# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/Methyltransf_15.hmm.txt
# target sequence database: proteomes/Dictyostelium_discoideum.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: Methyltransf_15 [M=165]
Accession: PF09445.9
Description: RNA cap guanine-N2 methyltransferase
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
4.3e-32 110.6 0.2 7.6e-32 109.8 0.2 1.4 1 tr|Q54IS7|Q54IS7_DICDI Uncharacterized protein OS=Dictyostel
0.00016 20.9 0.0 0.00046 19.4 0.0 1.8 1 sp|Q54WD6|TRM5_DICDI tRNA (guanine(37)-N1)-methyltransfera
0.00021 20.5 0.1 0.00028 20.2 0.1 1.3 1 tr|Q54VE3|Q54VE3_DICDI Uncharacterized protein OS=Dictyostel
0.00095 18.4 0.2 0.002 17.4 0.0 1.6 2 tr|Q553T0|Q553T0_DICDI Uncharacterized protein OS=Dictyostel
0.0011 18.3 0.4 0.0041 16.4 0.1 2.1 2 tr|Q54C42|Q54C42_DICDI Uncharacterized protein OS=Dictyostel
0.0065 15.7 0.0 0.012 14.9 0.0 1.5 1 tr|Q54XZ7|Q54XZ7_DICDI Uncharacterized protein OS=Dictyostel
------ inclusion threshold ------
0.014 14.6 0.1 0.049 12.9 0.1 1.8 2 tr|Q557I0|Q557I0_DICDI Uncharacterized protein OS=Dictyostel
0.021 14.0 0.0 0.048 12.9 0.0 1.6 2 sp|Q55EX9|Y8948_DICDI Putative methyltransferase DDB_G02689
0.024 13.9 0.0 0.038 13.2 0.0 1.3 1 tr|Q54JJ5|Q54JJ5_DICDI Methyltransferase type 11 domain-cont
0.1 11.8 7.2 0.091 12.0 4.2 2.2 2 tr|Q55CK9|Q55CK9_DICDI Uncharacterized protein OS=Dictyostel
Domain annotation for each sequence (and alignments):
>> tr|Q54IS7|Q54IS7_DICDI Uncharacterized protein OS=Dictyostelium discoideum OX=44689 GN=DDB0187987 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 109.8 0.2 5.9e-35 7.6e-32 2 164 .. 173 332 .. 172 333 .. 0.87
Alignments for each domain:
== domain 1 score: 109.8 bits; conditional E-value: 5.9e-35
Methyltransf_15 2 evvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgv...sdkvtlvlgdvfellaklkleeikvdlvflSpPwGGps 85
++++Dlf+GaGGn+iqf + + v+++d ++ +l +a+hN vYg + ++++v d ++l +++k d++flSpPwGGp+
tr|Q54IS7|Q54IS7_DICDI 173 NTLVDLFCGAGGNTIQFSFTCNVVVSVDLDPMKLLMAKHNSWVYGHsseNTNIEFVNSDAMNL------SNLKADVIFLSPPWGGPN 253
679*****************************************9854567888998888765......445679************ PP
Methyltransf_15 86 YkkkekfdlekkleplklekllkesvklskniilfLPrnsdlkqlaalta..evlenaskvkvvklkenglvkallaylge 164
Y++ f l ++ p + +++k+++k++ n++ fLP+n+ ++a+l + + + ++ +++ + n +k+++ y+g+
tr|Q54IS7|Q54IS7_DICDI 254 YTDSSIFHL-DSMTPNGF-EIFKNAIKVTPNVVYFLPKNTSKVDIAKLALisKENGGSELCEIEENYINEKLKTITLYFGS 332
*********.99999776.599*****************99988888743113445678899***99***********985 PP
>> sp|Q54WD6|TRM5_DICDI tRNA (guanine(37)-N1)-methyltransferase OS=Dictyostelium discoideum OX=44689 GN=trmt5 PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 19.4 0.0 3.6e-07 0.00046 3 85 .. 216 299 .. 214 304 .. 0.92
Alignments for each domain:
== domain 1 score: 19.4 bits; conditional E-value: 3.6e-07
Methyltransf_15 3 vvlDlfgGaGGnviqfanv.fekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfellaklkleeikvdlvflSpPwGGps 85
++ D+f+G G + a++ +kv+a d n+s +k +++Na+ ++kv++ d + +++l +++i + v++ P ++
sp|Q54WD6|TRM5_DICDI 216 IICDMFAGVGPFALPAAKIkKCKVYANDLNPSSVKYMKENAKTNRLESKVEISNLDARDFVKSLVEKSIPFTHVVMNLPSTSIE 299
789*********9999998678***********************************************999999999976655 PP
>> tr|Q54VE3|Q54VE3_DICDI Uncharacterized protein OS=Dictyostelium discoideum OX=44689 GN=DDB0205190 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 20.2 0.1 2.2e-07 0.00028 3 70 .. 49 117 .. 47 169 .. 0.87
Alignments for each domain:
== domain 1 score: 20.2 bits; conditional E-value: 2.2e-07
