# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/Methyltransf_15.hmm.txt
# target sequence database: proteomes/Ciona_intestinalis.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: Methyltransf_15 [M=165]
Accession: PF09445.9
Description: RNA cap guanine-N2 methyltransferase
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
7e-38 129.8 0.1 1e-37 129.3 0.1 1.2 1 tr|F6PXD8|F6PXD8_CIOIN Uncharacterized protein OS=Ciona inte
1.1e-07 31.6 0.1 1.9e-07 30.9 0.1 1.4 1 tr|F6WB92|F6WB92_CIOIN methyltransferase-like protein 5 isof
7.7e-05 22.4 0.0 0.00014 21.5 0.0 1.4 1 tr|H2XKR4|H2XKR4_CIOIN Uncharacterized protein OS=Ciona inte
0.00029 20.5 0.0 0.00054 19.6 0.0 1.4 1 tr|F7B763|F7B763_CIOIN Uncharacterized protein OS=Ciona inte
0.00034 20.3 0.0 0.00059 19.5 0.0 1.4 1 tr|H2XQ96|H2XQ96_CIOIN Uncharacterized protein OS=Ciona inte
0.00034 20.3 0.0 0.00056 19.5 0.0 1.3 1 tr|H2XVH5|H2XVH5_CIOIN Uncharacterized protein OS=Ciona inte
0.00035 20.2 0.0 0.00069 19.3 0.0 1.5 1 tr|F7B757|F7B757_CIOIN Uncharacterized protein OS=Ciona inte
0.0004 20.0 0.0 0.00063 19.4 0.0 1.3 1 tr|H2XNZ2|H2XNZ2_CIOIN Uncharacterized protein OS=Ciona inte
0.0012 18.5 0.0 0.002 17.7 0.0 1.4 1 tr|H2Y1L1|H2Y1L1_CIOIN Uncharacterized protein OS=Ciona inte
0.0014 18.3 0.0 0.0026 17.4 0.0 1.6 1 tr|F6ZXR3|F6ZXR3_CIOIN Uncharacterized protein OS=Ciona inte
0.0014 18.3 0.1 0.0032 17.1 0.0 1.7 2 tr|H2XS49|H2XS49_CIOIN Uncharacterized protein OS=Ciona inte
------ inclusion threshold ------
0.011 15.4 0.0 0.022 14.4 0.0 1.5 2 tr|H2Y3J5|H2Y3J5_CIOIN Uncharacterized protein OS=Ciona inte
0.029 14.0 0.1 0.078 12.6 0.0 1.7 2 tr|F6RBS2|F6RBS2_CIOIN Uncharacterized protein OS=Ciona inte
0.033 13.8 1.5 0.17 11.5 0.1 2.8 3 tr|F6UUI8|F6UUI8_CIOIN Uncharacterized protein OS=Ciona inte
0.033 13.8 0.0 0.048 13.3 0.0 1.3 1 tr|F6QVW6|F6QVW6_CIOIN Uncharacterized protein OS=Ciona inte
0.057 13.0 0.0 0.12 12.0 0.0 1.5 1 sp|F7A355|TRM5_CIOIN tRNA (guanine(37)-N1)-methyltransfera
0.06 12.9 0.0 0.11 12.1 0.0 1.5 1 tr|I6L7H7|I6L7H7_CIOIN tRNA (guanine(37)-N1)-methyltransfera
Domain annotation for each sequence (and alignments):
>> tr|F6PXD8|F6PXD8_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 PE=4 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 129.3 0.1 1e-40 1e-37 2 164 .. 83 234 .. 82 235 .. 0.92
Alignments for each domain:
== domain 1 score: 129.3 bits; conditional E-value: 1e-40
Methyltransf_15 2 evvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfellaklkleeikvdlvflSpPwGGpsYkk 88
v++D+f+G+GGn+iqfa + ekv aidi++ +l+ a+hNa +Ygv+d++++++g +f++ +l k d+vflSpPwGGp+Y++
tr|F6PXD8|F6PXD8_CIOIN 83 DVIVDAFCGSGGNAIQFAFTCEKVLAIDIDPVKLENAKHNAAIYGVEDRIDFICGSFFDIAPTL-----KADIVFLSPPWGGPEYTN 164
689********************************************************98774.....4589************** PP
Methyltransf_15 89 kekfdlekkleplklekllkesvklskniilfLPrnsdlkqlaaltaevlenaskvkvvklkenglvkallaylge 164
e++++ ++ ++ k + + ++s+ni +fLPrns++++l l +++ ++v++ + n+ + +++ay+g+
tr|F6PXD8|F6PXD8_CIOIN 165 CETYSI-AEMGDFGT-KAFTLAKNISDNIAFFLPRNSNVDELVCL----AGPGNQVELEQNMLNNKIVTITAYYGK 234
******.99999976.6678899*******************876....799999999999999999999999886 PP
>> tr|F6WB92|F6WB92_CIOIN methyltransferase-like protein 5 isoform X4 OS=Ciona intestinalis OX=7719 GN=LOC100184601 PE=
