# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/Methyltransf_12.hmm.txt # target sequence database: proteomes/Thermococcus_kodakarensis.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: Methyltransf_12 [M=99] Accession: PF08242.11 Description: Methyltransferase domain Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.2e-15 53.8 0.0 5.1e-15 53.1 0.0 1.3 1 tr|Q5JHQ2|Q5JHQ2_THEKO SAM-dependent methyltransferase, UbiE 5.9e-15 52.9 0.0 8.5e-15 52.4 0.0 1.2 1 tr|Q5JG68|Q5JG68_THEKO SAM-dependent methyltransferase, UbiE 2.6e-14 50.9 0.0 4.6e-14 50.1 0.0 1.4 1 tr|Q5JGN8|Q5JGN8_THEKO SAM-dependent methyltransferase, UbiE 2.2e-12 44.7 0.0 3.1e-12 44.2 0.0 1.2 1 tr|Q5JFS6|Q5JFS6_THEKO Predicted SAM-dependent methyltransfe 2.7e-12 44.4 0.0 3.2e-11 40.9 0.0 2.2 2 tr|Q5JED8|Q5JED8_THEKO SAM-dependent methyltransferase, UbiE 1.3e-11 42.2 0.0 2.5e-11 41.3 0.0 1.5 1 tr|Q5JFQ4|Q5JFQ4_THEKO SAM-dependent methyltransferase, UbiE 4.6e-10 37.2 0.0 8e-10 36.5 0.0 1.4 1 tr|Q5JG60|Q5JG60_THEKO SAM-dependent methyltransferase, UbiE 5.7e-06 24.1 0.0 9.2e-06 23.5 0.0 1.3 1 tr|Q5JJF0|Q5JJF0_THEKO Ribosomal RNA small subunit methyltra 0.00012 19.9 0.0 0.00038 18.3 0.0 1.9 1 tr|Q5JIX8|Q5JIX8_THEKO N5-glutamine methyltransferase, HemK 0.00026 18.8 0.0 0.001 16.9 0.0 1.9 1 tr|Q5JID5|Q5JID5_THEKO N2, N2-dimethylguanosine tRNA methylt 0.00057 17.7 0.0 0.0017 16.1 0.0 1.7 2 tr|Q5JJ79|Q5JJ79_THEKO Predicted SAM-dependent methyltransfe 0.00069 17.4 0.0 0.0019 16.0 0.0 1.7 1 tr|Q5JGS7|Q5JGS7_THEKO tRNA (1-methyladenosine) methyltransf 0.0011 16.8 0.0 0.017 13.0 0.0 2.3 2 tr|Q5JF97|Q5JF97_THEKO Chemotaxis protein methyltransferase 0.0021 15.9 0.1 0.021 12.7 0.0 2.6 2 tr|Q5JDB4|Q5JDB4_THEKO tRNA/rRNA cytosine-C5-methylase, NOL1 0.0063 14.3 0.0 0.022 12.6 0.0 1.9 2 tr|Q5JH73|Q5JH73_THEKO Uncharacterized protein OS=Thermococc ------ inclusion threshold ------ 0.012 13.5 0.0 2.4 6.1 0.0 2.5 2 tr|Q5JDP5|Q5JDP5_THEKO tRNA/rRNA cytosine-C5-methylase, NOL1 0.019 12.8 0.0 0.03 12.2 0.0 1.3 1 tr|Q5JDP7|Q5JDP7_THEKO Predicted DNA methylase OS=Thermococc Domain annotation for each sequence (and alignments): >> tr|Q5JHQ2|Q5JHQ2_THEKO SAM-dependent methyltransferase, UbiE/COQ5 family OS=Thermococcus kodakarensis (strain ATCC B # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 53.1 0.0 3.8e-17 5.1e-15 1 99 [] 43 138 .. 43 138 .. 0.89 Alignments for each domain: == domain 1 score: 53.1 bits; conditional E-value: 3.8e-17 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhl..kdirea 85 L++ cG+G +++ l++ + e++g+D s+ ++ +++++ak+++ ++++++ +a++l + +sfD+v+ ++ l h+ +d++++ tr|Q5JHQ2|Q5JHQ2_THEKO 43 LDLACGVGGFSFLLEDL--GFEVVGLDNSRFML-EKAREFAKEKESRVEFIEGDARELPFEN--DSFDYVLFIDSLVHFepQDLAKV 124 89***************..