# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/Methyltransf_4.hmm.txt
# target sequence database: proteomes/Anolis_carolinensis.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: Methyltransf_4 [M=173]
Accession: PF02390.16
Description: Putative methyltransferase
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
5.8e-59 198.5 0.0 7.4e-59 198.1 0.0 1.1 1 tr|G1KN86|G1KN86_ANOCA tRNA (guanine-N(7)-)-methyltransferas
4.4e-07 29.6 0.1 1.2e-06 28.2 0.1 1.8 2 tr|H9GDC5|H9GDC5_ANOCA tRNA methyltransferase 2 homolog A OS
0.00011 21.8 0.0 0.00018 21.1 0.0 1.3 1 tr|R4GAD1|R4GAD1_ANOCA HemK methyltransferase family member
0.00036 20.1 0.0 0.00065 19.3 0.0 1.4 1 tr|G1KT61|G1KT61_ANOCA Uncharacterized protein OS=Anolis car
0.002 17.7 0.0 0.0036 16.8 0.0 1.4 1 tr|G1KPU8|G1KPU8_ANOCA EEF1A lysine methyltransferase 2 OS=A
0.0042 16.6 0.0 0.0082 15.7 0.0 1.4 1 tr|H9GDY8|H9GDY8_ANOCA Glutathione S-transferase C-terminal
0.0083 15.7 0.0 0.018 14.6 0.0 1.7 1 tr|G1K8K6|G1K8K6_ANOCA THUMP domain containing 2 OS=Anolis c
------ inclusion threshold ------
0.01 15.4 0.1 0.32 10.5 0.0 2.7 2 tr|G1KB01|G1KB01_ANOCA Exportin 4 OS=Anolis carolinensis OX=
0.014 14.9 0.1 0.046 13.2 0.1 1.9 2 tr|H9GG55|H9GG55_ANOCA Protein arginine N-methyltransferase
0.02 14.4 0.0 0.13 11.8 0.0 2.0 2 tr|H9GHU6|H9GHU6_ANOCA Methylphosphate capping enzyme OS=Ano
0.025 14.1 0.0 0.039 13.5 0.0 1.3 1 tr|H9GNU1|H9GNU1_ANOCA Methyltransferase like 5 OS=Anolis ca
0.17 11.4 0.1 0.3 10.6 0.1 1.4 1 tr|H9G9N1|H9G9N1_ANOCA Protein arginine methyltransferase 1
Domain annotation for each sequence (and alignments):
>> tr|G1KN86|G1KN86_ANOCA tRNA (guanine-N(7)-)-methyltransferase OS=Anolis carolinensis OX=28377 GN=METTL1 PE=3 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 198.1 0.0 4.8e-62 7.4e-59 2 172 .. 69 245 .. 68 246 .. 0.98
Alignments for each domain:
== domain 1 score: 198.1 bits; conditional E-value: 4.8e-62
-EEEEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHC......TTSSEEEEES-CCCHHHHCS-TTSEEEEEEES-- CS
Methyltransf_4 2 apvvleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkieal......elkNlrilrgdalkvllelledgslekifilFPD 82
++ +++iGcG+G++lval++ +P++++lG+Eirvkv+++v ++i+ l +++N++++r++a+k+l++++++g+l+k+f+lFPD
tr|G1KN86|G1KN86_ANOCA 69 QVEFADIGCGYGGLLVALSPLFPNTLMLGLEIRVKVSDYVQDRIRSLrashagQFQNVACIRSNAMKHLPNFFHKGQLCKMFFLFPD 155
7889*********************************************************************************** PP
---SGGGGGGSTTSHHHHHHHHHHEEEEEEEEEEESHHHHHHHHHHHHHCSTTEEESSCCCSCCTCHCHHCCCSSTTCCCCCCTTSS CS
Methyltransf_4 83 PwfKkrhhKrRllqpellkelarvLkkgGvlelaTDveeyaeemlkvleeeplferlskeeeleeeplsvlriatkyeqkvqskgke 169
P+fKk +hK+R+++++ll+e+a+vL+++G+++++TDvee++++m++++ee+plfe++ +e ++++++ l +t++++kvq++g++
tr|G1KN86|G1KN86_ANOCA 156 PHFKKTKHKWRIISSTLLAEYAYVLREEGLVYTITDVEEVHKWMVTHFEEHPLFEQVPLKELSSDPIIDLLGTSTEEGKKVQRNGGK 242
**************************************************************************************9 PP
-EE CS
Methyltransf_4 170 iye 172
+
tr|G1KN86|G1KN86_ANOCA 243 TFP 245
886 PP
>> tr|H9GDC5|H9GDC5_ANOCA tRNA methyltransferase 2 homolog A OS=Anolis carolinensis OX=28377 GN=TRMT2A PE=3 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? -3.8 0.0 5.2 8e+03 106 145 .. 348 387 .. 346 392 .. 0.69
