# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/Methyltransf_4.hmm.txt
# target sequence database: proteomes/Petromyzon_marinus.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: Methyltransf_4 [M=173]
Accession: PF02390.16
Description: Putative methyltransferase
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
7.3e-33 113.1 0.1 8.1e-33 112.9 0.1 1.0 1 tr|S4R6J3|S4R6J3_PETMA tRNA (guanine(46)-N(7))-methyltransfe
2.9e-05 23.2 0.0 0.026 13.6 0.0 2.8 3 tr|S4R4I3|S4R4I3_PETMA Phosphoethanolamine methyltransferase
0.00036 19.6 0.0 0.0024 16.9 0.0 2.2 1 tr|S4RJ28|S4RJ28_PETMA Zgc:162396 OS=Petromyzon marinus OX=7
0.00037 19.6 0.0 0.0023 17.0 0.0 2.0 1 tr|S4RNK8|S4RNK8_PETMA Zgc:162396 OS=Petromyzon marinus OX=7
0.00043 19.4 0.0 0.00062 18.9 0.0 1.2 1 tr|S4R931|S4R931_PETMA Zgc:103625 OS=Petromyzon marinus OX=7
0.0038 16.3 0.0 0.0059 15.7 0.0 1.2 1 tr|S4RMF5|S4RMF5_PETMA HemK methyltransferase family member
0.0052 15.9 0.0 0.85 8.7 0.0 2.6 2 tr|S4RMG0|S4RMG0_PETMA Phosphoethanolamine methyltransferase
0.0073 15.4 0.0 0.16 11.0 0.0 2.2 2 tr|S4RFT9|S4RFT9_PETMA Zgc:162396 OS=Petromyzon marinus OX=7
------ inclusion threshold ------
0.036 13.1 0.4 0.11 11.5 0.0 2.1 3 tr|S4RRK5|S4RRK5_PETMA Methyltransferase-like protein OS=Pet
0.041 13.0 0.1 2.8 7.0 0.0 2.3 2 tr|S4RQZ8|S4RQZ8_PETMA THUMP domain containing 2 OS=Petromyz
0.062 12.4 0.0 0.12 11.4 0.0 1.5 1 tr|S4R827|S4R827_PETMA Protein-L-isoaspartate (D-aspartate)
0.081 12.0 0.0 0.11 11.6 0.0 1.2 1 tr|S4RFJ6|S4RFJ6_PETMA Uncharacterized protein OS=Petromyzon
0.092 11.8 0.0 0.21 10.7 0.0 1.6 1 tr|S4RXY4|S4RXY4_PETMA Methyltransferase-like protein OS=Pet
Domain annotation for each sequence (and alignments):
>> tr|S4R6J3|S4R6J3_PETMA tRNA (guanine(46)-N(7))-methyltransferase OS=Petromyzon marinus OX=7757 PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 112.9 0.1 7.8e-36 8.1e-33 72 172 .. 1 101 [. 1 102 [. 0.98
Alignments for each domain:
== domain 1 score: 112.9 bits; conditional E-value: 7.8e-36
SEEEEEEES-----SGGGGGGSTTSHHHHHHHHHHEEEEEEEEEEESHHHHHHHHHHHHHCSTTEEESSCCCSCCTCHCHHCCCSST CS
Methyltransf_4 72 slekifilFPDPwfKkrhhKrRllqpellkelarvLkkgGvlelaTDveeyaeemlkvleeeplferlskeeeleeeplsvlriatk 158
+l+k+f+lFPDP+fKk +hK+R+++p+ll+e+a++L++gG+++++TDv e++++mlk++ee+plf+ + +e + + ++s+l + t+
tr|S4R6J3|S4R6J3_PETMA 1 QLSKMFFLFPDPHFKKTKHKWRIISPTLLAEYAYILRPGGLVYTITDVHEVHRWMLKHFEEHPLFHHVPLDELEDDVIVSQLGECTE 87
699************************************************************************************ PP
TCCCCCCTTSS-EE CS
Methyltransf_4 159 yeqkvqskgkeiye 172
+++kv+++g+e++
tr|S4R6J3|S4R6J3_PETMA 88 EGKKVTRNGGEKFT 101
