# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/Methyltransf_4.hmm.txt
# target sequence database: proteomes/Monodelphis_domestica.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: Methyltransf_4 [M=173]
Accession: PF02390.16
Description: Putative methyltransferase
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
8.9e-59 198.1 0.0 1.1e-58 197.7 0.0 1.1 1 tr|H9H7Z1|H9H7Z1_MONDO tRNA (guanine-N(7)-)-methyltransferas
4.3e-06 26.6 0.3 1.4e-05 24.9 0.1 1.8 2 tr|F6S9Y2|F6S9Y2_MONDO tRNA methyltransferase 2 homolog A OS
9.7e-05 22.1 0.0 0.00015 21.5 0.0 1.2 1 tr|F7D1V9|F7D1V9_MONDO Uncharacterized protein OS=Monodelphi
0.0022 17.7 0.1 0.0032 17.2 0.1 1.2 1 tr|F6ZXU0|F6ZXU0_MONDO Methyltransferase like 5 OS=Monodelph
0.0031 17.2 0.0 0.0054 16.4 0.0 1.3 1 tr|F6ZAN7|F6ZAN7_MONDO Glutathione S-transferase C-terminal
------ inclusion threshold ------
0.013 15.2 0.3 0.39 10.4 0.0 2.7 2 tr|F6Z8P9|F6Z8P9_MONDO Exportin 4 OS=Monodelphis domestica O
0.028 14.1 0.0 0.047 13.4 0.0 1.4 1 tr|F6SAW9|F6SAW9_MONDO EEF1A lysine methyltransferase 2 OS=M
0.051 13.3 0.0 0.18 11.5 0.0 1.8 2 tr|F7B9I4|F7B9I4_MONDO HemK methyltransferase family member
0.2 11.4 0.1 3.4 7.4 0.1 2.3 2 tr|F7FNT7|F7FNT7_MONDO NOP2/Sun RNA methyltransferase family
0.29 10.8 0.0 0.68 9.6 0.0 1.6 1 tr|F6R6T5|F6R6T5_MONDO Methylphosphate capping enzyme OS=Mon
Domain annotation for each sequence (and alignments):
>> tr|H9H7Z1|H9H7Z1_MONDO tRNA (guanine-N(7)-)-methyltransferase OS=Monodelphis domestica OX=13616 GN=METTL1 PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 197.7 0.0 5.4e-62 1.1e-58 2 172 .. 71 247 .. 70 248 .. 0.98
Alignments for each domain:
== domain 1 score: 197.7 bits; conditional E-value: 5.4e-62
-EEEEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHC......TTSSEEEEES-CCCHHHHCS-TTSEEEEEEES-- CS
Methyltransf_4 2 apvvleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkieal......elkNlrilrgdalkvllelledgslekifilFPD 82
++ +++iGcG+G++lv+l++++P++++lG+Eirvkv+++v ++i+al +++N+++lr++a+k+l++++++g+l+k+f+lFPD
tr|H9H7Z1|H9H7Z1_MONDO 71 QVEFADIGCGYGGLLVELSPMFPNTLILGLEIRVKVSDYVQDRIRALrstsggGFQNIACLRSNAMKHLPNFFHKGQLTKMFFLFPD 157
6789*********************************************************************************** PP
---SGGGGGGSTTSHHHHHHHHHHEEEEEEEEEEESHHHHHHHHHHHHHCSTTEEESSCCCSCCTCHCHHCCCSSTTCCCCCCTTSS CS
Methyltransf_4 83 PwfKkrhhKrRllqpellkelarvLkkgGvlelaTDveeyaeemlkvleeeplferlskeeeleeeplsvlriatkyeqkvqskgke 169
P+fK+ +hK+R+++p+ll+e+a+vL+ gG+++++TDv +++ ++++++ee+plfer+ +ee + ++++ +l +t++++kv ++g++
tr|H9H7Z1|H9H7Z1_MONDO 158 PHFKRTKHKWRIISPTLLAEYAYVLRIGGLVYTITDVMDLHSWICTHFEEHPLFERVPQEELVDDPIVGHLGTSTEEGKKVLRNGGK 244
*************************************************************************************99 PP
-EE CS
Methyltransf_4 170 iye 172
