# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/Methyltransf_15.hmm.txt
# target sequence database:        proteomes/Strongylocentrotus_purpuratus.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       Methyltransf_15  [M=165]
Accession:   PF09445.9
Description: RNA cap guanine-N2 methyltransferase
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
    1.7e-39  135.8   0.0    3.1e-39  135.0   0.0    1.4  1  tr|W4Y0S2|W4Y0S2_STRPU  Uncharacterized protein OS=Strongyloc
      2e-08   34.8   0.3    6.7e-08   33.1   0.1    1.9  2  tr|W4YBQ4|W4YBQ4_STRPU  Uncharacterized protein OS=Strongyloc
    2.4e-05   24.8   0.1    4.3e-05   23.9   0.1    1.5  1  tr|W4YQG0|W4YQG0_STRPU  Uncharacterized protein OS=Strongyloc
     0.0032   17.9   0.0     0.0048   17.3   0.0    1.3  1  tr|W4Y3I4|W4Y3I4_STRPU  Uncharacterized protein OS=Strongyloc
  ------ inclusion threshold ------
       0.02   15.3   0.1       0.03   14.7   0.1    1.2  1  tr|W4Z4G0|W4Z4G0_STRPU  Ubiquinone biosynthesis O-methyltrans
      0.032   14.6   0.1      0.052   13.9   0.1    1.3  1  tr|W4XJA0|W4XJA0_STRPU  Uncharacterized protein OS=Strongyloc
      0.072   13.5   0.0        0.9    9.9   0.0    2.4  2  tr|W4YER5|W4YER5_STRPU  tRNA (guanine(37)-N1)-methyltransfera
      0.073   13.4   0.0       0.13   12.6   0.0    1.3  1  tr|W4YGN5|W4YGN5_STRPU  Uncharacterized protein OS=Strongyloc
      0.081   13.3   0.0       0.16   12.3   0.0    1.4  1  tr|W4YT52|W4YT52_STRPU  Uncharacterized protein OS=Strongyloc
       0.17   12.2   0.1       0.47   10.8   0.0    1.7  2  tr|W4XRJ4|W4XRJ4_STRPU  Uncharacterized protein OS=Strongyloc


Domain annotation for each sequence (and alignments):
>> tr|W4Y0S2|W4Y0S2_STRPU  Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  135.0   0.0   1.1e-42   3.1e-39       2     164 ..    1294    1446 ..    1293    1447 .. 0.95

  Alignments for each domain:
  == domain 1  score: 135.0 bits;  conditional E-value: 1.1e-42
         Methyltransf_15    2 evvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfellaklkleeikvdlvflSpPwGGpsY 86  
                               +++D+f+G+GGn+iqfa + e+v+a+di++ +++la hNa vYgv+d++++++gd+f++   l     k d+vflSpPwGGp+Y
  tr|W4Y0S2|W4Y0S2_STRPU 1294 DLIVDAFCGSGGNAIQFAFTCERVVAVDIDPAKIELARHNATVYGVEDRIEFIVGDFFKVADYL-----KADVVFLSPPWGGPKY 1373
                              579*******************************************************998875.....45899*********** PP

         Methyltransf_15   87 kkkekfdlekkleplklekllkesvklskniilfLPrnsdlkqlaaltaevlenaskvkvvklkenglvkallaylge 164 
                               + e+fdl  ++ ++    +++++  +s+ni +f Prn++++qla+l    +++  ++++ +   n  +k+++ay+ge
  tr|W4Y0S2|W4Y0S2_STRPU 1374 LNAEVFDL-FSMMDIDTAAMFEKARCISENIGFFAPRNANVEQLASL----AGPGGRMEIEQNFLNKKIKTITAYYGE 1446
                              ********.89999******************************998....8999********************986 PP

>> tr|W4YBQ4|W4YBQ4_STRPU  Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=3 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.0       1.1   3.1e+03     116     150 ..     146     180 ..     137     200 .. 0.71
   2 !   33.1   0.1   2.3e-11   6.7e-08       2      84 ..     518     601 ..     517     644 .. 0.87

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 1.1
         Methyltransf_15 116 niilfLPrnsdlkqlaaltaevlenaskvkvvklk 150
                              ++  LP     +ql++++  +  + +k+k ++ k
  tr|W4YBQ4|W4YBQ4_STRPU 146 IMLRNLPTRFGFQQLRKMLSGLNLKPKKIKSLNQK 180
                             4556799999999*****99999999999844433 PP

