# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/Methyltransf_5.hmm.txt # target sequence database: proteomes/Nematostella_vectensis.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: Methyltransf_5 [M=309] Accession: PF01795.18 Description: MraW methylase family Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.5e-85 287.2 0.0 3.1e-85 286.8 0.0 1.1 1 tr|A7RIE8|A7RIE8_NEMVE Predicted protein OS=Nematostella vec 1e-31 111.1 0.0 1.3e-31 110.7 0.0 1.1 1 tr|A7TAM4|A7TAM4_NEMVE Predicted protein (Fragment) OS=Nemat ------ inclusion threshold ------ 0.046 13.7 0.0 0.07 13.1 0.0 1.2 1 tr|A7TBN7|A7TBN7_NEMVE Predicted protein (Fragment) OS=Nemat 0.1 12.5 0.9 0.27 11.1 0.2 1.9 2 tr|A7RJC9|A7RJC9_NEMVE Predicted protein OS=Nematostella vec 0.1 12.5 0.0 0.15 12.0 0.0 1.2 1 tr|A7SAF9|A7SAF9_NEMVE Predicted protein OS=Nematostella vec 0.15 11.9 0.2 0.24 11.3 0.2 1.3 1 tr|A7T6Q3|A7T6Q3_NEMVE Predicted protein OS=Nematostella vec Domain annotation for each sequence (and alignments): >> tr|A7RIE8|A7RIE8_NEMVE Predicted protein OS=Nematostella vectensis OX=45351 GN=v1g159091 PE=3 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 286.8 0.0 7.6e-89 3.1e-85 3 308 .. 34 349 .. 32 350 .. 0.91 Alignments for each domain: == domain 1 score: 286.8 bits; conditional E-value: 7.6e-89 XX--TTTHHHHHHT---TT-EEEES--TTSHHHHHHHTT--TTEEEEEES-HHHHHHHTT.......---EEEEES-GGGHHHHHHH CS Methyltransf_5 3 eHvpVLlqevvellepkedgvyiDaTlGaggHsealLeqlselrligidrDksalarakerLk..efekrltlvkgnfkelkealae 87 H+pV+ +e++ +l+pk++ v++DaT+GaggH+ a+L+ + ++ ++drD+ a+++a+ + e++ +l ++g+f+el e l++ tr|A7RIE8|A7RIE8_NEMVE 34 LHIPVMSRECLGFLAPKDGEVFVDATFGAGGHTCAILNSAK-CKVFAVDRDPVAVEIAQVLSTrpEYKGQLIPLQGKFSELFELLSN 119 7************************************9865.5899************9855522566779999************* PP TT..TT-EEEEEEE-S--HHHHH-GGG---SSS--BS---S-TT........SS--HHHHHHH--HHHHHHHHHHHH--TTHHHHHH CS Methyltransf_5 88 an..vtkvdgillDLGvSslqldkaerGFsfaedapLDmRmdqs........aeltAaevlnrlseeeLakilkeygeekfakriak 164 ++ +++dg+llD+G Ss+q+d++ rGFs +d+pLDmRmd++ ++ tAa+v+n++se+eL ++l++yg e+ a ri++ tr|A7RIE8|A7RIE8_NEMVE 120 NGikKESLDGMLLDIGPSSMQFDDPLRGFSLSKDGPLDMRMDSEndtkssrsSSFTAADVVNSISERELISVLRHYGGERDAARISR 206 99555689*********************************975222222214569******************************* PP HHHHHHHHS---BHHHHHHHHHHHS-------.....