyGLLHE-SMLSSV 170 8*************999.777888999998888.9999999999876..6666666666666667******88866355555.799999 PP Methyltransf_12 86 ldniyklLkpgGrl 99 l+ k+Lk gG l sp|Q96LA8|ANM6_HUMAN 171 LHARTKWLKEGGLL 184 99999*******86 PP >> tr|E9PQ98|E9PQ98_HUMAN Protein arginine N-methyltransferase 1 (Fragment) OS=Homo sapiens GN=PRMT1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.1 0.0 0.00027 0.14 1 98 [. 47 144 .. 47 145 .. 0.70 Alignments for each domain: == domain 1 score: 15.1 bits; conditional E-value: 0.00027 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.ssfDvvv...asnvlhhlkdir 83 L++G+GtG l + +++ +++g++ s+ + a + ++++ +++ + + ++++ + + +++D+++ + +l + ++ tr|E9PQ98|E9PQ98_HUMAN 47 LDVGSGTGILCMFAAKA-GARKVIGIECSSISD-YAVKIVKANKLDHVVTI--IKGKVEEVELPvEKVDIIIsewMGYCLFYESMLN 129 8***********99999.666777999988888.55566666665553333..3333333333347***999666666666668888 PP Methyltransf_12 84 ealdniyklLkpgGr 98 +l k+L+p+G tr|E9PQ98|E9PQ98_HUMAN 130 TVLYARDKWLAPDGL 144 999999999999997 PP >> tr|E9PIX6|E9PIX6_HUMAN Protein arginine N-methyltransferase 1 (Fragment) OS=Homo sapiens GN=PRMT1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.0 0.0 0.00029 0.15 1 98 [. 47 144 .. 47 145 .. 0.70 Alignments for each domain: == domain 1 score: 15.0 bits; conditional E-value: 0.00029 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.ssfDvvv...asnvlhhlkdir 83 L++G+GtG l + +++ +++g++ s+ + a + ++++ +++ + + ++++ + + +++D+++ + +l + ++ tr|E9PIX6|E9PIX6_HUMAN 47 LDVGSGTGILCMFAAKA-GARKVIGIECSSISD-YAVKIVKANKLDHVVTI--IKGKVEEVELPvEKVDIIIsewMGYCLFYESMLN 129 8***********99999.666777999988888.55566666665553333..3333333333347***999666666666668888 PP Methyltransf_12 84 ealdniyklLkpgGr 98 +l k+L+p+G tr|E9PIX6|E9PIX6_HUMAN 130 TVLYARDKWLAPDGL 144 999999999999997 PP >> sp|Q9BV86-2|NTM1A_HUMAN Isoform 2 of N-terminal Xaa-Pro-Lys N-methyltransferase 1 OS=Homo sapiens GN=NTMT1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.8 0.0 0.00032 0.17 1 47 [. 66 111 .. 66 117 .. 0.89 Alignments for each domain: == domain 1 score: 14.8 bits; conditional E-value: 0.00032 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennn 47 L+ G+G G+++++ll e+ vDi ++++ +ak+ l +++++ sp|Q9BV86-2|NTM1A_HUMAN 66 LDCGAGIGRITKRLLLP-LFREVDMVDITEDFLVQAKTYLGEEGKRA 111 899**********9988.899****************9999887765 PP >> sp|Q8IZ69-2|TRM2A_HUMAN Isoform 2 of tRNA (uracil-5-)-methyltransferase homolog A OS=Homo sapiens GN=TRMT2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.2 0.0 0.00052 0.27 1 56 [. 437 490 .. 437 517 .. 0.84 Alignments for each domain: == domain 1 score: 14.2 bits; conditional E-value: 0.00052 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnleal 56 L++ cGtG++ al++k +++gv++ p+a+eda+ +++e n+++ +a+ sp|Q8IZ69-2|TRM2A_HUMAN 437 LDVCCGTGTIGLALARK--VKRVIGVELCPEAVEDARVNAQDNELSNVEFHCGRAE 490 89***************..**************99999999988766555444444 PP >> sp|Q96S19|CP013_HUMAN UPF0585 protein C16orf13 OS=Homo sapiens GN=C16orf13 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.8 0.0 0.00033 0.17 1 98 [. 32 135 .. 32 136 .. 0.83 Alignments for each domain: == domain 1 score: 14.8 bits; conditional E-value: 0.00033 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsai.edakeklakrennnnnnvnlealdlldldgg...ssfDvvvasnvlhhl..kdi 82 Le+ +G+G+ ++++++++p +e +D++++ + a++ a+ n + ++l+++ ++ gg +s D+ +++n h+ + + sp|Q96S19|CP013_HUMAN 32 LEVASGSGQHAAHFARAFPLAEWQPSDVDQRCLdSIAATTQAQGLTNVKAPLHLDVTWGWEHWGGilpQSLDLLLCINMAHVSplRCT 119 89*******************************44444444554555555666666666666666*****************999*** PP Methyltransf_12 83 realdniyklLkpgGr 98 + +++ + +lLkp + sp|Q96S19|CP013_HUMAN 120 EGLFRAAGHLLKPRAL 135 *************976 PP >> sp|Q96S19-4|CP013_HUMAN Isoform 4 of UPF0585 protein C16orf13 OS=Homo sapiens GN=C16orf13 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.8 0.0 0.00033 0.17 1 98 [. 32 135 .. 32 136 .. 0.83 Alignments for each domain: == domain 1 score: 14.8 bits; conditional E-value: 0.00033 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsai.edakeklakrennnnnnvnlealdlldldgg...ssfDvvvasnvlhhl..k 80 Le+ +G+G+ ++++++++p +e +D++++ + a++ a+ n + ++l+++ ++ gg +s D+ +++n h+ + sp|Q96S19-4|CP013_HUMAN 32 LEVASGSGQHAAHFARAFPLAEWQPSDVDQRCLdSIAATTQAQGLTNVKAPLHLDVTWGWEHWGGilpQSLDLLLCINMAHVSplR 117 89*******************************44444444554555555666666666666666*****************999* PP Methyltransf_12 81 direaldniyklLkpgGr 98 ++ +++ + +lLkp + sp|Q96S19-4|CP013_HUMAN 118 CTEGLFRAAGHLLKPRAL 135 ***************976 PP >> sp|Q96FX7|TRM61_HUMAN tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A OS=Homo sapiens GN=TRMT61A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.6 0.0 0.00039 0.2 2 54 .. 