# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/Methyltransf_15.hmm.txt
# target sequence database:        proteomes/Ciona_savignyi.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       Methyltransf_15  [M=165]
Accession:   PF09445.9
Description: RNA cap guanine-N2 methyltransferase
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
    5.8e-38  129.6   0.0    9.3e-38  128.9   0.0    1.3  1  tr|H2ZN24|H2ZN24_CIOSA  Uncharacterized protein OS=Ciona savi
    1.8e-07   30.4   0.2    2.7e-07   29.8   0.2    1.4  1  tr|H2ZQD2|H2ZQD2_CIOSA  Uncharacterized protein OS=Ciona savi
    0.00034   19.7   0.2     0.0022   17.1   0.1    2.5  2  tr|H2Y5Z4|H2Y5Z4_CIOSA  tRNA (guanine(37)-N1)-methyltransfera
     0.0036   16.4   0.1     0.0074   15.4   0.0    1.5  2  tr|H2Z3B7|H2Z3B7_CIOSA  Uncharacterized protein OS=Ciona savi
  ------ inclusion threshold ------
       0.02   14.0   0.0      0.022   13.9   0.0    1.1  1  tr|H2YEI9|H2YEI9_CIOSA  Uncharacterized protein OS=Ciona savi
      0.024   13.7   0.0      0.035   13.2   0.0    1.2  1  tr|H2YG63|H2YG63_CIOSA  Uncharacterized protein OS=Ciona savi


Domain annotation for each sequence (and alignments):
>> tr|H2ZN24|H2ZN24_CIOSA  Uncharacterized protein OS=Ciona savignyi OX=51511 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  128.9   0.0   4.8e-41   9.3e-38       2     164 ..     100     251 ..      99     252 .. 0.94

  Alignments for each domain:
  == domain 1  score: 128.9 bits;  conditional E-value: 4.8e-41
         Methyltransf_15   2 evvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfellaklkleeikvdlvflSpPwGGpsYkk 88 
                              +++D+f+G+GGn+iqfa + e+viaidi++ +l+ a hNa +Ygv+d++++++g +f+l  +l     k d++flSpPwGGp+Y +
  tr|H2ZN24|H2ZN24_CIOSA 100 DIIVDAFCGSGGNSIQFAFTCERVIAIDIDPVKLENARHNAAIYGVEDRIEFICGSFFDLAPTL-----KADVIFLSPPWGGPEYIH 181
                             689********************************************************98775.....45899************* PP

         Methyltransf_15  89 kekfdlekkleplklekllkesvklskniilfLPrnsdlkqlaaltaevlenaskvkvvklkenglvkallaylge 164
                              +++++   + ++  ek ++ + ++s+n+ +fLP+ns++++l +l    +++ ++v++ +   n+ +++l+ay+g 
  tr|H2ZN24|H2ZN24_CIOSA 182 CDTYSI-AAMGEF-GEKAFQLARNISDNVAFFLPKNSNVDELVRL----AGQGKHVELEQNMLNNKISTLTAYYGD 251
                             ******.888888.58999***********************988....899999*****************9985 PP

>> tr|H2ZQD2|H2ZQD2_CIOSA  Uncharacterized protein OS=Ciona savignyi OX=51511 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.8   0.2   1.4e-10   2.7e-07       3      87 ..      51     137 ..      49     181 .. 0.77

  Alignments for each domain:
  == domain 1  score: 29.8 bits;  conditional E-value: 1.4e-10
         Methyltransf_15   3 vvlDlfgGaGGnviqfanv.fekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfellaklk.leeikvdlvflSpPwGGpsYk 87 
                              v Dl +G+G  +i       +   ++di+++ l +   N+e Y+ ++ v++v+ dv +l +  + l++ ++d v++ pP G  s k
  tr|H2ZQD2|H2ZQD2_CIOSA  51 AVCDLGCGCGILSIGSSILgASYCLGVDIDKEALGIFLSNCEDYELESTVDCVHSDVVKLASCRNvLRKKQFDTVIMNPPFGTKSNK 137
                             5779999999888877666334589*********************************96543321233358*********976644 PP

>> tr|H2Y5Z4|H2Y5Z4_CIOSA  tRNA (guanine(37)-N1)-methyltransferase OS=Ciona savignyi OX=51511 PE=3 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.8   0.0      0.72   1.4e+03      60      81 ..       8      29 ..       2      48 .. 0.74
   2 !   17.1   0.1   1.1e-06    0.0022       3      61 ..     256     321 ..     254     416 .. 0.86

