# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/Methyltransf_15.hmm.txt # target sequence database: proteomes/Ciona_intestinalis.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: Methyltransf_15 [M=165] Accession: PF09445.9 Description: RNA cap guanine-N2 methyltransferase Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7e-38 129.8 0.1 1e-37 129.3 0.1 1.2 1 tr|F6PXD8|F6PXD8_CIOIN Uncharacterized protein OS=Ciona inte 1.1e-07 31.6 0.1 1.9e-07 30.9 0.1 1.4 1 tr|F6WB92|F6WB92_CIOIN methyltransferase-like protein 5 isof 7.7e-05 22.4 0.0 0.00014 21.5 0.0 1.4 1 tr|H2XKR4|H2XKR4_CIOIN Uncharacterized protein OS=Ciona inte 0.00029 20.5 0.0 0.00054 19.6 0.0 1.4 1 tr|F7B763|F7B763_CIOIN Uncharacterized protein OS=Ciona inte 0.00034 20.3 0.0 0.00059 19.5 0.0 1.4 1 tr|H2XQ96|H2XQ96_CIOIN Uncharacterized protein OS=Ciona inte 0.00034 20.3 0.0 0.00056 19.5 0.0 1.3 1 tr|H2XVH5|H2XVH5_CIOIN Uncharacterized protein OS=Ciona inte 0.00035 20.2 0.0 0.00069 19.3 0.0 1.5 1 tr|F7B757|F7B757_CIOIN Uncharacterized protein OS=Ciona inte 0.0004 20.0 0.0 0.00063 19.4 0.0 1.3 1 tr|H2XNZ2|H2XNZ2_CIOIN Uncharacterized protein OS=Ciona inte 0.0012 18.5 0.0 0.002 17.7 0.0 1.4 1 tr|H2Y1L1|H2Y1L1_CIOIN Uncharacterized protein OS=Ciona inte 0.0014 18.3 0.0 0.0026 17.4 0.0 1.6 1 tr|F6ZXR3|F6ZXR3_CIOIN Uncharacterized protein OS=Ciona inte 0.0014 18.3 0.1 0.0032 17.1 0.0 1.7 2 tr|H2XS49|H2XS49_CIOIN Uncharacterized protein OS=Ciona inte ------ inclusion threshold ------ 0.011 15.4 0.0 0.022 14.4 0.0 1.5 2 tr|H2Y3J5|H2Y3J5_CIOIN Uncharacterized protein OS=Ciona inte 0.029 14.0 0.1 0.078 12.6 0.0 1.7 2 tr|F6RBS2|F6RBS2_CIOIN Uncharacterized protein OS=Ciona inte 0.033 13.8 1.5 0.17 11.5 0.1 2.8 3 tr|F6UUI8|F6UUI8_CIOIN Uncharacterized protein OS=Ciona inte 0.033 13.8 0.0 0.048 13.3 0.0 1.3 1 tr|F6QVW6|F6QVW6_CIOIN Uncharacterized protein OS=Ciona inte 0.057 13.0 0.0 0.12 12.0 0.0 1.5 1 sp|F7A355|TRM5_CIOIN tRNA (guanine(37)-N1)-methyltransfera 0.06 12.9 0.0 0.11 12.1 0.0 1.5 1 tr|I6L7H7|I6L7H7_CIOIN tRNA (guanine(37)-N1)-methyltransfera Domain annotation for each sequence (and alignments): >> tr|F6PXD8|F6PXD8_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 PE=4 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 129.3 0.1 1e-40 1e-37 2 164 .. 83 234 .. 82 235 .. 0.92 Alignments for each domain: == domain 1 score: 129.3 bits; conditional E-value: 1e-40 Methyltransf_15 2 evvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfellaklkleeikvdlvflSpPwGGpsYkk 88 v++D+f+G+GGn+iqfa + ekv aidi++ +l+ a+hNa +Ygv+d++++++g +f++ +l k d+vflSpPwGGp+Y++ tr|F6PXD8|F6PXD8_CIOIN 83 DVIVDAFCGSGGNAIQFAFTCEKVLAIDIDPVKLENAKHNAAIYGVEDRIDFICGSFFDIAPTL-----KADIVFLSPPWGGPEYTN 164 689********************************************************98774.....4589************** PP Methyltransf_15 89 kekfdlekkleplklekllkesvklskniilfLPrnsdlkqlaaltaevlenaskvkvvklkenglvkallaylge 164 e++++ ++ ++ k + + ++s+ni +fLPrns++++l l +++ ++v++ + n+ + +++ay+g+ tr|F6PXD8|F6PXD8_CIOIN 165 CETYSI-AEMGDFGT-KAFTLAKNISDNIAFFLPRNSNVDELVCL----AGPGNQVELEQNMLNNKIVTITAYYGK 234 ******.99999976.6678899*******************876....799999999999999999999999886 PP >> tr|F6WB92|F6WB92_CIOIN methyltransferase-like protein 5 isoform X4 OS=Ciona intestinalis OX=7719 GN=LOC100184601 PE= # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.9 0.1 1.9e-10 1.9e-07 4 87 .. 