# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/Methyltransf_15.hmm.txt
# target sequence database: proteomes/Monodelphis_domestica.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: Methyltransf_15 [M=165]
Accession: PF09445.9
Description: RNA cap guanine-N2 methyltransferase
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
2.7e-42 144.5 0.0 5.4e-42 143.5 0.0 1.6 1 tr|F7ADF5|F7ADF5_MONDO Trimethylguanosine synthase 1 OS=Mono
4e-05 23.6 0.0 0.00012 22.1 0.0 1.6 2 tr|F7B9I4|F7B9I4_MONDO HemK methyltransferase family member
0.00015 21.8 0.0 0.00029 20.8 0.0 1.4 1 tr|F6S9Y2|F6S9Y2_MONDO tRNA methyltransferase 2 homolog A OS
0.00022 21.2 0.0 0.0005 20.0 0.0 1.6 1 tr|F6PG51|F6PG51_MONDO tRNA (guanine(37)-N1)-methyltransfera
------ inclusion threshold ------
0.02 14.9 0.0 0.032 14.2 0.0 1.3 1 tr|F7FNT7|F7FNT7_MONDO NOP2/Sun RNA methyltransferase family
0.044 13.7 0.0 0.07 13.1 0.0 1.3 1 tr|F7CVG3|F7CVG3_MONDO Uncharacterized protein OS=Monodelphi
0.15 12.0 0.0 0.25 11.3 0.0 1.3 1 tr|F7F1Z8|F7F1Z8_MONDO Ubiquinone biosynthesis O-methyltrans
0.22 11.5 0.0 0.34 10.8 0.0 1.2 1 tr|H9H7D7|H9H7D7_MONDO Uncharacterized protein OS=Monodelphi
0.24 11.4 0.2 22 5.0 0.0 2.2 2 tr|F7AGN8|F7AGN8_MONDO Enoyl-CoA delta isomerase 1 OS=Monode
Domain annotation for each sequence (and alignments):
>> tr|F7ADF5|F7ADF5_MONDO Trimethylguanosine synthase 1 OS=Monodelphis domestica OX=13616 GN=TGS1 PE=4 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 143.5 0.0 2.3e-45 5.4e-42 2 163 .. 581 732 .. 580 734 .. 0.93
Alignments for each domain:
== domain 1 score: 143.5 bits; conditional E-value: 2.3e-45
Methyltransf_15 2 evvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfellaklkleeikvdlvflSpPwGGpsYkk 88
+++D+f+G GGn+iqfa++ ++viaidi++ ++ la++NaevYgv+dk+++++gd++ l + l k d+vflSpPwGGp+Y
tr|F7ADF5|F7ADF5_MONDO 581 DIIVDAFCGVGGNAIQFALTGKRVIAIDIDPAKIDLAHNNAEVYGVADKIEFICGDFMLLASDL-----KADVVFLSPPWGGPDYAT 662
689******************************************************9777664.....5599************** PP
Methyltransf_15 89 kekfdlekkleplklekllkesvklskniilfLPrnsdlkqlaaltaevlenaskvkvvklkenglvkallaylg 163
e+fd+++ ++p + ++++ s ++kni+ fLPrn+d++q+a+l +++ +v++ + n+ +k+++ay+g
tr|F7ADF5|F7ADF5_MONDO 663 AETFDIRTMMSPDGF-EIFRLSQMITKNIVYFLPRNADIDQVASL----AGPGGQVEIEQNFLNNKLKTITAYFG 732
******888887666.6999**********************998....89***********************8 PP
>> tr|F7B9I4|F7B9I4_MONDO HemK methyltransferase family member 1 OS=Monodelphis domestica OX=13616 GN=HEMK1 PE=4 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? -2.1 0.0 1.4 3.3e+03 97 145 .. 107 156 .. 96 163 .. 0.63
2 ! 22.1 0.0 5e-08 0.00012 3 80 .. 173 253 .. 172 254 .. 0.87
Alignments for each domain:
== domain 1 score: -2.1 bits; conditional E-value: 1.4
Methyltransf_15 97 kleplklekllke..svklsknii..lfLPrnsdlkqlaaltaevlenaskvk 145
+l+ ++++ ++ e + l+ ++ +f+Pr ++++l +l ++e++++++
tr|F7B9I4|F7B9I4_MONDO 107 RLQRMPVQYVIGEwdFQGLTLKMTppVFIPRP-ETEELVNLV--LHEQSQRCQ 156