109 162 .. 108 202 .. 0.83 Alignments for each domain: == domain 1 score: 14.6 bits; conditional E-value: 0.00039 Methyltransf_12 2 eiGcGtGsllrallekl.pdieytgvDispsaiedakeklakrennnnnnvnle 54 e G+G+Gs+++a+ + + p+ +++ v+++++ e+a+e++++++ ++ v+ + sp|Q96FX7|TRM61_HUMAN 109 ESGTGSGSVSHAIIRTIaPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQ 162 569**************99*********************99998776666554 PP >> tr|E9PHY1|E9PHY1_HUMAN Low-density lipoprotein receptor-related protein 5 OS=Homo sapiens GN=LRP5 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.3 0.0 0.31 1.7e+02 17 41 .. 71 93 .. 61 112 .. 0.70 2 ? 4.0 0.0 0.77 4.1e+02 8 43 .. 235 270 .. 233 279 .. 0.85 Alignments for each domain: == domain 1 score: 5.3 bits; conditional E-value: 0.31 Methyltransf_12 17 klpdieytgvDispsaiedakekla 41 +++ ++++D+s++ai +++ l+ tr|E9PHY1|E9PHY1_HUMAN 71 QFSKGAVYWTDVSEEAI--KQTYLN 93 4567899**********..333333 PP == domain 2 score: 4.0 bits; conditional E-value: 0.77 Methyltransf_12 8 GsllralleklpdieytgvDispsaiedakeklakr 43 Gsl+++++ l++ +++++D ++++i++ +++ + tr|E9PHY1|E9PHY1_HUMAN 235 GSLTHPFALTLSGDTLYWTDWQTRSIHACNKRTGGK 270 999***********************7777766554 PP >> tr|H0YDE4|H0YDE4_HUMAN Protein arginine N-methyltransferase 1 (Fragment) OS=Homo sapiens GN=PRMT1 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.6 0.0 0.00039 0.21 1 98 [. 103 200 .. 103 201 .. 0.70 Alignments for each domain: == domain 1 score: 14.6 bits; conditional E-value: 0.00039 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.ssfDvvv...asnvlhhlkdir 83 L++G+GtG l + +++ +++g++ s+ + a + ++++ +++ + + ++++ + + +++D+++ + +l + ++ tr|H0YDE4|H0YDE4_HUMAN 103 LDVGSGTGILCMFAAKA-GARKVIGIECSSISD-YAVKIVKANKLDHVVTI--IKGKVEEVELPvEKVDIIIsewMGYCLFYESMLN 185 8***********99999.666777999988888.55566666665553333..3333333333347***999666666666668888 PP Methyltransf_12 84 ealdniyklLkpgGr 98 +l k+L+p+G tr|H0YDE4|H0YDE4_HUMAN 186 TVLYARDKWLAPDGL 200 999999999999997 PP >> tr|A8MT87|A8MT87_HUMAN Phenylethanolamine N-methyltransferase OS=Homo sapiens GN=PNMT PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.7 0.0 0.00036 0.19 64 99 .] 72 113 .. 38 113 .. 0.75 Alignments for each domain: == domain 1 score: 14.7 bits; conditional E-value: 0.00036 Methyltransf_12 64 g..ssfDvvvasnvlhhl....kdirealdniyklLkpgGrl 99 + D+ v++++l+++ + ++ald+i lL+pgG+l tr|A8MT87|A8MT87_HUMAN 72 PapLPADALVSAFCLEAVspdlASFQRALDHITTLLRPGGHL 113 255689*************9999999**************97 PP >> sp|Q8IZ69|TRM2A_HUMAN tRNA (uracil-5-)-methyltransferase homolog A OS=Homo sapiens GN=TRMT2A PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.0 0.0 0.0006 0.32 1 56 [. 437 490 .. 437 517 .. 0.84 Alignments for each domain: == domain 1 score: 14.0 bits; conditional E-value: 0.0006 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnleal 56 L++ cGtG++ al++k +++gv++ p+a+eda+ +++e n+++ +a+ sp|Q8IZ69|TRM2A_HUMAN 437 LDVCCGTGTIGLALARK--VKRVIGVELCPEAVEDARVNAQDNELSNVEFHCGRAE 490 89***************..**************99999999988766555444444 PP >> sp|Q8N4J0|CI041_HUMAN UPF0586 protein C9orf41 OS=Homo sapiens GN=C9orf41 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 0.0 0.001 0.52 56 98 .. 278 337 .. 207 338 .. 0.71 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 0.001 Methyltransf_12 56 ldlldldgg.................ssfDvvvasnvlhhlkdirealdniyklLkpgGr 98 d ++l++g +++D + ++++ ++ +++d i k LkpgG+ sp|Q8N4J0|CI041_HUMAN 278 VDPHSLPPGsnfsmtagdfqeiysecNTWDCIATCFFIDTAHNVIDYIDTIWKILKPGGI 337 333333333777777777888888899********************************6 PP >> tr|K7ES84|K7ES84_HUMAN Protein FAM86A OS=Homo sapiens GN=FAM86A PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.0 0.0 0.0012 0.64 1 92 [. 101 205 .. 101 209 .. 0.81 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 0.0012 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.................ssfDvv 70 Le+G+G G + a+++ ++ y+++D +++++ e+l+ + n ++ + + ld++ + Dvv tr|K7ES84|K7ES84_HUMAN 101 LELGSGAGLTGLAICKMCRPRAYIFSDCHSRVL----EQLRGNVLLNGLSLEADITAKLDSPRVtvaqldwdvatvhqlsaFQPDVV 183 8********************************....88888888777777777776555544499998888999988877788999 PP Methyltransf_12 71 vasnvlhhlkdirealdniykl 92 +a++vl + + i +++ +++l tr|K7ES84|K7ES84_HUMAN 184 IAADVLYCPEAIMSLVGVLRRL 205 9999998877766666666555 PP >> sp|Q8N7N1|F86B1_HUMAN Protein FAM86B1 OS=Homo sapiens GN=FAM86B1 PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 0.0 0.00096 0.51 1 88 [. 128 228 .. 