52 137 .. 49 172 .. 0.76 Alignments for each domain: == domain 1 score: 30.9 bits; conditional E-value: 1.9e-10 Methyltransf_15 4 vlDlfgGaGGnviqfanv.fekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfe..llaklkleeikvdlvflSpPwGGpsYk 87 v Dl +G+G +i + ++ +idi+++ l++ q N+e+Y+ ++ v+++++d+ +++ l++ ++d v++ pP G s k tr|F6WB92|F6WB92_CIOIN 52 VCDLGCGCGILSIGSSLLgANHCLGIDIDEDALEIFQSNCEAYELNNVVECIQADIARfsPSRNMILAK-RFDTVLMNPPFGTKSNK 137 679999999999999988556799*******************************98832334444444.48**********87655 PP >> tr|H2XKR4|H2XKR4_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.5 0.0 1.4e-07 0.00014 3 43 .. 48 88 .. 46 107 .. 0.88 Alignments for each domain: == domain 1 score: 21.5 bits; conditional E-value: 1.4e-07 Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNae 43 +lD+ +G+G ++ fa +f++v aid+++++lk a+ + tr|H2XKR4|H2XKR4_CIOIN 48 FLLDVGCGGGQTTNIFAPYFHEVLAIDVSENQLKEAKSQNK 88 68********************************9986555 PP >> tr|F7B763|F7B763_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 PE=4 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.6 0.0 5.5e-07 0.00054 3 45 .. 41 83 .. 39 110 .. 0.88 Alignments for each domain: == domain 1 score: 19.6 bits; conditional E-value: 5.5e-07 Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevY 45 +lD+ +G+G v+ fa +f++v aid ++++lk a ++ tr|F7B763|F7B763_CIOIN 41 FLLDVGCGGGQSVNIFAPYFHEVLAIDPSENQLKEARSQNKFA 83 68********************************998776665 PP >> tr|H2XQ96|H2XQ96_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.5 0.0 6e-07 0.00059 3 52 .. 6 51 .. 4 75 .. 0.85 Alignments for each domain: == domain 1 score: 19.5 bits; conditional E-value: 6e-07 Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvt 52 +lD+ +G+G v+ fa +f++v aid ++++lk a ++ +vt tr|H2XQ96|H2XQ96_CIOIN 6 FLLDVGCGGGQSVNIFAPYFNQVLAIDPSENQLKEARSQNQFA----HVT 51 689*******************************998777665....444 PP >> tr|H2XVH5|H2XVH5_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.5 0.0 5.7e-07 0.00056 3 45 .. 7 49 .. 5 64 .. 0.88 Alignments for each domain: == domain 1 score: 19.5 bits; conditional E-value: 5.7e-07 Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevY 45 +lD+ +G+G v+ fa +f++v aid +++++k a ++ tr|H2XVH5|H2XVH5_CIOIN 7 FLLDVGCGGGQSVNIFAPYFHEVLAIDPSENQIKEARSQNKFA 49 689*******************************998776665 PP >> tr|F7B757|F7B757_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 PE=4 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.3 0.0 7e-07 0.00069 3 45 .. 41 83 .. 39 106 .. 0.88 Alignments for each domain: == domain 1 score: 19.3 bits; conditional E-value: 7e-07 Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevY 45 +lD+ +G+G v+ fa +f++v aid +++++k a ++ tr|F7B757|F7B757_CIOIN 41 FLLDVGCGGGQSVNIFAPYFHEVLAIDPSENQIKEARSQNKFA 83 689*******************************998766665 PP >> tr|H2XNZ2|H2XNZ2_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.4 0.0 6.5e-07 0.00063 3 54 .. 44 91 .. 42 120 .. 