# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/Methyltransf_12.hmm.txt # target sequence database: proteomes/Trypanosoma_brucei.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: Methyltransf_12 [M=99] Accession: PF08242.11 Description: Methyltransferase domain Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.6e-12 45.0 0.0 1.2e-11 44.2 0.0 1.4 1 tr|Q38DV8|Q38DV8_TRYB2 Ubiquinone biosynthesis O-methyltrans 2.5e-11 43.1 0.0 9.4e-11 41.3 0.0 2.0 1 tr|Q38DL9|Q38DL9_TRYB2 Methyltransferase-like protein OS=Try 1.2e-09 37.7 0.0 3e-09 36.5 0.0 1.7 1 tr|Q387X1|Q387X1_TRYB2 Uncharacterized protein OS=Trypanosom 4.6e-09 35.9 0.0 0.0038 16.9 0.0 2.7 2 tr|Q38FT0|Q38FT0_TRYB2 Uncharacterized protein OS=Trypanosom 9e-08 31.7 0.0 0.00031 20.4 0.0 2.7 2 tr|Q57UL4|Q57UL4_TRYB2 Uncharacterized protein OS=Trypanosom 1.6e-07 30.9 0.0 2.6e-07 30.3 0.0 1.3 1 tr|Q383M8|Q383M8_TRYB2 2-methoxy-6-polyprenyl-1,4-benzoquino 1.7e-07 30.9 0.0 4e-07 29.7 0.0 1.7 1 tr|Q584Q2|Q584Q2_TRYB2 DREV methyltransferase, putative OS=T 2.6e-07 30.3 0.0 4.3e-07 29.5 0.0 1.4 1 tr|Q4FKP8|Q4FKP8_TRYB2 mRNA capping methyltransferase, putat 1.6e-06 27.7 0.0 1.1e-05 25.0 0.0 2.2 1 tr|Q38C62|Q38C62_TRYB2 Methyltransferase-like protein OS=Try 1.8e-06 27.5 0.0 0.00012 21.8 0.0 2.3 1 tr|Q583K3|Q583K3_TRYB2 Uncharacterized protein OS=Trypanosom 3.8e-06 26.5 0.0 8.5e-06 25.4 0.0 1.6 1 tr|Q4GYA9|Q4GYA9_TRYB2 Arginine N-methyltransferase, putativ 1.3e-05 24.8 0.0 4.3e-05 23.1 0.0 1.9 1 tr|Q38AK8|Q38AK8_TRYB2 Uncharacterized protein OS=Trypanosom 2e-05 24.2 0.0 3.1e-05 23.6 0.0 1.3 1 tr|Q584S3|Q584S3_TRYB2 Uncharacterized protein OS=Trypanosom 2.5e-05 23.9 0.1 0.00027 20.6 0.1 2.2 1 tr|Q388Y3|Q388Y3_TRYB2 Uncharacterized protein OS=Trypanosom 3.6e-05 23.4 0.0 7.6e-05 22.3 0.0 1.6 1 tr|Q38D36|Q38D36_TRYB2 Uncharacterized protein OS=Trypanosom 8.2e-05 22.2 0.0 0.00046 19.8 0.0 2.2 2 tr|Q384Z7|Q384Z7_TRYB2 Uncharacterized protein OS=Trypanosom 9.3e-05 22.1 0.0 0.00015 21.4 0.0 1.4 1 tr|Q57XQ9|Q57XQ9_TRYB2 Uncharacterized protein OS=Trypanosom 0.00012 21.7 0.0 0.00018 21.1 0.0 1.3 1 tr|Q38EP1|Q38EP1_TRYB2 Uncharacterized protein OS=Trypanosom 0.00012 21.6 0.0 0.00056 19.6 0.0 2.0 2 tr|Q38BP3|Q38BP3_TRYB2 Arginine N-methyltransferase, putativ 0.00017 21.2 0.0 0.0011 18.6 0.0 2.1 2 tr|Q4FKJ2|Q4FKJ2_TRYB2 Methyltransferase OS=Trypanosoma bruc 0.00032 20.3 0.1 0.0011 18.6 0.1 2.0 1 tr|Q389Z0|Q389Z0_TRYB2 Uncharacterized protein OS=Trypanosom 0.00055 19.6 0.0 0.0012 18.4 0.0 1.6 1 tr|Q585P9|Q585P9_TRYB2 rRNA adenine N(6)-methyltransferase O 0.0006 19.5 0.0 0.0049 16.5 0.0 2.4 2 tr|Q38EH6|Q38EH6_TRYB2 Spermidine synthase, putative OS=Tryp 0.0018 17.9 0.0 0.0072 16.0 0.0 2.1 1 tr|Q38BY6|Q38BY6_TRYB2 Uncharacterized protein OS=Trypanosom 0.0021 17.7 0.0 0.0066 16.1 0.0 1.8 2 tr|Q38E77|Q38E77_TRYB2 tRNA (guanine-N(7)-)-methyltransferas 0.003 17.2 0.0 0.0048 16.6 0.0 1.5 1 tr|Q57YX1|Q57YX1_TRYB2 Uncharacterized protein OS=Trypanosom 0.0035 17.0 0.0 0.0064 16.2 0.0 1.4 1 tr|Q57WE9|Q57WE9_TRYB2 Protein arginine methyltransferase ND 0.0041 16.8 0.0 0.017 14.8 0.0 2.1 1 tr|Q582P2|Q582P2_TRYB2 Uncharacterized protein OS=Trypanosom 0.0058 16.3 0.0 0.012 15.2 0.0 1.6 1 tr|Q4GYR8|Q4GYR8_TRYB2 Uncharacterized protein OS=Trypanosom 0.0088 15.7 0.0 0.015 15.0 0.0 1.4 1 tr|Q4GZF2|Q4GZF2_TRYB2 Histone-lysine N-methyltransferase, H ------ inclusion threshold ------ 0.012 15.3 0.0 0.021 14.5 0.0 1.5 1 tr|Q389B6|Q389B6_TRYB2 Uncharacterized protein OS=Trypanosom 0.013 15.2 0.0 0.023 14.4 0.0 1.4 1 tr|Q581Z0|Q581Z0_TRYB2 Histone-lysine N-methyltransferase, H 0.014 15.1 0.0 0.03 14.0 0.0 1.6 1 tr|Q38BN0|Q38BN0_TRYB2 rRNA adenine N(6)-methyltransferase O 0.015 14.9 0.0 0.078 12.7 0.0 2.1 2 sp|Q582G4|ANM7_TRYB2 Protein arginine N-methyltransferase 0.016 14.9 0.1 0.035 13.8 0.1 1.7 1 tr|Q381Q6|Q381Q6_TRYB2 Uncharacterized protein OS=Trypanosom 0.016 14.9 0.0 1.9 8.2 0.0 2.5 2 tr|Q383B4|Q383B4_TRYB2 tRNA (adenine(58)-N(1))-methyltransfe 0.031 14.0 0.2 1.6 8.5 0.0 3.1 2 tr|Q385R2|Q385R2_TRYB2 Uncharacterized protein OS=Trypanosom 0.068 12.9 0.1 0.26 11.0 0.1 1.9 1 tr|Q38AH9|Q38AH9_TRYB2 Protein-L-isoaspartate, putative OS=T Domain annotation for each sequence (and alignments): >> tr|Q38DV8|Q38DV8_TRYB2 Ubiquinone biosynthesis O-methyltransferase, mitochondrial OS=Trypanosoma brucei brucei (stra # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 44.2 0.0 5.2e-14 1.2e-11 1 99 [] 71 171 .. 