# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/Methyltransf_4.hmm.txt # target sequence database: proteomes/Pseudomonas_aeruginosa.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: Methyltransf_4 [M=173] Accession: PF02390.16 Description: Putative methyltransferase Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.4e-55 185.8 0.0 1.7e-55 185.5 0.0 1.1 1 sp|Q9I6B3|TRMB_PSEAE tRNA (guanine-N(7)-)-methyltransferas 5.2e-08 30.9 0.0 1.1e-07 29.9 0.0 1.4 1 tr|Q9I4P1|Q9I4P1_PSEAE Uncharacterized protein OS=Pseudomona 6.6e-05 20.8 0.0 0.00013 19.9 0.0 1.5 1 tr|Q9HY94|Q9HY94_PSEAE Uncharacterized protein OS=Pseudomona 0.00011 20.0 0.0 0.00016 19.5 0.0 1.2 1 sp|Q9HVC8|PRMC_PSEAE Release factor glutamine methyltransf 0.00019 19.3 0.0 0.00029 18.7 0.0 1.3 1 sp|Q9HV78|TRMA_PSEAE tRNA/tmRNA (uracil-C(5))-methyltransf 0.00063 17.6 0.0 0.0014 16.4 0.0 1.5 2 tr|Q9I1T6|Q9I1T6_PSEAE Uncharacterized protein OS=Pseudomona 0.0029 15.4 0.0 0.0052 14.6 0.0 1.3 1 sp|Q9HZU0|COBL_PSEAE Precorrin-6Y C(5,15)-methyltransferas 0.0042 14.9 0.0 0.0067 14.3 0.0 1.3 1 tr|Q9I281|Q9I281_PSEAE Uncharacterized protein OS=Pseudomona ------ inclusion threshold ------ 0.057 11.2 0.0 0.13 10.1 0.0 1.6 1 tr|Q9I5Y9|Q9I5Y9_PSEAE Probable transcriptional regulator OS Domain annotation for each sequence (and alignments): >> sp|Q9I6B3|TRMB_PSEAE tRNA (guanine-N(7)-)-methyltransferase OS=Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 185.5 0.0 2.7e-58 1.7e-55 2 173 .] 69 238 .. 68 238 .. 0.98 Alignments for each domain: == domain 1 score: 185.5 bits; conditional E-value: 2.7e-58 -EEEEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTTSSEEEEES-CCCHHHHCS-TTSEEEEEEES-----SGGGG CS Methyltransf_4 2 apvvleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkiealelkNlrilrgdalkvllelledgslekifilFPDPwfKkrhh 90 ap + eiG+G+G++++++A + Pd++f+G+E+++++v ++l+ ++l N+r+ dal+vl++ ++d+sl+++ ++FPDPw+Kkrhh sp|Q9I6B3|TRMB_PSEAE 69 APRTFEIGFGMGHSTLEMAAAAPDIDFIGVEVHKPGVGALLNGLLTQGLGNVRVYSCDALEVLRHCVADASLDRLLLFFPDPWHKKRHH 157 68899************************************************************************************ PP GGSTTSHHHHHHHHHHEEEEEEEEEEESHHHHHHHHHHHHHCSTTEEESSCCCSCCTCHCHHCCCSSTTCCCCCCTTSS-EEE CS Methyltransf_4 91 KrRllqpellkelarvLkkgGvlelaTDveeyaeemlkvleeeplferlskeeeleeeplsvlriatkyeqkvqskgkeiyel 173 KrR++qpe+ + + r+Lk+gGvl++aTD+e+yae+ml+v+++ p + + ++ ++p+ r++tk+e++ +++g+ +++l sp|Q9I6B3|TRMB_PSEAE 158 KRRIVQPEFAELVRRKLKVGGVLHMATDWEPYAEHMLDVMSAAPGYRNQAEDGRFVPRPQ--ERPVTKFERRGERLGHGVWDL 238 *********************************************************999..9*****************985 PP >> tr|Q9I4P1|Q9I4P1_PSEAE Uncharacterized protein OS=Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.9 0.0 1.7e-10 1.1e-07 5 62 .. 71 128 .. 68 135 .. 0.91 Alignments for each domain: == domain 1 score: 29.9 bits; conditional E-value: 1.7e-10 EEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTTSSEEEEES-CCC CS Methyltransf_4 5 vleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkiealelkNlrilrgdalk 62 vl+iGcG G++ lA++ P+ ++lGi+ + +v+k+ +++++++++ l+ r a++ tr|Q9I4P1|Q9I4P1_PSEAE 71 VLDIGCGIGRWGWLLAEEAPQADYLGIDFSAALVEKACDEARQRGYERLLFQRMSATD 128 89*******************************************9999888877755 PP >> tr|Q9HY94|Q9HY94_PSEAE Uncharacterized protein OS=Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.9 0.0 2e-07 0.00013 5 49 .. 180 224 .. 176 251 .. 0.90 Alignments for each domain: == domain 1 score: 19.9 bits; conditional E-value: 2e-07 EEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCT CS Methyltransf_4 5 vleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkieale 49 vl+ GcG+G + + +Ak++P+ ++ G + + ++++++ +++ea + tr|Q9HY94|Q9HY94_PSEAE 180 VLDFGCGSGLAAIMMAKAFPEAQVYGCDFHAPSIERARANAEAAG 224 89**********************************999988874 PP >> sp|Q9HVC8|PRMC_PSEAE Release factor glutamine methyltransferase OS=Pseudomonas aeruginosa (strain ATCC 15692 / DSM 2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.5 0.0 2.6e-07 0.00016 3 58 .. 110 165 .. 108 173 .. 