0.86 Alignments for each domain: == domain 1 score: 19.4 bits; conditional E-value: 6.5e-07 Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvtlv 54 +lD+ +GaG + f +f++v ++d +l +l+ a++N+ + +vt++ tr|H2XNZ2|H2XNZ2_CIOIN 44 FLLDVSCGAGQATKLFSPYFKTVLGVDPSLPQLETAKENCYFD----NVTFK 91 68*************************************9765....55554 PP >> tr|H2Y1L1|H2Y1L1_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.7 0.0 2.1e-06 0.002 3 45 .. 43 85 .. 41 111 .. 0.90 Alignments for each domain: == domain 1 score: 17.7 bits; conditional E-value: 2.1e-06 Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevY 45 +lD+ +GaG + f +f++v ++d +l++l+ a++N+ + tr|H2Y1L1|H2Y1L1_CIOIN 43 FLLDVGCGAGQATKLFCPYFKTVLGVDPSLKQLETAKENCCFD 85 689*************************************764 PP >> tr|F6ZXR3|F6ZXR3_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 PE=4 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.4 0.0 2.7e-06 0.0026 6 57 .. 3 50 .. 1 90 [. 0.84 Alignments for each domain: == domain 1 score: 17.4 bits; conditional E-value: 2.7e-06 Methyltransf_15 6 DlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvtlvlgd 57 + +G+G + +f +f+++i+idi+ ++++ a++N + +v + +gd tr|F6ZXR3|F6ZXR3_CIOIN 3 EVGCGSGQAIKKFVSYFDNIIGIDISAEQIQEAEQNNPFP----NVSYAVGD 50 677999999999************************9887....44455555 PP >> tr|H2XS49|H2XS49_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.1 0.0 3.3e-06 0.0032 3 48 .. 45 90 .. 43 111 .. 0.87 2 ? -2.8 0.0 4.2 4.1e+03 35 46 .. 140 151 .. 122 172 .. 0.70 Alignments for each domain: == domain 1 score: 17.1 bits; conditional E-value: 3.3e-06 Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvs 48 +lD+ +G+G v fa +f+kv aid ++++l+ a ++ v tr|H2XS49|H2XS49_CIOIN 45 FLLDVGCGGGQAVKIFAPYFDKVLAIDPSENQLEEARSQNKFAHVT 90 689******99999*******************9988777765554 PP == domain 2 score: -2.8 bits; conditional E-value: 4.2 Methyltransf_15 35 lklaqhNaevYg 46 l+++++ a++Y+ tr|H2XS49|H2XS49_CIOIN 140 LQVCNKYAQIYN 151 555666666663 PP >> tr|H2Y3J5|H2Y3J5_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.4 0.0 2.2e-05 0.022 3 38 .. 42 77 .. 40 96 .. 0.91 2 ? -3.5 0.1 6.9 6.8e+03 25 40 .. 145 160 .. 142 172 .. 0.51 Alignments for each domain: == domain 1 score: 14.4 bits; conditional E-value: 2.2e-05 Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrlkla 38 ++lD+ +GaG ++ fa + + v aid ++++lk a tr|H2Y3J5|H2Y3J5_CIOIN 42 YLLDVGCGAGRSANVFAPYSHDVLAIDPSENELKEA 77 79*****************************99976 PP == domain 2 score: -3.5 bits; conditional E-value: 6.9 Methyltransf_15 25 viaidinlsrlklaqh 40 v++++inl+ + q+ tr|H2Y3J5|H2Y3J5_CIOIN 145 VYCLEINLTYFFINQK 160 5555555554444333 PP >> tr|F6RBS2|F6RBS2_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 PE=4 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 0.0 7.9e-05 0.078 5 47 .. 46 88 .. 43 117 .. 0.81 2 ? -1.8 0.0 2.1 2e+03 23 23 .. 219 219 .. 166 262 .. 0.63 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 7.9e-05 Methyltransf_15 5 lDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgv 47 +D+ +G+G ++ fa +f+kv a d + ++l+ a ++ +v tr|F6RBS2|F6RBS2_CIOIN 46 VDVGCGSGQATNIFAPYFKKVLATDPSVNQLEHARMQNKFDNV 88 89****************************9988776666544 PP == domain 2 score: -1.8 bits; conditional E-value: 2.1 Methyltransf_15 23 e 23 + tr|F6RBS2|F6RBS2_CIOIN 219 R 219 1 PP >> tr|F6UUI8|F6UUI8_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 GN=LOC100182889 PE=3 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.1 0.0 1.3 1.3e+03 119 154 .. 