# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/Methyltransf_15.hmm.txt # target sequence database: proteomes/Trichoplax_adhaerens.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: Methyltransf_15 [M=165] Accession: PF09445.9 Description: RNA cap guanine-N2 methyltransferase Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.8e-43 147.4 0.1 3.9e-43 146.4 0.1 1.6 1 tr|B3S2Q2|B3S2Q2_TRIAD Uncharacterized protein OS=Trichoplax 4.3e-07 29.2 0.4 1.4e-06 27.5 0.1 2.0 2 tr|B3S5B9|B3S5B9_TRIAD Uncharacterized protein OS=Trichoplax 0.00076 18.6 0.0 0.0011 18.0 0.0 1.3 1 tr|B3RQF2|B3RQF2_TRIAD Uncharacterized protein OS=Trichoplax 0.0013 17.8 0.1 0.0027 16.8 0.1 1.4 1 tr|B3S9Y1|B3S9Y1_TRIAD Ubiquinone biosynthesis O-methyltrans 0.0013 17.8 0.0 0.0024 17.0 0.0 1.4 1 tr|B3S3E8|B3S3E8_TRIAD Uncharacterized protein (Fragment) OS 0.006 15.7 0.0 0.011 14.8 0.0 1.5 1 tr|B3S9J8|B3S9J8_TRIAD Uncharacterized protein OS=Trichoplax ------ inclusion threshold ------ 0.016 14.3 0.0 0.032 13.3 0.0 1.4 1 tr|B3RUJ8|B3RUJ8_TRIAD Uncharacterized protein OS=Trichoplax 0.025 13.7 0.0 0.028 13.5 0.0 1.1 1 tr|B3RI96|B3RI96_TRIAD 40S ribosomal protein S23 OS=Trichopl 0.036 13.2 0.0 0.06 12.4 0.0 1.3 1 tr|B3S9J7|B3S9J7_TRIAD Uncharacterized protein OS=Trichoplax 0.047 12.8 0.1 0.19 10.8 0.1 2.0 2 tr|B3S2J4|B3S2J4_TRIAD Uncharacterized protein OS=Trichoplax 0.061 12.4 0.0 0.19 10.8 0.0 1.7 2 tr|B3S4V8|B3S4V8_TRIAD rRNA adenine N(6)-methyltransferase O 0.089 11.9 0.2 0.17 10.9 0.1 1.6 2 tr|B3RZP1|B3RZP1_TRIAD Uncharacterized protein OS=Trichoplax Domain annotation for each sequence (and alignments): >> tr|B3S2Q2|B3S2Q2_TRIAD Uncharacterized protein OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_58107 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 146.4 0.1 4.1e-46 3.9e-43 2 163 .. 563 714 .. 562 716 .. 0.95 Alignments for each domain: == domain 1 score: 146.4 bits; conditional E-value: 4.1e-46 Methyltransf_15 2 evvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfellaklkleeikvdlvflSpPwGGpsYkk 88 ++++D+f+G GGn+iqfa++ ++viaidi+++++k+a hNa++Y+v++k+++++gd+ +l +l k d+vflSpPwGGp Y k tr|B3S2Q2|B3S2Q2_TRIAD 563 SIIIDAFCGVGGNCIQFAKTCDHVIAIDIDPNKIKCARHNAKIYNVEHKIEFIVGDFLQLAPSL-----KADVVFLSPPWGGPTYLK 644 689********************************************************98875.....45999************* PP Methyltransf_15 89 kekfdlekkleplklekllkesvklskniilfLPrnsdlkqlaaltaevlenaskvkvvklkenglvkallaylg 163 ++fd+ k++ l ++++ es+++s+ni f Pr +++ ql++l ++ kv++ + ng vk+++ay+g tr|B3S2Q2|B3S2Q2_TRIAD 645 ADTFDI-KTMISLDGYRIFAESLSISRNIAYFVPRTANVSQLTQL----AGIGGKVEIEQNIINGKVKTVTAYYG 714 ******.9999*******************************988....788899******************98 PP >> tr|B3S5B9|B3S5B9_TRIAD Uncharacterized protein OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_59271 PE=3 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.4 0.0 2.2 2.1e+03 122 148 .. 304 330 .. 294 341 .. 0.75 2 ! 27.5 0.1 1.4e-09 1.4e-06 2 68 .. 401 466 .. 400 518 .. 0.82 Alignments for each domain: == domain 1 score: -2.4 bits; conditional E-value: 2.2 Methyltransf_15 122 Prnsdlkqlaaltaevlenaskvkvvk 148 P++ +ql++l e+ + +k++ + tr|B3S5B9|B3S5B9_TRIAD 304 PQDLSEDQLQSLKDEINRCLEKCDCQV 330 777778899999999999999988543 PP == domain 2 score: 27.5 bits; conditional E-value: 1.4e-09 Methyltransf_15 2 evvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfellaklkle 68 +vvlD+++G+G i +a+ ++vi+i++ ++ ++ a Nae+ ++ +++++++g+ ++ l +l + tr|B3S5B9|B3S5B9_TRIAD 401 TVVLDICCGTGTIGILMAKNVNRVIGIEMVEDAIEDARVNAELNDI-KNIEFICGKAEDKLPTLVDN 466 689*****************************************88.68*******99966554333 PP >> tr|B3RQF2|B3RQF2_TRIAD Uncharacterized protein OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_54966 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.0 0.0 1.2e-06 0.0011 3 85 .. 