  == domain 2  score: 33.1 bits;  conditional E-value: 2.3e-11
         Methyltransf_15   2 evvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfellaklkleei.kvdlv.flSpPwGGp 84 
                             +++lD+++G+G   i +a+  ekvi++++n++ ++ a++Na + gv d+vt+ +g+ ++ll  ++ +     d+v ++ pP  G 
  tr|W4YBQ4|W4YBQ4_STRPU 518 TTLLDICCGTGTIGISLAKRVEKVIGVEMNEQAIEDAKENAAINGV-DNVTFHCGKAEDLLPGITNRLHsCLDVVgIVDPPRAGL 601
                             689*****************************************98.68**********99887655433488885567777775 PP

>> tr|W4YQG0|W4YQG0_STRPU  Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.9   0.1   1.5e-08   4.3e-05       4     110 ..      52     158 ..      49     209 .. 0.80

  Alignments for each domain:
  == domain 1  score: 23.9 bits;  conditional E-value: 1.5e-08
         Methyltransf_15   4 vlDlfgGaGGnviqfanv.fekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfellaklkleeikvdlvflSpPwGGpsYkk. 88 
                             + Dl +G+G  +i  a+      i+ di+++ l+++q+N+e ++    v++v+ d++++ a   +++   d v++ pP G  + k  
  tr|W4YQG0|W4YQG0_STRPU  52 IADLGCGCGMLSIGAAMLdAGLCIGFDIDQDALEICQRNCEEFE-LPCVDTVQSDLTKMEAGPWSKKF--DTVIMNPPFGTKHNKGi 135
                             67999********9998865579********************5.678**********9999988888..*********96544321 PP

         Methyltransf_15  89 .kekfdlekkleplklekllkes 110
                               +  +l  ++   +++ l k+s
  tr|W4YQG0|W4YQG0_STRPU 136 dLQFVQLGLEMATKSVYSLHKTS 158
                             02222333355566666666654 PP

>> tr|W4Y3I4|W4Y3I4_STRPU  Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.3   0.0   1.7e-06    0.0048       3      78 ..     111     184 ..     109     195 .. 0.84

  Alignments for each domain:
  == domain 1  score: 17.3 bits;  conditional E-value: 1.7e-06
         Methyltransf_15   3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevY.gvsdkvtlvlgdvfellaklkleeikvdlvflS 78 
                             +++D+ +G+G  +  +a+   +vi++d  ++++++aqh       +  +v++++g  ++l+++   e+  +d +++S
  tr|W4Y3I4|W4Y3I4_STRPU 111 TIVDVGCGGGILAEPLARLGATVIGVDATPENIEVAQHHVSHDpTIRGNVKYICGTAEDLVRTE-DEA--FDALVCS 184
                             689**********************************99877525799********99998762.222..4555555 PP

>> tr|W4Z4G0|W4Z4G0_STRPU  Ubiquinone biosynthesis O-methyltransferase, mitochondrial OS=Strongylocentrotus purpuratus O
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.7   0.1     1e-05      0.03       3      64 ..     157     219 ..     155     251 .. 0.83

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 1e-05
         Methyltransf_15   3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevY.gvsdkvtlvlgdvfellak 64 
                             +++D+ +G+G  +  +a+   +vi++d  ++++++aqh       +  +v++++g  ++l+ +
  tr|W4Z4G0|W4Z4G0_STRPU 157 TIVDVGCGGGILAEPLARLGATVIGVDATPENIEVAQHHVSHDpTIRGNVKYICGTAEDLVCT 219
                             689**********************************99876525799******999987643 PP

>> tr|W4XJA0|W4XJA0_STRPU  Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   0.1   1.8e-05     0.052       3      59 ..     237     291 ..     236     330 .. 0.71

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 1.8e-05
         Methyltransf_15   3 vvlDlfgGaGGnviqfanvfe..kviaidinlsrlklaqhNaevYgvsdkvtlvlgdvf 59 
                             +vlD+ +G GG +i +a++++  + i+idi  + +++    a+ Y ++ +v+ v  +++
  tr|W4XJA0|W4XJA0_STRPU 237 TVLDVGCGEGGASILMAKQYPnsRFIGIDICSYAIQQ----AKGYAIDAEVENVDFQIM 291
                             58*****************862256777776666655....555666666655554444 PP