128 236 .. 0.78 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 0.00096 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg...................ssfDv 69 Le+G+G G + a+++ ++ y+++D++++++ e+l+ + n ++ + + +ld++ + Dv sp|Q8N7N1|F86B1_HUMAN 128 LELGSGAGLTGLAICKMCRPRAYIFSDPHSRVL----EQLRGNVLLNGLSLEADITG--NLDSPrvtvaqldwdvamvhqlsaFQPDV 209 8********************************....88888887766565555554..44444568989888899999997778899 PP Methyltransf_12 70 vvasnvlhhlkdirealdn 88 v+a++vl + + i +++ sp|Q8N7N1|F86B1_HUMAN 210 VIAADVLYCPEAIVSLVGV 228 9999999887766666555 PP >> tr|F8VZA8|F8VZA8_HUMAN Methyltransferase-like protein 25 (Fragment) OS=Homo sapiens GN=METTL25 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.1 0.0 0.0011 0.58 2 49 .. 180 225 .. 179 237 .. 0.81 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 0.0011 Methyltransf_12 2 eiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnn 49 ++G+G G l++ l k +++++g+D s + a+e+ +k ++ +++ tr|F8VZA8|F8VZA8_HUMAN 180 DLGSGKGYLSSFLSLK-YGLKVYGIDSSNTNTHGAEERNRKLKK-HWK 225 9************999.9**************777777777764.444 PP >> sp|P11086|PNMT_HUMAN Phenylethanolamine N-methyltransferase OS=Homo sapiens GN=PNMT PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.6 0.0 0.0008 0.42 64 99 .] 170 211 .. 136 211 .. 0.75 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 0.0008 Methyltransf_12 64 g..ssfDvvvasnvlhhl....kdirealdniyklLkpgGrl 99 + D+ v++++l+++ + ++ald+i lL+pgG+l sp|P11086|PNMT_HUMAN 170 PapLPADALVSAFCLEAVspdlASFQRALDHITTLLRPGGHL 211 255689*************9999999**************97 PP >> tr|E9PN63|E9PN63_HUMAN Protein FAM86B1 OS=Homo sapiens GN=FAM86B1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.0 0.0 0.0012 0.63 1 88 [. 162 262 .. 162 270 .. 0.78 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 0.0012 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg...................ssfD 68 Le+G+G G + a+++ ++ y+++D++++++ e+l+ + n ++ + + +ld++ + D tr|E9PN63|E9PN63_HUMAN 162 LELGSGAGLTGLAICKMCRPRAYIFSDPHSRVL----EQLRGNVLLNGLSLEADITG--NLDSPrvtvaqldwdvamvhqlsaFQPD 242 8********************************....88888887665555555554..4444456888888889999999777889 PP Methyltransf_12 69 vvvasnvlhhlkdirealdn 88 vv+a++vl + + i +++ tr|E9PN63|E9PN63_HUMAN 243 VVIAADVLYCPEAIVSLVGV 262 99999999887766666555 PP >> sp|Q96G04-2|FA86A_HUMAN Isoform 2 of Protein FAM86A OS=Homo sapiens GN=FAM86A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.7 0.0 0.0015 0.78 1 92 [. 128 232 .. 128 236 .. 0.81 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 0.0015 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.................ssfDv 69 Le+G+G G + a+++ ++ y+++D +++++ e+l+ + n ++ + + ld++ + Dv sp|Q96G04-2|FA86A_HUMAN 128 LELGSGAGLTGLAICKMCRPRAYIFSDCHSRVL----EQLRGNVLLNGLSLEADITAKLDSPRVtvaqldwdvatvhqlsaFQPDV 209 8********************************....8888888877777777777655554449999888888888887778899 PP Methyltransf_12 70 vvasnvlhhlkdirealdniykl 92 v+a++vl + + i +++ +++l sp|Q96G04-2|FA86A_HUMAN 210 VIAADVLYCPEAIMSLVGVLRRL 232 99999998877766666666555 PP >> tr|H0YIW7|H0YIW7_HUMAN Methyltransferase-like protein 25 (Fragment) OS=Homo sapiens GN=METTL25 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.9 0.0 0.0013 0.67 2 47 .. 139 182 .. 138 189 .. 0.85 Alignments for each domain: == domain 1 score: 12.9 bits; conditional E-value: 0.0013 Methyltransf_12 2 eiGcGtGsllralleklpdieytgvDispsaiedakeklakrennn 47 ++G+G G l++ l k +++++g+D s + a+e+ +k ++ + tr|H0YIW7|H0YIW7_HUMAN 139 DLGSGKGYLSSFLSLK-YGLKVYGIDSSNTNTHGAEERNRKLKK-H 182 9************999.9**************778777777664.4 PP >> sp|Q99873-3|ANM1_HUMAN Isoform 3 of Protein arginine N-methyltransferase 1 OS=Homo sapiens GN=PRMT1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 0.00084 0.44 1 98 [. 65 162 .. 65 163 .. 0.70 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 0.00084 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.ssfDvvv...asnvlhhlkdir 83 L++G+GtG l + +++ +++g++ s+ + a + ++++ +++ + + ++++ + + +++D+++ + +l + ++ sp|Q99873-3|ANM1_HUMAN 65 LDVGSGTGILCMFAAKA-GARKVIGIECSSISD-YAVKIVKANKLDHVVTI--IKGKVEEVELPvEKVDIIIsewMGYCLFYESMLN 147 8***********99999.666777999988888.55566666665553333..3333333333347***999666666666668888 PP Methyltransf_12 84 ealdniyklLkpgGr 98 +l k+L+p+G sp|Q99873-3|ANM1_HUMAN 148 TVLYARDKWLAPDGL 162 999999999999997 PP >> tr|E9PKG1|E9PKG1_HUMAN Protein arginine N-methyltransferase 1 OS=Homo sapiens GN=PRMT1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.7 0.0 0.00076 0.4 1 98 [. 47 144 .. 47 145 .. 