# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/Methyltransf_4.hmm.txt
# target sequence database: proteomes/Ciona_savignyi.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: Methyltransf_4 [M=173]
Accession: PF02390.16
Description: Putative methyltransferase
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
7.8e-58 194.1 0.0 9.5e-58 193.9 0.0 1.1 1 tr|H2YSN6|H2YSN6_CIOSA tRNA (guanine-N(7)-)-methyltransferas
1.3e-05 24.1 0.2 3.7e-05 22.6 0.0 1.8 2 tr|H2YWU1|H2YWU1_CIOSA Uncharacterized protein OS=Ciona savi
0.0022 16.9 0.0 0.0057 15.5 0.0 1.7 2 tr|H2YNF4|H2YNF4_CIOSA Protein-lysine N-methyltransferase OS
------ inclusion threshold ------
0.014 14.2 0.0 0.27 10.1 0.0 2.3 2 tr|H2YJS4|H2YJS4_CIOSA Uncharacterized protein OS=Ciona savi
0.017 14.0 0.0 0.045 12.6 0.0 1.8 1 tr|H2YL80|H2YL80_CIOSA Uncharacterized protein OS=Ciona savi
0.042 12.7 0.1 0.083 11.7 0.1 1.5 1 tr|H2Z8Q4|H2Z8Q4_CIOSA Uncharacterized protein OS=Ciona savi
0.042 12.7 0.0 0.8 8.5 0.0 2.3 2 tr|H2Y8E5|H2Y8E5_CIOSA Uncharacterized protein OS=Ciona savi
0.1 11.4 0.0 0.37 9.6 0.0 1.9 3 tr|H2YGP5|H2YGP5_CIOSA Uncharacterized protein OS=Ciona savi
Domain annotation for each sequence (and alignments):
>> tr|H2YSN6|H2YSN6_CIOSA tRNA (guanine-N(7)-)-methyltransferase OS=Ciona savignyi OX=51511 PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 193.9 0.0 6.5e-61 9.5e-58 2 172 .. 67 245 .. 66 246 .. 0.98
Alignments for each domain:
== domain 1 score: 193.9 bits; conditional E-value: 6.5e-61
-EEEEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHC........TTSSEEEEES-CCCHHHHCS-TTSEEEEEEES CS
Methyltransf_4 2 apvvleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkieal........elkNlrilrgdalkvllelledgslekifilF 80
++ vl+iGcG+G++l+al+k P++++lG+Eirvkv+++v ++i+al +++N++++r++a+k+l++++++g+l+k+filF
tr|H2YSN6|H2YSN6_CIOSA 67 KVEVLDIGCGYGGLLIALSKLLPETLILGLEIRVKVSEYVQERIQALrkadtenkNFQNVACIRTNAMKYLPNFFSKGQLKKMFILF 153
5789*********************************************************************************** PP
-----SGGGGGGSTTSHHHHHHHHHHEEEEEEEEEEESHHHHHHHHHHHHHCSTTEEESSCCCSCCTCHCHHCCCSSTTCCCCCCTT CS
Methyltransf_4 81 PDPwfKkrhhKrRllqpellkelarvLkkgGvlelaTDveeyaeemlkvleeeplferlskeeeleeeplsvlriatkyeqkvqskg 167
PDP+fKk++hK+R+++p+ll+e+a++L +gG+l+++TDv e++e+m+ ++ e+plfer+s+++ + + + + ++t++++kv+++
tr|H2YSN6|H2YSN6_CIOSA 154 PDPHFKKQKHKWRIVSPTLLAEYAYILCQGGSLYTITDVLEVHEWMVRHITEHPLFERVSESDLSDDVCYKAMFVSTEEGRKVTRNS 240
**************************************************************************************9 PP
SS-EE CS
Methyltransf_4 168 keiye 172
+++y
tr|H2YSN6|H2YSN6_CIOSA 241 GDKYP 245
99986 PP
>> tr|H2YWU1|H2YWU1_CIOSA Uncharacterized protein OS=Ciona savignyi OX=51511 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? -2.1 0.1 1 1.5e+03 83 111 .. 199 227 .. 176 237 .. 0.77
2 ! 22.6 0.0 2.6e-08 3.7e-05 3 68 .. 382 446 .. 380 450 .. 0.93
Alignments for each domain:
== domain 1 score: -2.1 bits; conditional E-value: 1
---SGGGGGGSTTSHHHHHHHHHHEEEEE CS
Methyltransf_4 83 PwfKkrhhKrRllqpellkelarvLkkgG 111
P +Kk + ++R+++ + l l++v +g
