# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/Methyltransf_4.hmm.txt
# target sequence database:        proteomes/Pseudomonas_aeruginosa.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       Methyltransf_4  [M=173]
Accession:   PF02390.16
Description: Putative methyltransferase
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
    1.4e-55  185.8   0.0    1.7e-55  185.5   0.0    1.1  1  sp|Q9I6B3|TRMB_PSEAE    tRNA (guanine-N(7)-)-methyltransferas
    5.2e-08   30.9   0.0    1.1e-07   29.9   0.0    1.4  1  tr|Q9I4P1|Q9I4P1_PSEAE  Uncharacterized protein OS=Pseudomona
    6.6e-05   20.8   0.0    0.00013   19.9   0.0    1.5  1  tr|Q9HY94|Q9HY94_PSEAE  Uncharacterized protein OS=Pseudomona
    0.00011   20.0   0.0    0.00016   19.5   0.0    1.2  1  sp|Q9HVC8|PRMC_PSEAE    Release factor glutamine methyltransf
    0.00019   19.3   0.0    0.00029   18.7   0.0    1.3  1  sp|Q9HV78|TRMA_PSEAE    tRNA/tmRNA (uracil-C(5))-methyltransf
    0.00063   17.6   0.0     0.0014   16.4   0.0    1.5  2  tr|Q9I1T6|Q9I1T6_PSEAE  Uncharacterized protein OS=Pseudomona
     0.0029   15.4   0.0     0.0052   14.6   0.0    1.3  1  sp|Q9HZU0|COBL_PSEAE    Precorrin-6Y C(5,15)-methyltransferas
     0.0042   14.9   0.0     0.0067   14.3   0.0    1.3  1  tr|Q9I281|Q9I281_PSEAE  Uncharacterized protein OS=Pseudomona
  ------ inclusion threshold ------
      0.057   11.2   0.0       0.13   10.1   0.0    1.6  1  tr|Q9I5Y9|Q9I5Y9_PSEAE  Probable transcriptional regulator OS


Domain annotation for each sequence (and alignments):
>> sp|Q9I6B3|TRMB_PSEAE  tRNA (guanine-N(7)-)-methyltransferase OS=Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  185.5   0.0   2.7e-58   1.7e-55       2     173 .]      69     238 ..      68     238 .. 0.98

  Alignments for each domain:
  == domain 1  score: 185.5 bits;  conditional E-value: 2.7e-58
                           -EEEEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTTSSEEEEES-CCCHHHHCS-TTSEEEEEEES-----SGGGG CS
        Methyltransf_4   2 apvvleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkiealelkNlrilrgdalkvllelledgslekifilFPDPwfKkrhh 90 
                           ap + eiG+G+G++++++A + Pd++f+G+E+++++v ++l+    ++l N+r+   dal+vl++ ++d+sl+++ ++FPDPw+Kkrhh
  sp|Q9I6B3|TRMB_PSEAE  69 APRTFEIGFGMGHSTLEMAAAAPDIDFIGVEVHKPGVGALLNGLLTQGLGNVRVYSCDALEVLRHCVADASLDRLLLFFPDPWHKKRHH 157
                           68899************************************************************************************ PP

                           GGSTTSHHHHHHHHHHEEEEEEEEEEESHHHHHHHHHHHHHCSTTEEESSCCCSCCTCHCHHCCCSSTTCCCCCCTTSS-EEE CS
        Methyltransf_4  91 KrRllqpellkelarvLkkgGvlelaTDveeyaeemlkvleeeplferlskeeeleeeplsvlriatkyeqkvqskgkeiyel 173
                           KrR++qpe+ + + r+Lk+gGvl++aTD+e+yae+ml+v+++ p + +  ++    ++p+   r++tk+e++ +++g+ +++l
  sp|Q9I6B3|TRMB_PSEAE 158 KRRIVQPEFAELVRRKLKVGGVLHMATDWEPYAEHMLDVMSAAPGYRNQAEDGRFVPRPQ--ERPVTKFERRGERLGHGVWDL 238
                           *********************************************************999..9*****************985 PP