0.70 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 0.00076 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.ssfDvvv...asnvlhhlkdir 83 L++G+GtG l + +++ +++g++ s+ + a + ++++ +++ + + ++++ + + +++D+++ + +l + ++ tr|E9PKG1|E9PKG1_HUMAN 47 LDVGSGTGILCMFAAKA-GARKVIGIECSSISD-YAVKIVKANKLDHVVTI--IKGKVEEVELPvEKVDIIIsewMGYCLFYESMLN 129 8***********99999.666777999988888.55566666665553333..3333333333347***999666666666668888 PP Methyltransf_12 84 ealdniyklLkpgGr 98 +l k+L+p+G tr|E9PKG1|E9PKG1_HUMAN 130 TVLYARDKWLAPDGL 144 999999999999997 PP >> sp|Q99873-4|ANM1_HUMAN Isoform 4 of Protein arginine N-methyltransferase 1 OS=Homo sapiens GN=PRMT1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.4 0.0 0.00089 0.47 1 98 [. 75 172 .. 75 173 .. 0.70 Alignments for each domain: == domain 1 score: 13.4 bits; conditional E-value: 0.00089 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.ssfDvvv...asnvlhhlkdir 83 L++G+GtG l + +++ +++g++ s+ + a + ++++ +++ + + ++++ + + +++D+++ + +l + ++ sp|Q99873-4|ANM1_HUMAN 75 LDVGSGTGILCMFAAKA-GARKVIGIECSSISD-YAVKIVKANKLDHVVTI--IKGKVEEVELPvEKVDIIIsewMGYCLFYESMLN 157 8***********99999.666777999988888.55566666665553333..3333333333347***999666666666668888 PP Methyltransf_12 84 ealdniyklLkpgGr 98 +l k+L+p+G sp|Q99873-4|ANM1_HUMAN 158 TVLYARDKWLAPDGL 172 999999999999997 PP >> sp|Q99873-2|ANM1_HUMAN Isoform 2 of Protein arginine N-methyltransferase 1 OS=Homo sapiens GN=PRMT1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 0.00086 0.45 1 98 [. 69 166 .. 69 167 .. 0.70 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 0.00086 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.ssfDvvv...asnvlhhlkdir 83 L++G+GtG l + +++ +++g++ s+ + a + ++++ +++ + + ++++ + + +++D+++ + +l + ++ sp|Q99873-2|ANM1_HUMAN 69 LDVGSGTGILCMFAAKA-GARKVIGIECSSISD-YAVKIVKANKLDHVVTI--IKGKVEEVELPvEKVDIIIsewMGYCLFYESMLN 151 8***********99999.666777999988888.55566666665553333..3333333333347***999666666666668888 PP Methyltransf_12 84 ealdniyklLkpgGr 98 +l k+L+p+G sp|Q99873-2|ANM1_HUMAN 152 TVLYARDKWLAPDGL 166 999999999999997 PP >> tr|B7U631|B7U631_HUMAN PRMT2 beta variant OS=Homo sapiens GN=PRMT2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.6 0.0 0.0008 0.42 1 79 [. 142 221 .. 142 229 .. 0.72 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 0.0008 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvv...as.nvlhhl 79 L++GcGtG ++ ++ + ++ +++v+ s+ a ++ + +++ ++ +++ +++++d ++++Dv v + ++lhh+ tr|B7U631|B7U631_HUMAN 142 LDVGCGTGIISLFCAHYARPRAVYAVEASEMAQ-HTGQLVLQNGF--ADIITVYQQKVEDVVLPEKVDVLVsewMGtCLLHHT 221 8*****************************999.55555555553..445555555555555556999987666333777776 PP >> sp|Q99873|ANM1_HUMAN Protein arginine N-methyltransferase 1 OS=Homo sapiens GN=PRMT1 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.4 0.0 0.00093 0.49 1 98 [. 83 180 .. 83 181 .. 0.70 Alignments for each domain: == domain 1 score: 13.4 bits; conditional E-value: 0.00093 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.ssfDvvv...asnvlhhlkdirea 85 L++G+GtG l + +++ +++g++ s+ + a + ++++ +++ + + ++++ + + +++D+++ + +l + ++ + sp|Q99873|ANM1_HUMAN 83 LDVGSGTGILCMFAAKA-GARKVIGIECSSISD-YAVKIVKANKLDHVVTI--IKGKVEEVELPvEKVDIIIsewMGYCLFYESMLNTV 167 8***********99999.666777999988888.55566666665553333..3333333333347***99966666666666888899 PP Methyltransf_12 86 ldniyklLkpgGr 98 l k+L+p+G sp|Q99873|ANM1_HUMAN 168 LYARDKWLAPDGL 180 9999999999997 PP >> sp|Q96G04|FA86A_HUMAN Protein FAM86A OS=Homo sapiens GN=FAM86A PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.0 0.0019 0.98 1 92 [. 162 266 .. 162 270 .. 0.81 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 0.0019 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.................ssfDvvv 71 Le+G+G G + a+++ ++ y+++D +++++ e+l+ + n ++ + + ld++ + Dvv+ sp|Q96G04|FA86A_HUMAN 162 LELGSGAGLTGLAICKMCRPRAYIFSDCHSRVL----EQLRGNVLLNGLSLEADITAKLDSPRVtvaqldwdvatvhqlsaFQPDVVI 245 8********************************....888888887777777777765555444999988888888888777889999 PP Methyltransf_12 72 asnvlhhlkdirealdniykl 92 a++vl + + i +++ +++l sp|Q96G04|FA86A_HUMAN 246 AADVLYCPEAIMSLVGVLRRL 266 999998877766666666555 PP >> sp|Q8N6R0-3|MET13_HUMAN Isoform 3 of Methyltransferase-like protein 13 OS=Homo sapiens GN=METTL13 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.7 0.0 0.48 2.5e+02 62 98 .. 23 62 .. 2 69 .. 0.72 2 ? 5.0 0.0 0.37 2e+02 2 44 .. 413 455 .. 412 490 .. 