**************.6666777777778888888888876544..6********************** PP Methyltransf_12 86 ldniyklLkpgGrl 99 +++ +++LkpgG++ tr|Q5JHQ2|Q5JHQ2_THEKO 125 FKETARVLKPGGKF 138 ************86 PP >> tr|Q5JG68|Q5JG68_THEKO SAM-dependent methyltransferase, UbiE/COQ5 family OS=Thermococcus kodakarensis (strain ATCC B # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 52.4 0.0 6.3e-17 8.5e-15 1 98 [. 40 131 .. 40 132 .. 0.86 Alignments for each domain: == domain 1 score: 52.4 bits; conditional E-value: 6.3e-17 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.ssfDvvvasnvlhhlkdireal 86 LeiG GtG +lr+ ++ +e++++D s++++e ak++ ++ + v++++ ++++l+ + + fD+vv+s+v++ ++++++a+ tr|Q5JG68|Q5JG68_THEKO 40 LEIGVGTGKTLRYYPQD---VELYAIDGSEKMLEMAKKRAKELGM----DVKFKVAEAESLPFPdDFFDTVVSSFVFCTVPEPERAI 119 8*************666...*************999999999996....455555554444444568******************** PP Methyltransf_12 87 dniyklLkpgGr 98 ++i+++Lkp+G+ tr|Q5JG68|Q5JG68_THEKO 120 EEIKRVLKPDGM 131 ***********7 PP >> tr|Q5JGN8|Q5JGN8_THEKO SAM-dependent methyltransferase, UbiE/COQ5 family OS=Thermococcus kodakarensis (strain ATCC B # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 50.1 0.0 3.4e-16 4.6e-14 1 99 [] 46 141 .. 46 141 .. 0.92 Alignments for each domain: == domain 1 score: 50.1 bits; conditional E-value: 3.4e-16 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvas.nvlhhl..kdire 84 L++ cGtG + +l+e+ + e++g+D++++++ + +++ a+ ++ n+++++ +ald++ ++ fD+v+++ + + ++ ire tr|Q5JGN8|Q5JGN8_THEKO 46 LDLACGTGIPTLELAER--GYEVLGLDLHEEML-RVARRKAEARGLNVKFIRGNALDISFEE---EFDAVTMFfSSIMYFddSAIRE 126 89***************..**************.7777777888899999999999988664...8*******9999999998999* PP Methyltransf_12 85 aldniyklLkpgGrl 99 +++++++ L+pgG++ tr|Q5JGN8|Q5JGN8_THEKO 127 LFNSVRRTLRPGGVF 141 *************86 PP >> tr|Q5JFS6|Q5JFS6_THEKO Predicted SAM-dependent methyltransferase OS=Thermococcus kodakarensis (strain ATCC BAA-918 / # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 44.2 0.0 2.3e-14 3.1e-12 1 99 [] 62 155 .. 62 155 .. 0.87 Alignments for each domain: == domain 1 score: 44.2 bits; conditional E-value: 2.3e-14 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhlkdireald 87 L++GcGtG l+++++ k+ ++gvD +++i ++l +r +n+++v+ + l+++ ld ++fD vv s vlh + +++ +l+ tr|Q5JFS6|Q5JFS6_THEKO 62 LDVGCGTGVLTFKMALKNGVEMVVGVDRKEEVI-EFCNRLGDRVTKNAKFVQGNFLEMG-LD--EKFDSVVFSYVLHDF-EPEPFLE 143 8****************6666667*********.8888888888888777777777754.44..49************7.9****** PP Methyltransf_12 88 niyklLkpgGrl 99 ++ ++L gGr+ tr|Q5JFS6|Q5JFS6_THEKO 144 RALEVLEEGGRV 155 **********85 PP >> tr|Q5JED8|Q5JED8_THEKO SAM-dependent methyltransferase, UbiE/COQ5 family OS=Thermococcus kodakarensis (strain ATCC B # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.1 0.0 0.64 87 59 92 .. 