# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/Methyltransf_15.hmm.txt
# target sequence database: proteomes/Trichomonas_vaginalis.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: Methyltransf_15 [M=165]
Accession: PF09445.9
Description: RNA cap guanine-N2 methyltransferase
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
1.4e-24 88.1 0.1 2e-24 87.6 0.1 1.2 1 tr|A2DM16|A2DM16_TRIVA MGC80481 protein, putative OS=Trichom
1.9e-06 29.1 0.0 3.8e-06 28.2 0.0 1.6 1 tr|A2FNS0|A2FNS0_TRIVA Uncharacterized protein OS=Trichomona
5.3e-05 24.4 0.3 9.6e-05 23.6 0.3 1.4 1 sp|A2E5K9|TRM5_TRIVA tRNA (guanine(37)-N1)-methyltransfera
9e-05 23.7 0.0 0.00019 22.6 0.0 1.6 1 tr|A2ELU0|A2ELU0_TRIVA Uncharacterized protein OS=Trichomona
0.00036 21.7 0.0 0.0069 17.6 0.0 2.4 2 tr|A2E827|A2E827_TRIVA Uncharacterized protein OS=Trichomona
------ inclusion threshold ------
0.012 16.8 0.0 0.019 16.1 0.0 1.4 1 tr|A2DMU5|A2DMU5_TRIVA Methyltransferase, putative OS=Tricho
0.067 14.3 0.1 0.15 13.2 0.0 1.5 2 tr|A2FGC5|A2FGC5_TRIVA Uncharacterized protein OS=Trichomona
0.15 13.2 0.1 0.26 12.4 0.1 1.5 1 tr|A2F7I7|A2F7I7_TRIVA NOL1/NOP2/sun family putative RNA met
0.17 13.0 0.0 0.31 12.2 0.0 1.4 1 tr|A2ESN8|A2ESN8_TRIVA tRNA (guanine-N(7)-)-methyltransferas
0.21 12.8 0.1 0.4 11.8 0.1 1.4 1 tr|A2FQY9|A2FQY9_TRIVA tRNA (guanine(26)-N(2))-dimethyltrans
0.31 12.2 0.0 0.48 11.6 0.0 1.2 1 tr|A2FJV7|A2FJV7_TRIVA Proteasome endopeptidase complex OS=T
Domain annotation for each sequence (and alignments):
>> tr|A2DM16|A2DM16_TRIVA MGC80481 protein, putative OS=Trichomonas vaginalis OX=5722 GN=TVAG_463050 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 87.6 0.1 4.3e-28 2e-24 3 129 .. 117 241 .. 115 273 .. 0.80
Alignments for each domain:
== domain 1 score: 87.6 bits; conditional E-value: 4.3e-28
Methyltransf_15 3 vvlDlfgGaGGnviqfanv....fekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfellaklkleeikvdlvflSpPwGGps 85
+++D+++G GGn+ +fa f vi+id++ r+ +a++N +v v++ ++v+gdv + l++ + ++ +vf+SpPwGGp
tr|A2DM16|A2DM16_TRIVA 117 IIIDACCGVGGNTTAFAACiqdsF--VIGIDTSAIRIVCAKKNSKVCKVDQATDFVKGDVIKFLNTQHNSAR---FVFCSPPWGGPG 198
89***************9855444..**************************************99777666...************ PP
Methyltransf_15 86 YkkkekfdlekkleplklekllkesvklskniilfLPrnsdlkq 129
Y+ + d+ ++e l+ + + k+ v+ ++ilfLPr+ d ++
tr|A2DM16|A2DM16_TRIVA 199 YTVESLSDFPFDIESLS-KAVSKACVNNEMRLILFLPREFDPEK 241
*****999944444433.3344557888899*******988665 PP
>> tr|A2FNS0|A2FNS0_TRIVA Uncharacterized protein OS=Trichomonas vaginalis OX=5722 GN=TVAG_137180 PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 28.2 0.0 8.4e-10 3.8e-06 2 56 .. 350 404 .. 349 496 .. 0.88