tr|H2YWU1|H2YWU1_CIOSA 199 PPNKKIKARKRVIKTNDLPPLEHVFTEGV 227
77888899999999888888877777654 PP
== domain 2 score: 22.6 bits; conditional E-value: 2.6e-08
EEEEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTTSSEEEEES-CCCHHHHCS CS
Methyltransf_4 3 pvvleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkiealelkNlrilrgdalkvllell 68
v+++ ++G G++ + lA P+++++ +E ++++++++ ++i+ l+lkN+ + + + l+++++ +
tr|H2YWU1|H2YWU1_CIOSA 382 DVIVDFCSGGGHVGIVLAYLLPSCKVILVENKEESLDRAYQRIQTLKLKNIMLYQCN-LDQFSKDF 446
5899***************************************************99.58887766 PP
>> tr|H2YNF4|H2YNF4_CIOSA Protein-lysine N-methyltransferase OS=Ciona savignyi OX=51511 PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 15.5 0.0 3.9e-06 0.0057 4 53 .. 62 110 .. 59 123 .. 0.89
2 ? -2.3 0.0 1.1 1.7e+03 121 146 .. 172 197 .. 169 208 .. 0.70
Alignments for each domain:
== domain 1 score: 15.5 bits; conditional E-value: 3.9e-06
EEEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTTSSE CS
Methyltransf_4 4 vvleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkiealelkNl 53
+l++GcG+G +l+alAk kn++Gi+ ++ ++ + + ++++++N+
tr|H2YNF4|H2YNF4_CIOSA 62 RILDVGCGNGLMLLALAKL-GYKNLVGIDYCQSALDLASAVFRKENFENV 110
589**************97.57899*********************9998 PP
== domain 2 score: -2.3 bits; conditional E-value: 1.1
HHHHHHHHHHHCSTTEEESSCCCSCC CS
Methyltransf_4 121 eyaeemlkvleeeplferlskeeele 146
y e+m+ +++ f+++s ++ +
tr|H2YNF4|H2YNF4_CIOSA 172 SYIENMARIMNHSSIFVITSCNWTAN 197
57888888888888888776665444 PP
>> tr|H2YJS4|H2YJS4_CIOSA Uncharacterized protein OS=Ciona savignyi OX=51511 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 1.8 0.0 0.063 92 4 19 .. 82 97 .. 79 110 .. 0.85
2 ? 10.1 0.0 0.00019 0.27 94 121 .. 159 186 .. 158 234 .. 0.78
Alignments for each domain:
== domain 1 score: 1.8 bits; conditional E-value: 0.063
EEEEET-TTSHHHHHH CS
Methyltransf_4 4 vvleiGcGkGeflval 19
+ l+iG G G++ +al
tr|H2YJS4|H2YJS4_CIOSA 82 TALDIGAGTGQMAIAL 97
579********99987 PP
== domain 2 score: 10.1 bits; conditional E-value: 0.00019
TTSHHHHHHHHHHEEEEEEEEEEESHHH CS
Methyltransf_4 94 llqpellkelarvLkkgGvlelaTDvee 121
l+qpe l ++arv k+gG+l++ T +
tr|H2YJS4|H2YJS4_CIOSA 159 LIQPECLPDMARVVKPGGQLYFTTRATD 186
79*******************9875443 PP
>> tr|H2YL80|H2YL80_CIOSA Uncharacterized protein OS=Ciona savignyi OX=51511 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 12.6 0.0 3.1e-05 0.045 2 56 .. 83 138 .. 82 162 .. 0.80
Alignments for each domain:
== domain 1 score: 12.6 bits; conditional E-value: 3.1e-05
-EEEEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHC..TTSSEEEE CS
Methyltransf_4 2 apvvleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkieal..elkNlril 56
+pvvl++GcGkG+ +++ k++P+ ++ ++ +++v ++ ++ + l + +N +i+
tr|H2YL80|H2YL80_CIOSA 83 HPVVLDLGCGKGGDILKWDKARPNH-LICTDLAETSVSQCKDRYALLkkRHRNKQIF 138
79*********************86.5788999999999998877654455665555 PP
>> tr|H2Z8Q4|H2Z8Q4_CIOSA Uncharacterized protein OS=Ciona savignyi OX=51511 PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 11.7 0.1 5.8e-05 0.083 2 44 .. 67 107 .. 66 116 .. 0.74
