# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/Methyltransf_15.hmm.txt # target sequence database: proteomes/Natronomonas_moolapensis.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: Methyltransf_15 [M=165] Accession: PF09445.9 Description: RNA cap guanine-N2 methyltransferase Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4e-05 20.7 0.0 5.6e-05 20.3 0.0 1.2 1 tr|M1Y3X8|M1Y3X8_NATM8 tRNA (Guanine(37)-N(1))-methyltransfe 7e-05 19.9 0.0 9.1e-05 19.6 0.0 1.2 1 tr|M1XN99|M1XN99_NATM8 tRNA(Phe) (4-demethylwyosine(37)-C(7) 0.00021 18.4 0.0 0.00023 18.2 0.0 1.2 1 tr|M1Y4D2|M1Y4D2_NATM8 Probable S-adenosylmethionine-depende 0.00096 16.2 0.0 0.0017 15.4 0.0 1.4 2 tr|M1XS10|M1XS10_NATM8 Probable rRNA methyltransferase OS=Na 0.0025 14.9 0.0 0.0035 14.4 0.0 1.2 1 tr|M1XLF5|M1XLF5_NATM8 tRNA (Guanine(10),N(2))-dimethyltrans 0.0043 14.1 0.0 0.006 13.6 0.0 1.2 1 tr|M1XL08|M1XL08_NATM8 Probable arsenite(III)-methyltransfer 0.0077 13.3 0.0 0.011 12.8 0.0 1.2 1 tr|M1XLH6|M1XLH6_NATM8 Homolog to S-adenosylmethionine-depen ------ inclusion threshold ------ 0.016 12.3 0.0 0.027 11.5 0.0 1.3 1 tr|M1Y1K5|M1Y1K5_NATM8 Site-specific DNA-methyltransferase ( Domain annotation for each sequence (and alignments): >> tr|M1Y3X8|M1Y3X8_NATM8 tRNA (Guanine(37)-N(1))-methyltransferase OS=Natronomonas moolapensis (strain DSM 18674 / JCM # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.3 0.0 1.6e-07 5.6e-05 3 61 .. 180 238 .. 178 286 .. 0.89 Alignments for each domain: == domain 1 score: 20.3 bits; conditional E-value: 1.6e-07 Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfel 61 v D+f+G G ++ a+ + +++d n+ ++ +Nae gvsd+v + +dv ++ tr|M1Y3X8|M1Y3X8_NATM8 180 RVFDMFAGVGPFIVPAAKRGAECVGVDLNEAAVEYLRRNAERNGVSDRVIAINADVRDV 238 689****************************************************9873 PP >> tr|M1XN99|M1XN99_NATM8 tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase OS=Natronomonas moolapen # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.6 0.0 2.7e-07 9.1e-05 3 61 .. 198 256 .. 196 304 .. 0.87 Alignments for each domain: == domain 1 score: 19.6 bits; conditional E-value: 2.7e-07 Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfel 61 v D+f+G G + +a+ +v a +i+++ + +Na+ gv+ +v+ vlgd+ ++ tr|M1XN99|M1XN99_NATM8 198 RVFDMFAGIGYFSLPMARAEASVTAAEIDPTAHRRLVENARRNGVAARVEAVLGDCRSV 256 689*****************************************************883 PP >> tr|M1Y4D2|M1Y4D2_NATM8 Probable S-adenosylmethionine-dependent methyltransferase OS=Natronomonas moolapensis (strain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.2 0.0 6.8e-07 0.00023 3 60 .. 47 104 .. 45 175 .. 0.84 Alignments for each domain: == domain 1 score: 18.2 bits; conditional E-value: 6.8e-07 Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfe 60 +l + +G+G ++ +a ++++di++ l++ + a+ gv++ + +++gd tr|M1Y4D2|M1Y4D2_NATM8 47 RILEVACGTGRFTVMLADRGADIVGMDISEAMLEQGRRKARSAGVDESLSFIQGDAGR 104 6899***************************************************876 PP >> tr|M1XS10|M1XS10_NATM8 Probable rRNA methyltransferase OS=Natronomonas moolapensis (strain DSM 18674 / JCM 14361 / 8 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.4 0.0 4.9e-06 0.0017 2 82 .. 56 133 .. 55 162 .. 0.82 2 ? -2.9 0.0 2.2 7.5e+02 8 23 .. 171 188 .. 164 208 .. 