# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/Methyltransf_15.hmm.txt # target sequence database: proteomes/Xenopus_tropicalis.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: Methyltransf_15 [M=165] Accession: PF09445.9 Description: RNA cap guanine-N2 methyltransferase Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.2e-40 139.4 0.0 2.1e-40 138.6 0.0 1.4 1 tr|F6YTE0|F6YTE0_XENTR Trimethylguanosine synthase 1 OS=Xeno 6.4e-06 26.4 0.3 5.6e-05 23.3 0.0 2.3 2 tr|B1H336|B1H336_XENTR LOC100145545 protein OS=Xenopus tropi 3.6e-05 23.9 0.0 0.00014 22.0 0.0 1.9 2 sp|F6VSS6|TRM5_XENTR tRNA (guanine(37)-N1)-methyltransfera 0.00013 22.1 0.1 0.00034 20.8 0.0 1.7 2 tr|F6ZHI8|F6ZHI8_XENTR Uncharacterized protein OS=Xenopus tr 0.0017 18.5 0.0 0.004 17.3 0.0 1.6 1 tr|F6Y6T0|F6Y6T0_XENTR tRNA methyltransferase 2 homolog B OS 0.0021 18.2 0.1 0.0059 16.8 0.0 1.7 2 tr|F6RCC7|F6RCC7_XENTR NOP2/Sun RNA methyltransferase family 0.0026 17.9 0.0 0.0044 17.2 0.0 1.4 1 tr|F6TRH8|F6TRH8_XENTR Uncharacterized protein OS=Xenopus tr ------ inclusion threshold ------ 0.025 14.7 0.0 0.035 14.2 0.0 1.2 1 tr|F6ZI67|F6ZI67_XENTR EEF1A lysine methyltransferase 2 OS=X 0.027 14.6 0.0 0.041 14.0 0.0 1.2 1 tr|A9UMU1|A9UMU1_XENTR LOC100135405 protein OS=Xenopus tropi 0.13 12.4 0.1 0.8 9.8 0.0 2.0 2 tr|F7E229|F7E229_XENTR Ubiquinone biosynthesis O-methyltrans 0.17 12.0 0.1 0.44 10.7 0.0 1.7 2 tr|A9JTN6|A9JTN6_XENTR LOC100127805 protein (Fragment) OS=Xe 0.19 11.9 0.0 0.55 10.3 0.0 1.7 2 tr|K9J875|K9J875_XENTR rRNA adenine N(6)-methyltransferase O Domain annotation for each sequence (and alignments): >> tr|F6YTE0|F6YTE0_XENTR Trimethylguanosine synthase 1 OS=Xenopus tropicalis OX=8364 GN=tgs1 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 138.6 0.0 1e-43 2.1e-40 2 163 .. 689 840 .. 688 842 .. 0.94 Alignments for each domain: == domain 1 score: 138.6 bits; conditional E-value: 1e-43 Methyltransf_15 2 evvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfellaklkleeikvdlvflSpPwGGpsYkk 88 vv+D+f+G GGn+iqfa+ ++via+di++ +l a +NaevYgv d+++++ gd++ l + lk d vflSpPwGGp+Y tr|F6YTE0|F6YTE0_XENTR 689 GVVVDAFCGVGGNAIQFAKAGNRVIAVDIDPVKLDFARNNAEVYGVTDRIEFIRGDFMLLAQDLK-----ADAVFLSPPWGGPDYVS 770 589******************************************************98877754.....4778************* PP Methyltransf_15 89 kekfdlekkleplklekllkesvklskniilfLPrnsdlkqlaaltaevlenaskvkvvklkenglvkallaylg 163 e+fd+++ l+p ++e +++ s +l+knii fLPrn+d++q+a+l +++ +v++ + n +k++++y+g tr|F6YTE0|F6YTE0_XENTR 771 AETFDIRTILQPNTFE-VFRLSKQLTKNIIYFLPRNTDVEQVASL----AGPGGQVEIEQNFLNKKLKTMTVYFG 840 ******9999998775.799**********************998....8999********************98 PP >> tr|B1H336|B1H336_XENTR LOC100145545 protein OS=Xenopus tropicalis OX=8364 GN=trmt2a PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.2 0.0 0.37 7.5e+02 102 150 .. 46 97 .. 36 118 .. 0.74 2 ! 23.3 0.0 2.8e-08 5.6e-05 2 62 .. 439 498 .. 438 544 .. 