# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/Methyltransf_15.hmm.txt # target sequence database: proteomes/Trichomonas_vaginalis.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: Methyltransf_15 [M=165] Accession: PF09445.9 Description: RNA cap guanine-N2 methyltransferase Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.4e-24 88.1 0.1 2e-24 87.6 0.1 1.2 1 tr|A2DM16|A2DM16_TRIVA MGC80481 protein, putative OS=Trichom 1.9e-06 29.1 0.0 3.8e-06 28.2 0.0 1.6 1 tr|A2FNS0|A2FNS0_TRIVA Uncharacterized protein OS=Trichomona 5.3e-05 24.4 0.3 9.6e-05 23.6 0.3 1.4 1 sp|A2E5K9|TRM5_TRIVA tRNA (guanine(37)-N1)-methyltransfera 9e-05 23.7 0.0 0.00019 22.6 0.0 1.6 1 tr|A2ELU0|A2ELU0_TRIVA Uncharacterized protein OS=Trichomona 0.00036 21.7 0.0 0.0069 17.6 0.0 2.4 2 tr|A2E827|A2E827_TRIVA Uncharacterized protein OS=Trichomona ------ inclusion threshold ------ 0.012 16.8 0.0 0.019 16.1 0.0 1.4 1 tr|A2DMU5|A2DMU5_TRIVA Methyltransferase, putative OS=Tricho 0.067 14.3 0.1 0.15 13.2 0.0 1.5 2 tr|A2FGC5|A2FGC5_TRIVA Uncharacterized protein OS=Trichomona 0.15 13.2 0.1 0.26 12.4 0.1 1.5 1 tr|A2F7I7|A2F7I7_TRIVA NOL1/NOP2/sun family putative RNA met 0.17 13.0 0.0 0.31 12.2 0.0 1.4 1 tr|A2ESN8|A2ESN8_TRIVA tRNA (guanine-N(7)-)-methyltransferas 0.21 12.8 0.1 0.4 11.8 0.1 1.4 1 tr|A2FQY9|A2FQY9_TRIVA tRNA (guanine(26)-N(2))-dimethyltrans 0.31 12.2 0.0 0.48 11.6 0.0 1.2 1 tr|A2FJV7|A2FJV7_TRIVA Proteasome endopeptidase complex OS=T Domain annotation for each sequence (and alignments): >> tr|A2DM16|A2DM16_TRIVA MGC80481 protein, putative OS=Trichomonas vaginalis OX=5722 GN=TVAG_463050 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 87.6 0.1 4.3e-28 2e-24 3 129 .. 117 241 .. 115 273 .. 0.80 Alignments for each domain: == domain 1 score: 87.6 bits; conditional E-value: 4.3e-28 Methyltransf_15 3 vvlDlfgGaGGnviqfanv....fekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfellaklkleeikvdlvflSpPwGGps 85 +++D+++G GGn+ +fa f vi+id++ r+ +a++N +v v++ ++v+gdv + l++ + ++ +vf+SpPwGGp tr|A2DM16|A2DM16_TRIVA 117 IIIDACCGVGGNTTAFAACiqdsF--VIGIDTSAIRIVCAKKNSKVCKVDQATDFVKGDVIKFLNTQHNSAR---FVFCSPPWGGPG 198 89***************9855444..**************************************99777666...************ PP Methyltransf_15 86 YkkkekfdlekkleplklekllkesvklskniilfLPrnsdlkq 129 Y+ + d+ ++e l+ + + k+ v+ ++ilfLPr+ d ++ tr|A2DM16|A2DM16_TRIVA 199 YTVESLSDFPFDIESLS-KAVSKACVNNEMRLILFLPREFDPEK 241 *****999944444433.3344557888899*******988665 PP >> tr|A2FNS0|A2FNS0_TRIVA Uncharacterized protein OS=Trichomonas vaginalis OX=5722 GN=TVAG_137180 PE=3 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.2 0.0 8.4e-10 3.8e-06 2 56 .. 350 404 .. 349 496 .. 0.88 Alignments for each domain: == domain 1 score: 28.2 bits; conditional E-value: 8.4e-10 Methyltransf_15 2 evvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvtlvlg 56 +v++D ++G+G n+ + ++ ++ i+id+++s+++ +q+Nae ++++ +++ g tr|A2FNS0|A2FNS0_TRIVA 350 TVLVDFCCGTGVNCLSLSKSVKRCIGIDSSESNIATSQRNAEENQIKNAYFVIGG 404 5799**************************************9998887777655 PP >> sp|A2E5K9|TRM5_TRIVA tRNA (guanine(37)-N1)-methyltransferase OS=Trichomonas vaginalis OX=5722 GN=TVAG_038970 PE=3 SV # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.6 0.3 2.1e-08 9.6e-05 3 86 .. 208 290 .. 206 295 .. 