78 111 .. 52 113 .. 0.76 2 ! 40.9 0.0 2.4e-13 3.2e-11 1 99 [] 164 258 .. 164 258 .. 0.87 Alignments for each domain: == domain 1 score: 1.1 bits; conditional E-value: 0.64 Methyltransf_12 59 ldldggssfDvvvasnvlhhl.kdirealdniykl 92 ++l++ s +vva++ +l d++++l++iyk+ tr|Q5JED8|Q5JED8_THEKO 78 IELAEF-SHNLVVAAERYGALvSDWASVLEEIYKM 111 334444.7778888887777789**********98 PP == domain 2 score: 40.9 bits; conditional E-value: 2.4e-13 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhlkdireald 87 L+iGcG+ s + + + y+g+D+s + ++ a++++a + v l+++d+ + +s+Dvv++s+vl++++++++a++ tr|Q5JED8|Q5JED8_THEKO 164 LDIGCGSVSPSYFGRLVGYNGFYLGLDYSYALLDIARARIAGEAL----PVVLKEIDATIIRPVNSYDVVIMSFVLEYIQNRKRAIK 246 89***9665555444444899************999999999986....8888888888777889********************** PP Methyltransf_12 88 niyklLkpgGrl 99 n+ + L+ gG+l tr|Q5JED8|Q5JED8_THEKO 247 NALEGLREGGKL 258 **********97 PP >> tr|Q5JFQ4|Q5JFQ4_THEKO SAM-dependent methyltransferase, UbiE/COQ5 family OS=Thermococcus kodakarensis (strain ATCC B # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 41.3 0.0 1.8e-13 2.5e-11 1 99 [] 44 132 .. 44 132 .. 0.80 Alignments for each domain: == domain 1 score: 41.3 bits; conditional E-value: 1.8e-13 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhl..kdirea 85 +++GcGtG++lr l+ + +y+gv++s+ + ++ +ek + + ++ l++ + +s D+vv+ ++hh+ +++ ea tr|Q5JFQ4|Q5JFQ4_THEKO 44 VDVGCGTGNILRFLRCE----RYIGVEPSEGMRKAFREKWGF------EPIDGHFLEIPLPE--GSADTVVSTYAFHHVpdEEKGEA 118 69************999....************444444433......34455555544322..3**************888888** PP Methyltransf_12 86 ldniyklLkpgGrl 99 ++++ ++L+pgG+l tr|Q5JFQ4|Q5JFQ4_THEKO 119 IREMLRVLRPGGIL 132 ************87 PP >> tr|Q5JG60|Q5JG60_THEKO SAM-dependent methyltransferase, UbiE/COQ5 family OS=Thermococcus kodakarensis (strain ATCC B # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 36.5 0.0 5.9e-12 8e-10 2 99 .] 44 126 .. 43 126 .. 0.87 Alignments for each domain: == domain 1 score: 36.5 bits; conditional E-value: 5.9e-12 Methyltransf_12 2 eiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhlkdirealdn 88 eiG GtG+++++l k +gv++s+++ e a+++ + ++ ++n+ +e+ +s D+ ++ +++ ++d+++al++ tr|Q5JG60|Q5JG60_THEKO 44 EIGVGTGRFAAPLGIK------LGVEPSKAMAEIARTRGIEVIEGTAENLPFEE---------DSMDYLLMVTTICFVDDPEKALKE 115 9***************......**********8888888887765555555542.........289********************* PP Methyltransf_12 89 iyklLkpgGrl 99 +y++LkpgG l tr|Q5JG60|Q5JG60_THEKO 116 AYRVLKPGGAL 126 *********75 PP >> tr|Q5JJF0|Q5JJF0_THEKO Ribosomal RNA small subunit methyltransferase C OS=Thermococcus kodakarensis (strain ATCC BAA # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.5 0.0 6.8e-08 9.2e-06 1 99 [] 61 155 .. 61 155 .. 