**********9986 PP
>> tr|S4R4I3|S4R4I3_PETMA Phosphoethanolamine methyltransferase OS=Petromyzon marinus OX=7757 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 6.5 0.0 0.0037 3.9 4 77 .. 53 119 .. 50 122 .. 0.68
2 ? -3.7 0.0 5.3 5.5e+03 99 115 .. 135 151 .. 134 152 .. 0.86
3 ! 13.6 0.0 2.5e-05 0.026 4 50 .. 286 331 .. 283 355 .. 0.83
Alignments for each domain:
== domain 1 score: 6.5 bits; conditional E-value: 0.0037
EEEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTTSSEEEEES-CCCHHHHCS-TTSEEEEE CS
Methyltransf_4 4 vvleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkiealelkNlrilrgdalkvllelledgslekif 77
vle+G G G+f+ +lAk+ +++ +++ ++ ++k + +++ N++ l+ d ++l ++++s++ if
tr|S4R4I3|S4R4I3_PETMA 53 KVLELGAGIGRFTGHLAKQARHVT--AVDFMQTFLDKN--RELNSDHVNIKFLQADV-TQL--QFPENSFDVIF 119
689****************87765..666666666652..22233556777777774.555..56666666665 PP
== domain 2 score: -3.7 bits; conditional E-value: 5.3
HHHHHHHHEEEEEEEEE CS
Methyltransf_4 99 llkelarvLkkgGvlel 115
l++ + r L++gG l +
tr|S4R4I3|S4R4I3_PETMA 135 LVNSMLRWLRPGGHLFF 151
6899999******9987 PP
== domain 3 score: 13.6 bits; conditional E-value: 2.5e-05
EEEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTT CS
Methyltransf_4 4 vvleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkiealel 50
vl++GcG G+ +Ak++ ++++lG+++++++v+ +++++ ++
tr|S4R4I3|S4R4I3_PETMA 286 KVLDVGCGIGGGNFYMAKAF-KVDVLGMDLSSNMVEIAMERATEDST 331
589***************98.89*****************9988755 PP
>> tr|S4RJ28|S4RJ28_PETMA Zgc:162396 OS=Petromyzon marinus OX=7757 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 16.9 0.0 2.3e-06 0.0024 5 85 .. 2 74 .. 1 145 [. 0.81
Alignments for each domain:
== domain 1 score: 16.9 bits; conditional E-value: 2.3e-06
EEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTTSSEEEEES-CCCHHHHCS-TTSEEEEEEES----- CS
Methyltransf_4 5 vleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkiealelkNlrilrgdalkvllelledgslekifilFPDPwf 85
++iGcG+G+ + lA ++n+lGi+++ + ++++ ++a++ N+ ++ g a ++l + dgs++ + + + wf
tr|S4RJ28|S4RJ28_PETMA 2 AVDIGCGSGQGTEILASF--STNVLGIDVSPSQIEEA---MHAKHPDNISYIVGPA-ETL--PVDDGSVSLLTAFVSAHWF 74
69**********999975..789*******9987765...6789999****99999.887..4667777766666666665 PP
>> tr|S4RNK8|S4RNK8_PETMA Zgc:162396 OS=Petromyzon marinus OX=7757 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 17.0 0.0 2.2e-06 0.0023 5 86 .. 2 75 .. 1 145 [. 0.81
Alignments for each domain:
== domain 1 score: 17.0 bits; conditional E-value: 2.2e-06
EEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTTSSEEEEES-CCCHHHHCS-TTSEEEEEEES-----S CS
Methyltransf_4 5 vleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkiealelkNlrilrgdalkvllelledgslekifilFPDPwfK 86
+++GcG+G+ + lA +++lGi+++ + ++++ ++a++l N+ ++ g a ++l + dgs++ + + + wf
