# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/Methyltransf_12.hmm.txt # target sequence database: proteomes/Tetrahymena_thermophila.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: Methyltransf_12 [M=99] Accession: PF08242.11 Description: Methyltransferase domain Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.5e-15 58.3 0.1 5.9e-15 56.4 0.1 2.1 1 tr|Q235D9|Q235D9_TETTS Ubiquinone biosynthesis O-methyltrans 2.7e-15 57.4 0.0 5.8e-15 56.4 0.0 1.6 1 tr|Q24E29|Q24E29_TETTS UbiE/COQ5 family methyltransferase OS 5.4e-13 50.1 0.0 3.7e-12 47.4 0.0 2.3 1 tr|Q23PZ6|Q23PZ6_TETTS Cyclopropane-fatty-acyl-phospholipid 9.2e-13 49.3 0.0 1.4e-12 48.8 0.0 1.3 1 tr|I7MAE9|I7MAE9_TETTS UbiE/COQ5 family methyltransferase OS 1.4e-12 48.7 0.0 1.7e-11 45.2 0.0 2.5 2 tr|I7M0Y7|I7M0Y7_TETTS Embryo-abundant protein, putative OS= 3.5e-12 47.5 0.8 2.2e-11 44.9 0.0 2.1 2 tr|W7X2L6|W7X2L6_TETTS 2-methoxy-6-polyprenyl-1,4-benzoquino 1.1e-11 45.8 0.5 3e-11 44.5 0.1 1.9 1 tr|Q22BT0|Q22BT0_TETTS RNA cap guanine-N2 methyltransferase 1.8e-11 45.2 0.0 3.3e-11 44.4 0.0 1.4 1 tr|W7X0Z1|W7X0Z1_TETTS UbiE/COQ5 methyltransferase, putative 2.2e-11 44.9 0.0 3.6e-11 44.2 0.0 1.3 1 tr|Q239D4|Q239D4_TETTS Cyclopropane-fatty-acyl-phospholipid 1.2e-10 42.5 0.0 2.7e-10 41.4 0.0 1.6 1 tr|Q245D9|Q245D9_TETTS UbiE/COQ5 family methyltransferase OS 1.9e-10 41.9 0.1 5.3e-10 40.5 0.0 1.8 1 tr|Q22D66|Q22D66_TETTS UbiE/COQ5 methyltransferase OS=Tetrah 1.9e-10 41.9 0.0 4.1e-10 40.8 0.0 1.6 1 tr|W7XIC4|W7XIC4_TETTS UbiE/COQ5 methyltransferase OS=Tetrah 2.5e-10 41.5 0.0 5.9e-10 40.3 0.0 1.7 1 tr|Q23EY2|Q23EY2_TETTS UbiE/COQ5 methyltransferase OS=Tetrah 1.5e-09 39.0 0.0 4.8e-09 37.4 0.0 1.9 1 tr|Q23VZ1|Q23VZ1_TETTS UbiE/COQ5 methyltransferase OS=Tetrah 4.8e-09 37.4 0.0 2.2e-08 35.3 0.0 2.2 1 tr|Q23BV8|Q23BV8_TETTS Methyltransferase-like protein OS=Tet 9.4e-09 36.5 0.1 2.8e-08 35.0 0.0 1.9 1 tr|Q24E30|Q24E30_TETTS UbiE/COQ5 methyltransferase OS=Tetrah 1.9e-07 32.3 0.0 3.1e-07 31.6 0.0 1.3 1 tr|I7M351|I7M351_TETTS Kinase domain protein OS=Tetrahymena 1.9e-07 32.3 0.4 0.00083 20.6 0.0 3.6 2 tr|Q22Z04|Q22Z04_TETTS Methyltransferase domain protein OS=T 2.2e-07 32.1 0.0 3.1e-07 31.6 0.0 1.2 1 tr|I7LWQ0|I7LWQ0_TETTS Kinase domain protein OS=Tetrahymena 2.5e-07 31.9 0.9 3.5e-07 31.4 0.0 1.7 1 tr|I7M2L9|I7M2L9_TETTS Methyltransferase OS=Tetrahymena ther 5.9e-07 30.7 0.0 1e-06 29.9 0.0 1.4 1 tr|I7MK94|I7MK94_TETTS AdoMet-dependent proline di-methyltra 6.7e-07 30.5 0.0 1.1e-06 29.8 0.0 1.4 1 tr|I7MD03|I7MD03_TETTS Methyltransferase domain protein OS=T 1.5e-06 29.4 0.0 1.5e-06 29.4 0.0 3.4 1 tr|Q23A13|Q23A13_TETTS UbiE/COQ5 family methyltransferase OS 2.8e-06 28.5 0.1 8.6e-06 27.0 0.0 1.9 1 tr|Q24DN2|Q24DN2_TETTS Alkylated DNA repair alkB-like protei 5.1e-06 27.7 0.0 9.5e-06 26.8 0.0 1.4 1 tr|Q22YS4|Q22YS4_TETTS Ubiquinone/menaquinone biosynthesis m 1.4e-05 26.3 0.0 5.4e-05 24.4 0.0 2.1 1 tr|I7LWZ1|I7LWZ1_TETTS Protein arginine methyltransferase ND 1.4e-05 26.3 0.8 3.1e-05 25.2 0.0 2.0 1 tr|I7LTA0|I7LTA0_TETTS Methyltransferase domain protein OS=T 1.6e-05 26.1 4.8 2.2e-05 25.7 0.0 2.9 1 tr|Q24GH8|Q24GH8_TETTS rRNA adenine N(6)-methyltransferase O 1.7e-05 26.1 0.6 0.00095 20.4 0.2 5.0 3 tr|Q234L5|Q234L5_TETTS mRNA capping enzyme, large subunit fa 2.1e-05 25.7 0.4 0.00032 21.9 0.0 2.9 2 tr|I7M6W8|I7M6W8_TETTS Methyltransferase domain protein OS=T 2.2e-05 25.7 1.2 7.2e-05 24.0 0.2 2.3 1 tr|Q22RB9|Q22RB9_TETTS Methyltransferase domain protein OS=T 2.5e-05 25.5 0.0 0.0046 18.2 0.0 2.8 1 tr|Q23M72|Q23M72_TETTS UbiE/COQ5 family methyltransferase OS 2.6e-05 25.5 0.0 4e-05 24.8 0.0 1.3 1 tr|Q24D55|Q24D55_TETTS Ribosomal protein L11 methyltransfera 2.9e-05 25.3 0.0 8.1e-05 23.8 0.0 1.8 1 tr|I7M6M7|I7M6M7_TETTS Methyltransferase domain protein OS=T 3.4e-05 25.1 5.2 8.8e-05 23.7 0.0 3.1 3 tr|Q22CT3|Q22CT3_TETTS Small ribosomal subunit Rsm22 OS=Tetr 3.8e-05 24.9 0.1 3.8e-05 24.9 0.1 5.0 3 tr|I7MI07|I7MI07_TETTS UbiE/COQ5 family methyltransferase OS 7.1e-05 24.0 0.3 0.00031 22.0 0.1 2.2 1 sp|Q230X8|HENMT_TETTS Small RNA 2'-O-methyltransferase OS=T 0.00012 23.3 0.0 0.00012 23.3 0.0 4.4 1 tr|I7MDV1|I7MDV1_TETTS UbiE/COQ5 family methyltransferase OS 0.00017 22.8 0.0 0.00017 22.8 0.0 3.9 1 tr|Q231D4|Q231D4_TETTS mRNA cap guanine-N7 methyltransferase 0.00037 21.7 0.3 0.0019 19.5 0.2 2.2 1 tr|W7XCF3|W7XCF3_TETTS HemK methyltransferase family protein 0.00054 21.2 0.0 0.0013 20.0 0.0 1.7 1 tr|I7M0P5|I7M0P5_TETTS S-adenosylmethionine-dependent methyl 0.00067 20.9 0.0 0.0014 19.9 0.0 1.6 1 tr|I7M1Y0|I7M1Y0_TETTS Protein-L-isoaspartate O-methyltransf 0.001 20.3 1.2 0.0094 17.2 0.0 2.5 2 tr|Q23MB9|Q23MB9_TETTS tRNA (guanine-N(7)-)-methyltransferas 0.0011 20.3 0.0 0.0018 19.5 0.0 1.4 1 tr|Q24D56|Q24D56_TETTS UbiE/COQ5 methyltransferase, putative 0.002 19.4 1.2 0.0058 17.9 0.0 2.2 1 tr|W7X1L8|W7X1L8_TETTS AdoMet-dependent proline di-methyltra 0.0021 19.3 0.0 0.0021 19.3 0.0 2.7 2 tr|I7MKV3|I7MKV3_TETTS Arginine N-methyltransferase OS=Tetra 0.0057 17.9 0.1 0.0057 17.9 0.1 2.3 1 tr|Q236L4|Q236L4_TETTS L-isoaspartate O-methyltransferase OS ------ inclusion threshold ------ 0.018 16.4 0.0 0.047 15.0 0.0 1.8 1 tr|Q231Q8|Q231Q8_TETTS SAM-dependent methyltransferase OS=Te 0.022 16.1 0.0 0.065 14.5 0.0 1.9 1 tr|Q22SV4|Q22SV4_TETTS Ribosomal protein L11 methyltransfera 0.025 15.9 1.3 7.3 8.0 0.1 3.3 2 tr|W7XFN0|W7XFN0_TETTS Kinase domain protein OS=Tetrahymena 0.04 15.2 0.1 0.15 13.4 0.1 2.0 1 tr|Q23EX7|Q23EX7_TETTS Methyltransferase small domain protei 0.049 14.9 3.0 0.14 13.5 0.6 3.3 1 tr|Q236M3|Q236M3_TETTS Transmembrane protein, putative OS=Te 0.056 14.7 0.0 0.15 13.3 0.0 1.7 1 tr|I7M9J8|I7M9J8_TETTS NOL1/NOP2/Sun family protein OS=Tetra 0.057 14.7 22.3 0.13 13.6 0.1 4.9 2 tr|Q23GA7|Q23GA7_TETTS Bicoid-interacting protein OS=Tetrahy 0.059 14.7 0.3 0.11 13.8 0.2 1.5 1 tr|I7M290|I7M290_TETTS Uncharacterized protein OS=Tetrahymen 0.082 14.2 0.1 0.32 12.3 0.0 2.0 1 tr|Q24FF7|Q24FF7_TETTS Methyltransferase OS=Tetrahymena ther 0.15 13.3 0.1 2.8 9.3 0.1 2.9 2 tr|Q23AQ0|Q23AQ0_TETTS Tetratricopeptide repeat protein OS=T 0.21 12.9 2.6 14 7.1 0.1 3.3 3 tr|W7X6G9|W7X6G9_TETTS Uncharacterized protein OS=Tetrahymen 0.24 12.7 4.5 0.27 12.6 0.0 3.5 2 tr|I7MMN8|I7MMN8_TETTS UPF0586 C9orf41-like protein, putativ 0.28 12.5 1.4 95 4.4 0.0 4.4 3 tr|Q235Z8|Q235Z8_TETTS Kinase domain protein, putative OS=Te 0.38 12.1 1.3 1.8 9.9 0.3 2.3 2 tr|Q23YT4|Q23YT4_TETTS EF-1 guanine nucleotide exchange doma 1.2 10.4 5.5 1.6 10.1 0.0 3.2 3 tr|Q22Z09|Q22Z09_TETTS 16S rRNA methyltransferase OS=Tetrahy 1.5 10.2 3.5 1.3 10.3 0.1 2.8 1 tr|I7MLP7|I7MLP7_TETTS Heat shock-binding protein 70, ER lum 6.1 8.2 0.0 6.1 8.2 0.0 3.5 1 tr|Q231G1|Q231G1_TETTS U6 small nuclear RNA (adenine-(43)-N( Domain annotation for each sequence (and alignments): >> tr|Q235D9|Q235D9_TETTS Ubiquinone biosynthesis O-methyltransferase, mitochondrial OS=Tetrahymena thermophila (strain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 56.4 0.1 1.4e-17 5.9e-15 1 99 [] 409 505 .. 409 505 .. 0.81 Alignments for each domain: == domain 1 score: 56.4 bits; conditional E-value: 1.4e-17 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.ssfDvvvasnvlhhlkdireal 86 L++GcG G l++ l++ ++++tg+D ++++i ++ ++k ++ +++n++ +++l ++ ++D+v++ +v++h++d+++++ tr|Q235D9|Q235D9_TETTS 409 LDVGCGGGLLSESLCRL--GANVTGLDANENSI-SIANNHKKLDQFLEQKLNYKLGTAEELSSQnIQYDLVTCMEVIEHIQDKEQFI 492 8****************..**************.44444444444455555555555555555456********************* PP Methyltransf_12 87 dniyklLkpgGrl 99 + + +l++pgG++ tr|Q235D9|Q235D9_TETTS 493 ATLSQLVRPGGMI 505 ***********86 PP >> tr|Q24E29|Q24E29_TETTS UbiE/COQ5 family methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTH # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 56.4 0.0 1.4e-17 5.8e-15 1 98 [. 47 152 .. 47 153 .. 