Alignments for each domain:
== domain 1 score: 11.7 bits; conditional E-value: 5.8e-05
-EEEEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHH CS
Methyltransf_4 2 apvvleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkk 44
++vvl++GcG G + + A k +++GiE ++ +v+++ k
tr|H2Z8Q4|H2Z8Q4_CIOSA 67 NKVVLDVGCGTGVL-SMFAAKAGAAKVIGIECSS-IVDYAKKI 107
689********965.556666777899****864.56666555 PP
>> tr|H2Y8E5|H2Y8E5_CIOSA Uncharacterized protein OS=Ciona savignyi OX=51511 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 8.5 0.0 0.00055 0.8 5 48 .. 74 118 .. 70 152 .. 0.82
2 ? 1.4 0.0 0.083 1.2e+02 97 116 .. 165 184 .. 163 201 .. 0.85
Alignments for each domain:
== domain 1 score: 8.5 bits; conditional E-value: 0.00055
EEEET-TTSHHHHHHHHH.STTSEEEEEES-HHHHHHHHHHHHHC CS
Methyltransf_4 5 vleiGcGkGeflvalAkk.nPdknflGiEirvkvvakvlkkieal 48
+l++G+G+G+ alAk Pd + G+++ + +a ++k++e +
tr|H2Y8E5|H2Y8E5_CIOSA 74 LLDLGSGSGRDCFALAKLvGPDGFVTGVDMTDEQLAVANKHVEYH 118
79**************9637*****************99999877 PP
== domain 2 score: 1.4 bits; conditional E-value: 0.083
HHHHHHHHHHEEEEEEEEEE CS
Methyltransf_4 97 pellkelarvLkkgGvlela 116
+++lke+ rvLk gG+l++
tr|H2Y8E5|H2Y8E5_CIOSA 165 EAVLKEAYRVLKYGGELYFS 184
67899************984 PP
>> tr|H2YGP5|H2YGP5_CIOSA Uncharacterized protein OS=Ciona savignyi OX=51511 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 9.6 0.0 0.00026 0.37 4 54 .. 33 90 .. 30 112 .. 0.74
2 ? -2.9 0.0 1.8 2.7e+03 98 114 .. 124 140 .. 122 145 .. 0.81
3 ? -2.3 0.0 1.2 1.8e+03 97 137 .. 234 278 .. 231 292 .. 0.57
Alignments for each domain:
== domain 1 score: 9.6 bits; conditional E-value: 0.00026
EEEEET-TTSHHHHHHHHHSTTS.EEEEEES-HHHHHHHHHHHHHC......TTSSEE CS
Methyltransf_4 4 vvleiGcGkGeflvalAkknPdk.nflGiEirvkvvakvlkkieal......elkNlr 54
v+++GcG+G+ a+A+ ++ +++G+++ ++ ++ + k e + + +N+r
tr|H2YGP5|H2YGP5_CIOSA 33 KVVDLGCGSGRDCYAIAQLVGENgEVIGVDMTKEQLDIARKYEEYHrvkfgfKESNVR 90
589***************99876489*****999887665544444444444444554 PP
== domain 2 score: -2.9 bits; conditional E-value: 1.8
HHHHHHHHHEEEEEEEE CS
Methyltransf_4 98 ellkelarvLkkgGvle 114
++ ke+ r+Lk gG+++
tr|H2YGP5|H2YGP5_CIOSA 124 AVFKEVFRILKTGGEFY 140
567899999*****987 PP
== domain 3 score: -2.3 bits; conditional E-value: 1.2
HHHHHHHHHHEEEEEEEEEEES....HHHHHHHHHHHHHCSTTEE CS
Methyltransf_4 97 pellkelarvLkkgGvlelaTD....veeyaeemlkvleeeplfe 137
+ ++k+ +++Lk + ++aTD v ++ l ++ p+fe
tr|H2YGP5|H2YGP5_CIOSA 234 KGTIKDNHEMLKFDRNSTFATDdttqVDGVTAATLRSTRFSPHFE 278
556677777777777778888844444444444444444444444 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (173 nodes)
Target sequences: 11592 (4231397 residues searched)
Passed MSV filter: 426 (0.0367495); expected 231.8 (0.02)
Passed bias filter: 279 (0.0240683); expected 231.8 (0.02)
Passed Vit filter: 34 (0.00293306); expected 11.6 (0.001)
Passed Fwd filter: 8 (0.000690131); expected 0.1 (1e-05)
Initial search space (Z): 11592 [actual number of targets]
Domain search space (domZ): 8 [number of targets reported over threshold]
# CPU time: 0.08u 0.00s 00:00:00.08 Elapsed: 00:00:00.04
# Mc/sec: 18300.79
//
[ok]