# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/Methyltransf_4.hmm.txt
# target sequence database: proteomes/Trichoplax_adhaerens.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: Methyltransf_4 [M=173]
Accession: PF02390.16
Description: Putative methyltransferase
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
2e-49 166.8 0.0 2.4e-49 166.5 0.0 1.1 1 tr|B3RL30|B3RL30_TRIAD tRNA (guanine-N(7)-)-methyltransferas
1.1e-07 30.8 0.1 1.1e-07 30.8 0.1 1.7 2 tr|B3S5B9|B3S5B9_TRIAD Uncharacterized protein OS=Trichoplax
3.5e-05 22.7 0.5 9.9e-05 21.2 0.0 2.0 2 tr|B3RLM9|B3RLM9_TRIAD Uncharacterized protein OS=Trichoplax
0.00024 20.0 0.0 0.00036 19.4 0.0 1.3 1 tr|B3RQF2|B3RQF2_TRIAD Uncharacterized protein OS=Trichoplax
0.0019 17.1 0.1 0.0051 15.7 0.0 1.7 2 tr|B3RUJ8|B3RUJ8_TRIAD Uncharacterized protein OS=Trichoplax
------ inclusion threshold ------
0.01 14.7 0.1 0.044 12.6 0.0 1.9 2 tr|B3RP82|B3RP82_TRIAD Uncharacterized protein OS=Trichoplax
0.026 13.4 0.0 0.042 12.7 0.0 1.3 1 tr|B3RN34|B3RN34_TRIAD Uncharacterized protein OS=Trichoplax
0.03 13.2 0.0 0.052 12.4 0.0 1.4 1 tr|B3S4V8|B3S4V8_TRIAD rRNA adenine N(6)-methyltransferase O
0.043 12.7 0.0 0.068 12.0 0.0 1.3 1 tr|B3S3V1|B3S3V1_TRIAD Uncharacterized protein OS=Trichoplax
0.045 12.6 4.4 1.5 7.7 0.0 2.8 2 tr|B3S2J9|B3S2J9_TRIAD Histone-lysine N-methyltransferase, H
Domain annotation for each sequence (and alignments):
>> tr|B3RL30|B3RL30_TRIAD tRNA (guanine-N(7)-)-methyltransferase OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_18672 P
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 166.5 0.0 2.1e-52 2.4e-49 3 172 .. 47 218 .. 45 219 .. 0.97
Alignments for each domain:
== domain 1 score: 166.5 bits; conditional E-value: 2.1e-52
EEEEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHC......TTSSEEEEES-CCCHHHHCS-TTSEEEEEEES--- CS
Methyltransf_4 3 pvvleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkieal......elkNlrilrgdalkvllelledgslekifilFPDP 83
+ +l+iGcG+G++l++lA+ +Pd+ ++G+Eirvkv+++v ++i+al +++N++i+r++a+k+l++++++g+l+k+f+l+PDP
tr|B3RL30|B3RL30_TRIAD 47 VQFLDIGCGYGGLLITLAPLFPDTYIMGMEIRVKVSDYVKERIAALrinnpgKYNNIAIVRTNAMKYLPNYFKKGQLKKLFFLYPDP 133
579************************************************************************************ PP
--SGGGGGGSTTSHHHHHHHHHHEEEEEEEEEEESHHHHHHHHHHHHHCSTTEEESSCCCSCCTCHCHHCCCSSTTCCCCCCTTSS- CS
Methyltransf_4 84 wfKkrhhKrRllqpellkelarvLkkgGvlelaTDveeyaeemlkvleeeplferlskeeeleeeplsvlriatkyeqkvqskgkei 170
+fKk +hK+R+l + ++++ L+ +G+++++TDvee++ +m ++l+e+plfe ++ e+ ++ +l+ l t+++qkv+++++++
tr|B3RL30|B3RL30_TRIAD 134 HFKKTKHKQRILRH----DIEYLLQLRGLVYTVTDVEEVHIWMKSHLNEHPLFEEVKLESLSHDAILKFLGDCTEEGQKVTRNDGKK 216
***********985....799***************************************************************998 PP
EE CS
Methyltransf_4 171 ye 172
+
tr|B3RL30|B3RL30_TRIAD 217 FT 218
86 PP
>> tr|B3S5B9|B3S5B9_TRIAD Uncharacterized protein OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_59271 PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? -3.7 0.2 3.9 4.5e+03 140 161 .. 22 43 .. 13 46 .. 0.68
2 ! 30.8 0.1 9.6e-11 1.1e-07 3 79 .. 401 475 .. 399 502 .. 0.86
Alignments for each domain:
== domain 1 score: -3.7 bits; conditional E-value: 3.9
SCCCSCCTCHCHHCCCSSTTCC CS
Methyltransf_4 140 skeeeleeeplsvlriatkyeq 161
+++++ +++ ++ ++ tk+e+
tr|B3S5B9|B3S5B9_TRIAD 22 EQNQMHSDQEQHDHYSYTKREE 43
4556666677777888888875 PP
== domain 2 score: 30.8 bits; conditional E-value: 9.6e-11
EEEEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTTSSEEEEES-CCCHHHHCS-TTSEEEEEEE CS
Methyltransf_4 3 pvvleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkiealelkNlrilrgdalkvllelledgslekifil 79
vvl+i+cG G++ + +Ak+ + ++GiE+ ++ ++ + ++e +++kN++ ++g a + l++l+ + s+ +i
