# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/Methyltransf_12.hmm.txt
# target sequence database:        proteomes/Thermococcus_kodakarensis.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       Methyltransf_12  [M=99]
Accession:   PF08242.11
Description: Methyltransferase domain
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
    3.2e-15   53.8   0.0    5.1e-15   53.1   0.0    1.3  1  tr|Q5JHQ2|Q5JHQ2_THEKO  SAM-dependent methyltransferase, UbiE
    5.9e-15   52.9   0.0    8.5e-15   52.4   0.0    1.2  1  tr|Q5JG68|Q5JG68_THEKO  SAM-dependent methyltransferase, UbiE
    2.6e-14   50.9   0.0    4.6e-14   50.1   0.0    1.4  1  tr|Q5JGN8|Q5JGN8_THEKO  SAM-dependent methyltransferase, UbiE
    2.2e-12   44.7   0.0    3.1e-12   44.2   0.0    1.2  1  tr|Q5JFS6|Q5JFS6_THEKO  Predicted SAM-dependent methyltransfe
    2.7e-12   44.4   0.0    3.2e-11   40.9   0.0    2.2  2  tr|Q5JED8|Q5JED8_THEKO  SAM-dependent methyltransferase, UbiE
    1.3e-11   42.2   0.0    2.5e-11   41.3   0.0    1.5  1  tr|Q5JFQ4|Q5JFQ4_THEKO  SAM-dependent methyltransferase, UbiE
    4.6e-10   37.2   0.0      8e-10   36.5   0.0    1.4  1  tr|Q5JG60|Q5JG60_THEKO  SAM-dependent methyltransferase, UbiE
    5.7e-06   24.1   0.0    9.2e-06   23.5   0.0    1.3  1  tr|Q5JJF0|Q5JJF0_THEKO  Ribosomal RNA small subunit methyltra
    0.00012   19.9   0.0    0.00038   18.3   0.0    1.9  1  tr|Q5JIX8|Q5JIX8_THEKO  N5-glutamine methyltransferase, HemK 
    0.00026   18.8   0.0      0.001   16.9   0.0    1.9  1  tr|Q5JID5|Q5JID5_THEKO  N2, N2-dimethylguanosine tRNA methylt
    0.00057   17.7   0.0     0.0017   16.1   0.0    1.7  2  tr|Q5JJ79|Q5JJ79_THEKO  Predicted SAM-dependent methyltransfe
    0.00069   17.4   0.0     0.0019   16.0   0.0    1.7  1  tr|Q5JGS7|Q5JGS7_THEKO  tRNA (1-methyladenosine) methyltransf
     0.0011   16.8   0.0      0.017   13.0   0.0    2.3  2  tr|Q5JF97|Q5JF97_THEKO  Chemotaxis protein methyltransferase 
     0.0021   15.9   0.1      0.021   12.7   0.0    2.6  2  tr|Q5JDB4|Q5JDB4_THEKO  tRNA/rRNA cytosine-C5-methylase, NOL1
     0.0063   14.3   0.0      0.022   12.6   0.0    1.9  2  tr|Q5JH73|Q5JH73_THEKO  Uncharacterized protein OS=Thermococc
  ------ inclusion threshold ------
      0.012   13.5   0.0        2.4    6.1   0.0    2.5  2  tr|Q5JDP5|Q5JDP5_THEKO  tRNA/rRNA cytosine-C5-methylase, NOL1
      0.019   12.8   0.0       0.03   12.2   0.0    1.3  1  tr|Q5JDP7|Q5JDP7_THEKO  Predicted DNA methylase OS=Thermococc


Domain annotation for each sequence (and alignments):
>> tr|Q5JHQ2|Q5JHQ2_THEKO  SAM-dependent methyltransferase, UbiE/COQ5 family OS=Thermococcus kodakarensis (strain ATCC B
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   53.1   0.0   3.8e-17   5.1e-15       1      99 []      43     138 ..      43     138 .. 0.89