0.87 Alignments for each domain: == domain 1 score: 56.4 bits; conditional E-value: 1.4e-17 Methyltransf_12 1 LeiGcGtGsllrallekl.pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg........ssfDvvvasnvlhh 78 Le+G+GtG l ++l++ ++++y+++Dis++++ + k k e + n+ +n+e+ +l ++ + +sfD + + +lh tr|Q24E29|Q24E29_TETTS 47 LEVGAGTGFLYNHILNYKkQTAKYVATDISEKML-QIMSKRLKLEYKENQVNNYEKYNLTIQKANaeqlpfeqESFDCLIGNLCLHI 132 8****************989**************.44445555566677777777777777777778999***************** PP Methyltransf_12 79 lkdirealdniyklLkpgGr 98 ++d+ ++l++ y++L +gG+ tr|Q24E29|Q24E29_TETTS 133 TPDPVKMLSESYRVLQKGGV 152 *******************7 PP >> tr|Q23PZ6|Q23PZ6_TETTS Cyclopropane-fatty-acyl-phospholipid synthase OS=Tetrahymena thermophila (strain SB210) OX=31 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 47.4 0.0 8.7e-15 3.7e-12 1 99 [] 155 253 .. 155 253 .. 0.85 Alignments for each domain: == domain 1 score: 47.4 bits; conditional E-value: 8.7e-15 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhlkdireald 87 Le+G+G G l ++ ++l + e gvD+s+++i + + +++++ ++ + + +ald + + +++sfDv++ + h+ + +++++ tr|Q23PZ6|Q23PZ6_TETTS 155 LEVGSGRGGGLNYISRYLNPQECFGVDFSENQIRFCRHHYSQNKKLQFFKGDSQALDQIPEIQENSFDVAINVESSHCYGNFDQFIQ 241 8********************************6677777766666666655555555555444*********************** PP Methyltransf_12 88 niyklLkpgGrl 99 +i ++LkpgG + tr|Q23PZ6|Q23PZ6_TETTS 242 QINRALKPGGFF 253 **********75 PP >> tr|I7MAE9|I7MAE9_TETTS UbiE/COQ5 family methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTH # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 48.8 0.0 3.3e-15 1.4e-12 1 99 [] 56 152 .. 56 152 .. 0.95 Alignments for each domain: == domain 1 score: 48.8 bits; conditional E-value: 3.3e-15 Methyltransf_12 1 LeiGcGtGsllrallekl.pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhlkdireal 86 L++G GtG+ l + +++ + +++tg+Di+++ i++ak+ ++k++n + +n+ + + +++ ++Dv++ s+ + ++d+ +al tr|I7MAE9|I7MAE9_TETTS 56 LDVGVGTGHPLYSIIDRIpKSVQVTGIDIDTNYIPAAKKIFSKHSNVEIKYMNFYDMEKEKTL---KYDVIIFSSSFMLMPDRIKAL 139 8*****************779*************************99999999999866654...9******************** PP Methyltransf_12 87 dniyklLkpgGrl 99 + +++lL+++G++ tr|I7MAE9|I7MAE9_TETTS 140 EIAKNLLADNGKI 152 ***********86 PP >> tr|I7M0Y7|I7M0Y7_TETTS Embryo-abundant protein, putative OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHE # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 45.2 0.0 4.1e-14 1.7e-11 1 95 [. 45 142 .. 45 144 .. 0.88 2 ? 0.4 0.0 4 1.7e+03 19 33 .. 192 206 .. 176 219 .. 0.79 Alignments for each domain: == domain 1 score: 45.2 bits; conditional E-value: 4.1e-14 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.......ssfDvvvasnvlhhlk 80 ++i cGtG+ll++l ++ +g+Disp++ie + +k++k++ ++ +v+ ++d+++l + s++D++++ ++lh+++ tr|I7M0Y7|I7M0Y7_TETTS 45 VDIACGTGQLLFELSNH--FKFSLGTDISPKQIEVTNQKIQKKNLQD--RVKAIVCDAHSLSKIsteqglpSKYDLITIGQALHWFD 127 59***************..9999**********99999999988755..9999999988887779999*****************98 PP Methyltransf_12 81 direaldniyklLkp 95 + +++ + ++ +k+ tr|I7M0Y7|I7M0Y7_TETTS 128 TQEFFTEVSRNIMKQ 142 877777777777766 PP == domain 2 score: 0.4 bits; conditional E-value: 4 Methyltransf_12 19 pdieytgvDispsai 33 + y+g+D+s+++ tr|I7M0Y7|I7M0Y7_TETTS 192 LSLGYVGYDFSKEFK 206 5788*******9985 PP >> tr|W7X2L6|W7X2L6_TETTS 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial OS=Tetrahymena thermophila (s # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.8 0.2 3 1.3e+03 48 88 .. 23 67 .. 7 71 .. 0.58 2 ! 44.9 0.0 5.3e-14 2.2e-11 1 99 [] 107 213 .. 107 213 .. 0.94 Alignments for each domain: == domain 1 score: 0.8 bits; conditional E-value: 3 Methyltransf_12 48 nnnvnlealdlldldggssfDv....vvasnvlhhlkdirealdn 88 n+ n+ +++ + + g +++D+ +++v+h ++d+ ++++ tr|W7X2L6|W7X2L6_TETTS 23 NQTQNNTQTNQEANFGYKKVDInqkqSMVNQVFHSVADKYDLMND 67 333333333333344446777755555566888888777666655 PP == domain 2 score: 44.9 bits; conditional E-value: 5.3e-14 Methyltransf_12 1 LeiGcGtGsllrallekl........pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.ssfDvvvasnvlhh 78 L++ +GtG++++++l+k+ +++++t++Di++s++e k++ +++ +nn +++ + +++ l+ + ++fD+ +++ + + tr|W7X2L6|W7X2L6_TETTS 107 LDVAGGTGDIAFRILDKHksrsslnsKNLKVTVLDINESMLEVGKRRALEKSF-SNNDIDFVCGNAEILPFEdNTFDAYTIAYGIRN 192 8****************************************888888888876.78999999999988888899************* PP Methyltransf_12 79 lkdirealdniyklLkpgGrl 99 ++ i++al++++++Lk+gGrl tr|W7X2L6|W7X2L6_TETTS 193 VPRIEKALSEAHRVLKKGGRL 213 *******************97 PP >> tr|Q22BT0|Q22BT0_TETTS RNA cap guanine-N2 methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=T # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 44.5 0.1 7.1e-14 3e-11 1 95 [. 42 139 .. 42 142 .. 0.82 Alignments for each domain: == domain 1 score: 44.5 bits; conditional E-value: 7.1e-14 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrenn.nnnnvnlealdlldldgg....ssfDvvvasnvlhhlkdi 82 L++GcGtG++l++l + +g+Dis++++ a ek+a ++++ n++ ++ +a++++++ ++ s+D+v++ ++lh+++ tr|Q22BT0|Q22BT0_TETTS 42 LDVGCGTGQMLFKLNSH--FKFAVGTDISEKQVSVANEKIANNQEYsNVKVIQCDANNIISSLEKnslpLSYDLVTVGQALHWFEVE 126 8*************999..99999*********999999988776615566788999999998889*****************8544 PP Methyltransf_12 83 realdniyklLkp 95 +++ k Lk+ tr|Q22BT0|Q22BT0_TETTS 127 KFLHLTQSKILKQ 139 4444344566665 PP >> tr|W7X0Z1|W7X0Z1_TETTS UbiE/COQ5 methyltransferase, putative OS=Tetrahymena thermophila (strain SB210) OX=312017 GN= # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 44.4 0.0 7.8e-14 3.3e-11 1 98 [. 46 151 .. 46 152 .. 0.91 Alignments for each domain: == domain 1 score: 44.4 bits; conditional E-value: 7.8e-14 Methyltransf_12 1 LeiGcGtGsllrallekl.pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.......ssfDvvvasnvlhhl 79 Le+G+G G l ++ l++ p+++yt++D+s +++ + ++l+ +++ n +n + + ++++ g ++fD +a+ +l+ + tr|W7X0Z1|W7X0Z1_TETTS 46 LEVGAGAGFLYSHTLNRKkPEAKYTATDVSVKMLYQMCKRLKIEGDLTNGLYNEKYNLAIEKVNGetlpysdGTFDCYIANLCLQLT 132 8**********999999989**************99999999888888777777777766666669********************* PP Methyltransf_12 80 kdirealdniyklLkpgGr 98 +d++++l++ y++L +gG+ tr|W7X0Z1|W7X0Z1_TETTS 133 PDPQKMLNESYRVLQKGGV 151 ******************8 PP >> tr|Q239D4|Q239D4_TETTS Cyclopropane-fatty-acyl-phospholipid synthase OS=Tetrahymena thermophila (strain SB210) OX=31 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 44.2 0.0 8.6e-14 3.6e-11 1 99 [] 54 150 .. 54 150 .. 0.85 Alignments for each domain: == domain 1 score: 44.2 bits; conditional E-value: 8.6e-14 Methyltransf_12 1 LeiGcGtGsllrallekl.pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhlkdireal 86 L+iG GtG l +++ k+ ++++++gvDi+++ +++a++ +++++n n+ +ld+ ++ +++fD+v+ s+ + ++++++a+ tr|Q239D4|Q239D4_TETTS 54 LDIGIGTGLPLYKIASKFpQNAKILGVDIDENYVKAAQKLFKDKKNVEIRLQNFYELDA-KK--EGQFDIVLFSFSFMLMPEREKAI 137 8*****************88**************7777777777766655555555554.33..35********************* PP Methyltransf_12 87 dniyklLkpgGrl 99 + +++l+k++Gr+ tr|Q239D4|Q239D4_TETTS 138 ALAKQLVKKDGRI 150 ***********86 PP >> tr|Q245D9|Q245D9_TETTS UbiE/COQ5 family methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTH # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 41.4 0.0 6.4e-13 2.7e-10 1 99 [] 55 156 .. 55 156 .. 0.82 Alignments for each domain: == domain 1 score: 41.4 bits; conditional E-value: 6.4e-13 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg........ssfDvvvasnvlhhl 79 L+i cGtG+ll+ l ++ + +g+Dis++++ e+l k +n +n+ + ++a + + ++ +fD++++ ++lh++ tr|Q245D9|Q245D9_TETTS 55 LDIACGTGQLLFQLQNH--FEKSIGTDISEKQL-SVVEELIKSNNLSNSVYSIKADC-H-QLPNilqeknlpTKFDLITVGQALHWF 136 8****************..**************.77777777776666666555332.3.333346678899**************7 PP Methyltransf_12 80 kdirealdniy.klLkpgGrl 99 d++ +l+ + +lLkp+G l tr|Q245D9|Q245D9_TETTS 137 -DVHPFLKMVGkDLLKPDGSL 156 .999999999879******76 PP >> tr|Q22D66|Q22D66_TETTS UbiE/COQ5 methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM_009 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 40.5 0.0 1.2e-12 5.3e-10 1 98 [. 