# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/Methyltransf_15.hmm.txt
# target sequence database: proteomes/Xenopus_tropicalis.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: Methyltransf_15 [M=165]
Accession: PF09445.9
Description: RNA cap guanine-N2 methyltransferase
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
1.2e-40 139.4 0.0 2.1e-40 138.6 0.0 1.4 1 tr|F6YTE0|F6YTE0_XENTR Trimethylguanosine synthase 1 OS=Xeno
6.4e-06 26.4 0.3 5.6e-05 23.3 0.0 2.3 2 tr|B1H336|B1H336_XENTR LOC100145545 protein OS=Xenopus tropi
3.6e-05 23.9 0.0 0.00014 22.0 0.0 1.9 2 sp|F6VSS6|TRM5_XENTR tRNA (guanine(37)-N1)-methyltransfera
0.00013 22.1 0.1 0.00034 20.8 0.0 1.7 2 tr|F6ZHI8|F6ZHI8_XENTR Uncharacterized protein OS=Xenopus tr
0.0017 18.5 0.0 0.004 17.3 0.0 1.6 1 tr|F6Y6T0|F6Y6T0_XENTR tRNA methyltransferase 2 homolog B OS
0.0021 18.2 0.1 0.0059 16.8 0.0 1.7 2 tr|F6RCC7|F6RCC7_XENTR NOP2/Sun RNA methyltransferase family
0.0026 17.9 0.0 0.0044 17.2 0.0 1.4 1 tr|F6TRH8|F6TRH8_XENTR Uncharacterized protein OS=Xenopus tr
------ inclusion threshold ------
0.025 14.7 0.0 0.035 14.2 0.0 1.2 1 tr|F6ZI67|F6ZI67_XENTR EEF1A lysine methyltransferase 2 OS=X
0.027 14.6 0.0 0.041 14.0 0.0 1.2 1 tr|A9UMU1|A9UMU1_XENTR LOC100135405 protein OS=Xenopus tropi
0.13 12.4 0.1 0.8 9.8 0.0 2.0 2 tr|F7E229|F7E229_XENTR Ubiquinone biosynthesis O-methyltrans
0.17 12.0 0.1 0.44 10.7 0.0 1.7 2 tr|A9JTN6|A9JTN6_XENTR LOC100127805 protein (Fragment) OS=Xe
0.19 11.9 0.0 0.55 10.3 0.0 1.7 2 tr|K9J875|K9J875_XENTR rRNA adenine N(6)-methyltransferase O
Domain annotation for each sequence (and alignments):
>> tr|F6YTE0|F6YTE0_XENTR Trimethylguanosine synthase 1 OS=Xenopus tropicalis OX=8364 GN=tgs1 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 138.6 0.0 1e-43 2.1e-40 2 163 .. 689 840 .. 688 842 .. 0.94
Alignments for each domain:
== domain 1 score: 138.6 bits; conditional E-value: 1e-43
Methyltransf_15 2 evvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfellaklkleeikvdlvflSpPwGGpsYkk 88
vv+D+f+G GGn+iqfa+ ++via+di++ +l a +NaevYgv d+++++ gd++ l + lk d vflSpPwGGp+Y
tr|F6YTE0|F6YTE0_XENTR 689 GVVVDAFCGVGGNAIQFAKAGNRVIAVDIDPVKLDFARNNAEVYGVTDRIEFIRGDFMLLAQDLK-----ADAVFLSPPWGGPDYVS 770
589******************************************************98877754.....4778************* PP
Methyltransf_15 89 kekfdlekkleplklekllkesvklskniilfLPrnsdlkqlaaltaevlenaskvkvvklkenglvkallaylg 163
e+fd+++ l+p ++e +++ s +l+knii fLPrn+d++q+a+l +++ +v++ + n +k++++y+g
tr|F6YTE0|F6YTE0_XENTR 771 AETFDIRTILQPNTFE-VFRLSKQLTKNIIYFLPRNTDVEQVASL----AGPGGQVEIEQNFLNKKLKTMTVYFG 840
******9999998775.799**********************998....8999********************98 PP
>> tr|B1H336|B1H336_XENTR LOC100145545 protein OS=Xenopus tropicalis OX=8364 GN=trmt2a PE=2 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 0.2 0.0 0.37 7.5e+02 102 150 .. 46 97 .. 36 118 .. 0.74
2 ! 23.3 0.0 2.8e-08 5.6e-05 2 62 .. 439 498 .. 438 544 .. 0.80
Alignments for each domain:
== domain 1 score: 0.2 bits; conditional E-value: 0.37