0.80 Alignments for each domain: == domain 1 score: 0.2 bits; conditional E-value: 0.37 Methyltransf_15 102 klekllke...svklskniilfLPrnsdlkqlaaltaevlenaskvkvvklk 150 +++ +k ++++ k i LP+ + ++l++++ + n +k+k+++++ tr|B1H336|B1H336_XENTR 46 GIYRYIKDdlfTSEIFKVEIQNLPKYICFNDLKKFLGKYGLNPHKIKLMNKQ 97 56666666333334444446789*********99999999999999976655 PP == domain 2 score: 23.3 bits; conditional E-value: 2.8e-08 Methyltransf_15 2 evvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfell 62 ++vlD+++G+G i +a+ +kv++i+ ++ ++ a+ Na++ d+v++ +g+ ++++ tr|B1H336|B1H336_XENTR 439 TTVLDVCCGTGTIGISLAKKVKKVVGIELCQEAIADAKANAQLN-NLDNVEFRCGKAEDIF 498 579***************************************98.6799****99988843 PP >> sp|F6VSS6|TRM5_XENTR tRNA (guanine(37)-N1)-methyltransferase OS=Xenopus tropicalis OX=8364 GN=trmt5 PE=3 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.6 0.0 1.3 2.6e+03 92 126 .. 151 184 .. 148 241 .. 0.67 2 ! 22.0 0.0 7.1e-08 0.00014 3 69 .. 290 356 .. 288 364 .. 0.90 Alignments for each domain: == domain 1 score: -1.6 bits; conditional E-value: 1.3 Methyltransf_15 92 fdlekkleplklekllkesvklskniilfLPrnsd 126 fd++ ++++++l+ e++k + + LP+ d sp|F6VSS6|TRM5_XENTR 151 FDVNPQVSQYELQLT-YENFKCEEILRAVLPKGQD 184 555555555555332.2333444444444554444 PP == domain 2 score: 22.0 bits; conditional E-value: 7.1e-08 Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfellaklklee 69 v+ D+f+G G ++ a+ ++v+a d n++ k hN+++ v+++v+ d + ++++ ++e sp|F6VSS6|TRM5_XENTR 290 VLFDVFAGVGPFAVPAAKKNCTVYANDLNPESYKWLLHNCKLNKVEKRVQAFNTDGRDFIKTTIKKE 356 789*************************************************999988877665554 PP >> tr|F6ZHI8|F6ZHI8_XENTR Uncharacterized protein OS=Xenopus tropicalis OX=8364 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.8 0.0 1.7e-07 0.00034 3 48 .. 44 93 .. 42 104 .. 0.87 2 ? -2.4 0.0 2.2 4.4e+03 17 51 .. 148 182 .. 146 187 .. 0.71 Alignments for each domain: == domain 1 score: 20.8 bits; conditional E-value: 1.7e-07 Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrl....klaqhNaevYgvs 48 + +D+ +G+G + ++a +f+kvi+id+++s+l k++ hN Y+++ tr|F6ZHI8|F6ZHI8_XENTR 44 LAVDVGCGTGRSTQALAPYFQKVIGIDVSESQLnvarKCTSHNNIYYQIA 93 679****************************9955556888999888876 PP == domain 2 score: -2.4 bits; conditional E-value: 2.2 Methyltransf_15 17 qfanvfekviaidinlsrlklaqhNaevYgvsdkv 51 q+++ e+ a+ + +++ ++q +Y+ ++kv tr|F6ZHI8|F6ZHI8_XENTR 148 QYKEKSEELTAVFNEVRKILMIQASETIYEFNRKV 182 55555566667777778888888888888888877 PP >> tr|F6Y6T0|F6Y6T0_XENTR tRNA methyltransferase 2 homolog B OS=Xenopus tropicalis OX=8364 GN=trmt2b PE=3 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.3 0.0 2e-06 0.004 3 83 .. 275 356 .. 273 369 .. 0.80 Alignments for each domain: == domain 1 score: 17.3 bits; conditional E-value: 2e-06 Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfellaklkleei.k.vdlvflSpPwGG 83 ++lDl++G+G +a +f++vi++++ ++ + a Na + g++ + ++ g ++ll +l + + + l ++ pP G tr|F6Y6T0|F6Y6T0_XENTR 275 TLLDLCCGTGAIGLSLAGYFKNVIGVEMVEDAVLDARWNADFNGIE-NCQFLSGRAEKLLPNLLSYKQkElSVLAVANPPRAG 356 68****************************************9986.678888888887766544443220234455666655 PP >> tr|F6RCC7|F6RCC7_XENTR NOP2/Sun RNA methyltransferase family member 6 OS=Xenopus tropicalis OX=8364 GN=nsun6 PE=3 SV # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.3 0.0 2 4.1e+03 120 148 .. 