0.82 Alignments for each domain: == domain 1 score: 4.7 bits; conditional E-value: 0.48 Methyltransf_12 62 dgg.ssfDvvvasnvlhhl..kdirealdniyklLkpgGr 98 + + +sf vv+ ++l ++ ++ +++l+++ ++L+ Gr sp|Q8N6R0-3|MET13_HUMAN 23 EFPdASFQVVLDKGTLDAVltDEEEKTLQQVDRMLAEVGR 62 222579*************987777888888888887665 PP == domain 2 score: 5.0 bits; conditional E-value: 0.37 Methyltransf_12 2 eiGcGtGsllralleklpdieytgvDispsaiedakeklakre 44 +G G Gsl + +++p + + +v+i+ps++e a + + + + sp|Q8N6R0-3|MET13_HUMAN 413 VVGLGGGSLPLFVHDHFPKSCIDAVEIDPSMLEVATQWFGFSQ 455 6899****************************88887666555 PP >> tr|H7C2I1|H7C2I1_HUMAN Protein arginine N-methyltransferase 1 OS=Homo sapiens GN=PRMT1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 0.0 0.00097 0.51 1 98 [. 93 190 .. 93 191 .. 0.70 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 0.00097 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.ssfDvvv...asnvlhhlkdir 83 L++G+GtG l + +++ +++g++ s+ + a + ++++ +++ + + ++++ + + +++D+++ + +l + ++ tr|H7C2I1|H7C2I1_HUMAN 93 LDVGSGTGILCMFAAKA-GARKVIGIECSSISD-YAVKIVKANKLDHVVTI--IKGKVEEVELPvEKVDIIIsewMGYCLFYESMLN 175 8***********99999.666777999988888.55566666665553333..3333333333347***999666666666668888 PP Methyltransf_12 84 ealdniyklLkpgGr 98 +l k+L+p+G tr|H7C2I1|H7C2I1_HUMAN 176 TVLYARDKWLAPDGL 190 999999999999997 PP >> tr|H3BQ23|H3BQ23_HUMAN Anamorsin (Fragment) OS=Homo sapiens GN=CIAPIN1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.8 0.0 0.00067 0.35 49 99 .] 38 93 .. 10 93 .. 0.72 Alignments for each domain: == domain 1 score: 13.8 bits; conditional E-value: 0.00067 Methyltransf_12 49 nnvnlealdlldldgg....ssfDvvvasnvlhhl.kdirealdniyklLkpgGrl 99 n+ ++ ++++ +l + ssfD++++ v + + +e+l++i++ L+pgG+l tr|H3BQ23|H3BQ23_HUMAN 38 NEGRVSVENIKQLLQSahkeSSFDIILSGLVPGSTtLHSAEILAEIARILRPGGCL 93 333333334333333344569******9999988878888**************97 PP >> tr|B7U630|B7U630_HUMAN PRMT2 alpha variant OS=Homo sapiens GN=PRMT2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 0.00084 0.44 1 98 [. 142 239 .. 142 240 .. 0.67 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 0.00084 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvv...asnvlhhl...kd 81 L++GcGtG ++ ++ + ++ +++v+ s+ a ++ + +++ ++ +++ +++++d ++++Dv v + + l tr|B7U630|B7U630_HUMAN 142 LDVGCGTGIISLFCAHYARPRAVYAVEASEMAQ-HTGQLVLQNGF--ADIITVYQQKVEDVVLPEKVDVLVsewMGTC---LlfeFM 222 8*****************************999.55555555553..4455555555555555569999883332222...222355 PP Methyltransf_12 82 irealdniyklLkpgGr 98 i+++l ++Lk +G+ tr|B7U630|B7U630_HUMAN 223 IESILYARDAWLKEDGV 239 66666666677777775 PP >> sp|Q96MG8|PCMD1_HUMAN Protein-L-isoaspartate O-methyltransferase domain-containing protein 1 OS=Homo sapiens GN=PCMT # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.9 0.0 0.0013 0.69 1 72 [. 85 165 .. 85 186 .. 0.89 Alignments for each domain: == domain 1 score: 12.9 bits; conditional E-value: 0.0013 Methyltransf_12 1 LeiGcGtGsllrallekl.pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg........ssfDvvva 72 L +G+GtG l+ ++ l p +g++++++++e akekl + ++n+ ++ ++e ++ + g+ +++D +++ sp|Q96MG8|PCMD1_HUMAN 85 LNLGSGTGYLSTMVGLILgPFGINHGIELHSDVVEYAKEKLESFIKNSDSFDKFEFCEPAFVVGNclqiasdsHQYDRIYC 165 679***********99998888889**********************9999999999988777778888888888888877 PP >> tr|E9PQV7|E9PQV7_HUMAN Protein FAM86B2 (Fragment) OS=Homo sapiens GN=FAM86B2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.0 0.0021 1.1 1 88 [. 128 228 .. 128 236 .. 0.78 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 0.0021 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg...................ssfD 68 Le+G+G G + a+++ ++ y+++D++++ + e+l+ + n ++ + + +ld++ + D tr|E9PQV7|E9PQV7_HUMAN 128 LELGSGAGLTGLAICKMCRPRAYIFSDPHSRIL----EQLRGNVLLNGLSLEADITG--NLDSPrvtvaqldwdvamvhqlsaFQPD 208 8********************************....88888887665555555554..4444456888888889999999777889 PP Methyltransf_12 69 vvvasnvlhhlkdirealdn 88 vv+a++vl + + i +++ tr|E9PQV7|E9PQV7_HUMAN 209 VVIAADVLYCPEAIVSLVGV 228 99999999887766666555 PP >> tr|H7BXI9|H7BXI9_HUMAN Protein FAM86B2 OS=Homo sapiens GN=FAM86B2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.0 0.0021 1.1 1 88 [. 128 228 .. 128 236 .. 0.78 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 0.0021 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg...................ssfD 68 Le+G+G G + a+++ ++ y+++D++++ + e+l+ + n ++ + + +ld++ + D tr|H7BXI9|H7BXI9_HUMAN 128 LELGSGAGLTGLAICKMCRPRAYIFSDPHSRIL----EQLRGNVLLNGLSLEADITG--NLDSPrvtvaqldwdvamvhqlsaFQPD 208 8********************************....88888887665555555554..4444456888888889999999777889 PP Methyltransf_12 69 vvvasnvlhhlkdirealdn 88 vv+a++vl + + i +++ tr|H7BXI9|H7BXI9_HUMAN 209 VVIAADVLYCPEAIVSLVGV 228 99999999887766666555 PP >> tr|B1ANH5|B1ANH5_HUMAN Guanylate kinase OS=Homo sapiens GN=GUK1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.4 0.0 2.4 1.2e+03 4 32 .. 