# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/Methyltransf_5.hmm.txt # target sequence database: proteomes/Strongylocentrotus_purpuratus.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: Methyltransf_5 [M=309] Accession: PF01795.18 Description: MraW methylase family Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.5e-46 160.0 0.8 1.8e-46 159.7 0.8 1.0 1 tr|W4XVH1|W4XVH1_STRPU Uncharacterized protein OS=Strongyloc 8e-36 124.8 0.0 9.7e-36 124.5 0.0 1.1 1 tr|W4XVH0|W4XVH0_STRPU Uncharacterized protein OS=Strongyloc 0.0008 19.7 0.0 0.78 9.8 0.0 2.2 2 tr|W4ZC76|W4ZC76_STRPU Uncharacterized protein OS=Strongyloc 0.0067 16.6 0.0 7.1 6.7 0.0 3.0 4 tr|W4Y7A2|W4Y7A2_STRPU Uncharacterized protein OS=Strongyloc ------ inclusion threshold ------ 0.23 11.6 0.0 0.44 10.7 0.0 1.4 1 tr|W4XJA0|W4XJA0_STRPU Uncharacterized protein OS=Strongyloc Domain annotation for each sequence (and alignments): >> tr|W4XVH1|W4XVH1_STRPU Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 159.7 0.8 3.1e-50 1.8e-46 131 307 .. 13 201 .. 10 203 .] 0.89 Alignments for each domain: == domain 1 score: 159.7 bits; conditional E-value: 3.1e-50 S--HHHHHHH--HHHHHHHHHHHH--TTHHHHHHHHHHHHHH.S---BHHHHHHHHHHHS-------.........-TTHHHHHHHH CS Methyltransf_5 131 eltAaevlnrlseeeLakilkeygeekfakriakaivekrkk.kpiettkelaevikkvvpakekrk.......kihpatrvFQAlR 209 + tAa+v+n+l++ L++il++ygee ak+ia+ai ++r++ + +++t+ela vi+ + + ++ + h at++FQAlR tr|W4XVH1|W4XVH1_STRPU 13 QPTAADVVNSLDHVTLTQILRTYGEESNAKKIAQAIIDYRTNfNTFSSTSELATVIACCHTHRDAKSnrdklgrHAHTATKTFQALR 99 459***********************************8876489***********99877766655778898899*********** PP HHHHTHHHHHHHHHHHHHHHEEEEEEEEEEESSHHHHHHHHHHHHH..T.T-----.--------------EEEEE.E.E---HHHH CS Methyltransf_5 210 IavNdEleeleelleaalellakggrlavisFhSledrivkkvfke..a.skkeev.Paglpvaseelkaklklitkkpilpseeei 292 I+vN+El+el ++eaa +l+++gg+lav++FhSledr+vk+ ++ ++ +++ +++ +++ +k +++ + + + +eei tr|W4XVH1|W4XVH1_STRPU 100 IFVNNELNELAVAVEAAWDLMRPGGKLAVLTFHSLEDRVVKRSLQGrhVaERGTSLrQKRVESHKDNGAQKWEVVKRNELCADDEEI 186 ******************************************9975113134445567889999999999***************** PP HH-GGGTT-EEEEEE CS Methyltransf_5 293 keNprsrsakLrvie 307 ++Npr+rsakLr + tr|W4XVH1|W4XVH1_STRPU 187 NMNPRARSAKLRTAI 201 ************875 PP >> tr|W4XVH0|W4XVH0_STRPU Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 124.5 0.0 1.7e-39 9.7e-36 2 129 .. 59 186 .. 58 187 .] 0.97 Alignments for each domain: == domain 1 score: 124.5 bits; conditional E-value: 1.7e-39 XXX--TTTHHHHHHT---TT-EEEES--TTSHHHHHHHTT--TTEEEEEES-HHHHHHHTT.....---EEEEES-GGGHHHHHHHT CS Methyltransf_5 2 leHvpVLlqevvellepkedgvyiDaTlGaggHsealLeqlselrligidrDksalarakerLkefekrltlvkgnfkelkealaea 88 + H+pV+++ev+++++p++++vyiD+T+G+ggH++al++ + +++g+drD+ a ++a++ +++ +l + g+f+e+k+ l+++ tr|W4XVH0|W4XVH0_STRPU 59 SLHKPVMVEEVLSFFAPQANQVYIDMTFGGGGHTQALMKCAPGITVYGLDRDPFAHQIAQKLSLHHKGQLCPLLGKFSEVKDLLSQR 145 57***********************************************************88888999****************** PP TTT-EEEEEEE-S--HHHHH-GGG---SSS--BS---S-TT CS Methyltransf_5 89 nvtkvdgillDLGvSslqldkaerGFsfaedapLDmRmdqs 129 +v+ vdgil+D G Ss+q+d++erGF+ +d+pLDmRmd + tr|W4XVH0|W4XVH0_STRPU 146 EVSMVDGILIDAGCSSFQFDSPERGFALSQDGPLDMRMDAN 186 **************************************976 PP >> tr|W4ZC76|W4ZC76_STRPU Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.8 0.0 0.00014 0.78 82 117 .. 