Methyltransf_15 102 klekllke...svklskniilfLPrnsdlkqlaaltaevlenaskvkvvklk 150
+++ +k ++++ k i LP+ + ++l++++ + n +k+k+++++
tr|B1H336|B1H336_XENTR 46 GIYRYIKDdlfTSEIFKVEIQNLPKYICFNDLKKFLGKYGLNPHKIKLMNKQ 97
56666666333334444446789*********99999999999999976655 PP
== domain 2 score: 23.3 bits; conditional E-value: 2.8e-08
Methyltransf_15 2 evvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfell 62
++vlD+++G+G i +a+ +kv++i+ ++ ++ a+ Na++ d+v++ +g+ ++++
tr|B1H336|B1H336_XENTR 439 TTVLDVCCGTGTIGISLAKKVKKVVGIELCQEAIADAKANAQLN-NLDNVEFRCGKAEDIF 498
579***************************************98.6799****99988843 PP
>> sp|F6VSS6|TRM5_XENTR tRNA (guanine(37)-N1)-methyltransferase OS=Xenopus tropicalis OX=8364 GN=trmt5 PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? -1.6 0.0 1.3 2.6e+03 92 126 .. 151 184 .. 148 241 .. 0.67
2 ! 22.0 0.0 7.1e-08 0.00014 3 69 .. 290 356 .. 288 364 .. 0.90
Alignments for each domain:
== domain 1 score: -1.6 bits; conditional E-value: 1.3
Methyltransf_15 92 fdlekkleplklekllkesvklskniilfLPrnsd 126
fd++ ++++++l+ e++k + + LP+ d
sp|F6VSS6|TRM5_XENTR 151 FDVNPQVSQYELQLT-YENFKCEEILRAVLPKGQD 184
555555555555332.2333444444444554444 PP
== domain 2 score: 22.0 bits; conditional E-value: 7.1e-08
Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfellaklklee 69
v+ D+f+G G ++ a+ ++v+a d n++ k hN+++ v+++v+ d + ++++ ++e
sp|F6VSS6|TRM5_XENTR 290 VLFDVFAGVGPFAVPAAKKNCTVYANDLNPESYKWLLHNCKLNKVEKRVQAFNTDGRDFIKTTIKKE 356
789*************************************************999988877665554 PP
>> tr|F6ZHI8|F6ZHI8_XENTR Uncharacterized protein OS=Xenopus tropicalis OX=8364 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 20.8 0.0 1.7e-07 0.00034 3 48 .. 44 93 .. 42 104 .. 0.87
2 ? -2.4 0.0 2.2 4.4e+03 17 51 .. 148 182 .. 146 187 .. 0.71
Alignments for each domain:
== domain 1 score: 20.8 bits; conditional E-value: 1.7e-07
Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrl....klaqhNaevYgvs 48
+ +D+ +G+G + ++a +f+kvi+id+++s+l k++ hN Y+++
tr|F6ZHI8|F6ZHI8_XENTR 44 LAVDVGCGTGRSTQALAPYFQKVIGIDVSESQLnvarKCTSHNNIYYQIA 93
679****************************9955556888999888876 PP
== domain 2 score: -2.4 bits; conditional E-value: 2.2
Methyltransf_15 17 qfanvfekviaidinlsrlklaqhNaevYgvsdkv 51
q+++ e+ a+ + +++ ++q +Y+ ++kv
tr|F6ZHI8|F6ZHI8_XENTR 148 QYKEKSEELTAVFNEVRKILMIQASETIYEFNRKV 182
55555566667777778888888888888888877 PP
>> tr|F6Y6T0|F6Y6T0_XENTR tRNA methyltransferase 2 homolog B OS=Xenopus tropicalis OX=8364 GN=trmt2b PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 17.3 0.0 2e-06 0.004 3 83 .. 275 356 .. 273 369 .. 0.80
Alignments for each domain:
== domain 1 score: 17.3 bits; conditional E-value: 2e-06
Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfellaklkleei.k.vdlvflSpPwGG 83
++lDl++G+G +a +f++vi++++ ++ + a Na + g++ + ++ g ++ll +l + + + l ++ pP G
tr|F6Y6T0|F6Y6T0_XENTR 275 TLLDLCCGTGAIGLSLAGYFKNVIGVEMVEDAVLDARWNADFNGIE-NCQFLSGRAEKLLPNLLSYKQkElSVLAVANPPRAG 356
