# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/Methyltransf_15.hmm.txt
# target sequence database: proteomes/Pan_troglodytes.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: Methyltransf_15 [M=165]
Accession: PF09445.9
Description: RNA cap guanine-N2 methyltransferase
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
1.3e-41 142.5 0.1 3.8e-41 140.9 0.0 1.9 2 tr|H2QW66|H2QW66_PANTR Trimethylguanosine synthase 1 OS
0.00067 19.7 0.0 0.0012 18.9 0.0 1.3 1 tr|K7BSP4|K7BSP4_PANTR HEMK1 isoform 1 OS=Pan troglodyt
0.0019 18.3 0.0 0.0029 17.7 0.0 1.2 1 tr|H2QL91|H2QL91_PANTR COMT isoform 1 OS=Pan troglodyte
0.0021 18.1 0.0 0.0047 17.0 0.0 1.6 1 tr|H2Q8F0|H2Q8F0_PANTR tRNA (guanine(37)-N1)-methyltran
0.0044 17.1 0.0 0.0075 16.3 0.0 1.3 1 tr|H2QL94|H2QL94_PANTR TRM2 tRNA methyltransferase 2 ho
------ inclusion threshold ------
0.019 15.0 0.0 0.03 14.4 0.0 1.3 1 tr|H2QTG0|H2QTG0_PANTR Ubiquinone biosynthesis O-methyl
0.028 14.5 0.0 0.075 13.1 0.0 1.8 2 tr|H2R4E3|H2R4E3_PANTR TRMT11 isoform 3 OS=Pan troglody
0.073 13.1 0.0 0.13 12.3 0.0 1.5 1 tr|H2Q1P7|H2Q1P7_PANTR NOP2/Sun RNA methyltransferase f
0.14 12.2 0.0 0.56 10.3 0.0 2.0 2 tr|H2QHS9|H2QHS9_PANTR THUMP domain containing 2 OS=Pan
0.15 12.1 0.0 0.24 11.5 0.0 1.3 1 tr|A0A2J8JEW0|A0A2J8JEW0_PANTR NOP2 isoform 16 OS=Pan troglodyt
Domain annotation for each sequence (and alignments):
>> tr|H2QW66|H2QW66_PANTR Trimethylguanosine synthase 1 OS=Pan troglodytes OX=9598 GN=TGS1 PE=4 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? -2.4 0.0 1.8 4.2e+03 72 96 .. 150 175 .. 114 181 .. 0.54
2 ! 140.9 0.0 1.6e-44 3.8e-41 2 163 .. 694 845 .. 693 847 .. 0.92
Alignments for each domain:
== domain 1 score: -2.4 bits; conditional E-value: 1.8
Methyltransf_15 72 vdlvflS.pPwGGpsYkkkekfdlek 96
d +++S P +Y+++ +++l++
tr|H2QW66|H2QW66_PANTR 150 EDDILASdDPSSIEQYENTRTYELQS 175
33333331355555666666666655 PP
== domain 2 score: 140.9 bits; conditional E-value: 1.6e-44
Methyltransf_15 2 evvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfellaklkleeikvdlvflSpPwGGpsYkk 88
vv+D+f+G GGn+iqfa++ +viaidi++ +++la +NaevYg++dk+++++gd+ l + l k d+vflSpPwGGp+Y
tr|H2QW66|H2QW66_PANTR 694 DVVVDAFCGVGGNTIQFALTGMRVIAIDIDPVKIALARNNAEVYGIADKIEFICGDFLLLASCL-----KADVVFLSPPWGGPDYAT 775
689*****************************************************98655443.....4589************** PP
Methyltransf_15 89 kekfdlekkleplklekllkesvklskniilfLPrnsdlkqlaaltaevlenaskvkvvklkenglvkallaylg 163
e+fd+++ ++p + ++++ s k+++ni+ fLPrn+d++q+a+l +++ +v++ + n+ +k+++ay+g
tr|H2QW66|H2QW66_PANTR 776 AETFDIRTMMSPDGF-EIFRLSKKITNNIVYFLPRNADIDQVASL----AGPGGQVEIEQNFLNNKLKTITAYFG 845
******878877665.699***********************998....89***********************8 PP
>> tr|K7BSP4|K7BSP4_PANTR HEMK1 isoform 1 OS=Pan troglodytes OX=9598 GN=HEMK1 PE=2 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 18.9 0.0 5.2e-07 0.0012 4 80 .. 163 241 .. 161 253 .. 0.82
Alignments for each domain:
== domain 1 score: 18.9 bits; conditional E-value: 5.2e-07
Methyltransf_15 4 vlDlfgGaGGnviqfanv..fekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfellaklkleeikvdlvflSpP 80
+l + +G+G + + + ++via+d+ + + l+++Na+ +d++++++ d+++ + ++l vdl++ pP
tr|K7BSP4|K7BSP4_PANTR 163 ILEVGCGSGAISLSLLSQlpQSRVIAVDKGEAAISLTHENAQRLRLQDRIWIIHLDMTSERSWTHLPWGPVDLIVSNPP 241
56666666666655555466789**********************************9966666666666699999998 PP
>> tr|H2QL91|H2QL91_PANTR COMT isoform 1 OS=Pan troglodytes OX=9598 GN=COMT PE=2 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 17.7 0.0 1.2e-06 0.0029 6 77 .. 114 190 .. 110 192 .. 0.86
Alignments for each domain:
== domain 1 score: 17.7 bits; conditional E-value: 1.2e-06
Methyltransf_15 6 DlfgGaGGnviqfanv...fekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfellaklkleei..kvdlvfl 77
l + +G ++ +a+ + i+i+in++ +++q+ + gv+dkvtlv+g ++++ +lk++ + d+vfl
tr|H2QL91|H2QL91_PANTR 114 ELGAYCGYSAVRMARLlspGARLITIEINPDCAAITQRMVDFAGVKDKVTLVVGASQDIIPQLKKKYDvdTLDMVFL 190
5556677788889988777889*************************************999998876568899996 PP
>> tr|H2Q8F0|H2Q8F0_PANTR tRNA (guanine(37)-N1)-methyltransferase OS=Pan troglodytes OX=9598 GN=TRMT5 PE=3 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 17.0 0.0 2.1e-06 0.0047 3 64 .. 300 361 .. 298 394 .. 0.87
Alignments for each domain:
== domain 1 score: 17.0 bits; conditional E-value: 2.1e-06
Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfellak 64
v+ D+f+G G +i +a+ ++v+a d n++ k N+++ v++kv++ d ++ l+
tr|H2Q8F0|H2Q8F0_PANTR 300 VLFDVFAGVGPFAIPVAKKNCTVFANDLNPESHKWLLYNCKLNKVDQKVKVFNLDGKDFLQG 361
689***********************************************999888776655 PP
>> tr|H2QL94|H2QL94_PANTR TRM2 tRNA methyltransferase 2 homolog A OS=Pan troglodytes OX=9598 GN=TRMT2A PE=2 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 16.3 0.0 3.3e-06 0.0075 3 83 .. 435 515 .. 433 519 .. 0.83
Alignments for each domain:
== domain 1 score: 16.3 bits; conditional E-value: 3.3e-06
Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfellaklkleeikvdlv.flSpPwGG 83
+vlD+++G+G ++a+ ++vi+++ ++ ++ a Na+ ++v++ +g ++l+ +l ++ ++ lv +l pP G
tr|H2QL94|H2QL94_PANTR 435 TVLDVCCGTGTIGLALARKVKRVIGVELCPEAVEDARVNAQDN-ELSNVEFHCGRAEDLVPTLVSRLASQHLVaILDPPRAG 515
69***************************************87.5679*****99999877766665544444256777666 PP
>> tr|H2QTG0|H2QTG0_PANTR Ubiquinone biosynthesis O-methyltransferase, mitochondrial OS=Pan troglodytes OX=9598 GN=COQ3
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 14.4 0.0 1.3e-05 0.03 3 78 .. 149 222 .. 147 225 .. 0.87
Alignments for each domain:
== domain 1 score: 14.4 bits; conditional E-value: 1.3e-05
Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgv.sdkvtlvlgdvfellaklkleeikvdlvflS 78
+lD+ +G+G + + + +vi+id +++k aq + v ++++++ ++ ++e+++++ e+ +d v++S
tr|H2QTG0|H2QTG0_PANTR 149 KILDVGCGGGLLTEPLGRLGASVIGIDPVDENIKTAQCHKSFDPVlDKRIEYRVCSLEEIVEET-AET--FDAVVAS 222
58*****************************999999888888886899************983.333..4888887 PP
>> tr|H2R4E3|H2R4E3_PANTR TRMT11 isoform 3 OS=Pan troglodytes OX=9598 GN=TRMT11 PE=2 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? -3.4 0.0 3.8 8.7e+03 43 64 .. 91 112 .. 82 123 .. 0.60
2 ? 13.1 0.0 3.2e-05 0.075 3 43 .. 218 262 .. 216 316 .. 0.77
Alignments for each domain:
