# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/Methyltransf_15.hmm.txt
# target sequence database:        proteomes/Trypanosoma_brucei.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       Methyltransf_15  [M=165]
Accession:   PF09445.9
Description: RNA cap guanine-N2 methyltransferase
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
    5.8e-05   21.8   0.0    9.9e-05   21.1   0.0    1.3  1  tr|Q4GYR8|Q4GYR8_TRYB2  Uncharacterized protein OS=Trypanosom
    0.00021   20.0   0.6    0.00033   19.4   0.6    1.3  1  tr|Q4FKJ2|Q4FKJ2_TRYB2  Methyltransferase OS=Trypanosoma bruc
     0.0042   15.8   0.0     0.0069   15.1   0.0    1.2  1  tr|Q389Z0|Q389Z0_TRYB2  Uncharacterized protein OS=Trypanosom
  ------ inclusion threshold ------
       0.01   14.5   0.0      0.013   14.2   0.0    1.2  1  tr|Q389B6|Q389B6_TRYB2  Uncharacterized protein OS=Trypanosom
      0.024   13.3   0.0      0.034   12.8   0.0    1.2  1  tr|Q381M3|Q381M3_TRYB2  Uncharacterized protein OS=Trypanosom
      0.058   12.1   0.0      0.099   11.3   0.0    1.3  1  tr|Q38FT0|Q38FT0_TRYB2  Uncharacterized protein OS=Trypanosom


Domain annotation for each sequence (and alignments):
>> tr|Q4GYR8|Q4GYR8_TRYB2  Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=TB
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.1   0.0   6.9e-08   9.9e-05       3      83 ..     399     482 ..     397     486 .. 0.77

  Alignments for each domain:
  == domain 1  score: 21.1 bits;  conditional E-value: 6.9e-08
         Methyltransf_15   3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfellaklkleei...kvdlv.flSpPwGG 83 
                             ++lDl++G+G   i++a+  ++vi+i+  +s ++ a  Nae  gv +  t+ +g v++ll ++ ++     + d+v +l pP  G
  tr|Q4GYR8|Q4GYR8_TRYB2 399 TLLDLCCGTGTIGIALAKHVKRVIGIELVESAVRDARLNAERNGVRN-ATFNCGRVEHLLPSVISQLSpedRKDIVaILDPPRAG 482
                             78*****************************************9975.5788888888655443332222245655245666666 PP

>> tr|Q4FKJ2|Q4FKJ2_TRYB2  Methyltransferase OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb10.6k1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.4   0.6   2.3e-07   0.00033       3      61 ..     107     178 ..     105     205 .. 0.79

  Alignments for each domain:
  == domain 1  score: 19.4 bits;  conditional E-value: 2.3e-07
         Methyltransf_15   3 vvlDlfgGaGGnviqfanv.fekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfe............l 61 
                             +vlD+ +G GG + ++ +   ++v++++ n+++++ a +    Yg+s k+++ + d+ +            +
  tr|Q4FKJ2|Q4FKJ2_TRYB2 107 TVLDVGCGIGGPARNMVRFtSCNVMGVNNNEYQINRARQHDSRYGMSGKINYTKTDFCNmcfgdnefdgayA 178
                             79*********998888764679**********************************985555555555551 PP

>> tr|Q389Z0|Q389Z0_TRYB2  Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.1   0.0   4.9e-06    0.0069       4      61 ..     214     292 ..     212     320 .. 0.76

  Alignments for each domain:
  == domain 1  score: 15.1 bits;  conditional E-value: 4.9e-06
         Methyltransf_15   4 vlDlfgGaGGnviqfanv..fekviaidinlsrlklaqhNaevYgv.sdkvtlvlgdvfe..................l 61 
                             vlD+++G+G   i++a+     +v a+di  + +  +++Na++ g  +++  + + d+fe                  l
  tr|Q389Z0|Q389Z0_TRYB2 214 VLDMCCGTGCVGIAIAKHvpSAQVTAVDILDEAIGASEENAKLNGLeASRFCTLKSDMFEsflvsnsgsltgedtkldL 292
                             8***************9966678**********************96789999999*9997777777777776665541 PP

>> tr|Q389B6|Q389B6_TRYB2  Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.2   0.0   9.1e-06     0.013       3      62 ..     112     171 ..     110     219 .. 0.86

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 9.1e-06
         Methyltransf_15   3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfell 62 
                               lD+ +G+G +++ +a    +v++i+  ++ + + +  a+  +vs +v + + d++e+ 
  tr|Q389B6|Q389B6_TRYB2 112 FALDIGSGSGRDMVFLASRGWHVVGIENRRRLIWQGETLARKHDVSGRVAYLHSDIKEAY 171
                             679****************88***********************************9943 PP

>> tr|Q381M3|Q381M3_TRYB2  Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.0   2.4e-05     0.034       3      49 ..     121     170 ..     119     204 .. 0.79

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 2.4e-05
         Methyltransf_15   3 vvlDlfgGaGGnviqfanv...fekviaidinlsrlklaqhNaevYgvsd 49 
                             +vlDl++G GG++i++ +      +  a +   +r++   +N + Y  s+
  tr|Q381M3|Q381M3_TRYB2 121 LVLDLCAGVGGKSIAISQFlsnSASLTANEQRGDRCARLRRNIKEYVPSN 170
                             69************998883334456666666678999999*99993344 PP

>> tr|Q38FT0|Q38FT0_TRYB2  Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.0   6.9e-05     0.099       3      43 ..     138     178 ..     136     192 .. 0.85

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 6.9e-05
         Methyltransf_15   3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNae 43 
                               lDl +  G  + ++ ++f++v++id++   +k+a +  +
  tr|Q38FT0|Q38FT0_TRYB2 138 RALDLGCAVGASSLEMSKYFSRVVGIDYSVAFIKMARNVVQ 178
                             679******************************99977555 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (165 nodes)
Target sequences:                         8561  (4332363 residues searched)
Passed MSV filter:                       209  (0.024413); expected 171.2 (0.02)
Passed bias filter:                      195  (0.0227777); expected 171.2 (0.02)
Passed Vit filter:                        21  (0.00245298); expected 8.6 (0.001)
Passed Fwd filter:                         6  (0.000700853); expected 0.1 (1e-05)
Initial search space (Z):               8561  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.07u 0.00s 00:00:00.07 Elapsed: 00:00:00.04
# Mc/sec: 17871.00
//
[ok]