+
tr|H9H7Z1|H9H7Z1_MONDO 245 NFP 247
886 PP
>> tr|F6S9Y2|F6S9Y2_MONDO tRNA methyltransferase 2 homolog A OS=Monodelphis domestica OX=13616 GN=TRMT2A PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? -1.7 0.0 0.98 2.1e+03 60 90 .. 117 149 .. 114 150 .. 0.86
2 ! 24.9 0.1 6.4e-09 1.4e-05 4 70 .. 447 511 .. 444 521 .. 0.82
Alignments for each domain:
== domain 1 score: -1.7 bits; conditional E-value: 0.98
CCCHHHHCS-TTSEEEEEEES-..----SGGGG CS
Methyltransf_4 60 alkvllelledgslekifilFP..DPwfKkrhh 90
a+kvl+ +l +g++ i++ P DP Kkr++
tr|F6S9Y2|F6S9Y2_MONDO 117 AMKVLHGALWKGRCLSIRLAKPkaDPMAKKRKR 149
899999999999999999998877999999985 PP
== domain 2 score: 24.9 bits; conditional E-value: 6.4e-09
EEEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTTSSEEEEES-CCCHHHHCS-T CS
Methyltransf_4 4 vvleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkiealelkNlrilrgdalkvllelled 70
+vl+++cG G++ + lA+ k ++GiE+ ++ v+ + +++ + l N++ ++g a +++++l++
tr|F6S9Y2|F6S9Y2_MONDO 447 TVLDVCCGTGTIGLSLAQ--TVKRVIGIELCQEAVEDARVNAKMNALDNIEFHCGKAEDLVPSLMSS 511
799*******98777776..5799*********************************7776666554 PP
>> tr|F7D1V9|F7D1V9_MONDO Uncharacterized protein OS=Monodelphis domestica OX=13616 GN=METTL26 PE=4 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 21.5 0.0 6.9e-08 0.00015 4 54 .. 28 78 .. 25 86 .. 0.94
Alignments for each domain:
== domain 1 score: 21.5 bits; conditional E-value: 6.9e-08
EEEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTTSSEE CS
Methyltransf_4 4 vvleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkiealelkNlr 54
vle+ +G+G+++ Ak++P++ + E+ ++ ++ + + i++++l+N+r
tr|F7D1V9|F7D1V9_MONDO 28 QVLEVASGSGQHVTYFAKAFPKVVWQPTEVDRQCLNSISALIKKEQLQNVR 78
689**********************************************97 PP
>> tr|F6ZXU0|F6ZXU0_MONDO Methyltransferase like 5 OS=Monodelphis domestica OX=13616 GN=METTL5 PE=4 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 17.2 0.1 1.5e-06 0.0032 2 79 .. 49 123 .. 48 133 .. 0.85
Alignments for each domain:
== domain 1 score: 17.2 bits; conditional E-value: 1.5e-06
-EEEEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTTSSEEEEES-CCCHHHHCS-TTSEEEEEEE CS
Methyltransf_4 2 apvvleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkiealelkNlrilrgdalkvllelledgslekifil 79
++v+ ++GcG G + + A +++G +i ++ ++ +k++++ el+N+ +++ + l+e +++ s++ i ++
tr|F6ZXU0|F6ZXU0_MONDO 49 NKVIGDLGCGCGMLSIGAAML-GAGLCVGFDIDEDALEIFNKNVKEFELTNIDMIQCNV-CSLSETISK-SFDTIIMN 123
577889******999987765.5679********************************6.899999998.88888886 PP
>> tr|F6ZAN7|F6ZAN7_MONDO Glutathione S-transferase C-terminal domain containing OS=Monodelphis domestica OX=13616 GN=G
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 16.4 0.0 2.6e-06 0.0054 4 66 .. 432 493 .. 429 498 .. 0.92