47 152 .. 47 153 .. 0.82 Alignments for each domain: == domain 1 score: 40.5 bits; conditional E-value: 1.2e-12 Methyltransf_12 1 LeiGcGtGsllrallekl.pdieytgvDispsai......edakeklakrennnnnnvnlealdlldldgg...ssfDvvvasnvlh 77 Le+G+G+G l ++ ++ ++++y+++D+s++++ + ke ++++ + n+++e+ + ++l + ++fD +a+ +l+ tr|Q22D66|Q22D66_TETTS 47 LEVGAGSGFLFHHTMNYKkSEAKYVATDLSENMLqyilmrLNIKEAFKDKYFISSYNLTIEKANGEEL--PfldGTFDCYIANLCLQ 131 8***************9988**************7777555555555555555555566665554444..15699************ PP Methyltransf_12 78 hlkdirealdniyklLkpgGr 98 ++d++++l++ y++L +gG+ tr|Q22D66|Q22D66_TETTS 132 ITNDPAKMLKESYRVLQKGGV 152 ********************7 PP >> tr|W7XIC4|W7XIC4_TETTS UbiE/COQ5 methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM_000 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 40.8 0.0 9.8e-13 4.1e-10 1 98 [. 72 177 .. 72 178 .. 0.90 Alignments for each domain: == domain 1 score: 40.8 bits; conditional E-value: 9.8e-13 Methyltransf_12 1 LeiGcGtGsllrallekl.pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg........ssfDvvvasnvlhh 78 Le+G+G G l + l++ p+++y+++D+s s++ ++ e + n+ +++ + +l+ ++ + + fD +a+ +l+ tr|W7XIC4|W7XIC4_TETTS 72 LEVGAGGGFLYNHSLNRKhPNSNYYATDLSDSMLGILCKR-IGVEYKPNQLITIPNYNLHIEKANgeklhyknEMFDCYIANLCLQI 157 8***********99999889**************555555.55666899999999999988887799******************** PP Methyltransf_12 79 lkdirealdniyklLkpgGr 98 + +++++++++ ++L pgG tr|W7XIC4|W7XIC4_TETTS 158 TTNPEKMIQEANRVLQPGGY 177 *******************6 PP >> tr|Q23EY2|Q23EY2_TETTS UbiE/COQ5 methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM_006 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 40.3 0.0 1.4e-12 5.9e-10 1 97 [. 67 172 .. 67 174 .. 0.95 Alignments for each domain: == domain 1 score: 40.3 bits; conditional E-value: 1.4e-12 Methyltransf_12 1 LeiGcGtGsllrallekl.pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg........ssfDvvvasnvlhh 78 Le+G+G G ll + l++ p +ey ++D+s+++++ ++++ ++ +n++v + +l ++ + ++fD +++ +l+ tr|Q23EY2|Q23EY2_TETTS 67 LEVGAGGGYLLNHALKYKkPSAEYFATDLSENMLKILCRRMNLQDCLSNQQVSQNLYNLTIQKANgealqyqdDTFDCYISNLCLQL 153 8***************9999***************99999999999999999999999988888899******************** PP Methyltransf_12 79 lkdirealdniyklLkpgG 97 + +++ ++++ y++L +gG tr|Q23EY2|Q23EY2_TETTS 154 TSNPELMIKESYRVLQKGG 172 ******************9 PP >> tr|Q23VZ1|Q23VZ1_TETTS UbiE/COQ5 methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM_007 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 37.4 0.0 1.1e-11 4.8e-09 1 98 [. 56 161 .. 56 162 .. 0.84 Alignments for each domain: == domain 1 score: 37.4 bits; conditional E-value: 1.1e-11 Methyltransf_12 1 LeiGcGtGsllrallekl.pdieytgvDispsaiedakekl.akrennnnnnvnlealdlldldgg......ssfDvvvasnvlhhl 79 Le+G+G G l + l++ p+++y+++Dis s+++ +++ ++ + +++ + + +l++++ g+ ++fD +++ +l+ + tr|Q23VZ1|Q23VZ1_TETTS 56 LEVGAGGGFLYNHSLQRKhPEANYYATDISDSMLDTLCKRMgGQYTPTQTTYIPNYKLHISNANGEqlpfkdETFDCYICNLCLQIT 142 8**********998888779**************5555555156666677777777777766666699999**************** PP Methyltransf_12 80 kdirealdniyklLkpgGr 98 +++++l+++ ++L +gG tr|Q23VZ1|Q23VZ1_TETTS 143 TNPDKMLSEAIRVLQKGGY 161 *****************96 PP >> tr|Q23BV8|Q23BV8_TETTS Methyltransferase-like protein OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM_ # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 35.3 0.0 5.2e-11 2.2e-08 2 98 .. 191 290 .. 190 291 .. 0.80 Alignments for each domain: == domain 1 score: 35.3 bits; conditional E-value: 5.2e-11 Methyltransf_12 2 eiGcGtGsllrallekl.pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg....ssfDvvvasnvlhhl..kd 81 e+GcG+G+++ +l ++ +++++D+s++ai e +k e+++ ++v e+ dl +++ + D+v++++vl+++ ++ tr|Q23BV8|Q23BV8_TETTS 191 ELGCGVGDTIYPLMPQYpAIKKFYVCDFSSKAI----EWVKKAEPYDPEKVVAEVADLVNDPIPaafnPPADIVTLIFVLSAIspEN 273 89***************5577899*********....55555555555555555555544444455569****************** PP Methyltransf_12 82 irealdniyklLkpgGr 98 ++++++i +++kpg + tr|Q23BV8|Q23BV8_TETTS 274 HQKVISKIFEWMKPGSV 290 **************976 PP >> tr|Q24E30|Q24E30_TETTS UbiE/COQ5 methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM_008 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 35.0 0.0 6.6e-11 2.8e-08 1 98 [. 47 152 .. 47 153 .. 0.82 Alignments for each domain: == domain 1 score: 35.0 bits; conditional E-value: 6.6e-11 Methyltransf_12 1 LeiGcGtGsllrallekl.pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg........ssfDvvvasnvlhh 78 Le+G+G G l + + ++++y+++D+s++++ + ++ ++e+ + + + +++ +l ++ + ++fD +a+ +l+ tr|Q24E30|Q24E30_TETTS 47 LEVGAGAGFLFNHTMNFKkHGAQYIATDLSEKML-QYILRRLQIEEPFKDGMLIDKYNLRIQKANgeelpfedNTFDCYIANLCLQI 132 8*******999998777778**************.5555555555555565555555555555555689999*************** PP Methyltransf_12 79 lkdirealdniyklLkpgGr 98 + d+ ++l++ +++L +gG+ tr|Q24E30|Q24E30_TETTS 133 TTDPVKMLKESHRVLQKGGV 152 *******************7 PP >> tr|I7M351|I7M351_TETTS Kinase domain protein OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM_00558360 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 31.6 0.0 7.4e-10 3.1e-07 1 98 [. 45 145 .. 45 146 .. 0.89 Alignments for each domain: == domain 1 score: 31.6 bits; conditional E-value: 7.4e-10 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhl.......k 80 L +G+G+++l++++ ++ + ++t +Dis+ + + +ek +++++ n++ ++ ++++++ ++ +sfD v ++l + tr|I7M351|I7M351_TETTS 45 LNVGSGSSRLSEEMFDE-GHQNITNIDISSIVTKSMQEKYKDKGP-NFKYLQMDVRNMEFEA--KSFDCVMDKGTLDSIlcgesstS 127 789**************.99*************999999999886.6677777777765444..5********************** PP Methyltransf_12 81 direaldniyklLkpgGr 98 + ++a+++iy++L+p G+ tr|I7M351|I7M351_TETTS 128 NANKAISEIYRVLTPKGV 145 ***************997 PP >> tr|Q22Z04|Q22Z04_TETTS Methyltransferase domain protein OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHER # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.6 0.0 2e-06 0.00083 1 96 [. 60 160 .. 60 162 .. 0.86 2 ? 7.3 0.2 0.027 11 2 97 .. 490 620 .. 489 622 .. 0.54 Alignments for each domain: == domain 1 score: 20.6 bits; conditional E-value: 2e-06 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.ssfDvvvasnvlhhl....... 79 L iGcG++ +++ + + +++ +D+s+++i +++++r+++ ++++e+ d+++ +sfD+v ++l ++ tr|Q22Z04|Q22Z04_TETTS 60 LNIGCGNSLFSEDMYDG-GFKNIVNCDFSEDVI----KEMSARSAKIRPEMKYEVVDIFNMTYApNSFDIVMDKGLLDAVypeetee 141 78************999.9**************....66666666666688888888887766678****************99999 PP Methyltransf_12 80 ..kdirealdniyklLkpg 96 +i+++l++i + L+ + tr|Q22Z04|Q22Z04_TETTS 142 ntTKINKFLQSIVDILTAN 160 9889999999999998876 PP == domain 2 score: 7.3 bits; conditional E-value: 0.027 Methyltransf_12 2 eiGcGtGsllrallekl...............pdieyt.gvDispsaiedakeklakrennnnnnvnlealdlldldgg........ 64 +G+G +l++ + +++ + ++++ gvD +p++ + ++ ++n+ +n+ + tr|Q22Z04|Q22Z04_TETTS 490 VLGAGLCALSKFIYNHFantklnnieisknivEAAKIHfGVDKDPRFKITIDNAFSYIKNHTVNEEAP----------Kvekegsei 566 689999999*9999999555555555555554445555555555555434444444444333333333..........133333444 PP Methyltransf_12 65 .............ssfDvvvasnvlhhl........kdirealdniyklLkpgG 97 +++D++v+ v +e+l+++ klL ++G tr|Q22Z04|Q22Z04_TETTS 567 eeakesktapkkkQQYDIIVIDIVSPQEnqasppeqFLQEEFLQKLQKLLENNG 620 557888888888888888886544333333445543333356666666666666 PP >> tr|I7LWQ0|I7LWQ0_TETTS Kinase domain protein OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM_00578720 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 31.6 0.0 7.2e-10 3.1e-07 1 98 [. 45 145 .. 45 146 .. 0.87 Alignments for each domain: == domain 1 score: 31.6 bits; conditional E-value: 7.2e-10 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.ssfDvvvasnvlhhl....... 