68****************************************9986.678888888887766544443220234455666655 PP
>> tr|F6RCC7|F6RCC7_XENTR NOP2/Sun RNA methyltransferase family member 6 OS=Xenopus tropicalis OX=8364 GN=nsun6 PE=3 SV
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? -2.3 0.0 2 4.1e+03 120 148 .. 3 31 .. 1 45 [. 0.79
2 ! 16.8 0.0 2.9e-06 0.0059 3 68 .. 237 301 .. 235 308 .. 0.84
Alignments for each domain:
== domain 1 score: -2.3 bits; conditional E-value: 2
Methyltransf_15 120 fLPrnsdlkqlaaltaevlenaskvkvvk 148
f P+ +l++++++v++n++ v+v+
tr|F6RCC7|F6RCC7_XENTR 3 FFPKILLRSELESYLRNVYTNKELVAVIG 31
77888888899999999999999888865 PP
== domain 2 score: 16.8 bits; conditional E-value: 2.9e-06
Methyltransf_15 3 vvlDlfgGaGGnviqfanv...fekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfellaklkle 68
+lD+++ GG++ ++a +via+d+ ++++ ++hNa v k++++++ +f+ ++ ++ +
tr|F6RCC7|F6RCC7_XENTR 237 RILDMCAAPGGKTTHIATLmkdQGEVIAMDKIANKVEKIKHNASVL----KLKCIKAFCFNSTKAVRDQ 301
79**************998555458********************9....7777777777777776655 PP
>> tr|F6TRH8|F6TRH8_XENTR Uncharacterized protein OS=Xenopus tropicalis OX=8364 GN=LOC100485096 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 17.2 0.0 2.2e-06 0.0044 3 40 .. 44 81 .. 42 109 .. 0.85
Alignments for each domain:
== domain 1 score: 17.2 bits; conditional E-value: 2.2e-06
Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqh 40
+ +D+ +G+G + ++a f+kvi+idi+ s+l +a +
tr|F6TRH8|F6TRH8_XENTR 44 LAVDVGCGTGRSTQALAPHFQKVIGIDISDSQLCVARR 81
679****************************9988765 PP
>> tr|F6ZI67|F6ZI67_XENTR EEF1A lysine methyltransferase 2 OS=Xenopus tropicalis OX=8364 GN=EEF1AKMT2 PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 14.2 0.0 1.7e-05 0.035 3 96 .. 63 161 .. 61 183 .. 0.74
Alignments for each domain:
== domain 1 score: 14.2 bits; conditional E-value: 1.7e-05
Methyltransf_15 3 vvlDlfgGaGGnviqfanv.fekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfe......llaklkleei....kvdlvflS 78
+lD+ +G G +++a++ +++ +id++ + ++la+ +e gvs++ +l + d+ e ++ + ++d v l
tr|F6ZI67|F6ZI67_XENTR 63 SILDIGTGNGMLLVELAKSgYCNLTGIDYSSDAVELAKSICEKEGVSQNAQLQVTDFLEdfhpsqQ-----FDVCldkgTFDAVSLD 144
589***************999************************************994444431.....2222222234555442 PP
Methyltransf_15 79 pPwGGpsYkkkekfdlek 96
P+G + +++ + +l++
tr|F6ZI67|F6ZI67_XENTR 145 -PTGATEKREQYVRSLCQ 161
.55555555555555555 PP
>> tr|A9UMU1|A9UMU1_XENTR LOC100135405 protein OS=Xenopus tropicalis OX=8364 GN=LOC100135405 PE=2 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 14.0 0.0 2.1e-05 0.041 14 77 .. 72 140 .. 61 142 .. 0.84
Alignments for each domain:
== domain 1 score: 14.0 bits; conditional E-value: 2.1e-05
Methyltransf_15 14 nviqfanv...fekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfellaklkleei..kvdlvfl 77
+i +a+ + +++in+++ +a++ ++ gv+dkv++ lg ++++ +l++++ ++d+vf+
tr|A9UMU1|A9UMU1_XENTR 72 SAIRIARLlkpGARLLTVEINPDNASVAKQMIQFAGVEDKVQILLGSTETVIPNLRTQHGvkHFDFVFI 140
55666655455778999************************************9999876668999996 PP