Alignments for each domain:
== domain 1 score: 16.4 bits; conditional E-value: 2.6e-06
EEEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTTSSEEEEES-CCCHHHH CS
Methyltransf_4 4 vvleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkiealelkNlrilrgdalkvlle 66
++++ ++G G++ + lA+ P++++l iE ++ ++ ++ k+ ++l+l+N+ ++ + l++++
tr|F6ZAN7|F6ZAN7_MONDO 432 IIVDFCSGGGHVGIVLAHLLPSCQVLLIENKELSLVRAKKRSDDLGLTNIWFIQAN-LDYFTG 493
799***************************************************99.477765 PP
>> tr|F6Z8P9|F6Z8P9_MONDO Exportin 4 OS=Monodelphis domestica OX=13616 GN=XPO4 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 10.4 0.0 0.00019 0.39 94 151 .. 746 811 .. 687 824 .. 0.69
2 ? 1.5 0.1 0.099 2.1e+02 17 57 .. 846 886 .. 841 901 .. 0.86
Alignments for each domain:
== domain 1 score: 10.4 bits; conditional E-value: 0.00019
TTSHHHHHHHHHHEEEEEEEEEEES.........HHHHHHHHHHHHHCSTTEEESSCCCSCCTCHCH CS
Methyltransf_4 94 llqpellkelarvLkkgGvlelaTD.........veeyaeemlkvleeeplferlskeeeleeepls 151
ll++ + l+++L+ gG+ ++ TD +++++++ l+v+++e +f+++++eee+++e++
tr|F6Z8P9|F6Z8P9_MONDO 746 LLSSSVQRTLMKALVLGGFAHMDTDtkqqywtevLQPLQQRFLNVINQE-NFQQICQEEEVKQEITA 811
6677777889***************977776555556666666666666.78888887777776665 PP
== domain 2 score: 1.5 bits; conditional E-value: 0.099
HHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTTSSEEEEE CS
Methyltransf_4 17 valAkknPdknflGiEirvkvvakvlkkiealelkNlrilr 57
++ k+ P++ l iE+ v+v +k ++ +++++ Nl+ +
tr|F6Z8P9|F6Z8P9_MONDO 846 MEVYKNTPETVNLIIEVFVEVAHKQICYLGESKAMNLYEAC 886
6677899*****************************98666 PP
>> tr|F6SAW9|F6SAW9_MONDO EEF1A lysine methyltransferase 2 OS=Monodelphis domestica OX=13616 GN=EEF1AKMT2 PE=3 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 13.4 0.0 2.2e-05 0.047 4 60 .. 65 120 .. 63 175 .. 0.79
Alignments for each domain:
== domain 1 score: 13.4 bits; conditional E-value: 2.2e-05
EEEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTTSSEEEEES-C CS
Methyltransf_4 4 vvleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkiealelkNlrilrgda 60
vl+iG+G+G flv+lAk ++ Gi+ ++ + ie+++++N+ l+ +
tr|F6SAW9|F6SAW9_MONDO 65 SVLDIGTGNGIFLVELAKLG-YSDITGIDYCPLAIQLSGRIIEKEGFSNIIKLQVED 120
689**************975.567889999999999999999999999998887764 PP
>> tr|F7B9I4|F7B9I4_MONDO HemK methyltransferase family member 1 OS=Monodelphis domestica OX=13616 GN=HEMK1 PE=4 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 11.5 0.0 8.6e-05 0.18 3 60 .. 172 230 .. 170 238 .. 0.90
2 ? -1.6 0.0 0.92 2e+03 98 127 .. 288 319 .. 285 325 .. 0.81
Alignments for each domain:
== domain 1 score: 11.5 bits; conditional E-value: 8.6e-05
EEEEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTTSS.EEEEES-C CS
Methyltransf_4 3 pvvleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkiealelkN.lrilrgda 60