48 84 .. 15 89 .. 0.73 2 ? -1.3 0.0 1.5 1.5e+03 60 87 .. 199 232 .. 125 253 .. 0.54 3 ? 11.5 0.1 0.00017 0.17 3 60 .. 429 485 .. 427 538 .. 0.81 Alignments for each domain: == domain 1 score: -1.1 bits; conditional E-value: 1.3 Methyltransf_15 119 lfLPrnsdlkqlaalt.aevlenaskvkvvklkengl 154 LPr +l++l+ +++ n +k++vv+ ++ + tr|F6UUI8|F6UUI8_CIOIN 48 GNLPRHCGYGELKKLMnKKLKLNPHKINVVSRINKAY 84 4699999999998865267888999999988777666 PP == domain 2 score: -1.3 bits; conditional E-value: 1.5 Methyltransf_15 60 e.....llaklkleei...kvdlvflSpPwGGpsYk 87 + l + k+e+ +d ++ Sp +GG Y+ tr|F6UUI8|F6UUI8_CIOIN 199 DnevfvWLMQQKKESGafcPMDDILPSPCVGG--YR 232 02233322222222211235566666666666..55 PP == domain 3 score: 11.5 bits; conditional E-value: 0.00017 Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfe 60 +lD+++G+G ++ ++ +++di ++ + a +Na + ++ + ++ +g+ ++ tr|F6UUI8|F6UUI8_CIOIN 429 ALLDVCCGTGTIGLTLSSCVNRLVGVDICEQAIIDAVKNATLNNITNA-EFYVGKAED 485 68********99999*************************99987653.445555555 PP >> tr|F6QVW6|F6QVW6_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 PE=3 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 0.0 4.9e-05 0.048 3 64 .. 20 81 .. 18 132 .. 0.84 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 4.9e-05 Methyltransf_15 3 vvlDlfgGaGGnviqfanv..fekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfellak 64 v++D+ GaGG + + + ++kvia+d +++ ++aq + + + ++ lg++ el + tr|F6QVW6|F6QVW6_CIOIN 20 VIIDMTFGAGGHTKFIMENykHCKVIALDRDEKAFEIAQDLSKKF--KGRIIPLLGKFSELDKL 81 79*********9975544425789****************99999..99999999999885443 PP >> sp|F7A355|TRM5_CIOIN tRNA (guanine(37)-N1)-methyltransferase OS=Ciona intestinalis OX=7719 PE=3 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 0.0 0.00012 0.12 3 46 .. 258 301 .. 256 339 .. 0.87 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 0.00012 Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYg 46 vv D+f+G G +i +a+ + v+a d n++ + hN + sp|F7A355|TRM5_CIOIN 258 VVFDVFAGVGPFAIPIAKKGCVVYANDLNPESYRWLLHNVALNK 301 789************************************98764 PP >> tr|I6L7H7|I6L7H7_CIOIN tRNA (guanine(37)-N1)-methyltransferase OS=Ciona intestinalis OX=7719 PE=3 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.0 0.00011 0.11 3 47 .. 277 321 .. 275 383 .. 0.87 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 0.00011 Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgv 47 vv D+f+G G +i +a+ + v+a d n++ + hN + tr|I6L7H7|I6L7H7_CIOIN 277 VVFDVFAGVGPFAIPIAKKGCVVYANDLNPESYRWLLHNVALNKT 321 789************************************987644 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (165 nodes) Target sequences: 16678 (5370518 residues searched) Passed MSV filter: 605 (0.0362753); expected 333.6 (0.02) Passed bias filter: 438 (0.0262621); expected 333.6 (0.02) Passed Vit filter: 51 (0.00305792); expected 16.7 (0.001) Passed Fwd filter: 17 (0.00101931); expected 0.2 (1e-05) Initial search space (Z): 16678 [actual number of targets] Domain search space (domZ): 17 [number of targets reported over threshold] # CPU time: 0.10u 0.00s 00:00:00.10 Elapsed: 00:00:00.04 # Mc/sec: 22153.39 // [ok]