3 31 .. 1 45 [. 0.79 2 ! 16.8 0.0 2.9e-06 0.0059 3 68 .. 237 301 .. 235 308 .. 0.84 Alignments for each domain: == domain 1 score: -2.3 bits; conditional E-value: 2 Methyltransf_15 120 fLPrnsdlkqlaaltaevlenaskvkvvk 148 f P+ +l++++++v++n++ v+v+ tr|F6RCC7|F6RCC7_XENTR 3 FFPKILLRSELESYLRNVYTNKELVAVIG 31 77888888899999999999999888865 PP == domain 2 score: 16.8 bits; conditional E-value: 2.9e-06 Methyltransf_15 3 vvlDlfgGaGGnviqfanv...fekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfellaklkle 68 +lD+++ GG++ ++a +via+d+ ++++ ++hNa v k++++++ +f+ ++ ++ + tr|F6RCC7|F6RCC7_XENTR 237 RILDMCAAPGGKTTHIATLmkdQGEVIAMDKIANKVEKIKHNASVL----KLKCIKAFCFNSTKAVRDQ 301 79**************998555458********************9....7777777777777776655 PP >> tr|F6TRH8|F6TRH8_XENTR Uncharacterized protein OS=Xenopus tropicalis OX=8364 GN=LOC100485096 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.2 0.0 2.2e-06 0.0044 3 40 .. 44 81 .. 42 109 .. 0.85 Alignments for each domain: == domain 1 score: 17.2 bits; conditional E-value: 2.2e-06 Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqh 40 + +D+ +G+G + ++a f+kvi+idi+ s+l +a + tr|F6TRH8|F6TRH8_XENTR 44 LAVDVGCGTGRSTQALAPHFQKVIGIDISDSQLCVARR 81 679****************************9988765 PP >> tr|F6ZI67|F6ZI67_XENTR EEF1A lysine methyltransferase 2 OS=Xenopus tropicalis OX=8364 GN=EEF1AKMT2 PE=3 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.2 0.0 1.7e-05 0.035 3 96 .. 63 161 .. 61 183 .. 0.74 Alignments for each domain: == domain 1 score: 14.2 bits; conditional E-value: 1.7e-05 Methyltransf_15 3 vvlDlfgGaGGnviqfanv.fekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfe......llaklkleei....kvdlvflS 78 +lD+ +G G +++a++ +++ +id++ + ++la+ +e gvs++ +l + d+ e ++ + ++d v l tr|F6ZI67|F6ZI67_XENTR 63 SILDIGTGNGMLLVELAKSgYCNLTGIDYSSDAVELAKSICEKEGVSQNAQLQVTDFLEdfhpsqQ-----FDVCldkgTFDAVSLD 144 589***************999************************************994444431.....2222222234555442 PP Methyltransf_15 79 pPwGGpsYkkkekfdlek 96 P+G + +++ + +l++ tr|F6ZI67|F6ZI67_XENTR 145 -PTGATEKREQYVRSLCQ 161 .55555555555555555 PP >> tr|A9UMU1|A9UMU1_XENTR LOC100135405 protein OS=Xenopus tropicalis OX=8364 GN=LOC100135405 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.0 0.0 2.1e-05 0.041 14 77 .. 72 140 .. 61 142 .. 0.84 Alignments for each domain: == domain 1 score: 14.0 bits; conditional E-value: 2.1e-05 Methyltransf_15 14 nviqfanv...fekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfellaklkleei..kvdlvfl 77 +i +a+ + +++in+++ +a++ ++ gv+dkv++ lg ++++ +l++++ ++d+vf+ tr|A9UMU1|A9UMU1_XENTR 72 SAIRIARLlkpGARLLTVEINPDNASVAKQMIQFAGVEDKVQILLGSTETVIPNLRTQHGvkHFDFVFI 140 55666655455778999************************************9999876668999996 PP >> tr|F7E229|F7E229_XENTR Ubiquinone biosynthesis O-methyltransferase, mitochondrial OS=Xenopus tropicalis OX=8364 GN=c # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.0 0.0 0.4 8.1e+02 27 55 .. 