0.83 Alignments for each domain: == domain 1 score: 23.5 bits; conditional E-value: 6.8e-08 Methyltransf_12 1 LeiGcGtGsllralleklpdieyt.gvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhl.kdirea 85 L++GcG G + + + ++y+ +D++++a+ ++k k+++ +n++v++ l g++fD ++ + +h+ + +re+ tr|Q5JJF0|Q5JJF0_THEKO 61 LDLGCGYGPIGIVASRF---VDYVvMTDVNRRAV-SIAKKNLKINGVRNAEVRWGSLYEP--VAGEKFDSIITNPPVHAGkEVLREI 141 8*******998888666...78777*********.6666666667788899999877744..4446********99999878889** PP Methyltransf_12 86 ldniyklLkpgGrl 99 + n+ ++L++gG l tr|Q5JJF0|Q5JJF0_THEKO 142 VINAPRHLNDGGYL 155 ************86 PP >> tr|Q5JIX8|Q5JIX8_THEKO N5-glutamine methyltransferase, HemK family OS=Thermococcus kodakarensis (strain ATCC BAA-918 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.3 0.0 2.8e-06 0.00038 1 72 [. 39 104 .. 39 148 .. 0.77 Alignments for each domain: == domain 1 score: 18.3 bits; conditional E-value: 2.8e-06 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvva 72 L+ G+GtG ++ l++k ++gvDi+p a+e a+e a+++ nv+++ dl+++ +g fDv++ tr|Q5JIX8|Q5JIX8_THEKO 39 LDMGTGTGIIALLLARK--ARWVLGVDINPLAVELAREN-ARIN--GIINVEFRLSDLFENVSG-EFDVITF 104 89******999999999..77777*********444443.3333..245677777777766666.9999885 PP >> tr|Q5JID5|Q5JID5_THEKO N2, N2-dimethylguanosine tRNA methyltransferase OS=Thermococcus kodakarensis (strain ATCC BAA # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.9 0.0 7.5e-06 0.001 11 99 .] 194 289 .. 188 289 .. 0.81 Alignments for each domain: == domain 1 score: 16.9 bits; conditional E-value: 7.5e-06 Methyltransf_12 11 lralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvv......asnvlhhl......kdirea 85 l + +++++gvDi p+++e a++ l++++ ++ + +a+ l+dl + ++f +v l + r+a tr|Q5JID5|Q5JID5_THEKO 194 LIEAGLL--GLRVYGVDIRPEMVEGAETNLKHYGVRDYTLKLGDATRLEDLFPDKKFEAVAtdppygT---AATLagrkrdELYRKA 275 4444444..89**************************999999999999999999**99996664433...33335558877788** PP Methyltransf_12 86 ldniyklLkpgGrl 99 l++iy++L +gGrl tr|Q5JID5|Q5JID5_THEKO 276 LRSIYNVLEDGGRL 289 ************97 PP >> tr|Q5JJ79|Q5JJ79_THEKO Predicted SAM-dependent methyltransferase, DUF890 family OS=Thermococcus kodakarensis (strain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.1 0.0 1.3e-05 0.0017 1 71 [. 86 156 .. 86 159 .. 0.73 2 ? -1.9 0.0 5.5 7.4e+02 85 98 .. 189 202 .. 186 203 .. 0.82 Alignments for each domain: == domain 1 score: 16.1 bits; conditional E-value: 1.3e-05 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvv 71 LeiG+G ++++ ++e+l ++++t++++++++ e ak+ + k+++n + + + ++g+ fDv++ tr|Q5JJ79|Q5JJ79_THEKO 86 LEIGTGHTAMMALMAERLFNCDVTATELDEEFFEYAKRNIEKNGANVKPIKSNGGIIRGVVPKGERFDVIF 156 899999999999999999***************88888888877644433333333333333338888886 PP == domain 2 score: -1.9 bits; conditional E-value: 5.5 Methyltransf_12 85 aldniyklLkpgGr 98 +++++ + L+pgG+ tr|Q5JJ79|Q5JJ79_THEKO 189 LIEEALEYLNPGGK 202 67888999****98 PP >> tr|Q5JGS7|Q5JGS7_THEKO tRNA (1-methyladenosine) methyltransferase OS=Thermococcus kodakarensis (strain ATCC BAA-918 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.0 0.0 1.4e-05 0.0019 2 98 .. 