p++l+++cG+G + + l k + ++++++ ++ v+ +++++l+l+ ++i+r+d
tr|F7B9I4|F7B9I4_MONDO 172 PLILDVCCGSGAIALSLLSKLTQSRVVAVDKGEEAVQLTRENAQRLHLEDrIQIVRHDI 230
799***********************************999999998874488888886 PP
== domain 2 score: -1.6 bits; conditional E-value: 0.92
HHHHHHHHHEEEEEEEEEEES..HHHHHHHHH CS
Methyltransf_4 98 ellkelarvLkkgGvlelaTD..veeyaeeml 127
e+l+++ Lk +G++ l D ++e+ e+ l
tr|F7B9I4|F7B9I4_MONDO 288 EILSQAPMLLKDSGSIFLEVDprHPELVEKWL 319
678888899*********99988888777665 PP
>> tr|F7FNT7|F7FNT7_MONDO NOP2/Sun RNA methyltransferase family member 6 OS=Monodelphis domestica OX=13616 GN=NSUN6 PE=
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 7.4 0.1 0.0016 3.4 5 65 .. 238 299 .. 235 305 .. 0.85
2 ? 1.1 0.0 0.13 2.7e+02 96 137 .. 349 390 .. 348 402 .. 0.72
Alignments for each domain:
== domain 1 score: 7.4 bits; conditional E-value: 0.0016
EEEET-TTSHHHHHHHH.HSTTSEEEEEES-HHHHHHHHHHHHHCTTSSEEEEES-CCCHHH CS
Methyltransf_4 5 vleiGcGkGeflvalAk.knPdknflGiEirvkvvakvlkkiealelkNlrilrgdalkvll 65
+l+++ + G+ + ++A ++ + +++++++ + v+k+ ++++ l+l+ +r ++ + +k l
tr|F7FNT7|F7FNT7_MONDO 238 ILDMCAAPGGKTTHIAAlMRDQGEVIAMDKIPSKVEKIKQNAALLQLNCIRAFCCNGTKALG 299
688999999888888761556679********************************999884 PP
== domain 2 score: 1.1 bits; conditional E-value: 0.13
SHHHHHHHHHHEEEEEEEEEEESHHHHHHHHHHHHHCSTTEE CS
Methyltransf_4 96 qpellkelarvLkkgGvlelaTDveeyaeemlkvleeeplfe 137
q++l + + + Lk+gGvl+ T +ae+ +v+ + + f
tr|F7FNT7|F7FNT7_MONDO 349 QRKLFTVAVQLLKPGGVLVYSTCTITLAENEEQVAWALTAFP 390
6778888899**********9997777777666655555554 PP
>> tr|F6R6T5|F6R6T5_MONDO Methylphosphate capping enzyme OS=Monodelphis domestica OX=13616 GN=MEPCE PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 9.6 0.0 0.00032 0.68 4 54 .. 434 484 .. 431 489 .. 0.88
Alignments for each domain:
== domain 1 score: 9.6 bits; conditional E-value: 0.00032
EEEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTTSSEE CS
Methyltransf_4 4 vvleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkiealelkNlr 54
vl++Gc G++++ +A k ++G++i ++++ + ++i+++ + lr
tr|F6R6T5|F6R6T5_MONDO 434 DVLDLGCNVGHLTLSIACKWGPARVVGVDIDARLIHSARQNIRHYLSEELR 484
689*************************************99988666555 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (173 nodes)
Target sequences: 21272 (11266248 residues searched)
Passed MSV filter: 829 (0.0389714); expected 425.4 (0.02)
Passed bias filter: 481 (0.0226119); expected 425.4 (0.02)
Passed Vit filter: 55 (0.00258556); expected 21.3 (0.001)
Passed Fwd filter: 10 (0.000470102); expected 0.2 (1e-05)
Initial search space (Z): 21272 [actual number of targets]
Domain search space (domZ): 10 [number of targets reported over threshold]
# CPU time: 0.17u 0.01s 00:00:00.18 Elapsed: 00:00:00.07
# Mc/sec: 27843.73
//
[ok]