Alignments for each domain:
== domain 1 score: 28.2 bits; conditional E-value: 8.4e-10
Methyltransf_15 2 evvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvtlvlg 56
+v++D ++G+G n+ + ++ ++ i+id+++s+++ +q+Nae ++++ +++ g
tr|A2FNS0|A2FNS0_TRIVA 350 TVLVDFCCGTGVNCLSLSKSVKRCIGIDSSESNIATSQRNAEENQIKNAYFVIGG 404
5799**************************************9998887777655 PP
>> sp|A2E5K9|TRM5_TRIVA tRNA (guanine(37)-N1)-methyltransferase OS=Trichomonas vaginalis OX=5722 GN=TVAG_038970 PE=3 SV
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 23.6 0.3 2.1e-08 9.6e-05 3 86 .. 208 290 .. 206 295 .. 0.88
Alignments for each domain:
== domain 1 score: 23.6 bits; conditional E-value: 2.1e-08
Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfellaklkleeikvdlvflSpPwGGpsY 86
+v D+++G G ++ a+ ++v a d n++ + ++N+++ gvs++v++ d e ++k ++++ d +++ P +++
sp|A2E5K9|TRM5_TRIVA 208 LVCDAMCGIGPFAVRAAKKGCRVRANDLNPDSYYWLKENCKINGVSENVECFNMDAREFIRK-QFDNGGCDYIVMNLPGTAVEF 290
578*******************************************************9987.444444699999999766665 PP
>> tr|A2ELU0|A2ELU0_TRIVA Uncharacterized protein OS=Trichomonas vaginalis OX=5722 GN=TVAG_151750 PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 22.6 0.0 4.1e-08 0.00019 2 84 .. 377 461 .. 376 498 .. 0.77
Alignments for each domain:
== domain 1 score: 22.6 bits; conditional E-value: 4.1e-08
Methyltransf_15 2 evvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfe....llaklkleeikvdlvflSpPwGGp 84
+v++D+++G+G +a+ +kvi+idi+++ ++ a++Na ++ + +++ + ++ +l +++ e + +v++ pP G
tr|A2ELU0|A2ELU0_TRIVA 377 TVLIDVCCGTGVIGLSMAKKAKKVIGIDIEKDAIEDAKKNATKNKIK-NAEFIAAPAQDvlpgILDQCEAEGS-RVVVIVDPPRDGL 461
689**************************************988664.4455554444433344555555444.5566677776665 PP
>> tr|A2E827|A2E827_TRIVA Uncharacterized protein OS=Trichomonas vaginalis OX=5722 GN=TVAG_498390 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 17.6 0.0 1.5e-06 0.0069 33 151 .. 92 266 .. 57 280 .. 0.77
2 ? 1.4 0.0 0.14 6.5e+02 110 131 .. 355 376 .. 319 407 .. 0.64
Alignments for each domain:
== domain 1 score: 17.6 bits; conditional E-value: 1.5e-06
Methyltransf_15 33 srlklaqhNaevYgv.sdkvtlvlgdvfe......................................................llak 64
s+lk+ +Nae ++++ lv+g + +l++
tr|A2E827|A2E827_TRIVA 92 SQLKCHGKNAEERWCeARRIALVQGHILFsnealltfppfyfngrgrclpfrqqrnimsgepfltrrsldeiaydatnddeiiILSS 178
456666666654322255666666665446888888888888888888888888888888888888888889999999999989999 PP
Methyltransf_15 65 lkleeikvdlvflSpPwGGpsYkkkekfdlekkleplklekllkesvklskniilfLPrnsdlkql....aaltaevlenaskvkvv 147