>> tr|W4YER5|W4YER5_STRPU  tRNA (guanine(37)-N1)-methyltransferase OS=Strongylocentrotus purpuratus OX=7668 PE=3 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.9   0.0   0.00031       0.9       3      57 ..     240     294 ..     238     333 .. 0.83
   2 ?    0.6   0.0      0.23   6.6e+02       6      54 ..     419     467 ..     418     504 .. 0.80

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 0.00031
         Methyltransf_15   3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvtlvlgd 57 
                             vv D+f+G G  +i  a+  ++v+a d n++  +  + Na+    s++++    d
  tr|W4YER5|W4YER5_STRPU 240 VVYDMFAGVGPFAIPAAKKGCEVHANDLNPESFRWLEVNAKQNKLSSRLKASNLD 294
                             688*************************************999888888766555 PP

  == domain 2  score: 0.6 bits;  conditional E-value: 0.23
         Methyltransf_15   6 DlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvtlv 54 
                             D+ gG G  +   a+  ++v+a d n++  +  + Na+    s++++  
  tr|W4YER5|W4YER5_STRPU 419 DIGGGVGPFATPAAKKGCEVHANDLNPESFRWLELNAKQNKLSSRLKAS 467
                             555677777777888999**************99999988888887765 PP

>> tr|W4YGN5|W4YGN5_STRPU  Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.0   4.6e-05      0.13       3      51 ..      44      92 ..      43      96 .. 0.89

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 4.6e-05
         Methyltransf_15  3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvsdkv 51
                            +v+D+ +G+G  +  +a+ f++  + di++ +++ a++  ++  v+  +
  tr|W4YGN5|W4YGN5_STRPU 44 LVVDVGCGSGQFTQSLARHFDRALGFDISEAQIEEAKKHNQFSHVEYSI 92
                            589*******************************999888887777665 PP

>> tr|W4YT52|W4YT52_STRPU  Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   5.6e-05      0.16      22      80 ..     269     329 ..     258     331 .. 0.79

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 5.6e-05
         Methyltransf_15  22 fekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfe...llaklkleeikvdlvflSpP 80 
                               +v aid +++ + l+q Na   gvs+++ + +  +++   l  + k + +++d+++  pP
  tr|W4YT52|W4YT52_STRPU 269 LAHVTAIDASRDAVMLTQDNASRLGVSNRLSVHHTALTDespLRIHSKYG-TRYDVIVSNPP 329
                             4589***************************9999888755333444444.469***99999 PP

>> tr|W4XRJ4|W4XRJ4_STRPU  Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=3 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.0   0.00016      0.47       2      40 ..      43      81 ..      42     102 .. 0.91
   2 ?   -2.0   0.0       1.4   4.1e+03      41      80 ..     174     214 ..     171     235 .. 0.74

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.00016
         Methyltransf_15  2 evvlDlfgGaGGnviqfanvfekviaidinlsrlklaqh 40
                            + vlD+ +G+GG++  + +   +v + d+ +  lk+a +
  tr|W4XRJ4|W4XRJ4_STRPU 43 RRVLDAACGTGGDSLFLLKHGYEVSSSDSAEAMLKQARK 81
                            789**************99999************99976 PP

  == domain 2  score: -2.0 bits;  conditional E-value: 1.4
         Methyltransf_15  41 NaevYgvsdkvtlvlgdvfellaklkleeikvdlvf.lSpP 80 
                             N +vY  +d ++ +  ++ +   k  + +i++d+++  S P
  tr|W4XRJ4|W4XRJ4_STRPU 174 NKHVYFKEDTINKISSEIVKSPGKQDFVNITFDMIVdGSAP 214
                             66777778888888888888777777778878877634555 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (165 nodes)
Target sequences:                        28594  (14266044 residues searched)
Passed MSV filter:                       735  (0.0257047); expected 571.9 (0.02)
Passed bias filter:                      592  (0.0207036); expected 571.9 (0.02)
Passed Vit filter:                        58  (0.0020284); expected 28.6 (0.001)
Passed Fwd filter:                        10  (0.000349724); expected 0.3 (1e-05)
Initial search space (Z):              28594  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 0.19u 0.01s 00:00:00.20 Elapsed: 00:00:00.08
# Mc/sec: 29423.72
//
[ok]