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 30.9 0.1 1.9e-10 1.9e-07 4 87 .. 52 137 .. 49 172 .. 0.76
Alignments for each domain:
== domain 1 score: 30.9 bits; conditional E-value: 1.9e-10
Methyltransf_15 4 vlDlfgGaGGnviqfanv.fekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfe..llaklkleeikvdlvflSpPwGGpsYk 87
v Dl +G+G +i + ++ +idi+++ l++ q N+e+Y+ ++ v+++++d+ +++ l++ ++d v++ pP G s k
tr|F6WB92|F6WB92_CIOIN 52 VCDLGCGCGILSIGSSLLgANHCLGIDIDEDALEIFQSNCEAYELNNVVECIQADIARfsPSRNMILAK-RFDTVLMNPPFGTKSNK 137
679999999999999988556799*******************************98832334444444.48**********87655 PP
>> tr|H2XKR4|H2XKR4_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 21.5 0.0 1.4e-07 0.00014 3 43 .. 48 88 .. 46 107 .. 0.88
Alignments for each domain:
== domain 1 score: 21.5 bits; conditional E-value: 1.4e-07
Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNae 43
+lD+ +G+G ++ fa +f++v aid+++++lk a+ +
tr|H2XKR4|H2XKR4_CIOIN 48 FLLDVGCGGGQTTNIFAPYFHEVLAIDVSENQLKEAKSQNK 88
68********************************9986555 PP
>> tr|F7B763|F7B763_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 PE=4 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 19.6 0.0 5.5e-07 0.00054 3 45 .. 41 83 .. 39 110 .. 0.88
Alignments for each domain:
== domain 1 score: 19.6 bits; conditional E-value: 5.5e-07
Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevY 45
+lD+ +G+G v+ fa +f++v aid ++++lk a ++
tr|F7B763|F7B763_CIOIN 41 FLLDVGCGGGQSVNIFAPYFHEVLAIDPSENQLKEARSQNKFA 83
68********************************998776665 PP
>> tr|H2XQ96|H2XQ96_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 19.5 0.0 6e-07 0.00059 3 52 .. 6 51 .. 4 75 .. 0.85
Alignments for each domain:
== domain 1 score: 19.5 bits; conditional E-value: 6e-07
Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvt 52
+lD+ +G+G v+ fa +f++v aid ++++lk a ++ +vt
tr|H2XQ96|H2XQ96_CIOIN 6 FLLDVGCGGGQSVNIFAPYFNQVLAIDPSENQLKEARSQNQFA----HVT 51
689*******************************998777665....444 PP
>> tr|H2XVH5|H2XVH5_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 19.5 0.0 5.7e-07 0.00056 3 45 .. 7 49 .. 5 64 .. 0.88
Alignments for each domain:
== domain 1 score: 19.5 bits; conditional E-value: 5.7e-07
Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevY 45
+lD+ +G+G v+ fa +f++v aid +++++k a ++
tr|H2XVH5|H2XVH5_CIOIN 7 FLLDVGCGGGQSVNIFAPYFHEVLAIDPSENQIKEARSQNKFA 49
689*******************************998776665 PP
>> tr|F7B757|F7B757_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 PE=4 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 19.3 0.0 7e-07 0.00069 3 45 .. 41 83 .. 39 106 .. 0.88
Alignments for each domain:
== domain 1 score: 19.3 bits; conditional E-value: 7e-07
Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevY 45
+lD+ +G+G v+ fa +f++v aid +++++k a ++
tr|F7B757|F7B757_CIOIN 41 FLLDVGCGGGQSVNIFAPYFHEVLAIDPSENQIKEARSQNKFA 83
689*******************************998766665 PP
>> tr|H2XNZ2|H2XNZ2_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 19.4 0.0 6.5e-07 0.00063 3 54 .. 44 91 .. 42 120 .. 0.86
Alignments for each domain:
== domain 1 score: 19.4 bits; conditional E-value: 6.5e-07
Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvtlv 54
+lD+ +GaG + f +f++v ++d +l +l+ a++N+ + +vt++