71 171 .. 0.87 Alignments for each domain: == domain 1 score: 44.2 bits; conditional E-value: 5.2e-14 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsai....edakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhlkdir 83 L++GcG G l++ +++ + +++g+D +++i e++++ l+++ ++ ++ l+ + +g +f +vvas+v++h+ d + tr|Q38DV8|Q38DV8_TRYB2 71 LDVGCGGGILSESIARL--GGDVLGIDMCKESIavaeERRQRVLRDITPQASLAYRCVPLHEVVEGEGRQFELVVASEVIEHVSDAA 155 8****************..**************66655555566777777777777777777777677******************* PP Methyltransf_12 84 ealdniyklLkpgGrl 99 ++l+ i ++ kpgG+l tr|Q38DV8|Q38DV8_TRYB2 156 AFLHDICAATKPGGVL 171 **************97 PP >> tr|Q38DL9|Q38DL9_TRYB2 Methyltransferase-like protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=18543 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 41.3 0.0 4.2e-13 9.4e-11 1 99 [] 90 209 .. 90 209 .. 0.96 Alignments for each domain: == domain 1 score: 41.3 bits; conditional E-value: 4.2e-13 Methyltransf_12 1 LeiGcGtGsllrallekl...pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg................ssfD 68 +e GcG+G+ ++++l++ ++++++g Dis+ ai+ +ek + + ++++ +l+ ++d + +D tr|Q38DL9|Q38DL9_TRYB2 90 MEAGCGVGNAVFPILKDYgdvSGWRVVGFDISTVAIKLLREKQNTLPHVEQEKFTAWVLNPVEQDIApiitasvarqsrprgdGLVD 176 699*********************************9999999999999999999999999999999******************** PP Methyltransf_12 69 vvvasnvlhhl..kdirealdniyklLkpgGrl 99 v +++vl+ + ++ + +l++i++++k gG++ tr|Q38DL9|Q38DL9_TRYB2 177 FVSMIFVLCSIpvEEHAVVLRRIAACMKEGGVF 209 ***********999999**************86 PP >> tr|Q387X1|Q387X1_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 36.5 0.0 1.3e-11 3e-09 1 99 [] 63 167 .. 63 167 .. 0.91 Alignments for each domain: == domain 1 score: 36.5 bits; conditional E-value: 1.3e-11 Methyltransf_12 1 LeiGcGtGsllrallekl...pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg....ssfDvvvasnvlhhlk 80 Le+G+ tG + r++lek +y+ +D+ ++ +++ e++++ ++ ++++v++ + + + ++ ++D+vv++ +h+++ tr|Q387X1|Q387X1_TRYB2 63 LEVGAHTGWFFRHMLEKQqlfGLKQYIQTDVCEERLNRNYEEIKHLIPPDVEFVQICCDEEEPSP-FgipeRTVDMVVSCLSMHWVN 148 8*****************999999***********************999888888877744333.36******************* PP Methyltransf_12 81 direaldniyklLkpgGrl 99 d++ a+ ni+k+Lk++G l tr|Q387X1|Q387X1_TRYB2 149 DLETAMVNIRKVLKKDGFL 167 *****************86 PP >> tr|Q38FT0|Q38FT0_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.9 0.0 1.7e-05 0.0038 1 54 [. 140 191 .. 140 199 .. 0.85 2 ! 16.1 0.0 3e-05 0.0067 50 99 .] 217 295 .. 208 295 .. 0.81 Alignments for each domain: == domain 1 score: 16.9 bits; conditional E-value: 1.7e-05 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnle 54 L++Gc +G+ + ++ ++ ++++g+D+s ++i+ a++ ++ n n + +++e tr|Q38FT0|Q38FT0_TRYB2 140 LDLGCAVGASSLEMSKY--FSRVVGIDYSVAFIKMARNVVQSALNPNIQPIKYE 191 8****************..**************888887777777666666665 PP == domain 2 score: 16.1 bits; conditional E-value: 3e-05 Methyltransf_12 50 nvnlealdlldldgg.............................ssfDvvvasnvlhhlkdirealdniyklLkpgGrl 99 +++ +a +lld+dg + fD+v+++n+l+ ++++r++ld + lL+ gG+l tr|Q38FT0|Q38FT0_TRYB2 217 FYRGDAMNLLDSDGDdgrghivppvhhgdtndeditswyrvpsgERFDAVLVANLLCRVPNPRKLLDMLPLLLVSGGIL 295 556666666666666667777777777777777788888999999********************************86 PP >> tr|Q57UL4|Q57UL4_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.5 0.0 0.007 1.6 1 45 [. 86 153 .. 86 176 .. 0.83 2 ! 20.4 0.0 1.4e-06 0.00031 44 99 .] 279 332 .. 254 332 .. 0.72 Alignments for each domain: == domain 1 score: 8.5 bits; conditional E-value: 0.007 Methyltransf_12 1 LeiGcGtGsllrallekl.......................pdieytgvDispsaiedakeklakren 45 Le+G+G G +l++ + +e++ +D sp +i+ ++e+ +r + tr|Q57UL4|Q57UL4_TRYB2 86 LEVGAGCGGVLSYYDAVVssasdpptvngsteedhaaikqnTVTEVVLCDRSPGMIQSTAEQVYRRYG 153 899******99999999999999999999999999999998899************777777655544 PP == domain 2 score: 20.4 bits; conditional E-value: 1.4e-06 Methyltransf_12 44 ennnnnnvnlealdlldldggssfDvvv.asnvlhhlkdirealdniyklLkpgGrl 99 +n+ ++ n+ a+++ +d +sfD+vv +++++++ +d+ +al+++ +++kp+G+l tr|Q57UL4|Q57UL4_TRYB2 279 KNQTFSVANYAAEQMPFSD--NSFDTVVdMFGLCSY-DDPVRALREMSRVCKPDGHL 332 3333444444444444333..6******66677777.