79 L iG+G++++++++ ++ ++t +Dis+ + ++ +ek +++++ n+++ + d+ + d + +s+D+v+ ++l + tr|I7LWQ0|I7LWQ0_TETTS 45 LNIGAGNSRMSEEMFDE-GYQNITNIDISQVVTKAMQEKYKDKGP----NMKYLCMDVKNMDFPaGSYDIVLDKGTLDSVlcgenta 126 78***************.9999***********888888888886....55666666555555557********************9 PP Methyltransf_12 80 kdirealdniyklLkpgGr 98 + ++al ni ++L+p G+ tr|I7LWQ0|I7LWQ0_TETTS 127 TNAQKALTNISNVLTPTGV 145 99**************997 PP >> tr|I7M2L9|I7M2L9_TETTS Methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM_00305590 PE=4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 31.4 0.0 8.3e-10 3.5e-07 1 98 [. 55 155 .. 55 156 .. 0.95 Alignments for each domain: == domain 1 score: 31.4 bits; conditional E-value: 8.3e-10 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhl........ 79 L+iGcG+G + l e+ + + +g+Dis+++++ a e+ ++ + + + + ++ + fD +++ ++l++l tr|I7M2L9|I7M2L9_TETTS 55 LDIGCGSGLSGAQLSEH--NHHWVGIDISRDMLNVAVERESEGDLYEIDMGQGFNFRHG------VFDSAISVSALQWLcvaskksy 133 8****************..***********************99999999999988865......9********************* PP Methyltransf_12 80 ...kdirealdniyklLkpgGr 98 + ++++++++y+ L+ gG+ tr|I7M2L9|I7M2L9_TETTS 134 npvARLKKFFQSLYNSLRAGGK 155 ********************97 PP >> tr|I7MK94|I7MK94_TETTS AdoMet-dependent proline di-methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=31 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.9 0.0 2.5e-09 1e-06 2 99 .] 103 197 .. 102 197 .. 0.91 Alignments for each domain: == domain 1 score: 29.9 bits; conditional E-value: 2.5e-09 Methyltransf_12 2 eiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhl..kdireal 86 + G+G G++++++l + + +vD +p+ ie+ k+ +++ ++ v++ a l +l+ ++++D +++ v+++l +d ++l tr|I7MK94|I7MK94_TETTS 103 DCGAGMGRITKEFLLH-FFKNADVVDQNPKYIEACKQNFKDDKR----VVHFIAKGLQELEFPEKYDCIWIQWVCNYLtdEDFVKFL 184 78************99.6777779********999999999997....7788888888888889*********************** PP Methyltransf_12 87 dniyklLkpgGrl 99 +++ ++L+++G + tr|I7MK94|I7MK94_TETTS 185 KRCSEALVQNGFI 197 ***********75 PP >> tr|I7MD03|I7MD03_TETTS Methyltransferase domain protein OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHER # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.8 0.0 2.7e-09 1.1e-06 1 98 [. 59 162 .. 59 163 .. 0.88 Alignments for each domain: == domain 1 score: 29.8 bits; conditional E-value: 2.7e-09 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg...ssfDvvvasnvlhhl..... 79 L +GcG++ l++++ + ++t vD+s + i k ++++ + n +++e++d+ + +g+ +sfD v+ ++l + tr|I7MD03|I7MD03_TETTS 59 LNVGCGSSLLSEEMYFE-GYKNITNVDYSNNLI---KHLVERYSEGFENTFKFEHCDVRNMKGKfanNSFDCVIDKGTLDSVlcgey 141 789*********99888.89*************...6666667777778888888888888888888******************** PP Methyltransf_12 80 ..kdirealdniyklLkpgGr 98 ++ ++l++i ++L+++G+ tr|I7MD03|I7MD03_TETTS 142 srQNSFKMLSEISRVLTQDGV 162 988888*************97 PP >> tr|Q23A13|Q23A13_TETTS UbiE/COQ5 family methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTH # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.4 0.0 3.5e-09 1.5e-06 1 98 [. 84 181 .. 84 182 .. 0.84 Alignments for each domain: == domain 1 score: 29.4 bits; conditional E-value: 3.5e-09 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhl......kd 81 L iGcG++ l++ + ++ i+++ +Dis +i ++++++ +++n ++++++ l + + +fD v+ ++l +l + tr|Q23A13|Q23A13_TETTS 84 LMIGCGNSKLSEDMFDD-GYINIVSTDISDVVI----QQMKEQTQKKNMIFEVQDCTNLTYQDQ-TFDFVFDKGTLDALscdkeeQS 164 569**************.9**************....666666666666666655554444443.******************9999 PP Methyltransf_12 82 irealdniyklLkpgGr 98 ++++l+++ +++kp G tr|Q23A13|Q23A13_TETTS 165 VNKMLSEMMRVCKPQGS 181 99************996 PP >> tr|Q24DN2|Q24DN2_TETTS Alkylated DNA repair alkB-like protein, putative OS=Tetrahymena thermophila (strain SB210) OX # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.0 0.0 2e-08 8.6e-06 2 97 .. 248 336 .. 247 338 .. 0.78 Alignments for each domain: == domain 1 score: 27.0 bits; conditional E-value: 2e-08 Methyltransf_12 2 eiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhl..kdir.ea 85 +iGcG+G +l+ ++ di +g+D s++ i a+++ +++ +++ ++l l+ s+fD ++++ v+hh+ +++r a tr|Q24DN2|Q24DN2_TETTS 248 DIGCGNGKYLDC---HNGDIYMIGTDRSENLISLARNRGEDIQVFSADSLKLPWLS-------SKFDNAISIAVIHHFstPELRiHA 324 8******66654...4568*************666666666665555555555555.......5**************887777799 PP Methyltransf_12 86 ldniyklLkpgG 97 +++i + L+ gG tr|Q24DN2|Q24DN2_TETTS 325 IKEILRILRVGG 336 999999999998 PP >> tr|Q22YS4|Q22YS4_TETTS Ubiquinone/menaquinone biosynthesis methyltransferase family protein OS=Tetrahymena thermophi # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.8 0.0 2.3e-08 9.5e-06 11 98 .. 96 176 .. 84 177 .. 0.81 Alignments for each domain: == domain 1 score: 26.8 bits; conditional E-value: 2.3e-08 Methyltransf_12 11 lralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhlkdirealdniyklLkpgG 97 l+ p+++++g+D s++++e+a +k ++ ++ + + e+l d+ fD+vv + l++ ++++al+++++++k++G tr|Q22YS4|Q22YS4_TETTS 96 LKFY---PPGVKVLGIDWSSNMLEAAMQKSVNHISYSYKIDDTENLTFKDN----VFDTVVDTFGLEYYVNPDKALKEMKRVCKKDG 175 3333...2679************9999998888888877777777775544....9******************************9 PP Methyltransf_12 98 r 98 tr|Q22YS4|Q22YS4_TETTS 176 L 176 7 PP >> tr|I7LWZ1|I7LWZ1_TETTS Protein arginine methyltransferase NDUFAF7 OS=Tetrahymena thermophila (strain SB210) OX=31201 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.4 0.0 1.3e-07 5.4e-05 1 59 [. 147 213 .. 147 242 .. 0.83 Alignments for each domain: == domain 1 score: 24.4 bits; conditional E-value: 1.3e-07 Methyltransf_12 1 LeiGcGtGsllrallekl........pdieytgvDispsaiedakeklakrennnnnnvnlealdll 59 +eiG+G +s ++ +l+++ ++eyt v+isp+++++a ekl++ + + ++ +++ ++++ tr|I7LWZ1|I7LWZ1_TETTS 147 VEIGAGQASAAQSILMYFknyeqsyyANLEYTIVEISPQMCKKALEKLSRDHSKLIERGQIKFINDD 213 69***********************************************999888777666666654 PP >> tr|I7LTA0|I7LTA0_TETTS Methyltransferase domain protein OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHER # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.2 0.0 7.3e-08 3.1e-05 1 98 [. 46 145 .. 46 146 .. 0.82 Alignments for each domain: == domain 1 score: 25.2 bits; conditional E-value: 7.3e-08 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhl.......k 80 L +GcG++ + +++ ++ +++ +Dis++ i++ + r + + ++ +l+ +d ++fD v+ +++ +l tr|I7LTA0|I7LTA0_TETTS 46 LNLGCGNSVIQEEMYDD-GYKNIYNIDISEECIKQMDSRKGNRPELIYEVMDCTELKYED----EKFDFVIDKSTIDALlcgdysyL 127 679*****999999999.9999***********555555555555555555555554443....4*******************999 PP Methyltransf_12 81 direaldniyklLkpgGr 98 +++++++++ ++Lkp+G+ tr|I7LTA0|I7LTA0_TETTS 128 NVAKMMSEVQRVLKPNGV 145 9****************7 PP >> tr|Q24GH8|Q24GH8_TETTS rRNA adenine N(6)-methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TT # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.7 0.0 5.1e-08 2.2e-05 1 73 [. 44 111 .. 44 124 .. 0.90 Alignments for each domain: == domain 1 score: 25.7 bits; conditional E-value: 5.1e-08 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvas 73 LeiG GtG+l++ llek ++++v+i+p+++ a++ +++ +++++++l + d+++++ + fDv va+ tr|Q24GH8|Q24GH8_TETTS 44 LEIGPGTGNLTALLLEK--AKKVIAVEIDPRMV--AELNKRFKYSQHAHKFELIQGDAISTEFP-FFDVCVAN 111 8****************..**************..77777777778999********9999988.89998876 PP >> tr|Q234L5|Q234L5_TETTS mRNA capping enzyme, large subunit family protein OS=Tetrahymena thermophila (strain SB210) O # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.1 1.9 1.1 4.8e+02 39 57 .. 168 186 .. 159 211 .. 0.55 2 ! 12.5 0.0 0.00064 0.27 1 40 [. 326 365 .. 326 385 .. 0.84 3 ! 20.4 0.2 2.3e-06 0.00095 42 99 .] 458 519 .. 408 519 .. 