14 40 .. 13 114 .. 0.79 2 ? 9.8 0.1 0.012 6.2 34 87 .. 134 188 .. 91 198 .. 0.78 Alignments for each domain: == domain 1 score: 2.4 bits; conditional E-value: 2.4 Methyltransf_12 4 GcGtGsllralleklpdieytgvDispsa 32 G+G ++ll++ll++ ++ + g +s+++ tr|B1ANH5|B1ANH5_HUMAN 14 GAGKSTLLKRLLQE--HSGIFGFSVSRES 40 99**********99..6666666666554 PP == domain 2 score: 9.8 bits; conditional E-value: 0.012 Methyltransf_12 34 edakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhl.kdireald 87 ++ +++ + e+ ++++ + d++++++++ fDvv++++ l ++++eal+ tr|B1ANH5|B1ANH5_HUMAN 134 QRLRQRNTETEESLVKRLAAAQADMESSKEPGLFDVVIINDSLDQAyAELKEALS 188 4456666667777788889999999988888*********999888777777765 PP >> sp|Q8N6Q8|MET25_HUMAN Methyltransferase-like protein 25 OS=Homo sapiens GN=METTL25 PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.8 0.1 0.003 1.6 2 51 .. 180 227 .. 179 298 .. 0.86 Alignments for each domain: == domain 1 score: 11.8 bits; conditional E-value: 0.003 Methyltransf_12 2 eiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnv 51 ++G+G G l++ l k +++++g+D s + a+e+ +k ++ +++ + sp|Q8N6Q8|MET25_HUMAN 180 DLGSGKGYLSSFLSLK-YGLKVYGIDSSNTNTHGAEERNRKLKK-HWKLC 227 9************999.9**************777777777765.44433 PP >> tr|G3V353|G3V353_HUMAN Methyltransferase-like protein 17, mitochondrial (Fragment) OS=Homo sapiens GN=METTL17 PE=2 S # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.0 0.0023 1.2 1 41 [. 108 150 .. 108 157 .. 0.80 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 0.0023 Methyltransf_12 1 LeiGcGtGsllrallekl..pdieytgvDispsaiedakekla 41 +++G+GtGs++ a + ey +vD s++++ a++ l+ tr|G3V353|G3V353_HUMAN 108 MDFGSGTGSVTWAAHSIWgqSLREYMCVDRSAAMLVLAEKLLK 150 69********99985555888999***********55555444 PP >> sp|P0C5J1|F86B2_HUMAN Protein FAM86B2 OS=Homo sapiens GN=FAM86B2 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 0.0 0.0026 1.4 1 88 [. 162 262 .. 162 270 .. 0.78 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 0.0026 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg...................ssfDv 69 Le+G+G G + a+++ ++ y+++D++++ + e+l+ + n ++ + + +ld++ + Dv sp|P0C5J1|F86B2_HUMAN 162 LELGSGAGLTGLAICKMCRPRAYIFSDPHSRIL----EQLRGNVLLNGLSLEADITG--NLDSPrvtvaqldwdvamvhqlsaFQPDV 243 8********************************....88888887665555555554..44444568888888899999997777899 PP Methyltransf_12 70 vvasnvlhhlkdirealdn 88 v+a++vl + + i +++ sp|P0C5J1|F86B2_HUMAN 244 VIAADVLYCPEAIVSLVGV 262 9999999887766666555 PP >> sp|A6NDL7|MT21E_HUMAN Putative methyltransferase-like protein 21E pseudogene OS=Homo sapiens GN=METTL21EP PE=5 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.0 0.0022 1.1 2 92 .. 122 216 .. 121 223 .. 0.66 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 0.0022 Methyltransf_12 2 eiGcGtGsllralleklpdieytgvDispsai.....edakeklakrennnnnnvnlealdlldldgg......ssfDvvvasnvlhh 78 eiG+GtG ++ + ++++t++D+ + + +k+++++ +++++ + + + + fD+++a++v+ + sp|A6NDL7|MT21E_HUMAN 122 EIGAGTGLVSIVASLL--GAHVTATDLPELLGnlqynISRNTKMKSKHLPQVKELSWGVALD-----TnfprssNNFDYILAADVVYA 202 9******999999888..********987655333332444444444444555555554443.....03445799********99877 PP Methyltransf_12 79 lkdirealdniykl 92 + ++e+l + +l sp|A6NDL7|MT21E_HUMAN 203 HPFLEELLITFDHL 216 66666666555555 PP >> sp|Q5VZV1|MT21C_HUMAN Protein-lysine methyltransferase METTL21C OS=Homo sapiens GN=METTL21C PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 0.1 0.0027 1.4 1 90 [. 117 210 .. 117 219 .. 0.64 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 0.0027 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.......ssfDvvvasnvlhhlkd 81 LeiG+G G ++ + ++++t++D+ + + l k+ ++++++ ++ + +d ++D+v+as+v+ h sp|Q5VZV1|MT21C_HUMAN 117 LEIGAGPGLVSIVASIL--GAQVTATDLPDVLG-NLQYNLLKNTLQCTAHLPEVKELVWGEDLDknfpksaFYYDYVLASDVVYHHYF 201 89******888887666..99******955444.55555555555544444333333322222256888999********99887655 PP Methyltransf_12 82 irealdniy 90 ++++l + sp|Q5VZV1|MT21C_HUMAN 202 LDKLLTTMV 210 556665555 PP >> tr|H7C2H9|H7C2H9_HUMAN Protein arginine N-methyltransferase 2 (Fragment) OS=Homo sapiens GN=PRMT2 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.9 0.0 0.0013 0.7 1 71 [. 82 149 .. 82 164 .. 0.72 Alignments for each domain: == domain 1 score: 12.9 bits; conditional E-value: 0.0013 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvv 71 L++GcGtG ++ ++ + ++ +++v+ s+ a ++ + +++ ++ +++ +++++d ++++Dv v tr|H7C2H9|H7C2H9_HUMAN 82 LDVGCGTGIISLFCAHYARPRAVYAVEASEMAQ-HTGQLVLQNGF--ADIITVYQQKVEDVVLPEKVDVLV 149 8****************9***********9998.44444444443..334444444444444445677665 PP >> tr|B1ANH6|B1ANH6_HUMAN Guanylate kinase OS=Homo sapiens GN=GUK1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.5 0.0 9.5 5e+03 4 23 .. 