  Alignments for each domain:
  == domain 1  score: -1.8 bits;  conditional E-value: 0.72
         Methyltransf_15 60 ellaklkleeikvdlvflSpPw 81
                            +l+++l ++++  dl +lSpP+
  tr|H2Y5Z4|H2Y5Z4_CIOSA  8 NLFRRLVVNKMDSDLHVLSPPT 29
                            6778888899999999****96 PP

  == domain 2  score: 17.1 bits;  conditional E-value: 1.1e-06
         Methyltransf_15   3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfe.........l 61 
                             +v D+f+G G  +i +a+  + v+a d n++  k   hN ++   + +v++  +d  +         +
  tr|H2Y5Z4|H2Y5Z4_CIOSA 256 TVFDVFAGVGPFAIPIAKKGCLVYANDLNPDSYKWLVHNVKLN--KTEVECFNCDGRDfirdnlrnyI 321
                             589***************************************9..99999999998884444433332 PP

>> tr|H2Z3B7|H2Z3B7_CIOSA  Uncharacterized protein OS=Ciona savignyi OX=51511 PE=3 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.4   0.0   3.8e-06    0.0074      39      98 ..      19      79 ..      12     100 .. 0.85
   2 ?   -3.7   0.0       2.8   5.3e+03      71      80 ..     172     181 ..     154     185 .. 0.66

  Alignments for each domain:
  == domain 1  score: 15.4 bits;  conditional E-value: 3.8e-06
         Methyltransf_15 39 qhNaevYgvsdkvtlvlgdvfe...llaklkleeikvdlvflSpPwGGpsYkkkekfdlekkl 98
                            + N e+Y +  k  + + d++e   l++ +k +e  ++++++ pPw   s ++ +k+d   +l
  tr|H2Z3B7|H2Z3B7_CIOSA 19 KLNSEFYLIPAKSSFLMSDLKEigsLVEACKHKEK-FNCIVMDPPWENKSVRRGKKYDW-LSL 79
                            5699***************9998878999998887.9********************97.333 PP

  == domain 2  score: -3.7 bits;  conditional E-value: 2.8
         Methyltransf_15  71 kvdlvflSpP 80 
                               +lv++S+P
  tr|H2Z3B7|H2Z3B7_CIOSA 172 IKELVICSVP 181
                             3567777777 PP

>> tr|H2YEI9|H2YEI9_CIOSA  Uncharacterized protein OS=Ciona savignyi OX=51511 PE=3 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   0.0   1.1e-05     0.022      78     133 ..      41      99 ..      23     134 .. 0.83

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 1.1e-05
         Methyltransf_15  78 SpPwGGpsYkkk...ekfdlekkleplklekllkesvklskniilfLPrnsdlkqlaal 133
                               P GG s  k    ek  +e k  + ++ k++++++k  k+i  f P + +l+ +++ 
  tr|H2YEI9|H2YEI9_CIOSA  41 ANPFGGASHAKGivlEKIGVEAKQPNSAIRKCVRVQLKNGKKITAFVPNDGCLNYIEEN 99 
                             6799999999872225556888999*****************************99775 PP

>> tr|H2YG63|H2YG63_CIOSA  Uncharacterized protein OS=Ciona savignyi OX=51511 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.0   1.8e-05     0.035       4      39 ..      33      68 ..      31     103 .. 0.89

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 1.8e-05
         Methyltransf_15  4 vlDlfgGaGGnviqfanvfekviaidinlsrlklaq 39
                             lD+ +  GG + ++a  f+ vi+id++   +k ++
  tr|H2YG63|H2YG63_CIOSA 33 ALDIGCAVGGASFTLASKFDDVIGIDYSHGFVKTCN 68
                            79*************************998888775 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (165 nodes)
Target sequences:                        11592  (4231397 residues searched)
Passed MSV filter:                       391  (0.0337302); expected 231.8 (0.02)
Passed bias filter:                      277  (0.0238958); expected 231.8 (0.02)
Passed Vit filter:                        32  (0.00276052); expected 11.6 (0.001)
Passed Fwd filter:                         6  (0.000517598); expected 0.1 (1e-05)
Initial search space (Z):              11592  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.08u 0.00s 00:00:00.08 Elapsed: 00:00:00.03
# Mc/sec: 23272.68
//
[ok]