******************97 PP >> tr|Q383M8|Q383M8_TRYB2 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial OS=Trypanosoma brucei brucei # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.3 0.0 1.2e-09 2.6e-07 1 99 [] 62 173 .. 62 173 .. 0.94 Alignments for each domain: == domain 1 score: 30.3 bits; conditional E-value: 1.2e-09 Methyltransf_12 1 LeiGcGtGsllrallekl...............pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvva 72 +++ +GtG++++++ ++ +++ +t+vDi++++++ +++ a+++ + +++ ++l +d +fD ++ tr|Q383M8|Q383M8_TRYB2 62 VDVAGGTGDIAFRIIDEVrqlerglpgltppdfRGVGVTVVDINEQMVHEGEARAAREGYDGLEWIVASGEELPLDDM--QFDGYTV 146 5999********************************************999999999999999999999888876665..9****** PP Methyltransf_12 73 snvlhhlkdirealdniyklLkpgGrl 99 s+ l ++ d+ +al++++++Lk gG+l tr|Q383M8|Q383M8_TRYB2 147 SFGLRNFSDRPKALREAHRVLKVGGVL 173 *************************87 PP >> tr|Q584Q2|Q584Q2_TRYB2 DREV methyltransferase, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.7 0.0 1.8e-09 4e-07 1 99 [] 123 212 .. 123 212 .. 0.91 Alignments for each domain: == domain 1 score: 29.7 bits; conditional E-value: 1.8e-09 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhlkdireald 87 L++G+G+G ++++l + ++t++++s + +l +r+ + + ++++++++ ++Dv+ ++nvl + + ++l+ tr|Q584Q2|Q584Q2_TRYB2 123 LDVGAGDGGVTSRLQPL--FKRVTATEFSIPMR----WRLWRRGYEVLPYQDPFTNKDGSR---RYYDVISCLNVLDRADRPLDLLA 200 8****************..*************9....999999987777777777776655...4********************** PP Methyltransf_12 88 niyklLkpgGrl 99 ++++ L p+G+l tr|Q584Q2|Q584Q2_TRYB2 201 SMRDSLGPEGIL 212 **********86 PP >> tr|Q4FKP8|Q4FKP8_TRYB2 mRNA capping methyltransferase, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.5 0.0 1.9e-09 4.3e-07 18 99 .] 100 200 .. 71 200 .. 0.87 Alignments for each domain: == domain 1 score: 29.5 bits; conditional E-value: 1.9e-09 Methyltransf_12 18 l....pdieyt.gvDispsaiedakeklakrennnnnnvnlealdlldldgg..........ssfDvvvasnvlhhl....kdirea 85 + y+ ++D+sp+ i+ a+ + +k+ ++ + ++ + + d +++d ++fD+v + +++h+ + i+ + tr|Q4FKP8|Q4FKP8_TRYB2 100 PrerlTKAAYVeCYDVSPECIAEAESRYKKIAPDTVCRCSFTVKDCFSEDFLlrelpltqhfGKFDIVSIQFAFHYAcdtlERIDML 186 044457889999*********************************9999998*********************************** PP Methyltransf_12 86 ldniyklLkpgGrl 99 l i+++L+p+G++ tr|Q4FKP8|Q4FKP8_TRYB2 187 LGAIARALAPEGVF 200 ************86 PP >> tr|Q38C62|Q38C62_TRYB2 Methyltransferase-like protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=18543 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.0 0.0 4.8e-08 1.1e-05 2 99 .] 122 252 .. 121 252 .. 0.89 Alignments for each domain: == domain 1 score: 25.0 bits; conditional E-value: 4.8e-08 Methyltransf_12 2 eiGcGtGsllrallekl.pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg....................... 64 e GcGtGs+l ++ +++ +++++g D+s++a+ + e+ + + +++++ dl + tr|Q38C62|Q38C62_TRYB2 122 ECGCGTGSTLLPIMNQFkDGVHFIGFDVSTAAVSALLEHPIASDFSAEGRLTVFPYDLCYG--Rvsasedcrrtkfktecgtlkttl 206 89***************889*************8888888888888888999999998754..34589999**************** PP Methyltransf_12 65 ........ssfDvvvasnvlhhl...kdirealdniyklLkpgGrl 99 + +D++++ +vl+ l + + al +i++ L ++G+l tr|Q38C62|Q38C62_TRYB2 207 lekvpgcsKGVDAAILVFVLSSLptiECMLYALTEIKSILHNDGIL 252 ***********************77788888888999999999976 PP >> tr|Q583K3|Q583K3_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.8 0.0 5.1e-07 0.00012 1 79 [. 56 185 .. 56 216 .. 0.63 Alignments for each domain: == domain 1 score: 21.8 bits; conditional E-value: 5.1e-07 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsai..edakeklakrennnnnnvnlealdlldldgg..................... 