0.92 Alignments for each domain: == domain 1 score: 19.5 bits; conditional E-value: 2.6e-07 EEEEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTTSSEEEEES CS Methyltransf_4 3 pvvleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkiealelkNlrilrg 58 +vl++G+G G + +alA ++P +++ +++ ++ va + ++ ++l l+N+++ r+ sp|Q9HVC8|PRMC_PSEAE 110 ATVLDLGTGTGAIALALASERPLWTVTAVDRVEEAVALAERNRQRLLLENVEVRRS 165 689************************************************98765 PP >> sp|Q9HV78|TRMA_PSEAE tRNA/tmRNA (uracil-C(5))-methyltransferase OS=Pseudomonas aeruginosa (strain ATCC 15692 / DSM 2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.7 0.0 4.7e-07 0.00029 5 69 .. 211 272 .. 207 283 .. 0.89 Alignments for each domain: == domain 1 score: 18.7 bits; conditional E-value: 4.7e-07 EEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTTSSEEEEES-CCCHHHHCS- CS Methyltransf_4 5 vleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkiealelkNlrilrgdalkvllelle 69 +le+ cG+G+f++ lA++ ++l+ Ei++++v+++l++ +++ + N+ ++r a + l+++l+ sp|Q9HV78|TRMA_PSEAE 211 LLELYCGNGNFTLPLATRV--RKVLATEISKSSVNAALANLADNAVDNVSLVRLSA-EELTQALN 272 68999***********997..6789******************************9.66666654 PP >> tr|Q9I1T6|Q9I1T6_PSEAE Uncharacterized protein OS=Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.4 0.0 2.3e-06 0.0014 6 60 .. 141 195 .. 138 204 .. 0.93 2 ? -3.1 0.0 2.4 1.5e+03 100 118 .. 237 255 .. 234 259 .. 0.81 Alignments for each domain: == domain 1 score: 16.4 bits; conditional E-value: 2.3e-06 EEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTTSSEEEEES-C CS Methyltransf_4 6 leiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkiealelkNlrilrgda 60 ++iGcG G +++A + Pd ++ G++i+ ++ + +++ ++ Nl + r+d tr|Q9I1T6|Q9I1T6_PSEAE 141 ADIGCGAGPGAIRIAMACPDAEVHGLDINPAALDLARVNAALAGVGNLTLARSDL 195 8*********************************999999999******999986 PP == domain 2 score: -3.1 bits; conditional E-value: 2.4 HHHHHHHEEEEEEEEEEES CS Methyltransf_4 100 lkelarvLkkgGvlelaTD 118 ++++ ++L+ gG+l l T tr|Q9I1T6|Q9I1T6_PSEAE 237 VDAALERLEAGGSLLLYTG 255 67788999****9999885 PP >> sp|Q9HZU0|COBL_PSEAE Precorrin-6Y C(5,15)-methyltransferase [decarboxylating] OS=Pseudomonas aeruginosa (strain ATCC # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.6 0.0 8.5e-06 0.0052 5 69 .. 258 322 .. 255 327 .. 0.92 Alignments for each domain: == domain 1 score: 14.6 bits; conditional E-value: 8.5e-06 EEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTTSSEEEEES-CCCHHHHCS- CS Methyltransf_4 5 vleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkiealelkNlrilrgdalkvllelle 69 + ++G G G++ ++ ++P++ ++iE + ++ +++ ++ +al++ l+++ g a + llel e sp|Q9HZU0|COBL_PSEAE 258 LWDVGAGCGSIGIEWMRAHPSCRAIAIEANDERQEHIRHNRDALGVPTLHLVAGSAPEALLELPE 322 679*****************************************************999987655 PP >> tr|Q9I281|Q9I281_PSEAE Uncharacterized protein OS=Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.3 0.0 1.1e-05 0.0067 5 59 .. 44 99 .. 40 106 .. 0.87 Alignments for each domain: == domain 1 score: 14.3 bits; conditional E-value: 1.1e-05 EEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHC.TTSSEEEEES- CS Methyltransf_4 5 vleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkieal.elkNlrilrgd 59 +l +GcG G+ l +lA +P + f++ +++ +++a + ++ ++l l+ +++++gd tr|Q9I281|Q9I281_PSEAE 44 LLSVGCGAGGELAELAGLRPGWRFVAADLSADMLALARQRCARLgLLERIELHCGD 99 688**********************************9999999445677777777 PP >> tr|Q9I5Y9|Q9I5Y9_PSEAE Probable transcriptional regulator OS=Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.1 0.0 0.00021 0.13 4 70 .. 168 229 .. 166 272 .. 0.79 Alignments for each domain: == domain 1 score: 10.1 bits; conditional E-value: 0.00021 EEEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTTSSEEEEES-CCCHHHHCS-T CS Methyltransf_4 4 vvleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkiealelkNlrilrgdalkvllelled 70 + le+G G G+fl +lA ++ +++ +++ + +++ + ++ ++++l N+r+ dal+ ++ e+ tr|Q9I5Y9|Q9I5Y9_PSEAE 168 TALEVGPGDGGFLPELARRFRQVT--ALDNSAAMLELARQRCKEEGLGNVRLELADALQ---DAAEP 229 579****************97765..789***************************954...44433 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (173 nodes) Target sequences: 5563 (1857172 residues searched) Passed MSV filter: 108 (0.019414); expected 111.3 (0.02) Passed bias filter: 108 (0.019414); expected 111.3 (0.02) Passed Vit filter: 22 (0.0039547); expected 5.6 (0.001) Passed Fwd filter: 9 (0.00161783); expected 0.1 (1e-05) Initial search space (Z): 5563 [actual number of targets] Domain search space (domZ): 9 [number of targets reported over threshold] # CPU time: 0.04u 0.00s 00:00:00.04 Elapsed: 00:00:00.02 # Mc/sec: 16064.54 // [ok]