tr|S4RNK8|S4RNK8_PETMA 2 AVDVGCGSGQGTELLASIS--TKVLGIDVSPSQIEEA---MRAKHLDNITYIVGPA-ETL--PVDDGSVSLLTAFVSAHWFD 75
69*************9875..789******9987765...67899********999.888..46777777776666666654 PP
>> tr|S4R931|S4R931_PETMA Zgc:103625 OS=Petromyzon marinus OX=7757 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 18.9 0.0 6e-07 0.00062 5 54 .. 30 79 .. 26 85 .. 0.95
Alignments for each domain:
== domain 1 score: 18.9 bits; conditional E-value: 6e-07
EEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTTSSEE CS
Methyltransf_4 5 vleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkiealelkNlr 54
le+ +G+G+++v+lA ++P+ ++ E++ ++ + + + ++a +l+N++
tr|S4R931|S4R931_PETMA 30 ALEVASGSGQHVVHLARAFPHLTWQPSELEASSFQSISAYARATQLQNVL 79
68**********************************************85 PP
>> tr|S4RMF5|S4RMF5_PETMA HemK methyltransferase family member 1 OS=Petromyzon marinus OX=7757 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 15.7 0.0 5.7e-06 0.0059 5 51 .. 62 108 .. 60 121 .. 0.91
Alignments for each domain:
== domain 1 score: 15.7 bits; conditional E-value: 5.7e-06
EEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTTS CS
Methyltransf_4 5 vleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkiealelk 51
vl+iGcG+G + +a+ + P ++++++++ + va + +++e+l l+
tr|S4RMF5|S4RMF5_PETMA 62 VLDIGCGSGAISLAILSASPLASCVAVDKSADAVALARENAEDLSLQ 108
79*********************************999999888765 PP
>> tr|S4RMG0|S4RMG0_PETMA Phosphoethanolamine methyltransferase OS=Petromyzon marinus OX=7757 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 4.5 0.0 0.016 16 4 72 .. 50 111 .. 47 119 .. 0.68
2 ! 8.7 0.0 0.00082 0.85 4 73 .. 284 349 .. 281 354 .. 0.82
Alignments for each domain:
== domain 1 score: 4.5 bits; conditional E-value: 0.016
EEEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTTSSEEEEES-CCCHHHHCS-TTS CS
Methyltransf_4 4 vvleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkiealelkNlrilrgdalkvllelledgs 72
+le+G G G+f+ +lAk +++ +++ ++ +ak k ++ + Nl l+ d ++l ++ +s
tr|S4RMG0|S4RMG0_PETMA 50 DILELGAGIGRFTGHLAKIANHVT--AVDFMENFIAKN--KEDNGHRGNLTFLQADV-TQL--DFPANS 111
589***************987665..677777777663..44444556777777774.444..455555 PP
== domain 2 score: 8.7 bits; conditional E-value: 0.00082
EEEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTTSSEEEEES-CCCHHHHCS-TTSE CS
Methyltransf_4 4 vvleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkiealelkNlrilrgdalkvllelledgsl 73
vl++GcG G+ ++k +++lG+++++++va +++++ ++++ ++ +da+k ++++++s+
tr|S4RMG0|S4RMG0_PETMA 284 KVLDVGCGIGGGDFLMSKLY-GVEVLGVDLSSNMVAIAMERAVEEDAPLVQFEISDATK---RVFPENSF 349
689********999999998.589******************99998888887788744...34666655 PP