0.88 Alignments for each domain: == domain 1 score: 23.6 bits; conditional E-value: 2.1e-08 Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfellaklkleeikvdlvflSpPwGGpsY 86 +v D+++G G ++ a+ ++v a d n++ + ++N+++ gvs++v++ d e ++k ++++ d +++ P +++ sp|A2E5K9|TRM5_TRIVA 208 LVCDAMCGIGPFAVRAAKKGCRVRANDLNPDSYYWLKENCKINGVSENVECFNMDAREFIRK-QFDNGGCDYIVMNLPGTAVEF 290 578*******************************************************9987.444444699999999766665 PP >> tr|A2ELU0|A2ELU0_TRIVA Uncharacterized protein OS=Trichomonas vaginalis OX=5722 GN=TVAG_151750 PE=3 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.6 0.0 4.1e-08 0.00019 2 84 .. 377 461 .. 376 498 .. 0.77 Alignments for each domain: == domain 1 score: 22.6 bits; conditional E-value: 4.1e-08 Methyltransf_15 2 evvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfe....llaklkleeikvdlvflSpPwGGp 84 +v++D+++G+G +a+ +kvi+idi+++ ++ a++Na ++ + +++ + ++ +l +++ e + +v++ pP G tr|A2ELU0|A2ELU0_TRIVA 377 TVLIDVCCGTGVIGLSMAKKAKKVIGIDIEKDAIEDAKKNATKNKIK-NAEFIAAPAQDvlpgILDQCEAEGS-RVVVIVDPPRDGL 461 689**************************************988664.4455554444433344555555444.5566677776665 PP >> tr|A2E827|A2E827_TRIVA Uncharacterized protein OS=Trichomonas vaginalis OX=5722 GN=TVAG_498390 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.6 0.0 1.5e-06 0.0069 33 151 .. 92 266 .. 57 280 .. 0.77 2 ? 1.4 0.0 0.14 6.5e+02 110 131 .. 355 376 .. 319 407 .. 0.64 Alignments for each domain: == domain 1 score: 17.6 bits; conditional E-value: 1.5e-06 Methyltransf_15 33 srlklaqhNaevYgv.sdkvtlvlgdvfe......................................................llak 64 s+lk+ +Nae ++++ lv+g + +l++ tr|A2E827|A2E827_TRIVA 92 SQLKCHGKNAEERWCeARRIALVQGHILFsnealltfppfyfngrgrclpfrqqrnimsgepfltrrsldeiaydatnddeiiILSS 178 456666666654322255666666665446888888888888888888888888888888888888888889999999999989999 PP Methyltransf_15 65 lkleeikvdlvflSpPwGGpsYkkkekfdlekkleplklekllkesvklskniilfLPrnsdlkql....aaltaevlenaskvkvv 147 ++e+ ++d+++ S p Y+ + +d++k+ + + +e+l k ++k+ kni+ LP+++ + ++ ++ + +++ ++k++ + tr|A2E827|A2E827_TRIVA 179 GTEENFNYDFIVSSLL---PLYTTLNRLDVNKTKKLYVMENLSKFDTKIFKNILKALPQKVPVSDVpallKNAVIGLVKGDKKCEPS 262 999999********84...78*********999999***************************998444444455677888888766 PP Methyltransf_15 148 klke 151 + ++ tr|A2E827|A2E827_TRIVA 263 RHDN 266 6555 PP == domain 2 score: 1.4 bits; conditional E-value: 0.14 Methyltransf_15 110 svklskniilfLPrnsdlkqla 131 + + ++++lf+P+ns ++a tr|A2E827|A2E827_TRIVA 355 TPNHGSELMLFMPKNSVFLDVA 376 4455567899****99887774 PP >> tr|A2DMU5|A2DMU5_TRIVA Methyltransferase, putative OS=Trichomonas vaginalis OX=5722 GN=TVAG_254280 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 16.1 0.0 4.1e-06 0.019 3 85 .. 51 131 .. 49 170 .. 0.75 Alignments for each domain: == domain 1 score: 16.1 bits; conditional E-value: 4.1e-06 Methyltransf_15 3 vvlDlfgGaGGnviqfanv.fekviaidinlsrlklaqhNaevYgvsd..kvtlvlgdvfellaklkleeikvdlvflSpPwGGps 85 +v Dl +G+G +i+ + ++v++ d ++ ++ a++N + + ++ +++ +dv++l + k +d v++ pP G + tr|A2DMU5|A2DMU5_TRIVA 51 IVADLGCGCGILSIACLVMgAKEVHSFDLDPVSIEAAKRNLDLLEFDEppPIFFHECDVTKLGDEQK-----FDTVVMNPPFGTRN 131 788999****9999877664789*******************987755227*******998877643.....47789****99654 PP >> tr|A2FGC5|A2FGC5_TRIVA Uncharacterized protein OS=Trichomonas vaginalis OX=5722 GN=TVAG_309480 PE=3 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.7 0.0 1.2 5.7e+03 112 153 .. 28 57 .. 11 69 .. 0.53 2 ? 13.2 0.0 3.2e-05 0.15 5 63 .. 65 126 .. 61 146 .. 