2 ! 28.2 0.1 7.7e-10 1.2e-06 3 75 .. 446 516 .. 444 524 .. 0.91
Alignments for each domain:
== domain 1 score: -3.8 bits; conditional E-value: 5.2
HEEEEEEEEEEESHHHHHHHHHHHHHCSTTEEESSCCCSC CS
Methyltransf_4 106 vLkkgGvlelaTDveeyaeemlkvleeeplferlskeeel 145
+ k+G+ el+T v +y+ e + + + +++ ++++ +++
tr|H9GDC5|H9GDC5_ANOCA 348 KVSKEGLTELQTSVAKYFMEGAGKESGITSLYFVEEGQKK 387
5678899999999999988877666666666666655555 PP
== domain 2 score: 28.2 bits; conditional E-value: 7.7e-10
EEEEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTTSSEEEEES-CCCHHHHCS-TTSEEE CS
Methyltransf_4 3 pvvleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkiealelkNlrilrgdalkvllelledgslek 75
+vl+++cG G++ ++lAkk k+++GiE+ ++ v+ + +++ ++l+N++ +g a +++++l++ l++
tr|H9GDC5|H9GDC5_ANOCA 446 TTVLDVCCGTGTIGITLAKKV--KKVIGIELCQEAVEDAKVNAQLNDLNNVEFYCGKAEDLVPQLVNSLALQN 516
679****************96..889********************************999999988777765 PP
>> tr|R4GAD1|R4GAD1_ANOCA HemK methyltransferase family member 1 OS=Anolis carolinensis OX=28377 GN=HEMK1 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 21.1 0.0 1.1e-07 0.00018 2 51 .. 180 229 .. 179 250 .. 0.88
Alignments for each domain:
== domain 1 score: 21.1 bits; conditional E-value: 1.1e-07
-EEEEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTTS CS
Methyltransf_4 2 apvvleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkiealelk 51
pv+le+GcG+G + + l kk P+ ++++i++ + v+ +++e+l+l+
tr|R4GAD1|R4GAD1_ANOCA 180 GPVILEVGCGSGAIALSLLKKLPHSKVIAIDKLEAAVNLTKENAERLNLQ 229
589**********************************9999999999876 PP
>> tr|G1KT61|G1KT61_ANOCA Uncharacterized protein OS=Anolis carolinensis OX=28377 PE=4 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 19.3 0.0 4.2e-07 0.00065 6 54 .. 31 79 .. 27 85 .. 0.96
Alignments for each domain:
== domain 1 score: 19.3 bits; conditional E-value: 4.2e-07
EEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTTSSEE CS
Methyltransf_4 6 leiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkiealelkNlr 54
le+G+G G+++v+ A++ P++++ Ei+ + + + + i+a +++N+r
tr|G1KT61|G1KT61_ANOCA 31 LELGSGTGQHVVHFAQALPTVTWQPSEISPASQQSISAYIRATKVTNVR 79
8**********************************************97 PP
>> tr|G1KPU8|G1KPU8_ANOCA EEF1A lysine methyltransferase 2 OS=Anolis carolinensis OX=28377 GN=eef1akmt2 PE=3 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 16.8 0.0 2.3e-06 0.0036 4 116 .. 62 170 .. 60 189 .. 0.84
Alignments for each domain:
== domain 1 score: 16.8 bits; conditional E-value: 2.3e-06
EEEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTTSSEEEEES-C......CCHHHHCS-TTSEEEEEEES---- CS
Methyltransf_4 4 vvleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkiealelkNlrilrgda......lkvllelledgslekifilFPDPw 84
vl+iG+G+G +lv+lAk +n+ Gi+ + v+ + +e+++l +++ d l ++ + +g+++ i+++ PD
tr|G1KPU8|G1KPU8_ANOCA 62 SVLDIGTGNGVLLVELAKS-GYTNLTGIDYCPSAVQLSKSIMEKEGLPHVKLQVEDIlnpsdeLSGFQVCIDKGTFDAISLN-PDNA 146
589**************86.578999*****999999999999998888888887776666668899999*********998.8887 PP
-SGGGGGGSTTSHHHHHHHHHHEEEEEEEEEE CS
Methyltransf_4 85 fKkrhhKrRllqpellkelarvLkkgGvlela 116
+kr+ + +k l++vL++gG++ +
tr|G1KPU8|G1KPU8_ANOCA 147 AEKRK--------QYVKSLHKVLRPGGFFLIT 170
77777........7889999999999987654 PP
>> tr|H9GDY8|H9GDY8_ANOCA Glutathione S-transferase C-terminal domain containing OS=Anolis carolinensis OX=28377 GN=GST