64 L++GcG+G ++l+e + + +g+Dis++++ ++a+e+l ++++++ ++ +e dl d g tr|Q583K3|Q583K3_TRYB2 56 LDVGCGSGLSGEVLREC--GHTWIGIDISTDMLgmAKASEELMREDDEKEDEGPIEGVDLRDVRWGpihdenenenenddhdstdgd 140 8****************..9999**********998888888888777666555554444444444455555555555555555555 PP Methyltransf_12 65 ..............................ssfDvvvasnvlhhl 79 ++fD +v+++++++l tr|Q583K3|Q583K3_TRYB2 141 gneaeavlppgpsivevmrgdmgeglpfrpGAFDGAVSISAVQWL 185 555555555555555555555555555555555555555555555 PP >> tr|Q4GYA9|Q4GYA9_TRYB2 Arginine N-methyltransferase, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.4 0.0 3.8e-08 8.5e-06 1 72 [. 58 125 .. 58 142 .. 0.80 Alignments for each domain: == domain 1 score: 25.4 bits; conditional E-value: 3.8e-08 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvva 72 L++GcGtG l++ +++ +++gvD s+ a+ +a+e ++++ +++ + + + ++ld +++D++++ tr|Q4GYA9|Q4GYA9_TRYB2 58 LDVGCGTGILSMFAAKA-GARKVIGVDCSTVAV-QAREIVRDNGFEDVITIIQGKVEEIQLD--EKVDIIIS 125 8**********999999.777888*********.9999999999766544444444445555..59999984 PP >> tr|Q38AK8|Q38AK8_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.1 0.0 1.9e-07 4.3e-05 1 98 [. 70 200 .. 70 201 .. 0.74 Alignments for each domain: == domain 1 score: 23.1 bits; conditional E-value: 1.9e-07 Methyltransf_12 1 LeiGcGtGsllrallekl..................pdieyt.gvDispsaiedakeklakrennnnnnvnlealdlldldgg.... 64 +++GcG+G + + + p +++ gvD+s++ + a ++l ++ + + tr|Q38AK8|Q38AK8_TRYB2 70 VDVGCGNGKYFSCAQNFMaatsnapddganeegqtgPAYRFVaGVDFSERLLRLALNQLDHEASETSPSSSRSLGT------Rgrte 150 59******988777666688999************99999999*********444444444443222222222222......12345 PP Methyltransf_12 65 .............ssfDvvvasnvlhhl...kdirealdniyklLkpgGr 98 ++fD+++++ v+hh+ + + +a++++ +l++p+G tr|Q38AK8|Q38AK8_TRYB2 151 llladarrtafrnGAFDAAISIAVVHHFathERRLDAVRELLRLVRPDGL 200 66888899********************7755555777788888888886 PP >> tr|Q584S3|Q584S3_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.6 0.0 1.4e-07 3.1e-05 1 98 [. 94 188 .. 94 189 .. 0.89 Alignments for each domain: == domain 1 score: 23.6 bits; conditional E-value: 1.4e-07 Methyltransf_12 1 LeiGcGtGsllralleklpdieyt.gvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhl..kdire 84 L+ G+G G++++ ll + ++t +++ +s++e+ake+l ++ + e+ +l + +++D++v+ + +l +d + tr|Q584S3|Q584S3_TRYB2 94 LDCGAGIGRITKSLLCH--LYDVTdLLEPVASMLEKAKEELEGFPVGDFFQSSMETAKLQ---P-KTYDLIVIQWAAIYLtdEDFVA 174 899**************..888899********************988888888877753...4.4********77777779***** PP Methyltransf_12 85 aldniyklLkpgGr 98 +l +++++L+p G tr|Q584S3|Q584S3_TRYB2 175 FLVRCKEALTPKGY 188 ***********997 PP >> tr|Q388Y3|Q388Y3_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.6 0.1 1.2e-06 0.00027 2 86 .. 42 168 .. 41 179 .. 0.80 Alignments for each domain: == domain 1 score: 20.6 bits; conditional E-value: 1.2e-06 Methyltransf_12 2 eiGcGtGsllrallekl....pdieytgvDispsaiedakeklakrennn......nnnvnlealdlldldgg.............. 64 + Gc +G llr++l + + ++ +++D+++ a++ ake + + + + +v++ + dl tr|Q388Y3|Q388Y3_TRYB2 42 DAGCSSGGLLRHILTSQlqehSFSRALAIDLDKVALHEAKEAITALGFSSpvallhPMHVEFVQGDL-----Tkppvftpfeedker 123 89**************99*999**************9999999988865400000034455555554.....044568********* PP Methyltransf_12 65 .....................ssfDvvvasnvlhhl..kdireal 86 +++D+v++++vl+h+ d+ + tr|Q388Y3|Q388Y3_TRYB2 124 ereigkeatqlgeavprtqlsHQYDAVISIEVLEHInvSDVPLFT 168 ***********************************9776665555 PP >> tr|Q38D36|Q38D36_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.3 0.0 3.4e-07 7.6e-05 1 98 [. 205 299 .. 205 300 .. 0.86 Alignments for each domain: == domain 1 score: 22.3 bits; conditional E-value: 3.4e-07 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhlkdireald 87 Le+ +G G+++ a + e++ +D +++++++ + ++ + + + +++ ++l+ + + fD vv + l+ l d+ +al+ tr|Q38D36|Q38D36_TRYB2 205 LELAAGHGQNIGAYPYA--VHEIVMCDANAQQLQAIRYRIPQTAYPKYDVRRVRSENLEMFAD-GEFDCVVDMFGLCSLHDPLKALR 288 89999999999999888..99******************999887777777777666554444.49*****99999999******** PP Methyltransf_12 88 niyklLkpgGr 98 ++ +++k G tr|Q38D36|Q38D36_TRYB2 289 QMQRVVKSSGL 299 *******9986 PP >> tr|Q384Z7|Q384Z7_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.0 0.0 6.5 1.5e+03 19 73 .. 448 499 .. 435 512 .. 0.63 2 ! 19.8 0.0 2e-06 0.00046 1 99 [] 819 930 .. 819 930 .. 