++e+ ++d+++ S p Y+ + +d++k+ + + +e+l k ++k+ kni+ LP+++ + ++ ++ + +++ ++k++ +
tr|A2E827|A2E827_TRIVA 179 GTEENFNYDFIVSSLL---PLYTTLNRLDVNKTKKLYVMENLSKFDTKIFKNILKALPQKVPVSDVpallKNAVIGLVKGDKKCEPS 262
999999********84...78*********999999***************************998444444455677888888766 PP
Methyltransf_15 148 klke 151
+ ++
tr|A2E827|A2E827_TRIVA 263 RHDN 266
6555 PP
== domain 2 score: 1.4 bits; conditional E-value: 0.14
Methyltransf_15 110 svklskniilfLPrnsdlkqla 131
+ + ++++lf+P+ns ++a
tr|A2E827|A2E827_TRIVA 355 TPNHGSELMLFMPKNSVFLDVA 376
4455567899****99887774 PP
>> tr|A2DMU5|A2DMU5_TRIVA Methyltransferase, putative OS=Trichomonas vaginalis OX=5722 GN=TVAG_254280 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 16.1 0.0 4.1e-06 0.019 3 85 .. 51 131 .. 49 170 .. 0.75
Alignments for each domain:
== domain 1 score: 16.1 bits; conditional E-value: 4.1e-06
Methyltransf_15 3 vvlDlfgGaGGnviqfanv.fekviaidinlsrlklaqhNaevYgvsd..kvtlvlgdvfellaklkleeikvdlvflSpPwGGps 85
+v Dl +G+G +i+ + ++v++ d ++ ++ a++N + + ++ +++ +dv++l + k +d v++ pP G +
tr|A2DMU5|A2DMU5_TRIVA 51 IVADLGCGCGILSIACLVMgAKEVHSFDLDPVSIEAAKRNLDLLEFDEppPIFFHECDVTKLGDEQK-----FDTVVMNPPFGTRN 131
788999****9999877664789*******************987755227*******998877643.....47789****99654 PP
>> tr|A2FGC5|A2FGC5_TRIVA Uncharacterized protein OS=Trichomonas vaginalis OX=5722 GN=TVAG_309480 PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? -1.7 0.0 1.2 5.7e+03 112 153 .. 28 57 .. 11 69 .. 0.53
2 ? 13.2 0.0 3.2e-05 0.15 5 63 .. 65 126 .. 61 146 .. 0.86
Alignments for each domain:
== domain 1 score: -1.7 bits; conditional E-value: 1.2
Methyltransf_15 112 klskniilfLPrnsdlkqlaaltaevlenaskvkvvklkeng 153
++++n i++ P + ++l+ +v+++ n+
tr|A2FGC5|A2FGC5_TRIVA 28 EYTENEIFYNPVQQFNRDLTC------------AVIQAYRNS 57
344444444444444444443............333333333 PP
== domain 2 score: 13.2 bits; conditional E-value: 3.2e-05
Methyltransf_15 5 lDlfgGaGGnviqfanv...fekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfella 63
+f+ +G +i +a++ +k+ia d ++ ++++++N + vs+ vt +gd e +
tr|A2FGC5|A2FGC5_TRIVA 65 FEAFAASGLRSIRYAKEvsgVKKIIANDLDQAAVEIIKRNILINKVSNLVTASQGDAREKML 126
5789999999999999988889**********************************988543 PP
>> tr|A2F7I7|A2F7I7_TRIVA NOL1/NOP2/sun family putative RNA methylase containing protein OS=Trichomonas vaginalis OX=57
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 12.4 0.1 5.7e-05 0.26 4 53 .. 226 278 .. 224 375 .. 0.84
Alignments for each domain:
== domain 1 score: 12.4 bits; conditional E-value: 5.7e-05
Methyltransf_15 4 vlDlfgGaGGnviqfanv...fekviaidinlsrlklaqhNaevYgvsdkvtl 53
lD+++ GG++ ++a+ +ia din++r + N + gv + + +