>> tr|S4RFT9|S4RFT9_PETMA Zgc:162396 OS=Petromyzon marinus OX=7757 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 11.0 0.0 0.00015 0.16 4 60 .. 44 95 .. 42 104 .. 0.82
2 ? 2.2 0.0 0.081 85 97 115 .. 120 138 .. 117 172 .. 0.90
Alignments for each domain:
== domain 1 score: 11.0 bits; conditional E-value: 0.00015
EEEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTTSSEEEEES-C CS
Methyltransf_4 4 vvleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkiealelkNlrilrgda 60
+ +++GcG+G+ + l+ P ++G+++++ +++++ + ++ +N++++ g a
tr|S4RFT9|S4RFT9_PETMA 44 LAVDVGCGSGQCTRLLSRCCPR--VVGVDVSEAMIREATRV---NRTENIAYTVGTA 95
679****************996..69********9998653...4566777777766 PP
== domain 2 score: 2.2 bits; conditional E-value: 0.081
HHHHHHHHHHEEEEEEEEE CS
Methyltransf_4 97 pellkelarvLkkgGvlel 115
p ++ e+arvL++gG l +
tr|S4RFT9|S4RFT9_PETMA 120 PDFVREAARVLQPGGCLAV 138
689************9976 PP
>> tr|S4RRK5|S4RRK5_PETMA Methyltransferase-like protein OS=Petromyzon marinus OX=7757 PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? -2.9 0.5 2.9 3e+03 154 168 .. 57 71 .. 41 92 .. 0.50
2 ? 11.5 0.0 0.00011 0.11 5 46 .. 185 227 .. 181 262 .. 0.77
3 ? -2.6 0.0 2.4 2.5e+03 98 115 .. 274 291 .. 272 297 .. 0.83
Alignments for each domain:
== domain 1 score: -2.9 bits; conditional E-value: 2.9
CCSSTTCCCCCCTTS CS
Methyltransf_4 154 riatkyeqkvqskgk 168
+ +t+ e+ +++k +
tr|S4RRK5|S4RRK5_PETMA 57 QWTTEQEEEARHKVQ 71
333333333333222 PP
== domain 2 score: 11.5 bits; conditional E-value: 0.00011
EEEET-TTSHHH..HHHHHHSTTSEEEEEES-HHHHHHHHHHHH CS
Methyltransf_4 5 vleiGcGkGefl..valAkknPdknflGiEirvkvvakvlkkie 46
+leiGcG G+ + + + +++Pd+ + G + +++ v+ v ++ +
tr|S4RRK5|S4RRK5_PETMA 185 ILEIGCGAGNTIfpILQTNNDPDVFVYGCDFSQSAVELVKSH-Q 227
79*******965227789999**********99999765444.3 PP
== domain 3 score: -2.6 bits; conditional E-value: 2.4
HHHHHHHHHEEEEEEEEE CS
Methyltransf_4 98 ellkelarvLkkgGvlel 115
+ ++ l r Lk+gGv+ +
tr|S4RRK5|S4RRK5_PETMA 274 AAVTRLSRLLKPGGVFLF 291
568889999*****9876 PP
>> tr|S4RQZ8|S4RQZ8_PETMA THUMP domain containing 2 OS=Petromyzon marinus OX=7757 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 7.0 0.0 0.0027 2.8 4 46 .. 270 312 .. 267 327 .. 0.89
2 ? 3.7 0.1 0.028 29 96 115 .. 360 379 .. 354 381 .. 0.89
Alignments for each domain:
== domain 1 score: 7.0 bits; conditional E-value: 0.0027
EEEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHH CS
Methyltransf_4 4 vvleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkie 46
vv++ cG+G++l++ A + ++ +lG ++ + +a++ ++i+
tr|S4RQZ8|S4RQZ8_PETMA 270 VVMDPMCGMGTLLLEAAMAWKTVRCLGTDVDAQQLAHAKENIH 312
566777***************************9999998886 PP
== domain 2 score: 3.7 bits; conditional E-value: 0.028
SHHHHHHHHHHEEEEEEEEE CS
Methyltransf_4 96 qpellkelarvLkkgGvlel 115