14 31 .. 13 56 .. 0.82 2 ? 10.7 0.0 0.0065 3.4 32 90 .. 129 187 .. 95 195 .. 0.84 Alignments for each domain: == domain 1 score: 0.5 bits; conditional E-value: 9.5 Methyltransf_12 4 GcGtGsllralleklpdiey 23 G+G ++ll++ll+++ + + tr|B1ANH6|B1ANH6_HUMAN 14 GAGKSTLLKRLLQEH--SGI 31 99**********994..433 PP == domain 2 score: 10.7 bits; conditional E-value: 0.0065 Methyltransf_12 32 aiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhl.kdirealdniy 90 ++ + +++ + e+ ++++ + d++++++++ fDvv++++ l ++++eal+++ tr|B1ANH6|B1ANH6_HUMAN 129 VL-RLRQRNTETEESLVKRLAAAQADMESSKEPGLFDVVIINDSLDQAyAELKEALSEVG 187 44.778888888888999999999999999999*********999988899999999886 PP >> sp|P55345|ANM2_HUMAN Protein arginine N-methyltransferase 2 OS=Homo sapiens GN=PRMT2 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 0.0 0.0018 0.93 1 98 [. 142 239 .. 142 240 .. 0.66 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 0.0018 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvv...asnvlhhl...kdir 83 L++GcGtG ++ ++ + ++ +++v+ s+ a ++ + +++ ++ +++ +++++d ++++Dv v + + l i+ sp|P55345|ANM2_HUMAN 142 LDVGCGTGIISLFCAHYARPRAVYAVEASEMAQ-HTGQLVLQNGF--ADIITVYQQKVEDVVLPEKVDVLVsewMGTC---LlfeFMIE 224 8*****************************999.55555555553..4455555555555555568999883332222...22235566 PP Methyltransf_12 84 ealdniyklLkpgGr 98 ++l ++Lk +G+ sp|P55345|ANM2_HUMAN 225 SILYARDAWLKEDGV 239 666666667776665 PP >> tr|H3BUG4|H3BUG4_HUMAN Anamorsin OS=Homo sapiens GN=CIAPIN1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 0.0 0.0017 0.92 51 99 .] 40 93 .. 14 93 .. 0.71 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 0.0017 Methyltransf_12 51 vnlealdlldldgg....ssfDvvvasnvlhhl.kdirealdniyklLkpgGrl 99 ++ ++++ +l + ssfD++++ v + + +e+l++i++ L+pgG+l tr|H3BUG4|H3BUG4_HUMAN 40 GRVSVENIKQLLQSahkeSSFDIILSGLVPGSTtLHSAEILAEIARILRPGGCL 93 3333333333333344559******9999988878888**************97 PP >> sp|Q16774|KGUA_HUMAN Guanylate kinase OS=Homo sapiens GN=GUK1 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.9 0.0 6.9 3.7e+03 4 23 .. 14 31 .. 13 57 .. 0.82 2 ? 9.9 0.0 0.011 5.9 34 87 .. 132 186 .. 87 196 .. 0.79 Alignments for each domain: == domain 1 score: 0.9 bits; conditional E-value: 6.9 Methyltransf_12 4 GcGtGsllralleklpdiey 23 G+G ++ll++ll+++ + + sp|Q16774|KGUA_HUMAN 14 GAGKSTLLKRLLQEH--SGI 31 99**********994..443 PP == domain 2 score: 9.9 bits; conditional E-value: 0.011 Methyltransf_12 34 edakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhl.kdireald 87 ++ +++ + e+ ++++ + d++++++++ fDvv++++ l ++++eal+ sp|Q16774|KGUA_HUMAN 132 QRLRQRNTETEESLVKRLAAAQADMESSKEPGLFDVVIINDSLDQAyAELKEALS 186 4456666667777788889999999988888*********999888777777765 PP >> tr|B3KU92|B3KU92_HUMAN Putative protein arginine N-methyltransferase 10 OS=Homo sapiens GN=LOC90826 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.4 0.0 0.0081 4.2 1 36 [. 69 103 .. 69 133 .. 0.82 Alignments for each domain: == domain 1 score: 10.4 bits; conditional E-value: 0.0081 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaieda 36 L+iG+GtG l++ ++ +++++++s+ + e a tr|B3KU92|B3KU92_HUMAN 69 LDIGAGTGILSMFAKKA-GAHSVYACELSKTMYELA 103 8*******999999999.556666*****9998555 PP >> tr|B7U632|B7U632_HUMAN PRMT2 gamma variant OS=Homo sapiens GN=PRMT2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.0 0.0022 1.2 1 70 [. 142 208 .. 142 216 .. 0.69 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 0.0022 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvv 70 L++GcGtG ++ ++ + ++ +++v+ s+ a ++ + +++ ++ +++ +++++d ++++Dv tr|B7U632|B7U632_HUMAN 142 LDVGCGTGIISLFCAHYARPRAVYAVEASEMAQ-HTGQLVLQNGF--ADIITVYQQKVEDVVLPEKVDVL 208 8****************9***********9998.44444444443..33344444333333344466665 PP >> tr|H3BSS9|H3BSS9_HUMAN Protein arginine N-methyltransferase 7 (Fragment) OS=Homo sapiens GN=PRMT7 PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 0.0 0.0026 1.4 1 44 [. 69 110 .. 69 134 .. 0.79 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 0.0026 Methyltransf_12 1 LeiGcGtGsllralleklpdieyt.gvDispsaiedakeklakre 44 L+iG+GtG l+++ + +++++ ++++ + + da+ k+ +++ tr|H3BSS9|H3BSS9_HUMAN 69 LDIGTGTGLLSMMAVTA--GADFCyAIEVFKPMA-DAAVKIVEKN 110 8****************..99999899*999999.6666655544 PP >> sp|Q6P2P2|ANM10_HUMAN Putative protein arginine N-methyltransferase 10 OS=Homo sapiens GN=PRMT10 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.1 0.0 0.0097 5.1 1 36 [. 