  Alignments for each domain:
  == domain 1  score: 53.1 bits;  conditional E-value: 3.8e-17
         Methyltransf_12   1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhl..kdirea 85 
                             L++ cG+G +++ l++   + e++g+D s+ ++  +++++ak+++ ++++++ +a++l  +   +sfD+v+ ++ l h+  +d++++
  tr|Q5JHQ2|Q5JHQ2_THEKO  43 LDLACGVGGFSFLLEDL--GFEVVGLDNSRFML-EKAREFAKEKESRVEFIEGDARELPFEN--DSFDYVLFIDSLVHFepQDLAKV 124
                             89***************..**************.6666777777778888888888876544..6********************** PP

         Methyltransf_12  86 ldniyklLkpgGrl 99 
                             +++ +++LkpgG++
  tr|Q5JHQ2|Q5JHQ2_THEKO 125 FKETARVLKPGGKF 138
                             ************86 PP

>> tr|Q5JG68|Q5JG68_THEKO  SAM-dependent methyltransferase, UbiE/COQ5 family OS=Thermococcus kodakarensis (strain ATCC B
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.4   0.0   6.3e-17   8.5e-15       1      98 [.      40     131 ..      40     132 .. 0.86

  Alignments for each domain:
  == domain 1  score: 52.4 bits;  conditional E-value: 6.3e-17
         Methyltransf_12   1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.ssfDvvvasnvlhhlkdireal 86 
                             LeiG GtG +lr+  ++   +e++++D s++++e ak++ ++ +      v++++ ++++l+ + + fD+vv+s+v++ ++++++a+
  tr|Q5JG68|Q5JG68_THEKO  40 LEIGVGTGKTLRYYPQD---VELYAIDGSEKMLEMAKKRAKELGM----DVKFKVAEAESLPFPdDFFDTVVSSFVFCTVPEPERAI 119
                             8*************666...*************999999999996....455555554444444568******************** PP

         Methyltransf_12  87 dniyklLkpgGr 98 
                             ++i+++Lkp+G+
  tr|Q5JG68|Q5JG68_THEKO 120 EEIKRVLKPDGM 131
                             ***********7 PP

>> tr|Q5JGN8|Q5JGN8_THEKO  SAM-dependent methyltransferase, UbiE/COQ5 family OS=Thermococcus kodakarensis (strain ATCC B
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   50.1   0.0   3.4e-16   4.6e-14       1      99 []      46     141 ..      46     141 .. 0.92

  Alignments for each domain:
  == domain 1  score: 50.1 bits;  conditional E-value: 3.4e-16
         Methyltransf_12   1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvas.nvlhhl..kdire 84 
                             L++ cGtG  + +l+e+  + e++g+D++++++ + +++ a+ ++ n+++++ +ald++ ++    fD+v+++ + + ++    ire
  tr|Q5JGN8|Q5JGN8_THEKO  46 LDLACGTGIPTLELAER--GYEVLGLDLHEEML-RVARRKAEARGLNVKFIRGNALDISFEE---EFDAVTMFfSSIMYFddSAIRE 126
                             89***************..**************.7777777888899999999999988664...8*******9999999998999* PP

         Methyltransf_12  85 aldniyklLkpgGrl 99 
                             +++++++ L+pgG++
  tr|Q5JGN8|Q5JGN8_THEKO 127 LFNSVRRTLRPGGVF 141
                             *************86 PP

>> tr|Q5JFS6|Q5JFS6_THEKO  Predicted SAM-dependent methyltransferase OS=Thermococcus kodakarensis (strain ATCC BAA-918 /
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   44.2   0.0   2.3e-14   3.1e-12       1      99 []      62     155 ..      62     155 .. 0.87

  Alignments for each domain:
  == domain 1  score: 44.2 bits;  conditional E-value: 2.3e-14
         Methyltransf_12   1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhlkdireald 87 
                             L++GcGtG l+++++ k+    ++gvD  +++i    ++l +r  +n+++v+ + l+++ ld  ++fD vv s vlh + +++ +l+
  tr|Q5JFS6|Q5JFS6_THEKO  62 LDVGCGTGVLTFKMALKNGVEMVVGVDRKEEVI-EFCNRLGDRVTKNAKFVQGNFLEMG-LD--EKFDSVVFSYVLHDF-EPEPFLE 143
                             8****************6666667*********.8888888888888777777777754.44..49************7.9****** PP