0.65 Alignments for each domain: == domain 1 score: 15.4 bits; conditional E-value: 4.9e-06 Methyltransf_15 2 evvlDlfgGaGGnviqfanvf.ekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfellaklkleeikvdlvflSpPwG 82 ++vlDl +G+G + a+ e v+++di++ l a +N + g v +v gdv++l ++ v++ pP G tr|M1XS10|M1XS10_NATM8 56 RTVLDLGCGTGMLALGAALRGpELVVGVDIDPAPLSTARENERRVGAMTDVSWVRGDVTDLPLVPGGDA----TVLMNPPFG 133 579***************99624699********************************98533322222....355555555 PP == domain 2 score: -2.9 bits; conditional E-value: 2.2 Methyltransf_15 8 fgG.aGGnviq.fanvfe 23 f+G GG+v + fa +fe tr|M1XS10|M1XS10_NATM8 171 FAGdNGGQVTHaFAAEFE 188 555346665432666664 PP >> tr|M1XLF5|M1XLF5_NATM8 tRNA (Guanine(10),N(2))-dimethyltransferase OS=Natronomonas moolapensis (strain DSM 18674 / J # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.4 0.0 1e-05 0.0035 3 45 .. 178 220 .. 176 242 .. 0.92 Alignments for each domain: == domain 1 score: 14.4 bits; conditional E-value: 1e-05 Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevY 45 +lD+++G+GG ++ + +v+++d + + ++ +++N +Y tr|M1XLF5|M1XLF5_NATM8 178 RILDPMCGTGGILVEAGLAGASVVGVDAQAKMVRGTERNLAAY 220 68**************************************999 PP >> tr|M1XL08|M1XL08_NATM8 Probable arsenite(III)-methyltransferase OS=Natronomonas moolapensis (strain DSM 18674 / JCM # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.6 0.0 1.8e-05 0.006 3 61 .. 98 158 .. 96 187 .. 0.79 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 1.8e-05 Methyltransf_15 3 vvlDlfgGaGGnviqfanv...fekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfel 61 vlDl +GaG ++ a++ +vi++d+ ++ +k a Na g +++v++ lg++++l tr|M1XL08|M1XL08_NATM8 98 AVLDLGSGAGFDCFLAAQEvgeTGRVIGVDMTPEMIKKARANASQNG-AENVEFRLGEIEHL 158 69***********999998777669******************9985.67899999998874 PP >> tr|M1XLH6|M1XLH6_NATM8 Homolog to S-adenosylmethionine-dependent methyltransferase OS=Natronomonas moolapensis (stra # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.8 0.0 3.2e-05 0.011 4 76 .. 40 108 .. 38 132 .. 0.84 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 3.2e-05 Methyltransf_15 4 vlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfellaklkleeikvdlvf 76 lD+ +G+G n+ +a+ v a+d++ + l+ a + a gv vt++ +d+++ l++++ dl+ tr|M1XLH6|M1XLH6_NATM8 40 ALDVATGTGRNALYLAEHGYDVEAVDVSDEALARARRRADERGV--DVTWIRADLTDPGFDLETGAY--DLIT 108 69****************99*******************99977..599999999874443333333..5554 PP >> tr|M1Y1K5|M1Y1K5_NATM8 Site-specific DNA-methyltransferase (Cytosine-specific) OS=Natronomonas moolapensis (strain D # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 0.0 8e-05 0.027 4 33 .. 5 35 .. 3 54 .. 0.78 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 8e-05 Methyltransf_15 4 vlDlfgGaGGnviqfanvfekv.iaidinls 33 +Dlf+GaGG ++ +++ v +idi+++ tr|M1Y1K5|M1Y1K5_NATM8 5 AIDLFCGAGGLTNGLERAGICVeAGIDIDPD 35 69**************996555256888765 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (165 nodes) Target sequences: 2723 (809592 residues searched) Passed MSV filter: 50 (0.0183621); expected 54.5 (0.02) Passed bias filter: 50 (0.0183621); expected 54.5 (0.02) Passed Vit filter: 15 (0.00550863); expected 2.7 (0.001) Passed Fwd filter: 8 (0.00293794); expected 0.0 (1e-05) Initial search space (Z): 2723 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.01 # Mc/sec: 13358.27 // [ok]