-TTHHHHHHHHHHHHTHHHHHHHHHHHHHHHEEEEEEEEEEESSHHHHHH CS Methyltransf_5 165 aivekrkkkpiettkelaevikkvvpakekrk...kihpatrvFQAlRIavNdEleeleelleaalellakggrlavisFhSledri 248 a+ ++r ++ i tt++la +++++v + +k k hpat++FQAlRI vNdEl+el+++l+aa +ll +ggrl+visFhS ed i tr|A7RIE8|A7RIE8_NEMVE 207 AVIKARDREHIMTTRQLAAIVANAVGFGRKDKlnrFAHPATKTFQALRILVNDELNELHKALKAAKKLLTPGGRLVVISFHSAEDSI 293 *************************999887766578************************************************** PP HHHHHHHTT-------------------EEEEE.E.E---HHHHHH-GGGTT-EEEEEEE CS Methyltransf_5 249 vkkvfkeaskkeevPaglpvaseelkaklklitkkpilpseeeikeNprsrsakLrviek 308 vk+++k+ +++ ++ + +s++ + + kk++ ps++ei Npr rsakLr++ k tr|A7RIE8|A7RIE8_NEMVE 294 VKHFLKDEATR----KSSKTMSDSDSITWLPLHKKVVSPSDDEIFFNPRCRSAKLRAVVK 349 *******9996....5556667888889999*************************9866 PP >> tr|A7TAM4|A7TAM4_NEMVE Predicted protein (Fragment) OS=Nematostella vectensis OX=45351 GN=v1g152542 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 110.7 0.0 3.2e-35 1.3e-31 24 157 .. 1 145 [. 1 148 [. 0.86 Alignments for each domain: == domain 1 score: 110.7 bits; conditional E-value: 3.2e-35 EEES--TTSHHHHHHHTT--TTEEEEEES-HHHHHHHTT.......---EEEEES-GGGHHHHHHHTT..TT-EEEEEEE-S--HHH CS Methyltransf_5 24 yiDaTlGaggHsealLeqlselrligidrDksalarakerLk..efekrltlvkgnfkelkealaean..vtkvdgillDLGvSslq 106 ++DaT+GaggH+ a+L+ + ++ ++drD+ a+++a+ + e++ +l ++g+f++l e l++++ +++dg+llD+G Ss+q tr|A7TAM4|A7TAM4_NEMVE 1 FVDATFGAGGHTCAILNSAK-CKVFAVDRDPVAVEIAQVLSTrpEYKGQLIPLQGKFSDLFELLSNNGikKESLDGMLLDIGPSSMQ 86 89**************9865.5899************9855522566779999*************99555689************* PP HH-GGG---SSS--BS---S-TT........SS--HHHHHHH--HHHHHHHHHHHH--T CS Methyltransf_5 107 ldkaerGFsfaedapLDmRmdqs........aeltAaevlnrlseeeLakilkeygeek 157 +d++ rGFs +d+pLDmRmd++ ++ tAa+v+n++se+eL ++l++yg e+ tr|A7TAM4|A7TAM4_NEMVE 87 FDDPLRGFSLSKDGPLDMRMDSEndtkssrnSSFTAADVVNSISERELISVLRHYGGER 145 ********************976222222213569*********************998 PP >> tr|A7TBN7|A7TBN7_NEMVE Predicted protein (Fragment) OS=Nematostella vectensis OX=45351 GN=v1g224919 PE=3 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.1 0.0 1.7e-05 0.07 8 78 .. 96 162 .. 93 183 .. 0.83 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 1.7e-05 TTHHHHHHT---TT-EEEES--TTSHHHHHHHTT--TTEEEEEES-HHHHHHHTT.....---EEEEES-G CS Methyltransf_5 8 LlqevvellepkedgvyiDaTlGaggHsealLeqlselrligidrDksalarakerLkefekrltlvkgnf 78 Ll e+v +l p + ++D G+g + al ++ ++ rl+g+dr ++a+a a+++ rl+l ++nf tr|A7TBN7|A7TBN7_NEMVE 96 LLVETVLALLPATSAALLDLGTGTGAIALALASERPAWRLTGVDRVSEAVALAERN----RARLKLSNANF 162 77888889999999*************************************99873....34455555555 PP >> tr|A7RJC9|A7RJC9_NEMVE Predicted protein OS=Nematostella vectensis OX=45351 GN=v1g238725 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.2 0.0 0.38 1.6e+03 216 242 .. 137 163 .. 133 186 .. 0.78 2 ? 11.1 0.2 6.6e-05 0.27 14 100 .. 459 547 .. 444 553 .. 