         Methyltransf_12  88 niyklLkpgGrl 99 
                             ++ ++L  gGr+
  tr|Q5JFS6|Q5JFS6_THEKO 144 RALEVLEEGGRV 155
                             **********85 PP

>> tr|Q5JED8|Q5JED8_THEKO  SAM-dependent methyltransferase, UbiE/COQ5 family OS=Thermococcus kodakarensis (strain ATCC B
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.1   0.0      0.64        87      59      92 ..      78     111 ..      52     113 .. 0.76
   2 !   40.9   0.0   2.4e-13   3.2e-11       1      99 []     164     258 ..     164     258 .. 0.87

  Alignments for each domain:
  == domain 1  score: 1.1 bits;  conditional E-value: 0.64
         Methyltransf_12  59 ldldggssfDvvvasnvlhhl.kdirealdniykl 92 
                             ++l++  s  +vva++   +l  d++++l++iyk+
  tr|Q5JED8|Q5JED8_THEKO  78 IELAEF-SHNLVVAAERYGALvSDWASVLEEIYKM 111
                             334444.7778888887777789**********98 PP

  == domain 2  score: 40.9 bits;  conditional E-value: 2.4e-13
         Methyltransf_12   1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhlkdireald 87 
                             L+iGcG+ s +   +    +  y+g+D+s + ++ a++++a +       v l+++d+    + +s+Dvv++s+vl++++++++a++
  tr|Q5JED8|Q5JED8_THEKO 164 LDIGCGSVSPSYFGRLVGYNGFYLGLDYSYALLDIARARIAGEAL----PVVLKEIDATIIRPVNSYDVVIMSFVLEYIQNRKRAIK 246
                             89***9665555444444899************999999999986....8888888888777889********************** PP

         Methyltransf_12  88 niyklLkpgGrl 99 
                             n+ + L+ gG+l
  tr|Q5JED8|Q5JED8_THEKO 247 NALEGLREGGKL 258
                             **********97 PP

>> tr|Q5JFQ4|Q5JFQ4_THEKO  SAM-dependent methyltransferase, UbiE/COQ5 family OS=Thermococcus kodakarensis (strain ATCC B
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.3   0.0   1.8e-13   2.5e-11       1      99 []      44     132 ..      44     132 .. 0.80

  Alignments for each domain:
  == domain 1  score: 41.3 bits;  conditional E-value: 1.8e-13
         Methyltransf_12   1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhl..kdirea 85 
                             +++GcGtG++lr l+ +    +y+gv++s+ + ++ +ek  +      + ++   l++   +  +s D+vv+  ++hh+  +++ ea
  tr|Q5JFQ4|Q5JFQ4_THEKO  44 VDVGCGTGNILRFLRCE----RYIGVEPSEGMRKAFREKWGF------EPIDGHFLEIPLPE--GSADTVVSTYAFHHVpdEEKGEA 118
                             69************999....************444444433......34455555544322..3**************888888** PP

         Methyltransf_12  86 ldniyklLkpgGrl 99 
                             ++++ ++L+pgG+l
  tr|Q5JFQ4|Q5JFQ4_THEKO 119 IREMLRVLRPGGIL 132
                             ************87 PP

>> tr|Q5JG60|Q5JG60_THEKO  SAM-dependent methyltransferase, UbiE/COQ5 family OS=Thermococcus kodakarensis (strain ATCC B
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.5   0.0   5.9e-12     8e-10       2      99 .]      44     126 ..      43     126 .. 0.87

  Alignments for each domain:
  == domain 1  score: 36.5 bits;  conditional E-value: 5.9e-12
         Methyltransf_12   2 eiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhlkdirealdn 88 
                             eiG GtG+++++l  k      +gv++s+++ e a+++  + ++  ++n+ +e+         +s D+ ++  +++ ++d+++al++
  tr|Q5JG60|Q5JG60_THEKO  44 EIGVGTGRFAAPLGIK------LGVEPSKAMAEIARTRGIEVIEGTAENLPFEE---------DSMDYLLMVTTICFVDDPEKALKE 115
                             9***************......**********8888888887765555555542.........289********************* PP