182 216 .. 182 245 .. 0.81 Alignments for each domain: == domain 1 score: 10.1 bits; conditional E-value: 0.0097 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaieda 36 L+iG+GtG l++ ++ +++++++s+ + e a sp|Q6P2P2|ANM10_HUMAN 182 LDIGAGTGILSMFAKKA-GAHSVYACELSKTMYELA 216 8*******999999999.556666*****9998555 PP >> tr|K7ERS2|K7ERS2_HUMAN Methyltransferase-like protein 23 OS=Homo sapiens GN=METTL23 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 0.0 0.0035 1.9 1 96 [. 27 123 .. 27 126 .. 0.74 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 0.0035 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.........ssfDvvvasnvlhh 78 LeiG+G++ ++ ++e++ +D s+ + ++++++ +nl +l++ l g D+++as+v+ tr|K7ERS2|K7ERS2_HUMAN 27 LEIGAGVSLPGILAAKC--GAEVILSDSSELPH------CLEVCRQSCQMNNLPHLQVVGLTWGhiswdllalPPQDIILASDVFFE 105 8*******888888888..**********9776......333333344444555555444444455555555669999********* PP Methyltransf_12 79 lkdirealdniyklLkpg 96 +d +++l+ iy l+ ++ tr|K7ERS2|K7ERS2_HUMAN 106 PEDFEDILATIYFLMHKN 123 *********999888765 PP >> tr|A8MXR3|A8MXR3_HUMAN Protein arginine N-methyltransferase 2 OS=Homo sapiens GN=PRMT2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 0.0 0.0026 1.4 1 70 [. 142 208 .. 142 217 .. 0.69 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 0.0026 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvv 70 L++GcGtG ++ ++ + ++ +++v+ s+ a ++ + +++ ++ +++ +++++d ++++Dv tr|A8MXR3|A8MXR3_HUMAN 142 LDVGCGTGIISLFCAHYARPRAVYAVEASEMAQ-HTGQLVLQNGF--ADIITVYQQKVEDVVLPEKVDVL 208 8****************9***********9998.44444444443..33344444333333344466665 PP >> tr|H3BPG7|H3BPG7_HUMAN Anamorsin OS=Homo sapiens GN=CIAPIN1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.8 0.0 0.0029 1.5 52 99 .] 41 93 .. 15 93 .. 0.71 Alignments for each domain: == domain 1 score: 11.8 bits; conditional E-value: 0.0029 Methyltransf_12 52 nlealdlldldgg....ssfDvvvasnvlhhl.kdirealdniyklLkpgGrl 99 ++ ++++ +l + ssfD++++ v + + +e+l++i++ L+pgG+l tr|H3BPG7|H3BPG7_HUMAN 41 RVSVENIKQLLQSahkeSSFDIILSGLVPGSTtLHSAEILAEIARILRPGGCL 93 333333333332244559******9999988878888**************97 PP >> sp|P55345-3|ANM2_HUMAN Isoform 3 of Protein arginine N-methyltransferase 2 OS=Homo sapiens GN=PRMT2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 0.0 0.0037 1.9 1 70 [. 142 208 .. 142 228 .. 0.72 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 0.0037 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvv 70 L++GcGtG ++ ++ + ++ +++v+ s+ a ++ + +++ ++ +++ +++++d ++++Dv sp|P55345-3|ANM2_HUMAN 142 LDVGCGTGIISLFCAHYARPRAVYAVEASEMAQ-HTGQLVLQNGF--ADIITVYQQKVEDVVLPEKVDVL 208 8****************9***********9998.44444444443..33444444444333344466665 PP >> sp|Q9UBP6|TRMB_HUMAN tRNA (guanine-N(7)-)-methyltransferase OS=Homo sapiens GN=METTL1 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 0.0 0.0038 2 2 42 .. 82 122 .. 81 146 .. 0.79 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 0.0038 Methyltransf_12 2 eiGcGtGsllralleklpdieytgvDispsaiedakeklak 42 +iGcG G ll +l + +pd+ ++g++i ++ + + ++++ sp|Q9UBP6|TRMB_HUMAN 82 DIGCGYGGLLVELSPLFPDTLILGLEIRVKVSDYVQDRIRA 122 8****************999999999887777555555554 PP >> tr|K7EJ00|K7EJ00_HUMAN Methyltransferase-like protein 23 OS=Homo sapiens GN=METTL23 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.0 0.0042 2.2 1 96 [. 27 123 .. 27 126 .. 0.73 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 0.0042 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.........ssfDvvvasnvlhh 78 LeiG+G++ ++ ++e++ +D s+ + ++++++ +nl +l++ l g D+++as+v+ tr|K7EJ00|K7EJ00_HUMAN 27 LEIGAGVSLPGILAAKC--GAEVILSDSSELPH------CLEVCRQSCQMNNLPHLQVVGLTWGhiswdllalPPQDIILASDVFFE 105 89******888888888..**********9776......333333344444555555444444455555555669999********* PP Methyltransf_12 79 lkdirealdniyklLkpg 96 +d +++l+ iy l+ ++ tr|K7EJ00|K7EJ00_HUMAN 106 PEDFEDILATIYFLMHKN 123 *********999888765 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (99 nodes) Target sequences: 88473 (35070517 residues searched) Passed MSV filter: 2562 (0.028958); expected 1769.5 (0.02) Passed bias filter: 2434 (0.0275112); expected 1769.5 (0.02) Passed Vit filter: 374 (0.00422728); expected 88.5 (0.001) Passed Fwd filter: 168 (0.00189888); expected 0.9 (1e-05) Initial search space (Z): 88473 [actual number of targets] Domain search space (domZ): 168 [number of targets reported over threshold] # CPU time: 0.62u 0.03s 00:00:00.65 Elapsed: 00:00:00.26 # Mc/sec: 13353.77 // [ok]