tr|B3S5B9|B3S5B9_TRIAD 401 TVVLDICCGTGTIGILMAKNV--NRVIGIEMVEDAIEDARVNAELNDIKNIEFICGKAEDKLPTLVDNLSVISEVIA 475
689***************986..679**************************************9998777555555 PP
>> tr|B3RLM9|B3RLM9_TRIAD Uncharacterized protein OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_19869 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? -1.7 0.2 0.96 1.1e+03 48 67 .. 33 52 .. 9 65 .. 0.50
2 ! 21.2 0.0 8.6e-08 9.9e-05 3 48 .. 95 140 .. 93 148 .. 0.89
Alignments for each domain:
== domain 1 score: -1.7 bits; conditional E-value: 0.96
CTTSSEEEEES-CCCHHHHC CS
Methyltransf_4 48 lelkNlrilrgdalkvllel 67
++l+ l+ +r+d ++++++
tr|B3RLM9|B3RLM9_TRIAD 33 NDLQTLKKIRQDKVELVETT 52
24444555555555555444 PP
== domain 2 score: 21.2 bits; conditional E-value: 8.6e-08
EEEEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHC CS
Methyltransf_4 3 pvvleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkieal 48
+ +l+iGc G++++++Akk+ ++++Gi+i +++ ++ ++i +
tr|B3RLM9|B3RLM9_TRIAD 95 KDCLDIGCNDGHLTIEIAKKFNPNTIVGIDIDASLITRARSNITRI 140
679**********************************999998775 PP
>> tr|B3RQF2|B3RQF2_TRIAD Uncharacterized protein OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_54966 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 19.4 0.0 3.1e-07 0.00036 2 62 .. 50 109 .. 49 126 .. 0.88
Alignments for each domain:
== domain 1 score: 19.4 bits; conditional E-value: 3.1e-07
-EEEEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTTSSEEEEES-CCC CS
Methyltransf_4 2 apvvleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkiealelkNlrilrgdalk 62
++v+++GcG G + v A +++ +++Gi+i + + + ++ie+ el+N+++++ + +
tr|B3RQF2|B3RQF2_TRIAD 50 GKLVCDLGCGCGVLSVGTAMLDAS-LIVGIDIDDDALMIARRNIEEFELENVQLIKANISD 109
5789****************9987.799*****************************9843 PP
>> tr|B3RUJ8|B3RUJ8_TRIAD Uncharacterized protein OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_24037 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 15.7 0.0 4.4e-06 0.0051 3 39 .. 135 171 .. 133 198 .. 0.87
2 ? -2.4 0.0 1.5 1.8e+03 106 137 .. 259 292 .. 250 302 .. 0.69
Alignments for each domain:
== domain 1 score: 15.7 bits; conditional E-value: 4.4e-06
EEEEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHH CS
Methyltransf_4 3 pvvleiGcGkGeflvalAkknPdknflGiEirvkvva 39
++l+i+cG+G + + l +nP+ ++++i++ + +
tr|B3RUJ8|B3RUJ8_TRIAD 135 ITFLDICCGSGAIGLSLLCENPQATCIAIDKDPNAIS 171
579***************************9988775 PP
== domain 2 score: -2.4 bits; conditional E-value: 1.5
HEEEEEEEEEEES..HHHHHHHHHHHHHCSTTEE CS
Methyltransf_4 106 vLkkgGvlelaTD..veeyaeemlkvleeeplfe 137
Lk +G + l D ++e+ e+ l+ + ++
tr|B3RUJ8|B3RUJ8_TRIAD 259 CLKDKGKIWLEVDinHPEMIEHYLNTHDTDFTYD 292
5888999999999666677777666666665555 PP
>> tr|B3RP82|B3RP82_TRIAD Uncharacterized protein OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_53437 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 12.6 0.0 3.8e-05 0.044 5 51 .. 65 109 .. 62 116 .. 0.89
2 ? -1.3 0.0 0.7 8e+02 98 114 .. 148 164 .. 145 173 .. 0.83
Alignments for each domain:
== domain 1 score: 12.6 bits; conditional E-value: 3.8e-05
EEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTTS CS
Methyltransf_4 5 vleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkiealelk 51
+lei cG+G+ l +lA++ + Gi++++ ++a++ k ++++++
tr|B3RP82|B3RP82_TRIAD 65 LLEIACGSGNYLARLATQVD--KAYGIDMNQAMLAQCRTKLDQHQVQ 109
79**************9964..456****************999886 PP
== domain 2 score: -1.3 bits; conditional E-value: 0.7
HHHHHHHHHEEEEEEEE CS
Methyltransf_4 98 ellkelarvLkkgGvle 114
+ e+ rvLk++G++
tr|B3RP82|B3RP82_TRIAD 148 DFFREINRVLKNNGMVI 164
6889999******9986 PP