         Methyltransf_12  89 iyklLkpgGrl 99 
                             +y++LkpgG l
  tr|Q5JG60|Q5JG60_THEKO 116 AYRVLKPGGAL 126
                             *********75 PP

>> tr|Q5JJF0|Q5JJF0_THEKO  Ribosomal RNA small subunit methyltransferase C OS=Thermococcus kodakarensis (strain ATCC BAA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.5   0.0   6.8e-08   9.2e-06       1      99 []      61     155 ..      61     155 .. 0.83

  Alignments for each domain:
  == domain 1  score: 23.5 bits;  conditional E-value: 6.8e-08
         Methyltransf_12   1 LeiGcGtGsllralleklpdieyt.gvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhl.kdirea 85 
                             L++GcG G +  +  +    ++y+  +D++++a+   ++k  k+++ +n++v++  l       g++fD ++ +  +h+  + +re+
  tr|Q5JJF0|Q5JJF0_THEKO  61 LDLGCGYGPIGIVASRF---VDYVvMTDVNRRAV-SIAKKNLKINGVRNAEVRWGSLYEP--VAGEKFDSIITNPPVHAGkEVLREI 141
                             8*******998888666...78777*********.6666666667788899999877744..4446********99999878889** PP

         Methyltransf_12  86 ldniyklLkpgGrl 99 
                             + n+ ++L++gG l
  tr|Q5JJF0|Q5JJF0_THEKO 142 VINAPRHLNDGGYL 155
                             ************86 PP

>> tr|Q5JIX8|Q5JIX8_THEKO  N5-glutamine methyltransferase, HemK family OS=Thermococcus kodakarensis (strain ATCC BAA-918
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.3   0.0   2.8e-06   0.00038       1      72 [.      39     104 ..      39     148 .. 0.77

  Alignments for each domain:
  == domain 1  score: 18.3 bits;  conditional E-value: 2.8e-06
         Methyltransf_12   1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvva 72 
                             L+ G+GtG ++  l++k     ++gvDi+p a+e a+e  a+++     nv+++  dl+++ +g  fDv++ 
  tr|Q5JIX8|Q5JIX8_THEKO  39 LDMGTGTGIIALLLARK--ARWVLGVDINPLAVELAREN-ARIN--GIINVEFRLSDLFENVSG-EFDVITF 104
                             89******999999999..77777*********444443.3333..245677777777766666.9999885 PP

>> tr|Q5JID5|Q5JID5_THEKO  N2, N2-dimethylguanosine tRNA methyltransferase OS=Thermococcus kodakarensis (strain ATCC BAA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.9   0.0   7.5e-06     0.001      11      99 .]     194     289 ..     188     289 .. 0.81

  Alignments for each domain:
  == domain 1  score: 16.9 bits;  conditional E-value: 7.5e-06
         Methyltransf_12  11 lralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvv......asnvlhhl......kdirea 85 
                             l +      +++++gvDi p+++e a++ l++++ ++ +    +a+ l+dl + ++f +v              l      +  r+a
  tr|Q5JID5|Q5JID5_THEKO 194 LIEAGLL--GLRVYGVDIRPEMVEGAETNLKHYGVRDYTLKLGDATRLEDLFPDKKFEAVAtdppygT---AATLagrkrdELYRKA 275
                             4444444..89**************************999999999999999999**99996664433...33335558877788** PP

         Methyltransf_12  86 ldniyklLkpgGrl 99 
                             l++iy++L +gGrl
  tr|Q5JID5|Q5JID5_THEKO 276 LRSIYNVLEDGGRL 289
                             ************97 PP

>> tr|Q5JJ79|Q5JJ79_THEKO  Predicted SAM-dependent methyltransferase, DUF890 family OS=Thermococcus kodakarensis (strain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.1   0.0   1.3e-05    0.0017       1      71 [.      86     156 ..      86     159 .. 0.73
   2 ?   -1.9   0.0       5.5   7.4e+02      85      98 ..     189     202 ..     186     203 .. 0.82