0.86 Alignments for each domain: == domain 1 score: -1.0 bits; conditional E-value: 6.5 Methyltransf_12 19 pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvas 73 ++ ++ +vD+ + +i + ++ +++ n v + + + s+ D+v++ tr|Q384Z7|Q384Z7_TRYB2 448 SEGDVFCVDVKTGSISALPDYFRGLGGRAKNSVFSAVVASSYR---SYLDYVIIV 499 3777888888888887777777777765544444444443322...588888876 PP == domain 2 score: 19.8 bits; conditional E-value: 2e-06 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg............ssfDvvvasnv 75 Lei cG G llr++ ++ ++++y+g D+ +s++ da+ +l + ++ +++ + + +d + +f v++a+ tr|Q384Z7|Q384Z7_TRYB2 819 LEICCG-GYLLRKWIRN-KTARYIGFDLKSSVV-DAASELISSLRHEMTEMSFYDVICADVFSAnfwshhltkihpRQFHVITAFAG 902 899999.6666665555.5**************.777777777778888888888887877777899******************99 PP Methyltransf_12 76 lhhl...kdir.ealdniyklLkpgGrl 99 +hh + ++ +++++++++L pgG++ tr|Q384Z7|Q384Z7_TRYB2 903 FHHAfgtEYTAmRLIESVANALIPGGVF 930 99999*977777**************86 PP >> tr|Q57XQ9|Q57XQ9_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.4 0.0 6.9e-07 0.00015 1 99 [] 47 157 .. 47 157 .. 0.87 Alignments for each domain: == domain 1 score: 21.4 bits; conditional E-value: 6.9e-07 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.....ssfDvvvasnvlhhl... 79 L +GcG+++l+ + e+l ++t vD+sp +i + ++ + ++ ++ +++l ++ ++l + fD v+ +++ ++ tr|Q57XQ9|Q57XQ9_TRYB2 47 LVVGCGNSRLSPCMYEHLNVRKITNVDVSPTVISQMTRRYKGMDEMRWICCDLIHTAPDKLLTLlcpedALFDFVIDKGLVDATlgg 133 569******************************8888888887777777777776666555544********************999 PP Methyltransf_12 80 ....kdirealdniyklLkpgGrl 99 ++ + +n+++++k+gGr+ tr|Q57XQ9|Q57XQ9_TRYB2 134 snsfHNLYTLTKNLARVMKNGGRF 157 99999999999***********86 PP >> tr|Q38EP1|Q38EP1_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.1 0.0 7.9e-07 0.00018 1 94 [. 70 179 .. 70 182 .. 0.88 Alignments for each domain: == domain 1 score: 21.1 bits; conditional E-value: 7.9e-07 Methyltransf_12 1 LeiGcGtGsllrallekl......pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhl.. 79 L++G+G++sl + l e+ ++ +++D+ p++ie+ + k + + n++++ ++++l++ + + fD+v+ +++ ++ tr|Q38EP1|Q38EP1_TRYB2 70 LHLGTGNSSLCMDLYEAVrerqlpFALHQVAMDYAPNVIERMQSKYSPDILPNAQWIVGDVRKLEEFREYGPFDAVIEKGTMDAIea 156 789***************999996689999********************99999999999998877777***************98 PP Methyltransf_12 80 ........kdirealdniyklLk 94 d++++l+ + lLk tr|Q38EP1|Q38EP1_TRYB2 157 dknrpemkGDVEAMLHGVDTLLK 179 87777777777777777777776 PP >> tr|Q38BP3|Q38BP3_TRYB2 Arginine N-methyltransferase, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.9 0.0 5.8 1.3e+03 4 18 .. 66 80 .. 64 105 .. 0.76 2 ! 19.6 0.0 2.5e-06 0.00056 1 73 [. 146 216 .. 146 245 .. 0.79 Alignments for each domain: == domain 1 score: -0.9 bits; conditional E-value: 5.8 Methyltransf_12 4 GcGtGsllrallekl 18 G+G+G+++++ ++ tr|Q38BP3|Q38BP3_TRYB2 66 GGGNGNVSHRTDNEQ 80 999999999998874 PP == domain 2 score: 19.6 bits; conditional E-value: 2.5e-06 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvas 73 L++GcG G +++ +++ + +++vD s+ + +a+ +k++ nn ++++ d+ ++ + +fDv+++ tr|Q38BP3|Q38BP3_TRYB2 146 LHLGCGMGLVSMIAARS-LASAVVAVDRSAIVD-AAQVVAKKNGLNNISFFRGALVDVVQNFPVRQFDVIICE 216 789*****999988888.788888999988888.888888899999999999999999999999*******85 PP >> tr|Q4FKJ2|Q4FKJ2_TRYB2 Methyltransferase OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb10.6k1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.1 0.0 3.4 7.6e+02 41 72 .. 34 64 .. 11 68 .. 0.55 2 ! 18.6 0.0 4.9e-06 0.0011 1 98 [. 109 204 .. 109 205 .. 0.89 Alignments for each domain: == domain 1 score: -0.1 bits; conditional E-value: 3.4 Methyltransf_12 41 akrennnnnnvnlealdlldldgg......ssfDvvva 72 ++r + + + + + +++D+v+ tr|Q4FKJ2|Q4FKJ2_TRYB2 34 RDRYDGKGASASERRQ-------DatsltnEYYDIVTD 64 3333333333333333.......044444479999985 PP == domain 2 score: 18.6 bits; conditional E-value: 4.9e-06 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.ssfDvvvasnvlhhlkdireal 86 L++GcG G +r + + +++ gv ++ +i++a+++ ++++ ++n+ ++d + g + fD ++a+++ +h + + + tr|Q4FKJ2|Q4FKJ2_TRYB2 109 LDVGCGIGGPARNMVRF-TSCNVMGVNNNEYQINRARQHDSRYGMS--GKINYTKTDFCNMCFGdNEFDGAYAIEATCHSESKVKCY 192 8************9988.9**************9999999999864..477777777776666678********************* PP Methyltransf_12 87 dniyklLkpgGr 98 +++ +++kpg+ tr|Q4FKJ2|Q4FKJ2_TRYB2 193 SEVFRAIKPGAY 204 **********86 PP >> tr|Q389Z0|Q389Z0_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.6 0.1 5e-06 0.0011 1 72 [. 