>> tr|F7E229|F7E229_XENTR Ubiquinone biosynthesis O-methyltransferase, mitochondrial OS=Xenopus tropicalis OX=8364 GN=c
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 0.0 0.0 0.4 8.1e+02 27 55 .. 22 49 .. 15 75 .. 0.76
2 ? 9.8 0.0 0.0004 0.8 4 64 .. 103 164 .. 101 209 .. 0.88
Alignments for each domain:
== domain 1 score: 0.0 bits; conditional E-value: 0.4
Methyltransf_15 27 aidinlsrlklaqhNaevYgvsdkvtlvl 55
+++ n++r ++ hN ++Y s+ v+
tr|F7E229|F7E229_XENTR 22 SCNENENRGNI-CHNFRMYATSQTVDPLE 49
66666666655.49*****9999998765 PP
== domain 2 score: 9.8 bits; conditional E-value: 0.0004
Methyltransf_15 4 vlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgv.sdkvtlvlgdvfellak 64
+lD+ +G+G + + + +v +id ++++k+a + + v +++v+++ + v+el+
tr|F7E229|F7E229_XENTR 103 ILDVGCGGGLLSEPLGRLGASVTGIDPLEDNIKIAAQHKSFDPVlDKQVQYKSCTVEELVDG 164
89********************************99999998886788*********98865 PP
>> tr|A9JTN6|A9JTN6_XENTR LOC100127805 protein (Fragment) OS=Xenopus tropicalis OX=8364 GN=LOC100127805 PE=2 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 10.7 0.0 0.00022 0.44 4 41 .. 52 89 .. 49 103 .. 0.89
2 ? -1.5 0.0 1.2 2.4e+03 64 64 .. 187 187 .. 130 240 .. 0.61
Alignments for each domain:
== domain 1 score: 10.7 bits; conditional E-value: 0.00022
Methyltransf_15 4 vlDlfgGaGGnviqfanvfekviaidinlsrlklaqhN 41
+D+ +G+G + + +f+kv + di++ ++++a+h
tr|A9JTN6|A9JTN6_XENTR 52 AVDVGCGTGQTSRSLVPYFQKVLGTDISEAQIEQANHA 89
69*********************************995 PP
== domain 2 score: -1.5 bits; conditional E-value: 1.2
Methyltransf_15 64 k 64
+
tr|A9JTN6|A9JTN6_XENTR 187 T 187
2 PP
>> tr|K9J875|K9J875_XENTR rRNA adenine N(6)-methyltransferase OS=Xenopus tropicalis OX=8364 GN=dimt1 PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 10.3 0.0 0.00027 0.55 3 60 .. 59 116 .. 57 166 .. 0.86
2 ? -1.6 0.0 1.3 2.6e+03 30 44 .. 252 266 .. 235 296 .. 0.62
Alignments for each domain:
== domain 1 score: 10.3 bits; conditional E-value: 0.00027
Methyltransf_15 3 vvlDlfgGaGGnviqfanvfekviaidinlsrlklaqhNaevYgvsdkvtlvlgdvfe 60
vvl + G+G ++++ + ++v+a++ +++ ++ q+ + v++k+++++gdv +
tr|K9J875|K9J875_XENTR 59 VVLEVGPGTGNMTMKLLEKAKRVVACELDTRLVAELQKRVQGSAVASKLQVMVGDVLK 116
6788888999999999999************************************987 PP
== domain 2 score: -1.6 bits; conditional E-value: 1.3
Methyltransf_15 30 inlsrlklaqhNaev 44
+ ++++++ hN v
tr|K9J875|K9J875_XENTR 252 EKNYKIHCSLHNISV 266
355678888888765 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (165 nodes)
Target sequences: 24182 (11782085 residues searched)
Passed MSV filter: 736 (0.0304359); expected 483.6 (0.02)
Passed bias filter: 562 (0.0232404); expected 483.6 (0.02)
Passed Vit filter: 49 (0.0020263); expected 24.2 (0.001)
Passed Fwd filter: 12 (0.000496237); expected 0.2 (1e-05)
Initial search space (Z): 24182 [actual number of targets]
Domain search space (domZ): 12 [number of targets reported over threshold]
# CPU time: 0.17u 0.01s 00:00:00.18 Elapsed: 00:00:00.08
# Mc/sec: 24300.55
//
[ok]