22 49 .. 15 75 .. 0.76 2 ? 9.8 0.0 0.0004 0.8 4 64 .. 103 164 .. 101 209 .. 0.88 Alignments for each domain: == domain 1 score: 0.0 bits; conditional E-value: 0.4 Methyltransf_15 27 aidinlsrlklaqhNaevYgvsdkvtlvl 55 +++ n++r ++ hN ++Y s+ v+ tr|F7E229|F7E229_XENTR 22 SCNENENRGNI-CHNFRMYATSQTVDPLE 49 66666666655.49*****9999998765 PP == domain 2 score: 9.8 bits; conditional E-value: 0.0004 Methyltransf_15 4 vlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgv.sdkvtlvlgdvfellak 64 +lD+ +G+G + + + +v +id ++++k+a + + v +++v+++ + v+el+ tr|F7E229|F7E229_XENTR 103 ILDVGCGGGLLSEPLGRLGASVTGIDPLEDNIKIAAQHKSFDPVlDKQVQYKSCTVEELVDG 164 89********************************99999998886788*********98865 PP >> tr|A9JTN6|A9JTN6_XENTR LOC100127805 protein (Fragment) OS=Xenopus tropicalis OX=8364 GN=LOC100127805 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.7 0.0 0.00022 0.44 4 41 .. 52 89 .. 49 103 .. 0.89 2 ? -1.5 0.0 1.2 2.4e+03 64 64 .. 187 187 .. 130 240 .. 0.61 Alignments for each domain: == domain 1 score: 10.7 bits; conditional E-value: 0.00022 Methyltransf_15 4 vlDlfgGaGGnviqfanvfekviaidinlsrlklaqhN 41 +D+ +G+G + + +f+kv + di++ ++++a+h tr|A9JTN6|A9JTN6_XENTR 52 AVDVGCGTGQTSRSLVPYFQKVLGTDISEAQIEQANHA 89 69*********************************995 PP == domain 2 score: -1.5 bits; conditional E-value: 1.2 Methyltransf_15 64 k 64 + tr|A9JTN6|A9JTN6_XENTR 187 T 187 2 PP >> tr|K9J875|K9J875_XENTR rRNA adenine N(6)-methyltransferase OS=Xenopus tropicalis OX=8364 GN=dimt1 PE=3 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.3 0.0 0.00027 0.55 3 60 .. 59 116 .. 57 166 .. 0.86 2 ? -1.6 0.0 1.3 2.6e+03 30 44 .. 252 266 .. 235 296 .. 0.62 Alignments for each domain: == domain 1 score: 10.3 bits; conditional E-value: 0.00027 Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfe 60 vvl + G+G ++++ + ++v+a++ +++ ++ q+ + v++k+++++gdv + tr|K9J875|K9J875_XENTR 59 VVLEVGPGTGNMTMKLLEKAKRVVACELDTRLVAELQKRVQGSAVASKLQVMVGDVLK 116 6788888999999999999************************************987 PP == domain 2 score: -1.6 bits; conditional E-value: 1.3 Methyltransf_15 30 inlsrlklaqhNaev 44 + ++++++ hN v tr|K9J875|K9J875_XENTR 252 EKNYKIHCSLHNISV 266 355678888888765 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (165 nodes) Target sequences: 24182 (11782085 residues searched) Passed MSV filter: 736 (0.0304359); expected 483.6 (0.02) Passed bias filter: 562 (0.0232404); expected 483.6 (0.02) Passed Vit filter: 49 (0.0020263); expected 24.2 (0.001) Passed Fwd filter: 12 (0.000496237); expected 0.2 (1e-05) Initial search space (Z): 24182 [actual number of targets] Domain search space (domZ): 12 [number of targets reported over threshold] # CPU time: 0.17u 0.01s 00:00:00.18 Elapsed: 00:00:00.08 # Mc/sec: 24300.55 // [ok]