215 310 .. 215 316 .. 0.81 Alignments for each domain: == domain 1 score: 18.6 bits; conditional E-value: 5e-06 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg....................... 64 L+ cGtG + a++++ p +++t+vDi +ai a+e+ ak ++ ++++ + d++++ tr|Q389Z0|Q389Z0_TRYB2 215 LDMCCGTGCVGIAIAKHVPSAQVTAVDILDEAI-GASEENAKLNGLEASRFCTLKSDMFESFLVsnsgsltgedtkldlkkkepaae 300 7899*****************************.88888888888877777777777776666577777888887777777777777 PP Methyltransf_12 65 ..ssfDvvva 72 +sfD++v+ tr|Q389Z0|Q389Z0_TRYB2 301 haGSFDIIVS 310 7777777776 PP >> tr|Q585P9|Q585P9_TRYB2 rRNA adenine N(6)-methyltransferase OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX= # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.4 0.0 5.5e-06 0.0012 1 70 [. 93 157 .. 93 179 .. 0.78 Alignments for each domain: == domain 1 score: 18.4 bits; conditional E-value: 5.5e-06 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvv 70 LeiG GtG+l+++ll++ ++++ +++p++++ ++++ + ++++ + ld++ + +fD tr|Q585P9|Q585P9_TRYB2 93 LEIGPGTGNLTEKLLQA--AKKVIAFEVDPRMVAELNKRFQNSP--LAPKLQVIRGNCLDHEFP-YFDKC 157 8****************..**************55555555554..566777777777777776.66644 PP >> tr|Q38EH6|Q38EH6_TRYB2 Spermidine synthase, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.4 0.0 4.2 9.5e+02 49 80 .. 35 86 .. 25 93 .. 0.73 2 ! 16.5 0.0 2.2e-05 0.0049 1 72 [. 92 167 .. 92 170 .. 0.76 Alignments for each domain: == domain 1 score: -0.4 bits; conditional E-value: 4.2 Methyltransf_12 49 nnvnlealdlldldgg...............ssfDvvvasnvlhhl.....k 80 + ++++l+++++d++ fD v ++ l+h+ + tr|Q38EH6|Q38EH6_TRYB2 35 TPTKFQHLSIFETDPKgpwgtvmtldgciqlTDFDEFVYHEMLSHTplcahP 86 5667777888888888777788888888888888988999999888666554 PP == domain 2 score: 16.5 bits; conditional E-value: 2.2e-05 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg........ssfDvvva 72 L iG+G+G ++r++l++ + + vDi+ ++ie+ k+ + +++ + + +++ dg +sfDvv++ tr|Q38EH6|Q38EH6_TRYB2 92 LIIGGGDGGVMREVLRHGTVKRCVLVDIDGDVIEASKKYFPQISSGFS-DPRADVRVG---DGVafvreaasESFDVVII 167 569******************************999999999886544.333333332...2223346788999999986 PP >> tr|Q38BY6|Q38BY6_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.0 0.0 3.2e-05 0.0072 1 43 [. 315 356 .. 315 378 .. 0.87 Alignments for each domain: == domain 1 score: 16.0 bits; conditional E-value: 3.2e-05 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakr 43 L+ Gc +G +++ ll++ e++gvD+sp+ + +a++ l+++ tr|Q38BY6|Q38BY6_TRYB2 315 LDCGCHSGYMTELLLKA-GAQEVLGVDVSPHHLGNAEATLSEH 356 899**************.999999*********8888777765 PP >> tr|Q38E77|Q38E77_TRYB2 tRNA (guanine-N(7)-)-methyltransferase OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.1 0.0 2.9e-05 0.0066 1 45 [. 56 100 .. 56 111 .. 0.92 2 ? -1.6 0.0 10 2.2e+03 19 44 .. 184 209 .. 170 237 .. 0.58 Alignments for each domain: == domain 1 score: 16.1 bits; conditional E-value: 2.9e-05 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakren 45 +++Gc G +l+ l++++pd +g++i p+++e a++k k ++ tr|Q38E77|Q38E77_TRYB2 56 VDVGCAFGGMLFSLAPDFPDMCMLGLEIRPKVVEFAQNKVMKLRE 100 69************************************9988776 PP == domain 2 score: -1.6 bits; conditional E-value: 10 Methyltransf_12 19 pdieytgvDispsaiedakeklakre 44 +++ +t++D p + + +e+la +e tr|Q38E77|Q38E77_TRYB2 184 ERWMVTCLDGCPLFRQLSQEELAGNE 209 55666666655555544444444443 PP >> tr|Q57YX1|Q57YX1_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.6 0.0 2.1e-05 0.0048 2 53 .. 51 111 .. 50 169 .. 0.82 Alignments for each domain: == domain 1 score: 16.6 bits; conditional E-value: 2.1e-05 Methyltransf_12 2 eiGcGtGsllrallekl.........pdieytgvDispsaiedakeklakrennnnnnvnl 53 ++GcG+G+ l l+ +l ++ +gvDi++s i+da++ a+ ++ + +l tr|Q57YX1|Q57YX1_TRYB2 51 DLGCGDGAALLQLCCELfllqtkscpLHLIAVGVDIDESLITDARRAAADAVAKVPSPHQL 111 89******9999998889******87788888*********99999988877766555554 PP >> tr|Q57WE9|Q57WE9_TRYB2 Protein arginine methyltransferase NDUFAF7 OS=Trypanosoma brucei brucei (strain 927/4 GUTat10 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.2 0.0 2.8e-05 0.0064 2 42 .. 