# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/Methyltransf_4.hmm.txt
# target sequence database: proteomes/Saccharomyces_cerevisiae.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: Methyltransf_4 [M=173]
Accession: PF02390.16
Description: Putative methyltransferase
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
2.1e-63 211.3 0.1 3e-63 210.8 0.1 1.2 1 sp|Q12009|TRMB_YEAST tRNA (guanine-N(7)-)-methyltransferase
0.00014 19.9 0.0 0.00021 19.3 0.0 1.3 1 sp|P32643|TMT1_YEAST Trans-aconitate 3-methyltransferase OS=
0.00068 17.6 0.0 0.0013 16.7 0.0 1.4 1 sp|P40516|EFM4_YEAST Protein-lysine N-methyltransferase EFM4
0.0051 14.8 0.0 0.013 13.4 0.0 1.7 1 sp|P33753|TRM2_YEAST tRNA (uracil(54)-C(5))-methyltransferas
------ inclusion threshold ------
0.026 12.5 0.0 0.057 11.3 0.0 1.5 1 sp|P32783|MCES_YEAST mRNA cap guanine-N7 methyltransferase O
Domain annotation for each sequence (and alignments):
>> sp|Q12009|TRMB_YEAST tRNA (guanine-N(7)-)-methyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 210.8 0.1 2.5e-66 3e-63 2 172 .. 96 274 .. 95 275 .. 0.98
Alignments for each domain:
== domain 1 score: 210.8 bits; conditional E-value: 2.5e-66
-EEEEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHC........TTSSEEEEES-CCCHHHHCS-TTSEEEEEEES-- CS
Methyltransf_4 2 apvvleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkieal........elkNlrilrgdalkvllelledgslekifilFPD 82
++++++iGcG G+++++l++++P+ ++lG+Eirv+v+++v ++i al +++N+++lrg+a+k+l++++e+g+l+k+f++FPD
sp|Q12009|TRMB_YEAST 96 KVTIADIGCGFGGLMIDLSPAFPEDLILGMEIRVQVTNYVEDRIIALrnntaskhGFQNINVLRGNAMKFLPNFFEKGQLSKMFFCFPD 184
6899*****************************************9999**************************************** PP
---SGGGGGGSTTSHHHHHHHHHHEEEEEEEEEEESHHHHHHHHHHHHHCSTTEEESSCCCSCCTCHCHHCCCSSTTCCCCCCTTSS-E CS
Methyltransf_4 83 PwfKkrhhKrRllqpellkelarvLkkgGvlelaTDveeyaeemlkvleeeplferlskeeeleeeplsvlriatkyeqkvqskgkeiy 171
P+fK+r+hK R+++++ll+e+a+vLk+gGv++++TDv++++e+m+k+lee+plferlske+e+++e+++++r+at++++kv++k+++++
sp|Q12009|TRMB_YEAST 185 PHFKQRKHKARIITNTLLSEYAYVLKEGGVVYTITDVKDLHEWMVKHLEEHPLFERLSKEWEENDECVKIMRNATEEGKKVERKKGDKF 273
*************************************************************************************9987 PP
E CS
Methyltransf_4 172 e 172
sp|Q12009|TRMB_YEAST 274 V 274
5 PP
>> sp|P32643|TMT1_YEAST Trans-aconitate 3-methyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 19.3 0.0 1.7e-07 0.00021 2 75 .. 37 116 .. 36 133 .. 0.77
Alignments for each domain:
== domain 1 score: 19.3 bits; conditional E-value: 1.7e-07
-EEEEEET-TTSHHHHHHHHH.STTSEEEEEES-HHHHH..HHHHHHHHCTTSSE..EEEES-CCCHH.HHCS-TTSEEE CS
Methyltransf_4 2 apvvleiGcGkGeflvalAkk.nPdknflGiEirvkvva..kvlkkiealelkNl..rilrgdalkvl.lelledgslek 75
+++++++GcG G++++++A++ +P +++G +++ ++++ +v+k+ + +kN+ +i +d +k+l +++ ++++++
sp|P32643|TMT1_YEAST 37 RKLLVDVGCGPGTATLQMAQElKPFEQIIGSDLSATMIKtaEVIKEGSPDTYKNVsfKISSSDDFKFLgADSVDKQKIDM 116
6789***************9768**********99998622567788888999982245666667777334555655555 PP
>> sp|P40516|EFM4_YEAST Protein-lysine N-methyltransferase EFM4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 16.7 0.0 1.1e-06 0.0013 3 56 .. 95 148 .. 93 163 .. 0.91
Alignments for each domain:
== domain 1 score: 16.7 bits; conditional E-value: 1.1e-06
EEEEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTTSSEEEE CS
Methyltransf_4 3 pvvleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkiealelkNlril 56
v+++G+G+G++l +l + + + +++Gi+ ++++v+ + + +ea ++ N+ +
sp|P40516|EFM4_YEAST 95 ASVVDLGTGNGHMLFELHQTEFQGKLVGIDYSEESVKLASNIAEATGVDNFISF 148
679***********************************************8655 PP
>> sp|P33753|TRM2_YEAST tRNA (uracil(54)-C(5))-methyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 13.4 0.0 1.1e-05 0.013 6 68 .. 493 552 .. 488 563 .. 0.79
Alignments for each domain:
== domain 1 score: 13.4 bits; conditional E-value: 1.1e-05
EEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTTSSEEEEES-CCCHHHHCS CS
Methyltransf_4 6 leiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkiealelkNlrilrgdalkvllell 68
++ cG+G f + + +++G+Ei+ ++v + k+++a++++N r + g a + l e++
sp|P33753|TRM2_YEAST 493 VDAYCGSGLFSI--CSSKGVDKVIGVEISADSVSFAEKNAKANGVENCRFIVGKA-EKLFESI 552
566677776554..455566789********************************.6665665 PP
>> sp|P32783|MCES_YEAST mRNA cap guanine-N7 methyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 11.3 0.0 4.7e-05 0.057 4 48 .. 167 210 .. 164 223 .. 0.83
Alignments for each domain:
== domain 1 score: 11.3 bits; conditional E-value: 4.7e-05
EEEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHC CS
Methyltransf_4 4 vvleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkieal 48
vvle+GcGkG+ l + + +f+Gi+i++ +++++ k+ +
sp|P32783|MCES_YEAST 167 VVLELGCGKGGDLRKYGAAG-ISQFIGIDISNASIQEAHKRYRSM 210
89*************99876.5689*************9987653 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (173 nodes)
Target sequences: 6049 (2936363 residues searched)
Passed MSV filter: 255 (0.0421557); expected 121.0 (0.02)
Passed bias filter: 155 (0.0256241); expected 121.0 (0.02)
Passed Vit filter: 22 (0.00363696); expected 6.0 (0.001)
Passed Fwd filter: 5 (0.000826583); expected 0.1 (1e-05)
Initial search space (Z): 6049 [actual number of targets]
Domain search space (domZ): 5 [number of targets reported over threshold]
# CPU time: 0.05u 0.00s 00:00:00.05 Elapsed: 00:00:00.03
# Mc/sec: 16933.03
//
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