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 15.7 0.0 5.3e-06 0.0082 4 68 .. 528 591 .. 525 595 .. 0.94
Alignments for each domain:
== domain 1 score: 15.7 bits; conditional E-value: 5.3e-06
EEEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTTSSEEEEES-CCCHHHHCS CS
Methyltransf_4 4 vvleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkiealelkNlrilrgdalkvllell 68
+v++ ++G G++ + A+ P+++++ +E ++ ++ ++ ++ ++l+l+N+ l+ + +++++ ++
tr|H9GDY8|H9GDY8_ANOCA 528 IVVDFCSGGGHVGIVVAHILPSCQVVLVENKELSLVRAKERSDELGLNNVWFLQAN-MDYFKGVF 591
79******************************************************.69998776 PP
>> tr|G1K8K6|G1K8K6_ANOCA THUMP domain containing 2 OS=Anolis carolinensis OX=28377 GN=THUMPD2 PE=4 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 14.6 0.0 1.2e-05 0.018 5 50 .. 273 318 .. 269 381 .. 0.86
Alignments for each domain:
== domain 1 score: 14.6 bits; conditional E-value: 1.2e-05
EEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTT CS
Methyltransf_4 5 vleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkiealel 50
vl+ cG G++l++ A + Pd+n+lG +i+ ++ + +i+a +l
tr|G1K8K6|G1K8K6_ANOCA 273 VLDPTCGLGTILLEAAMEWPDVNYLGTDISDAQLQGAYTNIKAANL 318
67788****************************9999999998754 PP
>> tr|G1KB01|G1KB01_ANOCA Exportin 4 OS=Anolis carolinensis OX=28377 GN=XPO4 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 10.5 0.0 0.00021 0.32 58 152 .. 703 810 .. 680 827 .. 0.79
2 ? 1.5 0.1 0.12 1.8e+02 17 57 .. 844 884 .. 838 899 .. 0.86
Alignments for each domain:
== domain 1 score: 10.5 bits; conditional E-value: 0.00021
S-CCCHHHHCS-TTSEEEEEEES-----SGGGGGGS.....TTSHHHHHHHHHHEEEEEEEEEEES.........HHHHHHHHHHHH CS
Methyltransf_4 58 gdalkvllelledgslekifilFPDPwfKkrhhKrR.....llqpellkelarvLkkgGvlelaTD.........veeyaeemlkvl 130
+d +++l +l+e ++ ++i+i+ w+ +++ rR +l++ + l+++L+ gG+ ++ +D + +++++ l+v+
tr|G1KB01|G1KB01_ANOCA 703 NDTVQLLVTLVERRERANIVIHCENWWNLAKQFARRspplhILSSSVQRTLMKALVLGGFAHMESDakqqywtevLHPLQQRFLNVI 789
45588888888888888898888888888888888877777889999999****************987776666666677777777 PP
HCSTTEEESSCCCSCCTCHCHH CS
Methyltransf_4 131 eeeplferlskeeeleeeplsv 152
++e +f+++++eee+++e++ +
tr|G1KB01|G1KB01_ANOCA 790 NQE-NFQQICQEEEVKQEITAT 810
777.888888888888777655 PP
== domain 2 score: 1.5 bits; conditional E-value: 0.12
HHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTTSSEEEEE CS
Methyltransf_4 17 valAkknPdknflGiEirvkvvakvlkkiealelkNlrilr 57
++ k+ P++ l iE+ v+v +k ++ +++++ Nl+ +
tr|G1KB01|G1KB01_ANOCA 844 MEVYKNTPETVNLIIEVFVEVAHKQICYLGESKAMNLYEAC 884
6677899*****************************98666 PP
>> tr|H9GG55|H9GG55_ANOCA Protein arginine N-methyltransferase OS=Anolis carolinensis OX=28377 GN=PRMT7 PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 13.2 0.1 3e-05 0.046 2 58 .. 65 121 .. 64 128 .. 0.88
2 ? -3.1 0.0 3 4.6e+03 27 27 .. 424 424 .. 390 464 .. 0.43
Alignments for each domain:
== domain 1 score: 13.2 bits; conditional E-value: 3e-05
-EEEEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTTSS.EEEEES CS
Methyltransf_4 2 apvvleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkiealelkN.lrilrg 58
+ +vl+iG+G G +l+ +A + ++E+ +++ +++ k +e+++++N ++i+++