tr|A2F7I7|A2F7I7_TRIVA 226 TLDMCAAPGGKTTHMAQLmknQGVIIANDINRTRAQALIANIHRLGVTNTIVV 278
69**************9944333599*********************988865 PP
>> tr|A2ESN8|A2ESN8_TRIVA tRNA (guanine-N(7)-)-methyltransferase OS=Trichomonas vaginalis OX=5722 GN=TVAG_069970 PE=3 S
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 12.2 0.0 6.8e-05 0.31 3 76 .. 62 139 .. 60 154 .. 0.78
Alignments for each domain:
== domain 1 score: 12.2 bits; conditional E-value: 6.8e-05
Methyltransf_15 3 vvlDlfgGaGGnviqfanvfek..viaidinlsrlklaqhNaevYgvsdkvtlvlgdvfe....llaklkleeikvdlvf 76
++lD+ +G GG + ++ +f++ ++a++i + +++ ++Y + ++ ++ + l++ l+ ++i + +f
tr|A2ESN8|A2ESN8_TRIVA 62 TMLDIGCGYGGMTFALSTEFPQnlIFALEIRSQVTTYVEKKIQAYHAQGLALNIQVQWANtmrtLMRYLRAHTI--EKIF 139
589****************9755599*******************99988888888888844444444444444..4444 PP
>> tr|A2FQY9|A2FQY9_TRIVA tRNA (guanine(26)-N(2))-dimethyltransferase OS=Trichomonas vaginalis OX=5722 GN=TVAG_439220 P
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 11.8 0.1 8.7e-05 0.4 6 72 .. 60 129 .. 56 135 .. 0.89
Alignments for each domain:
== domain 1 score: 11.8 bits; conditional E-value: 8.7e-05
Methyltransf_15 6 DlfgGaGGnviqfanv...fekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfellaklkleeikv 72
+f+ +G +i +a++ f+++ a di+++ ++ +N ++ v++ v+ lgd ++++++ k e +
tr|A2FQY9|A2FQY9_TRIVA 60 EAFAATGLRSIRYAREvtgFNSITANDIDKNAGSIIDRNIQLNKVDNIVKSSLGDANKVMNSHKGEYQII 129
6799999999999999999***************************************999988766555 PP
>> tr|A2FJV7|A2FJV7_TRIVA Proteasome endopeptidase complex OS=Trichomonas vaginalis OX=5722 GN=TVAG_103780 PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 11.6 0.0 0.00011 0.48 12 73 .. 30 96 .. 26 101 .. 0.85
Alignments for each domain:
== domain 1 score: 11.6 bits; conditional E-value: 0.00011
Methyltransf_15 12 GGnviqfanvfekviaidinlsr.lklaqhNaevYgvsdkvtlvlgdvfe....llaklkleeikvd 73
GG+++ ++ via+++++s l N +v ++d+v +v+ v++ +l++l++++ik++
tr|A2FJV7|A2FJV7_TRIVA 30 GGQCVGVKAKNGAVIACESKPSSpLVEKVTNLKVQKINDNVGIVYSGVNTdfhvILKSLRKASIKYS 96
9********999******998753888899***********99987666655559999999998876 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (165 nodes)
Target sequences: 50190 (17055200 residues searched)
Passed MSV filter: 2070 (0.0412433); expected 1003.8 (0.02)
Passed bias filter: 1034 (0.0206017); expected 1003.8 (0.02)
Passed Vit filter: 68 (0.00135485); expected 50.2 (0.001)
Passed Fwd filter: 12 (0.000239091); expected 0.5 (1e-05)
Initial search space (Z): 50190 [actual number of targets]
Domain search space (domZ): 11 [number of targets reported over threshold]
# CPU time: 0.28u 0.01s 00:00:00.29 Elapsed: 00:00:00.11
# Mc/sec: 25582.80
//
[ok]