0.86 Alignments for each domain: == domain 1 score: -1.7 bits; conditional E-value: 1.2 Methyltransf_15 112 klskniilfLPrnsdlkqlaaltaevlenaskvkvvklkeng 153 ++++n i++ P + ++l+ +v+++ n+ tr|A2FGC5|A2FGC5_TRIVA 28 EYTENEIFYNPVQQFNRDLTC------------AVIQAYRNS 57 344444444444444444443............333333333 PP == domain 2 score: 13.2 bits; conditional E-value: 3.2e-05 Methyltransf_15 5 lDlfgGaGGnviqfanv...fekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfella 63 +f+ +G +i +a++ +k+ia d ++ ++++++N + vs+ vt +gd e + tr|A2FGC5|A2FGC5_TRIVA 65 FEAFAASGLRSIRYAKEvsgVKKIIANDLDQAAVEIIKRNILINKVSNLVTASQGDAREKML 126 5789999999999999988889**********************************988543 PP >> tr|A2F7I7|A2F7I7_TRIVA NOL1/NOP2/sun family putative RNA methylase containing protein OS=Trichomonas vaginalis OX=57 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.1 5.7e-05 0.26 4 53 .. 226 278 .. 224 375 .. 0.84 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 5.7e-05 Methyltransf_15 4 vlDlfgGaGGnviqfanv...fekviaidinlsrlklaqhNaevYgvsdkvtl 53 lD+++ GG++ ++a+ +ia din++r + N + gv + + + tr|A2F7I7|A2F7I7_TRIVA 226 TLDMCAAPGGKTTHMAQLmknQGVIIANDINRTRAQALIANIHRLGVTNTIVV 278 69**************9944333599*********************988865 PP >> tr|A2ESN8|A2ESN8_TRIVA tRNA (guanine-N(7)-)-methyltransferase OS=Trichomonas vaginalis OX=5722 GN=TVAG_069970 PE=3 S # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.0 6.8e-05 0.31 3 76 .. 62 139 .. 60 154 .. 0.78 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 6.8e-05 Methyltransf_15 3 vvlDlfgGaGGnviqfanvfek..viaidinlsrlklaqhNaevYgvsdkvtlvlgdvfe....llaklkleeikvdlvf 76 ++lD+ +G GG + ++ +f++ ++a++i + +++ ++Y + ++ ++ + l++ l+ ++i + +f tr|A2ESN8|A2ESN8_TRIVA 62 TMLDIGCGYGGMTFALSTEFPQnlIFALEIRSQVTTYVEKKIQAYHAQGLALNIQVQWANtmrtLMRYLRAHTI--EKIF 139 589****************9755599*******************99988888888888844444444444444..4444 PP >> tr|A2FQY9|A2FQY9_TRIVA tRNA (guanine(26)-N(2))-dimethyltransferase OS=Trichomonas vaginalis OX=5722 GN=TVAG_439220 P # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.8 0.1 8.7e-05 0.4 6 72 .. 60 129 .. 56 135 .. 0.89 Alignments for each domain: == domain 1 score: 11.8 bits; conditional E-value: 8.7e-05 Methyltransf_15 6 DlfgGaGGnviqfanv...fekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfellaklkleeikv 72 +f+ +G +i +a++ f+++ a di+++ ++ +N ++ v++ v+ lgd ++++++ k e + tr|A2FQY9|A2FQY9_TRIVA 60 EAFAATGLRSIRYAREvtgFNSITANDIDKNAGSIIDRNIQLNKVDNIVKSSLGDANKVMNSHKGEYQII 129 6799999999999999999***************************************999988766555 PP >> tr|A2FJV7|A2FJV7_TRIVA Proteasome endopeptidase complex OS=Trichomonas vaginalis OX=5722 GN=TVAG_103780 PE=3 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.0 0.00011 0.48 12 73 .. 30 96 .. 26 101 .. 0.85 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 0.00011 Methyltransf_15 12 GGnviqfanvfekviaidinlsr.lklaqhNaevYgvsdkvtlvlgdvfe....llaklkleeikvd 73 GG+++ ++ via+++++s l N +v ++d+v +v+ v++ +l++l++++ik++ tr|A2FJV7|A2FJV7_TRIVA 30 GGQCVGVKAKNGAVIACESKPSSpLVEKVTNLKVQKINDNVGIVYSGVNTdfhvILKSLRKASIKYS 96 9********999******998753888899***********99987666655559999999998876 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (165 nodes) Target sequences: 50190 (17055200 residues searched) Passed MSV filter: 2070 (0.0412433); expected 1003.8 (0.02) Passed bias filter: 1034 (0.0206017); expected 1003.8 (0.02) Passed Vit filter: 68 (0.00135485); expected 50.2 (0.001) Passed Fwd filter: 12 (0.000239091); expected 0.5 (1e-05) Initial search space (Z): 50190 [actual number of targets] Domain search space (domZ): 11 [number of targets reported over threshold] # CPU time: 0.28u 0.01s 00:00:00.29 Elapsed: 00:00:00.11 # Mc/sec: 25582.80 // [ok]