47 82 .. 39 98 .. 0.85 2 ! 7.5 0.0 0.00071 4.1 93 116 .. 110 133 .. 94 139 .. 0.89 Alignments for each domain: == domain 1 score: 9.8 bits; conditional E-value: 0.00014 HHHHHHTTTT-EEEEEEE-S--HHHHH-GGG---SS CS Methyltransf_5 82 kealaeanvtkvdgillDLGvSslqldkaerGFsfa 117 +e +++ + + +d++l+ LGv +++++k+++G+ + tr|W4ZC76|W4ZC76_STRPU 47 AERYQHLKENCCDFLLIQLGVCIFKYEKQKKGYGYV 82 566677777789*********************994 PP == domain 2 score: 7.5 bits; conditional E-value: 0.00071 EEEEEEE-S--HHHHH-GGG---S CS Methyltransf_5 93 vdgillDLGvSslqldkaerGFsf 116 +d++l+ LGv +++++k+++G+ + tr|W4ZC76|W4ZC76_STRPU 110 CDFLLIQLGVCIFKYEKQKKGYGY 133 799*******************99 PP >> tr|W4Y7A2|W4Y7A2_STRPU Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=3 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 6.1 0.0 0.0018 11 23 67 .. 110 154 .. 88 173 .. 0.83 2 ? -2.9 0.0 1 5.9e+03 223 241 .. 196 214 .. 193 215 .. 0.85 3 ! 6.7 0.0 0.0012 7.1 14 67 .. 264 318 .. 259 337 .. 0.82 4 ? -2.9 0.0 1 5.9e+03 223 241 .. 360 378 .. 357 379 .. 0.85 Alignments for each domain: == domain 1 score: 6.1 bits; conditional E-value: 0.0018 EEEES--TTSHHHHHHHTT--TTEEEEEES-HHHHHHHTT..... CS Methyltransf_5 23 vyiDaTlGaggHsealLeqlselrligidrDksalarakerLkef 67 +D+ Gag ++ l ++++e +++g+d+ +s++++a++ ++ tr|W4Y7A2|W4Y7A2_STRPU 110 RMLDVGCGAGLATQILAKKFPESHFVGVDIAQSMVDEANAEATRL 154 5789999***9999999*********************9876655 PP == domain 2 score: -2.9 bits; conditional E-value: 1 HHHHHHHEEEEEEEEEEES CS Methyltransf_5 223 leaalellakggrlavisF 241 ++ + ++++k+g l++i F tr|W4Y7A2|W4Y7A2_STRPU 196 IDDVKRVMKKDGTLSIIEF 214 66777899*********99 PP == domain 3 score: 6.7 bits; conditional E-value: 0.0012 HHT---TT-E.EEES--TTSHHHHHHHTT--TTEEEEEES-HHHHHHHTT..... CS Methyltransf_5 14 ellepkedgv.yiDaTlGaggHsealLeqlselrligidrDksalarakerLkef 67 ++l++ke g+ +D+ Gag ++ l ++++e +++g+d+ +s++++a++ ++ tr|W4Y7A2|W4Y7A2_STRPU 264 DFLKEKEMGIrVLDVGCGAGLATQILAKKFPESHFVGVDIAQSIVDEANAEATRL 318 5677777766367***********************************9876655 PP == domain 4 score: -2.9 bits; conditional E-value: 1 HHHHHHHEEEEEEEEEEES CS Methyltransf_5 223 leaalellakggrlavisF 241 ++ + ++++k+g l++i F tr|W4Y7A2|W4Y7A2_STRPU 360 IDDVKRVMKKDGTLSIIEF 378 66777899*********99 PP >> tr|W4XJA0|W4XJA0_STRPU Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.7 0.0 7.6e-05 0.44 19 62 .. 233 276 .. 218 309 .. 0.80 Alignments for each domain: == domain 1 score: 10.7 bits; conditional E-value: 7.6e-05 -TT-EEEES--TTSHHHHHHHTT--TTEEEEEES-HHHHHHHTT CS Methyltransf_5 19 kedgvyiDaTlGaggHsealLeqlselrligidrDksalarake 62 +++ + +D+ G+gg s + +q+++ r+igid+ + a+++ak tr|W4XJA0|W4XJA0_STRPU 233 ESGITVLDVGCGEGGASILMAKQYPNSRFIGIDICSYAIQQAKG 276 4567789***********************************97 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (309 nodes) Target sequences: 28594 (14266044 residues searched) Passed MSV filter: 886 (0.0309855); expected 571.9 (0.02) Passed bias filter: 478 (0.0167168); expected 571.9 (0.02) Passed Vit filter: 56 (0.00195845); expected 28.6 (0.001) Passed Fwd filter: 5 (0.000174862); expected 0.3 (1e-05) Initial search space (Z): 28594 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.29u 0.01s 00:00:00.30 Elapsed: 00:00:00.11 # Mc/sec: 40074.61 // [ok]