Methyltransf_15 3 vvlDlfgGaGGnviqfanv.fekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfellaklkleei 70
vvlDl +G G vi a+ + i++din++ +k a++Na+ gv++ v +++ d+ + +kl++i
tr|Q54VE3|Q54VE3_DICDI 49 VVLDLGCGDGRIVIYAAKHyGIRGIGLDINPELIKSANENAKKEGVDHLVLFKVQDFANESFDFKLSSI 117
79************9999834578999******************************996666665544 PP
>> tr|Q553T0|Q553T0_DICDI Uncharacterized protein OS=Dictyostelium discoideum OX=44689 GN=DDB0202574 PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? -3.7 0.1 4.6 5.9e+03 18 38 .. 52 72 .. 43 80 .. 0.59
2 ! 17.4 0.0 1.5e-06 0.002 3 60 .. 242 300 .. 240 357 .. 0.88
Alignments for each domain:
== domain 1 score: -3.7 bits; conditional E-value: 4.6
Methyltransf_15 18 fanvfekviaidinlsrlkla 38
++ +kv +i+++ ++++
tr|Q553T0|Q553T0_DICDI 52 WTMQERKVGSIQMKATHIAKY 72
444445677777777777543 PP
== domain 2 score: 17.4 bits; conditional E-value: 1.5e-06
Methyltransf_15 3 vvlDlfgGaGGnviqfanv.fekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfe 60
+vlD+ +G GG + ++ ++ +k+ +++in++++ +a++ a+ gvsd+ + +gd ++
tr|Q553T0|Q553T0_DICDI 242 LVLDVGCGVGGPTLEICQYtGCKIRGLNINKKQVGIATQRAKDLGVSDRASFDHGDAMK 300
68*************9988799**********************************987 PP
>> tr|Q54C42|Q54C42_DICDI Uncharacterized protein OS=Dictyostelium discoideum OX=44689 GN=DDB0191845 PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? -1.4 0.0 0.9 1.1e+03 112 145 .. 55 88 .. 30 113 .. 0.62
2 ! 16.4 0.1 3.2e-06 0.0041 3 84 .. 430 514 .. 428 537 .. 0.77
Alignments for each domain:
== domain 1 score: -1.4 bits; conditional E-value: 0.9
Methyltransf_15 112 klskniilfLPrnsdlkqlaaltaevlenaskvk 145
+l + +i+ LP+ d k+ ++++ + + +k+k
tr|Q54C42|Q54C42_DICDI 55 TLHSMVIFGLPKYLDSKKFTKFLEQNNVPFKKIK 88
5555555555555555555555544444444444 PP
== domain 2 score: 16.4 bits; conditional E-value: 3.2e-06
Methyltransf_15 3 vvlDlfgGaG..GnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfellaklkleei...kvdlv.flSpPwGG 83
++lD+++G+G G++i + +kvi+++i+++ + + +Na++ + d+ ++ +g+ +++l +l +++ +++ ++ pP GG
tr|Q54C42|Q54C42_DICDI 430 TLLDICCGTGtiGQCIS--KKVKKVIGLEISPDAVIDSINNAKLNKI-DNAEYLVGKAEDTLPTLLTKSNggkDQEFIgIVDPPRGG 513
78********6667765..55689*******************9965.677889999888554444333332223444367788888 PP
Methyltransf_15 84 p 84
tr|Q54C42|Q54C42_DICDI 514 L 514
5 PP
>> tr|Q54XZ7|Q54XZ7_DICDI Uncharacterized protein OS=Dictyostelium discoideum OX=44689 GN=DDB0205497 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 14.9 0.0 9.2e-06 0.012 2 81 .. 143 244 .. 142 285 .. 0.85
Alignments for each domain:
== domain 1 score: 14.9 bits; conditional E-value: 9.2e-06
Methyltransf_15 2 evvlDlfgGaGGnviqfanvfekvia..idinlsrlklaqhNaevYgvsdkvtlvlgdvfe....................llaklk 66
+ +lDl +G+G n+f+ i+ id++ + l +a++Na +++v l d+++ ++ +
tr|Q54XZ7|Q54XZ7_DICDI 143 KKILDLGTGTGCLLLSTLNEFKDSIGvgIDKSNEALIIANKNAIELSLDKRVSLLNFDWNNydknqiskllsspsssspssSSNTNN 229
6799*******9999999999887751267778888999999999999*************99***********9999997444445 PP
Methyltransf_15 67 leeikvdlvflSpPw 81
+++ k+dlv+ pP
tr|Q54XZ7|Q54XZ7_DICDI 230 ENNEKFDLVISNPPY 244
555578999999994 PP
>> tr|Q557I0|Q557I0_DICDI Uncharacterized protein OS=Dictyostelium discoideum OX=44689 GN=DDB0168191 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? -2.9 0.0 2.8 3.5e+03 110 143 .. 162 195 .. 149 207 .. 0.70
2 ? 12.9 0.1 3.8e-05 0.049 24 80 .. 253 310 .. 237 315 .. 0.91
Alignments for each domain:
== domain 1 score: -2.9 bits; conditional E-value: 2.8
Methyltransf_15 110 svklskniilfLPrnsdlkqlaaltaevlenask 143