55555555555555544455555555788886.567777774..888888886 PP
== domain 2 score: 22.1 bits; conditional E-value: 5e-08
Methyltransf_15 3 vvlDlfgGaGGnviqfanv..fekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfellaklkleei.kvdlvflSpP 80
++lD+++G+G + + ++v+a+d+ ++ ++l+ +Na+ +d++++v d+++ +++ +l vd+v+ pP
tr|F7B9I4|F7B9I4_MONDO 173 LILDVCCGSGAIALSLLSKltQSRVVAVDKGEEAVQLTRENAQRLHLEDRIQIVRHDITSGVNREQLLPWgPVDFVVSNPP 253
58********99888755444789************************************999887766667899998888 PP
>> tr|F6S9Y2|F6S9Y2_MONDO tRNA methyltransferase 2 homolog A OS=Monodelphis domestica OX=13616 GN=TRMT2A PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 20.8 0.0 1.2e-07 0.00029 3 69 .. 447 512 .. 445 536 .. 0.85
Alignments for each domain:
== domain 1 score: 20.8 bits; conditional E-value: 1.2e-07
Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfellaklklee 69
+vlD+++G+G +a++ ++vi+i+ ++ ++ a Na++ d++++ +g+ ++l+ +l ++
tr|F6S9Y2|F6S9Y2_MONDO 447 TVLDVCCGTGTIGLSLAQTVKRVIGIELCQEAVEDARVNAKMN-ALDNIEFHCGKAEDLVPSLMSSL 512
58***************************************98.99**********99877665544 PP
>> tr|F6PG51|F6PG51_MONDO tRNA (guanine(37)-N1)-methyltransferase OS=Monodelphis domestica OX=13616 GN=TRMT5 PE=3 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 20.0 0.0 2.1e-07 0.0005 3 62 .. 303 362 .. 301 398 .. 0.88
Alignments for each domain:
== domain 1 score: 20.0 bits; conditional E-value: 2.1e-07
Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfell 62
v+ D+f+G G +i +a+ ++v+a d n++ k hN+++ v++kv++ d ++ l
tr|F6PG51|F6PG51_MONDO 303 VLFDVFAGVGPFAIPVAKKDCTVFANDLNPESYKWLLHNCKLNKVDQKVKIFNLDGKDFL 362
689**********************************************99887776644 PP
>> tr|F7FNT7|F7FNT7_MONDO NOP2/Sun RNA methyltransferase family member 6 OS=Monodelphis domestica OX=13616 GN=NSUN6 PE=
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 14.2 0.0 1.3e-05 0.032 3 84 .. 237 327 .. 235 361 .. 0.75
Alignments for each domain:
== domain 1 score: 14.2 bits; conditional E-value: 1.3e-05
Methyltransf_15 3 vvlDlfgGaGGnviqfanv...fekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfellaklkleei.......kvdlvflSp 79
+lD+++ GG++ ++a +via+d+ +s+++ +++Na + + + +++ +++l k++ ++ ++d ++l
tr|F7FNT7|F7FNT7_MONDO 237 KILDMCAAPGGKTTHIAALmrdQGEVIAMDKIPSKVEKIKQNAALL-QLNCIRAFCCNGTKALGKIEDGQGgppfspeSFDRILLDA 322
79**************998555458*******************99.5678999999988888777665543334444455555555 PP
Methyltransf_15 80 PwGGp 84
P G+
tr|F7FNT7|F7FNT7_MONDO 323 PCSGM 327
55555 PP
>> tr|F7CVG3|F7CVG3_MONDO Uncharacterized protein OS=Monodelphis domestica OX=13616 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 13.1 0.0 3e-05 0.07 3 61 .. 237 297 .. 235 329 .. 0.82
Alignments for each domain:
== domain 1 score: 13.1 bits; conditional E-value: 3e-05
Methyltransf_15 3 vvlDlfgGaGGnviqfanv....fekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfel 61
v++Dl++G G + f f v+a++ +++ + ++N e+ gvsd+ + lgd +l