tr|H2XNZ2|H2XNZ2_CIOIN 44 FLLDVSCGAGQATKLFSPYFKTVLGVDPSLPQLETAKENCYFD----NVTFK 91
68*************************************9765....55554 PP
>> tr|H2Y1L1|H2Y1L1_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 17.7 0.0 2.1e-06 0.002 3 45 .. 43 85 .. 41 111 .. 0.90
Alignments for each domain:
== domain 1 score: 17.7 bits; conditional E-value: 2.1e-06
Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevY 45
+lD+ +GaG + f +f++v ++d +l++l+ a++N+ +
tr|H2Y1L1|H2Y1L1_CIOIN 43 FLLDVGCGAGQATKLFCPYFKTVLGVDPSLKQLETAKENCCFD 85
689*************************************764 PP
>> tr|F6ZXR3|F6ZXR3_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 PE=4 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 17.4 0.0 2.7e-06 0.0026 6 57 .. 3 50 .. 1 90 [. 0.84
Alignments for each domain:
== domain 1 score: 17.4 bits; conditional E-value: 2.7e-06
Methyltransf_15 6 DlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvtlvlgd 57
+ +G+G + +f +f+++i+idi+ ++++ a++N + +v + +gd
tr|F6ZXR3|F6ZXR3_CIOIN 3 EVGCGSGQAIKKFVSYFDNIIGIDISAEQIQEAEQNNPFP----NVSYAVGD 50
677999999999************************9887....44455555 PP
>> tr|H2XS49|H2XS49_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 17.1 0.0 3.3e-06 0.0032 3 48 .. 45 90 .. 43 111 .. 0.87
2 ? -2.8 0.0 4.2 4.1e+03 35 46 .. 140 151 .. 122 172 .. 0.70
Alignments for each domain:
== domain 1 score: 17.1 bits; conditional E-value: 3.3e-06
Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvs 48
+lD+ +G+G v fa +f+kv aid ++++l+ a ++ v
tr|H2XS49|H2XS49_CIOIN 45 FLLDVGCGGGQAVKIFAPYFDKVLAIDPSENQLEEARSQNKFAHVT 90
689******99999*******************9988777765554 PP
== domain 2 score: -2.8 bits; conditional E-value: 4.2
Methyltransf_15 35 lklaqhNaevYg 46
l+++++ a++Y+
tr|H2XS49|H2XS49_CIOIN 140 LQVCNKYAQIYN 151
555666666663 PP
>> tr|H2Y3J5|H2Y3J5_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 14.4 0.0 2.2e-05 0.022 3 38 .. 42 77 .. 40 96 .. 0.91
2 ? -3.5 0.1 6.9 6.8e+03 25 40 .. 145 160 .. 142 172 .. 0.51
Alignments for each domain:
== domain 1 score: 14.4 bits; conditional E-value: 2.2e-05
Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrlkla 38
++lD+ +GaG ++ fa + + v aid ++++lk a
tr|H2Y3J5|H2Y3J5_CIOIN 42 YLLDVGCGAGRSANVFAPYSHDVLAIDPSENELKEA 77
79*****************************99976 PP
== domain 2 score: -3.5 bits; conditional E-value: 6.9
Methyltransf_15 25 viaidinlsrlklaqh 40
v++++inl+ + q+
tr|H2Y3J5|H2Y3J5_CIOIN 145 VYCLEINLTYFFINQK 160
5555555554444333 PP
>> tr|F6RBS2|F6RBS2_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 PE=4 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 12.6 0.0 7.9e-05 0.078 5 47 .. 46 88 .. 43 117 .. 0.81
2 ? -1.8 0.0 2.1 2e+03 23 23 .. 219 219 .. 166 262 .. 0.63
Alignments for each domain:
== domain 1 score: 12.6 bits; conditional E-value: 7.9e-05
Methyltransf_15 5 lDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgv 47
+D+ +G+G ++ fa +f+kv a d + ++l+ a ++ +v
tr|F6RBS2|F6RBS2_CIOIN 46 VDVGCGSGQATNIFAPYFKKVLATDPSVNQLEHARMQNKFDNV 88
89****************************9988776666544 PP
== domain 2 score: -1.8 bits; conditional E-value: 2.1
Methyltransf_15 23 e 23
+
tr|F6RBS2|F6RBS2_CIOIN 219 R 219
1 PP
>> tr|F6UUI8|F6UUI8_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 GN=LOC100182889 PE=3 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? -1.1 0.0 1.3 1.3e+03 119 154 .. 48 84 .. 15 89 .. 0.73
