# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/Methyltransf_15.hmm.txt # target sequence database: proteomes/Trypanosoma_brucei.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: Methyltransf_15 [M=165] Accession: PF09445.9 Description: RNA cap guanine-N2 methyltransferase Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.8e-05 21.8 0.0 9.9e-05 21.1 0.0 1.3 1 tr|Q4GYR8|Q4GYR8_TRYB2 Uncharacterized protein OS=Trypanosom 0.00021 20.0 0.6 0.00033 19.4 0.6 1.3 1 tr|Q4FKJ2|Q4FKJ2_TRYB2 Methyltransferase OS=Trypanosoma bruc 0.0042 15.8 0.0 0.0069 15.1 0.0 1.2 1 tr|Q389Z0|Q389Z0_TRYB2 Uncharacterized protein OS=Trypanosom ------ inclusion threshold ------ 0.01 14.5 0.0 0.013 14.2 0.0 1.2 1 tr|Q389B6|Q389B6_TRYB2 Uncharacterized protein OS=Trypanosom 0.024 13.3 0.0 0.034 12.8 0.0 1.2 1 tr|Q381M3|Q381M3_TRYB2 Uncharacterized protein OS=Trypanosom 0.058 12.1 0.0 0.099 11.3 0.0 1.3 1 tr|Q38FT0|Q38FT0_TRYB2 Uncharacterized protein OS=Trypanosom Domain annotation for each sequence (and alignments): >> tr|Q4GYR8|Q4GYR8_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=TB # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.1 0.0 6.9e-08 9.9e-05 3 83 .. 399 482 .. 397 486 .. 0.77 Alignments for each domain: == domain 1 score: 21.1 bits; conditional E-value: 6.9e-08 Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfellaklkleei...kvdlv.flSpPwGG 83 ++lDl++G+G i++a+ ++vi+i+ +s ++ a Nae gv + t+ +g v++ll ++ ++ + d+v +l pP G tr|Q4GYR8|Q4GYR8_TRYB2 399 TLLDLCCGTGTIGIALAKHVKRVIGIELVESAVRDARLNAERNGVRN-ATFNCGRVEHLLPSVISQLSpedRKDIVaILDPPRAG 482 78*****************************************9975.5788888888655443332222245655245666666 PP >> tr|Q4FKJ2|Q4FKJ2_TRYB2 Methyltransferase OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb10.6k1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.4 0.6 2.3e-07 0.00033 3 61 .. 107 178 .. 105 205 .. 0.79 Alignments for each domain: == domain 1 score: 19.4 bits; conditional E-value: 2.3e-07 Methyltransf_15 3 vvlDlfgGaGGnviqfanv.fekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfe............l 61 +vlD+ +G GG + ++ + ++v++++ n+++++ a + Yg+s k+++ + d+ + + tr|Q4FKJ2|Q4FKJ2_TRYB2 107 TVLDVGCGIGGPARNMVRFtSCNVMGVNNNEYQINRARQHDSRYGMSGKINYTKTDFCNmcfgdnefdgayA 178 79*********998888764679**********************************985555555555551 PP >> tr|Q389Z0|Q389Z0_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.1 0.0 4.9e-06 0.0069 4 61 .. 214 292 .. 212 320 .. 0.76 Alignments for each domain: == domain 1 score: 15.1 bits; conditional E-value: 4.9e-06 Methyltransf_15 4 vlDlfgGaGGnviqfanv..fekviaidinlsrlklaqhNaevYgv.sdkvtlvlgdvfe..................l 61 vlD+++G+G i++a+ +v a+di + + +++Na++ g +++ + + d+fe l tr|Q389Z0|Q389Z0_TRYB2 214 VLDMCCGTGCVGIAIAKHvpSAQVTAVDILDEAIGASEENAKLNGLeASRFCTLKSDMFEsflvsnsgsltgedtkldL 292 8***************9966678**********************96789999999*9997777777777776665541 PP >> tr|Q389B6|Q389B6_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.2 0.0 9.1e-06 0.013 3 62 .. 112 171 .. 110 219 .. 0.86 Alignments for each domain: == domain 1 score: 14.2 bits; conditional E-value: 9.1e-06 Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfell 62 lD+ +G+G +++ +a +v++i+ ++ + + + a+ +vs +v + + d++e+ tr|Q389B6|Q389B6_TRYB2 112 FALDIGSGSGRDMVFLASRGWHVVGIENRRRLIWQGETLARKHDVSGRVAYLHSDIKEAY 171 679****************88***********************************9943 PP >> tr|Q381M3|Q381M3_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.0 2.4e-05 0.034 3 49 .. 121 170 .. 119 204 .. 0.79 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 2.4e-05 Methyltransf_15 3 vvlDlfgGaGGnviqfanv...fekviaidinlsrlklaqhNaevYgvsd 49 +vlDl++G GG++i++ + + a + +r++ +N + Y s+ tr|Q381M3|Q381M3_TRYB2 121 LVLDLCAGVGGKSIAISQFlsnSASLTANEQRGDRCARLRRNIKEYVPSN 170 69************998883334456666666678999999*99993344 PP >> tr|Q38FT0|Q38FT0_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.0 6.9e-05 0.099 3 43 .. 138 178 .. 136 192 .. 0.85 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 6.9e-05 Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNae 43 lDl + G + ++ ++f++v++id++ +k+a + + tr|Q38FT0|Q38FT0_TRYB2 138 RALDLGCAVGASSLEMSKYFSRVVGIDYSVAFIKMARNVVQ 178 679******************************99977555 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (165 nodes) Target sequences: 8561 (4332363 residues searched) Passed MSV filter: 209 (0.024413); expected 171.2 (0.02) Passed bias filter: 195 (0.0227777); expected 171.2 (0.02) Passed Vit filter: 21 (0.00245298); expected 8.6 (0.001) Passed Fwd filter: 6 (0.000700853); expected 0.1 (1e-05) Initial search space (Z): 8561 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.07u 0.00s 00:00:00.07 Elapsed: 00:00:00.04 # Mc/sec: 17871.00 // [ok]