>> tr|B3RN34|B3RN34_TRIAD Uncharacterized protein OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_63612 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 12.7 0.0 3.6e-05 0.042 4 54 .. 31 81 .. 28 89 .. 0.94
Alignments for each domain:
== domain 1 score: 12.7 bits; conditional E-value: 3.6e-05
EEEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTTSSEE CS
Methyltransf_4 4 vvleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkiealelkNlr 54
v+e+ +G G+++ Ak++ + + Ei+ + ++++ +++++++l+N++
tr|B3RN34|B3RN34_TRIAD 31 SVAEVASGHGQHICFFAKEFRQSVWSPTEINAEYLNRLTENVNREQLSNVK 81
689**********************************************97 PP
>> tr|B3S4V8|B3S4V8_TRIAD rRNA adenine N(6)-methyltransferase OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_29342 PE=3
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 12.4 0.0 4.5e-05 0.052 4 62 .. 26 83 .. 23 91 .. 0.85
Alignments for each domain:
== domain 1 score: 12.4 bits; conditional E-value: 4.5e-05
EEEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHC.TTSSEEEEES-CCC CS
Methyltransf_4 4 vvleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkieal.elkNlrilrgdalk 62
+vleiG G G+++v+l +k k++++ E+ ++ a++ k+++ + + l+i+ gd lk
tr|B3S4V8|B3S4V8_TRIAD 26 TVLEIGPGTGNLTVKLLQKA--KKVIACEVDPRLAAELQKRVQGSpVSTKLHIIVGDVLK 83
79**************8875..789*****************998555678888888765 PP
>> tr|B3S3V1|B3S3V1_TRIAD Uncharacterized protein OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_28751 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 12.0 0.0 5.9e-05 0.068 6 72 .. 98 165 .. 93 178 .. 0.81
Alignments for each domain:
== domain 1 score: 12.0 bits; conditional E-value: 5.9e-05
EEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTTS.SEEEEES-CCCHHHHCS-TTS CS
Methyltransf_4 6 leiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkiealelk.Nlrilrgdalkvllelledgs 72
++iG+G + + lA + +nfl+ E+ ++ v+++ k++ ++l ++i a+++l + l++++
tr|B3S3V1|B3S3V1_TRIAD 98 IDIGTGASCIYPLLAARMNGWNFLATEVDQRCVHYAQKNVTINDLDeKIKIKMVAAQDILCTPLRNEN 165
8*************************************998886641577777777777777666655 PP
>> tr|B3S2J9|B3S2J9_TRIAD Histone-lysine N-methyltransferase, H3 lysine-79 specific OS=Trichoplax adhaerens OX=10228 GN
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 7.7 0.0 0.0013 1.5 4 34 .. 95 125 .. 92 140 .. 0.89
2 ? 2.7 3.3 0.041 48 91 168 .. 339 418 .. 334 423 .. 0.71
Alignments for each domain:
== domain 1 score: 7.7 bits; conditional E-value: 0.0013
EEEEET-TTSHHHHHHHHHSTTSEEEEEES- CS
Methyltransf_4 4 vvleiGcGkGeflvalAkknPdknflGiEir 34
v++++G+G G+++++ A k++ GiE+
tr|B3S2J9|B3S2J9_TRIAD 95 VFIDLGSGVGQAVLQAAASTNCKECWGIEKA 125
89***************************75 PP
== domain 2 score: 2.7 bits; conditional E-value: 0.041
GGSTTSHHHHHHHHHHEEEEEEEEEEES..HHHHHHHHHHHHHCSTTEEESSCCCSCCTC.HCHHCCCSSTTCCCCCCTTS CS
Methyltransf_4 91 KrRllqpellkelarvLkkgGvlelaTD..veeyaeemlkvleeeplferlskeeeleee.plsvlriatkyeqkvqskgk 168
K+R q+ + + +Lk Gv + D +++ e+++k+l++++ ++ +ke++ + + +++ l + e+ ++++++
tr|B3S2J9|B3S2J9_TRIAD 339 KKRKKQHSQFSIMDAKLKA-GVASTDNDseYNNLNEKVIKKLKKHQGIKLKKKEKKIKSNsIKEALTSTADAEELINNQKN 418
6666677777777778875.5666666677899*************99988888776655055555555567776666655 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (173 nodes)
Target sequences: 11518 (5222075 residues searched)
Passed MSV filter: 470 (0.0408057); expected 230.4 (0.02)
Passed bias filter: 299 (0.0259594); expected 230.4 (0.02)
Passed Vit filter: 37 (0.00321236); expected 11.5 (0.001)
Passed Fwd filter: 10 (0.000868206); expected 0.1 (1e-05)
Initial search space (Z): 11518 [actual number of targets]
Domain search space (domZ): 10 [number of targets reported over threshold]
# CPU time: 0.08u 0.00s 00:00:00.08 Elapsed: 00:00:00.03
# Mc/sec: 30113.97
//
[ok]