>> tr|Q9I4P1|Q9I4P1_PSEAE  Uncharacterized protein OS=Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.9   0.0   1.7e-10   1.1e-07       5      62 ..      71     128 ..      68     135 .. 0.91

  Alignments for each domain:
  == domain 1  score: 29.9 bits;  conditional E-value: 1.7e-10
                             EEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTTSSEEEEES-CCC CS
          Methyltransf_4   5 vleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkiealelkNlrilrgdalk 62 
                             vl+iGcG G++   lA++ P+ ++lGi+ +  +v+k+ +++++++++ l+  r  a++
  tr|Q9I4P1|Q9I4P1_PSEAE  71 VLDIGCGIGRWGWLLAEEAPQADYLGIDFSAALVEKACDEARQRGYERLLFQRMSATD 128
                             89*******************************************9999888877755 PP

>> tr|Q9HY94|Q9HY94_PSEAE  Uncharacterized protein OS=Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.9   0.0     2e-07   0.00013       5      49 ..     180     224 ..     176     251 .. 0.90

  Alignments for each domain:
  == domain 1  score: 19.9 bits;  conditional E-value: 2e-07
                             EEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCT CS
          Methyltransf_4   5 vleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkieale 49 
                             vl+ GcG+G + + +Ak++P+ ++ G + + ++++++ +++ea +
  tr|Q9HY94|Q9HY94_PSEAE 180 VLDFGCGSGLAAIMMAKAFPEAQVYGCDFHAPSIERARANAEAAG 224
                             89**********************************999988874 PP

>> sp|Q9HVC8|PRMC_PSEAE  Release factor glutamine methyltransferase OS=Pseudomonas aeruginosa (strain ATCC 15692 / DSM 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.5   0.0   2.6e-07   0.00016       3      58 ..     110     165 ..     108     173 .. 0.92

  Alignments for each domain:
  == domain 1  score: 19.5 bits;  conditional E-value: 2.6e-07
                           EEEEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTTSSEEEEES CS
        Methyltransf_4   3 pvvleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkiealelkNlrilrg 58 
                            +vl++G+G G + +alA ++P +++ +++  ++ va + ++ ++l l+N+++ r+
  sp|Q9HVC8|PRMC_PSEAE 110 ATVLDLGTGTGAIALALASERPLWTVTAVDRVEEAVALAERNRQRLLLENVEVRRS 165
                           689************************************************98765 PP

>> sp|Q9HV78|TRMA_PSEAE  tRNA/tmRNA (uracil-C(5))-methyltransferase OS=Pseudomonas aeruginosa (strain ATCC 15692 / DSM 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.7   0.0   4.7e-07   0.00029       5      69 ..     211     272 ..     207     283 .. 0.89

  Alignments for each domain:
  == domain 1  score: 18.7 bits;  conditional E-value: 4.7e-07
                           EEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTTSSEEEEES-CCCHHHHCS- CS
        Methyltransf_4   5 vleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkiealelkNlrilrgdalkvllelle 69 
                           +le+ cG+G+f++ lA++    ++l+ Ei++++v+++l++ +++ + N+ ++r  a + l+++l+
  sp|Q9HV78|TRMA_PSEAE 211 LLELYCGNGNFTLPLATRV--RKVLATEISKSSVNAALANLADNAVDNVSLVRLSA-EELTQALN 272
                           68999***********997..6789******************************9.66666654 PP

>> tr|Q9I1T6|Q9I1T6_PSEAE  Uncharacterized protein OS=Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.4   0.0   2.3e-06    0.0014       6      60 ..     141     195 ..     138     204 .. 0.93
   2 ?   -3.1   0.0       2.4   1.5e+03     100     118 ..     237     255 ..     234     259 .. 0.81