p++l+e++rvL++gG+++l
tr|S4RQZ8|S4RQZ8_PETMA 360 MPKILQEMMRVLRVGGNIVL 379
6899*************976 PP
>> tr|S4R827|S4R827_PETMA Protein-L-isoaspartate (D-aspartate) O-methyltransferase OS=Petromyzon marinus OX=7757 PE=4 S
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 11.4 0.0 0.00012 0.12 4 50 .. 83 130 .. 80 139 .. 0.88
Alignments for each domain:
== domain 1 score: 11.4 bits; conditional E-value: 0.00012
EEEEET-TTSHHHHHHHHHST.TSEEEEEES-HHHHHHHHHHHHHCTT CS
Methyltransf_4 4 vvleiGcGkGeflvalAkknP.dknflGiEirvkvvakvlkkiealel 50
vl++G+G+G ++ +A + + +++Gi+ +++v++++k+++++++
tr|S4R827|S4R827_PETMA 83 SVLDVGSGSGYLTACIARMVGsSGKVFGIDHIQELVDEAIKNVNKDDM 130
689**************99751679******************99876 PP
>> tr|S4RFJ6|S4RFJ6_PETMA Uncharacterized protein OS=Petromyzon marinus OX=7757 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 11.6 0.0 0.0001 0.11 100 165 .. 54 119 .. 40 125 .. 0.94
Alignments for each domain:
== domain 1 score: 11.6 bits; conditional E-value: 0.0001
HHHHHHHEEEEEEEEEEESHHHHHHHHHHHHHCSTTEEESSCCCSCCTCHCHHCCCSSTTCCCCCC CS
Methyltransf_4 100 lkelarvLkkgGvlelaTDveeyaeemlkvleeeplferlskeeeleeeplsvlriatkyeqkvqs 165
l++++ +L + G++ l D++ + e+ + l + ++f + ++ + ee s+lr+a ++ +kvq
tr|S4RFJ6|S4RFJ6_PETMA 54 LQDAQVKLFVTGLFSLNHDIPAFKEHLRDFLVQIKEFAGEDTSDLYLEERESSLRQANEEKRKVQM 119
7889999*******************************************************9985 PP
>> tr|S4RXY4|S4RXY4_PETMA Methyltransferase-like protein OS=Petromyzon marinus OX=7757 PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 10.7 0.0 0.0002 0.21 2 80 .. 93 171 .. 92 172 .. 0.89
Alignments for each domain:
== domain 1 score: 10.7 bits; conditional E-value: 0.0002
-EEEEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTTSSEEEEES-CCCHHHHCS-TTSEEEEEEES CS
Methyltransf_4 2 apvvleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkiealelkNlrilrgdalkvllelledgslekifilF 80
+ vvle GcG G+ l l +++P++ + + + + + v+ v ++ ++ + l+ + ++ l e +++g+++ + + F
tr|S4RXY4|S4RXY4_PETMA 93 RLVVLEAGCGVGNCLFPLLEEDPNIFVYACDFSPRAVDFVKSNPLYSKERCLAFQCDLTQNSLVENVPEGTVDAVTLIF 171
6799*********************************999998888888888888888888888888888888888877 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (173 nodes)
Target sequences: 13539 (5048892 residues searched)
Passed MSV filter: 323 (0.023857); expected 270.8 (0.02)
Passed bias filter: 249 (0.0183913); expected 270.8 (0.02)
Passed Vit filter: 44 (0.00324987); expected 13.5 (0.001)
Passed Fwd filter: 13 (0.000960189); expected 0.1 (1e-05)
Initial search space (Z): 13539 [actual number of targets]
Domain search space (domZ): 13 [number of targets reported over threshold]
# CPU time: 0.09u 0.00s 00:00:00.09 Elapsed: 00:00:00.04
# Mc/sec: 21836.46
//
[ok]