184 232 .. 183 258 .. 0.86 Alignments for each domain: == domain 1 score: 16.2 bits; conditional E-value: 2.8e-05 Methyltransf_12 2 eiGcGtGsllrallekl........pdieytgvDispsaiedakeklak 42 +iG+G+G+l+ +l++l +++ey++v+i+p+ ++ +++l tr|Q57WE9|Q57WE9_TRYB2 184 DIGAGSGALAVSVLDYLsehfpsvyEQCEYHVVEINPQLVQVLRNRLIM 232 9***************************************777777654 PP >> tr|Q582P2|Q582P2_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.8 0.0 7.4e-05 0.017 1 98 [. 550 671 .. 550 672 .. 0.92 Alignments for each domain: == domain 1 score: 14.8 bits; conditional E-value: 7.4e-05 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg....................... 64 L++ cG G+++++l +++g+D+s++ + + +++r+ + + vn + ++ + tr|Q582P2|Q582P2_TRYB2 550 LDFACGAGRIAFELTSM--FDQVVGSDFSARLL-IPAYAISERGSYTYSIVNSSTSRRVEQTFKslgypwdatrgravffqadptnl 633 8****************..**************.8888999999999899988888888888888999******************* PP Methyltransf_12 65 ....ssfDvvvasnvlhhlkdirealdniyklLkpgGr 98 + f ++++ n+l ++ ++ +++ + L+ gG tr|Q582P2|Q582P2_TRYB2 634 hshmKDFSLILCWNTLDRSYNPTAVPSHMVDRLVVGGL 671 **999***********9999999999999999999986 PP >> tr|Q4GYR8|Q4GYR8_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=TB # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.2 0.0 5.5e-05 0.012 1 56 [. 401 454 .. 401 475 .. 0.88 Alignments for each domain: == domain 1 score: 15.2 bits; conditional E-value: 5.5e-05 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnleal 56 L++ cGtG++ al+++ +++g+++ +sa+ da++ +++ +n++++ +++ tr|Q4GYR8|Q4GYR8_TRYB2 401 LDLCCGTGTIGIALAKH--VKRVIGIELVESAVRDARLNAERNGVRNATFNCGRVE 454 899**************..**************99999999999888877665555 PP >> tr|Q4GZF2|Q4GZF2_TRYB2 Histone-lysine N-methyltransferase, H3 lysine-79 specific OS=Trypanosoma brucei brucei (strai # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.0 0.0 6.7e-05 0.015 2 39 .. 117 153 .. 116 187 .. 0.86 Alignments for each domain: == domain 1 score: 15.0 bits; conditional E-value: 6.7e-05 Methyltransf_12 2 eiGcGtGsllralleklpdieytgvDispsaiedakek 39 ++GcG+Gs+l++++ + +++ +gv+i+++ + ake tr|Q4GZF2|Q4GZF2_TRYB2 117 DLGCGNGSVLFHVALA-TGASCVGVEINEHNAKVAKEA 153 89***********999.999999*******99777775 PP >> tr|Q389B6|Q389B6_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.5 0.0 9.5e-05 0.021 1 78 [. 114 189 .. 114 205 .. 0.80 Alignments for each domain: == domain 1 score: 14.5 bits; conditional E-value: 9.5e-05 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg..ssfDvvvasnvlhh 78 L+iG+G+G+ + l+ + +++++g++ ++ i + ++ +r+++ +v + + d+ + + +s+D+v+++ +lh tr|Q389B6|Q389B6_TRYB2 114 LDIGSGSGRDMVFLASR--GWHVVGIENRRRLI--WQGETLARKHDVSGRVAYLHSDIKEAYPVrsGSVDLVHVCRFLHR 189 8**************99..**************..44444455555667888888887666555899***********96 PP >> tr|Q581Z0|Q581Z0_TRYB2 Histone-lysine N-methyltransferase, H3 lysine-79 specific OS=Trypanosoma brucei brucei (strai # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.4 0.0 0.0001 0.023 2 38 .. 134 169 .. 133 178 .. 0.88 Alignments for each domain: == domain 1 score: 14.4 bits; conditional E-value: 0.0001 Methyltransf_12 2 eiGcGtGsllralleklpdieytgvDispsaiedake 38 ++GcG+Gs+l+ ++ +++ +g++is++ + ak+ tr|Q581Z0|Q581Z0_TRYB2 134 DLGCGNGSILFQVAFL-TGARCVGIEISEHNAKVAKK 169 89***********998.9************9966665 PP >> tr|Q38BN0|Q38BN0_TRYB2 rRNA adenine N(6)-methyltransferase OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX= # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.0 0.0 0.00013 0.03 1 61 [. 99 157 .. 99 179 .. 0.90 Alignments for each domain: == domain 1 score: 14.0 bits; conditional E-value: 0.00013 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldl 61 Le+G G G+l+r ll + p + ++g++ ++++ + e+++++ n ++++ n ++l + +l tr|Q38BN0|Q38BN0_TRYB2 99 LELGPGAGALTRSLLTR-PCVGVLGIEQDERFN-GHLEQIRQYTNGKFQWTNGDVLRINEL 157 8****************.***************.999999999999999999888887655 PP >> sp|Q582G4|ANM7_TRYB2 Protein arginine N-methyltransferase 7 OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.7 0.0 0.00034 0.078 1 71 [. 