== domain 1 score: -3.4 bits; conditional E-value: 3.8
Methyltransf_15 43 evYgvsdkvtlvlgdvfellak 64
+ Y v++ v + + d + ++
tr|H2R4E3|H2R4E3_PANTR 91 KNYPVEKMVPFLHSDSTYKIKI 112
4466666666666665554444 PP
== domain 2 score: 13.1 bits; conditional E-value: 3.2e-05
Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrl....klaqhNae 43
+v D+f G+GG i+ a+ v++ di+ +++ k + +N +
tr|H2R4E3|H2R4E3_PANTR 218 IVFDPFVGTGGLLIACAHFGAYVYGTDIDYNTVhglgKATRKNQK 262
789**************************9998333334555555 PP
>> tr|H2Q1P7|H2Q1P7_PANTR NOP2/Sun RNA methyltransferase family member 6 OS=Pan troglodytes OX=9598 GN=NSUN6 PE=3 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 12.3 0.0 5.8e-05 0.13 3 48 .. 232 280 .. 230 340 .. 0.85
Alignments for each domain:
== domain 1 score: 12.3 bits; conditional E-value: 5.8e-05
Methyltransf_15 3 vvlDlfgGaGGnviqfanv...fekviaidinlsrlklaqhNaevYgvs 48
+lDl++ GG++ ++a +via+d+ +++++ +++Na + g +
tr|H2Q1P7|H2Q1P7_PANTR 232 KILDLCAAPGGKTTHIAALmhdQGEVIALDKIFNKVEKIKQNALLLGLN 280
79**************998444347******************888664 PP
>> tr|H2QHS9|H2QHS9_PANTR THUMP domain containing 2 OS=Pan troglodytes OX=9598 GN=THUMPD2 PE=2 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? -2.0 0.0 1.4 3.3e+03 45 69 .. 45 68 .. 38 77 .. 0.82
2 ? 10.3 0.0 0.00024 0.56 3 82 .. 301 378 .. 299 400 .. 0.84
Alignments for each domain:
== domain 1 score: -2.0 bits; conditional E-value: 1.4
Methyltransf_15 45 Ygvsdkvtlvlgdvfellaklklee 69
Y +s kv++ ++ ++l+klk++e
tr|H2QHS9|H2QHS9_PANTR 45 Y-ISGKVFFTTCSDLNMLKKLKSAE 68
4.78899999999999999999876 PP
== domain 2 score: 10.3 bits; conditional E-value: 0.00024
Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekvi..aidinlsrlklaqhNaevYgvsdkvtlvlgdvfellaklkleeikvdlvflSpPwG 82
vlD+++G G + a++++ v+ + d++ s+l + N ++ g +dk++l + v el +e++ d+++ +P G
tr|H2QHS9|H2QHS9_PANTR 301 FVLDPMCGLGTILLEAAKEWPDVYyvGADVSDSQLLGTWDNLKAAGLEDKIELLKISVIELPL--PSESV--DIIISDIPFG 378
68********************984467889999999****************9999888643..34444..7777777776 PP
>> tr|A0A2J8JEW0|A0A2J8JEW0_PANTR NOP2 isoform 16 OS=Pan troglodytes OX=9598 GN=NOP2 PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 11.5 0.0 0.0001 0.24 2 52 .. 419 472 .. 418 504 .. 0.87
Alignments for each domain:
== domain 1 score: 11.5 bits; conditional E-value: 0.0001
Methyltransf_15 2 evvlDlfgGaGGnviqfanvfek...viaidinlsrlklaqhNaevYgvsdkvt 52
e +lD+++ GG++ +a+ ++ + a d n +rlk + N + gv + +
tr|A0A2J8JEW0|A0A2J8JEW0_PANTR 419 ERILDMCCAPGGKTSYMAQLMKNtgvILANDANAERLKSVVGNLHRLGVTNTII 472
579***************996652226788***************999988875 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (165 nodes)
Target sequences: 23008 (11942255 residues searched)
Passed MSV filter: 620 (0.0269471); expected 460.2 (0.02)
Passed bias filter: 513 (0.0222966); expected 460.2 (0.02)
Passed Vit filter: 52 (0.00226008); expected 23.0 (0.001)
Passed Fwd filter: 10 (0.000434631); expected 0.2 (1e-05)
Initial search space (Z): 23008 [actual number of targets]
Domain search space (domZ): 10 [number of targets reported over threshold]
# CPU time: 0.18u 0.01s 00:00:00.19 Elapsed: 00:00:00.08
# Mc/sec: 24630.90
//
[ok]