52 131 .. 50 167 .. 0.78 Alignments for each domain: == domain 1 score: 18.0 bits; conditional E-value: 1.2e-06 Methyltransf_15 3 vvlDlfgGaGGnviqfanv.fekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfellaklkleeikvdlvflSpPwGGps 85 +v Dl +G+G ++ a+ + +++idi+ + l +a +N e ++ ++v+l+++++ ++ ++ ++i +d v++ pP G + tr|B3RQF2|B3RQF2_TRIAD 52 LVCDLGCGCGVLSVGTAMLdASLIVGIDIDDDALMIARRNIEEFE-LENVQLIKANISDT--EFFGGKI-FDTVIMNPPFGTKD 131 6789*******99999988666799*******************5.689******99885..5556777.9*********9765 PP >> tr|B3S9Y1|B3S9Y1_TRIAD Ubiquinone biosynthesis O-methyltransferase, mitochondrial OS=Trichoplax adhaerens OX=10228 G # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.8 0.1 2.8e-06 0.0027 4 78 .. 109 182 .. 107 185 .. 0.83 Alignments for each domain: == domain 1 score: 16.8 bits; conditional E-value: 2.8e-06 Methyltransf_15 4 vlDlfgGaGGnviqfanvfekviaidinlsrlklaq.hNaevYgvsdkvtlvlgdvfellaklkleeikvdlvflS 78 +lD+ +G+G + +a+ +v +id + + +++a+ h ++ v+ +v + + +++l+++ + ++ +d v++S tr|B3S9Y1|B3S9Y1_TRIAD 109 ILDVGCGGGILCEPLARLGAQVTGIDASSEIINVAKaHASKCDRVAANVSYQCTTIEQLTTTENAQS--FDAVIAS 182 89*******************************9973666788899999997777777666544444..5999988 PP >> tr|B3S3E8|B3S3E8_TRIAD Uncharacterized protein (Fragment) OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_28123 PE=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.0 0.0 2.5e-06 0.0024 3 105 .. 206 321 .. 204 340 .. 0.67 Alignments for each domain: == domain 1 score: 17.0 bits; conditional E-value: 2.5e-06 Methyltransf_15 3 vvlDlfgGaGGnviqfanv...fekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfe..........llaklkleeikvdlvf 76 ++lD+++ GG++ ++a ++ia+d+++s+l+ ++ Nae + + +++ d ++ l+ ++ ++d ++ tr|B3S3E8|B3S3E8_TRIAD 206 TILDMCSAPGGKATHIATLmknKGTIIALDKSKSKLHKIKSNAERLNL-SCIEVFAFDSTKavadicqcqeGLRCPPFALESFDRIL 291 69*************9988443337******************98754.33444444444322222222224444344444679999 PP Methyltransf_15 77 lSpPwGGpsYkkkekfdlek.kleplklek 105 l pP G+ + + ++ +l+ ++ ++ tr|B3S3E8|B3S3E8_TRIAD 292 LDPPCSGMGQRPCLAYKMSAkELRSYSCYQ 321 999999998888888888655666666654 PP >> tr|B3S9J8|B3S9J8_TRIAD Uncharacterized protein OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_60934 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.8 0.0 1.1e-05 0.011 3 48 .. 73 118 .. 71 160 .. 0.88 Alignments for each domain: == domain 1 score: 14.8 bits; conditional E-value: 1.1e-05 Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvs 48 + +D+ +G+G + q+a +f++vi+ d + ++l +a + + +v tr|B3S9J8|B3S9J8_TRIAD 73 LAIDVGCGSGISTKQYAPYFNRVIGTDHSATQLDQARQENQHPNVT 118 579*******************************998877665555 PP >> tr|B3RUJ8|B3RUJ8_TRIAD Uncharacterized protein OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_24037 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 0.0 3.4e-05 0.032 4 80 .. 137 216 .. 134 219 .. 0.83 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 3.4e-05 Methyltransf_15 4 vlDlfgGaG..GnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfellaklkleei.kvdlvflSpP 80 +lD+++G+G G + +n + iaid++++ + l++ N + + +++ + + dv+++ + +++ vd+++ pP tr|B3RUJ8|B3RUJ8_TRIAD 137 FLDICCGSGaiGLSLLCENPQATCIAIDKDPNAISLTELNSQRLNLGSRMIVEHLDVMKTEFHHGFGHDeAVDFIVSNPP 216 79*****99445555556668899*********************************99766655555546899999999 PP >> tr|B3RI96|B3RI96_TRIAD 40S ribosomal protein S23 OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_63082 PE=3 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 2.9e-05 0.028 78 133 .. 38 97 .. 23 136 .. 