  Alignments for each domain:
  == domain 1  score: 16.1 bits;  conditional E-value: 1.3e-05
         Methyltransf_12   1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvv 71 
                             LeiG+G  ++++ ++e+l ++++t++++++++ e ak+ + k+++n      +  +  +  ++g+ fDv++
  tr|Q5JJ79|Q5JJ79_THEKO  86 LEIGTGHTAMMALMAERLFNCDVTATELDEEFFEYAKRNIEKNGANVKPIKSNGGIIRGVVPKGERFDVIF 156
                             899999999999999999***************88888888877644433333333333333338888886 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 5.5
         Methyltransf_12  85 aldniyklLkpgGr 98 
                             +++++ + L+pgG+
  tr|Q5JJ79|Q5JJ79_THEKO 189 LIEEALEYLNPGGK 202
                             67888999****98 PP

>> tr|Q5JGS7|Q5JGS7_THEKO  tRNA (1-methyladenosine) methyltransferase OS=Thermococcus kodakarensis (strain ATCC BAA-918 
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.0   0.0   1.4e-05    0.0019       2      98 ..      99     189 ..      98     190 .. 0.80

  Alignments for each domain:
  == domain 1  score: 16.0 bits;  conditional E-value: 1.4e-05
         Methyltransf_12   2 eiGcGtGsllrallekl.pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhlkdireald 87 
                             e G+G+G+l+  l+++  p+ +++ +++ +++ e ak+     +    ++v l++ ++ d   ++  D +v+      l++++ +l 
  tr|Q5JGS7|Q5JGS7_THEKO  99 EAGAGSGALTIFLANAVgPTGKVISYEVRKDFYEIAKKNVELAGF--SDRVVLKNKSIYDGIDEKEADHIVL-----DLPQPENVLP 178
                             89***************99**************888888877775..4566666666544444446666654.....349******* PP

         Methyltransf_12  88 niyklLkpgGr 98 
                             ++ ++L+pgG 
  tr|Q5JGS7|Q5JGS7_THEKO 179 HAVDVLRPGGY 189
                             *********97 PP

>> tr|Q5JF97|Q5JF97_THEKO  Chemotaxis protein methyltransferase OS=Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.0   0.0      0.66        90      18      35 ..     134     153 ..     112     167 .. 0.75
   2 !   13.0   0.0   0.00013     0.017      50      99 .]     193     244 ..     182     244 .. 0.80

  Alignments for each domain:
  == domain 1  score: 1.0 bits;  conditional E-value: 0.66
         Methyltransf_12  18 l..pdieytgvDispsaied 35 
                             l   +++++++Di+++a++ 
  tr|Q5JF97|Q5JF97_THEKO 134 LkrYRLKILATDIDREALNT 153
                             14458999*******99943 PP

  == domain 2  score: 13.0 bits;  conditional E-value: 0.00013
         Methyltransf_12  50 nvnlealdlldldggssfDvvvasnvlhhl..kdirealdniyklLkpgGrl 99 
                              v++++ +ll++  +  fD++++ nvl ++  +  +e+++++y+ L + G l
  tr|Q5JF97|Q5JF97_THEKO 193 YVEFRHFNLLSDRYPTGFDMIFIRNVLIYMtkEAQEEVFKKLYNSLEDHGYL 244
                             5667777777666668***************66666**********999976 PP

>> tr|Q5JDB4|Q5JDB4_THEKO  tRNA/rRNA cytosine-C5-methylase, NOL1/NOP2/Sun family, fused to N-terminal NusB regulator dom
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.7   0.0       9.4   1.3e+03      23      49 ..     127     153 ..     108     160 .. 0.58
   2 !   12.7   0.0   0.00015     0.021       1      72 [.     266     335 ..     266     384 .. 0.68

  Alignments for each domain:
  == domain 1  score: -2.7 bits;  conditional E-value: 9.4
         Methyltransf_12  23 ytgvDispsaiedakeklakrennnnn 49 
                              +  +i +  +e+a ++l+++++  + 
  tr|Q5JDB4|Q5JDB4_THEKO 127 ALMHEIEKFDVERALKRLKEKDRIEWL 153
                             444455555566677777766665555 PP