0.87 Alignments for each domain: == domain 1 score: 2.1 bits; conditional E-value: 1.1 Methyltransf_12 39 klakrennnnnnvnleald 57 + ++++nnnnn +n+ +l+ tr|Q234L5|Q234L5_TETTS 168 RRQHNNNNNNNSNNNSNLN 186 3333333333333333333 PP == domain 2 score: 12.5 bits; conditional E-value: 0.00064 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakekl 40 L++ cG G +++l++ + + y+gvDi +a+++a ++ tr|Q234L5|Q234L5_TETTS 326 LDLACGKGGDHKKWLMHSHACFYIGVDIAMEALNQAYQRA 365 89*******************************7776664 PP == domain 3 score: 20.4 bits; conditional E-value: 2.3e-06 Methyltransf_12 42 krennnnnnvnlealdlldldggssfDvvvasnvlhhl....kdirealdniyklLkpgGrl 99 +++++ +n++ e++++ ++ g+ fDvv + ++h++ +++r +ldn+ k L++ G l tr|Q234L5|Q234L5_TETTS 458 GQSPKKEENNEKEQNKDKEQYGKYMFDVVSCQMAMHYMheseEKVRNFLDNCTKRLNDQGFL 519 45566677778888888888888***********************************9976 PP >> tr|I7M6W8|I7M6W8_TETTS Methyltransferase domain protein OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHER # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.2 0.1 4.5 1.9e+03 40 71 .. 193 225 .. 148 227 .. 0.67 2 ! 21.9 0.0 7.6e-07 0.00032 1 98 [. 235 336 .. 235 337 .. 0.81 Alignments for each domain: == domain 1 score: 0.2 bits; conditional E-value: 4.5 Methyltransf_12 40 lakrennnnnnvnlealdlldldgg....ssfDvvv 71 +r+ n+n++++ ++ d + + ++fD+v+ tr|I7M6W8|I7M6W8_TETTS 193 QIQRNLNKNKQMDTQTYDQSR---PaippQHFDMVL 225 333344444555555554333...245588888875 PP == domain 2 score: 21.9 bits; conditional E-value: 7.6e-07 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsai....edakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhlkdir 83 L++G tG++ + + + + +++g+D++++ + ++a++ l + n+++ ++ ++ +++d+ ++++fD+v++ + +h++ ++ tr|I7M6W8|I7M6W8_TETTS 235 LDLGMETGQNFFQFYHQ-FNGNIVGIDLNSQRVefvrQKAQKILPTQAINRTQLIDGDVFKIADKLPNKTFDLVTIGSQIHNFGSPD 320 89999999999999888.799************66666666666666777777777777777888777***************9999 PP Methyltransf_12 84 ealdniy.klLkpgGr 98 ++ + ++ +lL+ +G tr|I7M6W8|I7M6W8_TETTS 321 KFYQFAKeRLLSAEGT 336 9999877677777775 PP >> tr|Q22RB9|Q22RB9_TETTS Methyltransferase domain protein OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHER # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.0 0.2 1.7e-07 7.2e-05 1 98 [. 102 219 .. 102 220 .. 0.77 Alignments for each domain: == domain 1 score: 24.0 bits; conditional E-value: 1.7e-07 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg....................... 64 +++GcG G l + ++ ++++ D++ +++ + +l+ + n +v + ++ l+ l g+ tr|Q22RB9|Q22RB9_TETTS 102 MDLGCGHGLLGIYAMQQ-GAKQVLFQDYNYEVL-SIAVRLNIILN----KVPNVQERLIYLSGEwnnlenkiaqqinevgflenkiv 182 69***********9999.778888999999999.44444443332....33333333333333344566777777788888****** PP Methyltransf_12 65 ...ssfDvvvasnvlhhlkdirealdniyklLkpgGr 98 ++fD+ +s+v+ + ++ +++ + iykl+kp+G+ tr|Q22RB9|Q22RB9_TETTS 183 qyeNQFDILMLSEVIYNQANYEKVTNLIYKLMKPNGI 219 ************************************7 PP >> tr|Q23M72|Q23M72_TETTS UbiE/COQ5 family methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTH # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.2 0.0 1.1e-05 0.0046 1 99 [] 126 279 .. 126 279 .. 0.79 Alignments for each domain: == domain 1 score: 18.2 bits; conditional E-value: 1.1e-05 Methyltransf_12 1 LeiGcGtGsllrallekl.pdieytgvDispsai..edakeklakrennnnnnvnle.aldlldldgg................... 64 Le GcGt +l +l + +++++ +Dis+ + ++k+kl + ++ +++ ++++ + ++ ++d + tr|Q23M72|Q23M72_TETTS 126 LECGCGTEYILPYLVQMKkKQCKLFLTDISKVKLsvIKHKLKLLEVNPLSTKLYDYNfVPNM-EEDWQeqdklhtncikndgqelcd 211 78899999999998887778999999999999884434444444444444444433202332.222225788899999999999999 PP Methyltransf_12 65 .................................ssfDvvvasnvlhhlkdirealdniyklLkpgGrl 99 s fD+ + +++ +kd+ +a++++y++Lk+gGr+ tr|Q23M72|Q23M72_TETTS 212 niqeqvkssglyfnkglnvfaeradatklfyanSVFDIYFGGMLINEVKDPFQAIKEAYRVLKKGGRV 279 999999999999999999999999999999**99********************************85 PP >> tr|Q24D55|Q24D55_TETTS Ribosomal protein L11 methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 G # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.8 0.0 9.4e-08 4e-05 1 98 [. 62 159 .. 62 160 .. 0.89 Alignments for each domain: == domain 1 score: 24.8 bits; conditional E-value: 9.4e-08 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.ssfDvvvasnvlhhlkdireal 86 Le+G+G+G a l++++ ++ +D++++++ + +k ++++ + ++++++ l+ ++ d+ +++Dv++ s+ + + ++e+ tr|Q24D55|Q24D55_TETTS 62 LEVGTGVGIGGLAALKYTECKRVDMTDYNQDVL-ANIKKNSEKNSISKQRYDVFYLNWFEYDKFnKKYDVIIGSDIIYSGAPLKELY 147 8********************************.55555555555688999999999999988899***********9999*****9 PP Methyltransf_12 87 dniyklLkpgGr 98 i k L++gG+ tr|Q24D55|Q24D55_TETTS 148 LLISKSLNKGGK 159 999999999996 PP >> tr|I7M6M7|I7M6M7_TETTS Methyltransferase domain protein OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHER # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.8 0.0 1.9e-07 8.1e-05 1 75 [. 84 169 .. 84 195 .. 0.85 Alignments for each domain: == domain 1 score: 23.8 bits; conditional E-value: 1.9e-07 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvD..ispsaiedakeklakrennnnnnvnlealdlldldgg...........ssfDvvvasn 74 Le+GcGtG l+ l+ + +++++++D i ++ +e+ + ++ + + v++ ald +++++ ++ D++vas+ tr|I7M6M7|I7M6M7_TETTS 84 LELGCGTGCLSIFLASQ--GANVVATDlkITQNYVEKNLQMNKELVDCRQGTVKFVALDWNEQEEKifqilksdigfQKIDYIVASD 168 8****************..999999993345666799999999999999999*******9999999******************996 PP Methyltransf_12 75 v 75 + tr|I7M6M7|I7M6M7_TETTS 169 T 169 5 PP >> tr|Q22CT3|Q22CT3_TETTS Small ribosomal subunit Rsm22 OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM_0 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.1 5.8 2.4e+03 37 92 .. 32 93 .. 15 96 .. 0.59 2 ? 0.5 1.4 3.7 1.6e+03 35 70 .. 165 200 .. 155 204 .. 0.79 3 ! 23.7 0.0 2.1e-07 8.8e-05 1 98 [. 264 362 .. 264 363 .. 0.76 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 5.8 Methyltransf_12 37 keklakrennnnnnvnlealdlldldgg.....ssfDvvvas.nvlhhlkdirealdniykl 92 ++kl++++++ ++ ++e l+d++++ + D +++ + l + + +++al+++ ++ tr|Q22CT3|Q22CT3_TETTS 32 SQKLNEKKKKTEEQKKIEGAILHDKESRkekdsEEIDQLFMAkCHLDVQRFPEKALKRAQQV 93 44444444444444444444444444444566678999988844455546677777776665 PP == domain 2 score: 0.5 bits; conditional E-value: 3.7 Methyltransf_12 35 dakeklakrennnnnnvnlealdlldldggssfDvv 70 + k+kl++++++nn+ + +++++ ++ +++s D+v tr|Q22CT3|Q22CT3_TETTS 165 KLKRKLKAEKAQNNKDEETQQEKDQNSTEQESDDLV 200 568899999999999999999998888777776665 PP == domain 3 score: 23.7 bits; conditional E-value: 2.1e-07 Methyltransf_12 1 LeiGcGtGsllrallekl.pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhl...kdir 83 L++G+G Gs + a+ + + + +++++++s+++ + +++ + ++n + nl ++ +l+ fD+v++s+vl+ + + ++ tr|Q22CT3|Q22CT3_TETTS 264 LDFGAGLGSGSLAFQDIFpECKNIVACEPSKNMR-KLGKHMTQDIPNLVYVENLAQTI--SLPYAVEFDIVFISHVLQEVpsvEARK 347 8*************99996688889*********.55555555554333333333333..233337**************9988888 PP Methyltransf_12 84 ealdniyklLkpgGr 98 ++d++ + +k+gG+ tr|Q22CT3|Q22CT3_TETTS 348 LIIDSLWNKVKKGGI 362 999999999999996 PP >> tr|I7MI07|I7MI07_TETTS UbiE/COQ5 family methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTH # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.9 0.1 9.1e-08 3.8e-05 1 98 [. 218 308 .. 218 309 .. 0.75 2 ? -0.6 0.3 8 3.4e+03 50 79 .. 408 452 .. 385 478 .. 0.56 3 ? -0.7 0.4 8.5 3.6e+03 35 64 .. 497 526 .. 488 566 .. 0.70 Alignments for each domain: == domain 1 score: 24.9 bits; conditional E-value: 9.1e-08 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsai...edakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhlkdire 84 L++GcG+++++ ++++l +++gvD + + ++ + + n nn++nl + + +D+v+++ ++hh+++++ tr|I7MI07|I7MI07_TETTS 218 LDVGCGNAEISVTIAQNLGIGSVYGVDMFDEDDfvqPSMDLEVKYLQ-NLNNKLNLPN---------NCVDLVTCFMAIHHFEHLDL 294 8**************************98876632222222222222.2223333332.........379***************** PP Methyltransf_12 85 aldniyklLkpgGr 98 +l++i ++L +G tr|I7MI07|I7MI07_TETTS 295 MLREIQRVLLIEGY 308 *********88876 PP == domain 2 score: -0.6 bits; conditional E-value: 8 Methyltransf_12 50 nvnlealdlldldgg...............ssfDvvvasnvlhhl 79 +n e+++++++++ + D v+ +n l+ tr|I7MI07|I7MI07_TETTS 408 SLNEEQEEDSQEKSSsnnfssresinsqgqQEGDDVLYFNQLSLS 452 333333333322222333333333333333555656666655555 PP == domain 3 score: -0.7 bits; conditional E-value: 8.5 Methyltransf_12 35 dakeklakrennnnnnvnlealdlldldgg 64 a++k +++++ + n+ ++ +++ ++++++ tr|I7MI07|I7MI07_TETTS 497 LAQNKQQQQQKTQLNQTHFIQEEKISTQER 526 567777777777777777777766655544 PP >> sp|Q230X8|HENMT_TETTS Small RNA 2'-O-methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=HEN1 P # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.0 0.1 7.3e-07 0.00031 1 95 [. 