0.83 Alignments for each domain: == domain 1 score: -1.2 bits; conditional E-value: 0.38 HHHHHHHHHHHHHHEEEEEEEEEEESS CS Methyltransf_5 216 leeleelleaalellakggrlavisFh 242 l++++++ +++ ++l+ ggr+ v + tr|A7RJC9|A7RJC9_NEMVE 137 LKKVDKTFAEIQRVLKVGGRFIVCTLA 163 788899999999*********998864 PP == domain 2 score: 11.1 bits; conditional E-value: 6.6e-05 HHT---TT-EEEES--TTSHHHHHHHTT--TTEEEEEES-HHHHHHHTT.....---..EEEEES-GGGHHHHHHHTTTT-EEEEEE CS Methyltransf_5 14 ellepkedgvyiDaTlGaggHsealLeqlselrligidrDksalarakerLkefekr..ltlvkgnfkelkealaeanvtkvdgill 98 +lle+++++ + + lG+gg + + + +s+ ++ +++ D+ ++ +ak+++ e++ vk+ k+++ea + + ++ +i++ tr|A7RJC9|A7RJC9_NEMVE 459 KLLEKEKKKQALIVGLGGGGLAMFIYQFFSQVAIDAVELDEAVVSVAKTQFGCIEDKrlAIHVKDGLKFIEEAHIKVPRPQYHAIMF 545 455555555566688*************************************999887555678888******99999999999999 PP E- CS Methyltransf_5 99 DL 100 D+ tr|A7RJC9|A7RJC9_NEMVE 546 DI 547 96 PP >> tr|A7SAF9|A7SAF9_NEMVE Predicted protein OS=Nematostella vectensis OX=45351 GN=v1g243959 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 0.0 3.6e-05 0.15 23 86 .. 55 118 .. 35 125 .. 0.81 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 3.6e-05 EEEES--TTSHHHHHHHTT--TTEEEEEES-HHHHHHHTT.....-..--EEEEES-GGGHHHHHH CS Methyltransf_5 23 vyiDaTlGaggHsealLeqlselrligidrDksalarakerLkefe..krltlvkgnfkelkeala 86 + +Da G gg + ++ +++ +r+i+id+D+ ++ a+++ + + +r+++v g f+++ +l+ tr|A7SAF9|A7SAF9_NEMVE 55 LIVDAFCGVGGNAIQF--AFTCERVIAIDIDPVKIDCARHNAEIYGvaDRIEFVLGDFRQIVPQLK 118 4689999999987766..78889****************99887755489********99987776 PP >> tr|A7T6Q3|A7T6Q3_NEMVE Predicted protein OS=Nematostella vectensis OX=45351 GN=v1g223098 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.2 6e-05 0.24 14 100 .. 296 384 .. 281 390 .. 0.82 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 6e-05 HHT---TT-EEEES--TTSHHHHHHHTT--TTEEEEEES-HHHHHHHTT.....---..EEEEES-GGGHHHHHHHTTTT-EEEEEE CS Methyltransf_5 14 ellepkedgvyiDaTlGaggHsealLeqlselrligidrDksalarakerLkefekr..ltlvkgnfkelkealaeanvtkvdgill 98 +lle+++++ + + lG+gg + + + +s+ ++ +++ D+ ++ +ak+++ e++ vk+ k+++e + + ++ +i++ tr|A7T6Q3|A7T6Q3_NEMVE 296 KLLEKEKKKQALIVGLGGGGLAMFIYQFFSQVAIDAVELDEAVVSVAKTQFGCIEDKrlAIHVKDGLKFIEESHIKVPRPQYHAIMF 382 455555555566688*************************************99988755567888899999999999999999999 PP E- CS Methyltransf_5 99 DL 100 D+ tr|A7T6Q3|A7T6Q3_NEMVE 383 DI 384 96 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (309 nodes) Target sequences: 24428 (8257945 residues searched) Passed MSV filter: 755 (0.0309072); expected 488.6 (0.02) Passed bias filter: 423 (0.0173162); expected 488.6 (0.02) Passed Vit filter: 36 (0.00147372); expected 24.4 (0.001) Passed Fwd filter: 6 (0.00024562); expected 0.2 (1e-05) Initial search space (Z): 24428 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.19u 0.01s 00:00:00.20 Elapsed: 00:00:00.08 # Mc/sec: 31896.31 // [ok]