  Alignments for each domain:
  == domain 1  score: 16.4 bits;  conditional E-value: 2.3e-06
                             EEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTTSSEEEEES-C CS
          Methyltransf_4   6 leiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkiealelkNlrilrgda 60 
                             ++iGcG G   +++A + Pd ++ G++i+   ++ +  +++  ++ Nl + r+d 
  tr|Q9I1T6|Q9I1T6_PSEAE 141 ADIGCGAGPGAIRIAMACPDAEVHGLDINPAALDLARVNAALAGVGNLTLARSDL 195
                             8*********************************999999999******999986 PP

  == domain 2  score: -3.1 bits;  conditional E-value: 2.4
                             HHHHHHHEEEEEEEEEEES CS
          Methyltransf_4 100 lkelarvLkkgGvlelaTD 118
                             ++++ ++L+ gG+l l T 
  tr|Q9I1T6|Q9I1T6_PSEAE 237 VDAALERLEAGGSLLLYTG 255
                             67788999****9999885 PP

>> sp|Q9HZU0|COBL_PSEAE  Precorrin-6Y C(5,15)-methyltransferase [decarboxylating] OS=Pseudomonas aeruginosa (strain ATCC
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.6   0.0   8.5e-06    0.0052       5      69 ..     258     322 ..     255     327 .. 0.92

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 8.5e-06
                           EEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTTSSEEEEES-CCCHHHHCS- CS
        Methyltransf_4   5 vleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkiealelkNlrilrgdalkvllelle 69 
                           + ++G G G++ ++   ++P++  ++iE + ++ +++ ++ +al++  l+++ g a + llel e
  sp|Q9HZU0|COBL_PSEAE 258 LWDVGAGCGSIGIEWMRAHPSCRAIAIEANDERQEHIRHNRDALGVPTLHLVAGSAPEALLELPE 322
                           679*****************************************************999987655 PP

>> tr|Q9I281|Q9I281_PSEAE  Uncharacterized protein OS=Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.3   0.0   1.1e-05    0.0067       5      59 ..      44      99 ..      40     106 .. 0.87

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 1.1e-05
                            EEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHC.TTSSEEEEES- CS
          Methyltransf_4  5 vleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkieal.elkNlrilrgd 59
                            +l +GcG G+ l +lA  +P + f++ +++ +++a + ++ ++l  l+ +++++gd
  tr|Q9I281|Q9I281_PSEAE 44 LLSVGCGAGGELAELAGLRPGWRFVAADLSADMLALARQRCARLgLLERIELHCGD 99
                            688**********************************9999999445677777777 PP

>> tr|Q9I5Y9|Q9I5Y9_PSEAE  Probable transcriptional regulator OS=Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 /
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   0.0   0.00021      0.13       4      70 ..     168     229 ..     166     272 .. 0.79

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 0.00021
                             EEEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTTSSEEEEES-CCCHHHHCS-T CS
          Methyltransf_4   4 vvleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkiealelkNlrilrgdalkvllelled 70 
                             + le+G G G+fl +lA ++ +++  +++ +  +++ + ++ ++++l N+r+   dal+   ++ e+
  tr|Q9I5Y9|Q9I5Y9_PSEAE 168 TALEVGPGDGGFLPELARRFRQVT--ALDNSAAMLELARQRCKEEGLGNVRLELADALQ---DAAEP 229
                             579****************97765..789***************************954...44433 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (173 nodes)
Target sequences:                         5563  (1857172 residues searched)
Passed MSV filter:                       108  (0.019414); expected 111.3 (0.02)
Passed bias filter:                      108  (0.019414); expected 111.3 (0.02)
Passed Vit filter:                        22  (0.0039547); expected 5.6 (0.001)
Passed Fwd filter:                         9  (0.00161783); expected 0.1 (1e-05)
Initial search space (Z):               5563  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.04u 0.00s 00:00:00.04 Elapsed: 00:00:00.02
# Mc/sec: 16064.54
//
[ok]