tr|F7CVG3|F7CVG3_MONDO 237 VLVDLYAGIGYFTLPFLIHanaaF--VHACEWDPHAAAALKKNLELNGVSDRCSIHLGDNRKL 297
789999999998866643333226..*********************************8774 PP
>> tr|F7F1Z8|F7F1Z8_MONDO Ubiquinone biosynthesis O-methyltransferase, mitochondrial OS=Monodelphis domestica OX=13616
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 11.3 0.0 0.00011 0.25 3 78 .. 146 219 .. 144 223 .. 0.88
Alignments for each domain:
== domain 1 score: 11.3 bits; conditional E-value: 0.00011
Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgv.sdkvtlvlgdvfellaklkleeikvdlvflS 78
+lD+ +G+G + + + v +id +++k aq+ + + +++++++ + ++++++++ e+ d v++S
tr|F7F1Z8|F7F1Z8_MONDO 146 KILDVGCGGGLLCEPLGRLGALVTGIDPLNENIKTAQQHKSFDPIlDKRIQYKACILEDIVEET-AESF--DAVVAS 219
58***********************************999998886889******999999984.3444..777776 PP
>> tr|H9H7D7|H9H7D7_MONDO Uncharacterized protein OS=Monodelphis domestica OX=13616 PE=4 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 10.8 0.0 0.00015 0.34 7 77 .. 111 186 .. 106 188 .. 0.87
Alignments for each domain:
== domain 1 score: 10.8 bits; conditional E-value: 0.00015
Methyltransf_15 7 lfgGaGGnviqfanv...fekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfellaklkleei..kvdlvfl 77
l + +G +i +a+ + ++i+ n+s +a + ++ g +dk+ + +g +e++ +lk+++ +vdlvfl
tr|H9H7D7|H9H7D7_MONDO 111 LGTYCGYSAIRMARLlppGARLFTIEFNESFASIASQMIQLAGLQDKISILKGSTQEIIPQLKKKHEisTVDLVFL 186
555678889999999788889**************************************999887655789***97 PP
>> tr|F7AGN8|F7AGN8_MONDO Enoyl-CoA delta isomerase 1 OS=Monodelphis domestica OX=13616 GN=ECI1 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 5.0 0.0 0.0093 22 39 87 .. 66 110 .. 42 128 .. 0.64
2 ? 4.5 0.1 0.013 31 96 140 .. 208 252 .. 200 254 .] 0.86
Alignments for each domain:
== domain 1 score: 5.0 bits; conditional E-value: 0.0093
Methyltransf_15 39 qhNaevYgvsdkvtlvlgdvfellaklkleeikvdlvflSpPwGGpsYk 87
h ae++ ++++l+l + + + ++i+ +++f S P GG +
tr|F7AGN8|F7AGN8_MONDO 66 AHYAEFWKAVQELWLKLY----MSNMVVIAAINASCLFGSSPAGGCLIS 110
555555555555554443....2233445567788**********7655 PP
== domain 2 score: 4.5 bits; conditional E-value: 0.013
Methyltransf_15 96 kkleplklekllkesvklskniilfLPrnsdlkqlaaltaevlen 140
+ +++ ++++llk+ kn++ f+ r+s k+l+ +++++ e+
tr|F7AGN8|F7AGN8_MONDO 208 TMMRKPTVDRLLKQREADIKNFVSFISRDSIQKSLHMYMKHLKER 252
3788999****************************9998887665 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (165 nodes)
Target sequences: 21272 (11266248 residues searched)
Passed MSV filter: 760 (0.0357277); expected 425.4 (0.02)
Passed bias filter: 565 (0.0265607); expected 425.4 (0.02)
Passed Vit filter: 49 (0.0023035); expected 21.3 (0.001)
Passed Fwd filter: 9 (0.000423091); expected 0.2 (1e-05)
Initial search space (Z): 21272 [actual number of targets]
Domain search space (domZ): 9 [number of targets reported over threshold]
# CPU time: 0.17u 0.01s 00:00:00.18 Elapsed: 00:00:00.08
# Mc/sec: 23236.64
//
[ok]