2 ? -1.3 0.0 1.5 1.5e+03 60 87 .. 199 232 .. 125 253 .. 0.54
3 ? 11.5 0.1 0.00017 0.17 3 60 .. 429 485 .. 427 538 .. 0.81
Alignments for each domain:
== domain 1 score: -1.1 bits; conditional E-value: 1.3
Methyltransf_15 119 lfLPrnsdlkqlaalt.aevlenaskvkvvklkengl 154
LPr +l++l+ +++ n +k++vv+ ++ +
tr|F6UUI8|F6UUI8_CIOIN 48 GNLPRHCGYGELKKLMnKKLKLNPHKINVVSRINKAY 84
4699999999998865267888999999988777666 PP
== domain 2 score: -1.3 bits; conditional E-value: 1.5
Methyltransf_15 60 e.....llaklkleei...kvdlvflSpPwGGpsYk 87
+ l + k+e+ +d ++ Sp +GG Y+
tr|F6UUI8|F6UUI8_CIOIN 199 DnevfvWLMQQKKESGafcPMDDILPSPCVGG--YR 232
02233322222222211235566666666666..55 PP
== domain 3 score: 11.5 bits; conditional E-value: 0.00017
Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfe 60
+lD+++G+G ++ ++ +++di ++ + a +Na + ++ + ++ +g+ ++
tr|F6UUI8|F6UUI8_CIOIN 429 ALLDVCCGTGTIGLTLSSCVNRLVGVDICEQAIIDAVKNATLNNITNA-EFYVGKAED 485
68********99999*************************99987653.445555555 PP
>> tr|F6QVW6|F6QVW6_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 PE=3 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 13.3 0.0 4.9e-05 0.048 3 64 .. 20 81 .. 18 132 .. 0.84
Alignments for each domain:
== domain 1 score: 13.3 bits; conditional E-value: 4.9e-05
Methyltransf_15 3 vvlDlfgGaGGnviqfanv..fekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfellak 64
v++D+ GaGG + + + ++kvia+d +++ ++aq + + + ++ lg++ el +
tr|F6QVW6|F6QVW6_CIOIN 20 VIIDMTFGAGGHTKFIMENykHCKVIALDRDEKAFEIAQDLSKKF--KGRIIPLLGKFSELDKL 81
79*********9975544425789****************99999..99999999999885443 PP
>> sp|F7A355|TRM5_CIOIN tRNA (guanine(37)-N1)-methyltransferase OS=Ciona intestinalis OX=7719 PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 12.0 0.0 0.00012 0.12 3 46 .. 258 301 .. 256 339 .. 0.87
Alignments for each domain:
== domain 1 score: 12.0 bits; conditional E-value: 0.00012
Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYg 46
vv D+f+G G +i +a+ + v+a d n++ + hN +
sp|F7A355|TRM5_CIOIN 258 VVFDVFAGVGPFAIPIAKKGCVVYANDLNPESYRWLLHNVALNK 301
789************************************98764 PP
>> tr|I6L7H7|I6L7H7_CIOIN tRNA (guanine(37)-N1)-methyltransferase OS=Ciona intestinalis OX=7719 PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 12.1 0.0 0.00011 0.11 3 47 .. 277 321 .. 275 383 .. 0.87
Alignments for each domain:
== domain 1 score: 12.1 bits; conditional E-value: 0.00011
Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgv 47
vv D+f+G G +i +a+ + v+a d n++ + hN +
tr|I6L7H7|I6L7H7_CIOIN 277 VVFDVFAGVGPFAIPIAKKGCVVYANDLNPESYRWLLHNVALNKT 321
789************************************987644 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (165 nodes)
Target sequences: 16678 (5370518 residues searched)
Passed MSV filter: 605 (0.0362753); expected 333.6 (0.02)
Passed bias filter: 438 (0.0262621); expected 333.6 (0.02)
Passed Vit filter: 51 (0.00305792); expected 16.7 (0.001)
Passed Fwd filter: 17 (0.00101931); expected 0.2 (1e-05)
Initial search space (Z): 16678 [actual number of targets]
Domain search space (domZ): 17 [number of targets reported over threshold]
# CPU time: 0.10u 0.00s 00:00:00.10 Elapsed: 00:00:00.04
# Mc/sec: 22153.39
//
[ok]