s+k ++ l+L + +l++ +++t+ + en k
tr|Q557I0|Q557I0_DICDI 162 STKDQQMSKLYLGKGYELDEANQTTLIIEENGMK 195
5555566668888888888888887777666555 PP
== domain 2 score: 12.9 bits; conditional E-value: 3.8e-05
Methyltransf_15 24 kviaidinlsrlklaqhNaevYgvsdkv.tlvlgdvfellaklkleeikvdlvflSpP 80
+++ id ++++ k a +N ++ g + + ++ + dvf+ l lk++++++d+++l pP
tr|Q557I0|Q557I0_DICDI 253 QTYNIDESIKNFKFADRNFKLNGLDTNYhKFSQKDVFTQLDYLKSKSTRFDVIVLDPP 310
5899********************766527899***********************99 PP
>> sp|Q55EX9|Y8948_DICDI Putative methyltransferase DDB_G0268948 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0268948 P
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 12.9 0.0 3.8e-05 0.048 3 44 .. 47 88 .. 45 118 .. 0.83
2 ? -2.6 0.0 2.2 2.7e+03 110 130 .. 186 206 .. 174 237 .. 0.70
Alignments for each domain:
== domain 1 score: 12.9 bits; conditional E-value: 3.8e-05
Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaev 44
+ +D+ +G+G ++ +a++f+kvi+ + ++ +++ a++ +v
sp|Q55EX9|Y8948_DICDI 47 LAIDIGAGSGQATVRLAKYFKKVIGFEPSQGQIENAEKTDNV 88
579***************************999998875544 PP
== domain 2 score: -2.6 bits; conditional E-value: 2.2
Methyltransf_15 110 svklskniilfLPrnsdlkql 130
s++ + + + LP++ ++++
sp|Q55EX9|Y8948_DICDI 186 SFENTTRKTISLPKSMSINDM 206
455555556667777777766 PP
>> tr|Q54JJ5|Q54JJ5_DICDI Methyltransferase type 11 domain-containing protein OS=Dictyostelium discoideum OX=44689 GN=D
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 13.2 0.0 3e-05 0.038 3 40 .. 45 82 .. 43 109 .. 0.87
Alignments for each domain:
== domain 1 score: 13.2 bits; conditional E-value: 3e-05
Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqh 40
+ +D +G+G ++++a++f+kvi+ + ++ +++ a +
tr|Q54JJ5|Q54JJ5_DICDI 45 LAIDCGCGSGQATVKLAKYFKKVIGFEPSQGQIENAVK 82
579************************99999887765 PP
>> tr|Q55CK9|Q55CK9_DICDI Uncharacterized protein OS=Dictyostelium discoideum OX=44689 GN=DDB0190741 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 12.0 4.2 7.1e-05 0.091 10 97 .. 32 130 .. 25 180 .. 0.76
2 ? 0.2 0.0 0.29 3.7e+02 119 144 .. 229 254 .. 209 291 .. 0.77
Alignments for each domain:
== domain 1 score: 12.0 bits; conditional E-value: 7.1e-05
Methyltransf_15 10 GaG.GnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfe............llaklkleeikvdlvflSpPwGG 83
G G G +++fa+ +kvi i n+++lk + +N ++ ++k +++ d+++ + + k+++ v++++ G
tr|Q55CK9|Q55CK9_DICDI 32 GIGlGITNEFAKKGCKVILIGRNENKLKNIIENIKIQFGNEKCYYICSDLTKeedfknckqeieNI-SNKFGQY-VEILVNCAGSGT 116
5555899*****************************989**********99888777776654311.1133333.566666666666 PP
Methyltransf_15 84 psYkkkekfdlekk 97
+Y ++++f +++
tr|Q55CK9|Q55CK9_DICDI 117 WKYIEDTSFKECNE 130
66666666665554 PP
== domain 2 score: 0.2 bits; conditional E-value: 0.29
Methyltransf_15 119 lfLPrnsdlkqlaaltaevlena.skv 144
+LP+ + ++q+++ t++ +en+ +++
tr|Q55CK9|Q55CK9_DICDI 229 KYLPK-VSIDQISKATISAIENRkQRI 254
58997.679999998887665541455 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (165 nodes)
Target sequences: 12739 (6856946 residues searched)
Passed MSV filter: 888 (0.0697072); expected 254.8 (0.02)
Passed bias filter: 216 (0.0169558); expected 254.8 (0.02)
Passed Vit filter: 30 (0.00235497); expected 12.7 (0.001)
Passed Fwd filter: 10 (0.000784991); expected 0.1 (1e-05)
Initial search space (Z): 12739 [actual number of targets]
Domain search space (domZ): 10 [number of targets reported over threshold]
# CPU time: 0.12u 0.01s 00:00:00.13 Elapsed: 00:00:00.06
# Mc/sec: 18856.60
//
[ok]