39 147 .. 39 148 .. 0.72 Alignments for each domain: == domain 1 score: 22.0 bits; conditional E-value: 7.3e-07 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsai.....edakeklakrennnnnnvnlealdlldldgg.................ss 66 L+ G++t l+++l ++l+ +++ g+Di+ + + + + + ++n+ + ++ +l ++ sp|Q230X8|HENMT_TETTS 39 LDMGTNTCKLIQRLSRSLQFTQIDGLDIDGQLLetqgiQ---NAKPDLIQNQYASMRDHQL-------VvnlyqgsalnkiqhlkdQQ 116 89*******************************553332...3333333333333333333.......233333357779999999** PP Methyltransf_12 67 fDvvvasnvlhhl..kdirealdniyklLkp 95 +D+v++ ++++hl +d+ + +n+ L+p sp|Q230X8|HENMT_TETTS 117 YDAVILVELIEHLqvEDVFLIEQNLFGFLRP 147 *************777766666677777766 PP >> tr|I7MDV1|I7MDV1_TETTS UbiE/COQ5 family methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTH # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.3 0.0 2.8e-07 0.00012 1 99 [] 340 435 .. 340 435 .. 0.73 Alignments for each domain: == domain 1 score: 23.3 bits; conditional E-value: 2.8e-07 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDi.spsaiedakeklakrennnnnnvnlealdlldldgg..ssfDvvvasnvlhhlkdire 84 L+ GcG+ ++++ + + ++g+Di s+++ + + + +++ ++ + + + ++l++ +s +++++ vlhh+++++ tr|I7MDV1|I7MDV1_TETTS 340 LDMGCGNCEITAQIGKVYGAKYIVGCDIySEDQF-VRPADTPSNI----QFTYIANKK-DSLQPVqdKSLNLITCFMVLHHIENLDT 420 89***************7777788***8555555.2333333333....233333222.233333458******************* PP Methyltransf_12 85 aldniyklLkpgGrl 99 l+++ +++ +gG l tr|I7MDV1|I7MDV1_TETTS 421 NLKELQRVIIDGGYL 435 ************986 PP >> tr|Q231D4|Q231D4_TETTS mRNA cap guanine-N7 methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN= # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.8 0.0 4e-07 0.00017 1 99 [] 249 374 .. 249 374 .. 0.92 Alignments for each domain: == domain 1 score: 22.8 bits; conditional E-value: 4e-07 Methyltransf_12 1 LeiGcGtGsllralleklpdieyt.gvDispsaiedakeklakrennnnnnvnlealdlldldgg...................... 64 +ei cG G l+++l + di ++ gvDis ++++ a+++++++ ++ ++n+++ + + ++ tr|Q231D4|Q231D4_TETTS 249 MEIACGQGGDLKKWLHA--DIGLYvGVDISFNSLKEASRRTKDIMEKLPPHWNYKKFKYGFYQKDgsastdefwkhihdkdkdqdks 333 69***************..776666*********************9999999999998877666899*****************99 PP Methyltransf_12 65 ..ssfDvvvasnvlhhl....kdirealdniyklLkpgGrl 99 fD+v + ++h++ ++ r +++n+ + L++ G l tr|Q231D4|Q231D4_TETTS 334 krFFFDIVSCQMAMHYMfgseQHARNFFSNATQRLNDQGYL 374 87789***************99999***********99976 PP >> tr|W7XCF3|W7XCF3_TETTS HemK methyltransferase family protein OS=Tetrahymena thermophila (strain SB210) OX=312017 GN= # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.5 0.2 4.5e-06 0.0019 1 73 [. 120 198 .. 120 250 .. 0.80 Alignments for each domain: == domain 1 score: 19.5 bits; conditional E-value: 4.5e-06 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsai....edakeklakrennnnnnvnlealdlldldgg....ssfDvvvas 73 LeiG GtG+++ ll++ ++++tg+ i+++ ++ + l+k+++++ + ++le+l+ +++ + ++fD +v++ tr|W7XCF3|W7XCF3_TETTS 120 LEIGIGTGAISLSLLKE--NSQFTGIAIDKQKFcielAKQNLNLNKIDPQRLQLIHLECLKFFQNNLNqnpdQQFDFIVSN 198 8****************..777777777766666655555555666666666666666555555444466678****9975 PP >> tr|I7M0P5|I7M0P5_TETTS S-adenosylmethionine-dependent methyltransferase OS=Tetrahymena thermophila (strain SB210) OX # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.0 0.0 3.1e-06 0.0013 3 99 .] 88 192 .. 86 192 .. 0.83 Alignments for each domain: == domain 1 score: 20.0 bits; conditional E-value: 3.1e-06 Methyltransf_12 3 iGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhl.......... 79 +GcG+++l ++ ++ +++ +D+s +i++ +ek+ +++ + nl++ ++ g fDvv+ ++ +l tr|I7M0P5|I7M0P5_TETTS 88 VGCGNSQLGPEMTQD-GYENVISSDFSVTVIKNMSEKFPEQKWVVSDVKNLKEFQD----G--EFDVVFDKATMDALvtdegscwnp 167 9*************9.555666*********8888888888854444444444443....3..9************999999**99* PP Methyltransf_12 80 .....kdirealdniyklLkpgGrl 99 +d e+ + ++++Lk++G++ tr|I7M0P5|I7M0P5_TETTS 168 nqktvDDCSEMCQAVHRVLKKEGKF 192 **9999999************9985 PP >> tr|I7M1Y0|I7M1Y0_TETTS Protein-L-isoaspartate O-methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=31201 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.9 0.0 3.3e-06 0.0014 1 78 [. 114 199 .. 114 221 .. 0.73 Alignments for each domain: == domain 1 score: 19.9 bits; conditional E-value: 3.3e-06 Methyltransf_12 1 LeiGcGtGsllrallekl.....pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg......ssfDvvvasnvl 76 L+iGcGtG l a+l+ + ++++++g+D ++ + + + + + + + ++++ +++ l dg+ + +D++++ + tr|I7M1Y0|I7M1Y0_TETTS 114 LDIGCGTGYLCPAFLKMIpvqfqQQSTIVGIDHVKDLV-QLSDRNIR--KSFSQELDKKQIILVTGDGRegyqqlAPYDAIHVGAAA 197 8*********************99**************.33333222..22344555555555555555667779999999877665 PP Methyltransf_12 77 hh 78 + tr|I7M1Y0|I7M1Y0_TETTS 198 EK 199 55 PP >> tr|Q23MB9|Q23MB9_TETTS tRNA (guanine-N(7)-)-methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.6 0.8 3.5 1.5e+03 42 61 .. 3 22 .. 1 37 [. 0.59 2 ! 17.2 0.0 2.2e-05 0.0094 1 46 [. 119 164 .. 119 179 .. 0.88 Alignments for each domain: == domain 1 score: 0.6 bits; conditional E-value: 3.5 Methyltransf_12 42 krennnnnnvnlealdlldl 61 +++nn+nnn+++e++d ++ tr|Q23MB9|Q23MB9_TETTS 3 QESNNKNNNNHIEDEDNEKP 22 44555555555555554333 PP == domain 2 score: 17.2 bits; conditional E-value: 2.2e-05 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrenn 46 L+iGcG G l++ l++++p+ ++g++i + ++ +ek+++ + + tr|Q23MB9|Q23MB9_TETTS 119 LDIGCGFGGLVFNLAKNFPEKLVLGLEIRDKLVNYVSEKIKALRIE 164 8********************************9999998887655 PP >> tr|Q24D56|Q24D56_TETTS UbiE/COQ5 methyltransferase, putative OS=Tetrahymena thermophila (strain SB210) OX=312017 GN= # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.5 0.0 4.3e-06 0.0018 1 41 [. 48 89 .. 48 125 .. 0.74 Alignments for each domain: == domain 1 score: 19.5 bits; conditional E-value: 4.3e-06 Methyltransf_12 1 LeiGcGtGsllrallekl.pdieytgvDispsaiedakekla 41 Le+G+G G l + ++ p+++y+++D+s++++ ++l+ tr|Q24D56|Q24D56_TETTS 48 LEVGAGAGFLYNHTMNYKrPEASYVATDLSEKMLSILCKRLQ 89 8***************9999**************54444443 PP >> tr|W7X1L8|W7X1L8_TETTS AdoMet-dependent proline di-methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=31 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.9 0.0 1.4e-05 0.0058 1 98 [. 111 205 .. 111 206 .. 0.87 Alignments for each domain: == domain 1 score: 17.9 bits; conditional E-value: 1.4e-05 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhl..kdirea 85 L+ G+G G+++++ll++ ++ ++ + i ak++l+++ n ++ + l + + ++++D +++ v + + +d ++ tr|W7X1L8|W7X1L8_TETTS 111 LDCGAGIGRVTKELLMN-VFQKVDLLEQCDKYIFEAKNQLKQYPN----VEDFYQMGLQEFQFQKQYDCIWIQWVSNQIkdDDYVRF 192 899**************.999999***99999999*******996....5555555555555558**************988999** PP Methyltransf_12 86 ldniyklLkpgGr 98 l+++ + L+++G tr|W7X1L8|W7X1L8_TETTS 193 LQKCSNSLSQDGF 205 ***********97 PP >> tr|I7MKV3|I7MKV3_TETTS Arginine N-methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM_00 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.8 0.2 1.4 6e+02 38 76 .. 53 101 .. 44 121 .. 0.63 2 ! 19.3 0.0 5e-06 0.0021 1 97 [. 131 227 .. 131 229 .. 