tr|H9GG55|H9GG55_ANOCA 65 RAIVLDIGTGTG-LLSMMAVTAGADFCYAVEVFKPMAETARKIVEKNGFSNkIKIINK 121
789*******99.68889******************************9996777765 PP
== domain 2 score: -3.1 bits; conditional E-value: 3
E CS
Methyltransf_4 27 n 27
+
tr|H9GG55|H9GG55_ANOCA 424 E 424
2 PP
>> tr|H9GHU6|H9GHU6_ANOCA Methylphosphate capping enzyme OS=Anolis carolinensis OX=28377 GN=MEPCE PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 11.8 0.0 8.4e-05 0.13 3 48 .. 407 452 .. 405 463 .. 0.89
2 ? -0.2 0.0 0.41 6.3e+02 99 150 .. 555 607 .. 553 613 .. 0.72
Alignments for each domain:
== domain 1 score: 11.8 bits; conditional E-value: 8.4e-05
EEEEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHC CS
Methyltransf_4 3 pvvleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkieal 48
+ vl++Gc G+f++ Akk ++G++i ++++ + ++i+++
tr|H9GHU6|H9GHU6_ANOCA 407 KEVLDVGCNVGHFTLSVAKKWGPARMVGLDIDGHLIHSARQNIRHY 452
679**********************************999999876 PP
== domain 2 score: -0.2 bits; conditional E-value: 0.41
HHHHHHHHEEEEEEEEEEES.HHHHHH..HHHHHHHCSTTEEESSCCCSCCTCHC CS
Methyltransf_4 99 llkelarvLkkgGvlelaTD.veeyae..emlkvleeeplferlskeeeleeepl 150
l k + r L++gG+l+l ++ y + + + ++++ f+r++ + ++ ++ l
tr|H9GHU6|H9GHU6_ANOCA 555 LFKRIYRHLRPGGILVLEPQaWSSYKKrkNLTETISRH--FNRIKLKPDQFPSYL 607
56788999********9988888886521456666666..888888877776655 PP
>> tr|H9GNU1|H9GNU1_ANOCA Methyltransferase like 5 OS=Anolis carolinensis OX=28377 GN=METTL5 PE=4 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 13.5 0.0 2.5e-05 0.039 2 77 .. 52 124 .. 51 136 .. 0.82
Alignments for each domain:
== domain 1 score: 13.5 bits; conditional E-value: 2.5e-05
-EEEEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTTSSEEEEES-CCCHHHHCS-TTSEEEEE CS
Methyltransf_4 2 apvvleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkiealelkNlrilrgdalkvllelledgslekif 77
+++v+++GcG G + + + +++G +i + ++ k++e+ el+N+ +++ + l++ +++ ++ +
tr|H9GNU1|H9GNU1_ANOCA 52 NKIVADLGCGCGVLSIGSSM-LGAGLCVGFDIDLDALDVFSKNAEEFELTNIDMIQCNV-CSLPDKMPK-IFDTVI 124
689*********99888665.56679********************************6.677777766.555555 PP
>> tr|H9G9N1|H9G9N1_ANOCA Protein arginine methyltransferase 1 OS=Anolis carolinensis OX=28377 GN=PRMT1 PE=3 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 10.6 0.1 0.00019 0.3 2 51 .. 88 135 .. 87 148 .. 0.79
Alignments for each domain:
== domain 1 score: 10.6 bits; conditional E-value: 0.00019
-EEEEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTTS CS
Methyltransf_4 2 apvvleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkiealelk 51
+vvl++G+G G + + A k k ++GiE + +++++++k ++a++l
tr|H9G9N1|H9G9N1_ANOCA 88 DKVVLDVGSGTGILCM-FAAKAGAKRVIGIECS-SISDYAVKIVKANKLD 135
5799*******97666.566667789*****96.5789999988888765 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (173 nodes)
Target sequences: 18528 (9796552 residues searched)
Passed MSV filter: 724 (0.039076); expected 370.6 (0.02)
Passed bias filter: 452 (0.0243955); expected 370.6 (0.02)
Passed Vit filter: 51 (0.00275259); expected 18.5 (0.001)
Passed Fwd filter: 12 (0.000647668); expected 0.2 (1e-05)
Initial search space (Z): 18528 [actual number of targets]
Domain search space (domZ): 12 [number of targets reported over threshold]
# CPU time: 0.18u 0.01s 00:00:00.19 Elapsed: 00:00:00.07
# Mc/sec: 24211.48
//
[ok]