0.80 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 2.9e-05 Methyltransf_15 78 SpPwGGpsYkkk...ekfdlekkleplklekllke.svklskniilfLPrnsdlkqlaal 133 P GG s k ek +e k + ++ k++++ +k k+i f Pr+ +l+ +++ tr|B3RI96|B3RI96_TRIAD 38 ANPFGGASHAKGivlEKVGVEAKQPNSAIRKCVRVqLIKNGKKITAFVPRDGCLNYIEEN 97 67999999998722245568889999*******9945678899************99765 PP >> tr|B3S9J7|B3S9J7_TRIAD Uncharacterized protein OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_60933 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.0 6.2e-05 0.06 3 40 .. 51 88 .. 49 100 .. 0.90 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 6.2e-05 Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqh 40 + +D+ +G G + q+a +f+++i+ d + +++ la + tr|B3S9J7|B3S9J7_TRIAD 51 LAIDVGCGPGTSTQQYAPYFNRIIGFDHSATQIDLARQ 88 579****************************9998865 PP >> tr|B3S2J4|B3S2J4_TRIAD Uncharacterized protein OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_58047 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.8 0.0 1.5 1.5e+03 42 73 .. 447 478 .. 426 482 .. 0.86 2 ? 10.8 0.1 0.0002 0.19 4 32 .. 628 656 .. 625 672 .. 0.86 Alignments for each domain: == domain 1 score: -1.8 bits; conditional E-value: 1.5 Methyltransf_15 42 aevYgvsdkvtlvlgdvfellaklkleeikvd 73 a +Y++ +v+ d f+ l +k++ ++ d tr|B3S2J4|B3S2J4_TRIAD 447 AGFYDIMGNVWEWAEDHFNGLPGFKSHYVYHD 478 679**************999999999887666 PP == domain 2 score: 10.8 bits; conditional E-value: 0.0002 Methyltransf_15 4 vlDlfgGaGGnviqfanvfekviaidinl 32 lD+ +G G n+ ++a++f+kv++id tr|B3S2J4|B3S2J4_TRIAD 628 ALDIGCGVGRNSFELAKYFHKVVGIDFGG 656 69***********************9865 PP >> tr|B3S4V8|B3S4V8_TRIAD rRNA adenine N(6)-methyltransferase OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_29342 PE=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 0.0 0.00019 0.19 4 60 .. 27 83 .. 24 133 .. 0.86 2 ? -1.4 0.0 1.1 1e+03 32 66 .. 221 258 .. 205 266 .. 0.62 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.00019 Methyltransf_15 4 vlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfe 60 vl + G+G ++++ + +kvia++++++ + q+ + vs k+++++gdv + tr|B3S4V8|B3S4V8_TRIAD 27 VLEIGPGTGNLTVKLLQKAKKVIACEVDPRLAAELQKRVQGSPVSTKLHIIVGDVLK 83 677778999999******************************************987 PP == domain 2 score: -1.4 bits; conditional E-value: 1.1 Methyltransf_15 32 lsrlklaqhNaev...Ygvsdkvtlvlgdvfellaklk 66 r++++ hN + ++++kv+++l v+ ++ + tr|B3S4V8|B3S4V8_TRIAD 221 NFRIHCSIHNQAIeedINIAEKVDTILKSVNANARRAR 258 34677888887652223567777777776666655555 PP >> tr|B3RZP1|B3RZP1_TRIAD Uncharacterized protein OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_26585 PE=3 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.3 0.0 4.3 4.2e+03 42 61 .. 52 71 .. 44 91 .. 0.63 2 ? 10.9 0.1 0.00018 0.17 3 52 .. 164 216 .. 162 266 .. 0.82 Alignments for each domain: == domain 1 score: -3.3 bits; conditional E-value: 4.3 Methyltransf_15 42 aevYgvsdkvtlvlgdvfel 61 a+ Y+ +d ++ + d+f++ tr|B3RZP1|B3RZP1_TRIAD 52 ANYYNYNDYLMQKFTDLFDI 71 55666666666666666652 PP == domain 2 score: 10.9 bits; conditional E-value: 0.00018 Methyltransf_15 3 vvlDlfgGaGGnviqfanv...fekviaidinlsrlklaqhNaevYgvsdkvt 52 vlD+++ GG++ +a ++a d+n++r+k + N + gv + + tr|B3RZP1|B3RZP1_TRIAD 164 KVLDMCSAPGGKTTYIAALmknTGMIVANDVNKERCKALTANIHRLGVVNTIV 216 79***********9988773333368899**************9999977764 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (165 nodes) Target sequences: 11518 (5222075 residues searched) Passed MSV filter: 458 (0.0397638); expected 230.4 (0.02) Passed bias filter: 293 (0.0254384); expected 230.4 (0.02) Passed Vit filter: 46 (0.00399375); expected 11.5 (0.001) Passed Fwd filter: 12 (0.00104185); expected 0.1 (1e-05) Initial search space (Z): 11518 [actual number of targets] Domain search space (domZ): 12 [number of targets reported over threshold] # CPU time: 0.10u 0.01s 00:00:00.11 Elapsed: 00:00:00.04 # Mc/sec: 21541.06 // [ok]