  == domain 2  score: 12.7 bits;  conditional E-value: 0.00015
         Methyltransf_12   1 LeiGcGtGsllrallekl.pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvva 72 
                             L++ +  Gs +++ ++      e+++vD+s + + + kek +  + +n+ +v+ + ++  d+   ++fD +++
  tr|Q5JDB4|Q5JDB4_THEKO 266 LDLAAAPGSKTFHAAALMeNKGEIVAVDYSYDRLMRMKEKAKVLGVKNVRFVHADGQSFRDK---EKFDKIIL 335
                             7888888998999888886799************9999999999987777777777775544...47777763 PP

>> tr|Q5JH73|Q5JH73_THEKO  Uncharacterized protein OS=Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.6   0.0   0.00016     0.022       2      59 ..      89     144 ..      88     157 .. 0.82
   2 ?   -2.0   0.0       5.7   7.8e+02      65      94 ..     269     300 ..     238     302 .. 0.66

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 0.00016
         Methyltransf_12   2 eiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdll 59 
                             ++ cG G  l   ++k    + +g+Di+p  ie a++   k++  n +++n + l+ +
  tr|Q5JH73|Q5JH73_THEKO  89 DVSCGIGIQLIFYAMK--VERAYGIDIDPLKIEFARRNAEKYGVSNIEFINADSLSPE 144
                             899**********999..9999**************9999999877777777666544 PP

  == domain 2  score: -2.0 bits;  conditional E-value: 5.7
         Methyltransf_12  65 ssfDvv.vasnvlhhl.kdirealdniyklLk 94 
                             +s D++ ++++++h l  + r +l++ +++L+
  tr|Q5JH73|Q5JH73_THEKO 269 QSIDYAdLINELFHRLpVEARMLLREKRRVLA 300
                             56666623558888886666677777777776 PP

>> tr|Q5JDP5|Q5JDP5_THEKO  tRNA/rRNA cytosine-C5-methylase, NOL1/NOP2/Sun family OS=Thermococcus kodakarensis (strain AT
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.1   0.0     0.018       2.4       8      69 ..     262     324 ..     255     333 .. 0.79
   2 ?    4.7   0.0     0.047       6.4      82      99 .]     359     376 ..     351     376 .. 0.86

  Alignments for each domain:
  == domain 1  score: 6.1 bits;  conditional E-value: 0.018
         Methyltransf_12   8 Gsllrallekl.pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDv 69 
                             G  +++++e    + ++++ D++++ i++ ke l++ + + ++ ++ + +++ +l g++  D 
  tr|Q5JDP5|Q5JDP5_THEKO 262 GGKTAHMAELMeNRGKIYAFDVDSARIKRMKEVLKRTGVEIAEVIKADGRNAPELLGEEIADR 324
                             44444444444357***********************99999999999999999888766665 PP

  == domain 2  score: 4.7 bits;  conditional E-value: 0.047
         Methyltransf_12  82 irealdniyklLkpgGrl 99 
                              +e+++++ klLkpgGrl
  tr|Q5JDP5|Q5JDP5_THEKO 359 QKELMESAWKLLKPGGRL 376
                             568999**********97 PP

>> tr|Q5JDP7|Q5JDP7_THEKO  Predicted DNA methylase OS=Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   0.00022      0.03       2      73 ..      53     119 ..      52     139 .. 0.82

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 0.00022
         Methyltransf_12   2 eiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvas 73 
                             ++G+GtG l           ++++v+ +++a+e a+e  ++ +    +++++ + d+++      +D+v+++
  tr|Q5JDP7|Q5JDP7_THEKO  53 DLGAGTGVLGIGAVLL-GAENVYAVERDKEALEIARENARSLG--VEDKIEFVNADVSEFS--VNVDTVIMN 119
                             89*****999888777.556777*********99999888887..5679999999987544..49*****97 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (99 nodes)
Target sequences:                         2301  (637680 residues searched)
Passed MSV filter:                        86  (0.0373751); expected 46.0 (0.02)
Passed bias filter:                       83  (0.0360713); expected 46.0 (0.02)
Passed Vit filter:                        30  (0.0130378); expected 2.3 (0.001)
Passed Fwd filter:                        17  (0.00738809); expected 0.0 (1e-05)
Initial search space (Z):               2301  [actual number of targets]
Domain search space  (domZ):              17  [number of targets reported over threshold]
# CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.01
# Mc/sec: 6313.03
//
[ok]