99 189 .. 98 190 .. 0.80 Alignments for each domain: == domain 1 score: 16.0 bits; conditional E-value: 1.4e-05 Methyltransf_12 2 eiGcGtGsllrallekl.pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhlkdireald 87 e G+G+G+l+ l+++ p+ +++ +++ +++ e ak+ + ++v l++ ++ d ++ D +v+ l++++ +l tr|Q5JGS7|Q5JGS7_THEKO 99 EAGAGSGALTIFLANAVgPTGKVISYEVRKDFYEIAKKNVELAGF--SDRVVLKNKSIYDGIDEKEADHIVL-----DLPQPENVLP 178 89***************99**************888888877775..4566666666544444446666654.....349******* PP Methyltransf_12 88 niyklLkpgGr 98 ++ ++L+pgG tr|Q5JGS7|Q5JGS7_THEKO 179 HAVDVLRPGGY 189 *********97 PP >> tr|Q5JF97|Q5JF97_THEKO Chemotaxis protein methyltransferase OS=Thermococcus kodakarensis (strain ATCC BAA-918 / JCM # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.0 0.0 0.66 90 18 35 .. 134 153 .. 112 167 .. 0.75 2 ! 13.0 0.0 0.00013 0.017 50 99 .] 193 244 .. 182 244 .. 0.80 Alignments for each domain: == domain 1 score: 1.0 bits; conditional E-value: 0.66 Methyltransf_12 18 l..pdieytgvDispsaied 35 l +++++++Di+++a++ tr|Q5JF97|Q5JF97_THEKO 134 LkrYRLKILATDIDREALNT 153 14458999*******99943 PP == domain 2 score: 13.0 bits; conditional E-value: 0.00013 Methyltransf_12 50 nvnlealdlldldggssfDvvvasnvlhhl..kdirealdniyklLkpgGrl 99 v++++ +ll++ + fD++++ nvl ++ + +e+++++y+ L + G l tr|Q5JF97|Q5JF97_THEKO 193 YVEFRHFNLLSDRYPTGFDMIFIRNVLIYMtkEAQEEVFKKLYNSLEDHGYL 244 5667777777666668***************66666**********999976 PP >> tr|Q5JDB4|Q5JDB4_THEKO tRNA/rRNA cytosine-C5-methylase, NOL1/NOP2/Sun family, fused to N-terminal NusB regulator dom # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.7 0.0 9.4 1.3e+03 23 49 .. 127 153 .. 108 160 .. 0.58 2 ! 12.7 0.0 0.00015 0.021 1 72 [. 266 335 .. 266 384 .. 0.68 Alignments for each domain: == domain 1 score: -2.7 bits; conditional E-value: 9.4 Methyltransf_12 23 ytgvDispsaiedakeklakrennnnn 49 + +i + +e+a ++l+++++ + tr|Q5JDB4|Q5JDB4_THEKO 127 ALMHEIEKFDVERALKRLKEKDRIEWL 153 444455555566677777766665555 PP == domain 2 score: 12.7 bits; conditional E-value: 0.00015 Methyltransf_12 1 LeiGcGtGsllrallekl.pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvva 72 L++ + Gs +++ ++ e+++vD+s + + + kek + + +n+ +v+ + ++ d+ ++fD +++ tr|Q5JDB4|Q5JDB4_THEKO 266 LDLAAAPGSKTFHAAALMeNKGEIVAVDYSYDRLMRMKEKAKVLGVKNVRFVHADGQSFRDK---EKFDKIIL 335 7888888998999888886799************9999999999987777777777775544...47777763 PP >> tr|Q5JH73|Q5JH73_THEKO Uncharacterized protein OS=Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.6 0.0 0.00016 0.022 2 59 .. 