0.73 Alignments for each domain: == domain 1 score: 1.8 bits; conditional E-value: 1.4 Methyltransf_12 38 eklakrennnnnnvnlealdlldldgg..........ssfDvvvasnvl 76 ++++k ++nn+nn+nl+++ + d+ ++ ++D +n tr|I7MKV3|I7MKV3_TETTS 53 KRTSKDIGNNHNNFNLDTCFDNDNIKEeskgyernqdYYYDSYSHFNIH 101 5666677777777777666555444444556887777677765555555 PP == domain 2 score: 19.3 bits; conditional E-value: 5e-06 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.ssfDvvv...asnvlhhlkdir 83 L+iGcGtG l+ +++ +++gvD + +ak+ + ++ +++++l + ++++ + + +++D+++ + +l + ++ tr|I7MKV3|I7MKV3_TETTS 131 LDIGCGTGILSIFAAKA-GAKHVYGVDNANIIL-HAKAIVKNNN--LADKITLIQGKMEEVELPvEKVDIIIsewMGYFLLYESMLD 213 8*******999999999.999999***998888.5555555444..57889999888888777799***999555555555545555 PP Methyltransf_12 84 ealdniyklLkpgG 97 +ld k L+ +G tr|I7MKV3|I7MKV3_TETTS 214 CVLDARDKYLASDG 227 55555556666555 PP >> tr|Q236L4|Q236L4_TETTS L-isoaspartate O-methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTH # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.9 0.1 1.4e-05 0.0057 1 77 [. 152 238 .. 152 252 .. 0.85 Alignments for each domain: == domain 1 score: 17.9 bits; conditional E-value: 1.4e-05 Methyltransf_12 1 LeiGcGtGsllrallekl......pdieyt..gvDispsaiedakeklakrennnnnnvnlealdlldldgg..ssfDvvvasnvlh 77 L+iGcG G +++a+ + + +di++ g+Di ++ a e l+k + n+n +++++l+++++ ++ + +D++++ +l+ tr|Q236L4|Q236L4_TETTS 152 LDIGCGRGYIAFAISKIIekcddlKDIKVFvkGIDIYEDLTYGANEILHKLNINKNITFQFDTLNIEQEIQNkqQVYDIIHSGVALE 238 8*************9999******66655556*********999999******************8877766989999998766555 PP >> tr|Q231Q8|Q231Q8_TETTS SAM-dependent methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.0 0.0 0.00011 0.047 64 98 .. 113 160 .. 56 161 .. 0.62 Alignments for each domain: == domain 1 score: 15.0 bits; conditional E-value: 0.00011 Methyltransf_12 64 g.............ssfDvvvasnvlhhlkdirealdniyklLkpgGr 98 +s D+v+++ +h+++d+ +++i + Lkp+G tr|Q231Q8|Q231Q8_TETTS 113 YplivdeelfpfksESLDMVISNMNMHYVNDLSVGFSRILDSLKPDGT 160 134455556778999*******************************95 PP >> tr|Q22SV4|Q22SV4_TETTS Ribosomal protein L11 methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 G # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.5 0.0 0.00015 0.065 2 51 .. 291 345 .. 290 365 .. 0.75 Alignments for each domain: == domain 1 score: 14.5 bits; conditional E-value: 0.00015 Methyltransf_12 2 eiGcGtGsllralleklpdieytgvDispsai.....edakeklakrennnnnnv 51 ++GcG+G l++ ++e+ p++++t +D ++a+ + a + l++r++n + tr|Q22SV4|Q22SV4_TETTS 291 DLGCGSGILSFIIAEAAPEVKITSLDKYEAAVrctgmNSAILSLSSRIRNEIFDI 345 89*************************9999955544444444444444444444 PP >> tr|W7XFN0|W7XFN0_TETTS Kinase domain protein OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM_000213629 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.0 0.1 0.017 7.3 12 38 .. 71 95 .. 58 121 .. 0.68 2 ? 5.1 0.1 0.13 57 10 60 .. 124 173 .. 119 189 .. 0.72 Alignments for each domain: == domain 1 score: 8.0 bits; conditional E-value: 0.017 Methyltransf_12 12 ralleklpdieytgvDispsaiedake 38 + +l k++++ey+++Dis + i d + tr|W7XFN0|W7XFN0_TETTS 71 STVLLKFQNLEYLFIDISHNEI-DS-Q 95 4455566*************99.33.3 PP == domain 2 score: 5.1 bits; conditional E-value: 0.13 Methyltransf_12 10 llralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlld 60 l+ ++l+ + ++t +Di+ + +ak + ++ ++++++n+n+ ++ +l+ tr|W7XFN0|W7XFN0_TETTS 124 LTCMILQLQKLKQLTILDIDLQHS-QAKDHGNSLQGQSFQNLNNLNTLILK 173 566677776677888888888888.88888888888887777777766543 PP >> tr|Q23EX7|Q23EX7_TETTS Methyltransferase small domain protein OS=Tetrahymena thermophila (strain SB210) OX=312017 GN # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.4 0.1 0.00035 0.15 1 73 [. 62 139 .. 62 167 .. 0.84 Alignments for each domain: == domain 1 score: 13.4 bits; conditional E-value: 0.00035 Methyltransf_12 1 LeiGcGtGsllrallekl.....pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvas 73 +eiG+G+G l+ +l l + + +++Di+ +a +++ ++++ ++++vn ++ + l + +++ Dvv+++ tr|Q23EX7|Q23EX7_TETTS 62 VEIGSGSGILINHLVSFLdkknkSSSLAIAIDINYDANILTQKYANHYHLSQVECVNTDVAEGLYNRLKGQADVVICN 139 69********9999988888874444455******9998899999999999999999999999988888*******97 PP >> tr|Q236M3|Q236M3_TETTS Transmembrane protein, putative OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.6 0.00032 0.14 14 76 .. 1183 1256 .. 1178 1271 .. 0.88 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 0.00032 Methyltransf_12 14 lleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg...........ssfDvvvasnvl 76 + kl+ i+++g+ i ++ie+ ++ +k++++n++++n+e+++++++ + +++D +++ + l tr|Q236M3|Q236M3_TETTS 1183 VGTKLKKIDLLGTNIGIQSIEQIRKNKKKINQENATENNNENNQAIEQNTKekeqeqlkllkQKWDQILSQGYL 1256 566778999*************************************9999999**************9987766 PP >> tr|I7M9J8|I7M9J8_TETTS NOL1/NOP2/Sun family protein OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM_00 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 0.0 0.00036 0.15 4 72 .. 219 288 .. 216 290 .. 0.88 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 0.00036 Methyltransf_12 4 GcGtGsllrallekl.pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvva 72 +G G + a++++l + +++ D ++ ak++++k + +n+++ + e l+ +++ ++fD vv+ tr|I7M9J8|I7M9J8_TETTS 219 CAGAGGKSLAFAPYLkGTGQIYLHDTRDYILQEAKKRFNKAGIQNVQFHTQESLNNNKNKLVKKFDWVVC 288 5777888888888886699999******************************9998888888******98 PP >> tr|Q23GA7|Q23GA7_TETTS Bicoid-interacting protein OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM_0007 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.6 0.1 0.00031 0.13 1 41 [. 143 183 .. 143 215 .. 0.72 2 ? 5.1 9.6 0.14 58 42 99 .] 437 499 .. 282 499 .. 0.85 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 0.00031 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakekla 41 L+iGc++Gsl+ ++ k + +++g+Di+ + i++a + tr|Q23GA7|Q23GA7_TETTS 143 LDIGCNDGSLTLLIAIKYFPFKIVGIDIDFNLINKAVGNYN 183 8*******************************955544333 PP == domain 2 score: 5.1 bits; conditional E-value: 0.14 Methyltransf_12 42 krennnnnnvnlealdlldldgg.....ssfDvvvasnvlhhl......kdirealdniyklLkpgGrl 99 kr+ +n++++le+ + ++fD++ ++++ ++ + i++++d++y+ L+ +G++ tr|Q23GA7|Q23GA7_TETTS 437 KRRFPQNTKFRLENYV------EsteltEKFDTICCFSTTKWIhlnfgdQGIKRLFDKVYRSLRVNGIF 499 2333334444444444......0344457*******************99*****************75 PP >> tr|I7M290|I7M290_TETTS Uncharacterized protein OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM_0013814 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.8 0.2 0.00026 0.11 18 83 .. 11 75 .. 4 87 .. 0.83 Alignments for each domain: == domain 1 score: 13.8 bits; conditional E-value: 0.00026 Methyltransf_12 18 l..pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhlkdir 83 + ++ +y++++ s+ + ekl++ ++ + n+++ ++ +l d++ + D+++++++++++k ++ tr|I7M290|I7M290_TETTS 11 NdkENFKYCCSEMSQILE-THTEKLKSLRQTFYNCIQQQCKKLQDSQL--QNDIILINELISVIKSRK 75 334789999999998776.9**********************999888..9************95433 PP >> tr|Q24FF7|Q24FF7_TETTS Methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM_00865060 PE=4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.3 0.0 0.00076 0.32 1 90 [. 70 162 .. 70 165 .. 0.60 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 0.00076 Methyltransf_12 1 LeiGcGtGsllralleklpdieyt.gvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhl...kdir 83 Le+G+G+G +++++ +++ +t g Di + + ++ a+++n +++ + +l+ l++ + +fD+++ ++ + + + ++ tr|Q24FF7|Q24FF7_TETTS 70 LEVGAGVGLSGLVCAQYAKQVYITdGNDIVCELM-EMNAQYAQNNNVVMEKYCWGDLSYLEKRKDIKFDIIIGADIMFWEssiEPLA 155 8****************55555555555555555.55555555555555555555555555544499**999665543322235555 PP Methyltransf_12 84 ealdniy 90 +l+++y tr|Q24FF7|Q24FF7_TETTS 156 ITLKQAY 162 5555555 PP >> tr|Q23AQ0|Q23AQ0_TETTS Tetratricopeptide repeat protein OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHER # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.5 0.0 7.7 3.2e+03 26 74 .. 321 371 .. 315 374 .. 0.67 2 ? 9.3 0.1 0.0065 2.8 46 94 .. 476 525 .. 459 527 .. 