100 188 .. 100 199 .. 0.69 2 ? -1.4 0.0 8.2 1.9e+03 52 71 .. 272 291 .. 254 311 .. 0.60 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 0.00034 Methyltransf_12 1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvnlealdlldldgg.....................ssfD 68 LeiG+G+G l+ + ++ +++v+ s++ + a+e +++++ ++ +v++ + +l+++ s+ D sp|Q582G4|ANM7_TRYB2 100 LEIGAGSGLLSLMAAKL-GAKWVVAVEGSEELAKLARENIRANNMEH--QVKVLHMMSTELKSKhlpeppdvllseifgtmmlgeSALD 185 8*******888888877.666666*********88888888777544..5555444444444446666666666655555555555555 PP Methyltransf_12 69 vvv 71 +vv sp|Q582G4|ANM7_TRYB2 186 YVV 188 555 PP == domain 2 score: -1.4 bits; conditional E-value: 8.2 Methyltransf_12 52 nlealdlldldggssfDvvv 71 ++ + d + +++fDvv sp|Q582G4|ANM7_TRYB2 272 DFSSSNRNDIPRRKHFDVVA 291 33333333333337888885 PP >> tr|Q381Q6|Q381Q6_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.8 0.1 0.00016 0.035 1 35 [. 58 108 .. 58 166 .. 0.87 Alignments for each domain: == domain 1 score: 13.8 bits; conditional E-value: 0.00016 Methyltransf_12 1 LeiGcGtGsllrallekl................pdieytgvDispsaied 35 +eiGcG+G+++++l l +++e+++vD++p a+e+ tr|Q381Q6|Q381Q6_TRYB2 58 VEIGCGSGTVISHLMLLLlgateggnlgsgsaekSTAEFHAVDVNPVALEA 108 69************99999**************99************9944 PP >> tr|Q383B4|Q383B4_TRYB2 tRNA (adenine(58)-N(1))-methyltransferase OS=Trypanosoma brucei brucei (strain 927/4 GUTat10. # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.2 0.0 0.0084 1.9 2 44 .. 170 213 .. 169 232 .. 0.89 2 ? 4.1 0.0 0.16 37 79 99 .] 277 297 .. 241 297 .. 0.80 Alignments for each domain: == domain 1 score: 8.2 bits; conditional E-value: 0.0084 Methyltransf_12 2 eiGcGtGsllrallekl.pdieytgvDispsaiedakeklakre 44 e G+G+Gsl++ l++ pd ++ +D++++ + a +++++++ tr|Q383B4|Q383B4_TRYB2 170 EAGTGSGSLTHSLARTVaPDGIVYTYDFHKKRCLEALQEFRRNG 213 78**************99999999*******9989988888775 PP == domain 2 score: 4.1 bits; conditional E-value: 0.16 Methyltransf_12 79 lkdirealdniyklLkpgGrl 99 ++ + a+dn+ ++L+pgG+l tr|Q383B4|Q383B4_TRYB2 277 VPSPWLAIDNVLHVLRPGGML 297 366677999**********87 PP >> tr|Q385R2|Q385R2_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.7 0.0 0.92 2.1e+02 1 16 [. 288 303 .. 288 354 .. 0.86 2 ? 8.5 0.0 0.0071 1.6 19 94 .. 475 548 .. 462 549 .. 0.80 Alignments for each domain: == domain 1 score: 1.7 bits; conditional E-value: 0.92 Methyltransf_12 1 LeiGcGtGsllralle 16 L++G+GtG+ + + e tr|Q385R2|Q385R2_TRYB2 288 LDFGAGTGTAILVAKE 303 8*******98877665 PP == domain 2 score: 8.5 bits; conditional E-value: 0.0071 Methyltransf_12 19 pdieytgvDispsaiedakeklakrennnnnnvnlealdlldldggssfDvvvasnvlhhl...kdirealdniyklLk 94 p e+t+v++sp ++e l++ + nv+++ l +++ + D+vva+ l+ + +++r++++++ k+ k tr|Q385R2|Q385R2_TRYB2 475 PLQEVTAVEPSPGMMEIGTMVLHDDVP----NVTWKRYLLPEDEAI-QHDLVVAAYSLSEIatsENRRRIVQQLWKMTK 548 558999*********776666666665....777777777766665.9*************9***********999865 PP >> tr|Q38AH9|Q38AH9_TRYB2 Protein-L-isoaspartate, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.1 0.0012 0.26 1 73 [. 93 174 .. 93 194 .. 0.57 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 0.0012 Methyltransf_12 1 LeiGcGtGsllrallekl..pdieytgvD.ispsai...edakeklakrennnnnnvnlealdlldldgg..........ssfDvvv 71 L++G+G+G l+++l+e ++ +++gv+ is+ ++ e ++++ ++v+ ++ ++ dg+ fDv++ tr|Q38AH9|Q38AH9_TRYB2 93 LDVGSGSGYLTAVLAELCsgRGGTVIGVEhISELVVrstEV-------VNKHFRSWVEEGRIKFIEGDGRnitgllgqkvPDFDVIH 172 8***************9999888888886255555533222.......222233455555555555555544444444666666664 PP Methyltransf_12 72 as 73 + tr|Q38AH9|Q38AH9_TRYB2 173 VG 174 43 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (99 nodes) Target sequences: 8561 (4332363 residues searched) Passed MSV filter: 360 (0.0420512); expected 171.2 (0.02) Passed bias filter: 346 (0.0404158); expected 171.2 (0.02) Passed Vit filter: 75 (0.00876066); expected 8.6 (0.001) Passed Fwd filter: 38 (0.00443873); expected 0.1 (1e-05) Initial search space (Z): 8561 [actual number of targets] Domain search space (domZ): 38 [number of targets reported over threshold] # CPU time: 0.11u 0.00s 00:00:00.11 Elapsed: 00:00:00.04 # Mc/sec: 10722.60 // [ok]