89 144 .. 88 157 .. 0.82 2 ? -2.0 0.0 5.7 7.8e+02 65 94 .. 269 300 .. 238 302 .. 0.66 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 0.00016 Methyltransf_12 2 eiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdll 59 ++ cG G l ++k + +g+Di+p ie a++ k++ n +++n + l+ + tr|Q5JH73|Q5JH73_THEKO 89 DVSCGIGIQLIFYAMK--VERAYGIDIDPLKIEFARRNAEKYGVSNIEFINADSLSPE 144 899**********999..9999**************9999999877777777666544 PP == domain 2 score: -2.0 bits; conditional E-value: 5.7 Methyltransf_12 65 ssfDvv.vasnvlhhl.kdirealdniyklLk 94 +s D++ ++++++h l + r +l++ +++L+ tr|Q5JH73|Q5JH73_THEKO 269 QSIDYAdLINELFHRLpVEARMLLREKRRVLA 300 56666623558888886666677777777776 PP >> tr|Q5JDP5|Q5JDP5_THEKO tRNA/rRNA cytosine-C5-methylase, NOL1/NOP2/Sun family OS=Thermococcus kodakarensis (strain AT # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.1 0.0 0.018 2.4 8 69 .. 262 324 .. 255 333 .. 0.79 2 ? 4.7 0.0 0.047 6.4 82 99 .] 359 376 .. 351 376 .. 0.86 Alignments for each domain: == domain 1 score: 6.1 bits; conditional E-value: 0.018 Methyltransf_12 8 Gsllrallekl.pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDv 69 G +++++e + ++++ D++++ i++ ke l++ + + ++ ++ + +++ +l g++ D tr|Q5JDP5|Q5JDP5_THEKO 262 GGKTAHMAELMeNRGKIYAFDVDSARIKRMKEVLKRTGVEIAEVIKADGRNAPELLGEEIADR 324 44444444444357***********************99999999999999999888766665 PP == domain 2 score: 4.7 bits; conditional E-value: 0.047 Methyltransf_12 82 irealdniyklLkpgGrl 99 +e+++++ klLkpgGrl tr|Q5JDP5|Q5JDP5_THEKO 359 QKELMESAWKLLKPGGRL 376 568999**********97 PP >> tr|Q5JDP7|Q5JDP7_THEKO Predicted DNA methylase OS=Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.0 0.00022 0.03 2 73 .. 53 119 .. 52 139 .. 0.82 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 0.00022 Methyltransf_12 2 eiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvas 73 ++G+GtG l ++++v+ +++a+e a+e ++ + +++++ + d+++ +D+v+++ tr|Q5JDP7|Q5JDP7_THEKO 53 DLGAGTGVLGIGAVLL-GAENVYAVERDKEALEIARENARSLG--VEDKIEFVNADVSEFS--VNVDTVIMN 119 89*****999888777.556777*********99999888887..5679999999987544..49*****97 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (99 nodes) Target sequences: 2301 (637680 residues searched) Passed MSV filter: 86 (0.0373751); expected 46.0 (0.02) Passed bias filter: 83 (0.0360713); expected 46.0 (0.02) Passed Vit filter: 30 (0.0130378); expected 2.3 (0.001) Passed Fwd filter: 17 (0.00738809); expected 0.0 (1e-05) Initial search space (Z): 2301 [actual number of targets] Domain search space (domZ): 17 [number of targets reported over threshold] # CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.01 # Mc/sec: 6313.03 // [ok]