0.73 Alignments for each domain: == domain 1 score: -0.5 bits; conditional E-value: 7.7 Methyltransf_12 26 vDispsai.edakeklakrennnnnnvnlealdlldldgg.....ssfDvvvasn 74 +D+ ++++ +da+ + a++++n ++ l l+ + fD+++a++ tr|Q23AQ0|Q23AQ0_TETTS 321 SDLEEQSLyKDASGRYAFNKANPYMSHENP----LHLALEfiasgRPFDAILALE 371 788889988888888888887554443333....223333345678999998875 PP == domain 2 score: 9.3 bits; conditional E-value: 0.0065 Methyltransf_12 46 nnnnnvnlealdlldldggssfDvvvasnvlhhl.kdirealdniyklLk 94 +n n++ l+a ++ ++ ++ D+ v++ vl+++ +d + ++++++++Lk tr|Q23AQ0|Q23AQ0_TETTS 476 KNMNKNMLDAFYAARNQFPQNADLHVCLAVLQYIsRDYQGSVESFREALK 525 333344444444334444489***************************98 PP >> tr|W7X6G9|W7X6G9_TETTS Uncharacterized protein OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM_0007036 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 2.1 0.1 1.1 4.7e+02 19 59 .. 42 80 .. 25 87 .. 0.71 2 ? 7.1 0.1 0.032 14 22 64 .. 90 132 .. 81 154 .. 0.83 3 ? 1.9 0.1 1.3 5.5e+02 19 68 .. 190 240 .. 180 266 .. 0.73 Alignments for each domain: == domain 1 score: 2.1 bits; conditional E-value: 1.1 Methyltransf_12 19 pdieytgvDispsaiedakeklakrennnnnnvnlealdll 59 +i++t++D+++++++ ++ +a ++ ++++l a+++ tr|W7X6G9|W7X6G9_TETTS 42 TGIHFTVLDLNSKSLDSLQAIFANYK--ALTKIDLHANNIQ 80 6899***********55555555444..5667777777765 PP == domain 2 score: 7.1 bits; conditional E-value: 0.032 Methyltransf_12 22 eytgvDispsaiedakeklakrennnnnnvnlealdlldldgg 64 +++++D+s++ i+d k ++++ +n + +n+ ++ +++l + tr|W7X6G9|W7X6G9_TETTS 90 NLIWLDVSQNNIKDLKSLQNEEGFRNLKYLNISKNRISELLTP 132 578****************************999999988766 PP == domain 3 score: 1.9 bits; conditional E-value: 1.3 Methyltransf_12 19 pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg..ssfD 68 + +++g+D s + ++l+ +e+ n+ nle+l+ l+l ++ ++f tr|W7X6G9|W7X6G9_TETTS 190 KIKTVVGIDSLVSLT-KLHLRLNNIEQFEENFPNLENLQYLNLRENkiDKFE 240 466788999877777.888999999999999999999998888776554554 PP >> tr|I7MMN8|I7MMN8_TETTS UPF0586 C9orf41-like protein, putative OS=Tetrahymena thermophila (strain SB210) OX=312017 GN # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.7 0.2 8.4 3.6e+03 46 73 .. 101 138 .. 45 155 .. 0.55 2 ? 12.6 0.0 0.00063 0.27 64 98 .. 360 409 .. 276 410 .. 0.73 Alignments for each domain: == domain 1 score: -0.7 bits; conditional E-value: 8.4 Methyltransf_12 46 nnnnnvnlealdlldldgg..........ssfDvvvas 73 n+ n+ ++++ ++ +++ ++f vv+s tr|I7MMN8|I7MMN8_TETTS 101 NSMNFPEFQEPTDAYRPEHnqflqdeeefKHFRQVVCS 138 33344444433333333334444444445555555555 PP == domain 2 score: 12.6 bits; conditional E-value: 0.00063 Methyltransf_12 64 g...............ssfDvvvasnvlhhlkdirealdniyklLkpgGr 98 + + v ++++ +di e+++ i+k+LkpgG+ tr|I7MMN8|I7MMN8_TETTS 360 FsmaagefveiykkqpEEWHGVCTIFFIDTANDIVEYIKTIHKCLKPGGV 409 1444446777777777899999999************************6 PP >> tr|Q235Z8|Q235Z8_TETTS Kinase domain protein, putative OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.7 0.1 3.2 1.4e+03 13 61 .. 379 427 .. 373 471 .. 0.66 2 ? 2.4 0.0 0.96 4e+02 11 36 .. 677 703 .. 644 721 .. 0.83 3 ? 4.4 0.0 0.22 95 3 33 .. 729 759 .. 728 811 .. 0.73 Alignments for each domain: == domain 1 score: 0.7 bits; conditional E-value: 3.2 Methyltransf_12 13 alleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldl 61 +l++++ ++ + +D+s + i d+++ + + ++ +++ +ldl+++ tr|Q235Z8|Q235Z8_TETTS 379 TILKNFKKLQNLHLDLSNNKICDKALSYIASGLSECESIKILNLDLSSN 427 5666667777777778877777777777777777777777777766554 PP == domain 2 score: 2.4 bits; conditional E-value: 0.96 Methyltransf_12 11 lralleklpdieytgvDispsai.eda 36 l+ l+k+++i+y+ + +s+++i +d tr|Q235Z8|Q235Z8_TETTS 677 LSTALAKNQNISYLLINFSQNQItQDG 703 566778889***********9995444 PP == domain 3 score: 4.4 bits; conditional E-value: 0.22 Methyltransf_12 3 iGcGtGsllralleklpdieytgvDispsai 33 +Gc + ++ lekl++i+ +++D+s++++ tr|Q235Z8|Q235Z8_TETTS 729 LGCQGSVSISQALEKLQNISKLYLDLSENQV 759 79***************************99 PP >> tr|Q23YT4|Q23YT4_TETTS EF-1 guanine nucleotide exchange domain protein OS=Tetrahymena thermophila (strain SB210) OX= # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.4 0.0 4 1.7e+03 37 64 .. 101 128 .. 95 154 .. 0.75 2 ? 9.9 0.3 0.0044 1.8 19 94 .. 179 279 .. 158 284 .. 0.76 Alignments for each domain: == domain 1 score: 0.4 bits; conditional E-value: 4 Methyltransf_12 37 keklakrennnnnnvnlealdlldldgg 64 k+k +k++ n+++++++ a+dl l++ tr|Q23YT4|Q23YT4_TETTS 101 KLKNKKQKTNQFSKMTFSATDLPTLEKH 128 6788899999999999999998877765 PP == domain 2 score: 9.9 bits; conditional E-value: 0.0044 Methyltransf_12 19 pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg..........................ssfDvvvasnvlhhl 79 p+++ t+ D+ p a++ a++k ak+e +++ v+l+ d++++++ ++ +v+ v+++ tr|Q23YT4|Q23YT4_TETTS 179 PEAQNTWADVAPVAVPVAAKKEAKKET-KTDDVDLFGDDDEEDAEAealrekkrleavaakeardgkkkkaiAKTILVFNVKVFEAE 264 68899**********999999999885.77889988888777666678888888888888877777777766555566666777777 PP Methyltransf_12 80 kdirealdniyklLk 94 +d++++ ++iy+ + tr|Q23YT4|Q23YT4_TETTS 265 QDLDALAKKIYETIQ 279 777777777777665 PP >> tr|Q22Z09|Q22Z09_TETTS 16S rRNA methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM_0011 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.9 0.2 9.7 4.1e+03 31 58 .. 64 91 .. 52 114 .. 0.53 2 ? 10.1 0.0 0.0038 1.6 7 58 .. 135 185 .. 130 214 .. 0.68 3 ? 0.9 0.0 2.8 1.2e+03 19 96 .. 265 352 .. 251 353 .. 0.56 Alignments for each domain: == domain 1 score: -0.9 bits; conditional E-value: 9.7 Methyltransf_12 31 saiedakeklakrennnnnnvnlealdl 58 ++i++ + + ++++ + + ++ ++ l tr|Q22Z09|Q22Z09_TETTS 64 QMIQQQQSQKKQNSSLDEEAIQHNDDIL 91 5664444444444433333333333332 PP == domain 2 score: 10.1 bits; conditional E-value: 0.0038 Methyltransf_12 7 tGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdl 58 ++ ++++l+k+p + ++g+D++p+++ + + k + + +++++++++ tr|Q22Z09|Q22Z09_TETTS 135 SAGHAKHFLQKFPYLYILGLDLDPRML-QYINDNVKSQLSHSDQNRFKTRNE 185 555678999******************.333333333334444444444442 PP == domain 3 score: 0.9 bits; conditional E-value: 2.8 Methyltransf_12 19 pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.....ssfDvvvas.nvlhhl.....kdirealdniy.klL 93 + i+ +g D+++++i + +++r+ + ++ + + +l++++g +++ +++ + ++l +++ ++d+iy klL tr|Q22Z09|Q22Z09_TETTS 265 EIIRQYGEDPNADVISQ--MIIKQRQIKPFETTKDVVDLILEDQSGysfkgGQYKAITKLfQALRIAtnqelTNLQVFMDKIYdKLL 349 56667777777777722..22233332233333333333333333346667777777744255555577777888888888886677 PP Methyltransf_12 94 kpg 96 k+g tr|Q22Z09|Q22Z09_TETTS 350 KDG 352 665 PP >> tr|I7MLP7|I7MLP7_TETTS Heat shock-binding protein 70, ER luminal protein OS=Tetrahymena thermophila (strain SB210) O # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.3 0.1 0.0032 1.3 13 89 .. 414 490 .. 402 492 .. 0.82 Alignments for each domain: == domain 1 score: 10.3 bits; conditional E-value: 0.0032 Methyltransf_12 13 alleklpdieyt.gvDispsaiedakeklakrennnnnnvnlealdlldldggssfDv..vvasnvlhhlkdirealdni 89 l +++ +++ g+D+s++ +ek+ +++ + +++v++ +d+l++ g ++ D+ +++++ ++++ir++++++ tr|I7MLP7|I7MLP7_TETTS 414 LLKTQIKIQNLVdGLDFSEELT---REKFEEINTDLFQKVTNTIQDVLNKSGLNKIDIdnIILIGGSTYIPKIRKSIQEF 490 4445554444445*******99...**********************9999996666666**************999875 PP >> tr|Q231G1|Q231G1_TETTS U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase OS=Tetrahymena thermophila (strain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.2 0.0 0.015 6.1 2 54 .. 167 218 .. 166 233 .. 0.79 Alignments for each domain: == domain 1 score: 8.2 bits; conditional E-value: 0.015 Methyltransf_12 2 eiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnle 54 +iG+G + + l ++ +++++++++s ++ + ++k+ ++++ n+v+l+ tr|Q231G1|Q231G1_TETTS 167 DIGTGASVIYPILGASKYNWSFIATELSDASY-QNAKKIINNNPQLKNKVELR 218 9*********99*99999**************.55555555555555555554 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (99 nodes) Target sequences: 26971 (16912921 residues searched) Passed MSV filter: 4079 (0.151237); expected 539.4 (0.02) Passed bias filter: 3012 (0.111676); expected 539.4 (0.02) Passed Vit filter: 353 (0.0130881); expected 27.0 (0.001) Passed Fwd filter: 133 (0.00493122); expected 0.3 (1e-05) Initial search space (Z): 26971 [actual number of targets] Domain search space (domZ): 64 [number of targets reported over threshold] # CPU time: 0.98u 0.02s 00:00:01.00 Elapsed: 00:00:00.27 # Mc/sec: 6201.40 // [ok]